@software{carlisle_covid19_2020, location = {{Retrieved from https://covid19.bgcarlisle.com/}}, title = {Clinical trials stopped by Covid-19}, url = {https://covid19.bgcarlisle.com/}, organization = {{The Grey Literature}}, date = {2020-03}, author = {Carlisle, Benjamin Gregory} }
Carlisle BG. Clinical trials stopped by Covid-19 [Internet]. Retrieved from https://covid19.bgcarlisle.com/: The Grey Literature; 2020. Available from: https://covid.bgcarlisle.com/
Carlisle BG. Clinical trials stopped by Covid-19. Retrieved from https://covid19.bgcarlisle.com/: The Grey Literature; 2020. https://covid19.bgcarlisle.com/.
Carlisle, Benjamin Gregory. Clinical trials stopped by Covid-19. The Grey Literature, 2020, https://covid19.bgcarlisle.com/.
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Benjamin Gregory Carlisle PhD
Charité – Universitätsmedizin Berlin, Germany
Berliner Institut für Gesundheitsforschung (BIG) / Berlin Institute of Health (BIH)
QUEST – Quality | Ethics | Open Science | Translation
The Covid-19 outbreak that became a global pandemic in 2020 has disrupted lives, families, industries and entire nations. This project is a weekly-updated "living paper" that aims to quantify some of the effects of Covid-19 on the enterprise of human research.
The following table contains all registry entries from ClinicalTrials.gov whose overall status changed to Terminated, Suspended or Withdrawn since 2019-12-01. Investigator-provided reasons that explicitly mention Covid-19 are highlighted in green. Click a row of the table for more details about the trial.
To date, 2043 clinical trials have been stopped for reasons that explicitly cite Covid-19.
These data and figures are available to be downloaded under a Creative Commons By-Attribution Non-Commercial license. This data set was last updated 2021-01-29.
View full report (draft)NCT ID | Overall status | Brief title | Phase | Study type | Why stopped | Enrollment |
---|---|---|---|---|---|---|
NCT04729088 | Withdrawn | Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects | Phase 1 | Interventional | The sponsor will no longer develop the experimental drug. | Actual 0 |
NCT00520624 | Withdrawn | Treatment of Exercise-induced Laryngomalacia in Elite Athletes | N/A | Interventional | No patients willing to join | Actual 0 |
NCT03055312 | Terminated | Bicalutamide in Treatment of Androgen Receptor (AR) Positive Metastatic Triple Negative Breast Cancer | Phase 3 | Interventional | Actual 36 | |
NCT03260465 | Suspended | Clinical Study With the seleXys PC and the RM Pressfit Vitamys Cup | N/A | Interventional | The study has been transferred to the University Hospital Basel; 18.12.2020 (Prof. Karl Stoffel, Principal Investigator; Ilona Ahlborn, Study Coordinator) | Anticipated 60 |
NCT03540147 | Terminated | The Impact of Blood Flow Restriction (BFR) on Exercise and Hemodynamic Responses | N/A | Interventional | The number of subjects in this study was overestimated in the initial assessment. | Actual 20 |
NCT03540225 | Withdrawn | Vaginal Progesterone for the Prevention of Preterm Birth in Twins | Phase 3 | Interventional | Fail to sort out the logistics of study drugs due to funding problems | Actual 0 |
NCT04035317 | Withdrawn | Aesculus Hippocastanum L. on Fontan Circulation | Phase 2 | Interventional | The graduate student quit. | Actual 0 |
NCT04037631 | Terminated | Compare Visual Outcomes Using a New Diagnostic Device | Observational | recruitment | Actual 24 | |
NCT04139837 | Suspended | Frailty in Daily Practice: Screening, Consultation and Education Activities | Observational | COVID 19 pandemic | Anticipated 15000 | |
NCT04160429 | Suspended | Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations | Observational | pending amendment approval | Anticipated 100 | |
NCT04165733 | Suspended | Professional Quality of Life in German Psychiatrists | Observational | Recruitment was suspended with the begin of the COVID-19 pandemic as this potentially has an incluence on our outcomes | Anticipated 100 | |
NCT04200300 | Suspended | Professional Quality of Life in German Mental Health Nursing | Observational | Recruitment was stopped with the begin of the COVID-19 pandemic as this potentially has an incluence on our outcomes | Anticipated 100 | |
NCT04216056 | Suspended | Evaluation of a Frailty Intervention Program in Hong Kong | N/A | Interventional | COVID 19 pandemic | Anticipated 152 |
NCT03773185 | Suspended | A Comparative Study of Brain Structure and Amyloid Load in MCI Patients | Observational [Patient Registry] | Low recruitment rate | Anticipated 60 | |
NCT03831594 | Withdrawn | Combining Physical Therapy With Vestibular Stimulation to Improve Postural Stability in Pusher's Syndrome | N/A | Interventional | We were unable to recruit any suitable patients to this study | Actual 0 |
NCT03909750 | Suspended | Use of Autologous Stem/Stromal Cells In Chronic Lung Disorders: Obstructive (COPD) & Restrictive (RLD) | Phase 1 | Interventional | Withdrawn [COVID restrictions prevent patient enrollment or treatment. Clinical Trial facility is being closed due to viral limitations and loss of staff to perform] | Anticipated 50 |
NCT04000750 | Suspended | Time-Restricted Eating and Muscle Hypertrophy | N/A | Interventional | COVID-19 | Anticipated 40 |
NCT04030910 | Suspended | 'LIFEView' Audiovisual Technology: Virtual Travel to Support Wellbeing and Quality of Life at the End of Life | N/A | Interventional | Study on hold due to COVID-19 research restrictions for in-person research | Anticipated 92 |
NCT04043468 | Withdrawn | Audit and Feedback Interventions With Primary Care Nursing Teams | N/A | Interventional | COVID-19 | Actual 0 |
NCT04156672 | Withdrawn | Real World Study Of The Clinical Profile And Treatment Outcomes Of Advanced Therapies For Ulcerative Colitis In Portugal | Observational | Study was cancelled due to reclassification of study design. No subjects enrolled in the study. | Actual 0 | |
NCT04288076 | Withdrawn | The Brain and Lung Interaction (BALI) Study | N/A | Interventional | Low eligibility rate | Actual 0 |
NCT04605926 | Withdrawn | A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19 | Phase 3 | Interventional | Sponsor has currently elected to withhold study initiation | Actual 0 |
NCT04613271 | Suspended | Efficacy and Safety of Favipiravir in Covid-19 Patients in Indonesia | Phase 3 | Interventional | Study halted prematurely but potentially will resume, the protocol will be amended | Anticipated 210 |
NCT02013167 | Terminated | Blinatumomab Versus Standard of Care Chemotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL) | Phase 3 | Interventional | Actual 405 | |
NCT02830724 | Suspended | Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers | Phase 1/Phase 2 | Interventional | Requested by IRB | Actual 2 |
NCT03190941 | Suspended | Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients | Phase 1/Phase 2 | Interventional | Requested by IRB | Actual 6 |
NCT03238157 | Suspended | Steroids for Early Treatment of Radiation Retinopathy | Phase 2/Phase 3 | Interventional | Lack of funding | Anticipated 90 |
NCT03959046 | Suspended | GIST in Hematopoietic Stem Cell Transplantation/Bone Marrow Transplantation | N/A | Interventional | Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. | Anticipated 133 |
NCT03745326 | Suspended | Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients | Phase 1/Phase 2 | Interventional | Requested by IRB | Actual 4 |
NCT04102436 | Suspended | Non-Viral TCR Gene Therapy | Phase 2 | Interventional | Requested by IRB | Anticipated 210 |
NCT04169360 | Withdrawn | Safety and Preliminary Efficacy of ANS-6637 to Reduce Drug Craving and Harm in People With Opioid Use Disorder | Phase 2 | Interventional | The FDA determined that there is not adequate safety information to continue clinical investigations using ANS-6637 and Amygdala Neurosciences, the product company of ANS-6637, is no longer pursuing research with this compound. | Actual 0 |
NCT04308954 | Terminated | Neuroimaging GABA Physiology in Fragile X Syndrome | Phase 1 | Interventional | Difficulty with patient recruitment due to COVID-19 pandemic | Actual 17 |
NCT04534140 | Withdrawn | Skin Hydration in Persons With Acne After Dietary Supplementation With Botanical Antioxidants | N/A | Interventional | Contract not negotiated. | Actual 0 |
NCT01442402 | Terminated | APOL1 Gene Variants in African American Kidney Transplant Recipients | Observational | Lack of funding/resources | Actual 39 | |
NCT02470533 | Terminated | Transarterial Chemoembolization Versus Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma | Phase 2 | Interventional | Low accrual | Anticipated 100 |
NCT02939859 | Suspended | Use of Cellular Stromal Vascular Fraction in Multiple Sclerosis,Autoimmune, Inflammatory, Neurologic Conditions | N/A | Interventional | Withdrawn [COVID restrictions prevent patient enrollment or treatment. Clinical Trial facility is being closed due to viral limitations and loss of staff to perform] | Anticipated 100 |
NCT03088774 | Withdrawn | Comparing Satisfaction With a Participatory Driven Web-application and a Standard Website | N/A | Interventional | The primary trial was stopped. Since, a feasibility study showed that recruitment was not feasible. We obtain a recruitment rate of 15 %. | Actual 0 |
NCT03093948 | Terminated | Effect of Remote Ischemic Post-conditioning on Out-of-hospital Cardiac Arrest | N/A | Interventional | Overlap with other RCT | Actual 58 |
NCT03215355 | Withdrawn | Improving CBCT for Liver IG-SBRT Using Gadoxetate Disodium | Phase 4 | Interventional | Not approved | Actual 0 |
NCT03461419 | Suspended | Use of Stromal Vascular Fraction in Multiple Sclerosis | N/A | Interventional | Withdrawn [COVID restrictions prevent patient enrollment or treatment. Clinical Trial facility is being closed due to viral limitations and loss of staff to perform] | Anticipated 100 |
NCT04673175 | Suspended | Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation | Phase 1/Phase 2 | Interventional | Voluntary global product recall of Zerbaxa (ceftolozane and tazobactam) for injection (1.5g). | Anticipated 20 |
NCT03512405 | Suspended | Pembrolizumab and Blinatumomab in Treating Participants With Recurrent or Refractory Acute Lymphoblastic Leukemia | Phase 1/Phase 2 | Interventional | pending intrim analysis | Anticipated 36 |
NCT04536857 | Suspended | Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by Using Protein Misfolding Cyclic Amplification (PMCA) | Observational [Patient Registry] | The study has not been funded so far, but we will study it in the future. | Anticipated 302 | |
NCT01757223 | Withdrawn | Administration of AdVEGF-All6A+ to Myocardium of Individuals With Diffuse CAD Via Minimally Invasive Surgery | Phase 1/Phase 2 | Interventional | Closure due to lack of funding. | Actual 0 |
NCT02021734 | Suspended | Genetics of Mendelian Diseases in Qatar | Observational | Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. | Anticipated 400 | |
NCT00068003 | Suspended | Harvesting Cells for Experimental Cancer Treatments | Observational | Actual 2109 | ||
NCT02133196 | Suspended | T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer | Phase 2 | Interventional | Actual 3 | |
NCT02621021 | Suspended | A Prospective Randomized and Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab | Phase 2 | Interventional | Actual 20 | |
NCT03895359 | Withdrawn | Transarterial Chemoembolization (TACE) Versus TACE Plus Stereotactic Body Radiation Therapy (SBRT) in Liver Carcinoma | Phase 3 | Interventional | Erroneously entered in ClinicalTrials.gov. Replacement submission has been approved. | Actual 0 |
NCT04436120 | Terminated | Treatment Resistance Following Anti-cancer Therapies | N/A | Interventional | COVID-19 pandemic related enrollment pause | Actual 37 |
NCT04664543 | Terminated | Efficacy of Free Versus Low Residue Diet as Preparation for Screening Colonoscopy | N/A | Interventional | Organization and logistic problems due to COVID19 pandemy | Actual 100 |
NCT00578396 | Withdrawn | Phase I Biomarker Study of Dietary Grape-derived Low Dose Resveratrol for Colon Cancer Prevention | Phase 1 | Interventional | Non applicable clinical trial | Actual 0 |
NCT00579358 | Withdrawn | Molecular Basis of Congenital Heart Defects | Observational | Nonapplicable clinical trial | Actual 0 | |
NCT00580099 | Withdrawn | Assisted Exercise in Prematurity; Effects and Mechanisms | N/A | Interventional | Non applicable clinical trial | Actual 0 |
NCT00580697 | Withdrawn | Prevalence of Lower Urinary Tract Symptoms in Women With Gynecologic Malignancy Planning to Undergo Surgical Management | Observational | Nonapplicable clinical trial | Actual 0 | |
NCT00580918 | Withdrawn | Functional MRI Study of Attention in Normal Controls and Traumatic Brain Injured Patients | Observational | Nonapplicable clinical trial | Actual 0 | |
NCT00585403 | Withdrawn | Exercise Changes to Peripheral Blood Mononuclear Cells in Children | Observational | Nonapplicable clinical trial | Actual 0 | |
NCT00703443 | Withdrawn | The Genetics of Cardiomyopathy and Heart Failure | Observational | Non applicable clinical trial | Actual 0 | |
NCT00824395 | Withdrawn | The Genetics of Diabetes in Southern California Chinese Americans | Observational | Non applicable clinical trial | Actual 0 | |
NCT00894491 | Withdrawn | Complementary and Alternative Medical Trends: A Patient Survey in a University Based Clinic | Observational | Nonapplicable clinical trial | Actual 0 | |
NCT01386190 | Withdrawn | Impact of Exercise on Body Composition in Premature Infants | N/A | Interventional | Non applicable clinical trial | Actual 0 |
NCT04723173 | Suspended | Quality Control of CE-Certified Phonak Hearing Aids - 2020_43 | N/A | Interventional | Corona | Anticipated 11 |
NCT01543802 | Terminated | Study of Preoperative Therapy With Pazopanib (Votrient®) to Treat High-risk Soft Tissue Sarcoma | Phase 2 | Interventional | slow recruitment | Actual 21 |
NCT02510911 | Terminated | Does Caffeine Reduce Postoperative Bowel Paralysis After Elective Colectomy? | N/A | Interventional | lack of effect at interims analysis | Actual 60 |
NCT02614157 | Terminated | Lateral Lymph Node Dissection After Neoadjuvant Chemo-radiation in Advanced Low Rectal Cancer | N/A | Interventional | we can not recruit enough patients | Actual 51 |
NCT03051035 | Terminated | First-in-Human Study of KO-947 in Non-Hematological Malignancies | Phase 1 | Interventional | Due to a strategic business decision Kura has stopped development of KO-947. Neither safety nor efficacy reasons were the cause of study termination. | Actual 62 |
NCT03221842 | Terminated | Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients | Phase 3 | Interventional | The study was terminated early due to a business decision and not for safety reasons. | Actual 63 |
NCT03684889 | Suspended | CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma | Phase 1/Phase 2 | Interventional | Study halted pending review of safety event | Anticipated 112 |
NCT04245696 | Suspended | Bipolar RF Microneedling for Improved Laxity and Lift of the Submental and Neck Tissue and Effect on Elastin | N/A | Interventional | Study on hold, enrollment suspended at this time | Anticipated 60 |
NCT04313465 | Withdrawn | T-MACS Decision Aid: a Randomized, Controlled Point of Care Trial | N/A | Interventional | CI no longer wishes to complete this study due to Covid-19 | Actual 0 |
NCT00581152 | Withdrawn | The Role of TBX3 in Human ES Cell Differentiation | Observational | IRB suspension | Actual 0 | |
NCT02664571 | Withdrawn | Florbetaben as an Amyloid Plaque Marker in Elderly Patients With Focal or Disseminated Superficial Hemosiderosis | N/A | Interventional | experimental drug prohibited by the ANSM (French competent authority) | Actual 0 |
NCT02844582 | Terminated | Cabazitaxel and Prednisone in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer | Phase 2 | Interventional | Poor accrual of subjects onto study | Actual 2 |
NCT02970435 | Terminated | Evaluating the Impact of Video Discharge Instructions for Mohs Surgery Post-Operative Care | N/A | Interventional | Slow accrual | Actual 14 |
NCT03247244 | Terminated | Safety and Efficacy of Cannabis in Tourette Syndrome | Phase 2 | Interventional | Recruitment/enrollment took too long | Actual 15 |
NCT03739476 | Terminated | Clinical Trial With Quetiapine Prophylaxis Postoperative Delirium in High Risk Surgical Patients | Phase 3 | Interventional | Due to the crisis SARS-COV-2 pandemic: recruitment of patients for the trial is stopped, healthcare pressure generated, suspend the non-essential scheduled surgical activity and on June 30, 2020 medication expired, funding has been exhausted. | Actual 50 |
NCT03879824 | Terminated | Radial Versus Femoral Secondary Access During TAVI | N/A | Interventional | The PI and co-investigators would like to terminate the study given challenges with patient enrollment. | Actual 15 |
NCT03901378 | Withdrawn | Pembrolizumab With Chemotherapy in Metastatic or Unresectable High Grade Gastroenteropancreatic or Lung Neuroendocrine Carcinoma | Phase 2 | Interventional | Lack of accrual | Actual 0 |
NCT04002622 | Terminated | Study of TQB2450 Injection in Subjects With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma | Phase 2 | Interventional | The population of target indication is small and screening is difficult. | Actual 1 |
NCT04052269 | Suspended | Phosphodiesterase Inhibitors in Glaucoma Study (PhiGS) | Phase 3 | Interventional | suspended due to COVID | Anticipated 30 |
NCT04124510 | Terminated | Efficacy and Safety of Flutiform K-haler in Patients With Uncontrolled Asthma Following Mid-dose ICS/LABA DPI Therapy | Phase 3 | Interventional | The Contract of K-haler products had been terminated between Mundipharma and provider. Therefore, this clinical trial was terminated early. | Actual 20 |
NCT04181632 | Suspended | Evaluation of Pain Alleviating Strategies During Allergy Shots | N/A | Interventional | Due to the pandemic, enrollment was halted and patients were not coming to clinic. 40 of 100 patients were randomized. | Anticipated 100 |
NCT04299802 | Withdrawn | Percutaneous Ultrasonic Tenotomy Versus Platelet Rich Plasma for Gluteal Tendinopathy | N/A | Interventional | Study not being pursued | Actual 0 |
NCT04369001 | Withdrawn | Program ACTIVE: Phase 2 | N/A | Interventional | Due to covid-19 and social distancing, this study was terminated. | Actual 0 |
NCT03910439 | Terminated | Avelumab in Combination With Hypofractionated Radiotherapy in Patients With Relapsed Refractory Multiple Myeloma | Phase 2 | Interventional | Slow/Insufficient accrual. | Actual 4 |
NCT04456088 | Withdrawn | Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 (CANADA Trial) | Phase 2 | Interventional | Terminated (halted prematurely) | Actual 0 |
NCT04724512 | Suspended | Randomised Controlled Trial to Compare Tissue Reactions and Scarring With Polypropylene vs Polyglactin 910 Sutures in Periocular Skin: SUSY Study (SUture StudY) | Phase 4 | Interventional | setup activities were suspended due to COVID | Anticipated 44 |
NCT00738777 | Suspended | Pre-operative Hormonal Treatment for Hormone Receptor Positive Breast Cancer | Phase 2 | Interventional | in preparation for an amendment | Anticipated 250 |
NCT03284203 | Terminated | Feasibility of SpiroPD | N/A | Interventional | The aims represented in this study are also included in another, larger study of at-home COPD care. There was insufficient research team support to complete both protocols and the work would have been duplicative. Thus, we have terminated this study. | Actual 15 |
NCT03394196 | Terminated | RESIST-2: 2nd-line ART for HIV-2 Infection | N/A | Interventional | COVID-19 and Funding | Actual 152 |
NCT03149679 | Terminated | The p53 Colorectal Cancer Trial | Phase 2 | Interventional | The study was discontinued after the first pre-planned interim analysis due to insufficient response rates. | Actual 12 |
NCT03405142 | Suspended | Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck Cancer | Phase 2 | Interventional | Business decision | Anticipated 20 |
NCT03617146 | Terminated | Coaching and Education for Diabetes Distress | N/A | Interventional | Recruitment challenges. | Actual 19 |
NCT03630120 | Terminated | Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer | Phase 2 | Interventional | Lack of efficacy | Actual 6 |
NCT03944369 | Terminated | VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms | N/A | Interventional | COVID-19 pandemic | Actual 3 |
NCT03951662 | Withdrawn | Immunology of HIV and Alcoholic Hepatitis | Observational | Funding ended | Actual 0 | |
NCT03977675 | Terminated | The Role of HNKs in the Antidepressant Effect of Ketamine | Phase 1 | Interventional | PI left the institution | Actual 8 |
NCT04112017 | Terminated | A Study of YVOIRE Y-Solution 360 for Hand Augmentation to Correct Volume Loss | N/A | Interventional | Sponsor's decision | Actual 116 |
NCT04142359 | Terminated | PK Sub-Study of QUILT-3.032 (CA ALT-803-01-16) and of QUILT-2.005 (CA ALT-803-01-14) | Observational | Study was closed due to the recent pandemic and enrollment challenges. | Actual 1 | |
NCT04184037 | Terminated | iMeditate at Home for Older Adults With Mild Cognitive Impairment and Caregivers | N/A | Interventional | Study recruitment was suspended due to interruption of in-person testing after the start of the COVID19 pandemic in March 2020. The current study's protocol is being revised to be delivered fully remotely. | Actual 9 |
NCT04721171 | Suspended | Effectiveness of Electrical Neurostimulation in Cyclic Vomiting Syndrome. | N/A | Interventional | Due to COVID-19 | Actual 3 |
NCT02520557 | Terminated | An Exploratory Study of Genetic and Clinical Factors for Serious Skin Reactions Among Users of Eslicarbazepine Acetate | Observational | The study was not terminated for safety reasons. The sponsor was released from the postmarketing requirement to conduct the study | Actual 121 | |
NCT02602210 | Terminated | Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis | Phase 3 | Interventional | low inclusion rate | Actual 100 |
NCT02807753 | Terminated | The Hemophilia Ultrasound Project | Observational | Sponsor funding ended | Actual 18 | |
NCT02899650 | Terminated | Rates of Recovery From Strenuous Exercise in Physically Active Older Adults | N/A | Interventional | This was a research project that was conducted by a visiting scholar and his time for departure came earlier than the study completion. | Actual 60 |
NCT03433755 | Terminated | Safety and Efficacy of Evolocumab in Addition to Optimal Stable Background Statin Therapy in Chinese Subjects With Primary Hypercholesterolemia and Mixed Dyslipidemia | Phase 3 | Interventional | Prematurely Discontinued Amgen decision Amgen Decision | Actual 259 |
NCT03573336 | Terminated | Assess Safety and Efficacy of Vilaprisan in Subjects With Endometriosis | Phase 2 | Interventional | Due to a change in the development program, the study was closed prematurely. | Actual 8 |
NCT03646916 | Withdrawn | Intraoperative Dexamethasone and Its Effect on Hyperglycemia | Phase 4 | Interventional | Lack of patients | Actual 0 |
NCT03684668 | Terminated | Psychoeduc Interv. Through Meta-universes on Condom's Use Self - Efficacy and Sexual Behavior in Students of UAChile | N/A | Interventional | Data collection could not be completed in time and it has not been possible to continue due to the pandemic. Since it is not yet known when the face-to-face classes will resume, we moved on to the data analysis phase with the existing data. | Actual 90 |
NCT03976557 | Terminated | BIP CVC in Access Center at Danderyd Hospital, Stockholm, Sweden | N/A | Interventional | Due to Corona/Covid19 pandemic | Actual 19 |
NCT04028921 | Withdrawn | Activity, Adiposity, and Appetite in Adolescents 2 | Observational | Study Withdrawn | Actual 0 | |
NCT04493203 | Suspended | Nivolumab Plus Axitinib in Patients With Anti-PD1 Refractory Advanced Melanoma | Phase 2 | Interventional | Study to resume after FDA review | Anticipated 31 |
NCT04720742 | Suspended | Immune Therapy and Analytical Treatment Interruption in HIV+ Participants Who Received an Allogeneic Stem Cell Transplantation | Phase 2 | Interventional | Due to the COVID-19 pandemic the financial sponsor of the trial suspended the study funding due to funding limitations and based on various considerations, including the uncertainties of conducting the study in the volatile scenario of this pandemic. | Anticipated 5 |
NCT00144443 | Terminated | Kansas City Community Environmental Remediation And Training (KC CERT) | N/A | Interventional | Not completed | 200 |
NCT02684617 | Terminated | Study of Pembrolizumab (MK-3475) in Combination With Dinaciclib (MK-7965) in Hematologic Malignancies (MK-3475-155) | Phase 1 | Interventional | Business Reasons | Actual 75 |
NCT01794572 | Terminated | Phase 1-2 Study of Total Bone Marrow Irradiation With Helicoidal Tomotherapy in 1st Myeloma Relapse | Phase 1/Phase 2 | Interventional | Low patient recruitement rate and modification of the therapeutic standard | Actual 13 |
NCT03299231 | Suspended | Oscillating Positive Expiratory Pressure Devices and Acute Exacerbation of Chronic Obstructive Pulmonary Disease | N/A | Interventional | COVID 19 consequences | Anticipated 160 |
NCT03718325 | Suspended | Burst Spinal Cord Stimulation (Burst-SCS) Study | N/A | Interventional | Enrollment and interactions/interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. | Anticipated 20 |
NCT04115644 | Suspended | Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial | Phase 4 | Interventional | Covid-19 and we failed to submit annual report for 2017 and 2018 | Anticipated 400 |
NCT04197453 | Terminated | The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS) | Observational [Patient Registry] | Business decision | Actual 752 | |
NCT04473521 | Withdrawn | A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive | Phase 3 | Interventional | Study objectives no longer met business need | Actual 0 |
NCT04653168 | Suspended | A Study of LY3041658 in Healthy Participants | Phase 1 | Interventional | Enrollment on hold due to COVID-19 pandemic. | Anticipated 16 |
NCT02485652 | Terminated | Phase II Trial of HM61713 for the Treatment of ≥2nd Line T790M Mutation Positive Adenocarcinoma of the Lung | Phase 2 | Interventional | Study termination by the Sponsor | Actual 162 |
NCT03228654 | Terminated | Electrosurgical Unipolar Vessel Sealing in Vaginal Hysterectomy | Phase 4 | Interventional | No available device in the hospital to complete study | Actual 10 |
NCT03270722 | Withdrawn | Functional Luminal Imaging Probe (FLIP) Topography Use in Patients With Scleroderma and Trouble Swallowing | N/A | Interventional | We did not enroll any patients for logistic reasons. | Actual 0 |
NCT02309515 | Terminated | Lenalidomide in Improving Immune Response to Vaccine Therapy in Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Monoclonal B Cell Lymphocytosis | Phase 2 | Interventional | Slow Accrual | Actual 12 |
NCT02505204 | Suspended | PVB With vs. Without Clonidine for Ventral Hernia Repair | N/A | Interventional | Anticipated 60 | |
NCT02292121 | Terminated | Intestinal Permeability in Obesity | N/A | Interventional | lack of surgical controls | Actual 80 |
NCT02523768 | Terminated | Prevention in Recipients With Primary IgA Nephropathy of Recurrence After Kidney Transplantation: ATG-F Versus Basiliximab as Induction Immunosuppressive Treatment | Phase 4 | Interventional | Difficulties for recruting patients | Actual 117 |
NCT02667717 | Terminated | Efficacy and Safety of a Learning Program of Self- Rehabilitation Exercises by Mirror Therapy | N/A | Interventional | difficulties in including patients | Actual 34 |
NCT02866916 | Withdrawn | Study of SXL01 in Patients With Metastatic Castration-Resistant Prostate Cancer (PROSTIRNA) | Phase 1 | Interventional | Study cancelled | Actual 0 |
NCT02911220 | Terminated | Genetic Study of Familial Forms of Non-atopic Asthma | N/A | Interventional | not enough available families to get significant genetic results | Actual 2 |
NCT03547063 | Suspended | Responses to Appetite and Taste in the Brain Circuits That Control Eating Behaviour | Observational | COVID-19 | Anticipated 75 | |
NCT03806335 | Suspended | The Effectiveness of Local Infiltration Technique in Adult Tonsillectomy | N/A | Interventional | Lack of patients | Anticipated 60 |
NCT04243694 | Withdrawn | Sustainable Mindfulness and Resilience Training (SMART) | N/A | Interventional | Reduction in funding. | Actual 0 |
NCT03359174 | Terminated | An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis | Phase 2 | Interventional | low recruitment | Actual 2 |
NCT03707418 | Withdrawn | Bivalirudin vs Heparin in ECMO Patients | Phase 1 | Interventional | unable to secure funding | Actual 0 |
NCT03751423 | Suspended | Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion | Phase 3 | Interventional | Study on-hold due to COVID-19 pandemic restrictions. Will resume when possible. | Anticipated 123 |
NCT03809663 | Terminated | A Dose Ranging Placebo-Controlled Double-Blind Study to Evaluate the Safety and Efficacy of Tezepelumab in Atopic Dermatitis | Phase 2 | Interventional | Tezepelumab as a monotherapy in atopic dermatitis did not reach the targeted efficacy level pre-established for this patient population. | Actual 251 |
NCT03861182 | Terminated | Contribution of PRF in CDH in Children With Prothetic Patch Closure | Phase 3 | Interventional | Lack of staff | Actual 30 |
NCT03927625 | Withdrawn | Evaluation of Ascorbate-Meglumine Therapeutic for SRS | Phase 1 | Interventional | IRB determination | Actual 0 |
NCT04205071 | Withdrawn | Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal or Breast Cancer | Phase 1 | Interventional | PI decision | Actual 0 |
NCT04406064 | Withdrawn | Viral Specific T-cells for Treatment of COVID-19 | Phase 2 | Interventional | The use of steroids to treat COVID prevents the use of VSTs for these patients. The Principal Investigator does not feel the study had an expectation of enrolling patients as the treatment options for COVID have evolved. | Actual 0 |
NCT04713306 | Withdrawn | Gender Differences in Parkinsonian Patients- a Swedish Register Study | Observational [Patient Registry] | Actual 0 | ||
NCT04585932 | Withdrawn | Androgen Deprivation Therapy and Apalutamide With or Without Radiation Therapy for the Treatment of Biochemically Recurrent Prostate Cancer, RESTART Study | Phase 2 | Interventional | At the request of the ad interim Department Chairman due to PI is no longer at institution. | Actual 0 |
NCT01939431 | Terminated | Genetic and Other Aspects of Podoconiosis | Observational | Slow/Insufficient accrual | Actual 76 | |
NCT03478904 | Terminated | Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single Dose Administration Under Fasting Conditions in Prostate Cancer | Phase 1 | Interventional | Study drug is now commercially available in tablet format | Actual 1 |
NCT03854786 | Terminated | Aerobic Fitness in Overweight and Obese Individuals | N/A | Interventional | Due to Covid - 19 pandemic | Actual 11 |
NCT03978156 | Suspended | Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease | Phase 1 | Interventional | covid-19 Covid-19. | Anticipated 30 |
NCT02235545 | Terminated | Optisure Lead Post Approval Study | Observational | Abbott received FDA approval to transition the ongoing Optisure PAS to EP a new EP-PASSION Real World Evidence methodology | Actual 1735 | |
NCT03038750 | Suspended | Molecular Investigation of Genetic Factors in CArDiovascular Diseases Using an BIOresource of Healthy Volunteers | Observational | Study suspended as a precautionary measure, due to COVID-19, as the outbreak poses an increased risk to participants, due to potential exposure to the virus through attendance for study visits. | Anticipated 220 | |
NCT03040804 | Terminated | Low Dose Radiotherapy for Advanced Hidradenitis Suppurativa | N/A | Interventional | Infeasibility to continue study. | Actual 2 |
NCT03277586 | Terminated | Effects of Probiotics on Symptoms of Depression | Phase 3 | Interventional | COVID-19 | Actual 28 |
NCT03722459 | Suspended | Novel MRI Sequence- MR Fingerprinting | N/A | Interventional | Study suspended due to COVID-19 restrictions. Study will be resumed once plans for appropriate social distancing are in place. | Anticipated 105 |
NCT03760614 | Withdrawn | A Study of Entinostat and FOLFOX in Subjects With Pancreatic Adenocarcinoma | Phase 1 | Interventional | Lack of Funding | Actual 0 |
NCT03779828 | Terminated | Evaluating the Effectiveness of Telemonitoring System in the Management of Patients With CIDP | Observational | Due to logistical concerns | Actual 11 | |
NCT03808532 | Withdrawn | Moisturizer to Prevent Atopic Dermatitis | Phase 2 | Interventional | Lack of funding | Actual 0 |
NCT03852420 | Withdrawn | Boston Scientific's Single Shot LUMINIZE RF Balloon Catheter in the Treatment of Symptomatic, Drug Refractory Paroxysmal Atrial Fibrillation | N/A | Interventional | Sponsor discretion | Actual 0 |
NCT03927365 | Suspended | Muco-ciliary Cleansing of Lungs in COPD With and Without a Salt Particle Inhaler | N/A | Interventional | COVID-19 Pandemic | Anticipated 35 |
NCT03943407 | Withdrawn | Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% as a New Surrogate Model of Itch | N/A | Interventional | The Imiquimod 3.75% was ineffective | Actual 0 |
NCT04097353 | Suspended | Improving Health Behaviors for Pediatric Cancer Survivors | N/A | Interventional | Study recruitment of new participants was suspended during 2020 due to the Covid-19 pandemic. | Anticipated 75 |
NCT04218383 | Suspended | Transcranial Direct Current Stimulation for Impulsivity and Food-related Impulsivity in Obesity | N/A | Interventional | Coronavirus pandemic | Anticipated 30 |
NCT04243824 | Withdrawn | Ga-68 MAA Distribution in PAE Patients | Early Phase 1 | Interventional | Lack of funding | Actual 0 |
NCT04373083 | Withdrawn | Anti-PD-1 Antibody Treatment With Cemiplimab and Radiotherapy in Early-stage Classical Hodgkin Lymphoma | Phase 2 | Interventional | Business Decision | Actual 0 |
NCT04408872 | Withdrawn | EUS vs EGD in Emergency Room Patients Referred for EGD | N/A | Interventional | Study was not approved by the institution's scientific committee. | Actual 0 |
NCT04426357 | Terminated | A Study to Evaluate the Effect of Renal Impairment on JNJ-64417184 and Its Two Minor Metabolites JNJ-68294291 and JNJ-65201526 in Adult Participants | Phase 1 | Interventional | company decision | Actual 6 |
NCT04477954 | Terminated | Hyperbaric Oxygen as an Adjuvant Treatment for Patients With Covid-19 Severe Hypoxemia | Phase 2 | Interventional | Investigators and Ethic Committee endorsed early suspension of the protocol because of superiority and safety. For the interim analysys, the statistical methodology presented by Pocock was followed. | Actual 40 |
NCT04574973 | Terminated | Optimizing Transcranial Direct Current Stimulation for Motor Recovery From Severe Post-stroke Hemiparesis | N/A | Interventional | Relocation of PI | Actual 4 |
NCT04586777 | Terminated | Effects of Transvertebral Direct Current Stimulation in Humans | N/A | Interventional | Relocation of PI | Actual 27 |
NCT03798678 | Suspended | CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple Myeloma | Phase 1 | Interventional | DLT evaluation of the current dose level | Anticipated 36 |
NCT04707638 | Withdrawn | Neurophysiological Characteristics of Subthalamic Deep-brain Stimulation | Observational [Patient Registry] | Ethics application has not been completed yet | Actual 0 | |
NCT02519738 | Terminated | Granulation Tissue Treatment: Silver Nitrate vs Kenalog vs Washcloth Abrasion | Phase 3 | Interventional | enrollment difficulties | Actual 52 |
NCT02543957 | Withdrawn | Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With Cholangioscopy | Observational | Funding not received. | Actual 0 | |
NCT02992340 | Terminated | Varlitinib in Combination With Gemcitabine and Cisplatin for Treatment naïve Advanced or Metastatic BTC | Phase 1/Phase 2 | Interventional | Sponsor decided to terminate the study and not proceed to Phase 2. | Anticipated 204 |
NCT03334227 | Terminated | High Flow Nasal Cannula in Severe Sepsis | N/A | Interventional | low recruitment | Actual 39 |
NCT03346577 | Terminated | Endovascular Treatment of Peripheral Artery Disease | Observational [Patient Registry] | Termination of collaboration | Actual 60 | |
NCT03397173 | Suspended | TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid | Phase 2 | Interventional | Administrative hold | Anticipated 28 |
NCT03519061 | Withdrawn | Impact of Budesonide Irrigations on Patients With Chronic Rhinosinusitis and Impact on Sinus Surgery Rates | Phase 2/Phase 3 | Interventional | Unable to obtain FDA exemption | Actual 0 |
NCT03555656 | Terminated | Repeated Educational Intervention for the Prevention of Diabetic Foot Ulcers in High-risk Patients | N/A | Interventional | Futility analysis suggested termination | Actual 89 |
NCT02495103 | Terminated | Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma | Phase 1/Phase 2 | Interventional | Vandetanib is no longer available as Sanofi has decided not to provide additional drug. All subjects are off-study. | Actual 7 |
NCT03728205 | Withdrawn | Yoga for Solid Tumor | N/A | Interventional | Covid-19 | Actual 0 |
NCT03787147 | Withdrawn | Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Adult Patients for Pain Control During Spinal Injections (SI) | Phase 2 | Interventional | Never started the study cause of the lack of funding | Actual 0 |
NCT04085679 | Terminated | Multidisciplinary Mobile Unit for Preventing Hospitalization of Nursing Home Residents | Observational | The local Healthcare authorities extended the planned intervention to all nursing homes of the district after the emergence of multiple outbreaks of severe COVID-19 in several nursing homes. | Actual 13 | |
NCT04123756 | Terminated | Predicting Outcome Following Standardized Exercise Therapy in Knee Osteoarthritis Patients | Observational | Recruitment issues due to the corona virus and lack of funding to continue | Actual 12 | |
NCT04134143 | Terminated | Multiple Applications of ExpressGraft-C9T1 Skin Tissue as a Treatment for Diabetic Foot Ulcers | Phase 1 | Interventional | Business decision - not related to product quality or safety concerns | Actual 6 |
NCT04144634 | Terminated | Feasibility of Additional Physiotherapy for Patients Aged 75 and Older | Phase 2 | Interventional | Terminated due to COVID-19 | Actual 15 |
NCT04189991 | Suspended | Oxygen Titration Protocol for Exertion of COPD Patients by an Automated Adjustment Device | N/A | Interventional | Recruitment has not started yet due to COVID pandemic. | Anticipated 25 |
NCT04386447 | Withdrawn | Phase II RCT to Assess Efficacy of Intravenous Administration of Oxytocin in Patients Affected by COVID-19 | Phase 2 | Interventional | The study was not approved by the Italian Medicines Agency (AIFA). | Actual 0 |
NCT04656704 | Withdrawn | Hyaluronidase in Treating Oral Microstomia in Patients With Sclerosing Skin Disease | Early Phase 1 | Interventional | PI no longer pursuing clinical trial | Actual 0 |
NCT03421106 | Terminated | A Multilevel Intervention in the Hunger Relief Network to Improve Diet Among Adults Experiencing Food Insecurity | N/A | Interventional | Data collection was halted prematurely due to COVID-19. | Actual 504 |
NCT04170959 | Terminated | The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC | Phase 2 | Interventional | Loss of external funding | Actual 3 |
NCT04349930 | Withdrawn | The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC) | Phase 1 | Interventional | Need to obtain IND approval. | Actual 0 |
NCT04351516 | Withdrawn | Test and Treat COVID 65plus+ | Phase 2/Phase 3 | Interventional | No Patients enrolled | Actual 0 |
NCT03582046 | Terminated | Targeting Abdominal Perfusion Pressure in Septic Shock | N/A | Interventional | Lack of Enrollment | Actual 12 |
NCT03817281 | Withdrawn | Collective Accuryn Physiologic Signals and Signatures | Observational [Patient Registry] | Lack of Enrollment | Actual 0 | |
NCT04194528 | Terminated | S1916 Digital Medicine Program for Pain Control in Cancer Patients | N/A | Interventional | Study sponsor withdrew support. | Actual 2 |
NCT04690868 | Suspended | A Study to Compare PK, PD and Safety of the AD-213-A and AD-2131 | Phase 1 | Interventional | Rescheduled Study | Anticipated 40 |
NCT01324908 | Terminated | Biomarkers in Predicting Response in Patients With Graft-Versus-Host Disease Undergoing Extracorporeal Photophoresis | N/A | Interventional | Low accrual | Actual 85 |
NCT03154710 | Suspended | Relevance of a Web-mediated Follow up in Patients Having a Lymphoma With a High Risk of Relapse in Complete or Partial Response | N/A | Interventional | Negative interim analysis | Actual 52 |
NCT03597347 | Terminated | Trial of Inhaled Molgramostim in CF Subjects With NTM Infection | Phase 2 | Interventional | Recruitment for trial stopped early due to limitations from COVID-19, additionally changes in the standard of care for CF patients during the study period resulted in confounding of the primary endpoint. | Actual 14 |
NCT04060225 | Terminated | Effects of High Caffeine Content Coffee on Blood Pressure in Young Adults | N/A | Interventional | not possible to enroll during COVID pandemic | Actual 1 |
NCT04264156 | Suspended | A Safety and Efficacy Study of Lucinactant for Inhalation in Preterm Neonates 26 to 32 Weeks GA | Phase 2 | Interventional | Corporate business reasons | Actual 12 |
NCT04372940 | Suspended | Tranexamic Acid in Gender Mastectomy | Phase 4 | Interventional | Suspended due to COVID | Anticipated 50 |
NCT04373603 | Suspended | Use of Tranexamic Acid in Facial Fillers | Phase 4 | Interventional | Suspended due to COVID | Anticipated 40 |
NCT01507506 | Terminated | Phase III Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of Glioblastoma | Phase 3 | Interventional | Actual 180 | |
NCT03420976 | Withdrawn | Novel Supplement-based Therapy for the Treatment of Small Intestinal Bacterial Overgrowth | Early Phase 1 | Interventional | PI no longer in practice. | Actual 0 |
NCT01824823 | Terminated | Afatinib After Chemoradiation and Surgery in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck at High-Risk of Recurrence | Phase 2 | Interventional | Slow accrual | Actual 3 |
NCT04131322 | Terminated | Loss of Response of Adalimumab Biosimilar vs Adalimumab Original, in Inflammatory Bowel Disease. | Phase 4 | Interventional | Sponsor cancellation | Actual 24 |
NCT04589572 | Suspended | Extreme Lateral Interbody FusionFUSION (XLIF) Versus Posterior Lumbar Interbody Fusion (PLIF) | N/A | Interventional | Because of COVID-19 | Anticipated 40 |
NCT01939691 | Terminated | Macular Edema Nepafenac vs. Difluprednate Uveitis Trial | Phase 4 | Interventional | Difficulty enrolling | Actual 9 |
NCT02111382 | Suspended | Electroencephalography Activity in Individuals With Nonspecific Chronic Low Back Pain After Cranial Osteopathic Manipulative Treatment | N/A | Interventional | The pilot study demonsttated some new concerns about methodology. So we decided to suspended temporarily to added new settings to study design. | Anticipated 81 |
NCT02943837 | Withdrawn | EUS-guided Fine Needle Aspiration (EUS-FNA) Versus EUS-guided Fine Needle Biopsy (EUS-FNB) for Diagnosis of Subepithelial Tumors | N/A | Interventional | Funding issues | Actual 0 |
NCT03087097 | Terminated | Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition | Phase 1 | Interventional | COVID-19 pandemic and resource constraints | Actual 5 |
NCT02195024 | Terminated | Cardiac MRI After Pacemaker Replacement | Phase 4 | Interventional | PI changed affiliation not beening allowed to continue the trial in further cooperation. The sub-investigators did not see any option to continue the trial and made the decision to terminate the study. | Actual 23 |
NCT02961114 | Withdrawn | Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy | Phase 1/Phase 2 | Interventional | COVID restrictions prevent patient enrollment or treatment. Clinical Trial facility is being closed due to viral limitations and loss of staff to perform | Actual 0 |
NCT04008303 | Withdrawn | Outcomes of Migraine Surgery | Observational | No participants enrolled since this study open. The Primary research member (medical school student) is no longer available to do this study | Actual 0 | |
NCT00794339 | Terminated | Phase II Trial of 64Cu-ATSM PET/CT in Cervical Cancer | Phase 2 | Interventional | transfer of funding | Actual 73 |
NCT02591173 | Terminated | Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure | Early Phase 1 | Interventional | Difficulty recruiting | Actual 7 |
NCT03011671 | Suspended | Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma | Phase 1 | Interventional | Initial enrollment goal met. Pending funding to expand study. | Anticipated 24 |
NCT03028740 | Terminated | AURORA: Phase 3 Study for the Efficacy and Safety of CVC for the Treatment of Liver Fibrosis in Adults With NASH | Phase 3 | Interventional | Study stopped due to lack of efficacy. | Actual 1779 |
NCT03059446 | Terminated | Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis | Phase 2 | Interventional | Study stopped due to lack of efficacy | Actual 187 |
NCT03329378 | Suspended | Neoadjuvant Dose-Dense For Early Her2Neu Positive Breast Cancer | Phase 2 | Interventional | Data Safety Monitoring Board is in agreement with the study findings so far and the stopping rule has been met, which suspends the study treatment arms. | Anticipated 75 |
NCT04017910 | Suspended | Automated 3D Ultrasound-based Surveillance of Arteriovenous Fistula Maturation for Post-operative Hemodialysis Patients | Observational | to address inquiry. | Anticipated 100 | |
NCT04086927 | Withdrawn | Unna Boots for Ankle Fracture Swelling | N/A | Interventional | no funding | Actual 0 |
NCT04281238 | Suspended | The Effects of Yoga Training in Ankylosing Spondylitis Patients | N/A | Interventional | Because of Covid-19 | Anticipated 60 |
NCT04283526 | Withdrawn | Study of Select Combinations in Adults With Myelofibrosis | Phase 1 | Interventional | Sponsor Decision | Actual 0 |
NCT03789487 | Terminated | Electrical Optimization of Cardiac Resynchronization Therapy in Non-responder Patients | N/A | Interventional | the end of inclusion period | Actual 27 |
NCT02212015 | Terminated | Evaluation of Votrient in Angiosarcoma | Phase 2 | Interventional | Due to interim analysis' results and definitions fixed in protocol | Actual 26 |
NCT02336984 | Withdrawn | A Phase I/II Trial of HER-2/Neu Pulsed DC1 Vaccine Combined With Trastuzumab for Patients With DCIS | Phase 1/Phase 2 | Interventional | PI left Abramson Cancer Center and study never opened at Moffitt Cancer Center. | Actual 0 |
NCT03516903 | Terminated | Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI | Phase 2/Phase 3 | Interventional | Due to the COVID-19 pandemic. With a second wave just beginning, and considering that we are testing an immunosuppressant in patients with high risk for COVID-19 complications, we would not be able to re-start recruitment safely in the near future. | Actual 35 |
NCT03942276 | Terminated | Effects of Different Exercises Interventions in Post-menopausal Women | N/A | Interventional | Participants constantly reported knee pain. | Actual 60 |
NCT04259840 | Terminated | Clinical Outcomes of Resective Surgical Treatment of Peri-Implantitis With or Without Implantoplasty | Observational | COVID-19 pandemic | Actual 41 | |
NCT04474626 | Withdrawn | Isoquercetin in Sickle Cell Anemia | Phase 2 | Interventional | Trial did not activate | Actual 0 |
NCT04483687 | Withdrawn | Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Have an Inadequate Response to Biologic Disease-Modifying Antirheumatic Drug Therapy | Phase 3 | Interventional | Development program terminated | Actual 0 |
NCT04483700 | Withdrawn | Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Are Naive to Biologic Disease-Modifying Antirheumatic Drug Therapy | Phase 3 | Interventional | Development program terminated | Actual 0 |
NCT01217047 | Terminated | Study on Functional Electrical Stimulation (FES) Cycling Following Spinal Cord Injury | Phase 2/Phase 3 | Interventional | Lack of funding | Actual 11 |
NCT01695473 | Terminated | Neoadjuvant BKM120 in High-risk Prostate Cancer | Phase 2 | Interventional | Lack of Accrual | Actual 11 |
NCT03062553 | Withdrawn | Enhancement of Treatment of Delusions in Schizophrenia Through Neuromodulation | N/A | Interventional | Testing for this study remained in the pilot stages due to optimization of the tACS equipment. There are no clinical results to report. | Actual 0 |
NCT03585062 | Terminated | Trial of Neoadjuvant Chemotherapy With S1 Plus Paclitaxel-albumin on Pancreatic Cancer | Phase 2 | Interventional | The paclitaxel-albumin halt production. | Actual 40 |
NCT03929601 | Suspended | Rituximab and Abatacept for Prevention or Reversal of Type 1 Diabetes | Phase 2 | Interventional | Enrollment suspended by Sponsor. | Anticipated 36 |
NCT04002635 | Withdrawn | Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS) | Phase 4 | Interventional | Practical issues | Actual 0 |
NCT04300881 | Terminated | Treatment of Post-Ocriplasmin Therapy Vitreolysis Induced Subretinal Fluid With Eplerenone (Mineralocorticoid Antagonists) | Phase 2 | Interventional | Enrollment | Actual 2 |
NCT04454398 | Withdrawn | Study to Evaluate STI-1499 (COVI-GUARD) in Patients With Moderate COVID-19 | Phase 1 | Interventional | Difficulty recruiting | Actual 0 |
NCT04702230 | Terminated | Value of Functional Magnetic Resonance Imaging of Hepatocellular Carcinoma After Transarterial Chemoembolization or Transarterial Radioembolization | Observational | Treatment practice unexpectedly changed during the course of the study. Majority of follow-up MRI performed in external institutions. Consequently, the planned number of participants could not be reached. | Actual 32 | |
NCT00358657 | Terminated | Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders | Phase 2 | Interventional | Low accrual | Actual 14 |
NCT03091478 | Terminated | Pembrolizumab in Patients With Leptomeningeal Disease | Phase 2 | Interventional | Low Accrual | Actual 13 |
NCT01569035 | Terminated | Warfarine in Unexplained Oligohydramnios | Phase 4 | Interventional | Actual 200 | |
NCT01688284 | Terminated | The Role of Uterine NK Cells and T Cell Cytokines in Recurrent Miscarriage | N/A | Interventional | Actual 500 | |
NCT03412734 | Terminated | Vaginal Preparation Prior to Hysterectomy | Phase 4 | Interventional | The institutional review board recommended the study stop enrollment prior to achieving its initial sample size for patient safety. | Actual 94 |
NCT02601391 | Withdrawn | An Evaluation of an Adapted STEPPS Group Within Forensic Services | N/A | Interventional | Not able to run research in the service. Research terminated. | Actual 0 |
NCT03367195 | Terminated | Efficacy and Safety of DLBS2411 in the Management of GERD | Phase 3 | Interventional | Very low recruitment rate. The Study Site classifies as tertiary referral hospital. Therefore, GERD Patients being referred to the site are mostly those with comorbidities included in the exclusion criteria. | Actual 32 |
NCT03700723 | Terminated | Comparison of the Efficacy & Safety of Resusix With FP24 in Patients With Acquired Coagulopathy | Phase 2 | Interventional | Convenience of Government Funding Sponsor | Actual 4 |
NCT03713684 | Terminated | Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Alone or in Combination With Oral Antidiabetic Drug(s) | Phase 3 | Interventional | Sponsor decision to cancel TRIAL, not related to safety concern | Actual 370 |
NCT03770728 | Terminated | Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Alone or in Combination With Sulfonylurea | Phase 3 | Interventional | Sponsor decision to cancel TRIAL, not related to safety concern | Actual 312 |
NCT03829007 | Terminated | PD-L1 ImagiNg to prediCt Durvalumab Treatment Response in HNSCC | Phase 1/Phase 2 | Interventional | Hampering patient enrolment after registration of first line pembrolizumab | Actual 33 |
NCT01679561 | Withdrawn | Intralipid Therapy for Recurrent Implantation Failure and Recurrent Miscarriages: Is it a Hope or Myth?A Randomized Clinical Trial | Phase 4 | Interventional | Actual 0 | |
NCT01718340 | Withdrawn | Effectiveness of Metformin in Recurrent Miscarriage in a Woman With Hyperinsulinaemia | Phase 4 | Interventional | Actual 0 | |
NCT02591953 | Terminated | Prospective Clinical Analysis of Ultrasound-guided Biceps Corticosteroid Injections | N/A | Interventional | Unable to meet enrollment and follow up criteria | Actual 25 |
NCT00279851 | Withdrawn | Blood Sugars in Children With Idiopathic Seizures. | Observational | Actual 0 | ||
NCT00484172 | Withdrawn | Genomic Search for Childhood Obesity Genes-A Pilot Study | Observational | Study Withdrawn due to Investigator leaving | Actual 0 | |
NCT02402829 | Terminated | A Study Comparing Factor Level and Inhibitor Titer Testing Results Drawn From Central Venous Lines and Venipuncture | Observational | lack of participation or interest in other sites. | Actual 3 | |
NCT03093935 | Terminated | StimRouter™ for Pain Management in Post-stroke Shoulder Pain | N/A | Interventional | Lack of subject participation | Actual 6 |
NCT00766142 | Terminated | Chemotherapy and Cetuximab in Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer | Phase 2 | Interventional | In 2008, new data highlighted that Cetuximab had no efficacy in case of KRAS mutation. As such, eligibility criteria were revised and limited to KRAS wild-type. Inclusions were thus slown down considerably, and the trial was stopped. | Actual 18 |
NCT00867789 | Terminated | Antibiotics Versus Placebo in the Treatment of Abscesses in the Emergency Department | N/A | Interventional | Slow enrollment due to subjects not meeting inclusion/exclusion criteria | Actual 140 |
NCT03327662 | Terminated | Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate Cancer | Phase 3 | Interventional | Underrecruitment | Actual 12 |
NCT03730571 | Terminated | The AbsorbaSeal Vascular Closure Device Trial | N/A | Interventional | Insufficient closure | Actual 9 |
NCT04340843 | Suspended | Testing the Combination of Belinostat and SGI-110 (Guadecitabine) for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma | Phase 2 | Interventional | Scheduled Interim Monitoring | Anticipated 26 |
NCT04441164 | Withdrawn | VERARE : Effectiveness of Virtual Motor Actions for Improving Walking in Patients With Post-resuscitation Muscle Weakness | N/A | Interventional | Submitted, denied (too much steps; project to be cut in several projects) | Actual 0 |
NCT00809692 | Withdrawn | In Vivo Assessment of Histamine Pharmacodynamics | N/A | Interventional | Study withdrawn and combined with a new protocol | Actual 0 |
NCT02389517 | Suspended | Lenalidomide With or Without Ixazomib Citrate and Dexamethasone in Treating Patients With Residual Multiple Myeloma After Donor Stem Cell Transplant | Phase 2 | Interventional | Enrollment on hold due to funding. | Anticipated 86 |
NCT02734589 | Terminated | Fecal Transplantation Using a Diet for Donor and Recipient in Refractory Colitis | N/A | Interventional | DSMB recommendation of stopping the trial after reviewing the interim data | Actual 54 |
NCT02771795 | Terminated | A Long-term Follow-up Study for Cardiac Safety in the Patients With HER2 (+) Breast Cancer Who Have Completed the SB3-G31-BC | Observational | Considering the life-threatening risk posed by COVID-19 disease to a fragile population, the Sponsor concluded that the benefit of continuing the study does not outweigh the risk to the safety of patients & site staffs. | Actual 549 | |
NCT03115190 | Terminated | Improving the Referral of Patients With Chest Pain | N/A | Interventional | The Philips Minicare has been taken off the market due to financial company issues that have nothing to do with the safety of the Minicare or the URGENT trial. | Actual 40 |
NCT03391791 | Terminated | Long Term Follow up of Subjects Exposed to Genetically Engineered T Cell Receptors | Observational | terminated after participants were enrolled | Actual 2 | |
NCT03496298 | Terminated | Effect of Efpeglenatide on Cardiovascular Outcomes | Phase 3 | Interventional | Sponsor decision to cancel TRIAL, not related to safety concern | Actual 4077 |
NCT03864367 | Withdrawn | Mobile Weight-Support Therapy (MWeST) for Mobility After Geriatric Fracture | Observational | PI decided to end the study | Actual 0 | |
NCT03926598 | Terminated | Guide To Goals: A Novel Care Coordination Tool for Children With Type Two Diabetes (T2D) | Observational | This study did not complete enrollment due to COVID-19. Institutional constraints prevented this study from continuing and the study team no longer wishes to pursue this project. | Actual 6 | |
NCT04037319 | Suspended | Atrial Fibrillation After Surgery for Colorectal Cancer | Observational | Study recruitment has been halted due to the Pandemic. It is anticipated that recruitment will restart in March 2021. | Anticipated 720 | |
NCT04197011 | Suspended | Advanced Prosthetic Devices for Lower Limb Amputees | Observational | Recruitment not currently possible owing to current ongoing COVID-19 pandemic. | Actual 19 | |
NCT04253665 | Suspended | Nursing Discharge Teaching for Multimorbid Inpatients | N/A | Interventional | Due to the COVID-19, the study has been suspended since November 2020 | Anticipated 180 |
NCT04699552 | Withdrawn | Effect of Laser Settings on Postoperative Voiding Symptoms in Patients Undergoing Holmium Laser Enucleation of the Prostate | N/A | Interventional | PI does not wish to move forward with the Study | Actual 0 |
NCT00202930 | Terminated | Use of Rituximab in Opsoclonus-Myoclonus in Children With Neuroblastoma | Phase 2 | Interventional | Closed early due to low accrual. | Actual 4 |
NCT02931851 | Suspended | Family Information Management in the Intensive Care Unit | N/A | Interventional | Actual 75 | |
NCT03719898 | Withdrawn | Brigatinib in Relapsed or Refractory ALK-Positive Anaplastic Large Cell Lymphoma | Phase 2 | Interventional | Slow accrual | Actual 0 |
NCT02570438 | Terminated | Improving Surgical Safety of Seniors Through Preoperative Cognitive Screening | Observational | This study was terminated prior to its planned enrollment due to low recruitment rates at the time that the funding for the study was completed. | Actual 500 | |
NCT03205046 | Terminated | A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies | Phase 1/Phase 2 | Interventional | Sponsor's decision not to pursue further development of the combination in DLBCL | Actual 25 |
NCT03342365 | Terminated | Evaluation of Intestinal Bacterial and Fungal Translocation and Intestinal Microbiota in Febrile Neutropenic Patients in Pediatric Onco-hematology | Observational | 10 patients inclued instead of 50 | Actual 10 | |
NCT03620149 | Terminated | Reduced Dose-density of Denosumab for Unresectable GCTB | Phase 2 | Interventional | Poor accrual | Actual 2 |
NCT04132739 | Terminated | Piloting Diet and Exercise Interventions in Older Hispanics With Diabetes | N/A | Interventional | COVID-19 | Actual 39 |
NCT04187612 | Suspended | Association of Body Fluid Distribution With Obstructive Sleep Apnea in Pregnant Women With Body Mass Index ≥ 40 kg/m2 | Observational | Virtual/telephone appointments for patients due to Covid restrictions have halted this research. We may resume when we have the resources, however the current plan is to publish the data we have so far. | Anticipated 52 | |
NCT02272348 | Terminated | Self-management of Type 1 Diabetes Under Functional Insulin Therapy | N/A | Interventional | Change in methodology too important - end of randomization | Actual 13 |
NCT02528071 | Terminated | Prognostic Value of a Diaphragmatic Endurance Test in Patients With Amyotrophic Lateral Sclerosis | Observational | lack of inclusion | Actual 136 | |
NCT02853162 | Terminated | Ablative tReatment of Inoperable REnal Cell Carcinoma Using STereotactic Body Radiotherapy (ARREST-study) | Phase 2 | Interventional | Slow inclusion | Anticipated 30 |
NCT02446886 | Terminated | Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS | Phase 4 | Interventional | Slow enrollment | Actual 15 |
NCT03219372 | Terminated | Pravastatin Intervention to Delay Hepatocellular Carcinoma Recurrence | Phase 2 | Interventional | Study discontinued due to low accrual. | Actual 1 |
NCT00127543 | Withdrawn | Kid Cards: Teaching Kids About Medicines | N/A | Interventional | Not completed | Actual 0 |
NCT01895881 | Withdrawn | Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial | Phase 2 | Interventional | Unable to Recruit Participants | Actual 0 |
NCT03327324 | Suspended | Improving Sleep Using Mentored Behavioral and Environmental Restructuring | N/A | Interventional | Due to the COVID19 pandemic, as of March 14, 2020, all nursing homes in New York were on lockdown, as a result, all of the recruitment efforts have been on pause until further notice. | Anticipated 120 |
NCT03936595 | Terminated | Recovery of Performance, Muscle Damage and Neuromuscular Fatigue Following Muscle Power Training | N/A | Interventional | There was a high drop-out rate and we were unable to recruit new subjects. | Actual 10 |
NCT04001738 | Terminated | Evaluation of Direct Transfer to Angiography Suite vs. Computed Tomography Suite in Endovascular Treatment: Randomized Clinical Trial (ANGIOCAT) | N/A | Interventional | Intermediate analysis | Actual 174 |
NCT04124783 | Withdrawn | Study to Evaluate the Effects of the Cooling Bolero in Women With Menopause Symptoms | N/A | Interventional | The company no longer provided the device. | Actual 0 |
NCT01174121 | Suspended | Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer | Phase 2 | Interventional | Actual 91 | |
NCT03818542 | Terminated | A Study to Assess the Effects of Multiple Study Drug Regimens in Subjects With Newly Diagnosed Locally Advanced Head and Neck Squamous Cell Carcinoma | Phase 1 | Interventional | Strategic considerations | Actual 3 |
NCT04692246 | Terminated | Effect of Essential Oils as Adjutants on the Treatment of Subjects With Periodontitis: Assessment of Metabolic Variables as Effect Modifiers | N/A | Interventional | Due to COVID-19 Pandemic | Actual 60 |
NCT03084510 | Withdrawn | REPRISE China - Clinical Evaluation in China | N/A | Interventional | study device was recalled. | Actual 0 |
NCT03412877 | Suspended | Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in People With Metastatic Cancer | Phase 2 | Interventional | Action taken by IRBO | Anticipated 270 |
NCT04034745 | Withdrawn | Open Label Study to Analyze the Effect of Telotristat Ethyl on Weight Regulation/Gain | Observational | lack of funding | Actual 0 | |
NCT03063359 | Terminated | Intranasal Fentanyl Versus Oral Morphine Sulfate in the Treatment of Pain in Pediatric Trauma | Phase 3 | Interventional | The new pain protocols imposed by the HAS make it difficult to include new patients in the study | Actual 22 |
NCT03327974 | Terminated | Evolution of Dark Ideas When Introducing or Switching an Antidepressant | N/A | Interventional | Problem on the app, questioned the feasability of the study | Actual 38 |
NCT03729063 | Terminated | Impact of Twice-daily Measurement of Expired CO During Hospitalization on Smoking | N/A | Interventional | Difficulty in recruiting, many patients with exclusion criteria | Actual 67 |
NCT04508868 | Terminated | Treatment of Depressive Symptoms in Older Individuals in Isolation During Covid-19 | N/A | Interventional | Study terminated due to changes in government restrictions. Collected data to be presented as a pilot study. | Actual 41 |
NCT04691726 | Suspended | Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia | Phase 4 | Interventional | Pandemia of the Covid-19 | Anticipated 150 |
NCT03808012 | Withdrawn | Predictability of the Ability to Perform an Emergency Stop After Surgery for Inguinal Hernia | N/A | Interventional | Unsuccessful recruitment | Actual 0 |
NCT04370938 | Withdrawn | Provider Burnout During COVID-19 | N/A | Interventional | No participants were enrolled and the study was never initiated. | Actual 0 |
NCT03253289 | Suspended | Meclizine for Hepatocellular Carcinoma | Phase 1 | Interventional | This study has been temporarily suspended to accrual by the Data Review Committee due to a protocol violation that recently occurred. The study will resume to accrual after the protocol has been amended and approved by the IRB and DRC. | Anticipated 13 |
NCT03964376 | Suspended | Nasal High Flow Therapy in Surgical Patients With Unrecognized Obstructive Sleep Apnea | N/A | Interventional | due to COVID-19 | Anticipated 190 |
NCT04531397 | Withdrawn | Efficacy and Safety of Dapagliflozin in Children With Proteinuric Chronic Kidney Disease | Phase 4 | Interventional | lack of funding | Actual 0 |
NCT03920878 | Withdrawn | Cataract DME - Peri vs. Intraop | Phase 2 | Interventional | The study team was unable to secure sufficient funding and administrative support. | Actual 0 |
NCT04464525 | Withdrawn | Omecamtiv Mecarbil Post-trial Access Study | Phase 3 | Interventional | Sponsor decision | Actual 0 |
NCT03641430 | Withdrawn | The Effects of Over-the-Counter Products on the Skin | N/A | Interventional | The study design will need to be changed completely becasue of the change of research interest. We have decided to withdraw the study. | Actual 0 |
NCT03641677 | Suspended | Increasing Lung Transplant Availability Using Normothermic Ex Vivo Lung Perfusion (EVLP) at a Dedicated EVLP Facility | N/A | Interventional | Data Monitoring Committee review triggered by protocol Halting Rule. | Anticipated 186 |
NCT00904345 | Terminated | Study of Radiation (RT) Concurrent With Cetuximab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (SCC) | Phase 2 | Interventional | Stopped early for funding and efficacy reasons. | Actual 23 |
NCT04258410 | Suspended | Quercetin for Cardio-Skeletal Muscle Health and Estrogen Deficiency | Phase 4 | Interventional | Investigator is revising protocol. | Anticipated 24 |
NCT01849783 | Terminated | Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma | Phase 2 | Interventional | Principal Investgator leaving institution | Actual 41 |
NCT03026127 | Suspended | A Novel Cognitive Reappraisal Intervention for Suicide Prevention | N/A | Interventional | Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. | Anticipated 90 |
NCT03158116 | Terminated | The Use of Inhaled Aztreonam in Children With a Tracheostomy Tube and Pseudomonas | Phase 4 | Interventional | IRB application expired. | Actual 6 |
NCT03161821 | Suspended | Circulating Tumor Cells in Solid Tumors | Observational | New enrollment and collection of blood samples paused while IRB reviews use of the investigational assay involved. | Anticipated 500 | |
NCT03334578 | Withdrawn | The Use of Gastrografin to Help Alleviate Bowel Obstruction in Gastroschisis Patients. | Phase 4 | Interventional | Lack of recruitment | Actual 0 |
NCT03615989 | Suspended | The Combined Effect of Dairy and/or Creatine and Exercise on Bone and Inflammation | N/A | Interventional | COVID-19 | Anticipated 15 |
NCT04060251 | Suspended | Is There an Alternative to Immediate Home Physical Therapy Following Total Knee Arthroplasty | N/A | Interventional | COVID-19 limitations on recruitment | Anticipated 87 |
NCT04230564 | Withdrawn | Acute Myeloid Leukemia Real World Treatment Patterns | Observational | Not pursued | Actual 0 | |
NCT04570449 | Withdrawn | Fluoxetine to Reduce Hospitalization From COVID-19 Infection (FloR COVID-19) | Early Phase 1 | Interventional | Study timeline is not feasible | Actual 0 |
NCT02156674 | Terminated | Naglazyme After Allo Transplant for Maroteaux-Lamy Syndrome | N/A | Interventional | Slow accrual | Actual 1 |
NCT04681027 | Suspended | Safety, Tolerability, Effectiveness, and Pharmacokinetic Data in Opioid-experienced Children | Phase 3 | Interventional | Study Suspended 06Feb2020 per FDA Request | Actual 15 |
NCT03672370 | Terminated | PMCF Study on the Safety and Performance of the Alloclassic Variall Cup Ceramic Bearing System in Total Hip Arthroplasty | Observational | Study terminated as CE marks of the devices used have not been renewed. | Actual 100 | |
NCT00256776 | Terminated | MMVAR - Velcade: Study of Velcade for the Treatment of Myeloma Patients After Autologous Transplantation | Phase 3 | Interventional | Actual 269 | |
NCT03552692 | Terminated | Use of Venetoclax as Single Agent in Patients With Relapsed/Refractory BCL-2 Positive Peripheral T Cell Lymphoma | Phase 2 | Interventional | efficacy lower than expected | Actual 22 |
NCT01984268 | Terminated | ACTHAR for Acute Treatment of Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate | Phase 2 | Interventional | Actual 15 | |
NCT02177838 | Terminated | Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer | N/A | Interventional | Slow accrual | Actual 8 |
NCT00700154 | Terminated | Insulin Infusion Diabetes Ulcer | N/A | Interventional | participants are no longer being examined or receiving intervention | Actual 40 |
NCT02818764 | Terminated | Delirium, Intraoperative Cerebral Perfusion and EEG Abnormalities After Total Hip Arthroplasty | Observational | COVID related limitations | Actual 3 | |
NCT03534219 | Withdrawn | Efficacy of the EarPopper Device in Children With Recurrent Otitis Media | N/A | Interventional | No participants enrolled | Actual 0 |
NCT03795623 | Suspended | Voices of Patients' Relatives to Support Weaning From Mechanical Ventilation | Phase 2/Phase 3 | Interventional | Only recruitment temporarily paused due to Covid-19 | Anticipated 354 |
NCT03966989 | Suspended | Improving Quality & Equity of Emergency Care Decisions (IQED) | N/A | Interventional | Suspended due to COVID-19 pandemic | Anticipated 80 |
NCT04552262 | Suspended | Study to Learn More About the Effect of a New Drug Called BAY2327949 on the Blood Flow Through Kidneys in Adult Participants With Moderate Chronic Kidney Disease | Phase 1 | Interventional | Temporary on hold. | Anticipated 22 |
NCT03761836 | Withdrawn | Evaluation and Adverse Event Surveillance for Initial Implementation of ShangRing Circumcision in Mozambique | N/A | Interventional | Funding no longer available | Actual 0 |
NCT04403646 | Terminated | Tannin Specific Natural Extract for COVID-19 Infection | N/A | Interventional | low rate of covid patients | Actual 124 |
NCT02916472 | Suspended | CyberCycling to Reduce Therapeutic Side Effects and Improve Quality of Life in AYA Cancers | N/A | Interventional | COVID-19 | Anticipated 20 |
NCT03096340 | Terminated | Safety and Pharmacokinetic Study of IT-141 in Monotherapy in Patients With Advanced Cancer | Phase 1 | Interventional | Terminated by sponsor. | Actual 10 |
NCT03162562 | Terminated | The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer | Phase 1 | Interventional | Sponsor Decision to discontinue long-term follow-up | Actual 10 |
NCT03782363 | Withdrawn | Study of Adoptive Immunotherapy in Relapsed and Non-resectable Sarcomas After Multimodal Treatment. | Phase 1 | Interventional | Initial version of the protocol not submitted and new version approved has a new sponsor and it has been added into Clinicaltrials by the new sponsor | Actual 0 |
NCT04209179 | Suspended | A Clinical Study Investigating the Safety, Tolerability, PK and PD of PCO371 in Patients With Hypoparathyroidism | Phase 1 | Interventional | Temporary halt due to adverse events | Anticipated 24 |
NCT04357028 | Suspended | Measles Vaccine in HCW | Phase 3 | Interventional | Failure of subject recruitment | Anticipated 200 |
NCT00637767 | Terminated | High-Dose Melphalan With or Without Radiolabeled Monoclonal Antibody in Treating Patients With Multiple Myeloma Undergoing an Autologous Stem Cell Transplant | Phase 2 | Interventional | Low recruitment | Actual 25 |
NCT04267679 | Withdrawn | Cannabidiol for Anxiety | Phase 2 | Interventional | Stopped due to COVID-19 pandemic. | Actual 0 |
NCT03090932 | Suspended | Longitudinal Study of Innate Lymphoid Cells in Peripheral Blood in ALS | Observational | Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. | Anticipated 250 | |
NCT03134027 | Suspended | Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers | Observational | Suspended due to COVID-19. | Anticipated 30 | |
NCT03802214 | Terminated | Ulcerative Colitis - Vedolizumab- With/Without Prior Exposure to Anti-TNF(Tumor Necrosis Factor)Therapy | Observational | Funding discontinued | Actual 1 | |
NCT03969940 | Withdrawn | Thermotherapy of Buruli Ulcer at Community Level in the Health District of Akonolinga | Observational | Lack of supply of comparator drug in country | Actual 0 | |
NCT04026334 | Terminated | Evaluation of V.A.C. VERAFLO CLEANSE CHOICE™ Dressing Using Normal Saline to Promote Increased Healthy Wound Bed Tissue | N/A | Interventional | Insufficient subject accrual rate | Actual 8 |
NCT04279665 | Suspended | Virtual Reality to Reduce Intra-procedural Anxiety and Sedation Needs During Procedures | N/A | Interventional | Equipment changed | Anticipated 20 |
NCT04338906 | Withdrawn | Combination Therapy With Camostat Mesilate + Hydroxychloroquine for COVID-19 | Phase 4 | Interventional | lack of public funding; planned control arm with Hydroxychloroquine treatment showed out as not being standard of care anymore as time evolved. | Actual 0 |
NCT04341441 | Terminated | Will Hydroxychloroquine Impede or Prevent COVID-19 | Phase 3 | Interventional | Interim analysis did not reveal any safety concerns by the DSMB, but unblinded data did not provide support to continue. Event rate did not meet projected magnitude; given low recruitment potential, it is unlikely that a positive result will occur. | Actual 624 |
NCT04609800 | Withdrawn | Study on the Utilization of Cabozantinib in Adult Patients With Advanced or Metastatic Renal Cell Carcinoma (RCC) in 2nd Line Treatment Following Prior Vascular Endothelial Growth Factor (VEGF)-Targeted Therapy Under Real-real Life Clinical Setting in France. | Observational | Unfavorable opinion of IRB/IEC | Actual 0 | |
NCT04675086 | Withdrawn | Aralast NP With Antiviral Treatment and Standard of Care Versus Antiviral Treatment With Standard of Care in Hospitalized Patients With Pneumonia and COVID-19 Infection | Phase 3 | Interventional | Administrative Decision | Actual 0 |
NCT03442985 | Terminated | An Efficacy and Safety Study of Palovarotene for the Treatment of MO | Phase 2 | Interventional | Trial was terminated early to analyze the accumulated data and evaluate the efficacy, safety and future of palovarotene in MO. | Actual 194 |
NCT03431740 | Suspended | FENO, Extended NO Analysis and NO/CO Diffusing Capacity in Thoracic Radiation Therapy | Observational | Study recruitment paused due to Corona-Pandemic | Anticipated 38 | |
NCT02730793 | Terminated | Aztreonam Aerosol to Treat Cystic Fibrosis Nasal Disease | Phase 2 | Interventional | terminated due to an inability to recruit study subjects | Actual 5 |
NCT02647762 | Terminated | CF101 Therapy Compared to Methotrexate Therapy for Active Rheumatoid Arthritis | Phase 3 | Interventional | Interim analysis results | Actual 244 |
NCT03344562 | Terminated | Cranial Electrical Stimulation (CES) as Treatment for Insomnia in Patients With Subacute Stroke | N/A | Interventional | Due to lack of resources (insufficient personnel) and due to technical problems with measurement of primary and secondary outcomes. | Actual 19 |
NCT03508219 | Suspended | POLish Bifurcation Optimal Treatment Strategy Study for Left Main Bifurcation Percutaneous Coronary Intervention (PCI) | N/A | Interventional | COVID-19 | Anticipated 260 |
NCT03824704 | Terminated | A Study to Evaluate Rucaparib in Combination With Nivolumab in Patients With Selected Solid Tumors (ARIES) | Phase 2 | Interventional | Sponsor made a business decision to discontinue the study due to low accrual. | Actual 1 |
NCT03939897 | Suspended | Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer | Phase 1/Phase 2 | Interventional | Other - Pending amendment | Anticipated 194 |
NCT04366791 | Suspended | Radiation Eliminates Storming Cytokines and Unchecked Edema as a 1-Day Treatment for COVID-19 | Phase 1/Phase 2 | Interventional | per PI: temporarily hold throughout month of Dec. | Anticipated 10 |
NCT04216316 | Suspended | Testing the Addition of an Anti-cancer Drug, M6620, to the Usual Treatments (Carboplatin and Gemcitabine) and to Avelumab for Non-small Cell Lung Cancer | Phase 1/Phase 2 | Interventional | Other - to reevaluate primary endpoint | Anticipated 106 |
NCT03516084 | Terminated | A Study of Niraparib as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Patients With Extensive Stage Small Cell Lung Cancer | Phase 3 | Interventional | As the treatment model of extensive-stage small cell lung cancer changed rapidly and the enrollment speed significantly lower than expected, ZaiLab decided to terminate this study | Actual 185 |
NCT01117779 | Terminated | Tracking Renal Tumors After Cryoablation Evaluation | Observational | Boston Scientific acquisition of BTG/Galil Medical - business decision made to stop follow-up early | Actual 250 | |
NCT03279068 | Terminated | Electronic Fetal Monitoring With and Without Pattern Interpretation | Observational | Civil unrest in region/country of study | Actual 637 | |
NCT03943706 | Withdrawn | E-Cigarette and Cigarette Nicotine Delivery and Abuse Liability in Cigarette Smokers and Dual Users | Observational | The investigator moved to another institution, therefore the study was never initiated. | Actual 0 | |
NCT03804164 | Withdrawn | Psycho-Educational Cognition Intervention in Patients With Blood and Lymph Cancer | N/A | Interventional | Feasibility | Actual 0 |
NCT03987347 | Withdrawn | Health Condition of Cannabis Consumers in the Canadian Population | Observational | No authorization from CLSA database scientific committee | Actual 0 | |
NCT03997981 | Suspended | Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY) | Observational | Enrollment on hold due to COVID-19 pandemic. | Anticipated 200 | |
NCT04153838 | Suspended | Estimating Premorbid Intellectual Functioning in Children and Measuring Change in Cognitive Functioning as Children Develop | Observational | Due to covid-19 restrictions on recruiting | Anticipated 100 | |
NCT04209556 | Withdrawn | A Study To Evaluate The Safety And Efficacy Of PF-06826647 In Participants With Moderate To Severe Ulcerative Colitis | Phase 2 | Interventional | The study was withdrawn following a strategic portfolio re-prioritization. | Actual 0 |
NCT04513782 | Suspended | The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss | Observational | On Hold due to COVID-19 outbreak | Anticipated 200 | |
NCT04549584 | Terminated | Neoadjuvant Chemotherapy Response in Metaplastic Carcinoma of Triple Negative Breast Cancer | Observational [Patient Registry] | due to poor enrolled patients | Actual 3 | |
NCT04576208 | Withdrawn | A Study to Evaluate the Impact of Management Strategies on Gastrointestinal-Related Adverse Events in Participants With Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations Receiving TAK-788 | Phase 2 | Interventional | Business Decision (no safety or efficacy concerns) | Actual 0 |
NCT00285363 | Withdrawn | Quality of Life Among Children and Adolescents With Cancer | Observational | Unable to reconcile record due to age | Actual 0 | |
NCT00777218 | Withdrawn | Cognitive Side Effects of Commonly Prescribed Medications in Pediatric Migraine | N/A | Interventional | Enrollment criteria was too challenging and Investigators changed Institutions | Actual 0 |
NCT00844740 | Withdrawn | Calcimimetics in Hypophosphatemic Rickets | N/A | Interventional | Actual 0 | |
NCT01051544 | Withdrawn | Study of First TIME Immunotolerance Induction in Severe Hemophilia A Patients With Inhibitor at High Risk of Failure: Comparison With FVIII Concentrates With or Without Von Willebrand Factor - RES.I.S.T. Naive | N/A | Interventional | complete per PI | Actual 0 |
NCT02481960 | Terminated | Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma | Phase 1/Phase 2 | Interventional | The decision to terminate the trial was based on the slow rate of recruitment across the programme of studies] | Actual 5 |
NCT02834455 | Terminated | Rational Approach to a Unilateral Pleural Effusion2 | N/A | Interventional | Patient inclusion cannot be reached within timelimits | Actual 200 |
NCT02994953 | Terminated | A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12) | Phase 1 | Interventional | The study got discontinued due to lack of efficacy | Actual 52 |
NCT03042897 | Withdrawn | Exercise and Diet Intervention in Promoting Weight Loss in Obese Patients With Stage I Endometrial Cancer | N/A | Interventional | PI left institution | Actual 0 |
NCT03120390 | Withdrawn | Physical Activity in Reducing Metabolic Dysregulation (MetD) in Obese Latina Breast Cancer Survivors | N/A | Interventional | PI left institution | Actual 0 |
NCT03272087 | Terminated | Rational Approach to a Unilateral Pleural Effusion | N/A | Interventional | Patient inclusion cannot be completed within time limits | Actual 120 |
NCT03449095 | Suspended | Understanding Alcohol Reward in Social Context | N/A | Interventional | COVID-19 | Anticipated 600 |
NCT03647722 | Terminated | Assessing the Induction of Long-term Immune Regulation Following Treatment With Lemtrada® (Alemtuzumab). | Observational | Study funding was terminated. | Actual 97 | |
NCT03739606 | Withdrawn | Flotetuzumab in Treating Patients With Recurrent or Refractory CD123 Positive Blood Cancer | Phase 2 | Interventional | RSS recommendation | Actual 0 |
NCT03763929 | Terminated | Efficacy and Safety of Trans Sodium Crocetinate (TSC) for Treatment of Suspected Stroke | Phase 2 | Interventional | The study was stopped due to lack of meaningful enrollment due to the COVID-19 pandemic. | Actual 6 |
NCT04027270 | Withdrawn | Pelvic Health and Physical Therapy to Improve Lives of Prostate Cancer Patients Undergoing Prostatectomy | N/A | Interventional | Covid | Actual 0 |
NCT04042051 | Terminated | Copanlisib in Combination With T-DM1 in Pretreated Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer | Phase 1 | Interventional | Accrual rate to date was too low to finish the trial in a reasonable timeframe | Actual 2 |
NCT04049487 | Terminated | Impact of Exercise on Diastasis Rectus Abdominus | N/A | Interventional | Covid | Actual 6 |
NCT04063943 | Terminated | Long Term Sidus PMCF | N/A | Interventional | Sponsor has decided there is not a business need for this study and is not required to complete. | Actual 11 |
NCT03512353 | Terminated | A Study of Carfilzomib Plus Dexamethasone in Adults With Relapsed or Refractory Multiple Myeloma at US Community Oncology Centers | Phase 2 | Interventional | Sponsor Decision | Actual 7 |
NCT04212650 | Terminated | Losartan to Improve Hip Microfracture | Phase 1/Phase 2 | Interventional | redesigned trial using another placebo controlled drug | Actual 1 |
NCT04240327 | Suspended | Marker Driven Selection of Patients for Prostate Biopsy and Management | Observational | Temporarily closed to accrual due to pending amendment. | Anticipated 300 | |
NCT04522817 | Withdrawn | CLBS119 for Repair of COVID-19 Induced Pulmonary Damage | Phase 1 | Interventional | Acute COVID-19 treatments have improved significantly leading to decreased use of ventilatory support. This, coupled with approval of a vaccine, has changed the profile/prognosis of patients and led to a lack of patients with long-term hypoxia. | Actual 0 |
NCT04536181 | Withdrawn | Study of Initial Steroid Treatment in Young Children With Nephrotic Syndrome | Phase 3 | Interventional | lack of funding | Actual 0 |
NCT02977286 | Terminated | Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids | Phase 4 | Interventional | Poor enrollment | Actual 12 |
NCT03754166 | Terminated | Feasibility of Constraint-induced Therapy Combined With Visual-spatial Cueing Strategy in Patients With Acute Stroke | N/A | Interventional | Study non feasible following changes in organisation of service | Actual 8 |
NCT03807843 | Suspended | Chikungunya Vaccine Study in Previously Exposed Adults | Phase 2 | Interventional | Further screening, enrollment, and dosing of subjects was suspended due to a clinical stock recovery action. | Anticipated 60 |
NCT03993977 | Withdrawn | ROTEM-guided Transfusion Protocol in Attempt to Reduce Blood Transfusions in Major Oncological Surgery | N/A | Interventional | Due to changes in the surgical technique, no potential subjects anymore | Actual 0 |
NCT04667871 | Withdrawn | Effect of Cataract Hyperemulsification Surgery on Meibomian Gland Morphology and Function | Observational | An six-month follow-up was completed after the treatment | Actual 0 | |
NCT03170115 | Terminated | Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer | Phase 2 | Interventional | Aspirin added to chemoradiotherapy was safe but did not improve response to total neoadjuvant treatment. The study was closed due absence of benefit. | Actual 25 |
NCT03360708 | Suspended | Vaccine Therapy in Treating Patients With Recurrent Glioblastoma | Early Phase 1 | Interventional | protocol design | Anticipated 20 |
NCT03561090 | Terminated | A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors | Phase 3 | Interventional | Parallel IW-3718 Phase III trial did not meet pre-specified criteria. | Actual 495 |
NCT03610581 | Terminated | Safety, Reactogenicity and Immunogenicity of Adenovirus Serotype 26 (Ad26)- and Modified Vaccinia Ankara (MVA)-Vectored Vaccine Components in Otherwise Healthy Women With HPV16 or HPV18 Infection of the Cervix | Phase 1/Phase 2 | Interventional | Low enrolment and increasing COVID restrictions, following an earlier enrolment pause in April made it clear that completion of the study would not be feasible | Actual 9 |
NCT04511975 | Suspended | A Study Evaluating the Safety and Efficacy of IBI188 in Combination With AZA in Subjects With Newly Diagnosed MDS | Phase 1 | Interventional | Clinical hold | Anticipated 32 |
NCT03263390 | Terminated | Modeling the Neurological Basis and Characterizing the Neurological Phenotype of Obesity Using Human Neural Stem Cells | Observational | Study terminated by study partners | Actual 6 | |
NCT03674190 | Withdrawn | A Study Comparing the Outcome of Anterior Lumbar Fusion and Total Lumbar Disc Replacement | N/A | Interventional | Difficult to find patients that accepted the study | Actual 0 |
NCT03280121 | Terminated | Hernia Reduction Prior to Scheduled TIF Completion | N/A | Interventional | Slow enrollment and Covid-19 | Actual 14 |
NCT04673435 | Withdrawn | Permeaderm Versus Homograft for Full-thickness Burns | N/A | Interventional | Protocol was withdrawn and closed by IRB in April, 2018 prior to enrollment of first patient | Actual 0 |
NCT04055168 | Terminated | A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD6615 in Healthy Subjects | Phase 1 | Interventional | It was decided to not run the Japanese cohorts in the study. | Actual 24 |
NCT04324021 | Terminated | Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection. | Phase 2/Phase 3 | Interventional | Standard of care evolved during the timeframe of the study and had critical impact on recruitment. Early termination is not based on safety reasons but because of recruitment issues. Patients ongoing will be completed. Planned LPLV 25Jan2021 | Actual 16 |
NCT04490382 | Withdrawn | Spinal Cord Stimulation (SCS) for Amputees | N/A | Interventional | Funding | Actual 0 |
NCT00470249 | Terminated | Carboplatin and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Breast Cancer | Phase 2 | Interventional | Due to difficulty in recruitment | Actual 5 |
NCT03587831 | Suspended | Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis | N/A | Interventional | Recruitment has been halted until further funding is secured. | Anticipated 60 |
NCT03967587 | Suspended | Evaluation of Intravascular Monitoring of Partial PRessure of Oxygen for Neonatal intensiVE Care Patients | N/A | Interventional | Suspended due to a Device Deficiency, an obstruction at the position under the suture thread. Before resuming the clinical investigation, a protective action must be implemented to avoid the catheter from kinking at the site of the suture. | Anticipated 50 |
NCT04215900 | Suspended | High-Speed Yoga and Executive Function | N/A | Interventional | COVID-19 | Anticipated 90 |
NCT04389229 | Withdrawn | OVSTAR TIL Trial (OVarian Cancer Co-STimulatory Antigen Receptor TIL Trial) | Phase 1/Phase 2 | Interventional | Sponsor decision | Actual 0 |
NCT04531865 | Withdrawn | Randomized Trial Evaluating Mycophenolate Mofetil in Children With Nephrotic Syndrome After Rituximab Treatment | Phase 3 | Interventional | To Whom it may concern, we are writing to terminate the trial due to lack of funding. No participant was enrolled. We are sorry for any inconvenience caused. Please let me know if this is suitable.Thank you and best regards. | Actual 0 |
NCT04577131 | Suspended | Improving Adherence to Home Blood Pressure Monitoring With Pharmacist Support | N/A | Interventional | App has been discontinued. Waiting on IRB approval for an amendment | Anticipated 50 |
NCT04671420 | Withdrawn | Evaluate the Efficacy and Safety of HLX01 Versus Mabthera in Patients With Low Tumour Burden Follicular Lymphoma. | Phase 3 | Interventional | sponsor strategy decision | Actual 0 |
NCT00114712 | Terminated | The Ribavirin Pregnancy Registry | Observational [Patient Registry] | Per the Division of Project Management, Office of Regulatory Operations, Office of Generic Drugs, FDA there is no regulatory requirement to continue this Registry. | Actual 477 | |
NCT00823290 | Terminated | Sorafenib and LBH589 in Hepatocellular Carcinoma (HCC) | Phase 1 | Interventional | Investigator left site | Actual 2 |
NCT01524120 | Withdrawn | Endoscopy and Endomicroscopy for Assessment of Mucosal Healing in Inflammatory Bowel Disease (IBD) | Observational | Actual 0 | ||
NCT02597465 | Withdrawn | A Randomized, Open-Label, Comparative, Parallel-Group, Multicenter Study of SPARC1507 | Phase 3 | Interventional | Sponsor decided not to initiate the study for alternate commercial strategy | Actual 0 |
NCT03519126 | Terminated | Electrostimulation in the Treatment of Idiopathic Overactive Bladder | N/A | Interventional | Due to the covid-19 pandemic | Actual 67 |
NCT03563352 | Withdrawn | Nutritional Preferences and Product Accessibility in Oral Nutritional Supplements in Participants With Breast, Colorectal, Upper Gastrointestinal, or Prostate Cancer | Observational | Zero accrual | Actual 0 | |
NCT03713320 | Terminated | SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides | Phase 2 | Interventional | The study was terminated early for business reasons, and not due to concerns regarding safety or lack of efficacy. | Actual 37 |
NCT03720392 | Terminated | Fecal Microbiota Transplantation (FMT) in Recipients After Allogeneic Hematopoietic Cell Transplantation (HCT) | Phase 2 | Interventional | Terminated due to sponsor decision | Actual 8 |
NCT03868891 | Suspended | Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cleft Palate | N/A | Interventional | All study procedures have been suspended since March 20, 2020 due to Coronavirus Disease 2019. | Anticipated 30 |
NCT03881553 | Terminated | Interventions to Help Infants Recover in the Hospital | N/A | Interventional | Covid halt in March; PI subsequently moved to another Institution | Actual 14 |
NCT03881748 | Suspended | Clinical Trial of Acupuncture for Chemotherapy-Induced Peripheral Neuropathy | N/A | Interventional | Insufficient staff | Anticipated 20 |
NCT04109092 | Withdrawn | A Study of Stimulator of Interferon Genes (STING) Agonist E7766 in Non-muscle Invasive Bladder Cancer (NMIBC) Including Participants Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy, INPUT-102 | Phase 1 | Interventional | There was no enrolment of participants.Unscheduled Clinical Study Closure - Eisai Network Company Decision, November 12, 2020. | Actual 0 |
NCT04369599 | Suspended | Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q Vest for COVID-19 | N/A | Interventional | Enrollment temporarily suspended pending protocol updates. | Anticipated 24 |
NCT04388722 | Withdrawn | Monitoring Noninvasively for Infusion and Transfusion Optimization | N/A | Interventional | Sponsor's decision to withdraw study. | Actual 0 |
NCT04537975 | Withdrawn | C2Rx Hemofiltration Treatment in Severe or Critically Ill Adults With COVID-19 | N/A | Interventional | Withdrawn (Study was withdrawn by Sponsor because of change in regulatory strategy.) | Actual 0 |
NCT03514277 | Terminated | A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief | Phase 4 | Interventional | PI decision to close study early | Actual 19 |
NCT03472755 | Withdrawn | Comparison of Direct Anterior and Posterior Surgical Approaches in Regards to the Patient' Physical Characteristics | N/A | Interventional | difficulty in setting up the study in the investigator site | Actual 0 |
NCT03773172 | Terminated | Study to Evaluate the Effects of MEDI6012 on Apolipoprotein B100 Metabolism | Phase 2 | Interventional | Early termination due to COVID-19 | Actual 7 |
NCT03901079 | Terminated | Trial for A Novel Facilitated Antegrade Steering Technique in Revascularization of Coronary Chronic Total Occlusions | Observational | HGRAC approval letter had expired. The enrollment speed of FAST CTO is much slower than planning and the scientific value becomes limited due to the delayed data readout anticipation. | Actual 20 | |
NCT04194840 | Suspended | Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT | N/A | Interventional | COVID-19 | Anticipated 20 |
NCT04397393 | Terminated | Does Camel Milk Consumption Decrease The Efficacy Of Midazolam For Sedation | Observational | insufficient data | Actual 26 | |
NCT04665310 | Withdrawn | Evaluation of Anti-rejection Drug, Tacrolimus, in African-Americans With Kidney Transplant | Phase 4 | Interventional | Study not started, funding | Actual 0 |
NCT01805037 | Terminated | Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas | Phase 1/Phase 2 | Interventional | Lack of funding | Actual 20 |
NCT02282514 | Terminated | Stem Cell Transplantation for Stiff Person Syndrome (SPS) | Phase 1/Phase 2 | Interventional | Could not predict who would respond, relapse or go into remission | Actual 23 |
NCT02213757 | Terminated | Effect of Vaginal Estrogen on Asymptomatic Microhematuria (AMH) | Phase 4 | Interventional | Low Enrollment | Actual 27 |
NCT04663269 | Terminated | Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy | Phase 4 | Interventional | Drop out from surgeons from 3 to 1. It will take too long to feasibly accrue with only one provider. | Actual 5 |
NCT04668859 | Terminated | Midodrine as Novel Treatment of Post-Cardiopulmonary Bypass Vasoplegic Syndrome | Phase 4 | Interventional | PI relocated | Actual 10 |
NCT02893176 | Withdrawn | Macitentan in the Treatment of Organ Rejection After Lung Transplantation | Phase 4 | Interventional | Actual 0 | |
NCT03715400 | Suspended | Mobile Virtual Positive Experiences for Anhedonia | N/A | Interventional | COVID-19 Restrictions for in-person study procedures | Anticipated 74 |
NCT04309825 | Withdrawn | Transgastrostomal Endoscopies | N/A | Interventional | no IRB approval | Actual 0 |
NCT04433546 | Terminated | Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). | Phase 2 | Interventional | Company no longer pursing indication | Actual 54 |
NCT04137107 | Suspended | Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer | Phase 2/Phase 3 | Interventional | Protocol-specified safety stopping rule | Anticipated 327 |
NCT01842282 | Suspended | Amlexanox for Type 2 Diabetes and Obesity | Phase 2 | Interventional | Funding struggles, may resume recruitment if funding problems resolve | Anticipated 15 |
NCT01906073 | Withdrawn | Nasal Fentanyl for Chronic Cancer Pain | Phase 3 | Interventional | Actual 0 | |
NCT03323190 | Withdrawn | An Educational Intervention to Improve Disease Management Knowledge of Hospitalized Patients With COPD | N/A | Interventional | Withdrawn due to low feasibility. | Actual 0 |
NCT03353896 | Withdrawn | NovoTTF-200A Device in Treating Patients With Newly Diagnosed High Risk Oligodendroglioma | N/A | Interventional | Insufficient accrual | Actual 0 |
NCT03420521 | Terminated | Nivolumab With Ipilimumab in Subjects With Neuroendocrine Tumors | Phase 2 | Interventional | Loss of funding | Actual 9 |
NCT02681809 | Terminated | A Study to Evaluate the Efficacy and Safety of Ocriplasmin in Inducing Total PVD in Subjects With NPDR | Phase 2 | Interventional | Slow recruitment rate | Actual 48 |
NCT03631654 | Withdrawn | Ivabradine in Stage D Heart Failure Patients on Chronic Inotropes | Phase 4 | Interventional | Unable to obtain funding | Actual 0 |
NCT03922477 | Terminated | A Study Evaluating the Safety and Pharmacokinetics of Atezolizumab Administered in Combination With Hu5F9-G4 to Patients With Relapsed and/or Refractory Acute Myeloid Leukemia | Phase 1 | Interventional | F. Hoffmann-La Roche has decided to terminate enrollment and close the study prior to planned due to a lack of continued strategic fit. | Actual 13 |
NCT04077372 | Suspended | Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers | N/A | Interventional | Covid-19 | Anticipated 68 |
NCT04329923 | Terminated | The PATCH Trial (Prevention And Treatment of COVID-19 With Hydroxychloroquine) | Phase 2 | Interventional | Cohort 1: slow accrual Cohort 2: Other studies showed no benefit Cohort 3: Study met pre-specificied futility analysis at planned second interim analysis | Actual 173 |
NCT04603690 | Withdrawn | Study to Investigate the Benefits of Colchicine in Patients With COVID-19 | Phase 3 | Interventional | No funding available | Actual 0 |
NCT02745210 | Terminated | Non-invasive Clinical Imaging of Cerebral Metabolism Following Brain Injury Using 13C Magnetic Resonance Spectroscopy. | N/A | Interventional | The acquisition sequence was incompatible with MRI hardware | Actual 9 |
NCT02598674 | Withdrawn | Severe Sepsis in Children - IMPRESS-C | Observational | Expired IRB | Actual 0 | |
NCT03123783 | Terminated | CD40 Agonistic Antibody APX005M in Combination With Nivolumab | Phase 1/Phase 2 | Interventional | Sponsor business reasons | Actual 400 |
NCT03348735 | Terminated | Localized Neuropathic Pain: Topical Treatment Versus Systemic Treatment | Phase 4 | Interventional | Low inclusion rate | Actual 33 |
NCT03720210 | Terminated | Radiofrequency Ablation for Amiodarone-induced Thyrotoxicosis | N/A | Interventional | Very low enrollment | Actual 1 |
NCT04139382 | Suspended | Using Telemedicine to Improve Early Medical Abortion at Home | N/A | Interventional | Suspended during COVID-19 outbreak, aim to re-start 2021 | Anticipated 1222 |
NCT04198168 | Terminated | The Predictive Performance of Renal Ultrasound on Changes in Renal Clearance | Observational | Due to the COVID-19 situation, it was not feasible to complete the study in our ICU. | Actual 2 | |
NCT00634972 | Terminated | Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity | Phase 4 | Interventional | The study could not be completed as the company producing this product interrupted their supply of this medication | Actual 83 |
NCT01121120 | Terminated | Acceleration of Platelet Recovery Following Autologous Peripheral Blood Stem Cell Transplant (PBSC) in Hodgkin, Non-Hodgkin Lymphoma or Multiple Myeloma Patients | Phase 2 | Interventional | Actual 75 | |
NCT01300611 | Terminated | TXA127 in Enhancement of Engraftment in Adult Double Cord Blood Transplantation | Phase 1 | Interventional | Anticipated 20 | |
NCT04664803 | Terminated | Safety and Efficacy of Cefecin Tab. in Patients With Acute Sinusitis | Phase 4 | Interventional | Actual 284 | |
NCT03537612 | Suspended | Sensorial and Physiological Mechanism-based Assessments of Perioperative Pain | Phase 3 | Interventional | Do to our inability to meet recruitment targets - Sponsor stopped funding. Looking for new sponsor and protocol modifications | Anticipated 150 |
NCT02382588 | Terminated | Comparison of Topical 0.15% Gancyclovir Gel Versus 0.3% Hypromellose Gel for the Treatment of Herpes Zoster Keratitis | Phase 2 | Interventional | There were difficulties meeting the enrollment goal within stipulated time frames. | Actual 7 |
NCT02401074 | Withdrawn | Airway Temperature | Phase 1 | Interventional | Study was withdrawn prior to patient enrollment due to COVID-19, funding termination and lack of eligible study participants. | Actual 0 |
NCT00760929 | Terminated | A Study of the Effect of R1507 in Combination With Tarceva (Erlotinib) on Progression-Free Survival in Patients With Stage IIIb/IV Non-Small Cell Lung Cancer (NSCLC). | Phase 2 | Interventional | The study was terminated due to the termination of the clinical development program. | Actual 171 |
NCT04656808 | Terminated | Guilt Focused Psychological Intervention | N/A | Interventional | COVID-19 | Actual 110 |
NCT02607228 | Terminated | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 (Alobresib) as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer | Phase 1/Phase 2 | Interventional | Actual 31 | |
NCT02803632 | Terminated | Clinical and Actigraphic Profile of Young Patients Admitted for Attempted Suicide | N/A | Interventional | recruitment problem | Actual 98 |
NCT02905279 | Terminated | Spider Phobia Opposite Action Treatment Study | N/A | Interventional | Doctoral student running the study left for internship and did not finish the study | Actual 44 |
NCT03240003 | Suspended | A Novel Computer-Based Therapy for Social Anxiety | N/A | Interventional | funding unavailable | Anticipated 60 |
NCT03794960 | Withdrawn | Diabetes AutoimmunitY Withdrawn in Established Patients (DAY) | Phase 2 | Interventional | Modification to Clinical Development Plan | Actual 0 |
NCT03794973 | Withdrawn | Diabetes Autoimmunity Withdrawn in New Onset Patients (DAWN) | Phase 2 | Interventional | Modification to Clinical Development Plan | Actual 0 |
NCT03993314 | Terminated | Optimizing Anesthesia for Post Partum Tubal Ligations | Phase 2 | Interventional | Lack of recruitment due to COVID-19 pandemic; chloroprocaine shortage | Actual 17 |
NCT04031066 | Withdrawn | Interventional Study to Assess Efficacy and Safety of Velmanase Alfa in Patients With Alpha Mannosidosis | Phase 3 | Interventional | Big delay on study activation (approval procedures by IRBs, hospitals contract negotiation) and on enrolment deadline due to CoViD-19; Placebo stock expires November 2021 and new batch not be available for at least one year | Actual 0 |
NCT04185727 | Terminated | Training Intervention in the Treatment of Anorexia Nervosa | N/A | Interventional | Corona. | Actual 5 |
NCT04186598 | Suspended | Evaluating the Utility of Continuous Positive Airway Pressure in the Treatment of High Altitude Pulmonary Edema | N/A | Interventional | Due to COVID-19 with temporary closure of recruitment sites | Anticipated 264 |
NCT04410354 | Terminated | Study of Merimepodib in Combination With Remdesivir in Adult Patients With Advanced COVID-19 | Phase 2 | Interventional | Failure to meet primary endpoint | Actual 44 |
NCT04437953 | Withdrawn | Avatrombopag for Thrombocytopenia in People With Cancer | Phase 2 | Interventional | Lack of accrual | Actual 0 |
NCT04498598 | Suspended | Structural Modification In Supraglottic Airway Device | N/A | Interventional | The manufacturer of the device has pending modifications to the device. Enrollment will resume once the revised devices are received at the site | Anticipated 100 |
NCT02926521 | Suspended | Assessing Current Peripheral Nerve Block Catheter Fixation and Dressing Strategies: An Equivalence Study | N/A | Interventional | COVID 19 RELATED FACTORS | Anticipated 800 |
NCT03295695 | Withdrawn | PET-CT Imaging Using FDG-labeled Human Erythrocytes in Breast Cancer Patient | Early Phase 1 | Interventional | closure of radiolaboratory | Actual 0 |
NCT03354962 | Terminated | Induction of Immune-mediated aBscOpal Effect thrOugh STEreotactic Radiation Therapy in Metastatic Melanoma Patients Treated by PD-1 + CTLA-4 Inhibitors (BOOSTER MELANOMA) | Phase 1/Phase 2 | Interventional | Slow recruitment rate | Actual 6 |
NCT03543969 | Suspended | Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma | Early Phase 1 | Interventional | pending amendment | Anticipated 20 |
NCT03904199 | Suspended | Prospective Study of Personalized Approach to Inpatient Patients With Hyperglycemia | Phase 4 | Interventional | pending amendment | Anticipated 576 |
NCT03909295 | Terminated | An Open-label Extension Study Evaluating Safety and Tolerability of LCZ696 in Subjects Who Completed PARAGON-HF in Japan. | Phase 3 | Interventional | This study was terminated early because the primary endpoint of PARAGON-HF was not met. | Actual 52 |
NCT04092764 | Suspended | Feasibility Study for Electroacupuncture for Chemotherapy- Induced Peripheral Neuropathy (CIPN) | N/A | Interventional | acupuncturist unavailable | Actual 5 |
NCT00272987 | Terminated | ErbB2 Over-expressing Metastatic Breast Cancer Study Using Paclitaxel, Trastuzumab, and Lapatinib | Phase 3 | Interventional | Enrollment was closed after the open label stage due to poor recruitment rate (randomized stage never opened). | Actual 63 |
NCT01714817 | Terminated | Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis | Phase 3 | Interventional | Inability to meet protocol objectives. | Actual 695 |
NCT00701077 | Terminated | DAPERB 3,4-DiAminoPyridine and Electrophysiological Response in Brugada Syndrome | Phase 3 | Interventional | recruitments issues | Actual 5 |
NCT01101581 | Withdrawn | Study of Veltuzumab and 90Y-Epratuzumab in Relapsed/Refractory, Aggressive NHL | Phase 1/Phase 2 | Interventional | No subjects enrolled | Actual 0 |
NCT01510561 | Withdrawn | A Study of Fractionated 90Y-hPAM4 Plus Gemcitabine in Pancreatic Cancer Patients Receiving at Least 2 Prior Therapies. | Phase 1 | Interventional | no subjects enrolled | Actual 0 |
NCT01915472 | Withdrawn | A Phase II Study of IMMU 130 in Patients With Metastatic Colorectal Cancer | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT03068130 | Terminated | Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER | Phase 3 | Interventional | The company determined that continued exposure of these high-risk PH patients to clinic or in-person visits during the COVID pandemic presented an unacceptable risk. | Actual 261 |
NCT03452202 | Suspended | Using tDCS in Speech-based Stroke Rehabilitation | N/A | Interventional | COVID-19: protocol requires a large number (20+) of specifically timed visits. Because a mistimed visit would disqualify a participant, we have suspended until travel and data collection can be assured. | Anticipated 12 |
NCT03563911 | Withdrawn | Brief Mindfulness and Nutrition-Based Interventions for Chronic Pain: Strategies to Ease Pain | N/A | Interventional | COVID pandemic | Actual 0 |
NCT03691415 | Terminated | Evaluation of the Safety and Effectiveness of BELKYRA® Inj. for the Treatment of Patients With Submental Fullness Due to Submental Fat: A Postmarketing Surveillance Study in Korea | Observational | Study discontinued due to business decisions. | Actual 71 | |
NCT03844646 | Suspended | Continuous Glucose Monitoring to Aid Weight Loss in Prediabetes | N/A | Interventional | COVID-19 | Anticipated 20 |
NCT03996252 | Terminated | Combination Topical Therapy for Treatment of Scalp Actinic Keratoses | Early Phase 1 | Interventional | The study team was not able to start the study and they never completed the IRB submission, so the study was terminated. | Actual 15 |
NCT04125745 | Terminated | Oral CXA-10 in Pulmonary Arterial Hypertension | Phase 2 | Interventional | negative study outcome from Complexa's multicenter clinical trial; no safety concerns | Actual 2 |
NCT04245852 | Terminated | Does a Video-based Education Tool Related to Strengthening Result in Different Functional Outcomes Compared to Traditional Physical Therapy Education for Patients? | N/A | Interventional | COVID pandemic disrupted subject recruitment and primary investigator no longer with our university; no additional interest in continuing the study. | Actual 5 |
NCT04287179 | Withdrawn | SUSTAIN SWITCH: A Research Study to Compare Two Dose Schedules of Semaglutide Taken Once Weekly in People With Type 2 Diabetes | Phase 3 | Interventional | COVID19 impact on this trial was evaluated and a delay of at least 6-9 months was expected. In parallel, the development of a new type of pen injector, which was an important part of the trial, was ceased and thus this trial was cancelled. | Actual 0 |
NCT04355676 | Withdrawn | Evaluation of Activity and Safety of Two Regimens of Low Dose Oral Selinexor in Participants With Moderate or Severe COVID-19 | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT04394104 | Terminated | COVID-19 Wellness Survey | Observational | Study has concluded. | Actual 593 | |
NCT04558216 | Suspended | Evaluation of Effect of Rifampin on the Pharmacokinetics of Vonoprazan in Healthy Participants | Phase 1 | Interventional | Currently suspended due to ongoing FDA evaluation of rifampin products | Anticipated 16 |
NCT02663934 | Terminated | Exercise Training to Improve Brain Health in Older HIV+ Individuals | N/A | Interventional | COVID-19 Risk | Actual 75 |
NCT02776709 | Withdrawn | Feasibility of a Single-operator Peroral Cholangiopancreatioscopy System (SpyGlass) | Observational [Patient Registry] | Actual 0 | ||
NCT03024424 | Suspended | Value of Genetic Counseling and Testing for Patients Who Would Like to Know More About Their Personal Risk of AMD | N/A | Interventional | Anticipated 200 | |
NCT03058146 | Terminated | Independent Walking for Brain Health | N/A | Interventional | COVID-19 | Actual 55 |
NCT03257332 | Withdrawn | Determining Early Development of Faecal Incontinence and Anorectal Muscle Function After Surgery for Rectal Cancer. | Observational [Patient Registry] | Not possible to include participants | Actual 0 | |
NCT03660657 | Suspended | Ozone Therapy in Refractory Ischemic Heart Disease. | Phase 2/Phase 3 | Interventional | Very low recruitment. During COVID-19 pandemic these are patients of high risk. | Anticipated 18 |
NCT03800069 | Terminated | Validation of Point of Care Liver Function Tests | Observational | scheduling complexities | Actual 68 | |
NCT04066192 | Suspended | Brexpiprazole in Alcohol Use Disorder | Phase 2 | Interventional | Recruitment temporarily paused due to Level Red COVID numbers and restrictions. | Anticipated 250 |
NCT02576977 | Terminated | Study of Pomalidomide and Low Dose Dexamethasone With or Without Pembrolizumab (MK-3475) in Refractory or Relapsed and Refractory Multiple Myeloma (rrMM) (MK-3475-183/KEYNOTE-183) | Phase 3 | Interventional | The study was terminated early due to business reasons | Actual 251 |
NCT04069910 | Terminated | Stereotactic Radiation Therapy Before Surgery for the Treatment of Resectable Brain Metastases | N/A | Interventional | slow enrollment | Actual 1 |
NCT02579863 | Terminated | Study of Lenalidomide and Dexamethasone With or Without Pembrolizumab (MK-3475) in Participants With Newly Diagnosed Treatment Naive Multiple Myeloma (MK-3475-185/KEYNOTE-185) | Phase 3 | Interventional | The study was terminated early due to business reasons | Actual 310 |
NCT04253457 | Suspended | The SToICAL Study - The Soft Tissue Injection of Corticosteroid And Local Anaesthetic Study | Phase 3 | Interventional | COVID-19 | Anticipated 100 |
NCT04338997 | Withdrawn | PK Study in Patients With Parkinson's Disease With IZD174 | Phase 1 | Interventional | Strategic decision by Sponsor | Actual 0 |
NCT04659694 | Withdrawn | Effect of an Intervention on Health in Older Care Home Residents | N/A | Interventional | Withdrawal of PhD | Actual 0 |
NCT01861028 | Terminated | Study Comparing Fit of the iTotal Versus Standard Total Knee Implants | Observational | Not enough patient volume to continue the study. | Actual 44 | |
NCT02046135 | Terminated | Sodium Bicarbonate to Prevent Acute Kidney Injury in Children Undergoing Cardiac Surgery | Phase 2 | Interventional | Statistical analysis at interim analysis determined futility in continuing. | Actual 51 |
NCT03041116 | Terminated | Efficacy and Safety Study of Fosmetpantotenate (RE-024) in PKAN Participants | Phase 3 | Interventional | The study was terminated since fosmetpantotenate did not show statistically significant effects or clinical benefits during the double-blind period. | Actual 84 |
NCT04151225 | Withdrawn | Study to Evaluate Safety, Tolerability and Efficacy of GSK2330811 in Crohn's Disease | Phase 2 | Interventional | Internal sponsor decision to terminate project in Crohn's disease due to potential narrow therapeutic window. No subjects were enrolled | Actual 0 |
NCT04368000 | Terminated | Prone Positioning in Awake Patients With COVID-19 Requiring Hospitalization | N/A | Interventional | Study was terminated due to lack of adherence to the protocol in the intervention arm. | Actual 30 |
NCT04460729 | Withdrawn | A Phase II, Open-Label, Multicenter Study of Capmatinib in Subjects With MET Exon 14 Skipping Mutation Positive, Advanced, NSCLC With Brain Metastases | Phase 2 | Interventional | company decision | Actual 0 |
NCT01268059 | Terminated | A Study of Carboplatin and Paclitaxel With or Without MEDI-575 in Untreated, Advanced Non-Small Cell Lung Cancer | Phase 1/Phase 2 | Interventional | In conjunction with the overall risk-benefit assessment, study was terminated prematurely due to safety concerns. | Actual 99 |
NCT04497948 | Terminated | Acalabrutinib Study With Best Supportive Care in Participants Hospitalized With COVID-19 | Phase 1 | Interventional | Data from the CALAVI Phase II trials for Acalabrutinib in patients hospitalized with COVID-19 did not meet their primary efficacy endpoints. Based on this higher management made the decision to prematurely terminate the D822FC00005 PK study. | Actual 8 |
NCT02693444 | Withdrawn | Comparison of Strength and Constant Score Pre- and Post-Subacromial Injection for Full Thickness Rotator Cuff Tears | N/A | Interventional | Low pool of subjects | Actual 0 |
NCT03145779 | Withdrawn | Evaluation of Phenotypic Variability in Fabry Disease | Observational | Funding | Actual 0 | |
NCT03353610 | Terminated | The PSVT Place Registry.Paroxysmal Supraventricular Tachycardia (PSVT) Registry. | Observational | Termination due to lack of adequate enrollment | Actual 354 | |
NCT03666429 | Withdrawn | Effectiveness of the NoseFrida Compared With Bulb Suction at Relieving Objective Signs of Nasal Obstruction and Reducing Return Visits in Pediatric Patients Presenting to the Emergency Department | N/A | Interventional | PI left institution | Actual 0 |
NCT03785392 | Terminated | Out of Plane Approach for Interscalene | N/A | Interventional | Primary investigator left the Institution | Actual 30 |
NCT03843320 | Suspended | Impact of SAVR and TAVR on Patient's Activity and Mobility | Observational | Reassessing study feasibility | Anticipated 340 | |
NCT02862535 | Terminated | Study to Evaluate the Safety and Tolerability of Andecaliximab as Monotherapy and in Combination With Anti-Cancer Agents in Japanese Participants With Gastric or Gastroesophageal Junction Adenocarcinoma | Phase 1 | Interventional | Study was terminated due to sponsor's decision to not pursue further development of andecaliximab in oncology | Actual 36 |
NCT03137693 | Terminated | Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer | N/A | Interventional | no responders/lack of efficacy | Actual 20 |
NCT00023868 | Terminated | Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655) | Phase 3 | Interventional | redesign | 0 |
NCT01002209 | Withdrawn | Postoperative Hyperbaric Oxygen Treatments to Reduce Complications in Diabetic Patients Undergoing Vascular Surgery | Phase 2/Phase 3 | Interventional | Changes in the organisation | Actual 0 |
NCT03686423 | Suspended | Reversing Diabetic Peripheral Neuropathy Through Exercise | Observational | patient cohort consists of diabetic patients, which is a co-risk factor for covid-19 | Anticipated 40 | |
NCT03805464 | Suspended | Walking Gait Biomechanics Following Knee Joint Effusion | N/A | Interventional | This study is suspended secondary to staffing/PI availability until February 2021. | Anticipated 25 |
NCT03809494 | Terminated | HemaTrate™ in the Treatment of Critical Limb Ischemia | N/A | Interventional | The study has stopped early due to enrollment challenges related largely to the current pandemic | Actual 2 |
NCT04004416 | Suspended | Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis | Phase 4 | Interventional | Enrollment and interactions/interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. | Anticipated 232 |
NCT04010461 | Suspended | Theta Burst Transcranial Magnetic Stimulation of Fronto-parietal Networks: Modulation by Mental State | N/A | Interventional | Enrollment and interactions/interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. | Anticipated 48 |
NCT04052204 | Terminated | Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors | Phase 2 | Interventional | The recruitment of new subjects has been stopped with no intention of restarting the study before reaching the protocol specified End of Trial. | Actual 3 |
NCT04156204 | Terminated | Immunosuppressant Medication Dosed Daily After Kidney Transplant | Early Phase 1 | Interventional | Discontinuation of study due to site staffing and resources available to conduct the study | Actual 1 |
NCT01620216 | Terminated | Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia | Phase 2 | Interventional | Unable to recruit enough eligible subjects | Actual 13 |
NCT03904342 | Withdrawn | Sophie Pilot Implementation and Assessment | N/A | Interventional | This study was not conducted due to concerns about collaboration with an outside vendor for the control condition. | Actual 0 |
NCT04014569 | Terminated | Determination of Automated Multiple Insulin Dose Injections Settings Using the MDI/SMBG Advisor for Patients With Type 1 Diabetes -Data Collection, Observational & Proof of Concept Study | N/A | Interventional | Investigators decision | Actual 6 |
NCT02940223 | Terminated | Ethyl Icosapentate and Physical Activity in Treating Fatigue in Patients With Advanced Cancer | Phase 2 | Interventional | PI is requesting termination (closure) of this study. | Actual 2 |
NCT03990597 | Withdrawn | StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord | Phase 1 | Interventional | Per PI | Actual 0 |
NCT00626197 | Terminated | A Study to Evaluate Ocrelizumab in Patients With Nephritis Due to Systemic Lupus Erythematosus (BELONG) | Phase 3 | Interventional | Study was terminated due to an imbalance of serious and opportunistic infections in the ocrelizumab treated patients versus the placebo arm. | Actual 381 |
NCT02704403 | Terminated | Phase 3 Study to Evaluate the Efficacy and Safety of Elafibranor Versus Placebo in Patients With Nonalcoholic Steatohepatitis (NASH) | Phase 3 | Interventional | Study did not meet the predefined primary surrogate efficacy endpoint, no safety issues identified | Actual 2157 |
NCT02993094 | Terminated | Ixazomib (MLN9708) in Combination With Carboplatin in Pretreated Women With Advanced Triple Negative Breast Cancer | Phase 1/Phase 2 | Interventional | Due to slow recruitment, the study had to be terminated prematurely. | Actual 31 |
NCT03040453 | Withdrawn | Immunological Response After Ablative Therapy in the Liver | N/A | Interventional | poor recruitment | Actual 0 |
NCT03676543 | Suspended | Mutual Interactions Between Absence Epilepsy Seizures and the Integration of Sensory Stimuli | N/A | Interventional | we arrived to the end of the inclusion and only 1 patient was recruited. We will submit an amendement | Anticipated 20 |
NCT03873662 | Terminated | Biochemical Makers for Outcome After Pediatric out-of Hospital Cardiac Arrest | Observational | Low inclusion rate | Actual 4 | |
NCT04167345 | Terminated | Evaluation of the Efficacy and Safety of VX-814 in Subjects With the PiZZ Genotype | Phase 2 | Interventional | at Sponsor's discretion | Actual 48 |
NCT04246034 | Withdrawn | Microvascular Breast Reconstruction With Lymph Node Transfer | N/A | Interventional | surgery considered elective and cant be performed within corona restrictions | Actual 0 |
NCT01602302 | Terminated | Ultrasound and Withdrawal of Biological DMARDs in Rheumatoid Arthritis | Phase 4 | Interventional | low recruitment | Actual 40 |
NCT03301701 | Withdrawn | Feasibility Trial in Men With Hormone Sensitive Oligometastatic Prostate Cancer | N/A | Interventional | Lack of accruals | Actual 0 |
NCT02452983 | Terminated | Sertraline in Treatment of Low-Risk Myelodysplastic Syndrome | Phase 1 | Interventional | This protocol is closed to further enrollment due to lack of study progress. | Actual 14 |
NCT02838030 | Suspended | Efficacy of Aspirin and L-arginine in High Risk Preeclamptic | Phase 2 | Interventional | COVID-19 pandemic | Anticipated 82 |
NCT03397446 | Terminated | Lisdexamfetamine for Adults With Bulimia Nervosa | Phase 2 | Interventional | Loss of resources due to COVID-19 resulted in insufficient funds to complete the trial as planned. However, sufficient data was collected to fulfill the aims of the trial. Discontinuation is not related to the drug, its use, or adverse events. | Actual 23 |
NCT03482466 | Terminated | Neurofeedback for PTSD | N/A | Interventional | Covid-19 | Actual 8 |
NCT04148742 | Suspended | Assessing an Oral Bruton Tyrosine Kinase Inhibitor, DZD9008 in Patients Who Have Non-Hodgkin B-cell Lymphoma (WU-KONG3) | Phase 1/Phase 2 | Interventional | Clinical development strategy adjustment, non-safety reason | Anticipated 120 |
NCT00678002 | Terminated | Quality of Life in Pediatric Transplant Patients | Observational | Poor enrollment | Actual 57 | |
NCT04072874 | Suspended | Evaluation of the Safety and Clinical Activity of Curaleish in the Topical Treatment of Cutaneous Leishmaniasis. | Phase 1/Phase 2 | Interventional | Tthe study is in the approval phase by local regulatory authorities | Anticipated 50 |
NCT04273022 | Suspended | Effect of Exercise on Biomarkers in SCT | N/A | Interventional | Due to the Covid-19 pandemic, Saint Louis University suspended human research studies that did not meet specific criteria, which this study did not meet. | Anticipated 20 |
NCT02692768 | Suspended | The Effect of Music Therapy Intervention on Pain and Anxiety in Adult Patients Undergoing Total Shoulder Arthroplasty | N/A | Interventional | as of 11/24/2020 indefinitely due to COVID-19 | Anticipated 115 |
NCT03309098 | Withdrawn | Agreement Between Clinician and Instrumented Laxity Assessment | Observational | IRB's initial review of this study was not completed and study was withdrawn | Actual 0 | |
NCT03799380 | Suspended | DRIHNC - Dehydration Reduction in Head & Neck Cancer | N/A | Interventional | Interim analysis | Anticipated 155 |
NCT03880123 | Withdrawn | Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma | Phase 1 | Interventional | Study will not proceed, no participants enrolled. | Actual 0 |
NCT04139304 | Suspended | A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma | Early Phase 1 | Interventional | Study contract changes | Anticipated 15 |
NCT04140669 | Terminated | Automated Myocardial Performance Index Using Samsung HERA W10 | Observational | Sponsor support and funding was terminated due to pandemic | Actual 7 | |
NCT04258358 | Suspended | Evaluating the Community Areas of Sustainable Care and Dementia Excellence Model of Care | N/A | Interventional | COVID-19 Interruption | Anticipated 250 |
NCT04362124 | Withdrawn | Performance Evaluation of BCG Vaccination in Healthcare Personnel to Reduce the Severity of COVID-19 Infection. | Phase 3 | Interventional | Study was stopped because Principal Investigator did not obtain sponsorship to carry it out | Actual 0 |
NCT01225341 | Terminated | Botulinum Toxin A for Herpes Labialis | N/A | Interventional | Too many patients withdrew/lost to follow up | Actual 20 |
NCT03407482 | Terminated | An Extension Study of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus | Phase 2 | Interventional | The study was ended early due to the lack of efficacy seen in the parent study GA30044. | Actual 160 |
NCT00011492 | Terminated | Patient Evaluation for Head and Neck Surgery Branch Studies | Observational | Closed by Sponsor/Data Safety monitoring Board/IRB | Actual 62 | |
NCT01629095 | Terminated | Genetic Studies of Non-Alcoholic Fatty Liver Disease | Observational | Slow/insufficient accrual | Actual 17 | |
NCT03849079 | Terminated | Validation of the HYPONUT Product | N/A | Interventional | All prick tests are positive | Actual 6 |
NCT01683214 | Terminated | Brain Network Activation Analysis to Diagnose/Assess Treatment of Unipolar Major Depression and Bipolar I Depression | Observational | Actual 30 | ||
NCT03538795 | Terminated | Brain Stimulation and Rehabilitation for Adults With Chronic, Severe Arm Motor Impairment After Stroke | N/A | Interventional | Ran out of funds | Actual 3 |
NCT01433198 | Withdrawn | Aquatic Training in Patients With Severe Scarring | N/A | Interventional | finances and feasibility | Actual 0 |
NCT01522716 | Terminated | Mesenchymal Stromal Cells as Treatment of Chronic Graft-versus-host Disease | Phase 1 | Interventional | New requirements for study approval with the Swedish Medical Products Agency | Actual 11 |
NCT02311296 | Withdrawn | Reduced Ventilator-Free Days and Bacterial Colonization of Sub-Glottic Secretions | Observational | Study registered to wrong sponsor. | Actual 0 | |
NCT02435095 | Terminated | Antipsychotic Induced Structural and Functional Brain Changes | Phase 4 | Interventional | slow patient recruitment, low patient-commpliance, high dropout rates, | Actual 174 |
NCT02747784 | Terminated | Evaluation to Assess Cognitive Training for the Prevention of Post-operative Cognitive Decline | N/A | Interventional | Lack of recruitment | Actual 19 |
NCT02878694 | Terminated | Treatment of Ptosis to Muscular Dystrophy Oculopharyngeal by Myoblast Autologous Graft | Phase 2/Phase 3 | Interventional | insufficient recruitment | Actual 1 |
NCT03395652 | Withdrawn | Maternal Physical Activity and Pregnancy Outcome | Observational | technical problems | Actual 0 | |
NCT03409757 | Terminated | Velphoro and Impact on the Oral Cavity and Gut Microbiome | Observational | Insufficient Patient Recruitment | Actual 22 | |
NCT03875313 | Terminated | Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors | Phase 1/Phase 2 | Interventional | Slow Enrollment | Actual 33 |
NCT03928834 | Withdrawn | Sustainable Adherence and Prevention of HIV Drug Resistance in Adolescents | N/A | Interventional | There was a delay in getting protocol approvals and hence the study would not be completed in time. | Actual 0 |
NCT04195373 | Withdrawn | A Safety Study of TMV-018 in Patients With Tumors of the Gastrointestinal Tract | Phase 1 | Interventional | Study not started, no subjects recruited. | Actual 0 |
NCT02572570 | Terminated | Clinical Investigation of a New Bulk Fill Composite Resin in the Restoration of Posterior Teeth | N/A | Interventional | Attrition rate complicated by COVID-19 led to termination. | Actual 27 |
NCT01891643 | Terminated | PH III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Previously Untreated Multiple Myeloma (ELO 1 Substudy) | Phase 3 | Interventional | Insufficient enrollment | Actual 29 |
NCT02320292 | Suspended | Rituximab With or Without Yttrium Y-90 Ibritumomab Tiuxetan in Treating Patients With Untreated Follicular Lymphoma | Phase 3 | Interventional | Anticipated 128 | |
NCT02718196 | Withdrawn | Testing and Development of a Sleep Training Mobile Health Application | N/A | Interventional | App stopped development before minimum viable product created | Actual 0 |
NCT03592784 | Terminated | Food Order Intervention for Gestational Diabetes | N/A | Interventional | Lack of enrollment during Covid pandemic, however sufficient data gathered for assessment of primary outcome | Actual 28 |
NCT03159598 | Withdrawn | Drain-Less Abdominally Based Breast Reconstruction Using Lysine-Derived Urethane Adhesive | N/A | Interventional | PI left institution, never submitted to IRB | Actual 0 |
NCT03308734 | Withdrawn | Effects of 6 Week Reduced Exertion High Intensity Interval Training Protocol in Patients With Prostate Cancer | N/A | Interventional | Lack of resource from collaborating organisation | Actual 0 |
NCT03341676 | Suspended | Spectroscopic and Diffusion Weighted Analysis of the Effects of Dexamethasone on High Altitude Cerebral Oedema (HACE) | Phase 1 | Interventional | COVID | Anticipated 30 |
NCT03352024 | Withdrawn | Impact of Hypno-analgesia on Pain During a Lumbar Puncture for Diagnosis of Alzheimer's Disease | N/A | Interventional | internal organizational problem and dysfunction of study material | Actual 0 |
NCT03361319 | Withdrawn | Combination Nab-paclitaxel (N-P) and Nintedanib or N-P and Placebo in Relapsed NSCLC Adenocarcinoma | Phase 1/Phase 2 | Interventional | Withdrawal of financial support from funder | Actual 0 |
NCT03400748 | Terminated | ANET Electrosurgery Applicator Pilot Evaluation Study | N/A | Interventional | business reason | Actual 6 |
NCT03684642 | Terminated | Efficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin | Phase 3 | Interventional | Sponsor decision to cancel TRIAL, not related to safety concern | Actual 909 |
NCT04117438 | Withdrawn | Tell us Your Food Story | Observational | Due to COVID-19 pandemic, we will not be pursuing this study | Actual 0 | |
NCT04414904 | Withdrawn | Determining the Reproductive Health of Men Post-COVID-19 Infection | Observational | Unable to obtain approval | Actual 0 | |
NCT02951156 | Terminated | Avelumab In Combination Regimens That Include An Immune Agonist, Epigenetic Modulator, CD20 Antagonist and/or Conventional Chemotherapy in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL) | Phase 3 | Interventional | Study was terminated due to closure of study arms following futility analysis and difficulty in enrolling participants due to evolving treatment landscape | Actual 29 |
NCT03363776 | Terminated | An Investigational Immuno-Therapy Study of Experimental Medication BMS-986277 Given Alone and in Combination With Nivolumab in Epithelial Cancers | Phase 1/Phase 2 | Interventional | Business objectives have changed | Actual 10 |
NCT01661387 | Terminated | A European Post-Authorisation Observational Study (Registry) of Patients With Chronic Adrenal Insufficiency (AI) | Observational | Takeda submitted 900 patient years Interim Analysis to PRAC and requested study to be closed since primary objective had been fulfilled. PRAC agreed and on 17Sep2020 approved closure of EU-AIR Registry. Takeda announced study closure on 31Oct2020. | Actual 3258 | |
NCT02131376 | Terminated | Investigating a Novel Modifiable Factor Affecting Renal Function After Partial Nephrectomy: Cortical Renorrhaphy | N/A | Interventional | slow accrual, interim analysis showed no statistical significance | Actual 26 |
NCT02154230 | Suspended | Sulphate-bicarbonate-calcium Water, Body Weight and Gut Microbiota | N/A | Interventional | failure to enroll | Anticipated 44 |
NCT02420795 | Terminated | Akt/ERK Inhibitor ONC201 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma | Phase 1/Phase 2 | Interventional | Per PI Request | Actual 16 |
NCT02951572 | Terminated | Non-invasive Ventilation and Physical Activity | N/A | Interventional | Recruitment problem | Actual 8 |
NCT03014258 | Suspended | A Systems Biology Approach to Malaria Immunity | Phase 1 | Interventional | Study is paused due to COVID-19. | Anticipated 34 |
NCT03341273 | Terminated | Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin Level | N/A | Interventional | Due to covid | Actual 514 |
NCT03640338 | Withdrawn | The Efficacy of Continuous Cold-Therapy on Postoperative Pain and Narcotics Use Following Spinal Fusion | N/A | Interventional | Limiting funding sources forced us to withdraw the study. | Actual 0 |
NCT03917719 | Terminated | An Open-Label Extension Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy | Phase 3 | Interventional | The Phase 3 PolarisDMD trial did not meet the primary endpoint. As a result, activities related to the development of edasalonexent have stopped including the CAT-1004-302 Open-Label Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy | Actual 130 |
NCT03956550 | Terminated | A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee | Phase 2 | Interventional | Regeneron has discontinued further clinical development of REGN5069, an antibody to GFRα3, which was previously being studied in osteoarthritis pain of the knee | Actual 259 |
NCT04320524 | Withdrawn | TARA Working Prototype [Version 2]: Feasibility Study | N/A | Interventional | Due to Covid, the study could not be initiated as planned. | Actual 0 |
NCT04363853 | Suspended | Tocilizumab Treatment in Patients With COVID-19 | Phase 2 | Interventional | Pending regulatory issues by Mexico´s health agency (CCINSHAE). Agency has requested further evidence for efficacy, therefore it was suggested that the study be temporarily suspended. | Anticipated 200 |
NCT04371640 | Suspended | Sirolimus in COVID-19 Phase 1 | Phase 1 | Interventional | Study population not regularly admitted to hospital | Anticipated 40 |
NCT04386278 | Terminated | OrthoPulse Gen 2 Initial Device Evaluation and Assessment of Clinical Effectiveness (CA) | N/A | Interventional | Study stopped because slow enrolment. | Actual 56 |
NCT04566536 | Suspended | NoL Monitor Performances of Nociceptive and Non-nociceptive Stimuli Discrimination During Robotic Surgery | Observational | "Owing to the Covid-19 epidemics and in the application of guidelines, inclusions have been suspended in the ROBOTNOL research on November 2nd 2020 for an undetermined period of time." | Anticipated 75 | |
NCT04645264 | Terminated | Effect of Catheter on Postoperative Urinary Retention | N/A | Interventional | PI initiated closure due to limited clinical resources and lack of participation. | Actual 7 |
NCT01383044 | Terminated | Banding Ligation With Carvedilol Versus Carvedilol for the Prevention of First Bleeding | Phase 4 | Interventional | slow enrollment | Actual 65 |
NCT02633124 | Terminated | Preventing Catheter-related Bacteremia When Administering Injectable Medications in Premature Infants. | N/A | Interventional | Actual 87 | |
NCT02920710 | Withdrawn | ACTHAR Therapy for Central Nervous System Sarcoidosis | Phase 4 | Interventional | Difficulty with recruitment | Actual 0 |
NCT03910452 | Suspended | Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide | Early Phase 1 | Interventional | On hold to reviewed data to determine how best to proceed as the patient's transplant course was complicated by engraftment syndrome and other conditions. | Actual 1 |
NCT04638114 | Withdrawn | Mini- Open Direct-anterior Approach vs Hip Arthroscopy for Treatment of Femoroacetabular Impingement. | N/A | Interventional | Investigator is no longer employed in study site | Actual 0 |
NCT03553550 | Terminated | Role of Circulating Tumor DNA (ctDNA) From LIquid Biopsy in Early Stage NSCLC Resected Lung Tumor Investigation | Observational | Enrollment futility | Actual 38 | |
NCT04209621 | Suspended | Duvelisib for Ibrutinib-Resistant Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Interventional | On September 24, 2020 due to unexpected sudden death on study. | Actual 3 |
NCT01097239 | Withdrawn | Examining the Role of Transrectal High Intensity Focused Ultrasound (HIFU) in Rectal Pelvic Cancer | Phase 1/Phase 2 | Interventional | Failure to recruit. | Actual 0 |
NCT01190241 | Terminated | Targeted Therapy Selection Based on Tumor Tissue Kinase Activity Profiles for Patients With Advanced Solid Malignancies, an Exploratory Study | N/A | Interventional | Actual 45 | |
NCT01691976 | Withdrawn | Mild Cognitive Impairment in Men Following Androgen Deprivation | N/A | Interventional | No one recruited due to resource limitations. Issues with how complicated the study could be for patients so the study was later modified and turned into a different study. | Actual 0 |
NCT02070887 | Withdrawn | Inhibiting COMT in Parkinson's Disease | Observational | Actual 0 | ||
NCT03063840 | Withdrawn | Microwave Ablation for the Treatment of Malignant Liver Tumors Closed to Intrahepatic Vessels | N/A | Interventional | NO participants enrolled | Actual 0 |
NCT03325101 | Suspended | Dendritic Cell Therapy After Cryosurgery in Combination With Pembrolizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Remove by Surgery | Phase 1/Phase 2 | Interventional | pending protocol/funding review | Anticipated 39 |
NCT03327272 | Withdrawn | Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion | Phase 3 | Interventional | Did not enroll, PI decided not to proceed. | Actual 0 |
NCT03416816 | Terminated | A Study of DSP-0337 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic Profile | Phase 1 | Interventional | Alternate development strategy | Actual 23 |
NCT03615495 | Suspended | Flourish™ Pediatric Esophageal Atresia | Observational [Patient Registry] | Study plan amendment | Anticipated 20 | |
NCT03901976 | Terminated | ZeroFall - Reliability Testing of Optical Sensor to Detect Bed Exit for Patients in Hospital | N/A | Interventional | Not enough resources in place; COVID-19 pandemic impedes working on the project and travelling within the EU | Actual 14 |
NCT03966547 | Withdrawn | Changes in Cerebral Blood Flow (CBF) in Prone and Sitting Position Before and After GSP-block and Before and After Epidural Blood-patch: A Substudy of NCT03652714 | N/A | Interventional | Main study concluded before enrollment | Actual 0 |
NCT04267913 | Withdrawn | Testing of TAK228 (MLN0128, Sapanisertib) Plus Docetaxel to the Usual Standard of Care for Advanced Squamous Cell Lung Cancer (A Lung-MAP Treatment Trial) | Phase 2 | Interventional | The pharmaceutical company sold the compound and pulled out. | Actual 0 |
NCT04365231 | Withdrawn | Hydroxychloroquine Azithromycin COVID-19 Pregnancy Trial | Phase 3 | Interventional | no authorization obtained | Actual 0 |
NCT04418752 | Withdrawn | Narrative Exposure Therapy for Adults With Intellectual Disability | N/A | Interventional | The study is no longer feasible due to the restrictions placed on access to potential participants during the COVID-19 pandemic. | Actual 0 |
NCT04563559 | Withdrawn | PREFERENTIAL Study | Phase 2/Phase 3 | Interventional | PI decided not to open study | Actual 0 |
NCT03409237 | Withdrawn | Coagulation Activation by Hyperosmolar Agents in Intracranial Hypertension | Observational | No participant enrolled. The human resources to perform the study also due to the COBID emegency | Actual 0 | |
NCT03422757 | Terminated | Safety and Efficacy of Adaptive DBS Vs Conventional DBS in Patients With Parkinson's Disease | N/A | Interventional | Company strategic decision | Actual 6 |
NCT03837457 | Terminated | PRISM: Efficacy and Safety of Cobomarsen (MRG-106) in Subjects With Mycosis Fungoides Who Have Completed the SOLAR Study | Phase 2 | Interventional | Study no longer needed because eligible subjects may receive treatment with cobomarsen in a crossover arm of the SOLAR clinical trial (NCT03713320) | Actual 8 |
NCT03949673 | Terminated | Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and Hip | Phase 2 | Interventional | Lack of enrollment | Actual 23 |
NCT04009486 | Withdrawn | Whole Body Vibration and the Brain in OSA | N/A | Interventional | Not approved for funding | Actual 0 |
NCT04178616 | Terminated | Assessment of the Prevalence of Olfactory Disorders in Systemic Scleroderma | N/A | Interventional | Following the COVID-related health crisis, nasofibroscopic sampling could no longer be carried out | Actual 59 |
NCT04304339 | Suspended | Hypercapnic Acute Respiratory Failure in the ICU : the YETI Study | Observational | Covid19 pandemia | Anticipated 500 | |
NCT04343001 | Withdrawn | Coronavirus Response - Active Support for Hospitalised Covid-19 Patients | Phase 3 | Interventional | Grant not obtained | Actual 0 |
NCT04429464 | Withdrawn | AcQBlate Force Confirmatory Study for Atrial Arrhythmias (AcQBlate Force-PRA) | N/A | Interventional | Due to restrictions related to COVID the sponsor has decided not to move forward with this study | Actual 0 |
NCT02831933 | Terminated | Trial of Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma and Uveal Melanoma | Phase 2 | Interventional | Lack of funding | Actual 13 |
NCT04017624 | Withdrawn | Fresh Truck Pilot to Reduce Food Insecurity in a Medicaid ACO | N/A | Interventional | The COVID-19 pandemic impacted study methods. Therefore, the study team opted not to conduct this study as written. The study never started and no participants were enrolled. | Actual 0 |
NCT04044170 | Terminated | Poziotinib in Patients With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation | Phase 2 | Interventional | Study termination by the Sponsor | Actual 5 |
NCT04098419 | Terminated | Evaluation of a Two-tiered Cross-age Teaching Model for Food Literacy-based Education | N/A | Interventional | Discontinuing the study because of COVID-19 | Actual 24 |
NCT04201145 | Withdrawn | Pembrolizumab + Defactinib In Pleural Mesothelioma | Phase 1 | Interventional | Funding complications coupled with competing scientific objectives | Actual 0 |
NCT04226001 | Withdrawn | Impact of a Carrier (Infection, Colonization) of Highly Bacteria Resistance on the Patient's Quality of Life Hospital Environment | Observational | Coordinator departure | Actual 0 | |
NCT04633031 | Withdrawn | The Effect of Bracing on Sagittal Balance in Scoliosis | Observational | never approved | Actual 0 | |
NCT01474031 | Terminated | Prospective Study Deltamotion - DAA THA Study | Observational | Main investigator has left the department and therefore the study had ended | Actual 29 | |
NCT02529475 | Terminated | Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Healthy Subjects (HYDROPS) | Phase 4 | Interventional | recruitment problem-covid- | Actual 25 |
NCT02843932 | Terminated | Subjective Perception of Motor Control During Psychogenic Disorders | N/A | Interventional | recruitment difficulties | Actual 14 |
NCT02854397 | Terminated | Determination of Specific Biomarkers of Acute Attack of Angioedema Within Pediatric Population | Observational | Recruitment difficulties | Actual 31 | |
NCT03074318 | Terminated | Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery | Phase 1/Phase 2 | Interventional | Terminated due to PI leaving institution | Actual 35 |
NCT03370055 | Withdrawn | LeucoPatch® in Nonhealing Wounds With Exposed Bone or Tendon Study | N/A | Interventional | Study was closed due to lack of participants | Actual 0 |
NCT03454672 | Terminated | A Safety and Effectiveness Study of the Tixel Device, (Fractional Peri-orbital Wrinkles Treatment ) Compared With Laser | N/A | Interventional | Delay in recruitment as per last protocol amendment due to Covid-19 | Actual 68 |
NCT03976050 | Terminated | Phase I Study of HL-085 in Patients With Advanced Solid Tumors | Phase 1 | Interventional | Study objective and design change | Actual 4 |
NCT04271917 | Suspended | Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients | Phase 3 | Interventional | COVID-19 | Anticipated 120 |
NCT04347707 | Terminated | Building Regulation in Dual Generations | N/A | Interventional | The trial was ended after one year due to the suspension of in-person research as a result of the COVID-19 pandemic. We have returned to the program development stage as we explore telehealth alternative options. | Actual 28 |
NCT03271086 | Withdrawn | Relaxation Breathing Training for Children | N/A | Interventional | The study was never started. | Actual 0 |
NCT02842021 | Terminated | Efficacy and Safety of Product S2G6T-1in Patients With Symptomatic Inflammatory Interdigital Tinea Pedis | Phase 2 | Interventional | Failed to meet success criteria | Actual 283 |
NCT03173859 | Withdrawn | Efficacy of Rotations Between Abiraterone Acetate and Apalutamide in mCRPC Patients | Phase 2 | Interventional | Delayed initiation | Actual 0 |
NCT04041791 | Suspended | A Study to Compare Different Antibiotics and Different Modes of Fluid Treatment for Children With Severe Pneumonia | Phase 3 | Interventional | Temporarily suspension due to the COVID19 pandemic and will resume once it is deemed safe. | Anticipated 4392 |
NCT00820040 | Terminated | Feasibility of Permacol Use in Infected Fields | Phase 2 | Interventional | Slow enrollment due to strict eligibility criteria | Actual 10 |
NCT02957604 | Terminated | Evolocumab Pregnancy Exposure Registry | Observational [Patient Registry] | Actual 140 | ||
NCT03089463 | Suspended | Foot Assessment in People With Diabetes: A Quantitative Diagnostic Approach | Observational | The study has not managed to recruit adequate number of participants. | Anticipated 153 | |
NCT02457949 | Terminated | The Impact of Alternative Social Assistance Disbursement on Drug-related Harm | N/A | Interventional | Interim analyses produced signal of intervention efficacy for primary outcomes and weaker signal of increased exposure to violence. Therefore, DSMC recommended stopping recruitment in May 2018. Enrolled participants completed intervention by Aug 2018 | Actual 194 |
NCT02538913 | Terminated | Exercise Training for Rectal Cancer Patients | N/A | Interventional | too slow recruitment; lack of resources | Actual 25 |
NCT02596165 | Terminated | Validation of the Schiller BR-102 Plus PWA Device to Measure Central and Peripheral Hemodynamics | N/A | Interventional | Stopp because of FDA concrns regarding recruitment. | Actual 45 |
NCT03002467 | Terminated | Impact Analysis of Prognostic Stratification for Pulmonary Embolism | N/A | Interventional | Low recruitment rate | Actual 125 |
NCT03557970 | Terminated | JNJ-40346527 in Treating Participants With Relapsed or Refractory Acute Myeloid Leukemia | Phase 2 | Interventional | Not enough enrollment to determine efficacy | Actual 3 |
NCT04028635 | Terminated | Treating the Fear of Gaining Weight in Anorexia Nervosa | N/A | Interventional | The study was terminated with a total of 35 patients finally enrolled, due to the Sars-Cov-2 (COVID-19) global pandemic breakout and the confinement measures considered. | Actual 35 |
NCT00794417 | Terminated | A Study of Aflibercept Administered in Combination With Pemetrexed and Cisplatin in Participants With Advanced Carcinoma | Phase 1/Phase 2 | Interventional | Actual 60 | |
NCT04215549 | Withdrawn | The Cost of Obsessive-compulsive Disorder (OCD) in China | Observational | Because of COVID-19, we cann't carry out recruiting according to the original plan | Actual 0 | |
NCT04253067 | Withdrawn | A Single-Blind, Randomized Study to Compare fCO2 Laser Therapy Versus Sham for Treatment of SUI in Women | N/A | Interventional | PI decided not to open study, following review of data collected in another study | Actual 0 |
NCT04262375 | Withdrawn | A Phase 2 Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Multi-Cancer Populations With Correlation to Clinical, Molecular and Immunologic Parameters With DNA MethylaTION | Phase 2 | Interventional | Overall clinical activity (ORR) for oleclumab + durvalumab is minimal across tumor types and does not support further evaluation of this doublet. | Actual 0 |
NCT04262388 | Withdrawn | A Multi-Cancer, Multi-State, Platform Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Pancreatic Adenocarcinoma, Non-Small Cell Lung Cancer and Squamous Cell Carcinoma of the Head and Neck to Correlate Clinical, Molecular and Immunologic Parameters With DNA Methylation | Phase 2 | Interventional | Overall clinical activity (ORR) for oleclumab + durvalumab is minimal across tumor types and does not support further evaluation of this doublet. | Actual 0 |
NCT04290442 | Suspended | Adductor Canal Vs Adductor Canal Plus SPANK Block for Postoperative Pain in Knee Arthroplasty Surgery | Phase 4 | Interventional | initially cessation due to covid, then fellow doing the study graduated with no time to complete the study; will take up again if a current fellow takes on the project | Anticipated 70 |
NCT04345692 | Terminated | A Randomized Controlled Clinical Trial: Hydroxychloroquine for the Treatment of COVID-19 in Hospitalized Patients | Phase 3 | Interventional | RECOVERY Trial results - no efficacy | Actual 17 |
NCT04349956 | Terminated | Long-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or Placebo | Observational | Inability to achieve primary or secondary study objectives | Actual 161 | |
NCT02651272 | Terminated | Macitentan in Pulmonary Hypertension of Sickle Cell Disease | Phase 2 | Interventional | Unable to enroll IRB approved sample of participants. | Actual 4 |
NCT01543750 | Withdrawn | 4-Aminopyridine in Episodic Ataxia Type 2 | Phase 2 | Interventional | Actual 0 | |
NCT01843569 | Withdrawn | In Vitro Maturation (IVM) of Human Oocytes | N/A | Interventional | Institutional approval of study has expired. | Actual 0 |
NCT02053727 | Withdrawn | Abatacept vs Placebo in RA Patients With Hepatitis B on Entecavir Background | N/A | Interventional | The study team did not enroll any patients due to difficulty with recruitment. | Actual 0 |
NCT02331355 | Withdrawn | Hand Transplantation: Functional and Quality of Life Outcomes | Observational | unable to find appropriate candidates | Actual 0 | |
NCT02474888 | Terminated | Pharmacokinetic Study of Rituximab Induction Regimen in ANCA-associated Vasculitis | Observational | failure of recruit | Actual 28 | |
NCT02597660 | Withdrawn | A Study to Evaluate the Efficacy of Somatropin in the Treatment of Patellar Tendinopathy | Phase 2 | Interventional | PI decided not to enroll | Actual 0 |
NCT02718677 | Withdrawn | Patient-reported Outcomes in Subjects Treated With ReFacto AF Routine Prophylaxis | Observational | Company decision to not conduct study | Actual 0 | |
NCT03452540 | Suspended | Efficacy and Safety of Orally Administered DS102 in Patients With Acute Alcoholic Hepatitis | Phase 2 | Interventional | Company Decision | Anticipated 120 |
NCT03592459 | Withdrawn | Rectal Administration of Opioids Using the Macy Catheter in Reducing Pain in Patients With Advanced Cancer | N/A | Interventional | Study halted prematurely, prior to enrollment of first participant | Actual 0 |
NCT03773055 | Terminated | Phase II Clinical Trial of NPC-06 in Patients With Neuropathic Pain in Cancer | Phase 2 | Interventional | Low recruitment | Actual 7 |
NCT03773991 | Terminated | Dyspnea Assessment in Hemodialysis Patients | Observational | Recruitment issues: Restrictions associated with the COVID-19 pandemic have made much of the research procedures unfeasible due to organizational and safety issues (for both staff and patient protection). | Actual 7 | |
NCT04435808 | Terminated | Efficacy of Hydroxychloroquine Prophylaxis for Health Care Workers at High Risk for COVID-19 | Phase 1/Phase 2 | Interventional | Stopped for futility by DSMB | Actual 1 |
NCT04494178 | Terminated | G-PUR® for Reduced Dietary Fumonisin Bioavailability | N/A | Interventional | Several analytical laboratories failed to develop and validate a suitable assay of urine fumonisin (the primary endpoint) up to date. Because of missing alternatives for an analytical laboratory the objective of the study cannot be met. | Actual 7 |
NCT04540393 | Suspended | AZD1222 Vaccine for the Prevention of COVID-19 | Phase 3 | Interventional | Study has been suspended due to the occurrence of SUSAR at University of Oxford sponsored Phase2/3 study. Study will continue to be on hold until Russian MOH approval is received. | Anticipated 100 |
NCT04636372 | Withdrawn | Effect of Meibomian Gland Related Therapy on the Morphology of Meibomian Gland | N/A | Interventional | An one-month follow-up was completed after the treatment. | Actual 0 |
NCT02767570 | Terminated | Long-Term Effectiveness of Walking Training in Patients With Knee Osteoarthritis | N/A | Interventional | Study data collection was terminated due to COVID-19 pandemic and will not resume. | Actual 69 |
NCT03479463 | Terminated | Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy | Observational [Patient Registry] | Slow enrollment | Actual 8 | |
NCT04284787 | Suspended | BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia | Phase 2 | Interventional | pending amendment approval | Anticipated 76 |
NCT04628533 | Withdrawn | Exploring the Optimal Duration of a Group-based Online Behavioral Weight Loss Program | N/A | Interventional | COVID-19. Recruitment never began. | Actual 0 |
NCT02942485 | Terminated | Treatment of Giardia Lamblia Infections in Children | Phase 4 | Interventional | Extremely slow enrollment | Actual 8 |
NCT02205723 | Withdrawn | Smartphone-facilitated Asthma Control | N/A | Interventional | Study was not initiated because we could not secure funding. | Actual 0 |
NCT02234557 | Suspended | Tai Chi Training for Children With ADHD | N/A | Interventional | Due to COVID-19, we have suspended enrollment for this study. | Anticipated 40 |
NCT02431000 | Withdrawn | Male Fertility and Sperm Cryopreservation | Observational | PI is no longer at this University. | Actual 0 | |
NCT02443142 | Withdrawn | Ibuprofen Versus Acetaminophen for Treatment of Mild Traumatic Brain Injury | Phase 2 | Interventional | Lack of study participants. | Actual 0 |
NCT02458482 | Withdrawn | Trial of AccuPAP Device Versus Standard Nebulizer Therapy in Acute Asthma Exacerbation in Children | N/A | Interventional | The trainee for whom I designed the study did not begin enrollment and has left our institution. | Actual 0 |
NCT02563561 | Terminated | A Study of Intravesical Apaziquone as a Surgical Adjuvant in Patient Undergoing TURBT | Phase 3 | Interventional | Actual 62 | |
NCT02587026 | Terminated | Biorepository for Precision Genomics | Observational [Patient Registry] | Study team has decided to close enrollment, and all subjects are being rolled into a different clinical trial: Total Cancer Care | Actual 480 | |
NCT02589860 | Withdrawn | Analysis of Oral Mucositis in Patient's Undergoing Melphalan Conditioning and Autologous Stem Cell Transplant | Observational | No accrual | Actual 0 | |
NCT02844933 | Terminated | Cannabidiol Oral Solution for the Treatment of Subjects With Prader-Willi Syndrome | Phase 2 | Interventional | Insys Therapeutics filed Chapter 11 and terminated all studies. | Actual 7 |
NCT03110484 | Withdrawn | Pemetrexed in Combination With Erlotinib as a Salvage Treatment in Patients With Metastatic Biliary Tract Cancer (BTC) Who Failed Gemcitabine Containing Chemotherapy: A Phase II Single Arm Prospective Study | Phase 2 | Interventional | institution resource problem | Actual 0 |
NCT03336242 | Terminated | Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures | Phase 2 | Interventional | More patients in Cohort 1 than Cohort 2 demonstrated a clinically meaningful reduction of seizure count. Given this, enrollment of Cohort 3 was discontinued. | Actual 20 |
NCT03355300 | Terminated | Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures | Phase 2 | Interventional | Insys Therapeutics filed Chapter 11 and terminated all studies. | Actual 6 |
NCT03421496 | Terminated | A Study to Assess the Efficacy, Safety, and Tolerability of Cannabidiol Oral Solution With Vigabatrin as Initial Therapy in Participants With Infantile Spasms | Phase 3 | Interventional | The study was terminated due to slow enrollment and failure to identify adequate patients that met entry criteria. | Actual 2 |
NCT03434509 | Suspended | Ongoing Tai Chi Training for Children With ADHD | N/A | Interventional | Due to COVID-19, we have suspended enrollment. | Anticipated 50 |
NCT03458416 | Terminated | A Study to Assess the Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Patients With Prader-Willi Syndrome | Phase 2 | Interventional | Insys Therapeutics filed Chapter 11 and terminated all studies. | Actual 7 |
NCT03609450 | Terminated | Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 3) | N/A | Interventional | COVID-19 Pandemic | Actual 73 |
NCT03609749 | Terminated | Mindful Self-Regulation fMRI Study (MindfulPCfMRI) | N/A | Interventional | COVID-19 pandemic | Actual 21 |
NCT03705273 | Terminated | Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup | Phase 4 | Interventional | Dr. Arnold assisted in designing and initiating study for a pharmacology PhD candidate. The candidate left the institution and study enrollment was terminated. | Actual 40 |
NCT03967093 | Terminated | A Study of BXQ-350 in Children and Young Adults With Relapsed Solid Tumors | Phase 1 | Interventional | Bexion will not move forward with the Part 2 expansion portion of the trial in order to focus resources on the further development of BXQ-350 as an earlier treatment measure in the pediatric population. | Actual 9 |
NCT04135326 | Withdrawn | Transcranial Direct Current Stimulation in Reducing Pain in Cancer Patients With Chemotherapy Induced Peripheral Neuropathy | Early Phase 1 | Interventional | Per PI termination request, no patients enrolled | Actual 0 |
NCT04158830 | Withdrawn | Aspirin (ASA) Therapy and Preeclampsia Prevention | Phase 4 | Interventional | PI is no longer at this University. | Actual 0 |
NCT04178525 | Terminated | Clinical Trial Evaluating the Safety and Efficacy of the Use of Chitosan Gel in Patients With Chronic Wounds | N/A | Interventional | COVID-19 restrictions | Actual 46 |
NCT04194983 | Terminated | The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans | N/A | Interventional | due to COVID-19 and lack of financial means to continue | Actual 25 |
NCT04280588 | Withdrawn | Fingolimod in COVID-19 | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT03685344 | Terminated | Safety and Antitumor Activity Study of Loncastuximab Tesirine and Durvalumab in Diffuse Large B-Cell, Mantle Cell, or Follicular Lymphoma | Phase 1 | Interventional | In a limited number of patients, no additional activity was evident for the combination vs. Loncastuximab tesirine monotherapy. | Actual 13 |
NCT04199442 | Terminated | Anxiety Assessment Before Regional Anesthesia. | Observational | Sanitary crisis du to Covid-19 | Actual 200 | |
NCT04209452 | Terminated | Improving Working Memory of Children With Autism | N/A | Interventional | COVID-19 | Actual 15 |
NCT04499352 | Withdrawn | A Study to Test BI 754091 Alone or in Combination With BI 836880 in People Who Have Advanced Anal Cancer | Phase 2 | Interventional | Not due to safety reasons (sponsor decision). | Actual 0 |
NCT04550234 | Suspended | A Study in Healthy Subjects to Assess Drug Availability of 2 Different Formulations of Verinurad and Allopurinol | Phase 1 | Interventional | After internal evaluation of interim data, AZ team decided to postpone Study until Mid-2021 for further development of Phase 3 formulation. | Anticipated 48 |
NCT04625231 | Terminated | Shared Decision-Making Tool for Opioid Prescribing After Ambulatory Hand Surgery in Veterans | N/A | Interventional | Due to decreased case volume due to COVID-19 enrollment has stopped. | Actual 45 |
NCT01363882 | Terminated | Polysomnography-directed Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) | N/A | Interventional | Insufficient enrollment & high rate of failure to complete protocol | Actual 25 |
NCT02112643 | Withdrawn | Selenium in Mild Thyroid Eye Disease in North America | N/A | Interventional | Lack of funding | Actual 0 |
NCT02691455 | Terminated | The AGS Second Aqueous Shunt Implant vs. Transscleral Cyclophotocoagulation Treatment Study (ASSISTS) | N/A | Interventional | Difficulty in recruiting participants | Actual 43 |
NCT02492997 | Terminated | Clinical Evaluation of Venus Versa Octipolar Applicator for Reduction of Abdomen Circumference | N/A | Interventional | Trial was terminated early due to slow enrollment. | Actual 44 |
NCT03261479 | Terminated | Validation of Thermal Imaging to Detect Pneumonia | Observational | Research stopped after lab-based data using mouse model did not support use of technology. | Actual 22 | |
NCT03381196 | Terminated | A Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Non-Hospitalized Participants With Influenza A Infection Who Are at Risk of Developing Complications | Phase 3 | Interventional | Based on interim Analysis outcome being futile for FLZ3001; decision was taken to stop (early terminate) both FLZ3001/3002. There was no safety concern. | Actual 553 |
NCT03477526 | Terminated | Status and Develepment Mental Quality of Life COPD/IPF Inpatients Before and After Pulmonary Rehabilitation | N/A | Interventional | PhD Student stopped working on this project | Actual 1 |
NCT03810690 | Withdrawn | Open Label Study of mRNA-3704 in Patients With Isolated Methylmalonic Acidemia | Phase 1/Phase 2 | Interventional | Study was terminated before the start of dosing due to a business decision and not due to safety or efficacy reasons. | Actual 0 |
NCT03893292 | Withdrawn | Preop Cooled Radiofrequency Ablation for Total Knee Replacement | Observational | Lack of participants | Actual 0 | |
NCT04030624 | Withdrawn | Remote Electronic Patient Monitoring in Gastrointestinal Cancer | N/A | Interventional | Funding discontinued due to changes in corporate structures | Actual 0 |
NCT04061317 | Terminated | SPOT-FRAILTY Assessment of Frailty in Patients Over the Age of 70 Undergoing a Cardiac Intervention | Observational | COVID Restrictions in a vulnerable population. | Actual 82 | |
NCT04225299 | Withdrawn | Evaluation of Efficacy of TOOKAD® (VTP) Versus Active Surveillance for Intermediate Risk Localized Prostate Cancer | Phase 3 | Interventional | FDA didn't approve the design of the protocol so we didn't start the study | Actual 0 |
NCT04356456 | Withdrawn | A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects | N/A | Interventional | Covid-19 | Actual 0 |
NCT01743976 | Terminated | Donepezil Compared to Placebo in Patients With Chronic Neuropathic Pain | Phase 4 | Interventional | Failure to recruit subjects | Actual 5 |
NCT01632202 | Terminated | Seprafilm Slurry in the Prevention of Uterine Scarring in Patients Undergoing Hysteroscopic Myomectomy | Phase 4 | Interventional | No subjects were recruited at the Weill Cornell site. | Actual 11 |
NCT03376256 | Terminated | Compuflo Instrument for Thoracic ES Identification | N/A | Interventional | Difficulty in participant recruitment | Actual 2 |
NCT02906124 | Terminated | Study to Evaluate the Safety of Repatha® in Pregnancy | Observational | Actual 4 | ||
NCT03041688 | Suspended | KRT-232 (AMG-232) and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia | Phase 1 | Interventional | Other - to update dosing schedule | Anticipated 58 |
NCT03578731 | Terminated | Efficacy of the "Consilium" Smartphone App for Detecting Symptoms and Treatment Side Effects in Cancer Patients | Observational | Mainly due to insufficient recruitment | Actual 224 | |
NCT03731728 | Terminated | Group CBT and Exercise in Management of Depression | N/A | Interventional | COVID-19 | Actual 70 |
NCT03913676 | Terminated | Disseminating a Waitlist Treatment for Anxiety With Velibra | N/A | Interventional | The study was not feasible. | Actual 11 |
NCT04020211 | Terminated | HF10 Treatment of Chronic Knee Pain | Observational | Limited Enrollment | Actual 3 | |
NCT04028960 | Terminated | IN Insulin in Type 1 Diabetes (T1D) Hypoglycemia Unawareness: Safety Only Phase | Phase 2 | Interventional | Funding was rescinded | Actual 5 |
NCT04366232 | Terminated | Efficacy of Intravenous Anakinra and Ruxolitinib During COVID-19 Inflammation (JAKINCOV) | Phase 2 | Interventional | investigator decision | Actual 2 |
NCT04393727 | Terminated | Transfusion of Convalescent Plasma for the Early Treatment of Patients With COVID-19 | Phase 2 | Interventional | Study was stopped because the Promoter was changed and a new study on convalescent plasma promoted by AIFA was started in Italy. | Actual 1 |
NCT04493099 | Withdrawn | Alvocidib in Combination With Decitabine and Venetoclax in Patients With Relapsed or Refractory AML or as Frontline Therapy in Unfit Patients With AML | Phase 1/Phase 2 | Interventional | The original sponsor was acquired by a new company and has elected to end funding for all Investigator Sponsored Trials (ISTs) | Actual 0 |
NCT04628819 | Terminated | Effect and Tolerability of Lactobacillus Rhamnosus GG LA801 for the Preventive Nutritional Care of Nosocomial Diarrhea in Children | N/A | Interventional | Not enough patients included | Actual 61 |
NCT04629417 | Suspended | Measuring Adherence to Home Shoulder Physiotherapy With Artificial Intelligence | N/A | Interventional | Due to COVID-19 all research activities including recruitment have been paused. | Anticipated 120 |
NCT01848431 | Withdrawn | Randomized Study on the Effects of Moderate Anaemia in Free Microvascular Tissue Transfer | Observational | staff change and lack of ressources | Actual 0 | |
NCT04188574 | Suspended | A Trial Involving Treatment of BB2603 in Subjects With Distal Subungual Onychomycosis of the Toenail | Phase 2 | Interventional | Study pause due to COVID-19 pandemic impacts. | Anticipated 220 |
NCT01925378 | Withdrawn | A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia | Phase 2 | Interventional | The study is going to open in a new site | Actual 0 |
NCT02196311 | Withdrawn | Treatment Of Supracondylar Fractures Closed Reduction And Circular Ring External Fixation Versus Open Reduction and Internal Fixation | Observational | no patient recruited | Actual 0 | |
NCT02761928 | Terminated | Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients | Observational | Insufficient enrollment, lack of funding to continue | Actual 31 | |
NCT03655444 | Terminated | Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy | Phase 1/Phase 2 | Interventional | Provider of drug decided to discontinue study. | Actual 6 |
NCT02782403 | Terminated | Axitinib and Bosutinib in Treating Patients With Chronic, Accelerated, or Blastic Phase Chronic Myeloid Leukemia | Phase 1/Phase 2 | Interventional | Terminated per PI's request at the time of CR | Actual 6 |
NCT02842710 | Withdrawn | Staphylococcus Aureus Resistant to Methicillin (MRSA) Screening in Trauma | N/A | Interventional | the study did not start due to a lack of staff | Actual 0 |
NCT02850731 | Withdrawn | Motorized Platform and Autonomy Among the Frail and Pre-frail Older Adult (PLATAUTONOMIE) | N/A | Interventional | Organisation problem | Actual 0 |
NCT02897830 | Terminated | Ixazomib, Lenalidomide, Dexamethasone Induction and Extended Consolidation Plus Lenalidomide Maintenance in Multiple Myeloma | Phase 2 | Interventional | negatives results | Actual 46 |
NCT03100006 | Terminated | Phase Ib/IIa Trial to Evaluate Oregovomab and Nivolumab in Epithelial Cancer of Ovarian, Tubal or Peritoneal Origin | Phase 1/Phase 2 | Interventional | The study had poor efficacy. | Actual 13 |
NCT02077530 | Withdrawn | Metabolic Syndrome Cohort in Korea | Observational [Patient Registry] | Actual 0 | ||
NCT02642146 | Terminated | Treatment of Digital Ulcers in Korean Patients With Systemic Sclerosis: a Prospective Cohort Study | Observational [Patient Registry] | We decided to terminate recruit earlier because patient recruiting was not active as expected at the beginning of the study. | Actual 71 | |
NCT04183738 | Withdrawn | Inflammation and Co-Infections in D²EFT | Phase 4 | Interventional | In the context of COVID-19 pandemic. | Actual 0 |
NCT02444585 | Withdrawn | Longjohn Amgen Study - Effect of Denosumab... | Phase 1 | Interventional | No participants enrolled in the trial | Actual 0 |
NCT04214249 | Suspended | BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia | Phase 2 | Interventional | Other - pending protocol updates | Anticipated 124 |
NCT00948025 | Terminated | A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options | N/A | Interventional | transitioning from 361 HCT/P Tissue to a Biologic (BLA) | Actual 23 |
NCT02230527 | Terminated | Establishing the Microcirculatory Effects of Ticagrelor on Tissue Perfusion in Critical Limb Ischemia | Phase 2/Phase 3 | Interventional | Lack of enrollment | Actual 27 |
NCT03202108 | Withdrawn | Evaluation of Krio in Children and Adults With Epilepsy | N/A | Interventional | Product manufacturing issues. | Actual 0 |
NCT00330434 | Withdrawn | Effect of Ethanol and Genetic Polymorphisms on Bupropion Metabolism | N/A | Interventional | Study was a F32 Fellowship. Trial was proposed however Principle Investigator does not believe trial took place. | Actual 0 |
NCT01197482 | Terminated | Inhaled Steroids and Control of Severe Asthma | Observational | 6 out of 20 patients were included. The trend towards the treatment of severe asthma has meanwhile developed in a different direction, so that there is no longer any intention to pursue the study objective mentioned here. | Actual 6 | |
NCT03143894 | Terminated | Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation | N/A | Interventional | Poor accrual (inability to enroll participants) | Actual 7 |
NCT03963869 | Suspended | Effectiveness of Malaria Camps as Part of the Odisha State Malaria Elimination Drive | N/A | Interventional | The study has been suspended because of COVID-19. We will resume as soon as COVID-19 restrictions are lifted. | Anticipated 2700 |
NCT04274907 | Suspended | A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression | Phase 1 | Interventional | Company Decision | Actual 2 |
NCT01998035 | Terminated | Romidepsin Plus Oral 5-Azacitidine in Relapsed/Refractory Lymphoid Malignancies | Phase 1/Phase 2 | Interventional | PI left institution | Actual 52 |
NCT02004353 | Terminated | Observation of Benefits for Patients Implanted With a Hearing Implant of the Company Cochlear | Observational [Patient Registry] | Original study purpose accomplished | Actual 1518 | |
NCT01745224 | Terminated | Revlite Laser System Compared to the Candela Alex TriVantage System Refractory Mixed Type Melasma | N/A | Interventional | The study stopped because patient enrollment requirements were not met. | Actual 10 |
NCT02790034 | Terminated | Evaluation of the Efficacy, Safety, and Tolerability of Sarizotan in Rett Syndrome With Respiratory Symptoms | Phase 2/Phase 3 | Interventional | The study did not demonstrate evidence of efficacy on the primary or secondary efficacy variables | Actual 129 |
NCT03105219 | Withdrawn | IvaBradinE to Treat MicroalbumiNuria in Patients With Type 2 Diabetes and Coronary Heart Disease | Phase 3 | Interventional | Shortfall in funding | Actual 0 |
NCT03275792 | Withdrawn | Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion | Phase 1 | Interventional | Funding not obtained. | Actual 0 |
NCT03702062 | Withdrawn | Dynamic Heart Failure Prediction With Real-time Functional Status Data in the Ambulatory Setting | N/A | Interventional | Study never started | Actual 0 |
NCT03857659 | Suspended | Serial Third Trimester Abdominal Circumference and Amniotic Fluid Measurements Versus Routine Care | N/A | Interventional | COVID related termination | Actual 113 |
NCT03922711 | Terminated | A Study to Assess the Safety and Effectiveness of Pridopidine Compared to Placebo in the Treatment of Levodopa-Induced Dyskinesia in Patients With Parkinson's Disease | Phase 2 | Interventional | COVID-19 | Actual 23 |
NCT03949998 | Withdrawn | The Immediate Effects of Dry Needling on Post-concussion Syndrome | N/A | Interventional | no participants | Actual 0 |
NCT03962231 | Suspended | Exercise Program in Patients With Shoulder Pain and Rotator Cuff Tear | N/A | Interventional | Coronavirus | Anticipated 78 |
NCT04042077 | Terminated | Delafloxacin IV and OS Administration Compared to Best Available Therapy in Patients With Surgical Site Infections | Phase 3 | Interventional | COVID-19 seriously affected the study execution as required by the protocol | Actual 269 |
NCT04149769 | Withdrawn | Mobility and Therapeutic Benefits Resulting From Exoskeleton Use in a Home and Community Setting (SC140121 Study 3) | N/A | Interventional | COVID | Actual 0 |
NCT02867618 | Terminated | Carfilzomib and TGR-1202 in Treatment of R/R Lymphoma | Phase 1/Phase 2 | Interventional | PI left institution | Actual 11 |
NCT04352868 | Withdrawn | Customizing Myopia Control With Multifocal Toric Contact Lens | N/A | Interventional | COVID-19 | Actual 0 |
NCT04621955 | Withdrawn | Observational Study of Home Administration of Carfilzomib | Observational | Not possible to conduct study | Actual 0 | |
NCT03163277 | Terminated | Using Less Neurotoxic Drugs in Patients With HAND (MARAND-X) | Phase 4 | Interventional | Sloww accrual and COVID-19 related problems (impossible to perform LPs) | Actual 38 |
NCT03424031 | Terminated | A Very Early Standing Study in Elderly Stroke | N/A | Interventional | Many study exits (many deaths, aggravations) that we had anticipated (but not enough). The patients did not stay long enough in the department to complete the protocol (many study exits that we had not anticipated). | Actual 45 |
NCT04339816 | Terminated | Azithromycin Added to Hydrochloroquine in Patients Admitted to Intensive Care With COVID-19: Randomised Controlled Trial | Phase 3 | Interventional | Steering Committee decision in accordance with stopping rule 1: Emergence of new data | Actual 3 |
NCT04356040 | Suspended | TactiFlex PAF IDE Trial | N/A | Interventional | Enrollment suspended due to temporary device unavailability. | Anticipated 355 |
NCT00537446 | Terminated | Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis | N/A | Interventional | Insufficient enrollment | Actual 8 |
NCT04197219 | Withdrawn | Pembrolizumab With Axitinib in Recurrent Endometrial Cancer | Phase 2 | Interventional | PI is leaving institution | Actual 0 |
NCT01857557 | Terminated | Evaluation of an Aerobic Exercise Program in Migraine Management | N/A | Interventional | Challenges with participant recruitment as a result of COVID-19 pandemic | Actual 39 |
NCT02775149 | Suspended | Dental Erosion in Patients With Gastro-oesophageal Reflux | Observational | No participants | Anticipated 30 | |
NCT03033316 | Terminated | A Evaluation of the Safety of Oncocort IV Pegylated Liposomal Dexamethasone Phosphate in Patients With Progressive Multiple Myeloma | Phase 1/Phase 2 | Interventional | Patient enrolment issues | Actual 7 |
NCT03537131 | Suspended | Dapagliflozin During Exercise for the PrevenTion of Hypoglycaemia | Phase 2 | Interventional | Temporary halt due to COVID-19 pandemic | Anticipated 34 |
NCT03587896 | Terminated | Implementation of Self Help Plus in Adult Syrian Refugees in Turkey (RE-DEFINE) | N/A | Interventional | 12-month assessment process has been stopped prematurely due to logistic reasons. | Actual 642 |
NCT03629821 | Suspended | Effect of Classic Ballet Practice on School Children's Postural Balance | N/A | Interventional | The study has been suspended because COVID pandemic. | Anticipated 50 |
NCT03637257 | Withdrawn | Carbon Dioxide (CO2) Measurement With a CO2/O2 Guedel Airway | N/A | Interventional | due to other priorities | Actual 0 |
NCT03684369 | Withdrawn | Improving Mobility and Reducing Fatigue in People With Multiple Sclerosis by Electrical Stimulation Therapy | N/A | Interventional | The project was not funded. | Actual 0 |
NCT03743571 | Suspended | Augmenting Exposure Therapy for Social Anxiety With Transcranial Direct Current Stimulation | N/A | Interventional | recruitment suspended due to COVID-related social distancing requirements | Anticipated 128 |
NCT03827902 | Withdrawn | Diabetic Foot Ulcer and Wound Infection | Observational | Unable to recruit participants | Actual 0 | |
NCT03884959 | Withdrawn | A Safety and Efficacy Study of Infusions of HepaStem in Urea Cycle Disorders Pediatric Patients | Phase 2 | Interventional | Sponsor decided to stop enrollment | Actual 0 |
NCT03892525 | Suspended | Study of Intratumoral Selicrelumab With Atezolizumab in Patients With Refractory or Relapsed B Cell Lymphoma | Phase 1 | Interventional | End of drug development | Actual 4 |
NCT03917433 | Suspended | Augmenting Virtual Reality Exposure Therapy for Acrophobia | N/A | Interventional | temporarily suspended recruitment due to COVID-related social distancing requirements | Anticipated 128 |
NCT03962829 | Terminated | Effect of mCPP on Cognitive Control, Appetite, and Neural Responses | N/A | Interventional | due to the Covid 19 pandemic | Actual 32 |
NCT04181957 | Terminated | Effects of LDX on Cognitive Processes and Appetite | N/A | Interventional | COVID-19 | Actual 22 |
NCT04340102 | Withdrawn | Development of a Scalable Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness | N/A | Interventional | Study was not funded. | Actual 0 |
NCT04364815 | Withdrawn | The University of the Philippines Hydroxychloroquine PEP Against COVID-19 Trial | Phase 3 | Interventional | Investigators opted to change the design of the study. | Actual 0 |
NCT04399824 | Withdrawn | Focal Radiation Therapy for the Treatment of Low or Intermediate-Risk Prostate Cancer | N/A | Interventional | Study did not open | Actual 0 |
NCT03699033 | Withdrawn | Hypofractionated Radiotherapy With Carboplatin and Paclitaxel in Non-Small Cell Lung Cancer | Phase 2 | Interventional | No patients available | Actual 0 |
NCT03844152 | Terminated | RIGHTWHEY - Responders In Gut HealTh Markers Using Fermented WHEY | N/A | Interventional | COVID-19 | Actual 43 |
NCT03869008 | Terminated | Potential Benefit for Non Invasive Vagus Nerve Stimulation Using GammaCore in the Treatment of Raynaud's Phenomena. | N/A | Interventional | Funding no longer available | Actual 7 |
NCT03941119 | Terminated | Evaluating the Impact of VR-therapy on BPSD and QoL of Individuals With Dementia Admitted to Hospital | N/A | Interventional | All recruitment activities for this study (with acutely ill inpatients with dementia) stopped due to the COVID pandemic. | Actual 77 |
NCT03974984 | Withdrawn | Anesthesia and Immunological and Oxidative Stress in Relation to Abdominal Cancer Surgery | Observational | Not feasable due to logistics | Actual 0 | |
NCT04047966 | Terminated | Study of the Fetal and Maternal Microbiota in Preganant Women With Fetal Defect Growth | Observational | Due to the current pandemic situation, recruitment has been disrupted by the inability to recruit more patients | Actual 42 | |
NCT04094766 | Withdrawn | Safety and Efficacy of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy in R/R Acute B Lymphoblastic Leukemia | Phase 1 | Interventional | Production plan adjustment | Actual 0 |
NCT04154059 | Suspended | Strengthening Program for Foot-ankle Muscles in People With Knee Osteoarthritis | N/A | Interventional | The recruitment of potential participants is suspended due to the covid-19 pandemic. | Anticipated 76 |
NCT04160182 | Withdrawn | Feasibility and Effectiveness of an Internet-based Intervention to Manage Fatigue in Breast Cancer Survivors | N/A | Interventional | Due to COVID this trial never got up and running. | Actual 0 |
NCT04230330 | Withdrawn | Nivolumab in Combination With GDP/ L-asparaginase in NK/ T-cell Lymphoma | Phase 1 | Interventional | PI has left the institution. | Actual 0 |
NCT04232319 | Withdrawn | Feasibility and Effectiveness of a Sleep Hygiene Education Program for Sleep Issues in Breast Cancer Survivors | N/A | Interventional | Due to COVID this study was never started. | Actual 0 |
NCT04232501 | Suspended | Radial, Sequential Compression Device Deep Venous Thrombosis Detection Study | N/A | Interventional | Due to COVID-19, Radial slowed their operations. Hence the investigational device is not available. | Anticipated 200 |
NCT04295681 | Suspended | Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Cognitive Disorders | Phase 3 | Interventional | Due to pandemic COVID-19 | Anticipated 246 |
NCT01930838 | Withdrawn | Complications After Bariatric Surgery - a Clinical Trial | Observational [Patient Registry] | Actual 0 | ||
NCT02464280 | Terminated | Tomosynthesis of Pathologies of the Chest and Skeletal Structures in Comparison to CT | Observational | Actual 60 | ||
NCT02953366 | Withdrawn | Efficacy and Safety of the Mometasone Nasal Gel in the Treatment of Persistent Allergic Rhinitis | Phase 3 | Interventional | Sponsor decision | Actual 0 |
NCT02953379 | Withdrawn | Efficacy and Safety of the Mometasone Nasal Gel in the Treatment of Persistent Allergic Rhinitis | Phase 3 | Interventional | Sponsor decision | Actual 0 |
NCT01781611 | Terminated | Dipyridamole Assessment for Flare Reduction in Systemic Lupus Erythematosus (SLE) | N/A | Interventional | Slow recruitment | Actual 18 |
NCT04620421 | Suspended | Effect of Rhythm-based Multitask Training on Falls Among Older Adults | N/A | Interventional | COVID-19 | Anticipated 126 |
NCT03839472 | Suspended | Continuous Bladder Irrigation Following Transurethral Resection of Bladder Tumors | N/A | Interventional | Revision to improve cell recovery | Anticipated 20 |
NCT00120731 | Withdrawn | Effects of Potassium Citrate in Urine of Children With Elevated Calcium in Urine and Kidney Stones | N/A | Interventional | Determined not feasible | Actual 0 |
NCT00986440 | Terminated | Study of CS-7017 in Colorectal Cancer Patients Who Have Achieved Disease Control Following First-Line Chemotherapy | Phase 2 | Interventional | Due to changes to the standard of care within the proposed market for CS-7017. | Actual 84 |
NCT01068171 | Withdrawn | Developing a Diabetic Foot Ulcer Protocol | N/A | Interventional | no patients who met enrollment criteria | Actual 0 |
NCT01960764 | Withdrawn | Examination of Whether Host Preconditioning Modifies Short-term Transplant Survival | Phase 1 | Interventional | This sub-study was not done because main study results reached significance. | Actual 0 |
NCT02144142 | Withdrawn | Evaluation of the Kinetic Properties of an Autologous Microbiome Transplant in Adult Atopic Dermatitis Patients | Phase 2 | Interventional | This sub-study was not done because main study results reached significance. | Actual 0 |
NCT02538887 | Withdrawn | Use of a Supplemental Radiofrequency Detection System Subsequent to Manual Counting of Vaginal Textiles Following Vaginal Birth | Observational | Sponsor dissolved before study started | Actual 0 | |
NCT02555384 | Withdrawn | AMblyopia Treatment Through PErceptual Training in Children (AMPEL) | N/A | Interventional | Inclusion and Exclusion criteria too stringent, no patient coluld be recruited | Actual 0 |
NCT02573519 | Terminated | Gastrointestinal Motility Among Diabetes Patients | N/A | Interventional | Renewal of PET/CT scanners and slow recruitment | Actual 40 |
NCT02942758 | Terminated | Low-dose AZA, Pioglitazone, ATRA Versus Standard-dose AZA in Patients >=60 Years With Refractory AML | Phase 2 | Interventional | Due to financial reasons. | Actual 10 |
NCT02973295 | Withdrawn | Silymarin in NAFLD | Phase 4 | Interventional | Sponsor withdrawn their agreement | Actual 0 |
NCT03043898 | Terminated | Mapping Sound Propagation Through the Human Lung for Better Diagnosis | Observational | COVID-19 | Actual 62 | |
NCT03065634 | Terminated | Return to Work and Living Healthy After Head and Neck Cancer | N/A | Interventional | insufficient recruitment rate | Actual 39 |
NCT03229850 | Suspended | Dynamics of Insulin Absorption in Subclinical Lipohypertrophy Using the Euglycemic Clamp Technique | N/A | Interventional | Study was suspended due to current COVID 19 research curtailment | Anticipated 10 |
NCT03246620 | Terminated | Oral Olanzapine Versus Haloperidol or Diazepam | Phase 4 | Interventional | The study was terminated prematurely due to difficulties in patient recruitment and associated potential for selection bias. | Actual 12 |
NCT02151903 | Terminated | Open-Label Extension Study of De-immunized DI-Leu16-IL2 Immunocytokine Administered in Participants With B-cell NHL | Phase 1/Phase 2 | Interventional | Clinical benefit was noted before the scheduled completion of the trial and the extension study was terminated early. | Actual 5 |
NCT02446509 | Terminated | A Psychoeducation Intervention for Caregivers of Patients With Bipolar Disorder | N/A | Interventional | Actual 12 | |
NCT03168490 | Suspended | In Vivo Effects of the Gluten Friendly Bread in Coeliac Disease | N/A | Interventional | Anticipated 60 | |
NCT00601848 | Terminated | Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura | Phase 2 | Interventional | Poor accrual and change in standards of care | Actual 9 |
NCT01874288 | Terminated | A Study of De-immunized DI-Leu16-IL2 Administered Subcutaneously in Participants With B-cell NHL | Phase 1/Phase 2 | Interventional | Clinical benefit was noted in the earlier portion of the trial; hence, participants were not enrolled in 2 expansion cohorts and the study was terminated early. | Actual 24 |
NCT02241343 | Terminated | Venous Occlusion and Limb Swelling | N/A | Interventional | Safety concerns | Actual 1 |
NCT04325165 | Withdrawn | DBS of PPN to Improve Walking in Chronic SCI Patients | N/A | Interventional | Recruitment issues | Actual 0 |
NCT00793013 | Withdrawn | Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation | Phase 2 | Interventional | IRB approval lapsed. | Actual 0 |
NCT01822275 | Terminated | Phase II Trial of Low-Dose Whole Brain Radiotherapy With Concurrent Temozolomide and Adjuvant Temozolomide in Patients With Newly-Diagnosed Glioblastoma Multiforme | Phase 2 | Interventional | Poor accrual | Actual 23 |
NCT01922895 | Suspended | Novel Therapies in Moderately Severe Acute Alcoholic Hepatitis | N/A | Interventional | Lack of funding | Actual 53 |
NCT01925573 | Terminated | Optune(NOVOTTF-100A)+ Bevacizumab+ Hypofractionated Stereotactic Irradiation Bevacizumab-Naive Recurrent Glioblastoma (GCC 1344) | N/A | Interventional | Poor accrual | Actual 7 |
NCT02020707 | Suspended | Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery or Gynecological Cancers | Phase 1 | Interventional | pending resolution of budget issues. | Anticipated 36 |
NCT02435446 | Terminated | Cone Beam and CT Scan for the Diagnosis of Otosclerosis (TACOS) | N/A | Interventional | PROBLEM of inclusion | Actual 31 |
NCT02490332 | Terminated | The Effects of Ventilation Tubes - The SIUTIT Trial | N/A | Interventional | Failed to include the required number of participants | Actual 31 |
NCT02717390 | Terminated | Bright by Three (BB3) Effectiveness Study | N/A | Interventional | Lack of funding to recruit target sample size | Actual 100 |
NCT02754466 | Suspended | Oral Health and Its Relation to Development and Well-being of Schoolchildren Before and After Restorative Treatments | N/A | Interventional | Children could not be examined due to COVID-19 pandemic and schools closure. | Actual 270 |
NCT02765425 | Withdrawn | Training the Brain With a Robotic Device for Balance Recovery | N/A | Interventional | Loss of department staff and COVID | Actual 0 |
NCT02765737 | Terminated | Dehydrated Human Amnion Chorion Membrane (dHACM) vs. Control in the Treatment of Partial Thickness Burns. | N/A | Interventional | Slow enrollment, issues with inclusion/exclusion and choice of control | Actual 23 |
NCT02992782 | Suspended | Decongestive Exercise and Compression for Breast Cancer Related Lymphedema Management | N/A | Interventional | Covid-19 | Anticipated 60 |
NCT03160157 | Withdrawn | Comparing the Outcomes of Laparoscopic Cholecystectomy vs. Robotic Cholecystectomy | Observational | No enrollment | Actual 0 | |
NCT02086331 | Terminated | Evaluation of Musculoskeletal Microcirculation With Ultrasound | N/A | Interventional | Actual 5 | |
NCT03503435 | Withdrawn | The Effect of Art Therapy on Total Laryngectomy Patients | N/A | Interventional | Due to COVID-19 we are not able to recruit in the foreseeable future | Actual 0 |
NCT03512483 | Withdrawn | VCH -- vAFC Phase 3 | N/A | Interventional | COVID-19 | Actual 0 |
NCT03546504 | Terminated | Program to Improve Dental Care: Children With ASD | N/A | Interventional | ran out of money | Actual 3 |
NCT03642990 | Suspended | NR in Chemo-induced Peripheral Neuropathy | Phase 2 | Interventional | Evaluating safety data | Anticipated 39 |
NCT03684278 | Suspended | Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind Multi-centre Trial (RAPID-I) | Phase 2 | Interventional | COVID-19 Pandemic | Anticipated 290 |
NCT03742375 | Terminated | Quantitative HPV Genotyping in Screening of Anal Intraepithelial Neoplasia in HIV-positive Patients | N/A | Interventional | COVID-19 pandemic | Actual 24 |
NCT03847324 | Suspended | Physiotherapy and Therapeutic Education on Patients With Pain Catastrophism Scheduled for a Total Knee Arthroplasty | N/A | Interventional | COVID-19 | Anticipated 60 |
NCT03889158 | Terminated | Effect of Age and Fitness on Vascular Function and Oxidative Stress During Acute Inflammation | Phase 4 | Interventional | COVID-19 | Actual 34 |
NCT03924622 | Terminated | Pressure Injury Prevention in AE and PFC | N/A | Interventional | Unable to continue to conduct study procedures due to pandemic | Actual 54 |
NCT04010136 | Suspended | Identification of Elderly Patients in Need of Palliative Care by Family Physicians | N/A | Interventional | We were not able to recruit participants to enrol the study. As it was not able, the investigation team decided not to proced. | Anticipated 180 |
NCT04011098 | Terminated | Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour | Phase 1 | Interventional | Unable to meet recruitment numbers, lack of participation | Actual 5 |
NCT04072484 | Terminated | Effectiveness of Chest Compressions Under Mild Hypoxia | N/A | Interventional | Research at the University of Chicago was halted in March 2020. | Actual 19 |
NCT04081506 | Withdrawn | Targeting the Optimal Mean Arterial Pressure in Hypoxic Ischemic Brain Injury After Cardiac Arrest | N/A | Interventional | COVID-19 pandemic | Actual 0 |
NCT04087265 | Withdrawn | Accuracy of Trans-abdominal Ultrasound in Evaluating Bowel Preparation Adequacy Before Colonoscopy | N/A | Interventional | The PI requested to terminate due to his schedule | Actual 0 |
NCT04128462 | Withdrawn | MNK-6105 for Patients With Cirrhosis and High Ammonia Levels Affecting Brain Function | Phase 3 | Interventional | Study postponed before recruiting any participants - may start in 2nd or 3rd quarter 2021 | Actual 0 |
NCT04138433 | Suspended | Mechanisms Underlying Spoken Language Production | N/A | Interventional | Due to COVID-19 - recruitment suspended since March 2020 in line with guidance from the UCLH/UCL Joint Research Office | Anticipated 60 |
NCT04141904 | Suspended | Tofacitinib in Depression (TIDE) | Phase 1/Phase 2 | Interventional | Covid-19 pandemic | Anticipated 50 |
NCT04279249 | Suspended | Home Air Filtration for Traffic-Related Air Pollution | N/A | Interventional | Due to COVID-19 | Anticipated 288 |
NCT04292392 | Withdrawn | Pain Levels and Opioid Usage in Three Nerve Block Cohorts in Primary TKA | N/A | Interventional | Final protocol and ICF has not been approved by local IRB. No subjects have been enrolled. Study will not be pursued due to current COVID-19 pandemic. | Actual 0 |
NCT04556032 | Terminated | Effects of Ergothioneine on Cognition, Mood, and Sleep in Healthy Adult Men and Women | N/A | Interventional | Sponsor terminated study due to unforeseen recruitment circumstances amidst the COVID19 pandemic. | Actual 4 |
NCT04573010 | Withdrawn | Reducing Intracranial atheroSclErosis With Repatha | Phase 4 | Interventional | Duplicate entry | Actual 0 |
NCT02483000 | Terminated | Anti-CD20 Radioimmunotherapy Before Chemotherapy and Stem Cell Transplant in Treating Patients With High-Risk B-Cell Malignancies | Phase 1 | Interventional | Closed early due to lack of funding | Actual 3 |
NCT02455024 | Terminated | An Observational Registry to Evaluate the Incidence of and Risk Factors for Vascular Occlusive Events Associated With ICLUSIG® | Observational | Business Decision; Insufficient Enrollment | Actual 3 | |
NCT03184584 | Terminated | Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome | Phase 2/Phase 3 | Interventional | Terminated early due to redeployment of study site staff during Covid-19 pandemic | Actual 10 |
NCT03523507 | Terminated | fMRI-neuronavigated rTMS Treatment for Symptoms of Depression Associated With Concussive TBI in the Military Population | N/A | Interventional | Study terminated due to COVID-19 restrictions | Actual 10 |
NCT03879200 | Terminated | Group Antenatal Care for Somali Born Women | N/A | Interventional | Limited time frame and financial resources. The anticipated increase of eligable migrant women did not occur during the period because of changes in migration policies. | Actual 136 |
NCT04164758 | Terminated | Study to Evaluate Safety and Daytime Sedation in Subjects With Parkinson's Disease With Neuropsychiatric Symptoms Treated With Pimavanserin or Low-Dose Quetiapine | Phase 2 | Interventional | Study enrollment impacted by COVID-19 pandemic and Sponsor terminated for business reasons | Actual 11 |
NCT04231409 | Terminated | Fast-Acting Subperception Study (FAST) | N/A | Interventional | Study follow-up activities affected by COVID-19 | Actual 41 |
NCT04269265 | Suspended | The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Vaccination | Phase 1/Phase 2 | Interventional | Recruitment is suspended and expected to resume Spring 2021. | Anticipated 46 |
NCT04560972 | Withdrawn | LB-100, Carboplatin, Etoposide, and Atezolizumab for the Treatment of Untreated Extensive-Stage Small Cell Lung Cancer | Phase 1 | Interventional | Administrative isse. Study team notified me to withdraw the study. | Actual 0 |
NCT04612985 | Withdrawn | Evaluation of the XACT Robotic System for Image-guided Percutaneous Lung Procedures | N/A | Interventional | The IDE wasn't approved | Actual 0 |
NCT02936037 | Terminated | Effect of MD1003 in Progressive Multiple Sclerosis (SPI2) | Phase 3 | Interventional | Sponsor decision for business purposes | Actual 642 |
NCT03334669 | Suspended | Family-centered Obesity Prevention: Communities for Healthy Living (CHL) | N/A | Interventional | The primary trial was halted due to covid-19 in the last 6 months of the trial; as a result, the intervention was not fully implemented and the final outcomes were not measured. Outcomes will be assessed with the data available (BL, Y1, Y2). | Actual 4280 |
NCT03762356 | Withdrawn | Questionnaire About Individual's Insight/Awareness of Risk of Violence | Observational | Study did not receive final approval however it was decided to not pursue. | Actual 0 | |
NCT04001998 | Withdrawn | Healthy Volunteer Study Comparing Tablet and Capsule Formulations | Phase 1 | Interventional | On hold to determine chosen formulations | Actual 0 |
NCT04610606 | Terminated | Pilot Prehabilitation Intervention in Lung Cancer | N/A | Interventional | Covid-19 pandemic | Actual 34 |
NCT01020864 | Withdrawn | Cetuximab in Combination With Chemotherapy for Patients With Head and Neck Cancer | Phase 2 | Interventional | Actual 0 | |
NCT01668277 | Terminated | Effects of Saline on Circulation in Children | Phase 2 | Interventional | Actual 15 | |
NCT01865630 | Withdrawn | Safety and Efficacy Study of Etanercept for Aneurysmal Subarachnoid Hemorrhage | Phase 1 | Interventional | PI moved to another institution | Actual 0 |
NCT03467633 | Terminated | Atrial Fibrillation Trial to Evade Recurrence: effectS of Hiit Before electrO-Cardioversion for 3-weeKs | N/A | Interventional | Not enough participants recruited. | Actual 12 |
NCT03948334 | Terminated | A Study to Assess the Safety and Efficacy of ZPL389 With TCS/TCI in Atopic Dermatitis Patients | Phase 2 | Interventional | Coe terminated due to lack of efficacy | Actual 123 |
NCT04001153 | Withdrawn | Occlusal Compensation After the Hall Technique | Observational | There will be no opportunity to recruit patients during the pandemic of COVID-19 and possibly even post-pandemic | Actual 0 | |
NCT04108143 | Suspended | Use of MonitorMe in COPD | N/A | Interventional | COVID-19 (study will re-open for recruitment when possible) | Anticipated 30 |
NCT04171089 | Withdrawn | Suicide Prevention in Prepubertal Children | N/A | Interventional | Due to COVID-19 Pandemic | Actual 0 |
NCT04340544 | Terminated | Hydroxychloroquine for the Treatment of Mild COVID-19 Disease | Phase 2 | Interventional | It appeared to be impossible for the study centres to recruit the targeted number of patients, due to reduced incidence and reduced acceptance to IMP | Actual 17 |
NCT04374552 | Withdrawn | Asymptomatic COVID-19 Trial | Phase 2 | Interventional | The investigators have decided not to go forward with this protocol | Actual 0 |
NCT04452643 | Withdrawn | Efficacy of BACMUNE (MV130) in the Prevention of Disease Due to COVID-19 Infection in Healthcare Personnel | Phase 3 | Interventional | Not authorized by Cofepris (Mexico Competent Regulatory Authority) | Actual 0 |
NCT04469491 | Suspended | Treatment of COVID-19 by Nebulization of Inteferon Beta 1b Efficiency and Safety Study | Phase 2 | Interventional | In anticipation for Data and Safety Monitoring Board | Anticipated 60 |
NCT04610996 | Withdrawn | The Valid of GFR in Chronic Kidney Disease Patients | Observational | Actual 0 | ||
NCT03383198 | Terminated | Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine for Breast Surgery | Phase 4 | Interventional | Early termination due to manufacturer discontinued supplying the product for the study. | Actual 5 |
NCT04274933 | Terminated | A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy | Phase 1 | Interventional | Company Decision | Actual 4 |
NCT02747238 | Terminated | Does Ultrasound Help Junior Anesthesia Residents With Placement of Labor Analgesia in Pregnant Patients | N/A | Interventional | lack of enrollment | Actual 32 |
NCT02757391 | Terminated | CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors | Phase 1 | Interventional | Study halted prematurely and will not resume; participants are no longer being examined or receiving intervention. | Actual 1 |
NCT02981017 | Withdrawn | Improvement of Outcomes in Draf III/Endoscopic Modified Lothrop Procedure | N/A | Interventional | Decided to do a different clinical trial opportunity. | Actual 0 |
NCT03493412 | Withdrawn | Effects of Tetrahydrobiopterin (BH4) on Leg Blood Flow and Exercise Capacity in Patients With Peripheral Artery Disease | Phase 4 | Interventional | discontinued due to change in operating plans prior to study initiation and enrollment | Actual 0 |
NCT03744832 | Suspended | Point of Care Streptococcal Pharyngitis Testing | N/A | Interventional | The study was stopped secondary to the research curtailment and reallocation of testing resources secondary to the COVID-19 pandemic. | Actual 145 |
NCT03974152 | Suspended | Effects of Nicotine Salt Aerosol on Cigarette Smokers | N/A | Interventional | COVID concerns | Anticipated 15 |
NCT04257357 | Withdrawn | Supervised Exercise Following Pulmonary Embolism | N/A | Interventional | Due to Covid-19 pandemia the study was never initiated | Actual 0 |
NCT04581070 | Terminated | The COVID-IYON Study - Study Examining Data Pertaining to Clinical Outcomes and Organisational Responses to the 2020 SARS-CoV-2 Pandemic" | Observational | Study stopped due to low accrual | Actual 4 | |
NCT03340103 | Withdrawn | Early Administration of the Lutein/Zeaxanthin in Premature Newborns | N/A | Interventional | Recruitment was not possible | Actual 0 |
NCT04347889 | Withdrawn | Preventing COVID-19 in Healthcare Workers With HCQ: A RCT | Phase 2 | Interventional | Evidence that HCQ ineffective, loss of HCW interest, | Actual 0 |
NCT04140734 | Suspended | Spacer Graft Study | N/A | Interventional | Study has expired with the IRB | Anticipated 100 |
NCT04220632 | Terminated | A Study of IBI377 in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease | Phase 1/Phase 2 | Interventional | Adverse events of the first patient | Actual 1 |
NCT04342897 | Terminated | A Study of LY3127804 in Participants With COVID-19 | Phase 2 | Interventional | Trial terminated for futility. | Actual 95 |
NCT04363866 | Withdrawn | Assessing Hydroxychloroquine in Patients With SARS-CoV-2 (COVID-19) | Phase 2 | Interventional | discontinued in favor of more promising directions that may benefit patients | Actual 0 |
NCT03598140 | Terminated | Sildenafil Treatment for Mild TBI | Phase 2 | Interventional | PI, Dr. Josh Gaston, left the institution and the study has been stopped. | Actual 22 |
NCT04613102 | Withdrawn | The Efficacy and Safety of 3% Cannabidiol (CBD) Cream in Patients With Epidermolysis Bullosa: A Phase II/III Trial | Phase 2/Phase 3 | Interventional | The study protocol will be updated (major updates), following Health Canada request | Actual 0 |
NCT00336154 | Withdrawn | Study to Evaluate the Efficacy of Tetracycline in Epidermolysis Bullosa | Phase 4 | Interventional | Actual 0 | |
NCT03731702 | Withdrawn | Optimization of Collection Methods for Studies of the Human Microbiota | Observational | Deemed not human subjects research | Actual 0 | |
NCT03937791 | Terminated | Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions | Phase 2 | Interventional | All analysis with identifiable specimens/data is complete or site has no identifiers linked to the specimens/data. The one enrolled pt has been taken off study | Actual 1 |
NCT04606810 | Terminated | Measuring the Impact of an Innovative Educational Intervention in Inflammatory Arthritis | N/A | Interventional | Difficulties at recruiting enough participants for this study | Actual 112 |
NCT00895024 | Terminated | Caregiver Assessments of the Quality of Home Hospice Care | Observational | PRMS No Slow Accrual | Actual 74 | |
NCT03601247 | Suspended | Silicone Gel for Postsurgical Scars of the Eyelid | N/A | Interventional | The principal investigator suspended the study temporarily because of the COVID pandemic. We do not want patients to attend their follow-up visits at this time unless absolutely necessary. | Anticipated 100 |
NCT03605589 | Suspended | Pembro + Blina Combination in Pediatric and Young Adult Patients With Relapsed/Refractory Acute Leukemia or Lymphoma | Phase 1 | Interventional | Slow recruitment. Amendment pending | Anticipated 24 |
NCT04030351 | Terminated | Effect of Dried Fruit Intake on Acid-base Balance | N/A | Interventional | Institution shut down due to COVID-19 | Actual 109 |
NCT04034381 | Suspended | Dietary Intake, Health and Micronutrient Status in Haiti | Observational | Study suspended due to civil unrest and corresponding safety concerns and logistical challenges. | Anticipated 1290 | |
NCT04127721 | Withdrawn | Itacitinib for the Prevention of Graft Versus Host Disease in Patients Undergoing Donor Stem Cell Transplantation | Phase 2 | Interventional | 0 ACTUAL Enrollment must have Overall Recruitment Status | Actual 0 |
NCT00206375 | Terminated | Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidism | Phase 4 | Interventional | Actual 16 | |
NCT02885051 | Terminated | Evaluation of Pain in Preterm Newborn | N/A | Interventional | At the end of the inclusion period, the observed correlations were much lower than expected. Thus, it did not seem relevant to prolong the inclusions. | Actual 91 |
NCT03054870 | Terminated | A Comparison of Technegas and Xenon-133 Planar Lung Imaging in Subjects Referred for Ventilation Scintigraphy | Phase 3 | Interventional | Trial met primary efficacy endpoint target. No additional subjects necessary. | Actual 226 |
NCT02730962 | Terminated | Interventional Bioremediation of Microbiota in Metabolic Syndrome | Phase 2 | Interventional | Delays in IND approval caused a lack of funding to conduct the trial. | Actual 12 |
NCT04138485 | Withdrawn | Efficacy and Safety of IgPro10 in Adults With Systemic Sclerosis (SSc) | Phase 2 | Interventional | Due to business reasons, not safety issues | Actual 0 |
NCT04364009 | Suspended | Anakinra for COVID-19 Respiratory Symptoms | Phase 3 | Interventional | Efficiency and safety reasons | Actual 71 |
NCT04603963 | Terminated | Inspiratory Muscle Training in Patients With COVID 19 | N/A | Interventional | There was a change in the institutional flow reducing the cases of covid 19 | Actual 55 |
NCT00506779 | Terminated | Gleevec/Taxol for Patients With Uterine Papillary Serous Carcinoma | Phase 1/Phase 2 | Interventional | the study was terminated early due to poor enrollment | Actual 17 |
NCT02208271 | Suspended | A Validated Necrosis Assay to Determine the Need for Revision Surgery in Metal-on-metal Total Hip Arthroplasty | Observational | The lab was acquired by another company and has put this study's samples on hold. | Actual 174 | |
NCT02530502 | Terminated | Radiation Therapy With Temozolomide and Pembrolizumab in Treating Patients With Newly Diagnosed Glioblastoma | Phase 1 | Interventional | The protocol was amendment to be stopped after phase I (phase 2 removed from protocol) | Actual 4 |
NCT03176498 | Suspended | Human Umbilical Cord Mesenchymal Stem Cell Therapy for Cerebral Infarction Patients in Convalescent Period. | Phase 1/Phase 2 | Interventional | Others | Anticipated 40 |
NCT03180450 | Suspended | The Study of Heart Failure With Human Umbilical Cord Mesenchymal Stem Cells (hUC-MSC) | Phase 1/Phase 2 | Interventional | Others | Anticipated 60 |
NCT03180463 | Suspended | The Study of Early Stage Osteonecrosis of Femoral Head With Human Umbilical Cord Mesenchymal Stem Cells | Phase 1/Phase 2 | Interventional | Others | Anticipated 30 |
NCT03184935 | Suspended | Research for Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Myelodysplastic Syndrome (MDS) | Phase 1/Phase 2 | Interventional | Others | Anticipated 40 |
NCT03186456 | Suspended | The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Acute Cerebral Infarction | Phase 1 | Interventional | Others | Anticipated 40 |
NCT03569150 | Withdrawn | Culturally-Adapting a Communication Intervention to Improve Palliative Care Literacy on Two Native American Reservations | N/A | Interventional | Study not funded. | Actual 0 |
NCT03619746 | Terminated | Point-of-Care Ultrasound Educational Initiative for Insect Bites | N/A | Interventional | Lack of accrual. We were unable to enroll enough participants to have meaningful results. | Actual 71 |
NCT03816852 | Suspended | The Safety and Efficiency Study of Mesenchymal Stem Cell in Premature Ovarian Insufficiency | Phase 2 | Interventional | Others | Anticipated 12 |
NCT04058977 | Withdrawn | Redefining Survivorship: POWER to Maximize Physical Function for Survivors of Critical Illness | Phase 1/Phase 2 | Interventional | Withdrawn prior to participant enrollment due to funding status | Actual 0 |
NCT04088903 | Withdrawn | Study of Daratumumab for Decreasing Circulating Antibodies in Sensitized Patients Awaiting Heart Transplantation | Phase 1 | Interventional | Protocol changed to use subcutaneous rather than intravenous daratumumab. | Actual 0 |
NCT04163913 | Withdrawn | Radial Medical - GAPS | N/A | Interventional | Insufficient funding | Actual 0 |
NCT04250740 | Suspended | The Morning Coffee Study | N/A | Interventional | Due to COVID-19 this research needed to pause in March 2020. We plan to start the study again when we have approval to do so. | Anticipated 30 |
NCT04315155 | Withdrawn | Evaluating Safety & Efficacy Belinostat Combo w Nivo Alone & w Ipi in Patients w Treated Metastatic/Advanced Carcinomas w ARID1A Lof Mutation | Phase 1 | Interventional | study abandoned for funding issues | Actual 0 |
NCT04360876 | Withdrawn | Targeted Steroids for ARDS Due to COVID-19 Pneumonia: A Pilot Randomized Clinical Trial | Phase 2 | Interventional | Funding not received | Actual 0 |
NCT04610879 | Terminated | Changing Agendas on Sleep, Treatment and Learning in Epilepsy | Phase 4 | Interventional | Following the internal pilot, the study did not meet prespecified stop/go criteria for continuation. | Actual 5 |
NCT03621787 | Terminated | Assessing the Safety and Efficacy of a Novel Subcutaneous Implant Insertion Device on Healthy Adults | N/A | Interventional | Expiration of study funds. | Actual 9 |
NCT04344288 | Terminated | Corticosteroids During Covid-19 Viral Pneumonia Related to SARS-Cov-2 Infection | Phase 2 | Interventional | Competent Authority's decision | Actual 11 |
NCT04602884 | Suspended | Early Detection of COVID-19 Using Breath Analysis | N/A | Interventional | no additional parcipitants could be recruited at site. | Actual 50 |
NCT02243397 | Suspended | Molecular and Cellular Analysis of Breast Cancer | Observational | Safety | Anticipated 500 | |
NCT03084861 | Terminated | A Clinical Trial to Asses Efficacy and Safety of Cord Blood Eye Drops in Neurotrophic Keratopathy | Phase 1/Phase 2 | Interventional | Low recruitment. No safety issue associated. | Actual 9 |
NCT02790736 | Suspended | Brief Intervention to Reduce Fear of Public Speaking | Phase 4 | Interventional | COVID-19 restrictions | Actual 6 |
NCT03349476 | Suspended | Model Based Fast Anatomical Mapping | N/A | Interventional | study to reopen with additional enrollment | Anticipated 150 |
NCT03499353 | Terminated | Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer | Phase 2 | Interventional | This study was terminated based on Pfizer's change in clinical development strategy not related to safety and efficacy. | Actual 61 |
NCT03510208 | Suspended | Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery | Phase 1/Phase 2 | Interventional | Regulatory | Anticipated 23 |
NCT03630809 | Suspended | Immune Response and Potential Booster for Patients Who Have Received HER2-pulsed DC1 | Phase 2 | Interventional | Suspended for protocol revisions | Anticipated 40 |
NCT03861403 | Terminated | A Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid Tumors | Phase 1/Phase 2 | Interventional | Product development discontinued unrelated to safety. | Actual 10 |
NCT04233814 | Suspended | Safety, Tolerability and Pharmacokinetic Study of LTI-03 in Healthy Adult Subjects | Phase 1 | Interventional | pending clinical laboratory analyses | Anticipated 56 |
NCT04371406 | Withdrawn | Efficacy of Azithromycin-associated Hydroxychloroquine Therapy Given in General Practice in Early-stage Disease in COVID-19 Patients | Phase 3 | Interventional | Regulatory approvals have not been obtained | Actual 0 |
NCT00058188 | Terminated | Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation | Phase 3 | Interventional | Closed by the research committee | Actual 53 |
NCT02610335 | Terminated | Evaluation of Spinal Mobility Reeducation in Patients Treated for a Lumbar Spinal Stenosis After Epidural Infiltration | N/A | Interventional | The recruitment of participants was very difficult despite a change in the organisation. The inclusion criteria did not result in the expected number of participants, and the credits ran out. | Actual 23 |
NCT02689739 | Withdrawn | Validation of Ultrasound in Predicting a Low Lying Placenta Throughout Pregnancy | Observational | Actual 0 | ||
NCT03526536 | Terminated | Pilot: Insulin Sensitivity/Management in Hyperglycemic Patients in Perioperative Period ESRD/Non-ESRD | Phase 4 | Interventional | The study required more participants than anticipated for statistical significance. | Actual 40 |
NCT03647995 | Terminated | Probiotics in the Prevention of Antibiotic Induced Diarrhea and Clostridium Difficile Associated Diarrhea. | N/A | Interventional | Were not able to enroll enough participants due to shortage of study staff | Actual 25 |
NCT03923010 | Terminated | A Study of Itraconazole in the Management of Superficial Fungal Infections in India | Phase 4 | Interventional | Further recruitment not possible due to COVID 19 impact. Hence a decision to close study was taken at the antifungal CDT in Aug 2020. | Actual 40 |
NCT03975192 | Withdrawn | Neurostimulation for Opiate Withdrawal in the PICU | N/A | Interventional | There was no enrollment. | Actual 0 |
NCT04100083 | Withdrawn | Spironolactone for Hidradenitis Suppurativa | Phase 4 | Interventional | Lack of funding | Actual 0 |
NCT04231864 | Withdrawn | Durvalumab and Epacadostat for Treatment of Unresectable, Recurrent, or Metastatic Epstein-Barr Virus Positive Nasopharyngeal Cancer | Phase 2 | Interventional | Feasibility | Actual 0 |
NCT01897714 | Terminated | Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients | Phase 1/Phase 2 | Interventional | The study was terminated at median 46-48 months long term follow-up and mature overall survival follow-up data. | Actual 75 |
NCT02595918 | Terminated | Nivolumab in Treating Patients With High-Risk Kidney Cancer Before Surgery | Phase 1 | Interventional | Inadequate accrual rate | Actual 19 |
NCT04034927 | Suspended | Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer | Phase 2 | Interventional | Scheduled Interim Monitoring | Anticipated 170 |
NCT04567589 | Withdrawn | A Study to Evaluate Awareness and Knowledge of the Fibristal Additional Risk Minimization Measures Among Healthcare Professionals in Canada | Observational | This study was cancelled before any data collection due to business reasons. | Actual 0 | |
NCT01801878 | Withdrawn | Pilot Study of Skin Quality Improvement After Adipose-drived Stem Cell Transfer in Irradiated Breasts | N/A | Interventional | Difficulty in recruiting research subjects | Actual 0 |
NCT01898377 | Terminated | Imatinib Mesylate and Mycophenolate Mofetil for Steroid-Refractory Sclerotic/Fibrotic cGVHD in Children | Phase 2 | Interventional | New treatment option introduced for patients with the study indication | Actual 9 |
NCT02982499 | Terminated | Biomechanics of Optic Neuropathy | Observational | Principal investigator's decision due to lack of resources | Actual 10 | |
NCT03089567 | Withdrawn | Comparison of the Salivary Levels of Streptococcus Mutans in Pediatric Patients With Early Childhood Caries After the Application of Silver Diamine Fluoride or 5% Sodium Fluoride Varnish | Early Phase 1 | Interventional | Study was not conducted. No participants were enrolled | Actual 0 |
NCT03458910 | Terminated | Heart Rate Variability and Emotion Regulation | N/A | Interventional | COVID-19 increased risk of participation | Actual 193 |
NCT03735095 | Suspended | Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer | Early Phase 1 | Interventional | Analysis of Data | Anticipated 6 |
NCT03748173 | Terminated | Infasurf®(Calfactant) Aerosol for Infants With Bronchiolitis-AERO-04 | Phase 1 | Interventional | slowdown due to covid | Actual 13 |
NCT03796403 | Terminated | Bupivacaine Plus Diclofenac Versus Bupivacaine Alone for Postoperative Pain Relief in Gynecologic Cancer Patients | N/A | Interventional | Diclofenac is no longer recommend for intramuscular administration by the Medical Council of Thailand | Actual 140 |
NCT03846583 | Withdrawn | Tucatinib + Abemaciclib + Herceptin for HER2+ MBC | Phase 1 | Interventional | Study halted prematurely, prior to enrollment of first participant. | Actual 0 |
NCT03902977 | Terminated | Effect of Quilting Sutures on Post-operative Drainage After Mastectomy and/or Axillary Lymph Node Dissection | N/A | Interventional | insufficient recruitment | Actual 10 |
NCT04060888 | Withdrawn | A Study of Ustekinumab in Chinese Participants With Active Systemic Lupus Erythematosus | Phase 3 | Interventional | Pre-planned IA (global study) showed lack of efficacy in this indication. No new safety signals observed, findings consistent with known profile. | Actual 0 |
NCT04503538 | Withdrawn | Telemedicine for Early Detection of Cytokine Release Syndrome and Neurotoxicity | N/A | Interventional | Principal investigator decided not to pursue trial | Actual 0 |
NCT04567095 | Withdrawn | A Study to Evaluate Awareness and Knowledge of the Fibristal Additional Risk Minimization Measures Among Patients in Canada | Observational | This study was cancelled before any data collection due to business reasons. | Actual 0 | |
NCT02218567 | Terminated | Behavioural Problems in Huntington Disease : Analysis and Enhancement of Caregiver and Patient Experience | N/A | Interventional | inclusion difficult | Actual 12 |
NCT02403518 | Terminated | Clinical Outcomes of the Freedom Spinal Cord Stimulation (SCS) System for the Management of Chronic Back and Leg Pain | N/A | Interventional | Lack of recruitment | Anticipated 45 |
NCT02503280 | Withdrawn | The Transendocardial Autologous Cells (hMSC) or (hMSC) and (hCSC) in Ischemic Heart Failure Trial. | Phase 1/Phase 2 | Interventional | Study has never enrolled any subjects | Actual 0 |
NCT02537964 | Terminated | Effectiveness of Chlorhexidine Bathing in the Neonatal Intensive Care Unit | N/A | Interventional | funding not available | Actual 24 |
NCT02699723 | Withdrawn | Arsenic Trioxide and Itraconazole in Treating Patients With Advanced Basal Cell Cancer | Early Phase 1 | Interventional | Logistics | Actual 0 |
NCT00796107 | Terminated | A Study of R1507 in Combination With Letrozole in Postmenopausal Women With Advanced Breast Cancer | Phase 2 | Interventional | Due to the discontinuation of compound development, this study has been terminated. | Actual 6 |
NCT03177252 | Withdrawn | Scalp Block: Hemodynamic Stability and Patient Comfort In Craniotomy Patients | Phase 1 | Interventional | Investigator decided not to go forward with the trial. | Actual 0 |
NCT03603080 | Suspended | Efficacy of Pharmacotherapy to Enhance Weight Loss Following Sleeve Gastrectomy | Phase 4 | Interventional | Difficulty with enrollment and then Covid pandemic | Anticipated 110 |
NCT03675113 | Withdrawn | Effect of Upper Extremity Aerobic Exercise Training on Exercise Capacity Patients With Chronic Heart Failure | N/A | Interventional | This study was a doctorate thesis and student changed the subject of her thesis. | Actual 0 |
NCT03768115 | Withdrawn | Autologous Plasma Treatment for Severe Dry Eye Patients | Early Phase 1 | Interventional | The inclusion criteria for plasmapheresis is too stringent to get any potential subjects. | Actual 0 |
NCT03944733 | Withdrawn | Iron Status, Maternal Depressive Symptoms, and Mother-child Interactions | N/A | Interventional | The study was never started as a result of change of personnel and funding | Actual 0 |
NCT04014400 | Terminated | Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites | N/A | Interventional | We observed that using the Suprathel dressing required additional treatment of the wound and had a longer healing time than the standard of care Xeroform dressing; it did not dry the wound out properly to promote healing. | Actual 10 |
NCT04113083 | Suspended | An Observational Study for Evaluation of for the Prevalence of Cerebrotendinous Xanthomatosis (CTX) Disease | Observational | Due to COVID 19 Pandemic | Actual 22 | |
NCT04158596 | Withdrawn | Safety and Efficacy of SDX-3101 for the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) | N/A | Interventional | Covid-19 | Actual 0 |
NCT04341987 | Withdrawn | Treating Nightmares Among Domiciliary Patients | N/A | Interventional | Covid-related | Actual 0 |
NCT04467151 | Withdrawn | Administration of Anti-SARS-CoV-2 Convalescent Plasma in Hospitalized, Non-ICU Patients With COVID-19 | Phase 2 | Interventional | Did not obtain funding to proceed with study | Actual 0 |
NCT03436420 | Terminated | Gemcabene for the Treatment of Pediatric NAFLD | Phase 2 | Interventional | Terminated due to lack of efficacy and safety concerns. | Actual 6 |
NCT02022735 | Terminated | Deep Brain Stimulation Effects on Gait and Balance in Patients With Parkinson's Disease | N/A | Interventional | funding not secured | Actual 11 |
NCT02175082 | Terminated | Cycling in Parkinson's Disease | N/A | Interventional | Terminated prior to enrollment goals due to difficulty with recruiting subjects | Actual 12 |
NCT02522975 | Terminated | Biosimilar Erythropoietin in Anaemia Treatment (Correction Phase Study) | Phase 4 | Interventional | Actual 16 | |
NCT02755194 | Terminated | "Drugs in Lactation" Analysis Consortium | Observational | This infrastructure project has been taken over by another study. | Actual 68 | |
NCT03052361 | Terminated | Triage Administration of Ondansetron for Gastroenteritis in Children | Phase 2/Phase 3 | Interventional | The recruitment was much slower than expected and the COVID pandemic added new barriers to recruitment. | Actual 81 |
NCT03373877 | Terminated | Evaluation of Ruxolitinib in Combination With PU-H71 for Treatment of Myelofibrosis | Phase 1 | Interventional | Samus is focusing all of their efforts in myelofibrosis on the new oral formulation of PU-H71. | Actual 4 |
NCT03443622 | Withdrawn | Phase I Study of SC-43 Oral Solution in Subjects With Refractory Solid Tumors | Phase 1 | Interventional | Another study has been started in other country. | Actual 0 |
NCT03557684 | Suspended | Leucine for Depression Study (L-DEP) | Early Phase 1 | Interventional | COVID-19 | Anticipated 90 |
NCT03597503 | Terminated | Treatment of Impulsive Aggression (IA) in Adolescent With ADHD in Conjunction With Standard ADHD Treatment | Phase 3 | Interventional | Financial decision | Actual 186 |
NCT03779555 | Terminated | Lenalidomide Adherence in Older Adults | Observational | Principal Investigator left the university | Actual 17 | |
NCT04133480 | Withdrawn | Investigation of Cognitive Outcomes With Cannabidiol Oral Solution | Phase 4 | Interventional | The decision to withdraw the study was based on pandemic-related concerns of conducting a Phase IV study requiring multiple clinic visits when medication is commercially available. The study was withdrawn before any participants were recruited. | Actual 0 |
NCT04227626 | Withdrawn | Inpatient Closed Loop Glucose Control With the Gen 2 GlucoSTAT | N/A | Interventional | The study has not started, the device is not ready so the study will be delayed | Actual 0 |
NCT04290962 | Withdrawn | Web-Based Lifestyle Intervention for the Improvement of Health in African American Cancer Survivors | N/A | Interventional | no accrual | Actual 0 |
NCT04434040 | Suspended | Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC | Phase 2 | Interventional | Study team plans to revise one of the agents used in the treatment plan of the study. | Anticipated 40 |
NCT04153422 | Suspended | IVIG in the Treatment of Autoimmune Small Fiber Neuropathy With TS-HDS or FGFR-3 Antibodies | Phase 2 | Interventional | Recruitment not started at Loyola, PI leaving Loyola, PI may resume at next affiliating instituation. | Anticipated 20 |
NCT03197025 | Terminated | Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions | Phase 1 | Interventional | The study was closed due to investigator discretion based on the lack of perceived clinical activity observed in the study. | Actual 1 |
NCT04600648 | Withdrawn | Sweet Taste Responsiveness in Relation to Insulin, Leptin and Adiposity Among Obese Treatment Seeking Children | N/A | Interventional | poor enrollment | Actual 0 |
NCT04270461 | Withdrawn | NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors | Phase 1 | Interventional | Study is withdrawn because of administrative reasons | Actual 0 |
NCT02660528 | Terminated | Tocilizumab Augmentation in Treatment-Refractory Major Depressive Disorder | Phase 2 | Interventional | Study staff change. | Actual 3 |
NCT02750254 | Terminated | Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation | Phase 1 | Interventional | Toxicity. Only enrolled patients in phase I portion of trial. | Actual 5 |
NCT02859428 | Terminated | Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31 | Observational | Investigator left NIH | Actual 51 | |
NCT02885987 | Withdrawn | Use of Accessory Device AmplifEYE During Average Risk Screening Colonoscopy to Increase Adenoma Detection Rate | N/A | Interventional | decided not to go ahead with study at this time | Actual 0 |
NCT02919553 | Withdrawn | Modified Wet Suction Versus Capillary Techniques for EUS Guided Fine Needle Aspiration and Biopsy of Solid Lesions | N/A | Interventional | decided not to proceed with study at this time | Actual 0 |
NCT02930122 | Terminated | IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions | Phase 2 | Interventional | Lack of funding | Actual 6 |
NCT03327987 | Withdrawn | Early Flu Shots in SOT | Observational | The study was on hold and later withdrawn due to shortage of staff | Actual 0 | |
NCT03487731 | Withdrawn | Allogeneic Human Mesenchymal Stem Cell Injection in PAtieNts With FaceTogenic Back Pain | Phase 1/Phase 2 | Interventional | PI decided to not proceed with study | Actual 0 |
NCT03508427 | Suspended | Toi Même: a Mobile System for Measuring Bipolar Illness | N/A | Interventional | Suspended since april 2020 as the application is temporarily unavailable | Anticipated 93 |
NCT02703311 | Terminated | REPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System | N/A | Interventional | Edwards acquired Valtech Cardio Ltd in 2017 and opted to replace this study with NCT03600688.11 patients were enrolled in REPAIR and follow-up is complete. | Actual 11 |
NCT03741062 | Terminated | Effects of Laser Stimulation on Wound Healing of Human Palatal Tissue | N/A | Interventional | COVID-19 | Actual 11 |
NCT00769002 | Terminated | PET-CT Scans in Healthy Volunteers After Flu Vaccination | N/A | Interventional | Actual 18 | |
NCT03376321 | Terminated | A Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Hospitalized Participants With Influenza A Infection | Phase 3 | Interventional | Study terminated early (date of study termination decision: 28 August 2020) as a result of the outcome of the pre-planned Interim Analysis. | Actual 334 |
NCT02010567 | Terminated | Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer | Phase 1/Phase 2 | Interventional | The study was halted prematurely at the funding partner's request. | Actual 32 |
NCT02452359 | Terminated | Clinical Evaluation of Using Intense Pulsed Light for Improving the Appearance of Striae Distensae | N/A | Interventional | Continuing the trial was considered to be superfluous. | Actual 54 |
NCT02452398 | Terminated | Clinical Evaluation of Hair Removal and Permanent Hair Reduction for Skin Types VI Using Intense Pulsed Light | N/A | Interventional | Study withdrawn as technology already proven with data no longer needed. | Actual 79 |
NCT03259425 | Terminated | Neoadjuvant Trial of Nivolumab in Combination With HF10 Oncolytic Viral Therapy in Resectable Stage IIIB, IIIC, IVM1a Melanoma | Phase 2 | Interventional | DSMC Recommendation | Actual 7 |
NCT03819504 | Withdrawn | Stereotactic Non-invasive Ablation of Ventricular Tachycardia | N/A | Interventional | Change in the design of the study | Actual 0 |
NCT04589897 | Suspended | Manuka Honey Sinus Rinse Study | N/A | Interventional | Paused for Covid-19 | Anticipated 40 |
NCT04591288 | Terminated | FES to Improve Gait in CP | N/A | Interventional | Closed by the sponsor for not fully meeting subject recruitment targets. | Actual 2 |
NCT01938716 | Terminated | Gemcitabine Pharmacokinetics After Preoperative Chemoradiation Therapy | N/A | Interventional | Early termination due to low accrual | Actual 12 |
NCT00759083 | Withdrawn | Bivalirudin PCI Registry in Heparin Induced Thrombocytopenia/Heparin Induced Thrombocytopenia and Thrombosis Syndrome (HIT/HITTS) Patients | Phase 4 | Interventional | The study was discontinued early due to inadequate patient enrollment. No patients were enrolled. | Actual 0 |
NCT01003795 | Withdrawn | Promus - Registry Experience at the Washington Hospital Center, Drug-eluting Stent (DES) | Observational | Not Funded | Actual 0 | |
NCT01806064 | Terminated | Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone in Patients Renal Cell Carcinoma | Phase 1/Phase 2 | Interventional | The study did not meet endpoint. | Actual 173 |
NCT02100735 | Withdrawn | Evaluation of an Analgosedation Protocol in Mechanically Ventilated Patients | N/A | Interventional | Difficulty in with enrollment of patient | Actual 0 |
NCT02354144 | Terminated | Lubricant Investigation in Men to Inhibit Transmission of HPV Infection | Phase 2/Phase 3 | Interventional | Mandated by DSMB because of lack of protective effect of carrageenan, higher proportion of adverse events in the carrageenan compared to placebo arm, and low probability that continued accrual would lead to a significant protective effect. | Actual 258 |
NCT02607124 | Terminated | A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy | Phase 1/Phase 2 | Interventional | A competing trial was opened for patient population with combination of ribociclib and everolimus. | Actual 11 |
NCT02642939 | Terminated | Study of Oral Mifepristone as Salvage Therapy in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer | Phase 2 | Interventional | Lack of enrollment | Actual 3 |
NCT03008772 | Withdrawn | REWARDS- In-stent Restenosis | Observational [Patient Registry] | Not funded | Actual 0 | |
NCT03037645 | Terminated | Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers | Phase 1/Phase 2 | Interventional | Phase 1b portion completed. Sponsor decided not to proceed with P2 portion of study. Vecabrutinib was very well tolerated, there was insufficient evidence of activity at the doses tested in the Phase 1b to advance to Phase 2. | Actual 39 |
NCT03273257 | Terminated | Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study) | Phase 2 | Interventional | The study was stopped due to slower than expected recruitment and the additional limitations on clinical research imposed by the COVID-19 pandemic, both of which made study completion within a reasonable timeframe appear unlikely. | Actual 14 |
NCT03682055 | Terminated | Phase 1/2a Study of VK-2019 in Patients With Epstein-Barr Virus (EBV)-Positive Nasopharyngeal Carcinoma (NPC) | Phase 1/Phase 2 | Interventional | Lack of efficacy | Actual 14 |
NCT03800420 | Terminated | Efficacy and Safety of BBT-401-1S in Ulcerative Colitis | Phase 2 | Interventional | to carry out the rest of the study with new CRO and modified protocol as a multi-regional study. | Actual 16 |
NCT03945331 | Terminated | Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans With Motor Complete Paraplegia | N/A | Interventional | COVID-19 disrupted interventions irrecoverably. | Actual 2 |
NCT04106050 | Withdrawn | Pharmacodynamic Study of BIIB095 and BIIB074 in Healthy Participants and Participants With Painful Diabetic Polyneuropathy | Phase 1 | Interventional | Sponsor Decision | Actual 0 |
NCT04323969 | Terminated | Gait Modification for Knee Osteoarthritis | N/A | Interventional | COVID-related laboratory shutdown. | Actual 3 |
NCT00927108 | Withdrawn | Rajavtihi Neuronal Adult Stem Cells Project | Phase 2 | Interventional | Actual 0 | |
NCT01130324 | Withdrawn | VIBATIV Pregnancy Registry | Observational [Patient Registry] | Released by he FDA from this Post-Marketing Commitment | Actual 0 | |
NCT02363647 | Suspended | Personalized Cancer Therapy for Patients With Metastatic Medullary Thyroid or Metastatic Colon Cancer | N/A | Interventional | No Current Funding | Actual 10 |
NCT02595996 | Terminated | Propranolol Dose Escalation in Lymphedema in Patients | Phase 2 | Interventional | Lack of funding | Actual 1 |
NCT02965508 | Terminated | Home-based Primary Care for Homebound Seniors | N/A | Interventional | The Data Safety Monitoring Board determined that the serious adverse event rate was higher among patients awaiting enrollment in the home-based primary care intervention compared to those who had initiated home-based primary care. | Actual 230 |
NCT03110588 | Withdrawn | Phase I Trial of PACE for Metastatic Prostate Cancer | Phase 1 | Interventional | PI left the institution | Actual 0 |
NCT03264092 | Terminated | Comparison of Three Tissue Acquiring Techniques During EUS Guided Biopsies of Solid Tumors. | N/A | Interventional | Preliminary analysis of the results showed no statistically significant difference | Actual 54 |
NCT03625336 | Withdrawn | MR Imaging of Prostatic Calcifications | Observational | study on hold for an undetermined time | Actual 0 | |
NCT03945227 | Withdrawn | Clinical Trial for Evaluating Efficacy and Safety of PDR001 in Concurrent Plus Consolidation Versus Consolidation Only in Addition to Standard Chemoradiotherapy in Unresectable Stage III NSCLC Patients (PASTURE) | Phase 2 | Interventional | Due to the delay in the study shceduled, due to the start of competitive study and the approval of Durvalumab from the Ministry of Food and Drug Safety, it was judged that it was difficult to enroll subjects. | Actual 0 |
NCT04426344 | Withdrawn | Core Warming of COVID-19 Patients | N/A | Interventional | Internal decision | Actual 0 |
NCT02064959 | Terminated | To Study the Effect of Early Cooling in Acute Subdural Hematoma Patients | N/A | Interventional | interim analysis revealed it was futile, we would not reach an answer at N=60. | Actual 32 |
NCT03567694 | Suspended | Single and Multiple Doses of HA115 and Food Effect in Healthy Adult Volunteers | Phase 1 | Interventional | Business decision | Anticipated 120 |
NCT00004026 | Terminated | CT-2584 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Previous Therapy | Phase 2 | Interventional | Anticipated 80 | |
NCT00551239 | Withdrawn | Fludarabine and Rituximab With or Without Pixantrone in Treating Patients With Relapsed or Refractory Indolent Non-Hodgkin Lymphoma | Phase 3 | Interventional | Actual 0 | |
NCT02425878 | Terminated | Ulipristal Acetate 10 mg and Asisted Reproduction | Phase 3 | Interventional | Lack of availibility of eligible subjects | Actual 2 |
NCT03203993 | Terminated | China Ovarian Cancer BRCA Testing Study | Observational | Failure to obtain HGR approval. | Actual 29 | |
NCT02876094 | Terminated | Effect of Low-Dose Celecoxib on SMN2 in Patients With Spinal Muscular Atrophy | Phase 2 | Interventional | Terminated: Study halted prematurely and will not resume; participants are no longer being examined or receiving intervention | Actual 1 |
NCT02946346 | Terminated | Kinetics and Ecology of Human Papillomavirus Genital Infections in Young Women | N/A | Interventional | Difficulty to continue follow-up during the coronavirus epidemic | Actual 190 |
NCT03449160 | Withdrawn | Postural Training Device (UPRIGHT) for Back Pain | N/A | Interventional | COVID 19 which is preventing outpatient and elective procedures | Actual 0 |
NCT03484962 | Withdrawn | Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Liver Cancer | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT01118715 | Terminated | Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial | N/A | Interventional | Impractical to enroll the #s needed for statistical significance; project manager relocated | Actual 128 |
NCT03501056 | Withdrawn | Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Lung Cancer | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT03509298 | Withdrawn | Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Pancreatic Cancer | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT03524261 | Withdrawn | Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Breast Cancer | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT03524274 | Withdrawn | Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Colorectal Cancer | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT03540199 | Withdrawn | Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Kidney Cancer | Phase 2 | Interventional | No participant enrolled | Actual 0 |
NCT03554395 | Withdrawn | Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Gastric Cancer | Phase 2 | Interventional | No participants enrolled | Actual 0 |
NCT04333628 | Terminated | Chloroquine for Mild Symptomatic and Asymptomatic COVID-19 | Phase 2/Phase 3 | Interventional | Teminated due to changes in treatment guidelines . | Actual 5 |
NCT03793686 | Terminated | A Study of Safety of PBCLN-003 Following Antibiotic Therapy in Subjects With C.Difficile-associated Diarrhea | Phase 1 | Interventional | Unable to enroll subjects | Actual 26 |
NCT03796416 | Withdrawn | Obesity Study to Assess Induction of Labor | N/A | Interventional | in error | Actual 0 |
NCT03871400 | Suspended | The NanoStrand Clinical Study | N/A | Interventional | Study halted prematurely and will not resume; participants are no longer receiving intervention due to coronavirus pandemic and unexpected enrollment delays. | Actual 18 |
NCT03963024 | Terminated | Treosulfan-TMI Conditioning and Rapamycin GvHD Prophylaxis Before Allo-HSCT | Phase 1 | Interventional | low rate of enrolment | Actual 9 |
NCT03973021 | Withdrawn | Very Small Embryonic-like Stem Cells for Erectile Dysfunction | Phase 1/Phase 2 | Interventional | Policy changes have contributed to the failure to carry out smoothly | Actual 0 |
NCT03975101 | Withdrawn | Very Small Embryonic-like Stem Cells for Knee Osteoarthritis | Phase 1/Phase 2 | Interventional | Policy changes have contributed to the failure to carry out smoothly | Actual 0 |
NCT03976206 | Withdrawn | Very Small Embryonic-like Stem Cells for Facial Skin Antiaging | Phase 1/Phase 2 | Interventional | Policy changes have contributed to the failure to carry out smoothly | Actual 0 |
NCT03985462 | Withdrawn | Very Small Embryonic-like Stem Cells for Ovary | Phase 1/Phase 2 | Interventional | Policy changes have contributed to the failure to carry out smoothly | Actual 0 |
NCT04058301 | Suspended | Text-Enabled Ascertainment and Community Linkage for Health | N/A | Interventional | COVID-19 | Anticipated 200 |
NCT04165668 | Terminated | Wellbeing and Stress Among Mobile Phone Dispatched Lay Responders | Observational | Due to the COVID-19 Pandemic. | Actual 460 | |
NCT04234581 | Terminated | The Effect of Lysulin on Glycemic Control and Advanced Glycation | N/A | Interventional | Sponsor decision | Actual 59 |
NCT04388189 | Withdrawn | Leveraging EEG for Antidepressant Prediction With Duloxetine and Bupropion | Phase 4 | Interventional | No participants enrolled | Actual 0 |
NCT04388202 | Withdrawn | Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram | Phase 4 | Interventional | No participants enrolled | Actual 0 |
NCT04516603 | Withdrawn | Influence of Fampridine on Working Memory in Healthy Subjects | Phase 2 | Interventional | Changement of study design. Restart spring 2021. | Actual 0 |
NCT01601496 | Terminated | Evaluation of FUSION™ Vascular Graft for Above Knee Targets | N/A | Interventional | Slow Enrollment | Actual 117 |
NCT02547376 | Terminated | Genetic and Telomere Characteristics of High of Grade Soft Tissue Sarcomas | Observational | Covid-19 | Actual 77 | |
NCT02812849 | Withdrawn | Somatostatin Receptor Imaging in Cardiac Sarcoidosis | Observational | Logistic reasons | Actual 0 | |
NCT02687815 | Terminated | Vitamin D to Prevent Severe Asthma Exacerbations (Vit-D-Kids Asthma) | Phase 2 | Interventional | Futility of vitamin D supplementation based on protocol threshold: <30% conditional power to detect pre-specified effect- 16% reduction in severe exacerbations. | Actual 192 |
NCT02843568 | Suspended | Improving Pulmonary Function Following Radiation Therapy | N/A | Interventional | Administrative suspension at the request of the Director, Office of Industry Engagement | Anticipated 120 |
NCT02941016 | Withdrawn | Vascular Inflammation and Cholesterol Lowering Therapy | Phase 4 | Interventional | Logistic reasons | Actual 0 |
NCT03259308 | Terminated | Efficacy and Safety Study of SHP647 as Induction Therapy in Participants With Moderate to Severe Ulcerative Colitis | Phase 3 | Interventional | Sponsor decision to discontinue the SHP647 (ontamalimab) clinical trial development program for inflammatory bowel diseases (IBD) early. | Actual 279 |
NCT03342859 | Terminated | Mode of Action Study of Vilaprisan and Ulipristal Acetate in Patients With Uterine Fibroids for Whom Surgery is Planned | Phase 1 | Interventional | Due to findings in the preclinical carcinogenicity studies for vilaprisan (BAY1002670) | Actual 10 |
NCT03697954 | Withdrawn | Direct Full-stage Implantation of Sacral Neuromodulation | Observational | Work has already been published by other groups | Actual 0 | |
NCT04085978 | Terminated | Effects of a Hypoglycemia Protocol With Glucose Gel on Neonatal Intensive Care Unit (NICU) Admission | Observational | The standard of care had changed during our wait for the Program Letter of Agreement between Phoenix Children's Hospital and Banner to administering IV glucose in the newborn nursery so we weren't able to meet our objective. | Actual 400 | |
NCT04246411 | Withdrawn | Ultrasound vs. Auscultation for Optimal Depth of the Cuffless RAE Tube | N/A | Interventional | It was confirmed that cuffed RAE tubes with small diameter could be used, so there was no reason to use RAE cuffless tubes. | Actual 0 |
NCT04335071 | Terminated | Tocilizumab in the Treatment of Coronavirus Induced Disease (COVID-19) | Phase 2 | Interventional | 1.) Not possible to recruit the planned number of patients during the planned study period; 2.) "Dexamethason" was included in the standard of care for the study population during the course of the study and inclusion criteria could no longer be met. | Actual 5 |
NCT04462757 | Suspended | SCIL-1Ra in COVID-19 Feasibility & PK/PD | Phase 2 | Interventional | Lack of patients in the trial population from which to recruit and lack of funding | Actual 5 |
NCT03122470 | Withdrawn | Correlation of Imaging Findings With Clinical Findings and Patient Outcomes in Prostate Cancer | N/A | Interventional | PI departure - study not conducted. | Actual 0 |
NCT04519424 | Withdrawn | CSL324 in COVID-19 | Phase 2 | Interventional | Due to business reasons, not safety issues. | Actual 0 |
NCT04592380 | Withdrawn | Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF | Phase 3 | Interventional | Product was divested to Chiesi USA, who decided to not move forward with study. | Actual 0 |
NCT02611128 | Suspended | Urinary DENND1A.V2 as a Predictor of Pubertal Hyperandrogenemia | Observational | temporarily closed to enrollment due to COVID | Anticipated 65 | |
NCT02701322 | Terminated | Influence of Medical Clowning in Videofluoroscopic Examination of Pediatric Speech Disorder | N/A | Interventional | machine malfunction and updated work rutines | Actual 10 |
NCT03604523 | Terminated | Esophageal Dysmotility - Prospective Study Evaluating Methods for Esophageal Dilation | N/A | Interventional | Slow enrollment | Actual 10 |
NCT03763175 | Terminated | Efficacy and Safety of SYN-010 in IBS-C | Phase 2 | Interventional | Interim Futility Analysis | Actual 59 |
NCT04585022 | Terminated | Whole Blood Metal Ion Concentrations in Metal-on-metal Total Hip Arthroplasty and Hip Resurfacing | N/A | Interventional | High early failure rates and adverse reactions in similar devices | Actual 75 |
NCT01863498 | Terminated | Prospective Trial: Pain Management After Pectus Excavatum Repair, Epidural Versus PCA | N/A | Interventional | Institution converted to an alternative strategy for pain control | Actual 65 |
NCT03515941 | Terminated | Postoperative Chemoradiation or Chemotherapy After Preoperative Chemotherapy for Gastric Cancers | Early Phase 1 | Interventional | The PI has decided to close the study due to the outdated study design. | Actual 6 |
NCT04128020 | Withdrawn | Azacitidine Plus Nivolumab Following Reduced-intensity Allogeneic PBSC Transplantation for Patients With AML and High-risk Myelodysplasia | Phase 1 | Interventional | Funder withdrew funding after not accruing any subjects after 1 year. | Actual 0 |
NCT04460105 | Withdrawn | Lanadelumab in Participants Hospitalized With COVID-19 Pneumonia | Phase 1 | Interventional | Study was withdrawn due to challenges in site recruitment and lack of patient enrollment | Actual 0 |
NCT00538681 | Terminated | Study for Participants With Advanced, Not Amenable to Surgery, or Metastatic Lung Cancer Comparing Treatment With Pemetrexed + Cisplatin + Enzastaurin Versus Pemetrexed + Cisplatin + Placebo | Phase 2 | Interventional | Terminated due to lack of efficacy demonstrated in relevant participant population in other clinical trials. | Actual 35 |
NCT02824211 | Withdrawn | Demonstrating the Feasibility of a Novel Oxygen Delivery Device | N/A | Interventional | Was unable to obtain funding | Actual 0 |
NCT02907918 | Terminated | Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer | Phase 2 | Interventional | Futility | Actual 26 |
NCT03013127 | Terminated | A Study of Pembrolizumab in Patients With Relapsed Or Metastatic Osteosarcoma Not Eligible for Curative Surgery | Phase 2 | Interventional | Inclusion of patients was stopped because ≤2 patients had clinical benefit. | Actual 12 |
NCT03056508 | Terminated | Lifestyle, Exercise and Diet: The LEAD Study | N/A | Interventional | Due to COVID-19, recruitment and enrollment was suspended and never resumed. COVID-related changes have been made to the clinical program which houses our intervention, and we could not compare new participants with our previous cohort. | Actual 14 |
NCT03636373 | Suspended | Pilot Study Evaluating The Efficacy Of Etanercept In Acute Gout | Phase 4 | Interventional | Temporarily paused due to COVID 19 and expected to resume | Anticipated 40 |
NCT03886493 | Terminated | Neoadjuvant Dupilumab in Men With Localized High-Risk Prostate Cancer | Phase 2 | Interventional | Low accrual due to COVID-19 pandemic. | Actual 7 |
NCT03947203 | Withdrawn | Oral Health Promotion: Youth as Agents Of Change | N/A | Interventional | Unable to staff the project | Actual 0 |
NCT03992716 | Terminated | Reaching Protein Target With SmofKabiven® Extra Nitrogen vs Olimel N9E During the Early Phase of Acute Critical Illness | Phase 4 | Interventional | Study had to be put on hold after the outbreak of Covid-19 in the participating countries and was terminated in September 2020 since a date for re-starting was not foreseeable. | Actual 7 |
NCT04129320 | Withdrawn | Enoblituzumab Plus MGA012 or MGD013 in Squamous Cell Carcinoma of the Head and Neck | Phase 2/Phase 3 | Interventional | Change in study design | Actual 0 |
NCT04212065 | Withdrawn | Long Acting Subcutaneous vs Short Acting Sublingual Buprenorphine in Pregnant and Lactating Women | Phase 4 | Interventional | closed due to new safety concerns of subcutaneous buprenorphine in pregnant patients | Actual 0 |
NCT03891641 | Terminated | Momentum-enabled Treadling Methodology to Improve Gait and Enhance Mobility | N/A | Interventional | COVID-19 continues to prevent recruitment of people over the age of 65 years. | Actual 17 |
NCT02152670 | Terminated | Understanding Dopamine Mechanisms in Cocaine Addiction Using AMPT and Methylphenidate With [11C]RAC/[11C]PHNO PET | N/A | Interventional | Study drug became unaffordable for the purposes of the research. | Actual 1 |
NCT04322773 | Terminated | Anti-il6 Treatment of Serious COVID-19 Disease With Threatening Respiratory Failure | Phase 2 | Interventional | The study has been terminated due to changed clinical conditions and too few patients available | Actual 20 |
NCT01244191 | Terminated | Tivantinib Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous, Non-small-cell Lung Cancer | Phase 3 | Interventional | Sponsor decision due to the protocol-defined stopping boundary for futility was met based on the interim OS data. | Actual 1048 |
NCT04581564 | Suspended | Rhythm-based Intervention in Aphasia | Early Phase 1 | Interventional | Due to COVID-19 | Anticipated 20 |
NCT02438371 | Terminated | Nifedipine or Nifedipine Plus Indomethacin for Treatment of Acute Preterm Labor | Phase 4 | Interventional | Study halted due to slow recruitment | Actual 37 |
NCT02285283 | Terminated | Itraconazole for Fungal Sensitive Chronic Rhinosinusitis With Nasal Polyps | Phase 2/Phase 3 | Interventional | Recruitment failure. | Actual 58 |
NCT02455817 | Withdrawn | REWARDS-Angina at Follow up Post Stenting | Observational | Actual 0 | ||
NCT02630355 | Terminated | Remote Ischaemic Preconditioning to Prevent Dialysis Induced Cardiac Injury | Phase 2 | Interventional | The study was terminated prematurely after ad-interim analysis for the primary outcome. | Actual 32 |
NCT03547206 | Terminated | Efficacy & Safety of RPh201 Treatment in Patients With Previous Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) | Phase 2 | Interventional | Terminated by Sponsor | Actual 165 |
NCT03786380 | Terminated | Diabetic Gastroparesis Study 05 | Phase 3 | Interventional | The Relamorelin program is being terminated solely based on a business decision. | Actual 202 |
NCT03850535 | Terminated | A Study Evaluating the Safety and Efficacy of Idasanutlin in Combination With Cytarabine and Daunorubicin in Patients Newly Diagnosed With Acute Myeloid Leukemia (AML) and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete Remission | Phase 1/Phase 2 | Interventional | Sponsor's decision to terminate the study after Phase 1; will not proceed with Phase 2. | Actual 24 |
NCT03947814 | Terminated | A Study of Orally Administered Pimodivir in Adult Participants With Renal Impairment | Phase 1 | Interventional | Strategic decision to stop pimodivir phase 1 studies | Actual 29 |
NCT04264533 | Terminated | Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia | Phase 2 | Interventional | the study was started in the second half of the outbreak, and the number of qualifying COVID-19 patients decreased with the control of the epidemic so that we had to stop our trial before reaching the predefined sample size. | Actual 56 |
NCT04089761 | Terminated | Safety and Efficacy of Nerivio™ for the Acute Treatment of Migraine in Adolescents | N/A | Interventional | Due to the outbreak of the COVID-19 pandemic in the USA on March 2020, all study sites stopped enrolling patients to the study | Actual 60 |
NCT04280068 | Terminated | Targeting Non-virally Suppressed Adults With Alcohol Use Disorder in HIV Primary Care | N/A | Interventional | Due to COVID-19 recruitment and enrollment of participants was halted | Actual 3 |
NCT04311112 | Suspended | Safety and Efficacy of Zuretinol Acetate in Subjects With Inherited Retinal Disease | Phase 2/Phase 3 | Interventional | Company dissolved | Anticipated 45 |
NCT03027401 | Withdrawn | Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics | Observational | closed by PI and FDA | Actual 0 | |
NCT03788486 | Withdrawn | Efficacy and Safety of Meibomian Gland Dysfunction and Dry Eye With an LED Blue Treatment Device | N/A | Interventional | Covid | Actual 0 |
NCT03827564 | Terminated | Goblet Cell Degranulation Produced by Intranasal Tear Neurostimulator (ITN) in Dry Eye Disease | N/A | Interventional | Study discontinued due to business reasons. | Actual 14 |
NCT04007926 | Suspended | Mechanisms of Insulin Resistance and Exercise in South Asians | N/A | Interventional | COVID-19 | Anticipated 66 |
NCT04010682 | Suspended | Late Pregnancy Sample Collection Study | Observational | sufficient volunteer recruited for the moment. Study may be re-opened at a later date | Anticipated 40 | |
NCT04088266 | Withdrawn | An Open-Label, Single-Center Study to Evaluate the Exposure-Response Relationship Between the Plasma Drug Concentrations and the Change From Baseline in QTc at Steady State Following Once-daily Administration of CASSIPA® in Opioid Dependent Subjects. | Phase 4 | Interventional | Study delayed indefinetly | Actual 0 |
NCT04464460 | Withdrawn | A Study to Evaluate the Safety, Pharmacokinetics (PK), and Efficacy of TAK-671 for the Treatment of Coronavirus Disease (COVID) 2019 in Adults | Phase 1 | Interventional | Business Decision (no enrollment) | Actual 0 |
NCT00785135 | Terminated | Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria | N/A | Interventional | Unable to recruit - multiple reasons.- inclusion/exclusion criteria too strict was th emain reason. | Actual 13 |
NCT02036502 | Terminated | A Study of Pembrolizumab (MK-3475) in Combination With Standard of Care Treatments in Participants With Multiple Myeloma (MK-3475-023/KEYNOTE-023) | Phase 1 | Interventional | Business Reasons | Actual 77 |
NCT02720341 | Terminated | VIT-ARMin Virtual, Intensified and Patient-tailored Robotic Arm Therapy With the Exoskeleton Robot ARMin | N/A | Interventional | Doctoral students on project defended their thesis. | Actual 222 |
NCT02880904 | Terminated | Vulvar Scarring Grading Scale for Lichen Sclerosus | Observational | Investigator is no longer at Northwestern University | Actual 30 | |
NCT02881229 | Terminated | Vulvar Mucosal Specialty Clinic Chart Review | Observational | Investigator is no longer at Northwestern University | Actual 719 | |
NCT03315143 | Terminated | Effect of Sotagliflozin on Cardiovascular and Renal Events in Patients With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk | Phase 3 | Interventional | study terminated prematurely for financial reasons and Covid-19 pandemic | Actual 10584 |
NCT03389893 | Terminated | Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic Dermatitis | Phase 4 | Interventional | Due to inability to meet accrual goals within the funding period. | Actual 72 |
NCT03497117 | Terminated | 19F MRI of Ventilation in Subjects With Cystic Fibrosis Undergoing Treatment for Pulmonary Exacerbation | Early Phase 1 | Interventional | Enrollment barriers made study completion impossible | Actual 5 |
NCT03521934 | Terminated | Effect of Sotagliflozin on Cardiovascular Events in Patients With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial) | Phase 3 | Interventional | study terminated prematurely for financial reasons and Covid-19 pandemic | Actual 1222 |
NCT03837418 | Withdrawn | DESIGNING A PROGRAMMING LANGUAGE FOR PATIENT-ORIENTED PRESCRIPTIONS (POP-PL) | Observational | Investigator is no longer at Northwestern University. | Actual 0 | |
NCT03921476 | Withdrawn | Acne and Mood: Impact of Treatment on Depression, Anxiety, and Sexual Function | Observational | Investigator left Northwestern University | Actual 0 | |
NCT03955471 | Suspended | Study to Evaluate the Efficacy and Safety of the Combination of Niraparib and Dostarlimab (TSR-042) in Participants With Platinum Resistant Ovarian Cancer | Phase 2 | Interventional | This study has temporarily held recruitment activities to perform a pre-planned interim analysis. Other elements of this study are still ongoing. | Anticipated 150 |
NCT04386668 | Terminated | Let It Out (LIO) and COVID19: Testing an Online Emotional Disclosure-based Intervention During the COVID19 Pandemic | N/A | Interventional | Interim analysis indicated adaptations to intervention may be required. | Actual 80 |
NCT00152308 | Terminated | Non-Polymer-Based, Rapamycin-Eluting Stents to Prevent Restenosis | Phase 4 | Interventional | Slow enrolement | Anticipated 333 |
NCT01289340 | Withdrawn | Wound Healing and Pain Management in Partial Thickness Burns | Observational | Actual 0 | ||
NCT01742273 | Terminated | Vitamin K1 to Slow Progression of Vascular Calcification in HD Patients | Phase 3 | Interventional | Termination stopped due to low recruitment rates | Actual 63 |
NCT01974726 | Terminated | Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction | N/A | Interventional | End of funding | Actual 95 |
NCT02204202 | Terminated | PET Assessment of Acute Lung Transplant Rejection | Observational | PI left institution | Actual 28 | |
NCT02402803 | Terminated | Dried Blood Spot- Statin Pilot Study | Observational | No recruitment | Actual 20 | |
NCT03012737 | Terminated | Palliation of Dyspnea With Mouth Piece Ventilation | N/A | Interventional | Difficulty in finding suitable patients. | Actual 22 |
NCT03025425 | Terminated | Palliation of Dyspnea With Mouth Piece Ventilation in AECOPD | N/A | Interventional | Difficulty in finding suitable patients | Actual 20 |
NCT03383146 | Terminated | A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis Study 04 | Phase 3 | Interventional | The Relamorelin program is being terminated solely based on a business decision. | Actual 451 |
NCT03420781 | Terminated | A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis Study 03 | Phase 3 | Interventional | The Relamorelin program is being terminated solely based on a business decision. | Actual 467 |
NCT03441334 | Terminated | rTMS Combined With BWSTT in Stroke With Body Weight Supported Treadmill Training (BWSTT) After Stroke | N/A | Interventional | The enrollment was not achieved within proposed timeframe. | Actual 1 |
NCT03499587 | Terminated | Effects of Maternal Obesity on Offspring Brain Development | Observational | study population limited | Actual 13 | |
NCT03511716 | Terminated | Observational Study of the Heart Repair Technologies Mitral Bridge in Treating Mitral Valve Regurgitation | Observational | Could not enroll enough patients and ran out of $$ to manufacture more devices | Actual 34 | |
NCT03518996 | Withdrawn | Non-Invasive Brain Stimulation and Delirium | N/A | Interventional | EEG data collection instrument unavailable | Actual 0 |
NCT03529916 | Suspended | Endothelial Cell Gene Networks of CVD | Observational | No eligible participants were recruited | Anticipated 20 | |
NCT03575494 | Withdrawn | Relationship Between Oral Health Status and Unexplained Female Infertility in Turkish Population | Observational | this study does not need to get a clinicaltrials number | Actual 0 | |
NCT03630081 | Withdrawn | Study of Cefepime-tazobactam (FEP-TAZ) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) | Phase 3 | Interventional | Change in business strategy | Actual 0 |
NCT02220855 | Suspended | A Study of BKM120 (Buparlisib) in Relapsed or Refractory Thymomas | Phase 2 | Interventional | Not stated by Pharmaceutical Company | Actual 14 |
NCT03802422 | Withdrawn | Vitamin B12 for Carpal Tunnel Syndrome | N/A | Interventional | It is hard to enroll patients due to Covid-19 pandemic. | Actual 0 |
NCT03883607 | Terminated | Elafibranor, PK and Safety in Children and Adolescents 8 to 17 Years of Age With Non Alcoholic Steatohepatitis (NASH) | Phase 2 | Interventional | Continuation of the trial cannot serve a scientific purpose, no safety concerns identified | Actual 10 |
NCT03963492 | Suspended | Intermittent vs Continuous Walking in People With Multiple Sclerosis | N/A | Interventional | COVID-19 Pandemic | Anticipated 24 |
NCT04060693 | Withdrawn | Device Accuracy of Non-invasive Glucose Measurements in Ethnic Skin | N/A | Interventional | Miscommunication with the CRO that was hired to help with the regulatory submission process | Actual 0 |
NCT04076345 | Terminated | Interest of the Presepsin Assay as a Biomarker of Bacterial Infection, in the Management of Newborns and Infants Under 3 Months of Age Admitted for Fever in Pediatric Emergency Service (Presepsin) | Observational | investigator not available | Actual 31 | |
NCT04111861 | Suspended | Singing for Chronic Pain, a New Intervention for the Management of Chronic Pain | N/A | Interventional | COVID-19 - unable to bring patients for intervention due to C-19 restrictions at present | Anticipated 24 |
NCT04146779 | Terminated | Yoga Intervention in Head and Neck Cancer Patients Undergoing Concurrent Chemo-Radiation | N/A | Interventional | COVID-19 | Actual 19 |
NCT04258020 | Suspended | Postextubation Management in Patients at Risk for Extubation Failure | N/A | Interventional | Study is on hold due to significant impact of COVID pandemic | Actual 3 |
NCT04304365 | Withdrawn | Home Follow-up After Medication Abortion | N/A | Interventional | Unable to implement the study due to delays from COVID-19 policies which postponed the start. | Actual 0 |
NCT00515528 | Terminated | Vaccination Plus Ontak in Patients With Metastatic Melanoma | Phase 2 | Interventional | The immune monitoring data failed to demonstrate an improvement in any biologic endpoint with denileukin diftitox. | Actual 17 |
NCT03452267 | Withdrawn | Insulin Signaling in Skeletal Muscle | Phase 2/Phase 3 | Interventional | Lack of funding | Actual 0 |
NCT03758352 | Withdrawn | The Effect of Remote Ischemic Preconditioning on Ischemia/Reperfusion Injury in a Liver Transplant Recipient | N/A | Interventional | Large sample size | Actual 0 |
NCT04000191 | Withdrawn | Ice as an Adjunct for Local Anesthesia During Anorectal Surgeries | N/A | Interventional | Study was neer started and PI left the institution. | Actual 0 |
NCT04015219 | Terminated | Management of Signs and Symptoms Associated With Dry Eye Disease | N/A | Interventional | enrollment constraints | Actual 3 |
NCT04081584 | Suspended | Trans-abdominal Fetal Pulse Oximetry: Tissue Light Scattering | Observational | COVID-19 | Anticipated 30 | |
NCT04081623 | Suspended | Trans-abdominal Fetal Pulse Oximetry: Signal Integrity | Observational | COVID-19 | Anticipated 50 | |
NCT04254172 | Terminated | A Low Interventional Study to Monitor Activity Using Wearable Sensors in Duchenne Muscular Dystrophy | Observational | This low-interventional study (involving no study drug) has been terminated early due to the COVID-19 pandemic, and not for any safety or efficacy reasons. | Actual 2 | |
NCT04342156 | Withdrawn | Safety And Efficacy Of Hydroxychloroquine For At Risk Population (SHARP) Against COVID-19 | Phase 3 | Interventional | The number of patients with COVID-19 in Singapore was coming down for the community and the concerns about the potential side effects particularly when the baseline ECG and serum electrolytes was not proposed. | Actual 0 |
NCT04359277 | Terminated | A Randomized Trial of Anticoagulation Strategies in COVID-19 | Phase 3 | Interventional | the PROTECT study is being transitioned to ACTIV4 ACUTE anticoagulation inpatient study | Actual 77 |
NCT04447729 | Withdrawn | A Study to Test if Fremanezumab Reduces Pain in Patients With Interstitial Cystitis-Bladder Pain Syndrome | Phase 2 | Interventional | Withdrawn due to logistic reasons | Actual 0 |
NCT01673386 | Terminated | A Subject Treatment Preference Study of Tivozanib Versus Sunitinib in Subjects With Metastatic RCC | Phase 2 | Interventional | Sponsor | Actual 58 |
NCT03161470 | Terminated | Efficacy of a Mechanical Chair for Treatment of Benign Paroxysmal Positional Vertigo (BPPV) | N/A | Interventional | Physicians/audiologists preferred to manage patients with BPPV immediately rather than enrolling in study except for difficult to treat cases. | Actual 13 |
NCT03725358 | Withdrawn | A Cluster-RCT to Increase the Uptake of LARCs Among Adolescent Females and Young Women in Cameroon. | N/A | Interventional | Problems with the Performance-Based Financing System in Cameroon, combined with the restrictions on movement brought on by the Covid-19 pandemic. | Actual 0 |
NCT04067362 | Terminated | Chicory Fiber Effect on Satiety and GI Tolerance | N/A | Interventional | COVID-19 | Actual 30 |
NCT04113135 | Withdrawn | The Utilization of Yoga as a Therapeutic Tool to Promote Physical Activity Behavior Change and Improved Postural Control in Individuals With Multiple Sclerosis | N/A | Interventional | Unable to complete initial data collection due to tornado and then COVID-19 has limited in person data collection/intervention. | Actual 0 |
NCT02433067 | Terminated | Physical Activity Intervention on Myocardial Function in Patients With HER2 + Breast Cancer | N/A | Interventional | Actual 89 | |
NCT04583397 | Suspended | Effects of WiFi Exposure on Sleep in Women | N/A | Interventional | Corona | Anticipated 34 |
NCT01811693 | Terminated | Field Administration of Stroke Therapy-Blood Pressure Lowering | Phase 2 | Interventional | The funding period for the study has ended. | Actual 4 |
NCT00001978 | Terminated | Determination of Kidney Function | Observational | All analysis with identifiable specimens/data is complete or site has no identifiers linked to the specimens/data | Actual 456 | |
NCT00896610 | Terminated | Natural History of Autoimmune Diabetes and Its Complications | Observational | All analysis with identifiable specimens/data is complete or site has no identifiers linked to the specimens/data | Actual 356 | |
NCT01907594 | Withdrawn | Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers | Phase 2 | Interventional | Ran out of funding | Actual 0 |
NCT02232477 | Terminated | Extension Study of Intrathecal Enzyme Replacement for Cognitive Decline in MPS I | N/A | Interventional | Termination of study by investigator related to COVID pandemic. | Actual 6 |
NCT02431663 | Terminated | Ketamine in Refractory Convulsive Status Epilepticus | Phase 3 | Interventional | Futility | Actual 57 |
NCT02558205 | Withdrawn | Correlation Between CT Perfusion and Post Y-90 TARE PET/CT Dosimetry | Observational | unable to rectuir | Actual 0 | |
NCT04265690 | Withdrawn | A Multi-Component Nutrition Program for Pregnant and Parenting Teens | N/A | Interventional | The study never launched due to several COVID-19 related barriers. | Actual 0 |
NCT03101592 | Terminated | INTERVAL: Varying Intervals of ART to Improve Outcomes in HIV | N/A | Interventional | Enrollment completed. Outcomes measured after only 1 yr due to loss of funding. | Actual 9118 |
NCT02463669 | Terminated | The Use of Point-of-Care Ultrasound in the Diagnosis of Acute Infectious Mononucleosis in the Emergency Department | Observational | COVID pandemic | Actual 200 | |
NCT02822963 | Withdrawn | Impact of Anticoagulants and Antiplatelets in Patients on Transurethral Resection of the Prostate | Observational | No funding | Actual 0 | |
NCT03107325 | Withdrawn | Biokinetics Study for F-18 FDG in Pediatric Molecular Imaging | Phase 4 | Interventional | No subjects who met the study criteria agreed to participate in two years prior to the COVID-19 crisis. | Actual 0 |
NCT02387164 | Terminated | Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies | Phase 2 | Interventional | The study was interrupted early and terminated when only 26 out of 80 patients were enrolled due to new clinical study results indicating that the current study would not be informative. | Actual 26 |
NCT00017069 | Terminated | Arsenic Trioxide and Dexamethasone in Treating Patients With Recurrent or Refractory Stage II or Stage III Multiple Myeloma | Phase 2 | Interventional | 0 | |
NCT00020969 | Terminated | Arsenic Trioxide in Treating Patients With Myelodysplastic Syndromes | Phase 2 | Interventional | 0 | |
NCT00054184 | Terminated | Polyglutamate Paclitaxel Compared With Docetaxel in Treating Patients With Progressive Non-Small Cell Lung Cancer | Phase 3 | Interventional | Anticipated 350 | |
NCT00054197 | Terminated | Polyglutamate Paclitaxel Compared With Gemcitabine or Vinorelbine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer | Phase 3 | Interventional | 0 | |
NCT00054210 | Terminated | Polyglutamate Paclitaxel Plus Carboplatin Compared With Paclitaxel Plus Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer | Phase 3 | Interventional | 0 | |
NCT00551733 | Terminated | Carboplatin With Either Paclitaxel Poliglumex or Paclitaxel in Treating Women With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer | Phase 3 | Interventional | Anticipated 450 | |
NCT00576225 | Terminated | CT-2103/Carboplatin vs Paclitaxel/Carboplatin for NSCLC in Women With Estradiol > 25 pg/mL | Phase 3 | Interventional | Actual 43 | |
NCT03745352 | Suspended | Pevonedistat With Azacitidine Versus Azacitidine Alone in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia | Phase 2 | Interventional | Other - Pending amendment to change study design | Anticipated 72 |
NCT04575558 | Withdrawn | HOPE: A Trial of Hydroxichloroquine Plus Azithromycin in High Risk COVID-19 | Phase 2 | Interventional | Withdrawn due to lack of study centers interested in participating. | Actual 0 |
NCT00017433 | Terminated | Arsenic Trioxide in Treating Patients With Multiple Myeloma | Phase 2 | Interventional | 0 | |
NCT01849081 | Withdrawn | Evaluating the Efficacy of CPAP Therapy for the Treatment of Fatty Liver | N/A | Interventional | Change in priorities, study closed prior to enrollment | Actual 0 |
NCT04579796 | Suspended | The Accuracy of Ultrasound in the Detection of Placenta Site in the First Trimester. | N/A | Interventional | lack of funding | Anticipated 25 |
NCT03004001 | Terminated | Effect of PCSK9-Antibody (Alirocumab) on Dyslipidemia Secondary to Nephrotic Syndrome | N/A | Interventional | Difficult recruitment | Actual 3 |
NCT03265951 | Terminated | Ramelteon for Complex Insomnia in Veterans With PTSD | Phase 4 | Interventional | Lack of response | Actual 1 |
NCT04057014 | Withdrawn | Immediate Versus Delayed Treatment of Odontogenic Infections | Phase 4 | Interventional | No funding available for the activity | Actual 0 |
NCT01987596 | Terminated | Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer | Phase 3 | Interventional | Actual 23 | |
NCT04293900 | Withdrawn | Diet, Physical Activity and Body Composition Changes During R-CHOP | Observational | Study never started due to COVID pandemic and lack of study funding. | Actual 0 | |
NCT04325893 | Terminated | Hydroxychloroquine Versus Placebo in COVID-19 Patients at Risk for Severe Disease | Phase 3 | Interventional | decrease in number of eligible patients | Actual 259 |
NCT04349449 | Withdrawn | ENTYVIO in Bio-naive Patients With Moderate/Severe Crohn's Disease (CD) in Daily Practice | Observational | Business Decision (no enrollment) | Actual 0 | |
NCT04561817 | Withdrawn | To Evaluate the Safety and Efficacy of Ipatasertib (GDC-0068) in Combination With Paclitaxel in Platinum-resistant Recurrent Epithelial Ovarian Cancer | Phase 2 | Interventional | Evolving data with Ipatasertib that changes the known risk / benefit background in pursuing future studies. | Actual 0 |
NCT01636999 | Withdrawn | Comparing Sedara to Butorphanol in Early Labor | N/A | Interventional | Actual 0 | |
NCT02095210 | Terminated | HER2 PET Imaging in Breast Cancer Patients Using [68GA]ABY-025 | Phase 1 | Interventional | slow recruitment | Actual 2 |
NCT02137265 | Withdrawn | Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism | N/A | Interventional | No funding obtained | Actual 0 |
NCT02557945 | Suspended | Gabapentin in Patients at Clinical Risk for Psychosis | Phase 1/Phase 2 | Interventional | This study is temporarily suspended due to COVID-19 | Anticipated 48 |
NCT02758288 | Withdrawn | BK Virus Post-Kidney Transplant: New Practice Versus Traditional Approach | Observational | Actual 0 | ||
NCT02933073 | Suspended | Study of Oncoimmunome for the Treatment of Stage III/IV Ovarian Carcinoma | Phase 1 | Interventional | Study recruitment is temporary on hold by the sponsor due to patient recruitment challenges and the ongoing review of the investigational adjuvant. | Anticipated 15 |
NCT02975986 | Withdrawn | Renal Uptake of Fatty Acids (FFA) in Patients With Idiopathic Uric Acid Nephrolithiasis (IUAN) | N/A | Interventional | Actual 0 | |
NCT03234465 | Terminated | Efficacy, Safety and Tolerability of AG013 in Oral Mucositis Compared to Placebo When Administered Three Times Per Day | Phase 2 | Interventional | No efficacy could be demonstrated, sponsor decided to prematurely end the study. | Actual 200 |
NCT03286075 | Terminated | Impact of tDCS on Emotional Processing in Healthy Subjects. | N/A | Interventional | The department in charge of this research is no longer able to follow this project. Only two inclusions this study is close | Actual 2 |
NCT03656835 | Suspended | Nanochip Technology in Monitoring Treatment Response and Detecting Relapse in Participants With Diffuse Large B-Cell Lymphoma | N/A | Interventional | Internal review to increase accruals | Anticipated 40 |
NCT03744663 | Suspended | Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films | Phase 2 | Interventional | Study team not ready to start enrolling and unsure of when this may happen. | Anticipated 30 |
NCT03806023 | Terminated | EMG Triggered Closed-Loop Stimulation for Spinal Cord Injury Individuals | N/A | Interventional | Funding expired due to grant for new project (NCT03851302) | Actual 8 |
NCT04113291 | Withdrawn | Randomized Controlled Pilot Trial of DASH Feeding in Older Low Socioeconomic Adults Without Heart Failure | N/A | Interventional | Insufficient funding | Actual 0 |
NCT04206865 | Withdrawn | Comparison of ARNI to Alternate Oral Vasodilator Therapies in Patients With Low Cardiac Output | Phase 4 | Interventional | New study initiated | Actual 0 |
NCT04401631 | Withdrawn | Analytical Validation of the abioSCOPE Device With an IgE Test Panel: Point-of-Care Precision, Sample Type Comparison and Method Correlation | Observational | Sponsor financial has been stopped | Actual 0 | |
NCT04442932 | Withdrawn | abioSCOPE IgE Assay to Aid in the Diagnosis of Allergies | Observational | Sponsor financial has been stopped. | Actual 0 | |
NCT03219866 | Terminated | Nebulizer Versus Dry Powdered Inhalers for COPD | Phase 4 | Interventional | Lower enrollment than Sponsor expected - Sponsor stopped study | Actual 40 |
NCT03285308 | Terminated | A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01 | Phase 3 | Interventional | The Relamorelin program is being terminated solely based on a business decision. | Actual 336 |
NCT03369184 | Terminated | Elective Percutaneous Coronary Intervention With or Without Supplemental OXYgen | Phase 3 | Interventional | Slow recruitment | Actual 65 |
NCT03421678 | Withdrawn | Ethnic/Racial Differences in Metabolism and DNA Adduct Formation | Observational | Study was completed at other sites | Actual 0 | |
NCT03426345 | Terminated | Study to Evaluate the Safety and Efficacy of Relamorelin in Patients With Diabetic Gastroparesis Study 02 | Phase 3 | Interventional | The Relamorelin program is being terminated solely based on a business decision | Actual 311 |
NCT03741803 | Suspended | Relationship Between Delayed Cord Clamping at Birth and Neonatal Bilirubin Levels in Parturients With a Prior Child Requiring Therapy for Neonatal Jaundice | N/A | Interventional | Study paused due to COVID-19 | Anticipated 100 |
NCT03801889 | Withdrawn | SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias | Phase 2 | Interventional | Protocol suspended prior to patient enrollment | Actual 0 |
NCT03984604 | Terminated | Investigation of the Efficacy and Safety of CHI-921 in Insomnia. | Phase 2 | Interventional | COVID-19 | Actual 21 |
NCT04048746 | Terminated | Evaluation of the Written Information Delivered by the General Practitioner of the Patients Presenting to the Emergency Room for an Aggravation of Asthma | Observational | The PI decided to stop. | Actual 10 | |
NCT04171648 | Terminated | Effect of Dry Roasted Peanuts and Boiled Peanuts on Glycemic Control | N/A | Interventional | Covid-19 Pandemic halted my study due to exposure risks. | Actual 24 |
NCT04201743 | Withdrawn | An Amniotic Membrane Injection Comparing Two Doses (1 mL and 2mL Injection) in the Treatment of Osteoarthritis of the Knee | Phase 4 | Interventional | Resources limited secondary to COVID-19 pandemic. | Actual 0 |
NCT04379375 | Terminated | Nudges to Improve Health Behaviors That Limit COVID-19 Spread | N/A | Interventional | Slow enrollment rate | Actual 45 |
NCT02715765 | Terminated | The Use of Transcranial Electrical Stimulation for Hallucinations | N/A | Interventional | PI left university, the grant could not be transferred, no data was collected | Actual 3 |
NCT02416193 | Terminated | Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes? (THINK-D) | Phase 2 | Interventional | the study was halted prematurely due to slow recruitment and expiration of funding | Actual 56 |
NCT01052896 | Withdrawn | Gabapentin in Functional Dyspepsia Refractory to Proton Pump Inhibition | Phase 3 | Interventional | Unable to recruit subjects - unworkable | Actual 0 |
NCT00969956 | Suspended | Time To Complications Occurs in Diabetes | Observational | Local regulations | Anticipated 950 | |
NCT00991315 | Terminated | Collecting and Storing Blood and Tumor Tissue Samples From Patients Undergoing Prostatectomy or Transurethral Resection of the Prostate | Observational | Specimens are now collected through the BRS protocol. | Actual 126 | |
NCT03189030 | Terminated | Study of Personalized Immunotherapy in Adults With Metastatic Colorectal Cancer | Phase 1 | Interventional | Study terminated due to business realignment | Actual 28 |
NCT03333694 | Terminated | Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis) | Phase 1 | Interventional | The study fully enrolled and completed after last patient completed the study | Actual 40 |
NCT03428763 | Withdrawn | ELECTOR Treat-to-target Via Home-based Disease Activity Monitoring of Patients With Rheumatoid Arthritis | N/A | Interventional | Technical problems with POC | Actual 0 |
NCT04230291 | Terminated | Hidradenitis Suppurativa Written Action Plan | N/A | Interventional | Principal investigator is not longer at this institution | Actual 8 |
NCT02240706 | Terminated | Phase I/II Trial to Investigate BI 836858 in Myelodysplastic Syndromes | Phase 2 | Interventional | Actual 25 | |
NCT02505087 | Terminated | Pharmacological Treatment of a Rare Genetic Disease: N-acetylcysteine in Myopathy Associated Selenoprotein N-related Myopathy (SEPN1-RM) | Phase 2/Phase 3 | Interventional | Actual 7 | |
NCT04574427 | Suspended | INtra-operative Evaluation of a Novel FLUorescENt C-mEt Tracer in Penile and Tongue | Observational | Tracer not available. | Anticipated 20 | |
NCT01803334 | Terminated | Impact of Marking Surgical Incision on Patient's Abdomen | N/A | Interventional | Not enough participants could be enrolled and so the PI decided to close the study. No participants completed the study | Actual 4 |
NCT02476955 | Terminated | Open-label Phase 1b Study of ARQ 092 in Combination With Anastrozole | Phase 1 | Interventional | Actual 41 | |
NCT02808806 | Terminated | A Reduction in Time With Electronic Monitoring In Stroke | N/A | Interventional | technical difficulties | Actual 80 |
NCT03277612 | Terminated | Effects of C-section Delivery on Infant Brain Development | Observational | Study halted prematurely and will not resume; participants are no longer being examined | Actual 9 | |
NCT03699904 | Terminated | Epstein-Barr Virus Suppression in Chronic Obstructive Pulmonary Disease (EViSCO): a Phase 2 Randomised Control Trial | Phase 2 | Interventional | In light of the evolving Covid19 pandemic ongoing study recruitment was felt to pose an unacceptable risk to patient safety. | Actual 85 |
NCT03838835 | Terminated | Equine Facilitated CBT Group Therapy for Youth Anxiety | N/A | Interventional | COVID-19 | Actual 59 |
NCT03981250 | Suspended | Effect of One Minute of Resistance Exercise Per Day on Muscular Strength (The ONE Study) | N/A | Interventional | Covid-19 | Anticipated 56 |
NCT04085393 | Withdrawn | Granisetron Extended Release Injection (GERSC) for the Prevention of Chemotherapy-induced Nausea and Vomiting | Phase 2 | Interventional | sponsor withdrew study | Actual 0 |
NCT04118374 | Suspended | A Pilot Study to Determine Iatrogenic Hyperinsulinemia's Contribution to Insulin Resistance and Endothelial Dysfunction in Type 1 Diabetes | N/A | Interventional | research-related activities have been impacted by the COVID-19 outbreak (participant recruitment/enrollment/on-site subject visits) | Anticipated 10 |
NCT04379492 | Withdrawn | A Study of Hydroxycholoroquine Compared to Placebo as Treatment for People With COVID-19 | Phase 2 | Interventional | Emerging evidence does not support the use of HCQ for treatment or prevention of SARS -CoV2 infection. No pts have been enrolled. | Actual 0 |
NCT00843531 | Terminated | RAD001 and Erlotinib in Patients With Neuroendocrine Tumors | Phase 2 | Interventional | Low Accrual | Actual 17 |
NCT04019067 | Withdrawn | Magnetically Controlled Capsule Endoscopy First vs. Standard Algorithm in Patients With Melena | N/A | Interventional | few patients met all the inclusion criteria | Actual 0 |
NCT00213720 | Terminated | Treatment of Subclinical Hyperthyroidism | Observational | recruitment difficulties | Actual 145 | |
NCT01675154 | Terminated | Phase 2 Study of Orlistat and SLx-4090 for the Treatment of Type 1 Hyperlipoproteinemia | Phase 2 | Interventional | Due to unavailability of the drug. | Actual 5 |
NCT02283905 | Terminated | Amphotericin-B and Voriconazole for Pulmonary Blastomycosis | Phase 4 | Interventional | Poor enrollment numbers of patients | Actual 2 |
NCT02764164 | Terminated | Transcranial Direct Current Stimulation (TDCS) for Auditory Hallucinations in Early Onset Schizophrenia (EOS) | N/A | Interventional | Lack of funding | Actual 1 |
NCT03843476 | Withdrawn | Personalized Spine Study Group Registry | Observational [Patient Registry] | Requested by surgeons to pursue new study | Actual 0 | |
NCT03953625 | Suspended | Interest of the Return to Primary Care of the "Low Back Pain Booklet" of Health Insurance in the Recovery of Common Acute Low Back Pain | N/A | Interventional | The PI decided. | Anticipated 100 |
NCT04130282 | Terminated | VAC077: Safety and Immunogenicity of the Pfs25-IMX313/Matrix-M Vaccine | Phase 1 | Interventional | Delays caused by Covid-19 | Actual 1 |
NCT04348890 | Withdrawn | Proof of Concept Trial of Vamorolone in Pediatric Ulcerative Colitis | Phase 1/Phase 2 | Interventional | Programmatic decision | Actual 0 |
NCT04365582 | Suspended | OUTpatient Treatment of COVID-19 in Patients With Risk Factor for Poor Outcome | Phase 3 | Interventional | The PI decided. | Anticipated 640 |
NCT04480879 | Suspended | Evaluation of AZD8154 Concentrations in Blood | Phase 1 | Interventional | Need for evaluation of emerging pre-clinical toxicology findings | Anticipated 15 |
NCT04571814 | Suspended | Targeting the ERN Computerized Intervention Targeting the Error-related Negativity in Young Children | N/A | Interventional | COVID-19 | Anticipated 175 |
NCT01831596 | Terminated | Evaluation of a Novel Post-Surgical Dressing | N/A | Interventional | The study was terminated by Spiracur. Efforts were made to contact the PI/study team members, but were unsuccessful. | Actual 59 |
NCT03839277 | Suspended | Adenoma Detection Rate Using Endocuff Vision in China | N/A | Interventional | One investigator is out-of-service due to carrying out another task. | Anticipated 1200 |
NCT03888534 | Withdrawn | Intravenous Ixazomib in Pediatric Participants With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LLy) | Phase 1 | Interventional | Business decision (no safety or efficacy concerns) | Actual 0 |
NCT04042623 | Terminated | Study of Safety and Efficacy of AVB-S6-500 in Patients With IgA Nephropathy | Phase 2 | Interventional | Business reasons | Actual 1 |
NCT04233359 | Terminated | A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer. | N/A | Interventional | To few patients recruited to allow for study completion within ph.d. project. | Actual 4 |
NCT04275128 | Terminated | Cooled Versus Conventional Genicular Radiofrequency Ablation for Chronic Knee Pain | Observational | Insurance companies no longer cover this procedure | Actual 1 | |
NCT04358081 | Terminated | Hydroxychloroquine Monotherapy and in Combination With Azithromycin in Patients With Moderate and Severe COVID-19 Disease | Phase 3 | Interventional | low enrollment | Actual 20 |
NCT04537143 | Withdrawn | Image Biomarkers for Progression of AMD | Observational | Funding for staff no longer available | Actual 0 | |
NCT04569214 | Withdrawn | The Efficacy and Safety of PAZ320 on PPG and Insulin Blood Levels in Type II Diabetic Patients | Phase 2 | Interventional | Actual 0 | |
NCT03925428 | Withdrawn | Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas | Phase 1 | Interventional | Other - Protocol moved to Disapproved | Actual 0 |
NCT04116359 | Withdrawn | Testing of the Addition of a New Anti-cancer Drug, Molibresib, to Chemotherapy Treatment (Etoposide and Cisplatin) for Patients With NUT Carcinoma | Phase 1/Phase 2 | Interventional | Other - Protocol moved to Disapproved | Actual 0 |
NCT01930175 | Terminated | Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris | Phase 2 | Interventional | The study recruitment was terminated in Dec-2015 for strategic reasons related to the development of the compound. | Actual 13 |
NCT02300961 | Suspended | Feasibility Neurocognitive Outcome After Transplant | N/A | Interventional | Covid-19 | Anticipated 35 |
NCT02563015 | Terminated | Can Correction of Low Vitamin D Status in Infancy Program for a Leaner Body Composition? | N/A | Interventional | Covid19 pandemic prevented continuation of study visits | Actual 132 |
NCT02858466 | Terminated | Structural and Functional Brain Reorganization in Neuropathic Pain: Basal State of Local Cerebral Blood Flow and Functional Connectivity | N/A | Interventional | failure to recruit | Actual 68 |
NCT02858479 | Terminated | Structural and Functional Brain Reorganization in Neuropathic Pain. Influences of the Loss of Sensitivity and the Atrophy Cortical on Activations Due to Stimulation Allodynic | N/A | Interventional | failure to recruit | Actual 41 |
NCT03151772 | Terminated | Bioavailability of Disulfiram and Metformin in Glioblastomas | Early Phase 1 | Interventional | Problems with including patients | Actual 3 |
NCT03435042 | Suspended | A Hypnosis-based Group Intervention to Improve Quality of Life in Children With Cancer and Their Parents. | N/A | Interventional | Recruitment and organisational difficulties | Anticipated 30 |
NCT00536939 | Terminated | Trial of Paclitaxel, Bevacizumab, and Enzastaurin Versus Paclitaxel, Bevacizumab and Placebo for Breast Cancer | Phase 2 | Interventional | Study has been terminated due to slow enrollment | Actual 2 |
NCT04563728 | Suspended | Use Surveillance Technology to Reduce Elder Abuse Recidivism | N/A | Interventional | Covid-19 | Anticipated 10 |
NCT03292835 | Suspended | Complex Cutaneous Leishmaniasis Healing Study in Algeria | Observational [Patient Registry] | Political Issues in Algeria and now Covod-19 lock-down | Anticipated 100 | |
NCT03391856 | Terminated | Prolonged Isolated Thrombocytopenia After Allo-SCT : N-acetyl-L-cysteine (NAC) Versus Supportive Therapy | Phase 2/Phase 3 | Interventional | protocol changed | Actual 15 |
NCT03698747 | Terminated | Myelin Imaging in Concussed High School Football Players | Observational | PI left organization | Actual 13 | |
NCT04153071 | Withdrawn | Unipolar Microplasma Radiofrequency Device: In-vivo Histologic Study | N/A | Interventional | Per Investigator and sponsor decision | Actual 0 |
NCT04236037 | Terminated | Ultrasound-guided Biopsy of the Pleura as a Supplement to Extraction of Fluid in Patients With One-sided Fluid in the Pleura | N/A | Interventional | It is unrealistic to succeed with sufficient inclusion within the timeframe of the study, why it is terminated. | Actual 5 |
NCT02331095 | Terminated | Statin Use in Patients With Acute VTE | Early Phase 1 | Interventional | Low recruitment | Actual 21 |
NCT04343690 | Withdrawn | COPING With COVID-19( CWC-19) | N/A | Interventional | Study Ended May 1, 2020 with no enrollment | Actual 0 |
NCT03409341 | Withdrawn | Personalizing Immune Checkpoint Inhibitor Therapy | Observational | No enrollment | Actual 0 | |
NCT03673566 | Withdrawn | Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - CHMCO | N/A | Interventional | Business pivot caused termination of study before enrollment. | Actual 0 |
NCT03673579 | Withdrawn | Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - MHSB | N/A | Interventional | Business pivot caused termination of study before enrollment. | Actual 0 |
NCT03791541 | Withdrawn | A Study Evaluating the Use of Potential Predictors of Readmission in Hospitalized Medicine Patients | N/A | Interventional | Pilot study results not meaningful. Students researchers graduated. | Actual 0 |
NCT04039568 | Suspended | Meditation Versus Education for Improving Depression in Chronic Pain, a Randomized Controlled Trial | N/A | Interventional | COVID-19 Pandemic. Update in-process. | Anticipated 160 |
NCT04202471 | Withdrawn | Chlorhexidine Cloths to Reduce Surgical Site Infection in Cesarean Deliveries | N/A | Interventional | COVID-19 pandemic | Actual 0 |
NCT03486002 | Terminated | EFFEXTS OF THE CLEANSWEEP SUCTION CATHETER | N/A | Interventional | Access to the devices was halted by the sponsor | Actual 8 |
NCT03626623 | Terminated | Diabetic Foot Ulcer Study Comparing Cytal Wound Matrix 1-Layer to Standard of Care | N/A | Interventional | Sponsor Discretion | Actual 15 |
NCT03712930 | Terminated | Treatment of Metastatic Castration-Resistant Prostate Cancer With Homologous Recombination Deficiency | Phase 2 | Interventional | Sponsor's decision to revisit the development approach for prostate cancer. | Actual 13 |
NCT03793712 | Terminated | Study With Lu AF11167 for the Treatment of Negative Symptoms in Patients With Schizophrenia | Phase 2 | Interventional | Lack of efficacy based on interim analysis | Actual 168 |
NCT03929497 | Terminated | Flexible-dose Long-term Extension Study of Lu AF11167 in Patients With Schizophrenia With Prominent Negative Symptoms | Phase 2 | Interventional | Lack of efficacy based on the interim analysis in the 17972A study | Actual 96 |
NCT03932656 | Suspended | Latent Toxoplasmosis in Females With Borderline Personality Disorder | Observational | Funding issues | Anticipated 100 | |
NCT04018508 | Suspended | Massage Therapy for Self-efficacy in LVAD Recipients | N/A | Interventional | COVID19 pandemic closed in-person clinics temporarily | Anticipated 74 |
NCT04293978 | Suspended | Virtual Reality Relaxation for Addiction Inpatients | N/A | Interventional | Recruitment and intervention provision paused due to COVID-19 situation. Planned to resume. | Anticipated 40 |
NCT02285179 | Suspended | Clinical Trial to Evaluate the Safety and Effectiveness of GDC-0032 When Given Alongside Tamoxifen | Phase 1/Phase 2 | Interventional | Inclusion stopped due to COVID-19 | Anticipated 290 |
NCT03689985 | Terminated | Functionality and Accuracy of the smART System in Real-Life ICU Settings | N/A | Interventional | Due to the company's intent to conduct a new study under a different protocol with the smART+ System which is a more advanced version of the smART System | Actual 2 |
NCT04044950 | Withdrawn | A Phase II Study of Neoadjuvant E7 TCR T Cell Immunotherapy for Borderline Resectable and Unresectable Stage I HPV-Associated Oropharyngeal Cancer | Phase 2 | Interventional | The study was closed due to investigator discretion based on the lack of ability to recruit patients and research goals of the program. | Actual 0 |
NCT04428918 | Withdrawn | Biospecimen Procurement for Immunological Landscape Studies Following Hematopoietic Cell Transplantation | Observational | The study was closed due to investigator discretion based on the lack of ability to recruit patients and research goals of the program. | Actual 0 | |
NCT01663766 | Terminated | Phase I Study of Milatuzumab for Graft Versus Host Disease | Phase 1 | Interventional | PIs agreed no safety signals were shown, drug did not appear to lessen the risk of preventing GVHD no further patients would be enrolled | Actual 12 |
NCT02161679 | Withdrawn | Phase II Study of IMMU-132 Alone or in Combination With Carboplatin in Patients With Triple-Negative Breast Cancer | Phase 2 | Interventional | FDA asked to administratively split from IND115621- to open a new IND you need to file a protocol we only drafted it to get the IND open - never initiated | Actual 0 |
NCT02548494 | Terminated | Early Administration of Long-acting Insulin Treatment of Diabetic Ketoacidosis in Pediatric Type 1 Diabetes | N/A | Interventional | Project terminated due to insufficient resources for recruitment. | Actual 17 |
NCT02826655 | Terminated | Adaptive Optics for Ophthalmic Technologies | N/A | Interventional | lack of funding | Actual 4 |
NCT02267772 | Terminated | IV Acetaminophen vs IV Morphine for Pain Control in Pregnant Women | N/A | Interventional | Difficulties in recruitment | Actual 163 |
NCT03121079 | Withdrawn | Interferon-α Prevents Leukemia Relapse of AML Patients After Transplantation | N/A | Interventional | there was almost no patient would enroll in this study. | Actual 0 |
NCT03304184 | Suspended | The Role of Biodentine in Class V Dental Lesions on Oral Health Related Quality of Life | Phase 3 | Interventional | COVID | Anticipated 40 |
NCT03379558 | Terminated | Praluent® (Alirocumab) Pregnancy Exposure Registry: An OTIS Pregnancy Surveillance Study | Observational | (due to change in the post-marketing requirement to assess alirocumab during pregnancy) | Actual 37 | |
NCT03362021 | Terminated | Comparison of Two Different Sedation Protocols During Transvaginal Oocyte Retrieval | Observational | Primary investigator transferred in another hospital; ongoing pandemic; | Actual 80 | |
NCT03171051 | Terminated | LED Device for Non-Invasive Lipolysis | N/A | Interventional | device development placed on hold | Actual 10 |
NCT03615508 | Terminated | Exploration of Pupil Dilation in Horner's Patients Taking Flomax | Phase 4 | Interventional | incomplete enrollment | Actual 1 |
NCT03726996 | Terminated | Desipramine in Infantile Neuroaxonal Dystrophy (INAD). | Phase 4 | Interventional | Funding exhausted | Actual 4 |
NCT03742973 | Terminated | A Study of Baricitinib (LY3009104) in Participants With Primary Biliary Cholangitis Who do Not Respond or Cannot Take UDCA | Phase 2 | Interventional | Study was terminated due to enrollment futility. | Actual 2 |
NCT03867708 | Withdrawn | Outcomes of Transcatheter ASD Closure Guided by 3D-TEE | Observational | No participants found | Actual 0 | |
NCT03960242 | Suspended | Evaluation of Clinical Progression in Patients With Motor Predominant Parkinson Disease. | Observational | Temporary halt of the trial due to COVID-19 crisis related delays | Anticipated 30 | |
NCT01007136 | Terminated | Transcranial Direct Current Stimulation (tDCS)-Enhanced Stroke Recovery | N/A | Interventional | Funding limit reached due to slower then anticipated recruitment. | Actual 62 |
NCT02301000 | Terminated | IMT for Primary Clostridium Difficile Infection | Phase 2/Phase 3 | Interventional | Slow recruitment in pilot phase. A follow-up trial is launched (NCT03796650). | Actual 21 |
NCT03021252 | Terminated | Respiratory Muscle Training in Stroke Swallowing Disorders | N/A | Interventional | Because of the SARS-COV2 pandemic. Recruitment stopped at 48 patients | Actual 50 |
NCT01239160 | Terminated | Two Pneumatic Compression Devices in the Treatment of Lower Extremity Lymphedema | N/A | Interventional | Futility and underpowering of endpoint data | Actual 238 |
NCT03059407 | Suspended | Impact of Therapy Dog Presence on Pediatric Echocardiogram | N/A | Interventional | Due to COVID-19, the study has been put on hold. | Anticipated 160 |
NCT03332355 | Suspended | Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 2 | Phase 1 | Interventional | Business Reasons | Anticipated 9 |
NCT03721796 | Terminated | Cancer Treatment Decision-making in the HIV Population: an Observational Study of Physician-patient Interactions | Observational | study design changed due to COVID-19 | Actual 14 | |
NCT03896334 | Suspended | Effect of Isometric Handgrip Training on Ambulatory Blood Pressure in Patients With Hypertension | N/A | Interventional | The study is suspended because of the COVID-19 pandemic | Anticipated 250 |
NCT04421664 | Terminated | Preemptive Therapy for SARS-Coronavirus-2 (COVID-19 PEP Canada) | Phase 3 | Interventional | Request of Health Canada after publication of https://doi.org/10.7326/M20-4207 | Actual 70 |
NCT03447730 | Terminated | Safety, Tolerability and Pharmacodynamics of SYNB1020 | Phase 1/Phase 2 | Interventional | Interim futility analyses identified a lack of SYNB1020 efficacy. | Actual 23 |
NCT00894751 | Terminated | Two Anesthetic Techniques in Magnetic Resonance Imaging (MRI) | Phase 1 | Interventional | low enrollment and high participant withdraw | Actual 98 |
NCT01658852 | Withdrawn | Effects and Safety of Metronidazole in Patients With Gastrectomy | Phase 3 | Interventional | Because of difficulties on recruiting participants | Actual 0 |
NCT02920190 | Withdrawn | Antigen-Lipid-Driven Monoclonal Gammopathies Targeting Epicardial Fat | Phase 4 | Interventional | Lack of funds to cover the costs of the study medications | Actual 0 |
NCT04145193 | Withdrawn | Novel Oncology Therapies in Combination With Adjuvant Chemo in High-risk MSS-CRC | Phase 2 | Interventional | Study withdrawn prior to enrollment due to changing standard of care landscape. | Actual 0 |
NCT02488278 | Withdrawn | GLUCOME USABILITY STUDY | N/A | Interventional | Actual 0 | |
NCT03384238 | Suspended | Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery | Phase 1/Phase 2 | Interventional | Interim Analysis | Anticipated 27 |
NCT03517696 | Withdrawn | Membrane Sweeping in Early Labor and Delivery Outcomes | N/A | Interventional | Study IRB approval expired | Actual 0 |
NCT03551535 | Withdrawn | Monitored Home Exercise in Pregnancy | N/A | Interventional | Study IRB approval expired | Actual 0 |
NCT03704285 | Suspended | Development of pk/pd Model of Propofol in Patients With Severe Burns | Observational | Outbreak COVID 19 | Anticipated 30 | |
NCT03705338 | Suspended | Predictive Model in EEG for Induction and Emergence in Pediatric With Propofol | Observational | Outbreak COVID 19 | Anticipated 20 | |
NCT03855683 | Suspended | Stress, Anxiety, and Mood Group Therapy | N/A | Interventional | Social distancing regulations related to COVID19. | Anticipated 50 |
NCT04220476 | Withdrawn | CIMER: Combined Immunotherapies in Metastatic ER+ Breast Cancer | Phase 2 | Interventional | Initiating a new study with revised Statistics. | Actual 0 |
NCT02844855 | Terminated | Memory for Action in Neurological Patients | N/A | Interventional | failure to recruit 83/99 | Actual 83 |
NCT03224975 | Terminated | Acute Pain Memory Among Former Burned: Exploration of fMRI. | N/A | Interventional | failure to recruit | Actual 24 |
NCT03604991 | Suspended | Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery | Phase 2/Phase 3 | Interventional | Scheduled Interim Monitoring | Anticipated 278 |
NCT00226746 | Withdrawn | Efficacy Study of Gemcitabine, Paclitaxel, and Irradiation in the Treatment of Pancreatic Cancer | Phase 2 | Interventional | Actual 0 | |
NCT04558892 | Terminated | Anti-Xa Activity of Enoxaparin for Prevention of Venous Thromboembolism in Severe Nephrotic Syndrome. | Phase 2/Phase 3 | Interventional | The primary objectives were achieved. | Actual 65 |
NCT02033278 | Terminated | Infusion Intracoronary of Mononuclear Autologous Adult no Expanded Stem Cells of Bone Marrow on Functional Recovery in Patients With Idiopathic Dilated Cardiomyopathy and Heart Failure. | Phase 2 | Interventional | Low recruitment rate, bibliographic evidence of lack of efficacy | Actual 27 |
NCT02395237 | Withdrawn | COMPOUND (INN): HOE490O - GLIMEPIRIDE / METFORMIN HCl (Amaryl® M)0 (Glimepiride/Metformin Hydrochloride Immediate Release Combination Tablet) in Fed Conditions in Healthy Male and/or Female Subjects. | Phase 1 | Interventional | Actual 0 | |
NCT02972281 | Terminated | Systematic Search for Primary Immunodeficiency in Adults With Infections | N/A | Interventional | deficient inclusions | Actual 120 |
NCT03311568 | Terminated | Microcirculatory Alterations in Critical Disease: New Ultrasound Technology | N/A | Interventional | Researcher has quit. Question still unanswered. A related study (observational, not to be registered) has started recently. | Actual 30 |
NCT03559517 | Terminated | Efficacy and Safety Study of Ontamalimab as Induction Therapy in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 305) | Phase 3 | Interventional | Sponsor decision to discontinue the SHP647 (ontamalimab) clinical trial development program for inflammatory bowel diseases (IBD) early. | Actual 30 |
NCT03860753 | Terminated | Effects of Pioglitazone on Stress Reactivity and Alcohol Craving (Pilot) | Phase 1/Phase 2 | Interventional | Halted enrollment due to COVID-19 | Actual 4 |
NCT04532554 | Withdrawn | Growth Hormone in Obese Cases With Covid-19 | Phase 4 | Interventional | No participants enrolled | Actual 0 |
NCT02153684 | Suspended | Canadian Cohort on the Origin and Progression of Airway Disease: Physiology Platform | Observational | Temporarily suspended due to COVID-19 | Anticipated 120 | |
NCT02925364 | Terminated | Functional and Anatomical MRI of the Spinal Cord and Peri-spinal Tissues | Observational | Slow recruitment | Actual 30 | |
NCT02952573 | Terminated | Testing JNJ-42756493 In Combination With Dexamethasone in Multiple Myeloma That Came Back After a Period of Improvement | Phase 2 | Interventional | Low patient accrual | Actual 20 |
NCT03017287 | Terminated | Safety and Efficacy of the GlucoMe APP in Patients With Uncontrolled Diabetes Treated With MDI | N/A | Interventional | Actual 40 | |
NCT03018756 | Suspended | Nebulized Fentanyl in Patients With Mild to Moderate Interstitial Lung Disease and Chronic Dyspnea | Phase 3 | Interventional | Temporarily suspended due to COVID-19 | Actual 21 |
NCT03357692 | Withdrawn | All-on-Four Implants With Ultrasonic | N/A | Interventional | no enough patients have been enrolled | Actual 0 |
NCT03405090 | Suspended | Differential Mechanisms of Dyspnea Relief in Advanced COPD: Opiates vs. Bronchodilators | Phase 4 | Interventional | Temporarily suspended due to COVID-19 | Anticipated 17 |
NCT03767829 | Terminated | A Study of ALN-AAT02 in Healthy Participants and Participants With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease | Phase 1/Phase 2 | Interventional | The sponsor decided not to proceed with Part B for business reasons. | Actual 32 |
NCT03769961 | Terminated | Ataxia in Essential Tremor: Describing the Differences Between Disease Process and Treatment Effect | Observational | Low enrollment | Actual 6 | |
NCT03786367 | Suspended | Dyspnea in Chronic Thromboembolic Pulmonary Hypertension | Observational | Temporarily suspended due to COVID-19 | Anticipated 20 | |
NCT03790774 | Terminated | Neurofeedback in Alzheimer's Disease | N/A | Interventional | Due to COVID-19 concerns and restrictions in our at-risk population, interactions were halted. | Actual 5 |
NCT03824535 | Suspended | 18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules | Phase 2 | Interventional | Suspended Due to Covid-19 | Anticipated 50 |
NCT03957096 | Terminated | A Safety Study of SGN-CD47M in Patients With Solid Tumors | Phase 1 | Interventional | Sponsor decision based on portfolio prioritization | Actual 16 |
NCT04077385 | Withdrawn | Memory-Updating Technique to Reduce Food Craving and High Calorie Food Intake Among Individuals With Overweight/Obesity | N/A | Interventional | PI resigned from faculty position and K23 award was terminated early | Actual 0 |
NCT04098016 | Suspended | Healthy Roots Digital Intervention | N/A | Interventional | Aim 1 enrollment and study activities have been completed. Aim 2 start date is now anticipated for 01/11/2021. | Anticipated 50 |
NCT04239222 | Suspended | Feasibility Study to Evaluate a New Energy Storage and Return Prosthetic Foot | N/A | Interventional | Study suspended due to COVID 19 | Anticipated 24 |
NCT04558580 | Withdrawn | Safety Study of Rufinamide Given as an add-on Therapy to Treat Patients With Seizures | Phase 3 | Interventional | Actual 0 | |
NCT02817113 | Terminated | Study of NC-6004 in Combination With 5-FU and Cetuximab in Patients With Head and Neck Cancer | Phase 1 | Interventional | Strategy change | Actual 4 |
NCT02923232 | Terminated | Ocular Adaptation and Visual Performance for Accommodative Contact Lens | N/A | Interventional | Funding organization requested to stop the study | Actual 32 |
NCT03567356 | Suspended | Treatment of Opioid Use: Medication Adherence Therapy | N/A | Interventional | IRB temporarily suspended study due to COVID-19 | Anticipated 50 |
NCT03858621 | Suspended | Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fentanyl | N/A | Interventional | COVID 19 outbreak | Anticipated 100 |
NCT04008602 | Suspended | Effectiveness of Quick Icing (QI) Technique on Strenght of Jump. | N/A | Interventional | COVID-19 | Anticipated 150 |
NCT04243031 | Withdrawn | QuantiFERON Access Clinical Performance Study Protocol | Observational | Business Decision | Actual 0 | |
NCT04306783 | Withdrawn | In-Home Sensor Monitoring of Older Adults With Cancer | N/A | Interventional | Investigator is leaving the university | Actual 0 |
NCT04360512 | Terminated | Dose-response of Talus Mobilizations | N/A | Interventional | Suspended due to the covid-19 pandemic. | Actual 42 |
NCT02787902 | Suspended | Weight Management in Mothers and Adult Daughters | N/A | Interventional | Trial suspended due to COVID-19. | Anticipated 168 |
NCT03212963 | Terminated | Evaluation of Adrenal Suppression Potential and Pharmacokinetics of Halobetasol Lotion 0.05% | Phase 4 | Interventional | Sponsor's Decision | Actual 16 |
NCT03045705 | Withdrawn | Evaluation of the Effect the Medical Team in the Delivery Room Has on Pain Management During Labor. | N/A | Interventional | Problem with patient recruitment | Actual 0 |
NCT03046654 | Terminated | Cervical Cerclage Position Throughout the Pregnancy. | N/A | Interventional | Difficulty in patient recruitment | Actual 7 |
NCT03930290 | Terminated | Physiologic Elasticity Changes During Pregnancy and After Labor. | Observational | Difficulty in patient recruiting | Actual 12 | |
NCT00751101 | Terminated | Nicotine Patches in Reducing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine For Metastatic Breast Cancer | Phase 2 | Interventional | Low Accrual | Actual 24 |
NCT02522273 | Withdrawn | Evaluation of the 'SensPoint' Lactate Meter in the Estimation of Foetal Scalp Blood and Umbilical Cord Blood Lactate | Observational | Actual 0 | ||
NCT04274452 | Withdrawn | A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP) | Phase 3 | Interventional | The ARGX-113-1908 study will be replaced by a similar design with a subcutaneous formulation (ARGX-113-2004) | Actual 0 |
NCT04548622 | Terminated | Bilateral Repetitive Transcranial Magnetic Stimulation for Auditory Hallucinations Results | N/A | Interventional | Dr. Ralph Hoffman unexpectedly passed away. | Actual 15 |
NCT02648932 | Terminated | The Rapid Study: Randomized Phase II Study To Expedite Allogeneic Transplant With Immediate Haploidentical Plus Unrelated Cord Donor Search Versus Matched Unrelated Donor Search For AML And High-Risk MDS Patients | Phase 2 | Interventional | Poor accrual | Actual 9 |
NCT02822196 | Withdrawn | Serratus Anterior Muscle Plane Block vsThoracic Paravertebral Block For Unilateral Mastectomies | Phase 4 | Interventional | Critical study personnel left the institution | Actual 0 |
NCT02936206 | Terminated | Examination of Breast Cancer Cells of Pre-menopausal and Post-menopausal Women Before and After Exposure to Tamoxifen or Fulvestrant. | Phase 1 | Interventional | low accrual rate | Actual 4 |
NCT03348826 | Withdrawn | Study of Sodium Bicarbonate in Restoring Blocked Catheters | Phase 2 | Interventional | No participants were enrolled | Actual 0 |
NCT03566823 | Terminated | Efficacy and Safety Study of Ontamalimab as Induction Therapy in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 306) | Phase 3 | Interventional | Sponsor decision to discontinue the SHP647 (ontamalimab) clinical trial development program for inflammatory bowel diseases (IBD) early. | Actual 34 |
NCT04098887 | Withdrawn | Lattice Stereotactic Body Radiation Therapy (Lattice SBRT) for Localized Unresectable or Metastatic Conventional Type Chondrosarcoma | N/A | Interventional | Investigator decided to not go forward with the study. | Actual 0 |
NCT04256655 | Withdrawn | Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of CDX 6114 in PKU Patients | Phase 1 | Interventional | study product composition to move from liquid to solid | Actual 0 |
NCT04401527 | Withdrawn | Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite | Phase 2 | Interventional | No recruitment | Actual 0 |
NCT03760250 | Suspended | Imiquimod for Preventing Keloid Recurrence | Phase 2 | Interventional | Investigator decision | Actual 5 |
NCT01495247 | Terminated | Phase Ib/II Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer | Phase 1/Phase 2 | Interventional | Study did not meet Phase Ib primary objective to establish the maximum tolerated dose/recommended dose for Phase II | Actual 18 |
NCT02027012 | Terminated | Treatment of Resistant Hypertension by Renal Denervation in China | N/A | Interventional | company strategic change | Actual 1 |
NCT02252094 | Terminated | Ultra-protective Pulmonary Ventilation Supported by Low Flow ECCO2R for Severe ARDS | N/A | Interventional | Device no longer available in Singapore | Actual 8 |
NCT03179605 | Terminated | Assess the Potential for Adrenal Suppression and Systemic Drug Absorption Following Multiple Dosing With DFD-06 | Phase 2 | Interventional | Difficulty in enrollment | Actual 22 |
NCT03192995 | Terminated | Treatment With Lorcaserin for Cocaine Use: The TLC Study | Phase 2 | Interventional | FDA alert regarding study drug safety | Actual 22 |
NCT03328741 | Suspended | Evaluation of a Web-based Platform for Osteoarthritis Treatment | N/A | Interventional | COVID-19 | Anticipated 270 |
NCT03438760 | Terminated | Improving STEM Outcomes for Young Children With Language Learning Disabilities | N/A | Interventional | with 2/3 of the data collected, we had to terminate the study because of COVID19. | Actual 36 |
NCT03537716 | Withdrawn | Fat Reduction Induced by Magnetic Device - Ultrasonographic Evaluation | N/A | Interventional | It wasn't possible to recruit the desired number of patients. | Actual 0 |
NCT03545633 | Withdrawn | Changes in Abdominal Tissues Induced by Magnetic Device - MRI Evaluation | N/A | Interventional | It wasn't possible to recruit the desired number of patients. | Actual 0 |
NCT03545646 | Withdrawn | Changes in Abdominal Tissues Induced by Magnetic Device - CT Evaluation | N/A | Interventional | It wasn't possible to recruit the desired number of patients. | Actual 0 |
NCT03547934 | Withdrawn | Fat Reduction Induced by Magnetic Device - Waist Circumference Evaluation | N/A | Interventional | It wasn't possible to recruit the desired number of patients. | Actual 0 |
NCT03728855 | Terminated | Effects of Self-administration of Medication During Hospitalization on Medication Safety, Adherence, and Patient Satisfaction in Dutch Hospitals | N/A | Interventional | Difficult recruitment, despite several interventions. | Actual 193 |
NCT04008459 | Terminated | Walking and Balance Related to Sagittal Spinal Posture Alignment | Observational | Recruitment no longer viable as spinal classes were stopped due to the COVID-19 situation. | Actual 41 | |
NCT04044326 | Withdrawn | The Safety and Efficacy of Spherical Microwave Ablation for the Treatment of Malignant Liver Tumors | N/A | Interventional | Machine cannot provide | Actual 0 |
NCT04062383 | Suspended | Positive Emotions After Acute Coronary Events at Northwestern University | N/A | Interventional | In-person recruitment suspended due to COVID | Anticipated 10 |
NCT04361916 | Terminated | Home Care for Patients With COVID-19: Active Monitoring in Two Italian Health Units (Casale Monferrato and Torino) | N/A | Interventional | interrupted early due to the drastic reduction in the number of cases | Actual 37 |
NCT04394286 | Suspended | A Phase 1/2 Study of SHP648, an Adeno-Associated Viral Vector for Gene Transfer in Hemophilia B Subjects | Phase 1/Phase 2 | Interventional | Reevaluation of development strategy | Anticipated 21 |
NCT04402580 | Terminated | Efficacy of Anti-CD20 Antibodies (Rituximab Biosimilar) in the Treatment of Childhood Steroid-dependent Nephrotic Syndrome | Phase 2 | Interventional | due to unexpectedly high rate of relapse in the active comparator arm. | Actual 30 |
NCT04440488 | Withdrawn | ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study | Phase 4 | Interventional | Reevaluation of development strategy | Actual 0 |
NCT02253992 | Terminated | An Investigational Immuno-therapy Study to Determine the Safety of Urelumab Given in Combination With Nivolumab in Solid Tumors and B-cell Non-Hodgkin's Lymphoma | Phase 1/Phase 2 | Interventional | Actual 232 | |
NCT03342326 | Terminated | Lexical Priming by Music in Alzheimer's Disease and Healthy Aging | N/A | Interventional | failure to recruit | Actual 58 |
NCT03399227 | Withdrawn | Liver Transplantation: Skeletal Effects | Observational | no funding | Actual 0 | |
NCT03560232 | Terminated | Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens | Phase 4 | Interventional | Unable to recruit patients in a timely fashion and unable to recruit sufficient patients | Actual 17 |
NCT03624777 | Suspended | Efficacy of the Stroll Safe Outdoor Fall Prevention Program | N/A | Interventional | Currently on hold due to COVID-19 restrictions in community program sites | Anticipated 105 |
NCT03730064 | Suspended | Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression | Early Phase 1 | Interventional | Due to COVID-19 pandemic | Anticipated 3 |
NCT03808935 | Terminated | Cannabis Extract in Refractory Epilepsy Study | Phase 3 | Interventional | Participants are no longer being examined or receiving intervention. | Actual 17 |
NCT03811951 | Terminated | Neuro Biomarkers of Smoking Behavior | Phase 2 | Interventional | Different study initiation | Actual 4 |
NCT03908203 | Withdrawn | Minimally Invasive Surgery Techniques for One-level Degenerative Lumbar Deformities Correction | N/A | Interventional | The Study will be conducted in another research center. The Sponsor has changed. | Actual 0 |
NCT03919214 | Suspended | Hypertension Management in Cancer Patients | N/A | Interventional | Suspended due to Covid-19 | Anticipated 40 |
NCT03959852 | Terminated | Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain | Phase 4 | Interventional | Residency completed. | Actual 6 |
NCT04054687 | Suspended | Intranasal TXA for Anterior Epistaxis in the Emergency Department | Phase 2 | Interventional | Due to coronavirus pandemic | Anticipated 86 |
NCT04137809 | Withdrawn | TREAT Foot Drop After Stroke With Ankle Robot | N/A | Interventional | Study withdrawn due to logistical and safety concerns relating to Covid-19. | Actual 0 |
NCT04141917 | Suspended | Test-and-treat for Influenza in Homeless Shelters | Phase 4 | Interventional | Enrollments on hold until fall flu season. | Anticipated 3200 |
NCT04269317 | Suspended | Clinical Study to Evaluate the Safety and Effectiveness of the Treatment With Tixel C on Acne Scars | N/A | Interventional | Corona Virus delayed opening | Anticipated 44 |
NCT04408846 | Withdrawn | Minimally Invasive Surgery Versus Traditional Open Surgery In The Treatment Of Single Level Lumbar Stenosis | N/A | Interventional | The Study will be conducted in another research center. The Sponsor has changed. | Actual 0 |
NCT02664077 | Terminated | A Study Evaluating Regorafenib Following Completion of Standard Chemotherapy for Patients With Colon Cancer | Phase 3 | Interventional | Due to the significantly lower than expected accrual it was impossible to evaluate the endpoint in a timely fashion. | Actual 34 |
NCT04091594 | Suspended | Investigating the Effects of Sensory Input Orthotics in Disorders of Posture and Movement | N/A | Interventional | PI seeking alternative funding for the study | Anticipated 50 |
NCT02353780 | Terminated | Mechanistic Studies of B- and T-Cell Function in RA Patients Treated With TNF Antagonists, Tocilizumab, or Abatacept | Phase 4 | Interventional | Low enrollment | Actual 10 |
NCT01030471 | Withdrawn | Supporting Treatment Adherence Needs in Diabetes | N/A | Interventional | Actual 0 | |
NCT01703338 | Terminated | Clinical and Biomechanics Research in Core Muscles After Lumbar Fusion Surgery | Observational | Actual 100 | ||
NCT02499627 | Terminated | Bendamustine Plus Brentuximab Vedotin in HL and CD30+ PTCL in First Salvage Setting | Phase 2 | Interventional | expected accrual not reached | Actual 43 |
NCT02932319 | Terminated | Outpatient Foley Catheter for Induction of Labor in Nulliparous for Prolonged Pregnancy | N/A | Interventional | Deficient Inclusions | Actual 43 |
NCT02949661 | Withdrawn | Local Wound Infiltration for Tracheal Reconstruction | N/A | Interventional | Loss of interest in the subject | Actual 0 |
NCT03718455 | Terminated | Evaluation of Magseed as Localization Device for Biopsy Proven Metastatic Axillary Lymph Nodes | N/A | Interventional | Limited operating room availability | Actual 1 |
NCT01948297 | Terminated | Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) Alterations | Phase 1 | Interventional | Actual 77 | |
NCT02336373 | Terminated | Treatment of Hemoglobin SC Disease With Hydroxyurea | Phase 2 | Interventional | low enrollment | Actual 32 |
NCT04204109 | Terminated | Interprofessional Versus Monoprofessional Case-based Learning in Childhood Cancer | N/A | Interventional | Covid 19 and subsequent cancellation of all meeting activity | Actual 49 |
NCT00592306 | Withdrawn | Intraoperative Versus Postoperative Thymoglobulin in Lung Transplantation | Phase 3 | Interventional | lack of enrollment | Actual 0 |
NCT02113280 | Withdrawn | DEMAND - DEgenerative Meniscal Tears - Arthroscopy vs. Dedicated Exercise | N/A | Interventional | Failed funding application. | Actual 0 |
NCT03306693 | Terminated | Educational Intervention to Increase the Emotional Competence of Patients With Oesogastric and Bronchopulmonary Cancers | N/A | Interventional | insufficient inclusions | Actual 23 |
NCT03580798 | Terminated | Ridge Preservation Comparing Simultaneous vs. Delayed Grafting | N/A | Interventional | Not enough patients available | Actual 7 |
NCT03607708 | Suspended | Alternative Treatments To Prevent Cognitive Decline in Older Adults With Depression and Anxiety | N/A | Interventional | COVID-19 | Anticipated 30 |
NCT03612167 | Suspended | Constructing A Model of Health Promotion and Active Aging for Community-Dwelling Older Adults | N/A | Interventional | no funding | Anticipated 150 |
NCT03721315 | Terminated | Health Literacy Activation RCT Among the COPD Patients and Designated Support Dyad | N/A | Interventional | SARS-CoV2 pandemic | Actual 6 |
NCT03778606 | Suspended | Oligosaccharide for Cdiff(+) Heme-onc Patients | N/A | Interventional | Temporarily paused due to COVID-19 and expected to resume. | Anticipated 12 |
NCT03950648 | Withdrawn | Spatial Cognitive Training for Chronic Vestibular Disorders | N/A | Interventional | COVID-19 | Actual 0 |
NCT03956251 | Suspended | Ridge Preservation With Putty Allografts | N/A | Interventional | COVID | Anticipated 30 |
NCT03979066 | Terminated | Study Evaluating NEOadjuvant Immunotherapy in Resectable PANCreatic Ductal Adenocarcinoma | Phase 2 | Interventional | Loss of funding | Actual 1 |
NCT03988842 | Suspended | Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism | Phase 4 | Interventional | COVID-19 pandemic | Actual 4 |
NCT04155268 | Withdrawn | Flotation-REST for Chronic Pain, Stress, and Sleep | N/A | Interventional | Unable to conduct the study due to Covid-19. | Actual 0 |
NCT04162964 | Suspended | Chair Yoga for Stress in Dementia | N/A | Interventional | COVID-19 | Anticipated 40 |
NCT02790996 | Terminated | Neonatal Vancomycin Trial | Phase 2 | Interventional | Planned interim analysis yielded different event rate affecting sample size and ability to recruit sufficient numbers within remaining trial time frame | Actual 242 |
NCT03088735 | Terminated | Transfer Strategy in an Oocyte Donation Programme | N/A | Interventional | Due to the clinically and statistically significant inferior results for the D3 group following evaluation by the institutional review board. | Actual 134 |
NCT02591394 | Terminated | STEPs to Blood Pressure Reduction. | N/A | Interventional | Funding period ended and slow enrollment | Actual 115 |
NCT02928887 | Suspended | Light Therapy in Cardiopulmonary Bypass Surgery | N/A | Interventional | Cardiac surgeon collaborator has left the institution | Anticipated 30 |
NCT02711059 | Withdrawn | Insulin Resistance in Primary Hyperparathyroidism | N/A | Interventional | studien skjuts på framtiden | Actual 0 |
NCT03357133 | Terminated | Tirofiban for Patients Treated With Alteplase | Phase 2/Phase 3 | Interventional | The number and speed of enrollment were significantly less than expected. | Actual 30 |
NCT04148300 | Suspended | The Impact of Oral Health Literacy on Dental Anxiety and Utilization of Oral Health Services | Observational | Due to COVID-19 and lock-down of the university | Actual 550 | |
NCT04546802 | Withdrawn | HepATocellular Cancer Hcv Therapy Study | Phase 3 | Interventional | Recruitment will be too difficult due to available PBS funded treatment and recent Australian clinical guidelines will conflict with the premise of the study. | Actual 0 |
NCT03073850 | Terminated | Antithrombotic Treatment in Patients With Effectively Maintained Sinus Rhythm After Atrial Fibrillation Ablation | Phase 4 | Interventional | Majority of enrolled patients have withdrawn. | Actual 48 |
NCT03204149 | Terminated | Evaluation of Safety of Low Level Laser Device Treatment in Chronic Wounds | N/A | Interventional | Project termination | Actual 5 |
NCT03377751 | Terminated | Does VoltagE Guided Additional Ablation Improve Procedural Outcome of Atrial Fibrillation Ablation? | N/A | Interventional | Majority of enrolled patients have withdrawn. | Actual 20 |
NCT03983070 | Suspended | The Effects of Lower Extremity Blood Flow Restriction Training on Power, and Muscle Size. | N/A | Interventional | Covid-19. No in-person study procedures are currently allowable by the overseeing IRB. | Anticipated 30 |
NCT00891917 | Withdrawn | Liq-NOL Efficacy in Pediatric Patients With Down Syndrome | Phase 2 | Interventional | no funding | Actual 0 |
NCT02434874 | Withdrawn | Sacral Nerve Stimulation to Treat Urgency Urinary Incontinence With Wireless Neuromodulation | N/A | Interventional | Study will no longer take place. | Actual 0 |
NCT03151408 | Terminated | An Efficacy and Safety Study Of Pracinostat In Combination With Azacitidine In Adults With Acute Myeloid Leukemia | Phase 3 | Interventional | The IDMC recommended to stop the study prematurely due to a lack of efficacy. | Actual 406 |
NCT03203837 | Terminated | Biomarker Analyses in Hepatocellular Carcinoma (HCC) Patients Treated With TheraSphere® | Observational | Funding Discontinued due to low accrual rate | Actual 4 | |
NCT03506139 | Withdrawn | Biologically-based Target Volumes to Treat Newly Diagnosed Glioblastoma | Phase 2 | Interventional | Not funded | Actual 0 |
NCT03742180 | Withdrawn | Sublingual Ketorolac Compared to Intranasal Dexmedetomidine for Postoperative Analgesia in Pediatric Patients Undergoing Bilateral Myringotomy | N/A | Interventional | Unavailable drug in Egypt. | Actual 0 |
NCT03896451 | Withdrawn | Comparison Between Two Total Knee Prosthesis Medacta GMK Sphere and Medacta GMK PS | N/A | Interventional | Medacta GMK PS is not in use anymore | Actual 0 |
NCT04097496 | Terminated | Effects of ACT OUT! Social Issue Theater on Youth and Adolescents | N/A | Interventional | COVID-19 pandemic and related school policies. | Actual 1537 |
NCT04122183 | Suspended | Internet Auditory Rehabilitation: Follow-up to Adult Hearing Screening | N/A | Interventional | Subject contact has been suspended until it is safe to screen hearing and participants feel safe seeing clinicians. | Anticipated 40 |
NCT03213665 | Suspended | Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial) | Phase 2 | Interventional | Scheduled Interim Monitoring | Anticipated 49 |
NCT04136561 | Withdrawn | Novel Strategy to Encourage Early Removal of Central Venous Catheters | N/A | Interventional | No participants enrolled. Unable to enroll | Actual 0 |
NCT02943447 | Terminated | Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis | Phase 2 | Interventional | The study was terminated because of the availability of alternate therapies for primary biliary cholangitis (PBC). | Actual 71 |
NCT00894361 | Terminated | Comparison of Mobile-Bearing and Fixed-Bearing All-Polyethylene Tibia Total Knee Designs | Phase 4 | Interventional | PI/study coordinator retired due to personal family health matters; study sponsor withdrew funding. Study terminated and no data collected or analyzed | Actual 400 |
NCT00979147 | Terminated | Comparison of a Metal Backed Fixed-Bearing Tibial Baseplate and an All-Polyethylene Tibia in Total Knee Arthroplasty | N/A | Interventional | PI/study coordinator retired due to personal family health matters; study sponsor withdrew funding. Study terminated and no data collected or analyzed | Actual 400 |
NCT01113658 | Withdrawn | Clinical Evaluation of the SNaP Wound Care System | N/A | Interventional | The study was terminated by Spiracur (original sponsor). Efforts were made to contact the PI/study team members, but were unsuccessful. | Actual 0 |
NCT01349894 | Withdrawn | SNaP Wound Care System Over Skin Cancer Excision Sites and Split Thickness Skin Grafts (STSGs) | Observational | The study was terminated by Spiracur (original sponsor). Efforts were made to contact the PI/study team members, but were unsuccessful. | Actual 0 | |
NCT01417208 | Withdrawn | Clinical Evaluation of the SNaP Wound Care System in Promoting Healing in Chronic Wounds | Observational | The study was terminated by Spiraur (original sponsor). Efforts were made to contact the PI/study team members, but were unsuccessful. | Actual 0 | |
NCT01623882 | Withdrawn | Clinical Evaluation of the Combined Use of Apligraf® and the SNaP® Pressure Wound Therapy System | Observational | The study was terminated by Spiracur (original sponsor). Efforts were made to contact the PI/study team members, but were unsuccessful. | Actual 0 | |
NCT02051764 | Terminated | Imaging Characteristics of a Follow-up 18F-AV-1451 Scan | Phase 2 | Interventional | Lower than expected enrollment | Actual 44 |
NCT02192359 | Suspended | Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas | Phase 1 | Interventional | Drug not available. | Anticipated 53 |
NCT03088930 | Withdrawn | Evaluating Crizotinib in the Neoadjuvant Setting in Patients With Non-small Cell Lung Cancer | Phase 2 | Interventional | Low Accrual | Actual 0 |
NCT03120793 | Terminated | ARDS Esophageal Balloon Pressure Changes With Positioning Study | Observational | Failure to recruit/enroll | Actual 2 | |
NCT03133897 | Terminated | Dexamethasone Versus Prednisone for Asthma Treatment in the Pediatric Inpatient Population; a Feasibility Study | Phase 3 | Interventional | it was felt by the sponsoring institution that the current standard of oversight expected by the Health Canada regulations, would not be possible to achieve | Actual 20 |
NCT02772809 | Terminated | Usability Testing of Affordable Haptic Robots for Stroke Therapy | N/A | Interventional | The robot was no longer available to the study. | Actual 23 |
NCT03615924 | Terminated | Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease | Phase 3 | Interventional | Recommendation from an independent data monitoring committee (DMC) and accepted by AstraZeneca. | Actual 193 |
NCT03657095 | Terminated | A Study With BPS-314d-MR-PAH-303 in Participants With Pulmonary Arterial Hypertension | Phase 3 | Interventional | The pivotal study, BPS-314d-MR-PAH-302 (NCT01908699), failed to demonstrate efficacy. | Actual 112 |
NCT03711786 | Suspended | The Sub-Saharan Africa Regional Partnership for Mental Health Capacity Building | N/A | Interventional | COVID-19 - pause in in-person enrollment; follow-up by phone continuing | Anticipated 1160 |
NCT03750656 | Terminated | Use of Hyoscyamine Versus Tamsulosin for Management of Ureteral Stent Irritation | Phase 4 | Interventional | Not accruing patients quickly enough | Actual 6 |
NCT03862027 | Terminated | Evaluating Safety of Transpulmonary Pressure Guided PEEP Management in Neurocritical Care Patients | N/A | Interventional | Failure to enroll/recruit | Actual 2 |
NCT03985215 | Withdrawn | The Value of Follow-Up After Childhood Acute Lymphoblastic Leukaemia in Denmark - Family Perspectives | Observational | Overlapping with another danish questionnaire study | Actual 0 | |
NCT04013763 | Terminated | Outcome of Specific IgE Level in Children With IgE-mediated Wheat Allergy After Stop Using Wheat Containing Skin Care | N/A | Interventional | 1. Limit number of patients during COVID-19 situation 2. Too small number of wheat allergic patients who are using wheat containing soap | Actual 7 |
NCT04048057 | Suspended | The Effect of Different Exercise Programs in Coronary Artery Patients: A Randomized Controlled Study | N/A | Interventional | Because of Covid-19 pandemia, The cardiac rehabilitation unit in the hospital conducting the study has been closed for a while. | Anticipated 60 |
NCT04058145 | Withdrawn | AMD3100 Plus Pembrolizumab in Immune Checkpoint Blockade Refractory Head and Neck Squamous Cell Carcinoma | Phase 2 | Interventional | Funding Withdrawn | Actual 0 |
NCT04073407 | Terminated | Study of the Safety and Tolerability of AXA1957 in Adolescent Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD) | N/A | Interventional | Sponsor has determined that information it would have collected would not inform future development of a therapy with AXA 1957 for NAFLD | Actual 9 |
NCT04106843 | Withdrawn | Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers | Phase 2 | Interventional | No Participants Registered | Actual 0 |
NCT03423537 | Terminated | Low-dose HCG as an Adjunct to Ovarian Stimulation in Subfertile Women Undergoing ART | Phase 3 | Interventional | Inability for further recruitment, change of position of the principal investigator, COVID-19 pandemic | Actual 80 |
NCT03535584 | Suspended | Exercise to Treat Frailty and Decreased Physical Function in Transplant Candidates | N/A | Interventional | Due to Covid19 pandemic at this time we are on pause | Anticipated 50 |
NCT03636048 | Terminated | Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC) | N/A | Interventional | not enough participants | Actual 20 |
NCT03691038 | Terminated | Comparison of Conventional Dose Regimen and New Dose Regimen of Pregabalin | N/A | Interventional | Participants couldn't be enrolled due to complain of frequent visit. | Actual 10 |
NCT03768726 | Terminated | Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder | Phase 3 | Interventional | Pfizer has decided to perform the pre-specified final analysis at the current enrollment using a re-estimation of the sample size. | Actual 23 |
NCT04084574 | Suspended | Diet and Hypertension Management in African Americans With Chronic Kidney Disease | N/A | Interventional | Aim 1 enrollment and study activities have been completed. Aim 2 anticipated start date is 3/2021. | Anticipated 50 |
NCT04175717 | Terminated | Feasibility of a Physiotherapy-led Follow-up Programme in Adult Critical Illness Survivors | N/A | Interventional | Due to COVID pandemic | Actual 3 |
NCT04249713 | Withdrawn | An Alternative Dose Interval Study in Participants With Hidradenitis Suppurativa Receiving Brodalumab | Early Phase 1 | Interventional | Biomarker Samples Not Collected | Actual 0 |
NCT04249947 | Suspended | P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Phase 1 | Interventional | FDA Clinical Hold | Anticipated 40 |
NCT04254666 | Suspended | New Skills - No Scores Research Study | N/A | Interventional | The COVID-19 pandemic required that we discontinue the study. | Anticipated 30 |
NCT04377165 | Terminated | Innovative Tool to Limit Spread of SARS-CoV-2 in Residential Aged Care Facilities | N/A | Interventional | Engagement issues, poor recruitment to study | Actual 34 |
NCT04392128 | Withdrawn | Study Evaluating the Efficacy of Hydroxychloroquine and Azithromycine in Patients With COVID-19 and Hematological Malignancies (HYACINTHE) | Phase 2 | Interventional | competent authority decision | Actual 0 |
NCT04541719 | Withdrawn | Patient Controlled Remifentanil Analgesia for Normal Labour | Phase 2 | Interventional | no participants enrolled | Actual 0 |
NCT03008616 | Terminated | Study of the Efficacy and Safety of AMAG-423 (Digoxin Immune Fab) in Antepartum Subjects With Severe Preeclampsia | Phase 2/Phase 3 | Interventional | Following a recommendation from the Data and Safety Monitoring Board (DSMB), the study was stopped early for futility. There were no safety concerns raised. | Actual 59 |
NCT03473665 | Terminated | Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis | Phase 4 | Interventional | Slow recruitment | Actual 9 |
NCT01571791 | Suspended | Perioperative Ketorolac-lidocaine in the Patients With Valvular Heart Diseases During Cesarean Delivery | Phase 2 | Interventional | No enough recruited cases | Anticipated 90 |
NCT01718756 | Suspended | Continuous Lornoxicam Infusion for Orthopaedic Surgery | Phase 1/Phase 2 | Interventional | No enough fund or cases | Anticipated 96 |
NCT01861561 | Terminated | Low-dose VS High-dose IV Cyclophosphamide for Proliferative LN in Children | Phase 4 | Interventional | The duration of the study is longer than 5 years and we can not recruit the participants to the target number. | Actual 43 |
NCT01937884 | Terminated | Supplemental Parenteral Nutrition in Pediatric Respiratory Failure | Phase 2 | Interventional | Unable to enroll patients | Actual 18 |
NCT01945229 | Terminated | Thumb-ECG Ambulant Screening for Atrial Fibrillation in Patients Treated for Hyperthyroidism (TAMBOURINE) | Observational | Preliminary analyses of data indicated study should be terminated for futility | Actual 110 | |
NCT02420652 | Terminated | Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy | Phase 2 | Interventional | Slow accrual | Actual 27 |
NCT02432378 | Suspended | Intensive Locoregional Chemoimmunotherapy for Recurrent Ovarian Cancer Plus Intranodal DC Vaccines | Phase 1/Phase 2 | Interventional | Anticipated 25 | |
NCT02607488 | Suspended | Perioperative Systemic Lidocaine for Enhanced Bowel Recovery After Bariatric Surgery | Phase 1/Phase 2 | Interventional | No fund no enough recruiting centers | Anticipated 180 |
NCT01799889 | Terminated | Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic Malignancies | Phase 2 | Interventional | Sponsor's decision to discontinue development of entospletinib. | Actual 326 |
NCT03523091 | Terminated | OnabotulinumtoxinA Bladder Injection Study | Phase 4 | Interventional | Lack of enrollment | Actual 1 |
NCT02757976 | Terminated | Resynchronization for Ambulatory Heart Failure Trial - LV Endocardial | N/A | Interventional | Consensus RAFT-LVendo Steering Committee to terminate. | Actual 8 |
NCT03909867 | Suspended | Emission Patterns of Respiratory Syncytial Virus | Observational | The emergence of SARS-CoV-2 required a temporary hold of recruitment | Anticipated 29 | |
NCT03015051 | Terminated | High Flow Nasal Cannula vs Low Flow Oxygen Therapy in Bronchiolitis | Phase 4 | Interventional | Difficulty in recruiting subjects who meet the inclusion/exclusion criteria | Actual 30 |
NCT03106597 | Terminated | Manidipine Versus Amlodipine in Patients With Hypertension | Phase 4 | Interventional | Difficulty in enrolling subjects | Actual 46 |
NCT03221166 | Terminated | Thalidomide Versus Infliximab in New Onset Crohn's Disease With Poor Prognostic Factors | Phase 3 | Interventional | Difficulty in recruiting subjects who meet the inclusion/exclusion criteria | Actual 9 |
NCT04097093 | Withdrawn | Long-term Surival of GIST Patients ≥ 10 Years on Imatinib | Observational [Patient Registry] | Lack of feasibility | Actual 0 | |
NCT02219334 | Terminated | Comparing Nasal Suction Devices in Children With Bronchiolitis: A Pilot Study | N/A | Interventional | The study was stopped due to low enrollment. | Actual 55 |
NCT02429934 | Terminated | Abatacept for SLE Arthritis (IM101-330) | Phase 1/Phase 2 | Interventional | Response rate in placebo group for primary outcome was 100% on interim analysis. | Actual 28 |
NCT02507986 | Suspended | Mobile Phones in Cryptogenic Stroke Patients Bringing Single Lead ECGs to Detect Atrial Fibrillation | N/A | Interventional | no personnel for recruitment | Anticipated 200 |
NCT02577367 | Terminated | Mean Percentage of Levothyroxine Dosage Increase in Patients With Hypothyroidism Started on Enteral Feeding | Phase 4 | Interventional | Hospital has a new protocol holding off feeding 2 hours for LT4 administration. | Actual 4 |
NCT02774551 | Suspended | Physical Activity Intervention Trial to Mitigate Muscle Loss and Increase Muscle Strength | N/A | Interventional | Suspended since March 2020 due to the ongoing covid-19 situation | Anticipated 160 |
NCT02964481 | Terminated | Malignant Hyperthermia Registry and Genetic Testing | Observational | Lack of funding to enroll additional participants | Actual 64 | |
NCT03060954 | Terminated | Non-Inferiority Study Comparing MINI WELL READY® and FineVision® in Patients With Cataract Surgery | N/A | Interventional | The clinical study is closed to further enrolment based on the lack of perceived need to compare the study device with the control device. | Actual 8 |
NCT03589755 | Withdrawn | The Impact of Mindfulness Meditation in Veterans With Epilepsy | N/A | Interventional | unable to recruit enough candidates | Actual 0 |
NCT03597282 | Terminated | A Personal Cancer Vaccine (NEO-PV-01) and APX005M or Ipilimumab With Nivolumab in Patients With Advanced Melanoma | Phase 1 | Interventional | Closed due to historically slow enrollment compounded by the COVID-19 pandemic. | Actual 22 |
NCT03682367 | Terminated | Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery | Phase 3 | Interventional | Poor Recruitment | Actual 10 |
NCT03821649 | Suspended | SOONER Feasibility Study Protocol | N/A | Interventional | Suspended due to non-essential research prohibitions at the study's recruitment and outcome assessment sites in the context of COVID-19. | Anticipated 80 |
NCT03907202 | Terminated | A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM | Phase 1 | Interventional | The trial was planned to be conducted in 4 cohorts but was terminated after completion of Cohort 2 for strategic reasons due to limited PD effects. | Actual 25 |
NCT03978884 | Withdrawn | Phase 4 Study of the Efficacy of Losartan Based Therapy in Hypertensives With and Without Diabetes | Phase 4 | Interventional | Unable to effective arrange trial logistics | Actual 0 |
NCT04093115 | Withdrawn | Study of CX1106 in Patients With Advanced Head and Neck Squamous Cell Carcinoma | Phase 2 | Interventional | The study was terminated voluntarily by the sponsor due to changes in clinical development strategy. | Actual 0 |
NCT04130906 | Suspended | Theta Burst Stimulation in Binge Eating Disorder: A Single Session RCT | N/A | Interventional | The study includes adults vulnerable to COVID-19 and procedures cannot accommodate social distancing. | Anticipated 66 |
NCT04138602 | Withdrawn | BTL Emsella Chair Versus Sham for the Treatment of Fecal Incontinence | N/A | Interventional | Lack of enrollment | Actual 0 |
NCT04143490 | Suspended | Effects of Exercise in Patients With Ulcerative Colitis | N/A | Interventional | Due to Covid-19 | Anticipated 24 |
NCT04206800 | Terminated | Effect of Ejaculatory Abstinence on Semen Parameters in Male Factor Infertility Patients | N/A | Interventional | Difficulty in enrolling participants | Actual 5 |
NCT04228549 | Suspended | MyPADMGT Support of Out-Patients With Peripheral Arterial Disease | N/A | Interventional | Outpatient clinic site suspended temporarily due to COVID 19 virus | Anticipated 210 |
NCT04244825 | Suspended | Safety, Pharmacodynamics, and Pharmacokinetics of Orally Administered BLD-2660 in Subjects With IPF | Phase 2 | Interventional | Suspended due to concerns for patient safety during COVID-19 crisis | Anticipated 32 |
NCT04291508 | Suspended | Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery | Phase 2 | Interventional | Study put on hold due to CIV-19 pandemic and NHLBI directive for PETAL network to redirect efforts to COVI-19 specific treatment trials. | Anticipated 900 |
NCT04300335 | Suspended | The Feasibility and Effects of Exercise on Patients Suffering From Multiple Myeloma | N/A | Interventional | Due to COVID-19 and the fact that the study participants are part of the "high-risk" population, the start of the recruiting process has been delayed at will. | Anticipated 45 |
NCT04377425 | Withdrawn | COVID-19 Prevalence and Cognitive Deficits in Neurological Patients | Observational | No acute neurological patients presented with concomitant COVID-19 | Actual 0 | |
NCT04430010 | Suspended | Multi-level Determinants of Implementation and Sustainment in the Education Sector | N/A | Interventional | Schools opening remotely has prevented recruitment | Anticipated 588 |
NCT02608944 | Withdrawn | Comparison of Quantitative MRI Perfusion Methods With Quantitative PET Perfusion Imaging | N/A | Interventional | MRI perfusion techniques development took years than expected. | Actual 0 |
NCT02929394 | Terminated | Trabectedin Maintenance Post 1st-line in STS | Phase 3 | Interventional | Poor accrual | Actual 13 |
NCT03124628 | Withdrawn | Effects of Flywheel Exercise on Muscle and Walking Function in Teenagers and Young Adults With Cerebral Palsy | N/A | Interventional | Lack of funding | Actual 0 |
NCT03497598 | Terminated | Preventing Recurrent Urinary Tract Infections With α-D-mannose | Phase 4 | Interventional | not enough patients | Actual 15 |
NCT04540952 | Terminated | Randomized Trial Comparing Fluid Capture Efficiency of Total Capture Drape Versus Standard Drape for Hysteroscopy. | N/A | Interventional | COVID-19 | Actual 68 |
NCT03554356 | Suspended | Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE) | N/A | Interventional | Device modifications required prior to trial proceeding. | Anticipated 70 |
NCT03638596 | Suspended | Leveraging Transdermal Alcohol Monitoring to Reduce Drinking Among DWI Defendants | N/A | Interventional | Suspended enrollment due to pandemic, follow-up visits still ongoing. | Anticipated 440 |
NCT03648619 | Suspended | Automatized "Semi-Whole-Body"-MRI Protocol for Cancer Staging | N/A | Interventional | Insufficient recruitment | Anticipated 50 |
NCT03698838 | Terminated | Myelin Imaging Changes In Patients With Neurosurgical Diseases | Observational | Principal Investigator left Institution | Actual 20 | |
NCT03829618 | Terminated | Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound | Phase 3 | Interventional | COVID lack of cases/recruitment | Actual 29 |
NCT02132598 | Terminated | Trial of Cabozantinib (XL184) in Non-Small Cell Lung Cancer With Brain Metastases | Phase 2 | Interventional | Trial stopped due to slow patient accrual. | Actual 5 |
NCT03833596 | Terminated | Exclusive Enteral Nutrition and Corticosteroids Therapy in Crohn's Disease (EENCD) | Phase 4 | Interventional | Low recruitment | Actual 3 |
NCT03883321 | Terminated | EssaiClinique_CBSM | Observational | few patient feedback and principal investigator disponibility | Actual 25 | |
NCT04037306 | Terminated | Measurements From Stool to Support Dietary Change | N/A | Interventional | Weight loss center programming suspended due to COVID-19 pandemic | Actual 7 |
NCT04059666 | Suspended | Gastrointestinal Tract Microbiome in Healthy Term Infants Receiving Mother'S-own Breast Milk or Cow's Milk-based Infant Formulas | N/A | Interventional | COVID-19 | Anticipated 111 |
NCT04170868 | Withdrawn | Psychoeducational Video Series - Proof of Concept | N/A | Interventional | COVID | Actual 0 |
NCT04220788 | Withdrawn | Pharmacist Enhanced Service for Cardiovascular Risk Reduction | N/A | Interventional | No enrollment due to difficulty in recruitment of study sites | Actual 0 |
NCT04325061 | Suspended | Efficacy of Dexamethasone Treatment for Patients With ARDS Caused by COVID-19 | Phase 4 | Interventional | Lack of enrollment | Anticipated 200 |
NCT04326075 | Suspended | Early CPAP in COVID-19 Patients With Respiratory Failure. | N/A | Interventional | the insurance contract hasn't been drafted yet | Anticipated 900 |
NCT04350086 | Withdrawn | Use of Dexmedetomidine in Light to Moderate Sedation in the Patient in the Palliative Situation of a Sars-cov-2 / COVID-19 Infection | Phase 4 | Interventional | unfavorable opinion of the ethics committee | Actual 0 |
NCT04360135 | Suspended | Preemptive Acetaminophen for Postoperative Pain Control Following Minimally Invasive Hysterectomy | Phase 2/Phase 3 | Interventional | PI has decided to put this study on hold at this time. | Actual 208 |
NCT03613831 | Withdrawn | Multi-center Complex Atrial Tachycardia High-Resolution Mapping Registry (MATH) | Observational | The sponsor has decided to stop the study | Actual 0 | |
NCT00603941 | Terminated | A Phase 1/2 Study of CS7017, an Oral PPARγ Agonist, in Combination With Paclitaxel | Phase 1/Phase 2 | Interventional | Due to low enrollment, no participant had a dose limiting toxicity, therefore a maximum tolerated dose could not be established | Actual 19 |
NCT03953352 | Withdrawn | Evaluation of the Automatic Deformable Recontouring on the Daily MVCT for Head and Neck Cancer Adaptive Radiotherapy | N/A | Interventional | Study cancelled | Actual 0 |
NCT00182455 | Terminated | Efficacy of Adding Topiramate to Current Treatment in Treatment-Resistant Generalized Social Phobia (GSP) | Phase 4 | Interventional | loss of funding | Anticipated 12 |
NCT00936234 | Withdrawn | Functional Improvement of Progenitor Cells and Endothelial Function by Vildagliptin in Diabetes Mellitus (FINNjA-DM). | Phase 2/Phase 3 | Interventional | insufficient recruitment | Actual 0 |
NCT00975468 | Suspended | Pressure-Controlled vs Volume-Controlled Ventilation During One Lung Ventilation | N/A | Interventional | Financial shortages due to lack of funderx | Anticipated 40 |
NCT01232153 | Withdrawn | Preoxygenation Before Prehospital Tracheal Intubation With NIV Versus Balloon | N/A | Interventional | departure without replacement of the principal investigator | Actual 0 |
NCT01539395 | Withdrawn | A Cross-Sectional Study of MSDx Complex 1 as a Marker for Active Disease in Multiple Sclerosis | Observational | Actual 0 | ||
NCT02859844 | Terminated | Transcutaneous Tibial Nerve Stimulation for Treating Neurogenic Lower Urinary Tract Dysfunction | N/A | Interventional | Termination after a few pilot participants due to further protocol development | Actual 9 |
NCT03522480 | Withdrawn | The Effectiveness of the Jamboxx Respiratory Therapy Device: Study 2 | N/A | Interventional | Change of Research Objectives for Grant Funded Study | Actual 0 |
NCT03527550 | Suspended | Cognitive Control Training for Urgency in a Naturalistic Clinical Setting | N/A | Interventional | Recruitment paused due to COVID-19 | Anticipated 90 |
NCT03530605 | Withdrawn | Use of Optune TTF With Radiation as an Alternative for Elderly Patients With Primary CNS Lymphoma | N/A | Interventional | Study never initiated, PI left institution | Actual 0 |
NCT03547349 | Suspended | The Effectiveness of the Jamboxx Respiratory Therapy Device: Study 3 | N/A | Interventional | COVID-19 | Anticipated 169 |
NCT03047213 | Suspended | Sapanisertib in Treating Patients With Locally Advanced or Metastatic Bladder Cancer With TSC1 and/or TSC2 Mutations | Phase 2 | Interventional | Other - TSC1/TSC2 testing issues and futility analysis | Anticipated 209 |
NCT03836482 | Suspended | Selective Cytopheretic Device (SCD) Trial | N/A | Interventional | Study halted temporarily to obtain protocol amendment approval but potentially will resume. | Anticipated 10 |
NCT04101006 | Terminated | Perioperative Changes of Cerebrovascular Autoregulation and Association With Cognitive Function | Observational | recruitment difficulties, high postoperative drop-out rate | Actual 78 | |
NCT04538196 | Withdrawn | Coding Improvement Project: Resident Education on Documentation | N/A | Interventional | Study staffing constraints | Actual 0 |
NCT02640690 | Suspended | Trauma-Sensitive Yoga for Female Veterans With PTSD Who Experienced Military Sexual Trauma | N/A | Interventional | Recruitment has been suspended because of COVID related restrictions and limitations imposed on data collection | Anticipated 210 |
NCT02949843 | Terminated | Targeted Therapy in Treating Patients With Incurable Non-Small Cell Lung Cancer With Genetic Mutations | Phase 2 | Interventional | Slow accrual, closed by IRB | Actual 19 |
NCT03106571 | Terminated | Study of Pomaglumetad and Methamphetamine | Phase 1 | Interventional | Deemed unable to enroll targeted participants in part due to COVID-19 shut downs | Actual 19 |
NCT03515200 | Terminated | Treatment With Combination Chemotherapy for Relapsed or Refractory Acute Lymphoblastic Leukemia | Phase 1 | Interventional | Due to departure of PI from St. Jude | Actual 12 |
NCT03648047 | Terminated | Digital Biofeedback System Versus Conventional Rehabilitation After Rotator Cuff Repair | N/A | Interventional | COVID-19 pandemic imposed restrictions to normal study conduct | Actual 50 |
NCT04163224 | Withdrawn | Minimal Invasive Approach for Surgical Repair of Rib Fractures With a Novel Intrathoracic Device | Observational | Sponsor strategy change | Actual 0 | |
NCT01784861 | Terminated | VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Everolimus for Treating Patients With Pancreatic Neuroendocrine Tumors | Phase 1/Phase 2 | Interventional | Pharmaceutical company decision | Actual 23 |
NCT02154984 | Terminated | Time Restricted Diet in Obese or Overweight Pre or Postmenopausal Participants | N/A | Interventional | Study closed due to funding before accrual was met | Actual 45 |
NCT02349633 | Terminated | Study For Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M) | Phase 2 | Interventional | The study was ended for strategic reasons and changes in the external environment. The safety profile and risk benefit ratio for PF-0674775 remained unchanged. | Actual 65 |
NCT02820077 | Terminated | Hemostatic Powder Versus Clinical Management for the Treatment of Upper Gastrointestinal Bleeding From Tumor Lesions | N/A | Interventional | Global recall of Hemospray | Actual 62 |
NCT03362593 | Terminated | A 6-Part Study In Healthy Volunteers To Evaluate Safety, Tolerability and Uptake Of MEDI7219 in the Body When Given as Single and Multiple Doses | Phase 1 | Interventional | The program is canceled due to company strategic reasons. | Actual 186 |
NCT03780205 | Terminated | Bilateral and Unilateral Amblyopia Treatment Study | Observational | Unable to recruit sufficient number of subjects | Actual 1 | |
NCT03877250 | Withdrawn | Analysis of Biopsy Specimens to Study Responses to PD-1 or PD-L1 Therapies | Observational | The primary objectives have not been met due to no patient enrollment therefore, the PI is requesting to close the study at this time. | Actual 0 | |
NCT03953456 | Terminated | Study to Evaluate the Effect of Elafibranor on Hepatic Lipid Composition in Subjects With Nonalcoholic Fatty Liver (NAFL) | Phase 2 | Interventional | Continuation of the trial cannot serve a scientific purpose | Actual 17 |
NCT04075071 | Terminated | A Pilot Study of Teacher-Child Interaction Training - Universal in Head Start | N/A | Interventional | Intervention and and final data collection point was not completed due to coronavirus school closures in March 2020. | Actual 70 |
NCT00586209 | Terminated | L-Glutamine Therapy for Sickle Cell Anemia | Phase 2 | Interventional | Due to inadequate supplies of study drug & internal business decisions. | Actual 15 |
NCT02975336 | Terminated | A Phase II Study of M2951 in Systemic Lupus Erythematosus (SLE) | Phase 2 | Interventional | Study is completed; primary analysis completed. | Actual 480 |
NCT03237754 | Terminated | Neurostimulation in Chronic and Episodic Migraine | N/A | Interventional | Recruitment problems (especially for chronic migraine patients) | Actual 41 |
NCT03540368 | Suspended | Tranexamic Acid for The Treatment of Gastrointestinal Bleeding | N/A | Interventional | increased number of patients death | Anticipated 336 |
NCT03607500 | Suspended | Effect of Moderate Caloric Restriction on Glomerular Growth After Kidney Transplantation | N/A | Interventional | Lack of funding | Anticipated 30 |
NCT03752242 | Suspended | Evaluation of Topical Application of BMX-010 in Subjects With Acne Vulgaris. | Phase 2 | Interventional | Enrollment stopped for chemistry work on investigational product. | Actual 2 |
NCT03825913 | Terminated | 3-month Aerobic and Resistance Exercise Intervention for Individuals Diagnosed With Melanoma | N/A | Interventional | two key faculty members are no longer part of the study and institution | Actual 1 |
NCT03889873 | Suspended | Evaluating Change in Drinking Identity as a Mechanism for Reducing Hazardous Drinking - Study 2 | N/A | Interventional | Paused enrollment due to COVID-19 pandemic; will resume Fall 2020 | Anticipated 328 |
NCT04118569 | Suspended | Personalized Experiences to Inform Improved Communication for Patients With Life Limiting Illness | N/A | Interventional | On hold due to COVID-19 pandemic. | Anticipated 80 |
NCT04349228 | Withdrawn | Assessment of the Efficacy and Safety of (HCQ) as a Prophylaxis for COVID19 for Health Professionals | Phase 3 | Interventional | - Interest in the use of HCQ is controversial. | Actual 0 |
NCT04351919 | Withdrawn | Assessment of Efficacy and Safety of HCQ and Antibiotics Administrated to Patients COVID19(+) | Phase 4 | Interventional | - Interest in the use of HCQ is controversial. | Actual 0 |
NCT03249272 | Terminated | Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve | Phase 4 | Interventional | Sponsor withdrew funding | Actual 31 |
NCT04386434 | Withdrawn | Active for Life Assisted Living Feasibility and Acceptability Study | N/A | Interventional | Pandemic, researchers no longer have access to residents of assisted living. | Actual 0 |
NCT03871569 | Terminated | Medico-economical Evaluation on Buccodental Teleexpertise in Nursing Home | N/A | Interventional | Difficulty recruiting and follow-up due to the epidemic context of COVID19 | Actual 171 |
NCT04528927 | Withdrawn | Evaluation of the Efficacy and Safety of Treatments for Patients Hospitalized for COVID-19 Infection Without Signs of Acute Respiratory Failure, in Tunisia | Phase 3 | Interventional | - Interest in the use of HCQ is controversial. | Actual 0 |
NCT00860379 | Terminated | The Effect of Selenium Supplementation Among Pediatric Patients With Burns | Phase 4 | Interventional | Due to a shift in primary responsibilities, the PI was not longer able to enroll subjects. | Actual 14 |
NCT02429505 | Withdrawn | Treatment of Leishmaniasis With Impavido® (Miltefosine): Higher-Weight Patient Registry | Observational [Patient Registry] | This study was COMPLETED, but no patients were enrolled. | Actual 0 | |
NCT01334489 | Terminated | The Trial of Pessary After Laser for TTTS | N/A | Interventional | Interim analysis unfavorable to continue the study | Actual 352 |
NCT01535157 | Terminated | Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer | Phase 1/Phase 2 | Interventional | drug combination not providing any efficacy. Will use this data in opening new trial | Actual 12 |
NCT02090868 | Withdrawn | An Oral Intake Screening Tool for Patients Receiving Non-Invasive Ventilation | Observational | No patients recruited due to decreased levels of patients requiring non-invasive ventilation during the study. | Actual 0 | |
NCT02759120 | Terminated | CleanUP IPF for the Pulmonary Trials Cooperative | Phase 3 | Interventional | Terminated for futility after review of first planned interim analysis. | Actual 509 |
NCT02810236 | Suspended | Focal Breast Pain: Does a Normal Ultrasound Provide Reassurance? | N/A | Interventional | The study is suspended due to the pandemic | Anticipated 160 |
NCT02874820 | Terminated | I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD | Early Phase 1 | Interventional | Patient recruitment issues. | Actual 2 |
NCT02927470 | Withdrawn | TMS of Visual Working Memory | N/A | Interventional | Investigators are no longer at NYU Langone Health | Actual 0 |
NCT03036891 | Withdrawn | Naloxegol for Opioid-Related Gastroparesis | Phase 2 | Interventional | Actual 0 | |
NCT03556930 | Withdrawn | Simulated Radiotherapy Treatment Assisted With Pediatric Radiation Oncology With Movie Induced Sedation Effect Technique | Early Phase 1 | Interventional | Project was never initiated. | Actual 0 |
NCT03693274 | Terminated | Mindfulness to Improve Functional Outcomes in Patients With Fibromyalgia or Central Sensitization | N/A | Interventional | Principal investigator leaving institution. | Actual 16 |
NCT04374474 | Withdrawn | Anosmia Rehabilitation in Patients Post Coronavirus Disease (COVID 19) | Phase 4 | Interventional | Study withdrawn before any enrollment (site's research goals adjustments). | Actual 0 |
NCT04384614 | Withdrawn | Covid-19 In Tunisia: An Observational Cross-Sectional Registry Study | Observational [Patient Registry] | The sponsor decided to withdraw the study for funding reasons. | Actual 0 | |
NCT04527796 | Terminated | Influence of a Residential Rehabilitation Program on Body Composition in Patients With Cystic Fibrosis | N/A | Interventional | number included | Actual 39 |
NCT02315625 | Terminated | Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery | Phase 2 | Interventional | Study closed due to poor accrual. | Actual 16 |
NCT03992079 | Terminated | A Multimodal Enhanced Recovery Program in Anorectal Surgery | N/A | Interventional | PI is no longer at institution | Actual 60 |
NCT04282681 | Withdrawn | XLTCS - Accelerometer Data Collection in an Epilepsy Monitoring Unit (EMU) | Observational | Sponsor decision due to clinical strategy changes | Actual 0 | |
NCT04332341 | Suspended | Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation | Early Phase 1 | Interventional | COVID-19 hold | Anticipated 20 |
NCT02638506 | Terminated | RCT Evaluating Intranasal Fentanyl in the Pain Management of Children With Headaches | Phase 4 | Interventional | Covid restrictions | Actual 60 |
NCT02743169 | Withdrawn | Improvement of Ambulance Response Times in Karachi, Pakistan | Observational | Could not acquire data | Actual 0 | |
NCT03232632 | Terminated | Assessment of Cardiac Fixation During PET Using a New Drug Within Amyloid Cardiac Injuries. | Early Phase 1 | Interventional | intervention programming | Actual 7 |
NCT03251872 | Terminated | Olaparib for PAH: a Pilot Study | Early Phase 1 | Interventional | OPTION pilot trial merged with the new NCT03782818 - OPTION multicenter trial | Actual 6 |
NCT03289624 | Withdrawn | SHARE for Persons With Chronic Conditions and Their Family Caregivers | N/A | Interventional | Lost Funding | Actual 0 |
NCT03312127 | Terminated | Evaluation of Peri-surgical Results at Short and Mean Terms of the GORE ® Excluder Iliac Branch Endoprosthesis | N/A | Interventional | End of inclusion period | Actual 3 |
NCT03348111 | Withdrawn | Establishing a New Protocol for Early Mucositis and Peri-implantitis Treatment Using an Air-polishing Device | N/A | Interventional | No participant enrolled | Actual 0 |
NCT03738124 | Withdrawn | Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Thoracic Aortic Aneurysms and Chronic Dissections | N/A | Interventional | Production of the medical device was stopped | Actual 0 |
NCT04053543 | Terminated | CXA-10 Study in Subjects With Pulmonary Arterial Hypertension | Phase 2 | Interventional | LOE | Actual 33 |
NCT04066088 | Withdrawn | Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome | Phase 4 | Interventional | PI departure from institution | Actual 0 |
NCT04227938 | Terminated | Study of ALPN-101 in Steroid-resistant or Steroid-refractory Acute GVHD Versus Host Disease | Phase 1 | Interventional | Change in sponsor strategy | Actual 1 |
NCT04317924 | Withdrawn | Pneumostasis With Use of Bio-absorbable Mesh and Fibrin Sealant in Lung Resection | N/A | Interventional | Resources not available to conduct the research. | Actual 0 |
NCT03522805 | Terminated | Impact of Non-invasive Ventilation in Hypercapnic COPD | N/A | Interventional | Failure to accrue subjects. All activity has stopped & no analysis will be done on what has been collected. | Actual 6 |
NCT04142554 | Withdrawn | Parsaclisib in Newly Diagnosed Stage I-IIIC Triple Negative or HER2+ Breast Cancer | Phase 1 | Interventional | Funding withdrawn from funding source. | Actual 0 |
NCT04528758 | Suspended | F-18 Rhodamine 6G PET Imaging for Myocardial Blood Flow | Early Phase 1 | Interventional | re-evaluation of radiotracer | Anticipated 15 |
NCT04438551 | Suspended | Software Application for Low-Sodium Diet Trial (SALT) | N/A | Interventional | Study is on hold until pilot study is completed. | Anticipated 80 |
NCT04403685 | Terminated | Safety and Efficacy of Tocilizumab in Moderate to Severe COVID-19 With Inflammatory Markers | Phase 3 | Interventional | Safety | Actual 129 |
NCT01096290 | Terminated | Comparison of Lubiprostone and Placebo for the Relief of Constipation From Constipating Medications | Phase 4 | Interventional | Number of needed participants could not be obtained | Actual 23 |
NCT02026726 | Terminated | Do Oral Steroid Dose Packs Predict How Well Epidural Steroid Injections Will Work? | Observational | could not recruit | Actual 10 | |
NCT02673151 | Suspended | 68Ga-PSMA PET/CT in Detecting Prostate Cancer Recurrence in Patients With Elevated PSA After Initial Treatment | Phase 2/Phase 3 | Interventional | logistics | Anticipated 200 |
NCT02775422 | Terminated | Comparison of Serological Test s for the Virus Chicken Pox Virus (VZV) and Correlation With the Patient's Memory of the Infection or Vaccination | N/A | Interventional | Low inclusion rate. | Actual 308 |
NCT03202498 | Terminated | Safety and Tolerability of Yaq-001 in Patients With Cirrhosis | N/A | Interventional | COVID-19 pandemic prevents patients from making in-hospital visits, which are mandatory to assessment of safety in this study | Actual 31 |
NCT03665636 | Suspended | Anaplerotic Therapy Using Triheptanoin for Patients With Glycogen Storage Disease Type I | Early Phase 1 | Interventional | due to COVID-19 | Anticipated 5 |
NCT03821766 | Withdrawn | Haemodynamic Abnormalities Recorded With Cardiac Catheterization Along With Body's Surface Micro-accelerometers (KT-KCG) | Observational | Technical failure | Actual 0 | |
NCT03834584 | Terminated | A Study of AG-636 in the Treatment of Subjects With Advanced Lymphoma | Phase 1 | Interventional | Terminated due to sponsor decision. | Actual 11 |
NCT04100681 | Terminated | Intermittent Negative Pressure; Impact on Peripheral Artery Disease and Intermittent Claudication | N/A | Interventional | The study was terminated early due to slow recruitment and inability to recruit patients during the Covid-19 situation. | Actual 16 |
NCT04222985 | Suspended | Safety and Efficacy of 4 Investigational HSV 2 Vaccines in Adults With Recurrent Genital Herpes Caused by HSV 2 | Phase 1/Phase 2 | Interventional | (Enrollment suspended for 1 site due to Covid-19; For the other sites, enrollment completed in Part A and planned to be restarted for Part B at the end of 2022) | Anticipated 381 |
NCT04358835 | Withdrawn | Keto-diet for Intubated Critical Care COVID-19 | N/A | Interventional | Study did not begin enrollment, multiple competing studies at same institution | Actual 0 |
NCT04526236 | Suspended | Influence of Aging on Perioperative Methadone Dosing | Phase 4 | Interventional | pandemia of covid 19 | Anticipated 60 |
NCT01508598 | Terminated | Validation of Circulating Endothelial Cells and Microparticles in Youth | Observational | Not enough subjects enrolled to be able to analyze data. | Actual 390 | |
NCT01977027 | Terminated | Strategies for Recovery of Dexterity Post Stroke | N/A | Interventional | PI left insitution | Actual 91 |
NCT02589314 | Terminated | Effect of Periodontal Therapy in the Systemic Status of Individuals With Chronic Periodontitis and Diabetes Type 2 | Observational | We could not achieve the number of participants necessary to continue with the study and limited money to continue with the study | Actual 90 | |
NCT01055067 | Terminated | ARQ 197 for Participants With Relapsed or Refractory Germ Cell Tumors | Phase 2 | Interventional | The study was terminated early for futility according to the stopping rule of the Simon 2-stage design. | Actual 27 |
NCT02558023 | Terminated | The Treatment of Hypertension Associated With Severe Preeclampsia (PE). A Trial of Urapidil Versus Nicardipine | Phase 3 | Interventional | no candidats | Actual 14 |
NCT02716701 | Terminated | Exercise in Multiple Sclerosis | N/A | Interventional | lack of funding | Anticipated 40 |
NCT02737930 | Terminated | Fluoxetine for Visual Recovery After Ischemic Stroke | Phase 2 | Interventional | Slow recruitment and lack of funding to expand to other sites. | Actual 17 |
NCT03330561 | Suspended | PRS-343 in HER2-Positive Solid Tumors | Phase 1 | Interventional | Partial clinical hold | Anticipated 110 |
NCT03370302 | Terminated | A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of TAK-228 as Single Agent in Adult East Asian Participants With Advanced Nonhematological Malignancies | Phase 1 | Interventional | More favorable safety profile was observed in QD schedule, therefore further enrollment in QW schedule was terminated. | Actual 28 |
NCT04525170 | Withdrawn | Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Hexafocon A | N/A | Interventional | It was decided by the sponsor to not proceed. | Actual 0 |
NCT01864018 | Suspended | Ixazomib Citrate, Cyclophosphamide, and Dexamethasone in Treating Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis | Phase 1/Phase 2 | Interventional | Actual 71 | |
NCT02373540 | Terminated | Algovita Post-Market Clinical Study: Spinal Cord Stimulation to Treat Chronic Pain | Observational | Actual 91 | ||
NCT04522466 | Terminated | Evaluation of the Pharmacokinetics and Pharmacodynamics of Hydroxychloroquine in COVID-19 Intensive Care Unit Patients | Phase 3 | Interventional | Stop of the study by competent authority (ANSM) | Actual 7 |
NCT02266147 | Terminated | Study of SD-101 in Combination With Localized Low-dose Radiation in Patients With Untreated Low-grade B-cell Lymphoma | Phase 1/Phase 2 | Interventional | The sponsor terminated the trial early because there was sufficient data to make a decision about SD-101 in the lymphoma development program. | Actual 29 |
NCT01951378 | Terminated | Comparison of Nebulizers in ED in Pediatric Asthma Patients | Phase 4 | Interventional | No data are available for this study as the PI has left the institution. | Actual 40 |
NCT04275011 | Suspended | Bone Response to Exercise in Women on Antiresorptive Medications | N/A | Interventional | The study has been suspended until further notice due to COVID-19. | Anticipated 46 |
NCT04493697 | Withdrawn | Using Neuromodulation to Improve Parkinson's Disease | N/A | Interventional | Device provider has requested withdrawal citing modifications needed for study integrity. | Actual 0 |
NCT03538015 | Terminated | Carvedilol in Treating Hypoglycemia Unawareness | Phase 2 | Interventional | Sponsor was impacted by COVID-19 and did not have sufficient funds to continue. | Actual 1 |
NCT04520620 | Withdrawn | Concentration-effect Relationship of Enoxaparin for Thromboembolic Prevention | Phase 4 | Interventional | End of the COVID 19 epidemic in the region and decision to participate in a national study on the same subject (COVI-DOSE). | Actual 0 |
NCT00031174 | Terminated | Blood Component Collection From Patients With Rheumatic or Kidney Disease and Healthy Volunteers | Observational | Due to technical and logistical constraints and a change in the study team's focus of research | Actual 151 | |
NCT00756834 | Terminated | Case Collection Study for Collecting Images for the Development and Validation of Computer Aided Detection Software | Observational | No longer pursuing FDA submission/approval. | Actual 135 | |
NCT01213563 | Terminated | Management of Type 2 Diabetes After Gastric Bypass Surgery | N/A | Interventional | Data were published that superseded this study. | Actual 50 |
NCT01391520 | Withdrawn | Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent | Phase 3 | Inte |