Clinical trials stopped by Covid-19

Benjamin Gregory Carlisle PhD

Charité – Universitätsmedizin Berlin, Germany
Berliner Institut für Gesundheitsforschung (BIG) / Berlin Institute of Health (BIH)
QUEST – Quality | Ethics | Open Science | Translation

The Covid-19 outbreak that became a global pandemic in 2020 has disrupted lives, families, industries and entire nations. This project is a daily-updated "living paper" that aims to quantify some of the effects of Covid-19 on the enterprise of human research.

The following table contains all registry entries from ClinicalTrials.gov whose overall status changed to Terminated, Suspended or Withdrawn since 2019-12-01. Investigator-provided reasons that explicitly mention Covid-19 are highlighted in green. Click a row of the table for more details about the trial.

To date, 1473 clinical trials have been stopped due to Covid-19.

These data and figures are available to be downloaded under a Creative Commons By-Attribution Non-Commercial license. This data set was last updated 2020-07-05.

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Covid-19 arm per-trial data set TSV
Comparator arm per-trial data set TSV
Drugs and biologics in stopped trials TSV
NCT ID Overall status Brief title Phase Study type Why stopped Enrollment
NCT04455919 Terminated Yoga for Chronic Chikungunya N/A Interventional covid health crisis Actual 42
NCT04361461 Withdrawn Use of Hydroxychloroquine Alone or Associated for Inpatients With SARS-CoV2 Virus (COVID-19) Phase 3 Interventional This study was canceled before enrollment due to a decision by the Sponsor Actual 0
NCT02600429 Terminated Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic Keratopathy : SEER-1 Phase 3 Interventional Business decision Actual 18
NCT03017105 Terminated Cross-education for Proximal Humerus Fracture Rehabilitation Phase 1/Phase 2 Interventional Logistical difficulties leading to an extremely slow recruitment rate Anticipated 40
NCT03023813 Suspended Individualizing Disease Prevention for Middle-Aged Adults N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 130
NCT03076710 Withdrawn Post-Operative Pain Management Following Spine Surgery Observational No participants were identified per inclusion/exclusion criteria Actual 0
NCT03376399 Withdrawn Potential Benefits of Sleeve Gastrectomy Surgery on Diabetic Gastroparesis Symptoms Observational No participants enrolled. Study terminated at PI's discretion Actual 0
NCT03598907 Terminated Point-of-care Management of Coagulopathy in Lung Transplantation Observational After interim statistical analysis, a statistician reccommended to stop study, because results are significant and in favour of POC approach. Actual 67
NCT03684187 Suspended Mindfulness - Based Intervention in the Treatment of Fatigue in Patients With Primary Biliary Cholangitis N/A Interventional Covid - 19, will resume when able. Anticipated 20
NCT03707457 Terminated Biomarker-Driven Therapy Using Immune Activators With Nivolumab in Patients With First Recurrence of Glioblastoma Phase 1 Interventional Funding/material support withdrawn Actual 3
NCT03890198 Terminated A Phase 1 Study of LCAR-C182A Cells in the Treatment of Advanced Gastric Cancer and Pancreatic Ductal Adenocarcinoma Early Phase 1 Interventional the Preliminary data, progress of this study and the adjustment of the pipeline and strategy . Actual 2
NCT03902275 Terminated Validation of a Quantra Supported Hemotherapy Algorithm in Cardiac Surgery N/A Interventional SARS-CoV-2 Pandemic Actual 20
NCT04051996 Suspended GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia Phase 2 Interventional Temporary Recruitment Hold due to COVID-19 Anticipated 46
NCT04125030 Suspended Convergent and Concurrent Validity Between Clinical Recovery and Personal-civic Recovery in Mental Health Observational [Patient Registry] COVID-19 pandemic Anticipated 200
NCT04132700 Withdrawn Longitudinal Evaluation of Energy Expenditure in ICU Patients From Admission to Discharge Using A Novel Indirect Calorimeter: LEEP-Forward Trial N/A Interventional LEEP-COVID study (NCT04350073) initiation enables inclusion of COVID-positive subjects Actual 0
NCT04395118 Withdrawn STOP HCC: Mailed HCV Treatment Outreach Program for HCC Prevention for Elevated LFTs N/A Interventional Study will not be conducted as a RCT due to limited project timeline. Actual 0
NCT03923348 Terminated Pelvic Floor Muscle Training With Leva System for Urge Incontinence N/A Interventional Slow Recruitment and Re-prioritizing of Sponsor-funding Actual 5
NCT03339921 Terminated Botulinum for Chronic Exertional Compartment Syndrome Phase 2/Phase 3 Interventional This study is being closed because it is unworkable. Actual 3
NCT01089374 Suspended Phyllodes Tumor Partial Breast Radiation Study N/A Interventional continuing review Anticipated 50
NCT02387125 Terminated Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1 Phase 1 Interventional This study did not meet the efficacy objective Actual 79
NCT02485990 Terminated Study of Tremelimumab Alone or Combined With Olaparib for Patients With Persistent EOC (Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma) Phase 1/Phase 2 Interventional Withdrawal of sponsor support Actual 24
NCT02826967 Terminated Feasibility and Effectiveness of Colonic Irrigation N/A Interventional COVID-19 institutional restrictions on screening colonoscopies Actual 36
NCT02847130 Suspended Identifying, Understanding, and Overcoming Barriers to the Use of Clinical Practice Guidelines in Pediatric Oncology Observational Reviewing enrolled patients Anticipated 694
NCT03471559 Terminated Cannabidiol - an in Vivo Innovative Drug Delivery Study Phase 1 Interventional Two step study, step two was not feasible based on results from phase one. Actual 8
NCT04078438 Terminated Neurofeedback In Treatment Resistant Depression N/A Interventional Because of researcher foreign training Actual 70
NCT04146012 Suspended BEACH Trial: Bovine Early Access, Compatibility and Hemostasis Trial Phase 3 Interventional Company was sold and clinical trial was suspended Anticipated 75
NCT03791008 Suspended Assessment of Feasibility and Acceptability of Personalized Breast Cancer Screening N/A Interventional Recrutiment was suspended on March 12, 2020 due to the coronavirus pandemic Anticipated 385
NCT04323631 Withdrawn Hydroxychloroquine for the Treatment of Patients With Mild to Moderate COVID-19 to Prevent Progression to Severe Infection or Death Early Phase 1 Interventional Trial not started due to accumulating evidence against HCQ for COVID Actual 0
NCT04164082 Suspended Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer Phase 2 Interventional Other - Planned safety stopping Anticipated 163
NCT03846492 Suspended Targeting Brain Physiology to Treat Neuropsychiatric Symptoms of Dementia Using TMS-EEG and tDCS N/A Interventional Suspended due to COVID-19 Anticipated 90
NCT00003060 Terminated Chemotherapy Plus Bone Marrow Transplantation in Treating Patients With Metastatic Melanoma Phase 1 Interventional lack of patient accrual Anticipated 6
NCT03396484 Withdrawn Methyldopa for Reduction of DQ8 Antigen Presentation in At-Risk Subjects for Type 1 Diabetes Phase 2 Interventional Study not begun due to continued laboratory work on the feasibility of outcome measures. Actual 0
NCT03944707 Terminated Study of Efficacy and Safety of LOU064 in Inadequately Controlled Asthma Patients Phase 2 Interventional Company decision Actual 76
NCT04020549 Withdrawn Single-Session Computerized Mental Health Intervention for Rural Indian Adolescents N/A Interventional In collaboration with community partners, we determined that the reading level required for the intervention did not make it suitable for the adolescents. Actual 0
NCT04160091 Terminated Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Adhesive Capsulitis Phase 2 Interventional The study was terminated prematurely due to the COVID-19 pandemic creating uncertainty impacting trial progress and costs. Actual 19
NCT04290637 Suspended The Galway Sea Swimmers Study N/A Interventional Unable to recruit during COVID-19 crisis Anticipated 150
NCT04330300 Suspended Coronavirus (COVID-19) ACEi/ARB Investigation Phase 4 Interventional Challenges with funding and very low incidence of COVID-19 at Irish study site Anticipated 2414
NCT01510691 Withdrawn Vitrectomy Retinal Oxygenation Observational Difficulties in recruiting participants Actual 0
NCT02477124 Suspended A See and Treat Paradigm for Cervical Pre-cancer N/A Interventional COVID-19 Anticipated 200
NCT02673021 Terminated MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s) N/A Interventional Funding suspended prior to completing enrollment of all participants. Actual 6
NCT03323645 Terminated Prosthetics Registry and Outcomes in Urology at Duke Observational change of study structure and resource allocation Actual 190
NCT03339973 Terminated Allogeneic ABCB5-positive Stem Cells for Treatment of PAOD Phase 1/Phase 2 Interventional Very slow recruitment of patients and the current COVID-19 pandemic situation. Actual 24
NCT03457818 Terminated Therapy of the Skeletal Disease of Type 2 Diabetes With Denosumab Phase 2 Interventional Due to enrollment difficulties compounded by the COVID pandemic. Actual 8
NCT04409483 Withdrawn Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger Phase 3 Interventional Epidemic dynamics Actual 0
NCT04451382 Terminated PTNS vs Botox of Refractory OAB Observational Low recruitment Actual 150
NCT03143985 Suspended Vactosertib in Combination w/ Pomalidomide in Relapsed or Relapsed and Refractory Multiple Myeloma Phase 1 Interventional Major revisions due Anticipated 18
NCT02985554 Terminated Phase I Study to Assess the Tolerability and Efficacy of Nivolumab in Patients With Hematologic Malignancies Phase 1 Interventional Study stopped early due to slow accrual and safety concerns. Actual 3
NCT01301482 Terminated Ear Acupuncture for Acute Sore Throat in Patients Unable to Take Non-steroidal Anti-inflammatory Agents (NSAIDs) N/A Interventional Study is no longer necessary (outmoded, outdated, science has changed) Actual 2
NCT03020264 Terminated Frequency of Hypoglycemia in Patients With Type 2 Diabetes Under Insulin Therapy Older Than 75 Years in Real Life N/A Interventional COVID-19 Actual 161
NCT03475043 Suspended Neuroplasticity in Auditory Aging_Project 2 N/A Interventional coronavirus pandemic, no human subjects research at UMD Anticipated 405
NCT03868436 Suspended PENTHROX™ in the Canadian Emergency Department (ED) Phase 4 Interventional Recruitment is complete however study suspended due to COVID 19 Actual 99
NCT03910322 Terminated The Effect of a Probiotic Strain on Aspirin-induced GI Damage N/A Interventional Decision made by Sponsor Actual 30
NCT04231682 Withdrawn A Study to Evaluate Efficacy and Safety of Denosumab for Prevention and Treatment of Osteoporosis in 1st Time Liver Transplant Recipients. Phase 2 Interventional Grant support was withdrawn from Amgen Pharmaceuticals Actual 0
NCT04259190 Withdrawn A Comparison of Treatment Rationales on Willingness to Tolerate Distress in Interoceptive Exposure N/A Interventional Halted due to COVID-19. Actual 0
NCT04329403 Withdrawn Clinical Endpoint Bioequivalence Study of Adapalene Gel 0.1% Phase 3 Interventional Market reasons Actual 0
NCT03051698 Terminated C1-inhibitor in Allergic ASThma Patients Phase 4 Interventional Interim analysis showed no differences between groups Actual 37
NCT00839787 Withdrawn The Effect of Pain Medication in Children With Acute Abdominal Pain and Its Implication Over the Surgeon's Decision N/A Interventional Unable to enroll more patients Actual 0
NCT01785069 Terminated Safety and Effectiveness of NATRELLE® 410 Highly Cohesive, Anatomically Shaped, Silicone-filled X-Style and L-Style Breast Implants N/A Interventional There was no indication that long-term follow-up would differ between any of the studies that have evaluated devices within the 410 Style Matrix. Actual 355
NCT03255213 Suspended Lingual Muscle Training in Late-Onset Pompe Disease (LOPD) N/A Interventional Due to COVID19 restrictions Anticipated 5
NCT03488147 Suspended Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery Phase 2 Interventional Change in Investigational Drug Service policies resulting in the need to change the operational design of the overall protocol. Anticipated 500
NCT03567291 Terminated Evaluation of Safety and Tolerability of Long-term TEV-50717 (Deutetrabenazine) for Treatment of Tourette Syndrome in Children and Adolescents Phase 3 Interventional The parent trials did not meet the primary endpoints of reduction in motor and phonic tics. Actual 228
NCT03836885 Withdrawn Apremilast - Oral Lichen Planus Trial Phase 2 Interventional Study was terminated due to delay in enrollment. Actual 0
NCT03890861 Suspended Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)" N/A Interventional Temporarily paused due to COVID-19 and expected to resume. Anticipated 200
NCT04020926 Terminated Impact of Hyponatremia on Muscle Strength, Gait and Cognitive Function Observational Study was stopped due to COVID-19 pandemic. Actual 8
NCT04162145 Terminated BRIDGE Device for Treatment of Opioid Withdrawal N/A Interventional Due to COVID-19 pandemic Actual 12
NCT04177459 Terminated Rehabilitation of Adolescents Living With Chronic Fatigue N/A Interventional Covid-19 Actual 3
NCT04285008 Withdrawn Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation N/A Interventional Sponsor has terminated study due to COVID-19 related concerns Actual 0
NCT04354441 Withdrawn Effect of Hydroxychloroquine in COVID-19 Positive Pregnant Women Phase 2 Interventional Not started Actual 0
NCT03728673 Suspended A Study Utilizing Escitalopram in Glioma Patients Phase 2 Interventional COVID-19 safety precautions Anticipated 20
NCT04449445 Suspended Perioperative Nutritional Optimization in Head and Neck Cancer Patients N/A Interventional COVID-19 Anticipated 300
NCT02351869 Terminated Nitrous Oxide as a Putative Novel Dual-Mechanism Treatment for Bipolar Disorder Phase 2 Interventional This study was terminated due to COVID-19 pandemic-related halting of recruitment in the context of an upcoming replacement of the study MRI scanner. Actual 25
NCT02362191 Terminated Targeting Inter-Hemispheric Alpha Coherence With tACS To Treat PMDD N/A Interventional The study was terminated because the dense treatment schedule precluded successful recruitment of study participants. Actual 13
NCT03082612 Suspended Overcoming Psychological Distress Through Hymns N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Actual 12
NCT03135262 Terminated A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax in Participants With R/R Diffuse Large B-Cell Lymphoma (DLBCL) Phase 1/Phase 2 Interventional Sponsor's decision to terminate the study after Phase 1; will not proceed with Phase 2. Actual 29
NCT03375606 Terminated Assessing the Safety and Tolerability of CSL730 in Healthy Caucasian and Japanese Adults Phase 1 Interventional The Sponsor decided to terminate this study in favor of development of subcutaneous administration. Actual 26
NCT03540043 Terminated Thykamine Safety and Efficacy Study in Mild-to-Moderate Atopic Dermatitis Phase 2 Interventional Reached required analyzable sample size; COVID-19 recruitment challenges Actual 162
NCT04202718 Withdrawn VitalConnect VitalPatch ECG Interpretation/Arrhythmia Detection N/A Interventional Study never started due to COVID-19 pandemic Actual 0
NCT02996448 Terminated Safety, Tolerability, and Immunogenicity of One Dose of NDV 3A Vaccine in People With STAT3-Mutated Hyper-IgE Syndrome Phase 2 Interventional Safety concerns led to early termination. Actual 3
NCT03982537 Withdrawn Effect of N-Acetyl Cysteine (NAC) on the Oral Microbiome Phase 2 Interventional Concept is withdrawn and a different concept will be submitted the near future. Actual 0
NCT04190069 Withdrawn Effects of Behavioral Interventions on Weight Loss and Weight Maintenance N/A Interventional IRB recommended change to registry study or quality improvement project status Actual 0
NCT02352155 Terminated Second-look Endoscopy in High Risk Patients After Endoscopic Hemostasis to Their Bleeding Peptic Ulcers Improves Their Outcomes N/A Interventional Actual 157
NCT02899481 Terminated Role of Intrapartum Ultrasound in Instrumental Delivery N/A Interventional Data Safety Monitoring Committee recommended stopping the trial due to futility. Actual 222
NCT02953119 Terminated Prehabilitation for Elective Major Abdominal Surgery N/A Interventional Difficulty recruiting patients Actual 20
NCT03064152 Terminated Rotational Thromboelastometry for the Transfusion Management of Postpartum Hemorrhage After Vaginal or Cesarean Delivery N/A Interventional slow enrollment, outcome measures collected but actual enrollment is below target enrollment Actual 49
NCT03736421 Suspended Observational Study to Evaluate Peripheral IntraVenous Analysis (PIVA) in Euvolemic, Hypovolemic, and Hypervolemic Emergency Department Patients Observational Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 280
NCT04140591 Terminated Proton Pump Inhibitor Plus Propranolol Versus Proton Pump Inhibitor Alone on Peptic Ulcer Healing in Patients With Liver Cirrhosis Phase 2/Phase 3 Interventional 1. Most patients with liver cirrhosis already use PPI and NSBB 2. 90 % Peptic ulcer size is smaller than 5cm Actual 10
NCT04251182 Suspended Clinical Study Evaluating Efficacy and Safety of T3D-959 in Mild-to-moderate AD Subjects Phase 2 Interventional COVID-19 Panemic Anticipated 256
NCT03136900 Terminated Impact on the Nitrogen Balance, Autonomy, Safety and Tolerance of Enteral Diets Made of With Nutrilon Without Lactose® Fortified by Concentration Versus by Maltodextrin and Oil Supplementation,After Surgery for Congenital Heart Disease, in Infants. N/A Interventional Recuitment to slow Actual 41
NCT02708849 Terminated The Sustained Effects of Ketamine Phase 1 Interventional Actual 3
NCT01803984 Terminated MIBRAIN - Migraine and the Brain: Consequences, Causes, and Vascular Interaction Observational Actual 166
NCT02501473 Terminated Study of Intratumoral G100 With Or Without Pembrolizumab or Rituximab In Patients With Follicular Non-Hodgkin's Lymphoma (MK-3475-174/IMDZ-G142) Phase 1/Phase 2 Interventional Business reasons Actual 52
NCT02702518 Terminated rhDNase Eye Drops in Patients With Ocular Graft-Vs.-Host Disease Phase 1/Phase 2 Interventional The DSMB committee recommended closing the trial because of the COVID-19 risk in this "at-risk" oGVHD population if they came for study visits. Actual 58
NCT03532009 Terminated Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure Phase 2 Interventional Study stopped early due to the COVID-19 pandemic Actual 182
NCT03732196 Terminated Food Frequency Questionnaire for Chinese Pregnant Women Observational Unable to recruit enough participants Actual 68
NCT03925493 Suspended Exercise Prescription in Cardiac Rehabilitation N/A Interventional The COVID-19 pandemic has caused us to suspend recruitment. Anticipated 60
NCT04225078 Suspended A Study to Evaluate the Effects of Loperamide (JNJ-289679) on Electrocardiogram Intervals in Healthy Adult Participants Phase 1 Interventional Trial was put On Hold due to COVID-19. The Site will not start recruiting activities until further notice Anticipated 52
NCT04232878 Terminated A Single Ascending Dose Trial of CVL-936 in Healthy Subjects Phase 1 Interventional Sufficient data has been obtained to meet current objectives Actual 10
NCT04346355 Terminated Efficacy of Early Administration of Tocilizumab in COVID-19 Patients Phase 2 Interventional Based on interim analysis for futility and given an enrolment rate almost nil Actual 126
NCT04363203 Suspended VA Remote and Equitable Access to COVID-19 Healthcare Delivery (VA-REACH TRIAL) Phase 3 Interventional concerns related to study drug Anticipated 300
NCT04416178 Suspended Sickle Cell Disease and the Genomic Needs of Parent and Pediatric Stakeholders Observational Temporary Enrollment Hold due to COVID-19 Anticipated 300
NCT04390386 Withdrawn Controlled Study of IC14 for Treatment of ALS Phase 2 Interventional contract not yet signed Actual 0
NCT01697293 Terminated Triciribine Phosphate, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patients With Stage IIB-IV Breast Cancer Phase 1/Phase 2 Interventional criteria for continuing enrollment in Phase 2 portion was not met Actual 34
NCT02069431 Terminated Oxytocin Aging Study Phase 1 Interventional This study was halted prematurely due to the COVID-19 pandemic, resulting in the inability to enroll participants. Funding for this project has also ended. Actual 153
NCT02070666 Terminated Preventive Strategies in Acute Respiratory Distress Syndrome (ARDS) N/A Interventional Low recruitment and published data with no benefit Actual 98
NCT03051282 Suspended Genetic Determinants of ACEI Prodrug Activation Phase 4 Interventional Enrollment and interactions/interventions are paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 36
NCT03326804 Suspended H1 Hip Resurfacing Arthroplasty Observational awaiting data points for data analysis Anticipated 250
NCT03894579 Withdrawn Autologous Natural Killer Cells in Subjects With Plaque Psoriasis Phase 1 Interventional Study withdrawn per NKMax America Actual 0
NCT03978936 Suspended Medication Adherence With Telehealthcare Medication Therapy Management Phase 3 Interventional Study recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 300
NCT03998514 Suspended A Phase 1a/1b Study of CB4211 in Healthy Non-obese Subjects and Subjects With Nonalcoholic Fatty Liver Disease Phase 1 Interventional COVID-19 related delay Anticipated 86
NCT04240158 Terminated IW-6463 Safety Study in Healthy Elderly Subjects Phase 1 Interventional Some subjects could not complete the second crossover period due to COVID-19-related site closure. The study was closed to allow analysis of all collected data. Actual 24
NCT04362332 Terminated Chloroquine, Hydroxychloroquine or Only Supportive Care in Patients AdmItted With Moderate to Severe COVID-19 Phase 4 Interventional Currently, almost no patients admitted to Dutch hospitals. If any effect of HCQ is to be expected we need more than 1000 inclusions Actual 25
NCT04369742 Suspended Treating COVID-19 With Hydroxychloroquine (TEACH) Phase 2 Interventional Investigator decision Anticipated 626
NCT03790683 Suspended Intraoperative Warming During Major Surgical Procedures Using the Esophageal Temperature Management System N/A Interventional Sponsor funding limitations Anticipated 48
NCT03234153 Terminated Neoadjuvant Immunotherapy With Durvalumab and Tremelimumab for Bladder Cancer Patients Ineligible for Cisplatin Phase 2 Interventional low accrual Actual 6
NCT04361552 Withdrawn Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection) Phase 3 Interventional Study abandoned due to drug billing issues Actual 0
NCT03502954 Terminated A Study to Investigate the Safety, Tolerability and Pharmacokinetics of ABY-039 Phase 1 Interventional Halted prematurely Actual 66
NCT02220790 Suspended BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia Observational [Patient Registry] Final enrollment on hold due to COVID-19 restrictions Anticipated 515
NCT02419105 Terminated Effects of Transdermal Testosterone and/or Monthly Vitamin D on Fall Risk in Pre--frail Hypogonadal Seniors Phase 3 Interventional Delayed recruitment mainly due to a screening to inclusion rate much lower than expected. Due to the delayed recruitment IMP reached the end of its shelf life. Actual 91
NCT02565511 Terminated A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease Phase 2/Phase 3 Interventional Study was terminated by Novartis after a planned review by DMC of unblinded data identified worsening in some measures of cognitive function Actual 480
NCT02733614 Suspended Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD Phase 2 Interventional COVID-19 Anticipated 52
NCT02868827 Terminated Cholecalciferol Supplementation in Critically Ill Patients With Severe Vitamin D Deficiency. Phase 2/Phase 3 Interventional The initial plan was 2 years but due to slow recruitment. We were able to screen 635 patients in 4 years and recruited only 127 patients. Actual 127
NCT03132428 Terminated Registry to Evaluate INOmax in Newborn Babies With Pulmonary Hypertension Observational Positive results at interim analysis Actual 140
NCT03246919 Terminated Ideal Time of Oxytocin Infusion During Cesarean Section Phase 4 Interventional PI left Loyola and Sub-I graduated. Actual 68
NCT03472924 Terminated The Effects of Kinesio Tape® on Arthrogenic Muscle Inhibition and Rate of Torque Development N/A Interventional Insufficient recruitment and enrollment. Reduction in study personnel capacity. Actual 6
NCT03475602 Terminated Membranous Nephropathy-associated Serological Antibody Predict the Prognosis of Idiopathic Membranous Nephropathy Observational [Patient Registry] Our center had adopted a new detection method for anti-PLA2R antibodies in all membranous nephropathy patients. Actual 85
NCT03543033 Withdrawn Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes N/A Interventional The study was closed by the investigators due to lack of study population to enroll. Actual 0
NCT03598036 Terminated Dose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental Glomerulosclerosis Phase 2 Interventional Low recruitment rate Actual 5
NCT03718338 Suspended Mechanisms of Metabolic and Hormone Action on Plaque Formation in Brain and Carotid Vessels in Prostate Adenocarcinoma Observational COVID19 Suspension Anticipated 30
NCT03850509 Terminated Efficacy and Safety of Oral OPS-2071 in Subjects With Crohn's Disease Showing Symptoms of Active Inflammation Phase 2 Interventional Sponsor Decision Actual 3
NCT02193282 Suspended Erlotinib Hydrochloride in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Completely Removed by Surgery (An ALCHEMIST Treatment Trial) Phase 3 Interventional Other - Modifications to MCF Anticipated 450
NCT04175132 Terminated Binding of Foliglurax to Regions in the Brain in Healthy Participants and in Patients With Parkinson's Disease (PD) Phase 1 Interventional New efficacy data from another study Actual 6
NCT04242966 Withdrawn The Effect of Higher Protein Dosing in Critically Ill Patients Ultrasound a Sub-study Phase 3 Interventional Study never started. Operational issues prevented study from rolling out Actual 0
NCT04282798 Withdrawn Racial Variation in Response to Music Interventions for People With Alzheimer's Dementia N/A Interventional COVID delay and subsequent unavailability of staff. Actual 0
NCT03127124 Suspended QUILT-2.022 NANT-008 in Combination w/ 5-fluorouracil, Bevacizumab, Leucovorin & Oxaliplatin in Subjects With Pancreatic Cancer Phase 1/Phase 2 Interventional IRB Recommendation Anticipated 64
NCT03418649 Suspended Eplerenone as a Supplement to Epidural Steroid Injections Phase 4 Interventional Unable to recruit during COVID-19 epidemic restrictions on associated clinical practice Anticipated 40
NCT04436770 Suspended Medical Recovery and Social Reintegration for Post-stroke Patients Using Virtual Reality N/A Interventional Due to the COVID-19 pandemic Actual 52
NCT03906448 Terminated FORWARD Optune and Adjuvant TMZ in Grade II/III Astrocytoma Phase 2 Interventional The study was terminated because the Study Chair/IDE Sponsor and Novocure determined that conducting this trial was not feasible without CMS approval. Actual 2
NCT03957278 Suspended A Study to Evaluate the DAISe System During Neurointervention for Acute Ischemic Stroke N/A Interventional Device modifications Anticipated 120
NCT03987750 Withdrawn Safinamide for Levodopa-induced Dyskinesia (PD-LID) Phase 3 Interventional drug development plan has been updated Actual 0
NCT04329611 Suspended ALBERTA HOPE COVID-19 for the Prevention of Severe COVID19 Disease Phase 3 Interventional Enrolment was suspended on 22may2020, after Mehra et al (Lancet 2020) suggested excess toxicity of HCQ. Anticipated 1660
NCT03707600 Withdrawn State and Trait Mediated Response to TMS in Substance Use Disorder N/A Interventional PI closing his lab Actual 0
NCT04434378 Terminated Tamsulosin to Prevent Postoperative Urinary Retention in Laparoscopic Inguinal Hernia Repair Phase 4 Interventional Significant difference not reached on interim analysis Actual 170
NCT02925988 Terminated Combined Amplitude-integrated and Conventional EEG Monitoring in High-risk Critically Ill Neonates N/A Interventional Actual 4
NCT04434872 Terminated Fecal Microbiota Transplantation as a Treatment for Ulcerative Colitis Phase 2 Interventional Lack of budget Actual 80
NCT00855907 Terminated Fatty Liver in Inflammatory Bowel Disease (IBD) Patients Observational Lack of budget Actual 100
NCT03940287 Terminated Muscle Energy Technique and Kinesiotaping in Mechanical Sacroiliac Joint Dysfunction N/A Interventional Due to COVID-19 lockdown Actual 30
NCT03940339 Terminated Suboccipitalis Myofascial Release in Hamstring Tightness in Patients With Anterolisthesis N/A Interventional Due to COVID-19 lockdown Actual 32
NCT03974009 Terminated Calcaneal Taping on Balance, Gait and Range of Motion in Chronic Stroke Survivors N/A Interventional Due to COVID-19 lockdown Actual 18
NCT04129489 Terminated A Phase 2a Study to Evaluate the Safety and Efficacy of Cannabidiol Only as Maintenance Therapy and Steroid Sparing in Patients With Stable Autoimmune Hepatitis Phase 2 Interventional low recruitment Actual 2
NCT04247308 Suspended Multi Modal Stimulations in Pre-term Neonates N/A Interventional Due to COVID-19 lockdown Anticipated 56
NCT02825043 Terminated HFNC Effect on BCSS in Patients With COPD N/A Interventional Slow enrollment and unable to meet enrollment targets Actual 6
NCT02178566 Terminated Pulmonary Rehab in Chronic Obstructive Pulmonary Disease (COPD): Response to Tyvaso Phase 2 Interventional Unable to enroll Actual 4
NCT03269968 Terminated Use of Negative Pressure Wound Therapy in Morbidly Obese Women After Cesarean Delivery N/A Interventional Recruitment difficulty Actual 25
NCT03738228 Suspended Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer Phase 1 Interventional Scheduled Interim Monitoring Anticipated 40
NCT03774784 Terminated A Study of the Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) Disease Observational The study was terminated due to the impacts of COVID-19 on patient safety and enrollment. Actual 26
NCT04044209 Suspended A Study of the IDH1 Inhibitor AG-120 in Combination With the Checkpoint Blockade Inhibitor, Nivolumab, for Patients With IDH1 Mutated Relapsed/Refractory AML and High Risk MDS Phase 2 Interventional COVID-19 temporary suspension Anticipated 45
NCT04285190 Withdrawn The Effect of T89 on Improving Oxygen Saturation and Clinical Symptoms in Patients With COVID-19 N/A Interventional The COVID-19 pandemic in China has ended completely. As a result, patient recruiting is impossible in China. Actual 0
NCT04285268 Withdrawn Rituximab, Venetoclax, and Bortezomib for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma Phase 2 Interventional funding available Actual 0
NCT04287491 Withdrawn Use Of Virtual Reality For Pain Control in Dermatological Bedside Procedures N/A Interventional Lack of funding Actual 0
NCT04333914 Suspended Prospective Study in Patients With Advanced or Metastatic Cancer and SARS-CoV-2 Infection Phase 2 Interventional Potential recrutment related to the epidemic context. Anticipated 384
NCT04432415 Suspended Comparison of Silver Diamine Fluoride and Sodium Fluoride Varnish to Prevent and Arrest Root Caries in Older Adults N/A Interventional Coronavirus Pandemic Actual 90
NCT03026166 Terminated A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer Phase 1/Phase 2 Interventional Enrollment was stopped after the dose-limiting toxicity (DLT) evaluation phase of Cohort 2. Actual 42
NCT02997228 Suspended Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer, the COMMIT Study Phase 3 Interventional Other - Study requires an approved DTL template Anticipated 200
NCT01003769 Terminated Lenalidomide and AT-101 in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia Phase 1/Phase 2 Interventional Lack of funding Actual 5
NCT02119312 Suspended Malaria Clinical Trials Center General Screening Observational [Patient Registry] COVID19 safety measures-institutional policy to suspend non-covid related studies Anticipated 3500
NCT02521870 Terminated A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Phase 1/Phase 2 Interventional A strategic restructuring including the planned conclusion of clinical oncology development programs and no further sponsoring of the development of SD-101. Actual 241
NCT02764086 Terminated INTENSE: A Phase I/II Study of INhomogeneous Targeted Dose Escalation in Non-Small CEll Lung Cancer Phase 1/Phase 2 Interventional Accrual lower than anticipated and not expected to improve Actual 6
NCT03731117 Suspended FURosemide Stress Test to Predict Need of Renal Replacement THERapy in Ischemic Acute Tubular Necrosis in ICU Phase 4 Interventional Study with inclusions suspended due to COVID-19 since 18th march 2020 Anticipated 70
NCT04284462 Terminated Liking Adaptation to Beverages of Varying Sweetness Levels After Prolonged Exposure N/A Interventional Sponsor decision to stop study due to COVID-19 pandemic Actual 170
NCT04431232 Suspended Endo-Band: Endoscopic Band Ligation for Weight Loss N/A Interventional Due to COVID-19 pandemic Anticipated 5
NCT02357004 Withdrawn Mechanisms of Refractory Hypertension (Carvedilol) N/A Interventional Actual 0
NCT02357017 Withdrawn Mechanisms of Refractory Hypertension (High and Low Salt Diet) N/A Interventional Actual 0
NCT03403751 Terminated Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury Phase 3 Interventional Very slow enrollment of target patient population Actual 58
NCT03489512 Withdrawn Comparison Trial for Chloraprep Versus Aqueous Chlorhexidine (2%) for the Prevention of Catheter-related Bacteremia Phase 4 Interventional Administrative issues Actual 0
NCT03053050 Terminated Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis Phase 3 Interventional This study was terminated early due to lack of efficacy based on the results of the Week 48 analysis as prespecified in the clinical study protocol. Actual 808
NCT04106700 Suspended Prophylaxis With Apixaban in Transplant Eligible Patients With Multiple Myeloma Receiving Induction Therapy With IMiDs Phase 2 Interventional Low recruitment Anticipated 60
NCT04428762 Withdrawn Glycemic Control and Quality of Life With i- Port Advance in Pediatric T1DM N/A Interventional we decided to change the protocol completely to an RCT. Actual 0
NCT00230308 Suspended Identification and Characterization of Novel Proteins and Genes in Head and Neck Cancer Observational Suspended due to Covid-19 Anticipated 500
NCT02568917 Suspended Effectiveness of ART and Conventional Treatment - Practice-based Clinical Trial N/A Interventional There was a problem with the municipality and they have choose to suspend it. Anticipated 800
NCT03054636 Terminated Short-term Perfusion Angiography Pilot Study (SPA) Observational After data review of enrolled pts, it was determined that initial study objectives would not be met w/ continuation of enrollment Actual 38
NCT03292536 Terminated Merestinib on Bone Metastases in Subjects With Breast Cancer Phase 1 Interventional Enrollment incomplete by the end of the contracted enrollment period Actual 2
NCT03724253 Terminated [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR) Phase 2 Interventional Recruitment was stopped before the target sample size was achieved. Actual 19
NCT03745196 Terminated The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases Phase 2 Interventional The study is being terminated early as a result of the coronavirus (COVID-19) outbreak. Actual 13
NCT03785730 Suspended Ultraconservative Caries Treatment in Anterior Cavitated Caries Lesion of Primary Teeth N/A Interventional Outbreak of COVID-19. Anticipated 196
NCT03785769 Suspended Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement N/A Interventional The Outbreak of COVID-19. Anticipated 192
NCT03827889 Suspended Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth N/A Interventional Outbreak of COVID-19. Anticipated 168
NCT03870841 Terminated The Effect of PC945 on Aspergillus Fumigatus Lung Infection in Patients With Cystic Fibrosis Phase 2 Interventional The study is being terminated early as a result of the coronavirus (COVID-19) outbreak. Actual 4
NCT03905447 Terminated The Effect of Early Treatment of PC945 on Aspergillus Fumigatus Lung Infection in Lung Transplant Patients. Phase 2 Interventional The study is being terminated early as a result of the coronavirus (COVID-19) outbreak. Actual 2
NCT03908944 Withdrawn Postoperative Pain and Headache After Craniotomy Phase 2 Interventional PI- Dr. Jellish passed away. The study was terminated with the IRB Actual 0
NCT03966300 Suspended Improving the School Vaccination Experience: What CARDs Are You Going to Play? N/A Interventional Study suspended because of Covid-19 - no vaccinations are occurring in schools Anticipated 1400
NCT03966391 Suspended Effectiveness of CARD for Improving School-Based Immunizations N/A Interventional Study suspended because of Covid-19 - there are no vaccinations in schools Anticipated 7800
NCT04344379 Suspended Prevention of SARS-CoV-2 in Hospital Workers s Exposed to the Virus Phase 3 Interventional suspension of clinical trials with hydroxychloroquine by health authorities Actual 122
NCT04393597 Withdrawn Effects of Food on the Pharmacokinetics of DWJ1458 in Healthy Adults Phase 1 Interventional We decided to discontinue this particular clinical study through internal discussion. Actual 0
NCT02212730 Terminated A Study Evaluating the Effect of Pembrolizumab (MK-3475) in Participants With Renal Cell Cancer (MK-3475-031) Phase 1 Interventional Terminated early due to low enrollment Actual 10
NCT02328287 Terminated Study on Allogeneic Osteoblastic Cells Implantation in Rescue Interbody Fusion Phase 2 Interventional Actual 6
NCT02501265 Suspended Adaptive Pharmacotherapy for Smoking Cessation Phase 2 Interventional Enrollment suspended due to COVID-19 Anticipated 188
NCT02665988 Terminated Adjunctive Transcranial Direct Current Stimulation N/A Interventional We terminated the study because the Pain Management Program closed in January 2018. Actual 4
NCT03079102 Terminated Inhaled Nitric Oxide After Out-of-Hospital Cardiac Arrest Phase 2 Interventional Slow enrollment and planned change of institution by PI Actual 57
NCT03186937 Suspended A Window of Opportunity Study of Methionine Deprivation in Triple Negative Breast Cancer Phase 2 Interventional due to COVID-19 Anticipated 25
NCT03277222 Terminated Intranasal Treatment of HIV-associated Neurocognitive Disorders Phase 2 Interventional Unable to find further eligible participants Actual 4
NCT03318757 Withdrawn Bupivacaine Liposomal Injectable Suspension, Pain and Narcotic Use After Elective Orthognathic Surgery Phase 4 Interventional The research could not be conducted as it was denied by the IRB. Actual 0
NCT03819686 Suspended Reducing Disparities in Living Donor Transplant Among African Americans N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 850
NCT03914079 Suspended Evaluation of the CAD-det System, a Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease Observational [Patient Registry] Sponsor due to COVID-19 Anticipated 2000
NCT03988582 Withdrawn Safety and Effectiveness of EBV-specific Cytotoxic T Cells for the Treatment for EBV Lymphomas or Other EBV-associated Malignancies Phase 2 Interventional Lack of accrual Actual 0
NCT03995966 Suspended A Clinical Trial for Self-Injurious Behavior N/A Interventional Paused due to COVID-19 and expected to resume; Not a suspension of IRB approval. Anticipated 30
NCT04149444 Withdrawn A Study of Trifluridine/Tipiracil in Triple Negative Metastatic Breast Cancer Phase 2 Interventional Sponsor withdrew support Actual 0
NCT04257214 Suspended Therapy and Peer Support for Patients Taking Medication for Opioid Use Disorder N/A Interventional COVID-19 Anticipated 440
NCT04428242 Withdrawn Study Evaluating Retinal Health Monitoring System Thickness Module Observational COVD-19 Actual 0
NCT01926301 Withdrawn Cerebrovascular Autoregulation in Sepsis, Influence of Renal Replacement Therapy Observational Actual 0
NCT01978509 Terminated The Affect of Low-Volume Bowel Preparation for Hospitalized Patients Colonoscopies N/A Interventional Lack of enrollment Actual 32
NCT02173470 Terminated Chest CT With Iterative Reconstruction as an Alternative to Conventional Chest X-ray Prior to Heart Surgery N/A Interventional Expected futility in reaching the primary endpoint Actual 866
NCT02317302 Terminated FDG Tumor Heterogeneity During Chemoradiation as a Predictor of Response in Patients With Cervical Cancer Phase 1 Interventional Insufficient funding Actual 48
NCT02462200 Terminated Shave Margins in Breast Conservation Therapy Phase 2 Interventional Insufficient funding Actual 81
NCT02542241 Terminated Hypertonic Saline Resuscitation in Trauma Patients After Hemorrhage Control Phase 4 Interventional lack of funds to continue recruitment Actual 52
NCT02887248 Terminated Nab-paclitaxel Plus Gemcitabine as First-line Therapy for Cisplatin-ineligible or Cisplatin-incurable Advanced Urothelial Carcinoma Phase 2 Interventional Enrollment issues Actual 3
NCT03138083 Terminated OMO-1 in Solid Malignancies Phase 1/Phase 2 Interventional strategic reasons (not due to lack of efficacy or safety issues) Actual 40
NCT03300609 Terminated 5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab Phase 3 Interventional Insufficient Accrual Actual 4
NCT03726905 Suspended Complex Exercises of the Respiratory Muscles Plus Aerobic Training vs. Aerobic Training in Patients With СHF N/A Interventional Study suspended because of COVID 19 Anticipated 60
NCT03856580 Suspended Long-acting Biomedical HIV Prevention in Transgender Women N/A Interventional Due to COVID-19 pandemic Anticipated 45
NCT03864328 Terminated A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF Phase 2 Interventional COVID-19 Pandemic Actual 108
NCT03929068 Suspended Sinemet for Spasticity and Function in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis Phase 1 Interventional COVID-19 Pandemic Anticipated 15
NCT04090879 Suspended Low Nicotine Content Cigarettes in Vulnerable Populations: Affective Disorders Phase 2 Interventional COVID19 pandemic Anticipated 232
NCT04092101 Suspended Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder Phase 2 Interventional COVID19 pandemic Anticipated 310
NCT04092387 Suspended Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age Phase 2 Interventional COVID19 pandemic Anticipated 246
NCT04345861 Terminated Hydroxychloroquine Plus Azithromycin Versus Hydroxychloroquine for COVID-19 Pneumonia (COVIDOC Trial) Phase 2/Phase 3 Interventional halted prematurely. Actual 7
NCT01850108 Suspended Non-Myeloablative Conditioning and Bone Marrow Transplantation N/A Interventional COVID-19 response Anticipated 25
NCT03794024 Terminated Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome Observational Manufacturer of the device filed for bankruptcy Actual 3
NCT04424576 Suspended Ovarian Morphology in Girls Observational Suspended due to COVID-19. No suspension of IRB approval. Anticipated 60
NCT01973881 Suspended Quantitative MRI for Myelofibrosis Observational Enrollment paused due to COVID-19 and will resume in the future. This is not a suspension of IRB approval. Anticipated 120
NCT03023449 Suspended Diffuse Optical Monitoring With Inhaled Nitric Oxide Phase 2 Interventional Enrollment in this study has been temporarily suspended due to the COVID-19 pandemic. Anticipated 40
NCT03161964 Terminated Propranolol in Treating Hypoglycemia Unawareness Phase 2 Interventional Statistical power could not be achieved due to low enrollment. Actual 2
NCT03224546 Suspended Cocaine Use Reduction and Health N/A Interventional COVID-19 Anticipated 250
NCT03445767 Withdrawn Structured Polypharmacy Management Before Elective Non-cardiac Surgery in Frail and Elderly People N/A Interventional Did not receive full funding to proceed Actual 0
NCT03496077 Suspended Addictive Potential of LCCs in Dual Users N/A Interventional COVID outbreak Anticipated 125
NCT03786783 Suspended Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant Phase 2 Interventional Other - Pending evaluation of patients on study currently Anticipated 45
NCT03877198 Terminated Comparison of Oxygen Controllers in Preterm InfanTs N/A Interventional As a result of a slower inclusion rate than expected, competence of medical staff to work with the AVEA ventilator could no longer be guaranteed. Actual 15
NCT03895853 Terminated Early Metabolic Resuscitation for Septic Shock Phase 2 Interventional At the request of the PI Actual 2
NCT03937986 Suspended Suvorexant and Cocaine Early Phase 1 Interventional COVID-19 Anticipated 20
NCT03954938 Suspended Behavioral Effects of Drugs (Inpatient): 38 Early Phase 1 Interventional COVID-19 Anticipated 30
NCT03960606 Suspended Study in Adult Asthmatic Patients With Allergic Bronchopulmonary Aspergillosis Phase 2 Interventional COVID-19 Pandemic Anticipated 64
NCT04203511 Withdrawn INCMGA00012 in Combination With Chemoradiation in Participants With Stage III Non-Small Cell Lung Cancer (POD1UM-301) Phase 3 Interventional Sponsor Strategic/Business Decision Actual 0
NCT04420247 Suspended Efficacy of Chloroquine or Hydroxychloroquine in Treating Pneumonia Caused by SARS-Cov-2 - COVID-19 Phase 3 Interventional WHO has recommended Chloroquine studies to be suspended for lack of efficacy. Actual 54
NCT00001219 Terminated Comparing Magnetic Resonance Imaging/Spectroscopy Techniques Observational protocol has not been used for many years and has outlived it utility Actual 49946
NCT03243058 Suspended Low-dose IL-2 in Established T1D - The "PROREG" Study Phase 1/Phase 2 Interventional Funding withdrawal and COVID-19 environment. Anticipated 60
NCT03343613 Terminated A Study of LY3381916 Alone or in Combination With LY3300054 in Participants With Solid Tumors Phase 1 Interventional Study terminated due to strategic business decision by Eli Lilly and Company. Actual 60
NCT02506114 Terminated Neoadjuvant PROSTVAC-VF With or Without Ipilimumab for Prostate Cancer Phase 2 Interventional Low Accrual Actual 15
NCT02812407 Withdrawn HRIM vs Mucosal Impedance in GERD Participants N/A Interventional No linger a clinically relevant research question Actual 0
NCT03349840 Terminated Randomised Open Label Study of Insulin Degludec Versus Insulin Glargine U100 in Ramadan Phase 4 Interventional The study was terminated by the IRB and the Institutional Official after the MOPH and WCMQ audits Actual 273
NCT03613259 Withdrawn Fluorothymidine F-18 PET in Diagnosing Patients With Intermediate or High Grade Soft Tissue Sarcoma Early Phase 1 Interventional Funding expired Actual 0
NCT03810183 Terminated A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia Phase 2 Interventional Company decision Actual 9
NCT03916146 Suspended Behavioral Parent Training for Families With Deaf and Hard of Hearing Preschoolers N/A Interventional Research activity paused for COVID-19 Anticipated 300
NCT03944551 Terminated Bubble Continuous Positive Airway Pressure for Children With Severe Pneumonia in Mali, Africa N/A Interventional Participant mortality rates were higher than expected. Actual 13
NCT04186689 Suspended Relationship Between Food Insecurity and Child Dental Anxiety Observational COVID -19 pandemic Anticipated 300
NCT04419792 Suspended 'A Profile of Physical Performance Variables in an Out-patient Adult Population With Narcolepsy' Observational Recruitment for study has been suspended due to Covid-19. Anticipated 70
NCT00985907 Terminated Doxil® + Melphalan + Velcade (DMV) in Relapsed/Refractory Multiple Myeloma Phase 1/Phase 2 Interventional Low Accrual Actual 13
NCT00393224 Terminated Defining the Clinical Utility of EBV Antibody Screening to Identify Individuals Susceptible to Nasopharyngeal Carcinoma (NPC) Within High-Risk, Multiplex NPC Families Observational Determined not to be human subject reseach Actual 952
NCT01257100 Terminated Environmental and Genetic Determinants of NPC Observational Determined not to be Human Subject Research Actual 3500
NCT02512237 Terminated A Dose-escalation Study of ARX788, IV Administered in Subjects With Advanced Cancers With HER2 Expression Phase 1 Interventional Replace with a new trial Actual 9
NCT02767934 Terminated Pembrolizumab in Treating Minimal Residual Disease in Patients With Acute Lymphoblastic Leukemia Phase 2 Interventional Terminated due to lack of efficacy Actual 12
NCT02974673 Terminated Pilot Study of Ejaculatory Dyssynergia by Electronic Microsensors of Sphincters N/A Interventional lack of recruitment Actual 11
NCT03301636 Terminated A Study of Indoximod or Placebo Plus Pembrolizumab or Nivolumab for Subjects With Unresectable or Metastatic Melanoma Phase 2 Interventional Sponsor termination, not related to efficacy, safety or feasibility. Actual 21
NCT03448133 Withdrawn rTMS for the Treatment of Primary Progressive Aphasia: A Randomized Controlled Trial N/A Interventional Because of the expiration of the previous ethical approval documents Actual 0
NCT03537547 Terminated Combinatorial Pharmacogenomics Testing in Treatment-Naïve Major Depressive Disorder Phase 4 Interventional Per sponsor and PI institution discussions Actual 6
NCT03571646 Terminated LIFEGUARD Study - Continuous Respiratory Monitoring on the General Ward N/A Interventional Poor recruitment rate due to difficulties in identifying suitable patients Actual 6
NCT03579758 Withdrawn Chemotherapy Before & After Surgery in Patients With Resectable Gallbladder Cancer Phase 3 Interventional This trial will open as an NCTN trial. Actual 0
NCT03735160 Withdrawn Pressure Over Nasotracheal Intubation Related Nasal Alar Injury Observational Technical problem Actual 0
NCT03822689 Withdrawn Comparison of Ventilation Tubes Among Anesthetized Pediatrics N/A Interventional Institutional Review Board did not approve Actual 0
NCT03869372 Suspended Cerebral Cortical Influences on Autonomic Function N/A Interventional Covid-19 Anticipated 96
NCT03918499 Suspended IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer Phase 1/Phase 2 Interventional Temporary on hold Anticipated 20
NCT03952143 Suspended A Study of LY900014 Compared to Insulin Lispro (Humalog) in Adults With Type 2 Diabetes Phase 3 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 564
NCT04084665 Withdrawn Biomarkers in Participants With Hidradenitis Suppurativa Receiving Guselkumab. Early Phase 1 Interventional COVID-19 Pandemic Actual 0
NCT04097431 Suspended Identifying Precursors to Severe Problem Behavior N/A Interventional Temporarily paused due to COVID-19 and expected to resume; not a suspension of IRB approval. Anticipated 60
NCT04118036 Suspended Abemaciclib + Pembrolizumab In Glioblastoma Phase 2 Interventional Safety concerns Anticipated 47
NCT04144127 Suspended Prostate Cancer Soccer N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 40
NCT01870869 Terminated NATRELLE® 410 X-Style and L-Style Breast Implants Continued Access Study N/A Interventional There was no indication that long-term follow-up would differ between any of the studies that have evaluated devices within the 410 Style Matrix. Actual 1951
NCT02083939 Terminated Prophylactic Antibiotic Treatment for Laparoscopic Inguinal Hernia Mesh Repair: Necessary or Not? Observational Recruitment failed Actual 5
NCT03284476 Withdrawn Post Surgically Treated Peritonitis Complications Observational No inclusion Actual 0
NCT03284489 Withdrawn Post Pancreatitis Complications Study (Based on a Prospective Data Base) Observational No inclusion Actual 0
NCT03407287 Suspended Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status Observational interim analysis Anticipated 180
NCT03744598 Terminated Self-monitoring of Spirometry & Symptoms Via patientMpower App in Idiopathic Pulmonary Fibrosis Observational Clinic visits stopped due to COVID19 Actual 21
NCT03862690 Withdrawn A Research Study, Looking at How NovoMix® Works in People With Type 2 Diabetes in Local Clinical Practice in Algeria Observational Sponsor decision Actual 0
NCT03867240 Suspended Gabapentin and Chronic Post Surgical Pain Phase 3 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 100
NCT04001231 Withdrawn Study of Exenatide Once-Weekly Suspension in Chinese Patients With Type 2 Diabetes Mellitus Phase 1 Interventional The study is stopped based upon strategic considerations impacting the clinical development of exenatide once-weekly suspension in China Actual 0
NCT04417816 Terminated Ultrasound-induced Adipose Tissue Cavitation and Training in Obesity N/A Interventional At the request of the Ethical Committee Actual 28
NCT04140877 Withdrawn Choroidal Changes Post Short Term Exposure To Virtual Reality Devices N/A Interventional Strategy change Actual 0
NCT04239534 Suspended CONVERGE CAP Study-For The Treatment Of Symptomatic Persistent or Long-standing Persistent AF N/A Interventional Start-up and enrolling activities have been temporatily suspended due to the COVID-19 pandemic. Anticipated 170
NCT04333654 Suspended Hydroxychloroquine in Outpatient Adults With COVID-19 Phase 1 Interventional Sponsor decision pending further evaluation of information related to benefit-risk Anticipated 210
NCT04347512 Withdrawn EVALUATION OF THE EFFICACY OF THE HYDROXYCHLOROQUINE-AZITHROMYCIN COMBINATION IN THE IN THE PREVENTION OF COVID-19 RELATED SDRA Phase 3 Interventional In view of the notices concerning hydroxychloroquine issued by the regulatory authorities, we withdraw the protocol Actual 0
NCT01210027 Suspended A Study of Radiation Toxicity in the Liver Using MRI-Based Perfusion Observational Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 140
NCT02045381 Suspended Optimization of MRI for Radiation Therapy Observational Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 432
NCT02250924 Withdrawn Caffeinated Gum to Prevent Post-Operative Ileus: A Prospective, Randomized, Placebo-controlled Trial N/A Interventional Investigator decision - clinical practice change Actual 0
NCT02303392 Suspended Selinexor and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Aggressive Non-Hodgkin Lymphoma Phase 1 Interventional pending amendment Anticipated 92
NCT02748746 Withdrawn Early Detection of Lymphedema With Bio-Electrical Impedance Analysis in Patients After Breast Cancer Surgery N/A Interventional Unable to achieve device(s) which will be used in this study. Actual 0
NCT03115320 Terminated Frozen-thawed Embryo Transfer in a Naturally Stimulated Cycle: Does hCG Triggering Bring Any Advantage in Comparison to Testing LH Surge With Home Tests? Phase 4 Interventional High cancellation rate in LH test group in interim analysis Actual 62
NCT03287063 Suspended Study Using Genomic, Histologic and Radiomic Analysis to Evaluate Regional Tumor Heterogeneity in Patients Undergoing Surgery for Newly Diagnosed Glioblastoma Observational Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 20
NCT03325114 Terminated Safety and Efficacy of Chlorthalidone in Type 1 Diabetes Phase 2 Interventional COVID restrictions prohibit further study activies Actual 1
NCT03941717 Suspended Testing the Effectiveness of a Parent and Child Mindfulness-Based Intervention for Child Venipuncture N/A Interventional COVID-19 restrictions Anticipated 150
NCT03970109 Suspended HLAB-002 of ANS-6637 for Alcohol Use Disorder Phase 2 Interventional Clinical Hold for Safety Anticipated 81
NCT04086342 Withdrawn CHI-902 for Treatment of Social Anxiety Disorder Phase 2 Interventional Changes in pipeline Actual 0
NCT04100629 Terminated Digital Support Intervention on Newly Licensed Nurses N/A Interventional Lack of enrollment (and due to pandemic) Actual 23
NCT04139980 Suspended Virtual Reality Device for Rehabilitation of Stroke Patients N/A Interventional staffing resources Anticipated 100
NCT04189315 Withdrawn Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease Phase 4 Interventional R&D portfolio review and in light of the global impact of the COVID-19 pandemic Actual 0
NCT04332081 Terminated Hyperbaric Oxygen for COVID-19 Patients N/A Interventional The IRB has determined that the design of this trial should be changed to a randomized controlled trial. A new record will be created for the redesigned study. Actual 20
NCT04341727 Suspended Hydroxychloroquine,Hydroxychloroquine,Azithromycin in the Treatment of SARS CoV-2 Infection Phase 3 Interventional DSMB recommended study suspension slow accrual Anticipated 500
NCT04371926 Withdrawn Prophylactic Benefit of Hydroxychloroquine in COVID-19 Cases With Mild to Moderate Symptoms and in Healthcare Workers With High Exposure Risk N/A Interventional Concerned about the adverse effects of HCQ Actual 0
NCT03536338 Terminated Spinal Stimulation Sit-to-Stand Training After Spinal Cord Injury N/A Interventional COVID-19 pandemic Actual 9
NCT04003519 Withdrawn Study to Predict Lanreotide-induced Disease Activity Normalization in Acromegaly Observational Study timeline delay, low site feasibility and delay concerns due to COVID-19. Actual 0
NCT03933930 Withdrawn Comparing the Prognosis of Lactate-directed and Goal-directed Therapy in Hyperthermic Intraperitoneal Chemotherapy. N/A Interventional No patient wants to be recruited. Actual 0
NCT04411121 Suspended Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-risk Head and Neck Cancer Phase 2/Phase 3 Interventional Scheduled Interim Monitoring Anticipated 613
NCT02842125 Terminated Safety and Efficacy of Intra-Arterial and Intra-Tumoral Ad-p53 With Capecitabine (Xeloda) or Anti-PD-1 in Liver Metastases of Solid Tumors and Recurrent Head and Neck Squamous Cell Cancer Phase 1/Phase 2 Interventional Arm C rolled into parallel study; Arms A and B halted for greater efficacy in Arm C Actual 4
NCT03610763 Suspended Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 347
NCT03637023 Suspended Virtual Reality for Parkinson's Disease N/A Interventional due to COVID-19 outbreak Anticipated 30
NCT04032158 Terminated Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis (RMS) Phase 3 Interventional Administrative reason by Sponsor. Actual 3
NCT02125331 Terminated Measurement of NonInvasive Blood Pressure in Neonates Through Adults and Special Populations Observational Data collection requirment complete Actual 83
NCT04164069 Suspended Dasatinib in Preventing Oxaliplatin-Induced Peripheral Neuropathy in Patients With Colorectal Cancer Receiving FOLFOX and Bevacizumab Phase 1 Interventional PI Decision Anticipated 20
NCT04184518 Withdrawn Durvalumab (MEDI4736) Plus Cediranib in Patients With Metastatic Uveal Melanoma Phase 2 Interventional The Cediranib producer laboratory decided to stop the development of this product. Actual 0
NCT04235270 Suspended A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants Phase 1 Interventional Occurrence of COVID-19 pandemic Anticipated 62
NCT04300413 Suspended Patient-Centered, Interprofessional Approach to Improve Functional Outcomes in a Skilled Nursing Facility N/A Interventional On hold due to COVID-19 outbreak Anticipated 53
NCT03010137 Terminated Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial N/A Interventional Lack of staff resources to properly consent and enroll patients into the study. Actual 30
NCT00001651 Terminated Use of Labeled Glucose to Study Lymphocyte Replication and Survival in HIV-Infected Patients N/A Interventional Slow/Insufficient accrual Actual 54
NCT02353000 Terminated Whole Brain Radiotherapy (WBRT) Versus Stereotactic Radiosurgery (SRS) for 4 Upto 10 Brain Metastases N/A Interventional Unable to achieve accrural within anticipated timeframe Actual 31
NCT02625376 Terminated Resveratrol for Exudative Age-Related Macular Degeneration N/A Interventional Actual 25
NCT03256331 Terminated Evaluate the Safety of BEL-X-HG in Advanced Cancer Patients Phase 1 Interventional In the light of the on-going COVID-19 pandemic and the resulted difficulty in patient recruitment. Actual 23
NCT03393806 Terminated Repeat Dose Study of GSK3772847 in Participants With Moderate to Severe Asthma With Allergic Fungal Airway Disease (AFAD) Phase 2 Interventional Recruitment was terminated early before meeting target enrolment due to a high screen failure rate and the feasibility of completing the study in a timely way Actual 18
NCT02281877 Suspended Alterations in Muscle After Total Knee Arthroplasty N/A Interventional On hold due to COVID-19 outbreak Anticipated 20
NCT02898753 Terminated VAL-1221 Delivered Intravenously in Ambulatory and Ventilator-free Participants With Late-Onset Pompe Disease Phase 1/Phase 2 Interventional Company closure due to lack of funding Actual 12
NCT03054961 Suspended Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study Observational Protocol Amendment in process, pending reengineering of intruments Anticipated 40
NCT03274817 Terminated A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol Phase 1 Interventional Insufficient Enrollment Actual 5
NCT03410056 Terminated Safety and Efficacy of AMG 592 in Subjects With Active Rheumatoid Arthritis Phase 1/Phase 2 Interventional Amgen made a business decision not to proceed with Phase 2. Actual 36
NCT04415372 Suspended Macromolecular Imaging of White and Gray Matter Pathology in Multiple Sclerosis Observational Suspended due to COVID-19 Anticipated 50
NCT03629249 Terminated Systemic Corticosteroids Avoidance Study in Severe Asthma Patients Phase 3 Interventional Company decision Actual 609
NCT03713099 Withdrawn NEUWAVE Flexible Probe Study #2 N/A Interventional Changed study design prior to any patients enrolled. Actual 0
NCT04017637 Withdrawn Resistance Training Intervention to Promote Lean Mass in Youth With IBD N/A Interventional Study cancelled Actual 0
NCT04002882 Suspended Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF) Observational Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 90
NCT04116229 Suspended Cognition and Magnetic Resonance Imaging of Brain Inflammation in Obesity Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 20
NCT02872935 Terminated Minimizing Nausea and Vomiting During Spinals for CS Phase 4 Interventional Actual 22
NCT00933829 Terminated Comparison of Cosmetic Outcomes of Lacerations Repaired Using Absorbable Versus Non-absorbable Sutures N/A Interventional Actual 160
NCT01126853 Withdrawn Combination Hepatitis A and B Vaccine to Induce Immunity in Non-responders Phase 4 Interventional Actual 0
NCT02765516 Terminated Genetic Basis for Prediction of Non-responders to Dietary Plant Sterol Intervention N/A Interventional Inability to recruit Actual 43
NCT03165968 Suspended Test and Evaluation of Non-Invasive Neuro-Assessment Devices (NINAD): NeuroKinetics, Inc, iPAS Observational COVID19 epidemic, and institutional guidelines for halt of recruitment during epidemic Anticipated 150
NCT03357042 Withdrawn Evaluation of a Physical Intervention for Persistent Post-Concussive Symptoms N/A Interventional researchers did not find participants to meet the inclusion and exclusion criteria for the testing protocols Actual 0
NCT03790865 Terminated Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome Phase 2/Phase 3 Interventional Livoletide did not result in a statistically significant improvement in hyperphagia and food-related behaviors Actual 158
NCT03953521 Terminated Neuronavigated TBS in Depression N/A Interventional Interim analysis indicated no statistical difference between treatment arms. Actual 37
NCT04032171 Terminated Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis Phase 3 Interventional Administrative reason by Sponsor. Actual 1
NCT04092257 Suspended HPV-Based Screen-and-Treat Demonstration Project in Lilongwe N/A Interventional The study was about to start recruiting but in response to COVID-19, screening and enrollment has been put on hold. Anticipated 625
NCT04114630 Withdrawn Study of Quality of Life in Subjects With Chronic or High-frequency Episodic Migraine and Associated Comorbidities Treated With Erenumab Phase 3 Interventional No patients were enrolled and global prioritization of pipeline and research strategy Actual 0
NCT02766478 Suspended Genistein Supplementation to Mitigate Cardiometabolic Dysfunction in Patients Undergoing Androgen Deprivation Therapy for Prostate Cancer Phase 2 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 24
NCT04174794 Terminated Investigating Reduction of aCute heArt Failure Readmission With Lung UltraSound-preliminary Trial Observational COVID-19 Pandemic Actual 43
NCT02813668 Suspended Worksite Lifestyle Program for Reducing Diabetes and Cardiovascular Risk in India N/A Interventional Study activities involving participants are suspended due to COVID-19 Actual 2065
NCT04198844 Withdrawn The Effectiveness and Safety of Apixaban in NVAF Patients With History of Osteoporosis and/or Fracture: A Nation-wide Population Based Study Observational Interaction term analysis result was not significant and thus comparative effectiveness for primary and secondary outcomes could not be considered per protocol. Actual 0
NCT04205890 Withdrawn Intravenous Ketamine Effects on Functional Neuroanatomy Phase 1 Interventional Sponsor is no longer interested in funding the study Actual 0
NCT04332549 Withdrawn To Assess the Bioavailability and Safety of Paclitaxel Injection Concentrate for Suspension in Subjects With Locally Recurrent or Metastatic Breast Cancer Phase 1 Interventional After meeting with the FDA, SPARC concludes a BE study will not be required Actual 0
NCT04334967 Suspended Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care Phase 4 Interventional suspected unfavorable risk/benefit assessment Actual 13
NCT03307057 Suspended Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families N/A Interventional The study activities are on hold due to COVID Anticipated 250
NCT02946437 Withdrawn Sevoflurane in Subarachnoidal Haemorrhage Phase 2 Interventional Patients failed to be enrolled because of tight exclusion criteria. Actual 0
NCT03595748 Suspended Peer Mentorship to Improve Outcomes in Patients on Maintenance Hemodialysis N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval Anticipated 200
NCT04413487 Withdrawn Early Detection of Heart Problems in Cancer Patients Receiving Chemotherapy Observational Study never started due to change in standard of care guideline Actual 0
NCT03999190 Withdrawn Imaging Dopamine D2 Agonist Binding Sites in Schizophrenia Observational investigational radiotracer was not approved Actual 0
NCT04003935 Terminated Juice Plus Inflammaging and Cardiovascular Disease Prevention Study Observational One of the 2 nutritional products is reformulated and withdrawn from the market Actual 22
NCT04041596 Withdrawn Degree of Benefit From Low-Frequency Acoustic Amplification Using the Advanced Bionics Acoustic Earhook Phase 4 Interventional Due to a lack of enrollment Actual 0
NCT04162431 Suspended DOLPHIN-VIVO: Diagnosis Of LymPHoma IN Vivo (Ex Vivo Phase) Observational Covid19 Anticipated 250
NCT04213014 Suspended Guys/Girls Opt for Activities for Life Trial (GOAL) to Increase Young Adolescents' Physical Activity and Healthy Eating Phase 3 Interventional Recruitment halted due to COVID19 Anticipated 1760
NCT04289883 Withdrawn Food Structure and Satiety N/A Interventional The Covid-19 pandemic that made it impossible to conduct within the timeframe. Actual 0
NCT04407832 Withdrawn Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy N/A Interventional Actual 0
NCT03235986 Terminated A Study To InvestigateThe Safety, Tolerability And Efficacy Of Nebulised Curosurf® In Preterm Neonates With Respiratory Distress Syndrome (RDS) Phase 2 Interventional Change in the benefit-risk balance Actual 166
NCT03654755 Terminated Study to Evaluate Long-Term Safety of ASN002 in Subjects With Moderate to Severe Atopic Dermatitis Phase 2 Interventional Phase 2 study results Actual 168
NCT03728504 Terminated Study to Evaluate ASN002 in Subjects With Moderate To Severe Chronic Hand Eczema Phase 2 Interventional Primary Endpoint completed and continuing visit schedule complications due to COVID-19 Actual 19
NCT03770299 Withdrawn An Investigational Immuno-therapy Study of Nivolumab Given After Surgery in Non-Small Cell Lung Cancer (NSCLC) Participants With Minimal Residual Disease Phase 2 Interventional Business objectives have changed Actual 0
NCT02281344 Terminated MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants Phase 1 Interventional Inconsistent and unpredictable exposures were observed. Drug needed to be reformulated. Actual 6
NCT02667327 Terminated A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer Phase 3 Interventional Sponsor Decision (No safety or efficacy concerns) Actual 124
NCT02744612 Suspended Ibrutinib and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma Phase 2 Interventional Anticipated 39
NCT02860078 Suspended Epidural Injection of Corticosteroids Under USG (EICUS) N/A Interventional Not started Anticipated 30
NCT02924389 Suspended Dolutegravir in Reservoirs N/A Interventional Enrollment and study visits are temporarily suspended due to COVID-19. Anticipated 40
NCT02975128 Terminated Minimal Invasive Breast Cancer Excision Using the Breast Lesion Excision System Under Ultrasound Guidance N/A Interventional Needle production stopped Actual 22
NCT03318107 Terminated Ultrasound and Photoacoustic Imaging for Cervical Cancer N/A Interventional Low accrual Actual 2
NCT03335020 Withdrawn Using Ultrasonography, Shear Wave Elastography, Strain Imaging, and 3-D Volume Ultrasonography on Cardiovascular Disease Phase 1 Interventional Closed by Investigator Actual 0
NCT03342911 Suspended Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery Phase 2 Interventional COVID-19 Anticipated 37
NCT03418532 Terminated MP0250 DARPin® Protein Plus Osimertinib in Patients With EGFR-mutated NSCLC Phase 1/Phase 2 Interventional Sponsor's decision Actual 8
NCT03457025 Withdrawn Effect of Adjuvant Hyperbaric Oxygen Therapy on Bells Palsy Outcome Early Phase 1 Interventional lack of enrollment Actual 0
NCT03492138 Terminated Ixazomib, ONC201, and Dexamethasone in Relapsed/Refractory Multiple Myeloma Phase 1/Phase 2 Interventional Low enrollment Actual 5
NCT03551119 Suspended Physical Activity in Renal Disease (PAIRED): The Effect on Hypertension Phase 3 Interventional Covid-19 pandemic Anticipated 160
NCT03648216 Suspended The Effect of Experimentally Increasing Sedentary Behaviour on Subjective Well-being N/A Interventional Recruitment and study progress halted by COVID-19 Anticipated 46
NCT03968835 Withdrawn A Comparison of the Outcomes of Distal Fingertip Amputations Treated With Either Artificial (Xeroform) or Biological Dressings Observational lack of enrollment Actual 0
NCT03970356 Suspended Improving Antibiotic Prescribing for Urinary Tract Infections in Frail Elderly N/A Interventional Study paused due to Covid-19 outbreak Anticipated 680
NCT02149823 Suspended Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations Phase 1 Interventional COVID-19 Anticipated 165
NCT02532517 Terminated Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device N/A Interventional No safety issues; change in innovation strategy Anticipated 320
NCT02694341 Withdrawn Bakri Balloon in Placenta Previa N/A Interventional No participants shared Actual 0
NCT02866279 Suspended Immediate Postpartum Contraceptive Implant Placement and Breastfeeding Success in Women at Risk for Low Milk Supply: A Non-inferiority Trial N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 375
NCT02923986 Withdrawn Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDS Phase 1/Phase 2 Interventional No enrollment Actual 0
NCT03036319 Suspended Patient-Centered NeuroRehabilitation (PCN) N/A Interventional Enrollment and interactions/interventions are temporarily paused due to COVID-19 and are expected to resume in the future. Anticipated 500
NCT03451851 Suspended A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants Phase 3 Interventional Enrollment Hold due to COVID-19 Anticipated 125
NCT03341000 Terminated Pilot Study to Examine the Feasibility of the Dynamic Interferential Spinal Cord Stimulation System™ (DISCSS™) N/A Interventional Sponsor Decision Actual 18
NCT03395119 Suspended Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects Phase 1 Interventional Suspended due to COVID-19 risks Anticipated 60
NCT03517995 Withdrawn Randomized, Phase II Clinical Trial of Sulforaphane in Bladder Cancer Chemoprevention Phase 2 Interventional Grant not approved Actual 0
NCT03520309 Suspended Clinical Criteria for the Evaluation of Caries Lesions Around Restorations in Primary Teeth (CARDEC-03) N/A Interventional Follow-ups paused temporarily since March 16th due to COVID-19 Actual 163
NCT04016116 Withdrawn Dual PD-1 and JAK2 Inhibition in Hematological Malignancies Phase 2 Interventional PI left the institution Actual 0
NCT03630367 Suspended Effects of L‑Carnitine Supplementation on Respiratory Distress Syndrome Phase 4 Interventional Unavailability of the medication Anticipated 300
NCT03717532 Terminated Blood Flow Restriction Therapy in Patellofemoral Pain Syndrome N/A Interventional Inadequate/low enrollment Actual 1
NCT03729310 Withdrawn Comparison of Two Steroid Nasal Implants Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis Early Phase 1 Interventional No participants enrolled Actual 0
NCT04404348 Suspended Cognitive Rehabilitation for Opioid Abuse-related Cognitive Impairment N/A Interventional Study halted due to Covid-19 precautions Anticipated 50
NCT04056637 Terminated Choice of Modality of Follow up for Medication Abortion N/A Interventional COVID-19 Impacted Service Delivery and Research Infrastructure Actual 26
NCT04074304 Suspended Developing and Piloting a Multi-component Technology-based Care Intervention to Address Patient Symptoms and Caregiver Burden in Home Hospice. Phase 1. N/A Interventional Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval Anticipated 30
NCT04123197 Suspended Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis N/A Interventional The study activities are suspended due to COVID Anticipated 300
NCT02515669 Terminated Study of an Investigational Drug, RO7239361 (BMS-986089), in Ambulatory Boys With DMD Phase 1/Phase 2 Interventional A pre-planned futility analysis indicated lack of efficacy. Actual 43
NCT04179721 Suspended Reducing Behavioral and Psychological Symptoms of Dementia N/A Interventional COVID-19; study will resume when restrictions are lifted. Anticipated 158
NCT04230720 Suspended Effect of Artificial Tears on Biometry Phase 4 Interventional Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 30
NCT04404790 Suspended Antiplatelet Thrombolysin (Anfibatide) Phase 1 Clinical Trial in Healthy Volunteers Phase 1 Interventional Optimization of protocol Anticipated 50
NCT04409314 Suspended Hypoxia-Specific Imaging to Predict Outcomes of Chimeric Antigen Receptor T-cell Therapy Observational Drug Supply Anticipated 30
NCT01263652 Withdrawn Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine Patients N/A Interventional inability to complete recruitment as planned Actual 0
NCT03132064 Suspended The Association Between Pre-operative Pain Psychology and Hypersensitivity With Poor Functional Outcome After Knee Replacement. Observational COVID-19 Anticipated 50
NCT03611296 Suspended Translational Investigation of Growth and Everyday Routines in Kids (TIGER Kids) Fitness Ancillary Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Actual 30
NCT04341610 Withdrawn ASC Therapy for Patients With Severe Respiratory COVID-19 Phase 1/Phase 2 Interventional Not approved by ethical committee Actual 0
NCT02430649 Withdrawn Irreversible Electroporation(IRE) For Unresectable Prostatic Neoplasms N/A Interventional Actual 0
NCT03699644 Suspended Multimodal Ocular Imaging in Neurodegeneration N/A Interventional Enrollment/interactions/interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 50
NCT04402775 Terminated Brachiocephalic Arteriovenous Fistulae: Two Different Techniques of Bloodless Surgery and Their Effect on Fistula Stenosis. N/A Interventional Due to a low inclusion rate Actual 25
NCT04406610 Terminated CAR-T Cell Immunotherapy for GD2 Positive Glioma Patients Phase 1/Phase 2 Interventional Actual 2
NCT02557529 Terminated Progressive Resistance Training in Head and Neck Cancer Patients During Concomitant Chemoradiotherapy N/A Interventional Slow recruition Actual 50
NCT02897713 Suspended Feasibility, Safety, and Outcomes of Intensive Enteral Nutrition in Patients With Mechanical Ventilation N/A Interventional Similar study has been published. Anticipated 400
NCT04128436 Terminated The Effect of Luteal Blood Progesterone Levels on Ongoing Pregnancy Rates N/A Interventional With the interim analysis, a marked decrease in ongoing pregnancy rate was noted in patients with a drop in serum progesterone level from OPU+3 day to OPU+5 day Actual 126
NCT04402294 Suspended Individualized Closed Loop TMS for Working Memory Enhancement N/A Interventional COVID-19 Restrictions Anticipated 38
NCT03495427 Suspended PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores Phase 2/Phase 3 Interventional Compounding facility to submit quality update before they can manufacture 18F-DCFPyL Anticipated 60
NCT02545283 Terminated A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) Phase 3 Interventional The study was stopped for futility based on efficacy results at the interim analysis; no unexpected safety findings were observed. Actual 447
NCT03551717 Terminated Retinal Microvascularization and Cardiovascular Disease Observational Lack of inclusion Actual 155
NCT03575507 Withdrawn Non-invasive Improvement of Buttocks With Magnetic Device N/A Interventional It wasn't possible to recruit the desired number of patients. Actual 0
NCT03812341 Withdrawn SINGLE PATIENT EXPANDED ACCESS OF A PROSPECTIVE, MULTICENTER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND PROBABLE BENEFIT OF THE KERAKLEAR NON-PENETRATING KERATOPROSTHESIS IN SUBJECTS WITH CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT N/A Interventional No enrollment Actual 0
NCT03946774 Suspended Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 20
NCT04069260 Terminated A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis Phase 2 Interventional Due to study design limitations, this study has been discontinued and will not proceed with the 2nd cohort as contemplated in the original protocol. Actual 3
NCT04141046 Suspended LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE N/A Interventional Suspended due to COVID-19 risks Anticipated 72
NCT04207905 Suspended Evaluation of the Healthy Michigan Plan Section 1115 Community Engagement Requirement Waiver Observational On 3/4/20 a federal judge ruled the HMP work requirement unlawful, thereby ending it and suspending implementation of this RCT. This is not an IRB suspension. Anticipated 229000
NCT04306861 Suspended Novel MRI Techniques for Pancreatic Cancer Observational Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 20
NCT04350450 Withdrawn Hydroxychloroquine Treatment of Healthcare Workers With COVID19 Illness at Montefiore Phase 2 Interventional PI withdrew the submission to the IRB Actual 0
NCT04377737 Withdrawn Incidence of Covid-19 in School Children N/A Interventional Human Subjects Protection Review: submitted, denied Actual 0
NCT01805973 Terminated Surviving Aneurysm Surgery: A Pilot Study on Exercise Training in Abdominal Aortic Aneurysm Patients N/A Interventional Anticipated 100
NCT02636387 Terminated Desmopressin as a Therapy for Bedwetting in Children With Sickle Cell Disease Observational Low recruitment Actual 14
NCT02816437 Withdrawn FMT for MDRO Colonization in Solid Organ Transplant Phase 1 Interventional safety Actual 0
NCT03115151 Suspended Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery Phase 4 Interventional COVID-19 policy Anticipated 58
NCT03348280 Suspended Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics Observational temporarily paused due to Covid-19 and expected to to resume, this is not a suspension of IRB approval. Anticipated 40
NCT03438435 Suspended Fluorescence QRH-882260 Peptide Imaging in the Bile Duct Phase 1 Interventional Enrollment and interactions/interventions temporarily paused due to COVID-19 & may resume in the future. No suspension of IRB approval. Anticipated 12
NCT03453658 Suspended Mechanized Instrumentation for Endodontic Treatment of Primary Teeth N/A Interventional Follow-ups paused temporarily since March 16th, 2020 due to COVID-19. Anticipated 150
NCT03579147 Withdrawn Non-invasive Buttock Lifting Induced by Magnetic Device - Multicentric Study N/A Interventional It was not possible to recruit any patients at that time. Actual 0
NCT03610347 Terminated Paclitaxel Eluting Balloon After Bare Metal Stent Implantation vs. Drug-Eluting Stent in St Elevation Myocardial Infarction N/A Interventional Low recruitment Actual 199
NCT03844750 Suspended Pembrolizumab After Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and Who Are Undergoing Liver Surgery Phase 2 Interventional Pending Amendment Anticipated 19
NCT03852576 Suspended Phase 1B Study of KSP/QRH Dimer for Detection of Neoplasia in the Esophagus Phase 1 Interventional Enrollment and interactions/interventions temporarily paused due to COVID-19 & will resume in the future. No suspension of IRB approval. Anticipated 50
NCT03856125 Withdrawn Percutaneous Electrical Stimulation on Radial Nerve in Patients With Lateral Epicondylalgia N/A Interventional Covid19 locked down Actual 0
NCT03896477 Suspended Phase 3 Study of 10-valent Pneumococcal Conjugate Vaccine (PNEUMOSIL) Administered in a 2+1 Schedule to Healthy Infants Phase 3 Interventional Temporarily halted some in-person research activities due to COVID-19 pandemic Actual 660
NCT04044391 Terminated Use of Magnetocardiography in Evaluation of Patients Going for Cardiac Catheterization Observational Study was defunded. Actual 101
NCT04114656 Suspended Effects of Intravenous GSK3858279 on a Battery of Evoked Pain Tests in Healthy Volunteers Phase 1 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 24
NCT04175600 Suspended A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension Phase 3 Interventional Due to COVID-19 pandemic, a decision was made on 01Apr2020 to temporarily suspend further screening Anticipated 237
NCT04009850 Suspended Impact of Cigarette and E-cigarette Flavors on Adult Smoking Behavior N/A Interventional Temporarily suspended due to COVID-19 pandemic. Anticipated 50
NCT04117607 Terminated Safety and Pharmacokinetics of Rezafungin Phase 1 Interventional Stopped due to the formation of injection site skin nodules. Actual 14
NCT04241159 Withdrawn Study to Explore the Safety and Feasibility of Allogeneic Young Plasma Infusion in Older Adults Early Phase 1 Interventional Protocol required revisions and application was withdrawn from the IRB. Actual 0
NCT02608229 Terminated BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer Phase 1 Interventional Adverse events Actual 18
NCT04399291 Suspended Vitamin D Status and Bone Health of Older Adults in Care Facilities Observational COVID-19, study status being reviewed on an ongoing basis. Anticipated 200
NCT02940457 Withdrawn Cognitive Ability Training for Seniors With Mild Cognitive Impairment N/A Interventional The employe for the study quit and a new grant proposal was not financed Actual 0
NCT03779802 Terminated Prospective Multicentric Study Comparing the Acute Hemodynamic Effect of Three Modes of Stimulation in Cardiac Resynchronization Therapy Recipients N/A Interventional With the current health situation, we do not anticipate a significant resumption of recruitment for several months. Actual 50
NCT04010448 Suspended A Trial to Assess the Safety, Immunogenicity and Efficacy of a Trivalent Rotavirus P2-VP8 Subunit Vaccine in Prevention of Severe Rotavirus Gastroenteritis in Healthy Infants in Africa and India Phase 3 Interventional temporarily halted due to COVID-19 Anticipated 8200
NCT04248335 Suspended Effect of Obesity on Proton Pump Inhibitors Phase 4 Interventional Suspended due to COVID-19; No suspension of IRB approval Anticipated 150
NCT04307693 Terminated Comparison of Lopinavir/Ritonavir or Hydroxychloroquine in Patients With Mild Coronavirus Disease (COVID-19) Phase 2 Interventional Terminated early because no patients were further enrolled since mid-Apr 2020. Actual 65
NCT03354637 Terminated A Study of ATI-50002 Topical Solution for the Treatment of Alopecia Areata Phase 2 Interventional The double-blind primary endpoint was not met. Open Label Extension period halted as a result. Actual 129
NCT02931110 Suspended Study of IV CBL0137 in Previously Treated Hematological Subjects Phase 1 Interventional Business reasons Anticipated 230
NCT03137199 Terminated Allogeneic Human Cells (hMSC) Via Intravenous Delivery in Patients With Mild Asthma Phase 1 Interventional First cohort completed. Per sponsor decision. Actual 3
NCT03479905 Suspended The Use of High Flow Nasal Cannula, Standard Face Mask and Standard Nasal Cannula in Morbidly Obese Patients N/A Interventional COVID-19 policy Anticipated 216
NCT03716466 Suspended Evaluation of Prophylactic Endotracheal Intubation Observational Suspended due to covid-19 policy Anticipated 100
NCT04020042 Suspended Epidural Placement Using Handheld Ultrasound Device vs. Traditional Landmark Palpation N/A Interventional COVID-19 policy Anticipated 300
NCT04247009 Suspended Postprandial Inflammation in Rheumatoid Arthritis N/A Interventional Due to risk for covid-19 spreading, the study was suspended 12 march 2020. Anticipated 80
NCT04328350 Suspended Social Experiences of Adolescents and Young Adults With Cancer Observational Required COVID-19 related change Anticipated 200
NCT04354714 Withdrawn Ruxolitinib to Combat COVID-19 Phase 2 Interventional Could not make FDA required changes Actual 0
NCT03624192 Terminated RES Prepared With RECELL® Compared to Conventional Care for Healing of Donor Sites in Ages 1-16 Years N/A Interventional Study closed in response to COVID-19 and overall program objectives. Actual 3
NCT04093648 Withdrawn T Cells co- Expressing a Second Generation Glypican 3-specific Chimeric Antigen Receptor With Cytokines Interleukin-21 and 15 as Immunotherapy for Patients With Liver Cancer (TEGAR) Phase 1 Interventional The key elements of this study were incorporated into another study. Actual 0
NCT02830438 Terminated Shear Wave Elastography in Native Kidney Disease N/A Interventional Not enough participants recruited Actual 8
NCT00601939 Suspended Effectiveness of Empowerment Group Sessions for Treating Suicidal African American Women in Abusive Relationships N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 397
NCT01490827 Terminated Argus® II Retinal Prosthesis System Post-Market Surveillance Study Observational Sponsor discontinued the Argus II product Actual 52
NCT01574664 Withdrawn Evaluation of RFID Localization System for Marking and Retrieving Breast Lesions Observational Not required to be registered Actual 0
NCT01627301 Suspended Sympathetic Overactivity in Post-traumatic Stress Disorder N/A Interventional The study activities are suspended due to COVID-19 Anticipated 100
NCT01947673 Suspended Mechanisms of Intradialytic Hypertension N/A Interventional Study activities are suspended due to COVID-19 Anticipated 100
NCT02204904 Terminated Observational Study to Evaluate Allogeneic HSCT Outcomes for Cerebral Adrenoleukodystrophy (CALD) Observational Sufficient enrollment for Month 24 safety and efficacy endpoints Actual 59
NCT02411773 Suspended Sympatholysis in Chronic Kidney Disease Phase 2 Interventional Study activities are temporarily suspended due to COVID-19. Anticipated 110
NCT02562092 Suspended The Georgia Latino AIDS/HIV Diagnosis and Linkage in Youth (GLADLY) Project N/A Interventional Enrollment and study visits are temporarily suspended due to COVID-19. Anticipated 112
NCT02624258 Terminated Pilot Study of Non-Viral, RNA-Redirected Autologous T Cells in Patients With Refractory or Relapsed Hodgkin Lymphoma Early Phase 1 Interventional Principal Investigator decision to stop trial Actual 2
NCT02641509 Terminated Accuracy in Resection of Non-pedunculated Colonic Lesions 5-20 mm With/Without Using NBI N/A Interventional Actual 113
NCT02818959 Terminated First in Man Study of the JenaValve TAVI Plus System Transfemoral N/A Interventional Due to inability to recruit sufficient sample size in reasonable time frame. Actual 7
NCT02947750 Suspended Neurovascular Transduction During Exercise in Chronic Kidney Disease Phase 2 Interventional Study activities are temporarily suspended due to COVID-19. Anticipated 150
NCT03074695 Suspended DPE Technique in Labor Epidural for Morbidly Obese Women Phase 4 Interventional COVID 19 Pandemic Anticipated 130
NCT03265249 Suspended BRIDGE Device for Post-operative Pain Control N/A Interventional COVID-19 Restrictions Anticipated 50
NCT03565406 Terminated A Phase 1b Study of the Selective HDAC Inhibitor Mocetinostat in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma Phase 1 Interventional recruiting or enrolling participants has halted prematurely and will not resume; participants are no longer being examined or treated Actual 11
NCT03677284 Suspended Managing Time With Dementia: Effects of Time Assistive Products in People With Dementia N/A Interventional Due to the situation of virus Covid-19, recruitment is paused from 7th April. Anticipated 74
NCT03783650 Suspended Boosting Primary Care Awareness and Treatment of Childhood Hypertension N/A Interventional Temporarily paused due to COVID-19 and expected to resume. Anticipated 64
NCT03805438 Suspended ED90 of 3% Chloroprocaine for Cervical Cerclage Phase 4 Interventional COVID 19 Pandemic Anticipated 40
NCT03890419 Suspended Opioid Sparing Potential of Light-Induced Analgesia N/A Interventional COVID-19 restrictions Anticipated 90
NCT04040751 Suspended Carepartner Collaborative Integrated Therapy in Sub-Acute Stroke N/A Interventional Enrollment is suspended due to COVID-19, prescreening continues for future enrollment. Anticipated 36
NCT04068272 Suspended Safety of Bosentan in Type II Diabetic Patients Phase 1 Interventional Covid 19 general restrictions in Spain - Will eventually be resumed Anticipated 22
NCT04072367 Withdrawn FIrst-Pass Reperfusion With the NeVa Stent-Retriever Trial N/A Interventional The study was withdrawn due to a change in company strategy. Actual 0
NCT00900575 Suspended Cervical Cancer Detection Using Optical Spectroscopy N/A Interventional COVID-19 Anticipated 350
NCT02469129 Suspended PET Imaging of PARP Activity in Cancer Early Phase 1 Interventional Suspended due to COVID19 Anticipated 50
NCT02604277 Suspended Suicidal Behavior in Patients Diagnosed With Bipolar Disorder N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 130
NCT02720185 Suspended Window of Opportunity Trial of Dasatinib in Operable Triple Negative Breast Cancers With nEGFR Phase 2 Interventional Recruitment suspended due to COVID-19 Anticipated 19
NCT02788214 Terminated Helicobacter Pylori Genome Project Observational research determined not to be human subject research Actual 821
NCT03078192 Suspended Non-Invasive Diagnosis of Pulmonary Vascular Disease Using Inhaled 129Xe Magnetic Resonance Imaging Phase 2 Interventional suspended for this protocol due to the pandemic Anticipated 127
NCT03138564 Suspended An Effectiveness-Implementation Trial of SPIRIT in ESRD N/A Interventional Enrollment is temporarily suspended due to COVID-19. Anticipated 800
NCT03206125 Terminated NCI UNC Project ESCC Observational determined not to be human subjects research Actual 648
NCT03342157 Terminated Docusate/Senna for the Treatment of Diabetic Gastroparesis Phase 2 Interventional low enrollment Actual 2
NCT03342235 Withdrawn Excimer Laser Surgery for Anisometropic Amblyopia N/A Interventional Study not started due to lack of recruitment potential. Actual 0
NCT03367312 Suspended Assessing Response to Inhaled Prostacyclin With Hyperpolarized Xe MRI Phase 2 Interventional suspended for this protocol due to the pandemic, Anticipated 12
NCT03415022 Suspended Computer-Based Treatment for Social Anxiety Disorder N/A Interventional Due to COVID19 Pandemic Anticipated 40
NCT03506620 Withdrawn The Role of Nerve Blocks in Hip Arthroscopy Phase 4 Interventional Unforeseen cost restrictions of the drug halted the execution of this study altogether. Actual 0
NCT03533465 Suspended Understanding the Role of Sleep in Complicated Grief N/A Interventional Due to funding limitations Anticipated 10
NCT03574792 Suspended Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy N/A Interventional Temporarily Suspended due to COVID-19 Anticipated 60
NCT03631680 Suspended The Role of Estrogen in Adipocyte Remodeling Following Surgical Menopause Observational Temporarily paused due to COVID-19 and expected to resume. Anticipated 10
NCT03650881 Withdrawn The Comparative Efficacy of an Over the Counter Light Therapy Mask vs Over the Counter Topical Benzoyl Peroxide 2.5% and Used in Combination With Over the Counter Adapalene Gel 0.1% for Mild to Moderate Acne N/A Interventional no eligible subjects were enrolled Actual 0
NCT03651869 Suspended Effects of Nicotine in Tobacco Smokers Phase 1 Interventional Study recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 220
NCT03686813 Suspended Sildenafil for Swimming-Induced Pulmonary Edema (SIPE) Prevention Phase 2 Interventional Due to COVID-19 pandemic research stoppage Anticipated 20
NCT03742817 Suspended Effects of e-Cigarettes on Perceptions and Behavior N/A Interventional Study recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 40
NCT03751358 Terminated ESP Volunteer LA Spread Controlled by MRI N/A Interventional Problem with MRI interpretation Actual 8
NCT03781388 Suspended ED90 for Hyperbaric Bupivacaine in Super Obese Parturients Phase 4 Interventional COVID 19 Pandemic Anticipated 40
NCT03856268 Suspended Understanding the Roles of Hormones in Adipocyte Remodeling Following Menopause Observational Temporarily paused due to COVID-19 and expected to resume. Anticipated 12
NCT03933956 Suspended Metabolic Effects of the SGLT-2 Inhibitor Empagliflozin in Patients With Diabetic Nephropathy (MEDiaN) Phase 3 Interventional The study will be temporarily suspended due to the COVID-19 situation. Anticipated 40
NCT03966144 Withdrawn RoboHear™ Device: Advanced Haptic Technology That Allows the Deaf to Understand Speech N/A Interventional Company discontinued study and closed. No participants were enrolled. Actual 0
NCT04013880 Suspended ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia Phase 1/Phase 2 Interventional Paused for COVID 19 Response Anticipated 80
NCT04053452 Suspended Peripheral Nerve Ultrasound for Diagnosis and Prognosis of Guillain-Barre Syndrome N/A Interventional Due to COVID-19 restrictions Anticipated 50
NCT04107181 Suspended Pilot Study for Speculum Free Cervical Cancer Screening N/A Interventional COVID-19 Anticipated 305
NCT04333498 Suspended Use of Antiretroviral (ARV) Drug Levels in Dried Blood Spots (DBS) to Assess and Manage ART Adherence in South Africa N/A Interventional Due to COVID19 Pandemic Anticipated 60
NCT04399031 Suspended Effects of e-Cigarettes on Perceptions and Behavior - Substudy 1 N/A Interventional Study recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 200
NCT04395638 Suspended Replenishing and Maintaining Vitamin D Status in Older Adults in Residential Care Facilities in NI N/A Interventional COVID-19 study status being reviewed on an ongoing basis. Anticipated 40
NCT03588806 Terminated Use of Xtampza ER to Overcome Difficulties in Swallowing Opioid Pills Phase 4 Interventional Study halted permanently and will not resume; participants are no longer being examined or receiving intervention. Actual 11
NCT02687165 Terminated Uncovering Neural and Immune Mechanisms of Chronic Pain in Post Treatment Lyme Syndrome N/A Interventional Slow recruitment due to strict inclusion/exclusion criteria Actual 4
NCT01796470 Terminated Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic Malignancies Phase 2 Interventional Study was terminated due to safety measures. Actual 66
NCT03610048 Terminated A Long Term Study of ALKS 5461 in the Treatment of Refractory Major Depressive Disorder (MDD) Phase 3 Interventional Sponsor Decision Actual 175
NCT04066790 Terminated Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer Phase 2 Interventional We terminated this trial and initiated a new one including pertuzumab. Actual 12
NCT04249596 Suspended Tianeptine for Treatment Resistant Depression Phase 4 Interventional Due to COVID-19 Pandemic Anticipated 75
NCT04396834 Terminated Mechanisms of Lorcaserin for Smoking Cessation Phase 2 Interventional Medication removed from the U.S. market by the The Food and Drug Administration Actual 3
NCT04396847 Terminated Laboratory Screening of Lorcaserin for Alcohol Use Disorder Phase 2 Interventional Medication removed from the U.S. market by the The Food and Drug Administration Actual 5
NCT00903266 Suspended Melodic-Intonation-Therapy and Speech-Repetition-Therapy for Patients With Non-fluent Aphasia Phase 3 Interventional Covid-19 Pandemie Anticipated 30
NCT02201355 Suspended Hypofractionated Reduced-Volume Chemoradiation for T1/2N0-2 SCC Head and Neck Phase 1 Interventional PI LEFT THE DEPARTMENT Anticipated 60
NCT03104335 Withdrawn Apatinib for Advanced Soft Tissue Sarcoma Patients: a Phase 2, Multicenter Trial Phase 2 Interventional Not enough patients Actual 0
NCT03150420 Terminated A Phase 3 Clinical Trial of Intravenous Sodium Thiosulfate in Acute Calciphylaxis Patients Phase 3 Interventional Inability to accrue subjects that met the exclusion criterion "Any prior (within the past 30 days) or current Sodium Thiosulfate treatment". Actual 29
NCT03342300 Withdrawn Pegylated Liposomal Doxorubicin Versus Pirarubicin Plus Ifosfamide, Dacarbazine in Locally Advanced, Unresectable or Metastatic Soft-tissue Sarcoma Phase 2/Phase 3 Interventional No participants enrolled Actual 0
NCT03440008 Suspended Improving the Detection, Classification and Treatment of Misaligned Arthritic Ankles Observational ORD hold on non-treatment participant visits re: COVID19 Anticipated 110
NCT03476642 Suspended Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks Phase 4 Interventional Temporarily suspended due to Pandemic. Anticipated 24
NCT03655119 Suspended PES Family Support and Follow-Up Program N/A Interventional Enrollment and interventions are temporarily paused due to COVID-19 and are expected to resume in the future.This is not a suspension of IRB approval. Actual 229
NCT03694197 Terminated Long Term Safety Study of PRALUENT Phase 4 Interventional The primary objective (to evaluate the long-term safety of Praluent) was adequately evaluated in other studies. Actual 1389
NCT03694548 Suspended Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 20
NCT03788070 Terminated Prevalence of Preoperative Dehydration in Major Elective Urologic Surgery and Its Impact on Postoperative Outcome Observational Due to COVID-19 study inclusion was halted on March 16, 2020 after 309 days. Actual 188
NCT03805711 Terminated HLT Meridian Valve CE Mark Trial N/A Interventional Sponsor decision to stop enrollment. Actual 1
NCT03814382 Terminated Acupuncture to Reduce Anxiety in Alzheimer's Disease (AD) and AD Related Dementias N/A Interventional Termination of study funding Actual 9
NCT04044378 Withdrawn Famitinib Plus Camrelizumab & Famitinib Alone & Famitinib Plus Ifosfamide in Advanced Osteosarcoma Phase 1/Phase 2 Interventional toxicity Actual 0
NCT04139694 Withdrawn Improving Insulin Resistance in Gynecological Cancer Patients N/A Interventional unable to procure supplement for clinical trial use Actual 0
NCT04393831 Suspended A Prospective Trial on Nerve Sparing Techniques Performed in Radical Prostatectomy N/A Interventional Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 112
NCT04394312 Suspended Parent PLAYSHOP: A Physical Literacy Training Workshop for Parents N/A Interventional COVID-19 physical distancing protocols and closures Anticipated 100
NCT04394832 Terminated Reducing Intrusive Memories in Refugees and Asylum Seekers With PTSD: A Pilot Study N/A Interventional Covid-19 Actual 4
NCT04277624 Suspended A Study to Assess Bioequivalence of Fezolinetant Formulations in Healthy Postmenopausal Female Participants Phase 1 Interventional Due to COVID-19. Anticipated 22
NCT01880073 Terminated FemVue and Tubal Patency N/A Interventional Slow recruitment Actual 24
NCT04394962 Suspended Virtual Reality Use in Assisted Reproductive Technology N/A Interventional Due to COVID-19 situation Anticipated 350
NCT00181220 Withdrawn Valproic Acid in the Induction of EBV Lytic Cycle Antigen Expression in Nasopharyngeal Carcinoma Phase 1 Interventional PI left JHU and is not able to be reached for updates Actual 0
NCT00358241 Withdrawn Effects of Nerve Block on Knee Function After Knee Replacement N/A Interventional PI left JHU and is not able to be reached for updates Actual 0
NCT00367718 Withdrawn Trial of VELCADE in Patients With Metastatic or Locally Recurrent Nasopharyngeal Carcinoma Phase 2 Interventional PI left JHU and is not able to be reached for updates Actual 0
NCT01493258 Withdrawn Comprehensive Informatics Framework for Comparative Effectiveness Research (CER) Dissemination N/A Interventional PI left JHU and is not able to be reached for updates Actual 0
NCT02015650 Terminated Cetuximab Compared to Mitomycin-C and 5-Fluorouracil for Locally Advanced Squamous Cell Carcinomas of the Head and Neck Phase 4 Interventional Low Recruitment rate Actual 4
NCT02232568 Terminated Trial of Feedback on Blood Use N/A Interventional Insufficient numbers of participating sites and hip surgery cases. Actual 426
NCT02536170 Suspended Arginine Therapy for Sickle Cell Disease Pain Phase 2 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 114
NCT02657356 Terminated Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST Phase 3 Interventional Exposure of these high-risk patients to clinic or in-person visits during the pandemic presented an unacceptable risk to their health Actual 202
NCT02658916 Terminated Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003 Phase 1 Interventional 251PP301(NCT03068468) primary endpoint was not met;further development of Gosuranemab BIIB092 in progressive supranuclear palsy will not be pursued. Actual 47
NCT02993354 Suspended Noninvasive Monitoring of Uterine Electrical Activity and Fetal Heart Rate: A New External Monitoring Device Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 55
NCT03054038 Suspended Afatinib and Necitumumab in Patients With EGFR Mutation Positive Advanced or Metastatic Non-small Cell Lung Cancer Phase 1 Interventional Pause for COVID-19 Response Anticipated 60
NCT03154827 Terminated A Phase Ib/II, Multicenter, Single Arm, Open-Label Study, To Evaluate the Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab Combination for Maintenance Treatment in Subjects With Acute Myeloid Leukemia Who Are 60 Years or Older - The BATTLE Study Phase 1/Phase 2 Interventional Due to lack of enrollment Actual 1
NCT03394664 Suspended FB4 (Framingham, Boston, Bloomington, Birmingham, and Baylor) N/A Interventional In light of COVID-19, the FB4 trial is indefinitely on hold. Anticipated 125
NCT03662074 Suspended Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer Phase 2 Interventional Interim analysis per protocol Anticipated 29
NCT03706872 Terminated Efficacy of an App for Monitoring Physical Activity and Weight of Obese Pregnant Women (Pas&Pes) N/A Interventional Women`s confinement for COVID-19 pandemic and changes on prenatal care. Actual 123
NCT04093349 Suspended A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE) Phase 1/Phase 2 Interventional Due to the COVID-19 pandemic, enrollment has been suspended until further notice Anticipated 20
NCT04099056 Suspended Brain Stimulation and Decision-making N/A Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 100
NCT04116606 Suspended Antidepressant Trial With P2X7 Antagonist JNJ-54175446 Phase 2 Interventional Due to currect Covid-19 pandemic. Anticipated 142
NCT04208698 Terminated A Scintigraphy Study in Adults With Diabetic Gastroparesis Phase 2 Interventional Trial was terminated due to the impact of COVID-19 on trial activities. Actual 2
NCT04261582 Suspended Genetics and Genomics of Aspirin Exacerbated Respiratory Disease (AERD) Observational On hold due to COVID-19 outbreak Anticipated 245
NCT04264637 Suspended Study to Find Out How Long it Takes Azelastine Hydrochloride 0.15% Nasal Spray to Relieve Symptoms in Patients Suffering From Allergic Rhinitis Phase 3 Interventional Covid-19 pandemic Anticipated 80
NCT03309033 Terminated Fifteen-year Immunologic Follow-up of Women Who Received One, Two and Three Doses of the Bivalent HPV Vaccine in the Costa Rica HPV-16/18 Vaccine Trial (CVT): Generating Durability Data: The ESCUDDO-CVT Study Observational NIH is not engaged in human subjects research Actual 869
NCT03204539 Terminated INdividualized ITI Based on Fviii(ATE) Protection by VWF Phase 4 Interventional Termination of funding from sponsor. Actual 1
NCT03781609 Suspended Motor Learning Approach for Manual Wheelchair Users N/A Interventional Temporarily paused due to COVID-19, expected to resume, IRB not suspended. Anticipated 48
NCT03941600 Suspended Feasibility of Exercise and Spinal Cord Injury N/A Interventional Temporarily paused due to COVID-19, expected to resume, IRB not suspended. Anticipated 40
NCT03957057 Suspended Intravenous Iron Carboxymaltose, Isomaltoside and Oral Iron Sulphate for Postpartum Anemia Phase 3 Interventional Covid-19 Anticipated 300
NCT04077879 Suspended Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP1617 in Healthy Adult Non-Asian and Japanese Subjects Including Assessment of a Food Effect Phase 1 Interventional Due to COVID-19 Anticipated 97
NCT04184895 Suspended A Study to Assess the Safety, Tolerability and Immunological Response of ASP2390 in Adult Subjects Allergic to House Dust Mites Phase 1 Interventional Due to COVID-19 Anticipated 28
NCT02479906 Terminated A Safety & Efficacy Study With Deep Transcranial Magnetic Stimulation for the Treatment of Post-Traumatic Stress Disorder (PTSD) N/A Interventional The results did not demonstrate sufficient clinical benefit induced specifically by the active treatment to justify continuation of the trial. Actual 203
NCT03032042 Withdrawn Intestinal Microbiome Post-Azythromycin/Albendazole Treatment Phase 4 Interventional We were not able to secure IRB approval in the timeline necessary to do this study. Actual 0
NCT03040024 Terminated Delirium Prevention With Ketamine in Ear, Nose, and Throat (ENT) Patients Phase 4 Interventional Halted due to COVID 19; we believe we have adequate data for analysis Actual 93
NCT03435380 Suspended Promoting Breast Cancer Screening in Women Who Survived Childhood Cancer N/A Interventional Covid-19 Anticipated 291
NCT03841357 Suspended Preventing Extension of Oligoarticular Juvenile Idiopathic Arthritis JIA (Limit-JIA) Phase 3 Interventional Covid-19 Pandemic Anticipated 306
NCT04221594 Suspended Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery Observational The study activities are suspended due to COVID Anticipated 108
NCT02642562 Suspended Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN Phase 4 Interventional COVID-19 Pandemic Anticipated 1300
NCT02890368 Terminated Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides Phase 1 Interventional Actual 56
NCT03039686 Terminated Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy Phase 2/Phase 3 Interventional A pre-planned futility analysis indicated lack of efficacy Actual 166
NCT03079882 Suspended VisR Ultrasound for Noninvasively Monitoring Renal Allograft Health Observational Suspended due to COVID-19 risks Anticipated 100
NCT03258541 Terminated Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy N/A Interventional Surgical access not facilitated- residues of hydrogel. Actual 2
NCT04391699 Withdrawn Evaluation of Prophylactic Heated Humidification on Obstructive Sleep Apnea (OSA) Patient Short Term Compliance to CPAP Therapy N/A Interventional cancelled before initiation Actual 0
NCT03277742 Withdrawn Joint Management of DM2 and Pulmonary TB in Orizaba, Veracruz N/A Interventional Due to safety reasons. The region was considered too dangerous. Actual 0
NCT03508453 Withdrawn IC14 for Treatment of Amyotrophic Lateral Sclerosis Phase 2 Interventional Study will not be conducted due to lack of funding Actual 0
NCT03617874 Suspended PC4PrEP: Integrating PrEP Into Primary Care N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 219
NCT03691376 Suspended Genetically Engineered Cells (NY-ESO-1 TCR Engineered T Cells and HSCs) After Melphalan Conditioning Regimen in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Phase 1 Interventional Temporarily Suspended due to COVID-19 Anticipated 18
NCT03937999 Suspended Bezlotoxumab as Secondary Prophylaxis for C. Difficile in High-risk Hospitalized Patients Exposed to Antibiotics. Phase 4 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval Anticipated 50
NCT04007315 Suspended SaeboGlove Therapy for Severe Upper Limb Disability and Severe Hand Impairment After Stroke N/A Interventional COVID-19 Anticipated 110
NCT04049578 Terminated A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Balovaptan in Children With Autism Spectrum Disorder Phase 1 Interventional Recent analysis of Phase II balovaptan data in paediatric ASD did not support the continuation of this study. No new safety concerns were identified. Actual 2
NCT04063709 Suspended Transcutaneous ARFI Ultrasound for Differentiating Carotid Plaque With High Stroke Risk N/A Interventional Suspended due to COVID-19 risks Anticipated 80
NCT02465034 Suspended Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 75
NCT02682082 Terminated EUS Guided Neurolysis Celiac Block w/wo Bupivacaine in Patient Being Treated Palliatively for Pancreatic Cancer N/A Interventional Closed by CHUM REB for incomplete documentation of research activities. Actual 22
NCT02685332 Suspended Phase I Dose Escalation of Single Fraction Adjuvant Stereotactic Body Partial Breast Irradiation Early Stage Breast CA Phase 1 Interventional Due to COVID-19 Anticipated 75
NCT02694965 Suspended Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma Observational COVID-19; enrollment will resume when local guidance is updated Anticipated 100
NCT02788019 Terminated Adductor Canal Mid-thigh and Adductor Canal Distal Thigh: Is Cutaneous Sensory Blockade Similar Among Block Techniques? Phase 4 Interventional Unable to complete the sample size needed for 80% power due to changes in surgical approach to adductor block usage. Anticipated 68
NCT02834754 Withdrawn Vedolizumab Post Op Study Phase 2 Interventional Limited time for enrollment of required number of subjects Actual 0
NCT02944578 Suspended Topical Curcumin for Precancer Cervical Lesions Phase 2 Interventional The study activities are on hold due to COVID-19 Anticipated 40
NCT03079297 Suspended Rapid Antidepressant Effects of Leucine Phase 2 Interventional Covid-19 Anticipated 40
NCT03353272 Suspended The Influence of a Cognitive Behavioral Approach on Changing Patient Expectations in Shoulder Pain N/A Interventional COVID-19 institutional policy Actual 33
NCT03433261 Suspended Ketogenic Diet for Reduction of CNS Oxygen Toxicity in Working Divers N/A Interventional Due to COVID-19 temporary suspension of in-person, non-essential research at Duke Anticipated 60
NCT03466398 Withdrawn Effects of a Remote Patient Monitoring Protocol on Glycemic Control in Adolescents With Type 1 Diabetes N/A Interventional Technical limitations encountered with the remote monitoring platform Actual 0
NCT03554278 Suspended Alteration of Stool Microbiota in Preterm Infants With Anemia Observational Covid-19 Anticipated 70
NCT03555981 Terminated Early Kangaroo Mother Care in Gambian Hospitalised Unstable Neonates N/A Interventional In response to COVID pandemic Actual 279
NCT03559634 Suspended Contraception Initiation Feasibility in the Pediatric ED N/A Interventional COVID Anticipated 400
NCT03599206 Suspended ONES Grant: CXCL10/CXCR3 Regulation of Ozone-Induced Epithelial Permeability Early Phase 1 Interventional COVID 19 Anticipated 100
NCT03646877 Suspended Mechanisms of Ozone-Induced Alterations in Efferocytosis and Phagocytosis Phase 1 Interventional COVID 19 Anticipated 70
NCT03647761 Suspended Does Wearing Tetra-Grip Improve Arm Function in Children Diagnosed With Neonatal Brachial Plexus Palsy? N/A Interventional Covid19 Actual 24
NCT03661645 Suspended Post-operative Methylprednisolone Taper Course for Orthopedic Surgery Phase 4 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 1000
NCT03667781 Suspended Therapeutic Drug Monitoring of Cardiac Medications Observational Covid-19 Anticipated 60
NCT03727893 Suspended Exercise Training and Manual Wheelchair Users With SCI N/A Interventional Temporarily paused due to COVID-19, expected to resume, IRB not suspended. Anticipated 30
NCT03748277 Terminated Comparison of Open and Minimally Invasive Surgical Techniques in the Treatment of Degenerative One-level Stenosis of Lumbar Spine N/A Interventional Recruitment terminated, all follow-up visits were canceled due to quarantine Actual 132
NCT03761498 Suspended Is There a Microbiome Associated With Poor Growth in Preterm Infants? Observational Covid-19 Anticipated 100
NCT03806556 Suspended A Pediatric Trial Using Tranexamic Acid in Thrombocytopenia Phase 1/Phase 2 Interventional Enrollment suspended for COVID-19 related reasons Anticipated 20
NCT03834779 Suspended HIV+ Substance Users Released From Jail N/A Interventional Covid 19 Anticipated 85
NCT03857490 Suspended Heat Therapy in Older Hypertensive Women N/A Interventional Covid-19 Anticipated 200
NCT03924245 Suspended Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers Phase 1/Phase 2 Interventional Pending site logistics Anticipated 73
NCT03976219 Suspended Measuring Evoked Potentials From the Spinal Cord and Dorsal Root Ganglion N/A Interventional Enrollment and in-person study activity suspended due to COVID-19 Anticipated 30
NCT03981835 Suspended Management of Antiplatelet Regimen During Surgical Procedures Observational [Patient Registry] Covid-19 Anticipated 1492
NCT03989635 Withdrawn Mechanistic Study of Anti-inflammatory Effects of Fevipiprant in Patients With Eosinophilic Asthma. Phase 2 Interventional Company Decision Actual 0
NCT03990740 Withdrawn Myofibroblastic Transformation Secondary to Epithelial-stromal Interactions in the Keratoconus Observational Logistical difficulties : protocol never finalized nor submitted Actual 0
NCT03999879 Suspended PhosphoRus, Proton Imaging and Amyloid BuRdEn (PREPARE) ON AMYLOID BURDEN AND COGNITION Observational Due to COVID 19 Anticipated 45
NCT04038099 Suspended Lessons on Urethral Lidocaine in Urodynamics Phase 4 Interventional Covid-19 Anticipated 70
NCT04061018 Suspended The Genetic, Protein, and Lipid Basis of Variation in Cholesterol Efflux Observational The study is temporarily suspended due to covid-19 policy. Anticipated 180
NCT04067505 Suspended Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study Phase 3 Interventional Adjustment of study protocol. Anticipated 240
NCT04106011 Suspended Cognitive Changes With Gabapentin Treatment Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 42
NCT04138953 Suspended Cortical Contributions to Motor Sequence Learning N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 60
NCT04156399 Terminated Acupuncture for Adults With Sickle Cell Disease (SCD): A Feasibility Study N/A Interventional COVID-19 pandemic Actual 6
NCT04156997 Suspended Extreme Lipids Repository Observational [Patient Registry] The study is temporarily suspended due to covid-19 policy. Anticipated 250
NCT04164732 Suspended Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy Phase 2 Interventional Only recruitment temporarily paused due to COVID-19 Anticipated 44
NCT04226833 Suspended A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function Phase 1 Interventional Recruitment is currently on hold due to COVID-19 pandemic Anticipated 24
NCT04254185 Suspended Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow N/A Interventional Enrollment and interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 378
NCT01318590 Terminated Prospective Study on Endoscopic Ultrasound (EUS) Celiac Bloc Efficacy in Chronic Pancreatitis Phase 3 Interventional Closed by CHUM REB for incomplete documentation of research activities. Actual 2
NCT04359901 Suspended Sarilumab for Patients With Moderate COVID-19 Disease Phase 2 Interventional Enrollment paused while protocol changes are pending review. Anticipated 120
NCT02026232 Suspended Metabolic Effects of Hydroxychloroquine N/A Interventional COVID-19 Anticipated 30
NCT02122666 Suspended Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome Observational COVID-19 Anticipated 100
NCT02617979 Terminated Improving Mental and Physical Health and Decreasing Hospital Readmission After Pancreatectomy Through Enhanced Patient and Caregiver Education and Engagement N/A Interventional Patients are receiving detailed packet from department and do not feel they need to go online for additional support. Actual 91
NCT03432208 Terminated A Pilot Study to Assess the Value of EUS vs EGD in Emergency Room Patients Referred for EGD N/A Interventional Closed by CHUM REB for lack of documentation related to the recruitment of participants. Actual 2
NCT03492177 Suspended A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension Phase 2 Interventional Screening on hold due to covid-19 measures Anticipated 60
NCT04392336 Suspended Tracking and Improving Trust/Respect N/A Interventional COVID-19 Anticipated 180
NCT03689244 Suspended A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or International Treatment Phase 3 Interventional Screening is temporarily halted due to COVID-19 Anticipated 280
NCT00992303 Suspended Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy Observational Due to CO-VID-19 Anticipated 10000
NCT02762604 Suspended Motor Imagery Intervention for Improving Gait and Cognition in the Elderly N/A Interventional Temporarily paused due to COVID-19. Expected to resume. Not a suspension of IRB Anticipated 48
NCT03540758 Suspended Regulation of Endogenous Glucose Production by Central KATP Channels Phase 2 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 45
NCT03566511 Suspended Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide Phase 2 Interventional Temporarily paused while we develop newer study techniques. We expect to resume; this is not a suspension of IRB approval. Anticipated 30
NCT03608163 Suspended Novel Approach for the Prevention of Hypoglycemia Associated Autonomic Failure (HAAF) Phase 4 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 45
NCT04160702 Suspended Using VR to Assess the Efficacy of a Motivational Interviewing Intervention to Increase Bystander Behaviors N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 140
NCT04384276 Suspended Weigh Easy: Simplifying Home Weight Monitoring for Infants N/A Interventional suspended due to COVID-19; no suspension of IRB Anticipated 325
NCT01201850 Terminated The Role of Bevacizumab in the Treatment of Radiation Necrosis in Children With Central Nervous System Tumors N/A Interventional Poor accrual Actual 8
NCT01486134 Terminated Major RF Ablations of Hepatomas Under MR Thermometry Monitoring N/A Interventional For technical reasons Actual 15
NCT04388371 Suspended Glutamine PET Imaging in LAM Phase 1 Interventional Due to COVID 19 Pandemic Anticipated 5
NCT01977417 Terminated Inflammation Inhibition in Prediabetic Humans Phase 2 Interventional No funding Actual 21
NCT02002507 Withdrawn Jugular Venous Flow Neurosurgical Patients Observational We faced technical problem before conducting this study Actual 0
NCT02109237 Withdrawn Sleep Disorders in Bronchiolitis Obliterans Syndrome 2&3 N/A Interventional no funding Actual 0
NCT03058068 Withdrawn Human MesenchymAl Stem Cells Infusion in Patients With Cystic Fibrosis Phase 1 Interventional PI left the institution Actual 0
NCT03066596 Suspended Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 512
NCT03122912 Suspended Explore Effects of Dietary Fish Oil in Human Skin Phase 1 Interventional Enrollment and interactions/interventions paused due to COVID-19. Expected to resume in the future. This is not a suspension of IRB approval Anticipated 46
NCT03291340 Suspended Determining the Impact of Shunting and CerebroVascular Reactivity on 7T MRI (DISCoVeR 7T MRI) Observational Recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 42
NCT03128086 Terminated Weaning From Mechanical Ventilation in Neurological Patients N/A Interventional Because the principal investigator has moved to another hospital Actual 94
NCT03533400 Withdrawn Effectiveness of Jamboxx Respiratory Therapy Device: Study 1 N/A Interventional NHLBI has suggested the company focus on the other two ongoing trials Actual 0
NCT03582384 Withdrawn Use of Tocofersolan (Vedrop®) to Prevent or Treat Refractive Vitamin E Deficiency in Infants and Children Phase 2 Interventional Study never started Actual 0
NCT03361228 Terminated A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors Phase 1/Phase 2 Interventional Study was terminated early based on emerging data with epacadostat and pembrolizumab. Actual 5
NCT03722238 Suspended Actual Use and Compliance Study Of Ibuprofen 600 Mg Immediate Release/Extended Release Tablets In At-Risk OTC Consumers Phase 3 Interventional Management decision to temporarily suspend enrollment while the program is reassessed Anticipated 820
NCT03728569 Suspended Skin Barrier Dysfunction and the Role of Skin Barrier Restoration Early Phase 1 Interventional Enrollment and interactions/interventions paused due to COVID-19. Expected to resume in the future. This is not a suspension of IRB approval Anticipated 45
NCT03767491 Withdrawn Waitlist-Control Trial of Smartphone CBT for Obsessive-Compulsive Disorder (OCD) N/A Interventional Study must be registered under the sponsor instead of the site, so we have created a new posting in the sponsor's account. Actual 0
NCT03769350 Withdrawn Waitlist-Control Trial of Smartphone CBT for Major Depressive Disorder (MDD) N/A Interventional Study must be registered under the sponsor instead of the site, so we have created a new posting in the sponsor's account. Actual 0
NCT03769363 Withdrawn Waitlist-Control Trial of Smartphone CBT for Social Anxiety Disorder (SAD) N/A Interventional Study must be registered under the sponsor instead of the site, so we have created a new posting in the sponsor's account. Actual 0
NCT03861611 Suspended A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain. Phase 4 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 198
NCT04102254 Suspended Thalamic Stimulation for Epilepsy Study N/A Interventional Lead acquisition from company & COVID-19 restrictions Anticipated 15
NCT04106973 Suspended Mesothelioma Early Detection by VOCs Observational Recruitment suspended secondary to social distancing directive associated with Covid-19 Anticipated 300
NCT04203238 Suspended Potato Research for Enhancing Metabolic Outcomes N/A Interventional Due to the SARS CoV2 pandemic Anticipated 36
NCT04244682 Suspended rTMS Brain Stimulation and Cognition N/A Interventional Enrollment is suspended due to COVID-19. Anticipated 80
NCT04252417 Terminated HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects Phase 1 Interventional Due to other Phase 3 trial failure to meet primary endpoint Actual 15
NCT04252430 Terminated RI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Renal Impaired Patients and Healthy Subjects Phase 1 Interventional Due to other phase 3 trial failure to meet primary endpoint Actual 24
NCT04256148 Suspended ALXN1830 in Patients With Warm Autoimmune Hemolytic Anemia Phase 2 Interventional Study is stopped due to the COVID-19 pandemic as WAIHA patients may be at higher risk of contracting disease based on SOC treatments. Anticipated 32
NCT02824848 Terminated Perception-Action Approach vs. Passive Stretching for Infants With Congenital Muscular Torticollis N/A Interventional Study stopped due to COVID-19 pandemic and will not resume. Actual 32
NCT03055585 Terminated Applying Wolbachia to Eliminate Dengue N/A Interventional Distancing and movement restrictions of the COVID-19 emergency response made continuation of clinic-based and field entomological trial activities infeasible Actual 8173
NCT04004845 Suspended Labor Protocol Study Observational Temporarily paused due to COVID19, expected to resume. This is not a suspension of IRB approval Anticipated 740
NCT04266262 Suspended High-Intensity Training for Men With Prostate Cancer on Active Surveillance: A Feasibility Study N/A Interventional All research activities were suspended as a result of COVID-19. Anticipated 36
NCT03247231 Suspended Banding Without Resection in Small Subepithelial Tumours Observational [Patient Registry] Due to SARS-CoV2 (Covid-19) pandemia Anticipated 157
NCT03284346 Terminated Exercise in Targeting Metabolic Dysregulation in Stage I-III Breast or Prostate Cancer Survivors N/A Interventional PI left Actual 23
NCT01059513 Withdrawn Hypo-fractionated Stereotactic Body Radiotherapy for Localized Prostate Cancer Observational No participants enrolled Actual 0
NCT01605318 Withdrawn Dose Finding Study of Once or Twice Weekly IMMU-130 in Metastatic Colorectal Cancer Phase 1/Phase 2 Interventional No patients are enrolled in any studies conducted under this IND Actual 0
NCT02645487 Suspended Stereotactic Radiosurgery (SRS) for Brain Metastasis N/A Interventional Failed Audit; it was due to safety concerns after annual DSMC review, specifically safety assessments not being performed per protocol Anticipated 180
NCT02802293 Suspended Treatment of Depression With Connectivity Guided Robotically Delivered rTMS N/A Interventional Study temporarily suspended due to COVID-19 pandemic Anticipated 150
NCT03052517 Terminated Study of Safety of QAW039 in Patients With Asthma Inadequately Controlled on Standard-of-care Asthma Treatment Phase 3 Interventional Company Decision Actual 2541
NCT03171545 Suspended Enhancing the Cardiovascular Safety of Hemodialysis Care (Dialysafe) N/A Interventional Enrollment is temporarily paused due to COVID-19 and is expected to resume in the future. This is not a suspension of IRB approval. Anticipated 2100
NCT03304821 Suspended Granulocyte-Macrophage Stimulating Factor (GM-CSF) in Peripheral Arterial Disease Phase 2 Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 176
NCT03335878 Suspended Brain Health and Development With T1DM Observational Due to COVID 19. Anticipated 200
NCT03557502 Suspended Heat Therapy Versus Exercise Training in Hypertension N/A Interventional All Clinical Trials at Univ Oregon halted due to COVID-19 pandemic Anticipated 50
NCT03594994 Suspended Metabolic Effects of Sleep Extension in People With Obesity N/A Interventional Suspended due to Covid-19 Anticipated 40
NCT03646669 Suspended Symptom Perception N/A Interventional COVID-19 Anticipated 80
NCT03701828 Suspended Liver Health and Metabolic Function in People With Obesity N/A Interventional Suspended due to Covid-19 Anticipated 30
NCT03764488 Suspended A Study to Evaluate Safety, Tolerability, and Distribution of a Microdose of Radiolabeled BIIB067 (99mTc-MAG3-BIIB067) Co-administered With BIIB067 to Healthy Adults Phase 1 Interventional Healthy volunteer enrollment on hold at site due to COVID-19 pandemic. Anticipated 20
NCT04079855 Suspended Monell USDA Taste Test Study N/A Interventional corona virus Anticipated 128
NCT04259385 Suspended Effects of Sugary Drink Warning Labels on Parent Choices N/A Interventional Coronavirus stay-at-home orders prevent in-person data collection Anticipated 810
NCT04286243 Suspended Prevention of Cervical Cancer Through an HPV-based Screen-and-treat Strategy in Malawi N/A Interventional In response to COVID-19, implementation has been put on hold at sites that had already launched. Anticipated 9200
NCT02052921 Terminated Observation Versus Surgical Resection in Patients With Rectal Cancer Who Achieved Complete Clinical Response After Neoadjuvant Chemoradiotherapy N/A Interventional During the execution time foreseen in the project, the expected number of patients was not reached. Actual 13
NCT02417688 Suspended PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis Phase 1 Interventional temp suspend due to covid Anticipated 22
NCT02567110 Suspended Magnetic Resonance Spectroscopy (MRS) in Midlife Depression Observational Enrollment is temporarily suspended due to COVID-19. Anticipated 145
NCT02741648 Suspended RBC Irradiation, Anemia and Gut Injury Observational Enrollment is temporarily suspended due to COVID-19; follow up for current participants is continuing. Anticipated 220
NCT02784509 Suspended Translational Investigation of Growth and Everyday Routines in Kids Observational Temporary suspension due to COVID-19 stay-at-home order; will resume when clinic re-opens Anticipated 342
NCT02796144 Terminated MEtformin and Lorcaserin for WeighT Loss in Schizophrenia Phase 4 Interventional The FDA advised of a possible health risk associated with lorcaserin and the drug is being withdrawn. Actual 71
NCT02945644 Suspended Trazodone Dose Tolerance and APAP Adherence Phase 1 Interventional COVID19 pandemic Anticipated 45
NCT03176134 Suspended A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to <12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018) Phase 3 Interventional COVID-19 Anticipated 120
NCT03281499 Suspended Transoral Robotic Surgery and Tailored Radiotherapy in Unknown Primary and Small Squamous Cell Head and Neck Cancer N/A Interventional The study accrual is currently on hold until further notice due to the COVID-19 Pandemic. Anticipated 25
NCT03408340 Suspended Paravertebral Nerve Blocks in Neonates Phase 4 Interventional The study activities are suspended due to COVID-19 Anticipated 30
NCT03546335 Suspended Zr-89 Cimzia PET Imaging Rheumatoid Arthritis Phase 1 Interventional Lapse in study funding. Anticipated 10
NCT03660098 Suspended Mirror Box Therapy as a Treatment Option for Functional Movement Disorders Observational Due to COVID-19 virus Actual 14
NCT03840486 Suspended Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements Phase 4 Interventional Study is temporarily suspended due to COVID-19. Anticipated 116
NCT03951363 Suspended iControl Chronic Kidney Disease N/A Interventional Suspended due to COVID-19 restrictions (funding and in-person visits) Anticipated 40
NCT03975491 Suspended The Exercise And Colon Cancer Treatment Trial N/A Interventional Temporarily suspended due to COVID-19. The study is planned to re-open. Suspension does not relate to withdrawal of IRB approval. Anticipated 60
NCT04096482 Suspended Safety and Effectiveness of the Peregrine Drivable ENT Scope for Endoscopy of the Paranasal Sinuses N/A Interventional Study is temporarily on hold pending updates and supplies from the sponsor. Anticipated 30
NCT04180540 Suspended Comparison of Percutaneous Closure to Manual Compression for Hemostasis N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 130
NCT04246567 Suspended Evaluation of the Effect of Sevoflurane and Propofol Hypotensive Anesthesia on Blood Antioxidant Levels and HIF 1 Levels N/A Interventional Ethics approval is expected from the pharmaceutical institution for the study which has received the local ethics committee approval. Actual 60
NCT04278963 Suspended Yinhu Qingwen Decoction for the Treatment of Mild / Common CoVID-19 Phase 2/Phase 3 Interventional There were no eligible patients in the paticipated centers. Anticipated 300
NCT04310865 Suspended Yinhu Qingwen Granula for the Treatment of Severe CoVID-19 Phase 2/Phase 3 Interventional There were no eligible patients with CoVID-19 in the paticipated centers. Anticipated 116
NCT04382677 Suspended Families Together: Intervention for Reunified Families N/A Interventional COVID-19 social distancing restrictions--temp halt of recruitment & intervention Anticipated 255
NCT02160288 Terminated Effects of Botox in Obstructed Defecation Syndrome Phase 2 Interventional Low recruitment Actual 1
NCT03437512 Suspended Non-invasive Brain Stimulation in Adults Who Stutter N/A Interventional Covid-19 paused human subjects research at study site Anticipated 50
NCT03629964 Withdrawn Study to Develop Head Stabilizer for Use During Brain Radiation Therapy N/A Interventional PI left site. Actual 0
NCT02260141 Terminated Treating Alzheimer's and Dementia With D-ribose N/A Interventional unable to get adequate enrollment Actual 3
NCT02886936 Suspended Immediate Fit Using Innovative Technology Transtibial Prosthesis N/A Interventional COVID 19 is causing us to suspend bringing patients into the hospital for safety reasons. Anticipated 20
NCT02888587 Suspended The Innervation of Human Gut Sensory Epithelial Cells Observational COVID-19 Restrictions Anticipated 50
NCT03081026 Suspended Transphyseal Vs. Physeal Sparing ACL Reconstruction in Skeletally Immature Patients: Risk of Subsequent Lower Extremity Growth Deformity Observational COVID19 Anticipated 100
NCT03179943 Suspended Atezolizumab + Guadecitabine in Patients With Checkpoint Inhibitor Refractory or Resistant Urothelial Carcinoma Phase 2 Interventional Pending Interim Analysis Anticipated 53
NCT03303950 Terminated Busulfan, Fludarabine, Donor Stem Cell Transplant, and Cyclophosphamide in Treating Patients With Multiple Myeloma or Myelofibrosis Phase 2 Interventional Original PI left institution, new PI decided to end study Actual 6
NCT03463395 Withdrawn Efficacy of Reza Band for the Treatment of Laryngopharyngeal Reflux N/A Interventional Funding for this study has ended and we were unable to enroll any subjects Actual 0
NCT03630601 Suspended Photoacoustic Imaging in Diagnosing Changes in Tumors in Participants With Breast Cancer, Sarcoma, Skin Cancer, or Soft Tissue Malignancy and Healthy Volunteers N/A Interventional Suspended Temporarily due to COVID-19 Anticipated 90
NCT03650400 Terminated Pharmacokinetics, Safety and Tolerability of Fevipiprant Delivered Via a Once Daily Chewable Tablet in Children Aged 6 to < 12 Years With Asthma Phase 2 Interventional Company Decision Actual 12
NCT03657147 Suspended Improving African American Glaucoma Patient Involvement in Visits and Outcomes N/A Interventional Study halted prematurely due to COVID-19 but potentially will resume. Follow-up visits continue virtually. Anticipated 380
NCT03806192 Suspended Feasibility of Partners in Care Program for Caregivers of Patients With Acute Myeloid Leukemia N/A Interventional COVID19 Suspension Anticipated 40
NCT03881735 Suspended Enasidenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia With an IDH2 Gene Mutation Phase 2 Interventional Temporarily Suspended due to COVID 19 Anticipated 86
NCT03956238 Suspended Alcohol Myopia, Objectification, and Sexual Assault N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 360
NCT04032717 Suspended Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT) Phase 1 Interventional Due to the COVID-19 pandemic, study has been temporarily halted and will resume in the future Anticipated 21
NCT04037072 Suspended Efficacy of Topical Mitomycin C for Complex Benign Esophageal Anastomotic Strictures Phase 2 Interventional Due to COVID-19 Anticipated 82
NCT04048122 Suspended Feasibility and Effect of a Strategy-Based Cognitive Intervention for Parkinson Disease N/A Interventional Temporarily paused due to COVID-19 and expected to resume. Anticipated 60
NCT04199585 Terminated Safety and Tolerability of Lu AF95245 in Healthy Young Men Phase 1 Interventional new safety data from another study Actual 18
NCT04203186 Withdrawn A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI) N/A Interventional Funding was lost due to the COVID19 Pandemic Actual 0
NCT04357535 Terminated Prognosis of Coronavirus Disease 2019 (COVID-19) Patients Receiving Receiving Antihypertensives Observational We cannot meet number of subjects as recently published similar studies. Actual 17
NCT01864291 Terminated Auditory Brainstem Implant (ABI) in Pediatric Non-Neurofibromatosis Type 2 Subjects N/A Interventional Closed by IRB Actual 9
NCT04068532 Suspended A Study to Explore Pharmacodynamic Effects of BIIB104 on Brain Circuitry in Healthy Participants Phase 1 Interventional Healthy volunteer enrollment on hold at site due to COVID-19 pandemic. Anticipated 30
NCT04188301 Suspended Safety and Efficacy of IDA for Onchocerciasis Phase 2 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 201
NCT04230681 Suspended Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery Early Phase 1 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 300
NCT04246476 Suspended Sing for Your Saunter Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 60
NCT03519087 Terminated Nonarthritic Hip Disease Evaluation And Treatment N/A Interventional The planned 15-month recruitment period was completed. Actual 112
NCT04258670 Suspended Spontaneous Antigenemia in Loiasis Observational [Patient Registry] Study temporarily paused due to COVID-19 and expected to resume. Anticipated 60
NCT04258774 Suspended The Effect of Respiratory Challenge on the BOLD Signal N/A Interventional Temporarily halted due to COVID-19 Anticipated 48
NCT03637868 Withdrawn Eribulin in Brain Metastases From HER2-negative Breast Cancer Phase 2 Interventional no enrollment Actual 0
NCT03867045 Suspended Development of a Cabozantinib (Cabometyx) Symptom Management Application for Use in Patients With Renal Cancer N/A Interventional Study deemed non-essential under COVID pandemic, Anticipated 9
NCT04021914 Suspended Feasibility of EnChroma Use in the Emergency Department Setting N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 10
NCT04376736 Suspended Home Visits for Patients at Risk for Appointment No-shows N/A Interventional Covid-19 Anticipated 400
NCT02447874 Suspended Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease Phase 1/Phase 2 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 21
NCT02567448 Terminated Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA N/A Interventional Failed to accrue Actual 24
NCT02640209 Terminated Pilot Trial Of Autologous T Cells Engineered To Express Anti-CD19 Chimeric Antigen Receptor (CART19)In Combination With Ibrutinib In Patients With Relapsed Or Refractory CD19+ Chronic Lymphocytic Leukemia (CLL)Or Small Lymphocytic Lymphoma (SLL) Early Phase 1 Interventional Study is terminated due to administrative reasons. Actual 20
NCT02664337 Suspended Conjoint Analysis of Patient Preferences in Joint Interventions N/A Interventional Suspended due to COVID Anticipated 2310
NCT02918175 Suspended Mobile Health Behavioral Intervention in Patients With Heart Failure and Diabetes Mellitus N/A Interventional The study is halted due to COVID-19. Will update once enrollment resumes. Anticipated 200
NCT02978118 Suspended Exploring Relevant Immune-based Biomarkers and Circulating Tumor Cells During Treatment With Immune Checkpoint Inhibitors in Genitourinary Malignancies (CTC Immune Based Biomarkers) Observational study deemed non-essential under COVID-19 pandemic Anticipated 55
NCT03248765 Suspended Human Brain Adaptation to Chronic Pain and Its Effects on Opioid Use Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 60
NCT03253328 Suspended N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes N/A Interventional No one is currently receiving treatment and enrollment is of course on hold. Subjects being unblinded to perform interim analysis. Anticipated 50
NCT03352414 Terminated Trial Investigating Alvimopan for Enhanced Gastrointestinal Recovery After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Phase 2 Interventional stopped by sponsor Actual 58
NCT03399448 Terminated NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells) Phase 1 Interventional Sponsor has terminated trial to pursue other targets. Actual 3
NCT03577119 Suspended Full-fat Yogurt and Glucose Tolerance N/A Interventional Accrual on hold due to temporary pandemic research policy. Anticipated 32
NCT03612193 Suspended Role of the Gut Microbiome in Complex Regional Pain Syndrome Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 140
NCT03670017 Suspended Glucose Time-In-Range Development Evaluation N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 50
NCT03697564 Suspended Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic Cancer Achieving Disease Control in Response to First-line Chemotherapy (GemCaN Trial). Phase 2 Interventional Working on getting accurate information for patients interested in the study. Anticipated 40
NCT03794258 Withdrawn Triple or Quadruple Combination DAAs Treatment for Subjects With HCV GT 1b Infection Phase 2 Interventional Can not recruit the patients due to the pandemic of COVID-19 Actual 0
NCT03881137 Suspended Improved Function and Quality of Life for Older Patients Receiving Radiotherapy, Part II N/A Interventional Enrolment stop 13.03.20 due to Corona pandemic. Continued suspension decided 28.04. Reopening estimated 01.10.20 Anticipated 162
NCT03926611 Suspended Dose-finding Study to Evaluate Efficacy and Safety of LOU064 in Patients With CSU Inadequately Controlled by H1-antihistamines Phase 2 Interventional COVID-19 Pandemic Anticipated 308
NCT03940651 Suspended Cardiac and Renal Biomarkers in Arthroplasty Surgery Phase 4 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 140
NCT04006496 Suspended AML Expressive Writing N/A Interventional COVID-19 restrictions Anticipated 30
NCT04020887 Suspended Telemedicine Control Tower for the Post-Anesthesia Care Unit N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 500
NCT04157179 Suspended Cerebral Oxygen Metabolism in Children N/A Interventional Temporarily halted due to COVID-19 Anticipated 350
NCT03382899 Terminated Study of Pegilodecakin (LY3500518) With Pembrolizumab Compared to Pembrolizumab Alone First-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer Phase 2 Interventional The CYPRESS-1 trial was closed early after the planned final analysis because the risk benefit ratio is unfavorable. Actual 99
NCT03382912 Terminated Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer Phase 2 Interventional The CYPRESS-2 trial was closed early after the planned final analysis because the risk benefit ratio is unfavorable. Actual 52
NCT03532490 Suspended Trial of Roflumilast in Asthma Management (TRIM) Phase 2 Interventional Suspended due to COVID-19 public health emergency. Anticipated 38
NCT03634397 Suspended Predicting Ipsilesional Motor Deficits in Stroke With Dynamic Dominance Model N/A Interventional Temporarily suspended due to Pandemic Actual 60
NCT03745781 Terminated Open-Label Placebo for Functional Dyspepsia Early Phase 1 Interventional low enrollment Actual 21
NCT03908827 Withdrawn BMAC in Severe Hip or Knee Osteoarthritis Awaiting Arthroplasty Phase 2/Phase 3 Interventional Change of study design Actual 0
NCT03938103 Suspended Evaluation of an Enhanced Delivery Model for Go NAPSACC N/A Interventional Temporarily halted as a precautionary measure due to COVID-19 pandemic. Anticipated 1189
NCT04129398 Suspended MK-8228 (Letermovir) in the Prevention of Human Cytomegalovirus (CMV) Infection and Disease in Adult Japanese Kidney Transplant Recipients (MK-8228-042) Phase 3 Interventional COVID-19 Anticipated 20
NCT04130295 Suspended Influence of Wearable Intensive Nerve Stimulation on Spasticity and Function in Persons With Spinal Cord Injury N/A Interventional Covid-19 Anticipated 12
NCT04149600 Suspended Identification of Genetic Causes of Calcific Aortic Valve Disease Observational Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 1000
NCT04203147 Suspended Home-based Diabetes-Modified Behavioral Activation Treatment for Low Income Seniors With T2DM N/A Interventional Due to COVID-19, a partial suspension of human subjects research was put into effect for research involving direct contact with human subjects. Anticipated 300
NCT04243811 Withdrawn Efficacy of Low Level Laser Therapy on İnjection Pain N/A Interventional Due to the technical problem in the laser device,it has not started. Actual 0
NCT04341870 Suspended Study of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients: Sarilumab, Azithromycin, Hydroxychloroquine Trial - CORIMUNO-19 - VIRO Phase 2/Phase 3 Interventional DSMB recommendation (futility) Actual 27
NCT03454360 Terminated CHANGE Neo™ TA Registry With ACURATE Neo™ Aortic Bioprosthesis and ACURATE Neo™ TA Transapical Delivery System Observational Sponsor business decision unrelated to product safety or efficacy. Actual 106
NCT04063241 Suspended Parent Understanding of Discharge Instructions N/A Interventional Study suspended due to Covid-19 Anticipated 778
NCT04375189 Suspended High Risk Outpatient Intern-led Care (HeROIC) Clinic Initiative N/A Interventional Covid-19 Anticipated 150
NCT00005485 Suspended The Jackson Heart Study of Cardiovascular Disease Among African Americans Observational COVID-19 outbreak Actual 5306
NCT00734838 Suspended Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy N/A Interventional COVID-19 Anticipated 205
NCT01026571 Suspended Identification of Genetic Causes of Bicuspid Aortic Valve Disease Observational Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 4000
NCT01825369 Withdrawn Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood Flow Phase 1 Interventional Changes to cardiac surgery program Actual 0
NCT01980797 Suspended International Bicuspid Aortic Valve Consortium (BAVCon) Observational [Patient Registry] Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 10000
NCT02422875 Suspended Comparative Autoantibody and Immunologic Cell Marker Study Observational [Patient Registry] Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 1050
NCT02645942 Withdrawn L-carnitine for Reducing Cardio-metabolic Risk in Patients With Obstructive Sleep Apnea N/A Interventional Study stopped due to organization reasons. Actual 0
NCT02700763 Terminated [18F]Dabrafenib Molecular Imaging in Melanoma Brain Metastasis N/A Interventional Due to the very low inlcusion rate and the current COVID-19 pandemic. Actual 1
NCT02856373 Terminated Renal Nerve Stimulation and Renal Denervation in Patients With Sympathetic Ventricular Arrhythmias Phase 2 Interventional Low enrollment number Actual 9
NCT02953431 Suspended Increased Lung Volume as Controller Therapy for Asthma Phase 1/Phase 2 Interventional COVID-19 Institution Suspension of Research Anticipated 29
NCT03001518 Suspended Immunologic Signatures Following Surgery for Pancreatic Cancer Observational COVID Anticipated 30
NCT03148288 Terminated Vitamin D Supplementation in IBS N/A Interventional low enrollment Actual 7
NCT03201549 Suspended The Effects of Increased Fructose Ingestion on FGF-21 Levels in Humans N/A Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 15
NCT02038153 Terminated Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant Phase 1/Phase 2 Interventional Low accrual Actual 3
NCT01075776 Withdrawn The Effects of C-type Natriuretic Peptide on Human Forearm Blood Vessels N/A Interventional Lack of funding Actual 0
NCT02813447 Suspended Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD) N/A Interventional COVID-19 hold Anticipated 30
NCT04316000 Suspended Anxiety and Fear of Cancer Before and After Banding Without Resection in Small SET Management (QUALI-BANDING-SET) Observational Due to SARS-CoV2 (Covid-19) pandemia and its implications for outcomes bias. Anticipated 150
NCT02277613 Terminated A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction Phase 2 Interventional Anticipated 90
NCT03456778 Suspended Achilles Tendinopathy Shear Wave Elastography Study N/A Interventional The study activities are suspended due to COVID-19 pandemic Anticipated 15
NCT02560805 Suspended Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV Phase 2 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 134
NCT03121911 Withdrawn Effects of Interval Physical Training on Expiratory Flow Limitation in Recent Myocardial Infarction N/A Interventional technical problems in equipment Actual 0
NCT03220711 Suspended Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon Phase 1 Interventional Enrollment and interactions/interventions temporarily paused due to COVID-19 & will resume in the future. No suspension of IRB approval. Anticipated 50
NCT03588715 Suspended Peg-Interferon Alpha 2b Combined With Two Intravenous Broadly HIV-1 Neutralizing Antibodies 3BNC117 and 10-1074 (BEAT-2) Phase 1 Interventional Suspended due to COVID-19 Anticipated 21
NCT03737617 Suspended Immunoglobulin Replacement Therapy for Immunoglobulin G Subclass 2 Deficient Patients With Bronchiectasis Phase 4 Interventional Cant obtain IMP Anticipated 20
NCT03858920 Suspended The Liver in the World Trade Center Health Program General Responder Cohort and Controls Observational COVID-19 Anticipated 400
NCT03927248 Withdrawn PAC-1 for Treatment of Refractory, Metastatic Kidney Cancer Phase 1/Phase 2 Interventional Withdrawn Actual 0
NCT03952858 Withdrawn Telerehabilitation in Geriatric Patients at Aarhus University Hospital, Denmark N/A Interventional Too few elible patients but only one gave informed consent Actual 0
NCT04261140 Withdrawn Clinical Evaluation of Four Aesthetic Restorations in Non-carious Cervical Lesions N/A Interventional required license Actual 0
NCT03455556 Terminated Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer Phase 1 Interventional slow accrual Actual 1
NCT01570361 Terminated Atrial Fibrillation Progression Trial Phase 4 Interventional The sponsor decided to terminate the study early due to enrolment not proceeding in accordance with expectations, independently from the study outcome. Actual 255
NCT01919489 Suspended Liraglutide Hospital Discharge Trial Phase 4 Interventional Recruitment is suspended due to COVID-19. Study visits for currently enrolled subjects are ongoing per an IRB approved amendment to reflect the pandemic status Anticipated 330
NCT02683473 Suspended Measurement of Energy Metabolism in Infants Observational Study temporarily paused due to COVID-19 and is expected to resume. This is not a suspension of IRB approval. Anticipated 40
NCT02711592 Terminated Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study N/A Interventional Lack of enrollment Actual 4
NCT02892604 Terminated Study the Feasibility of Permanent Use of inControl for the Treatment of Type 1 Diabetes N/A Interventional not enough participants Actual 3
NCT03048227 Terminated Can Continuous Glucose Measurements Help Diabetic Patients Treated With an Implantated Pump? N/A Interventional CGM Navigator isn't longer available (October 11, 2019) Actual 15
NCT03287778 Suspended Randomized Controlled Trial of Pyridoxine for Tardive Dyskinesia N/A Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 50
NCT03336528 Suspended A Trial Comparing Insulin Degludec and Glargine U100 for Management of Hospitalized and Discharged Patients With Type 2 Diabetes Phase 4 Interventional Recruitment is suspended due to COVID-19. Study visits for currently enrolled subjects are ongoing per an IRB approved amendment to reflect the pandemic status. Anticipated 180
NCT03338998 Suspended Efficacy, Safety and Tolerability of BAF312 Compared to Placebo in Patients With Intracerebral Hemorrhage (ICH). Phase 2 Interventional Only recruitment temporarily paused due to Covid-19. Anticipated 60
NCT03401697 Suspended Eliminating Hepatitis C Virus Observational COVID-19 Actual 52
NCT03446612 Suspended Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF) Phase 2 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 50
NCT03562767 Suspended Cognitive Behavioral Therapy for African Americans With Uncontrolled Type-2 Diabetes N/A Interventional Study activities are suspended due to COVID-19 pandemic Anticipated 45
NCT03577106 Suspended A Pilot fMRI Study of TMS in Late-Life Severe Worry N/A Interventional Due to the Covid-19 pandemic Anticipated 40
NCT03673865 Suspended The Use of 3D Printing in Orbital Fractures N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 60
NCT03704584 Suspended Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone Phase 4 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 1000
NCT03838536 Suspended Synergistic Activity of Human Milk Nutrients and Infant Cognition N/A Interventional Suspended with COVID-9 pandemic; will resume post-pandemic. Anticipated 84
NCT03877068 Suspended Dexcom G6 Intervention Study N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 185
NCT03922581 Suspended Primary-Care Based Mindfulness Intervention N/A Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 80
NCT00793884 Suspended Emory Latino Diabetes Education Program Observational Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 3000
NCT03929562 Suspended Alcohol Screening and Pre-Operative Intervention Research Study N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 90
NCT03938350 Suspended Dialectical Behavior Therapy for Pregnant Women N/A Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 60
NCT03949244 Suspended Nailfold Capillary Blood Flow With Latanoprost Bunod Phase 4 Interventional COVID-19 Anticipated 60
NCT03958955 Suspended Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus. Phase 2 Interventional Trial put on hold due to COVID 19 pandemic. Anticipated 45
NCT03976596 Suspended Measurement of in Vivo Mitochondrial Capacity in Infants Observational Study temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 18
NCT04125680 Suspended English as a Second Language Health Literacy Program N/A Interventional "Enrollment is temporarily paused due to COVID-19 and is expected to reopen in the future. This is not a suspension of IRB approval." Anticipated 50
NCT04160078 Suspended Mindfulness IN-home for Diabetes and Sleep Health N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 20
NCT04176497 Suspended PSMA-PET/MRI Unfavorable-Risk Target Volume Pilot Study Phase 2 Interventional Recruitment temporarily paused due to COVID-19 and expected to resume. Anticipated 42
NCT04241484 Withdrawn Piezowave for Treatment on Lateral and Medial Elbow Tendinopathies N/A Interventional PI left the institution Actual 0
NCT02492854 Suspended Standard Versus PICO Dressings in Lower-Extremity Bypass Patients N/A Interventional Currently suspended due to Covid-19 pollicies. Anticipated 40
NCT03126760 Suspended Pilot Study to Assess the Efficacy & Safety of H.P. Acthar® Gel in Subjects With Relapsing-remitting Multiple Sclerosis Phase 4 Interventional Temporarily Suspended for COVID-19 Anticipated 66
NCT03529019 Suspended Nutrition in Patient With Critical Limb Ischemia Early Phase 1 Interventional Curretly suspended due to Covid-19 policies. Anticipated 30
NCT03682497 Terminated Study in HFpEF Patients to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium Phase 1 Interventional Attendance at study sites carries risk of COVID-19 infection. Non-attendance at planned study site visits has unacceptable study related patient safety risk. Actual 68
NCT04165083 Suspended Substudy 2: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Treatment-naïve Participants With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Positive Advanced Non-small Cell Lung Cancer (NSCLC ) (MK-3475-01B/KEYNOTE-01B) Phase 2 Interventional Business Reasons Anticipated 60
NCT04371159 Suspended A Comparative, Controlled Study to Evaluate the Clinical Accuracy of the Velieve U.S. UTI Urine Analysis Test System N/A Interventional Temporarily suspended due to COVID-19 Anticipated 375
NCT04183205 Suspended Predicting SSRI Efficacy in Veterans With PTSD Phase 4 Interventional Administrative Hold on Non-Critical, In-Person Interactions with Human Research Subjects in ORD-Funded Studies due to COVID-19 Anticipated 94
NCT00807482 Suspended Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease Observational Recruitment has been suspended during COVID-19 pandemic Anticipated 1800
NCT01763359 Terminated Hip Strength and Nerve Palsy After the Modified Stoppa Approach to Acetabular Fracture Reduction and Fixation Observational The original PI moved on from this facility as did other key personnel. The current PI decided to discontinue the study. Actual 43
NCT01133678 Terminated Study in Locally Advanced Squamous Cell Carcinoma of Head and Neck Phase 2 Interventional Primary endpoint reached futility boundary Actual 50
NCT03101046 Suspended Treatment of Metastatic Castrate Resistant Prostate Cancer Patients According to Circulating Tumor Cells Kinetic Phase 2 Interventional Temporary suspension since March 2020 due to COVID-19 pandemic Anticipated 792
NCT03365921 Suspended A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial) Phase 4 Interventional Because of the epidemic of COVID-19, the serum testing could not be continued Actual 360
NCT03438552 Suspended Efficacy of Repeat Stereotactic Radiation in Patients With Intraprostatic Tumor Recurrence Phase 1/Phase 2 Interventional Temporary suspension since March 2020 due to COVID-19 pandemic Anticipated 47
NCT04224844 Suspended Erector Spinae Plane Block for Carotid Endarterectomy N/A Interventional not recruiting, awaiting for changes in IRB Anticipated 34
NCT04253795 Suspended Nonintubated Versus Intubated Anesthesia in Video-assisted Thoracic Surgery N/A Interventional not recruiting, awaiting for changes in IRB Anticipated 60
NCT04263337 Suspended NFL LONG Prospective Study Observational Enrollment temporarily suspended during COVID-19 pandemic. Anticipated 250
NCT04274465 Suspended Application of Plasma Circulating HPV DNA Testing to Management of Cervical Intraepithelial Neoplasia Observational Due to COVID-19,expected to resume. This is not a suspension of IRB approval Anticipated 85
NCT02460835 Suspended A Pilot Study of Individualized Adaptive Radiation Therapy for Hepatocellular Carcinoma N/A Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 80
NCT04372966 Terminated Uncemented Versus Cemented Total Hip Arthroplasty for Displaced Intracapsular Hip Fractures N/A Interventional The Chief Investigator (John Keating) Actual 50
NCT02887157 Suspended Analyzing Retinal Microanatomy in ROP Observational Duke University suspended non-essential in-person research on 3/13/20. Study recruitment will reopen once Duke has resumed in-person non-essential research. Anticipated 160
NCT03015831 Terminated Effect of Low Dose ColchiciNe on the InciDence of POAF Phase 3 Interventional Statistical analysis of interim data showed no advantage of colchicine Actual 254
NCT03029104 Terminated Collagen Cross-Linking With Ultraviolet-A in Asymmetric Corneas Phase 2 Interventional Sufficient clinical results obtained to support study endpoints. Actual 2228
NCT03099356 Suspended Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 19
NCT03212352 Terminated Comparing Two Medical Treatments for Early Pregnancy Failure. Phase 4 Interventional Advised by DSMB based on interim-analysis, highly significant difference. Actual 342
NCT03300505 Suspended ARRx in Combination With Enzalutamide in Metastatic Castration Resistant Prostate Cancer Phase 1/Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 35
NCT03335280 Terminated 68Ga-citrate PET/MR Imaging for Glioma Observational Low Accrual Actual 2
NCT03464851 Terminated Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis Observational Low enrollment due to inclusion/exclusion criteria Actual 51
NCT03474965 Suspended Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients Phase 2 Interventional Only recruitment temporarily paused due to COVID-19. Anticipated 100
NCT03556904 Suspended FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE) Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 72
NCT03599583 Suspended The STOP-HPV Trial 3: Prompts Intervention N/A Interventional Temporarily suspending due to the impact of COVID-19 on practices. Anticipated 48
NCT03713268 Suspended Intraoperative OCT Guidance of Intraocular Surgery II Observational Duke University suspended non-essential in-person research on 3/13/20. Study recruitment will reopen once Duke has resumed in-person non-essential research. Anticipated 262
NCT03779867 Suspended Acute Exercise Intervention in Reducing Breast Cancer Risk in Healthy Participants N/A Interventional COVID19 Suspension Anticipated 100
NCT03781778 Suspended Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors Phase 2 Interventional COVID19 Suspension Anticipated 24
NCT03785873 Suspended Phase Ib/II Trial of Nal-Irinotecan and Nivolumab as Second-Line Treatment in Patients With Advanced Biliary Tract Cancer Phase 1/Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 40
NCT03829722 Suspended Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 40
NCT03932240 Suspended In Vivo Effects of Fibrinogen Concentrate (FC) Versus Cryoprecipitate on the Neonatal Fibrin Network Structure After Cardiopulmonary Bypass (CPB) Phase 3 Interventional All subject enrollment/follow up is on hold due to COVID-19 pandemic Anticipated 36
NCT04041908 Terminated Use of a Medical Food in Adults Undergoing Surgery N/A Interventional Low enrollment Actual 1
NCT04114929 Suspended Is Threshold-based Training Superior in Cardiac Rehabilitation N/A Interventional COVID-19 Anticipated 54
NCT04158752 Suspended Anti-CGRP for Inflamation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia Phase 4 Interventional Recruitment is temporarily suspended, related to COVID-19. Anticipated 20
NCT04248907 Withdrawn Transtibial Pin Lock Suspension at Varying Distraction Values Using a Modified Air Bladder Casting System N/A Interventional Due to Corona Virus guidelines, we have decided to withdraw the study. Actual 0
NCT04283058 Withdrawn Low Dose Ketamine Infusion for the Treatment of Resistant Depression Observational Covid-19 disruption of team Actual 0
NCT03840369 Suspended Pathophysiological Understanding and Treatment of PTSD: an rTMS Approach N/A Interventional COVID-19 pandemic has halted all recruitment and pushed back the anticipated study start date. Anticipated 80
NCT03869684 Terminated A Study to Assess the Safety, Tolerability and Effectiveness of MT-0814 for the Treatment of Age-related Macular Degeneration Phase 2 Interventional The study terminated for safety reasons Actual 14
NCT03871543 Suspended Late Night Study 2: End-of-Day Assessment of Asymptomatic and Symptomatic Soft Lens Wearers N/A Interventional To ensure the safety of participants during the COVID-19 pandemic, this clinical trial is suspended until further notice Anticipated 150
NCT03952182 Suspended Effect of Bracing Versus No Bracing in Stable Thoracolumbar Compression and Burst Fractures N/A Interventional Recruitment and follow up concerns during Covid-19 pandemic Anticipated 200
NCT03965962 Suspended Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines in a Simulated Post-Exposure Regimen in Adults Phase 3 Interventional Suspended (Due to COVID-19) Anticipated 606
NCT04109768 Withdrawn Hands On Nutrition Education to Improve Childhood Health N/A Interventional PI left university Actual 0
NCT04146532 Suspended Aspirin Effects on Emotional Reactions Early Phase 1 Interventional The study was suspended due to COVID-19 cessation of research activities in March of 2020 Anticipated 200
NCT04178772 Suspended Characterizing Successful Myopic Multifocal Contact Lens Wearers N/A Interventional To ensure the safety of participants during the COVID-19 pandemic, this clinical trial is suspended until further notice Anticipated 75
NCT04205396 Suspended CAREGIVER: A Trial to Improve the Burden and Distress of Caring for Persons With Decompensated Cirrhosis N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 90
NCT02314169 Suspended Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer Phase 2 Interventional Scheduled Interim Monitoring Anticipated 137
NCT03740009 Suspended Effects of a Tissue Selective Estrogen Complex (TSEC) on Depression and the Neural Reward System in the Perimenopause" Phase 4 Interventional COVID-19 pandemic Anticipated 25
NCT04223687 Suspended Impact of Warnings on Sugar-Sweetened Beverages N/A Interventional Recruitment has been suspended due to COVID-19. Anticipated 325
NCT04302727 Suspended Delicious Eating for Life in Southern Homes N/A Interventional Recruitment has been suspended due to COVID-19. Anticipated 360
NCT03214224 Suspended Remote Pulmonary Function Testing in Amyotrophic Lateral Sclerosis N/A Interventional Restrictions on recruitment and site visits due to COVID19 Actual 49
NCT00842283 Withdrawn Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target Observational Not a clinical trial study. Actual 0
NCT02169739 Suspended Remote Preconditioning Over Time To Empower Cerebral Tissue N/A Interventional COVID 19 restrictions Anticipated 60
NCT03073460 Withdrawn The Role of Fetal Ductus Arteriosus in Predicting Spontaneous Labour at Term N/A Interventional Not able to recruit any participants Actual 0
NCT03153397 Suspended Effect of Prebiotic Fiber- Enriched (scFOS) Enteral Feeding on the Microbiome in Neurological Injury Trauma Patients (PreFEED Microbiome Trial) N/A Interventional COVID-19 Anticipated 22
NCT03318627 Withdrawn Influence of Intraoperative Repair Tension on Postoperative Healing of Full-thickness Rotator Cuff Tears N/A Interventional No capacity to conduct the study Actual 0
NCT03381183 Suspended IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma Phase 1 Interventional Currently suspended due to COVID-19 policies Actual 7
NCT03404934 Terminated Clinical Study Verifying C-REX LapAid in Clinical Practice N/A Interventional Terminated by mutual agreement between the site and sponsor Actual 13
NCT03555786 Terminated MEV for Retroclavicular Approach to Infraclavicular Block Observational Failure of recruitment Actual 45
NCT03698669 Suspended Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings N/A Interventional Recruitment suspended due to COVID-19 policies; follow up continues remotely. Anticipated 250
NCT03779516 Terminated Effect of Nebulized Lidocaine on Postoperative Sore Throat N/A Interventional change in procedure Actual 110
NCT01459666 Terminated Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer Phase 4 Interventional Investigator left institution for private practice Actual 17
NCT04368910 Terminated Safety and Efficacy of Pyronaridine Artesunate Versus Chloroquine in Children and Adult Patients With Acute Plasmodium Vivax Malaria Phase 3 Interventional Due to slow recruitment the study was terminated prematurely by the Sponsor after 30 subjects had been included Actual 30
NCT02714140 Suspended Does Preference-based HIV Testing Increase Uptake in High Risk Populations? N/A Interventional COVID-related restrictions on in-person participant contact Anticipated 1200
NCT02939222 Withdrawn Impact of Buccal Bone Thickness on Pathological Peri-implant Bone Loss: A 3-year Prospective Cohort Study N/A Interventional Actual 0
NCT03152383 Suspended Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism N/A Interventional Enrollment suspended due to COVID-19, prescreening continues for future enrollment Anticipated 100
NCT03197922 Suspended Encopresis & MIE (DoD #2) Phase 3 Interventional Enrollment suspended due to COVID-19, prescreening continues for future enrollment Anticipated 112
NCT03487822 Suspended A Personalized Self-Management Program for Older Adults With Chronic Pain and Negative Emotions N/A Interventional Temporarily paused due to COVID-19, will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 140
NCT03570892 Suspended Tisagenlecleucel in Adult Patients With Aggressive B-cell Non-Hodgkin Lymphoma Phase 3 Interventional only recruitment temporarily paused due to COVID-19 Anticipated 318
NCT03932513 Terminated Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients Phase 2 Interventional Study was halted due to suspected liver injury in another study with Inarigavir Actual 8
NCT03979638 Terminated A Dose Escalation Study of BLU-5937 in Unexplained or Refractory Chronic Cough Phase 2 Interventional Trial was terminated due to the impact of the COVID-19 on trial activities. 68 patients with refractory chronic cough were enrolled with 52 completing treatment Actual 68
NCT04026750 Terminated Insulin Tolerance Test Study in Patients With Type 1 Diabetes Phase 1 Interventional Based on scientific data collected during the trial and high screen fail rate. Actual 5
NCT04059198 Terminated Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus Phase 2 Interventional Evidence of liver injury in a separate Inarigavir study Actual 5
NCT04170374 Suspended Survey of Procedures and Resources for Initiating Treatment of HIV in Africa (South Africa) Observational Currently suspended due to COVID-19 policies Anticipated 2708
NCT04368455 Suspended Virtual Immersive Communication Training on Recommending Immunizations N/A Interventional COVID-19 Anticipated 145
NCT03870919 Suspended Locoregional Treatment and Palbociclib in de Novo, Treatment Naive, Stage IV ER+, HER2- Breast Cancer Patients N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 200
NCT03968419 Suspended This Study Will Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC. Phase 2 Interventional Only recruitment temporarily paused due to COVID-19. Anticipated 110
NCT00837395 Terminated Inflammatory Mediators and microRNA Analysis in Premenstrual Asthma Observational Co-investigator left the university and another co-investigator died several years ago, making it impossible to complete the study as planned. Actual 24
NCT03429777 Withdrawn Validation of a Smartphone-Based Hearing-in-Noise Test (HearMe) N/A Interventional Lack of novelty of study Actual 0
NCT03566303 Terminated Rivaroxaban vs Warfarin in Patients With Metallic Prosthesis Phase 2/Phase 3 Interventional Coronavirus Pandemic Actual 50
NCT03599037 Suspended Inpatient ICOUGH RECOVERY App Version 2.0 N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 50
NCT03814746 Suspended Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients Phase 3 Interventional Only recruitment temporarily paused due to COVID-19 Anticipated 240
NCT03093493 Suspended Genetics of Ehlers-Danlos Syndrome Observational [Patient Registry] Currently suspended due to Covid-19 policies. Anticipated 300
NCT03755687 Suspended Art Therapy Pain Management Adolescents Pediatric ED N/A Interventional Paused until further notice due to COVID-19 restrictions Anticipated 50
NCT03873220 Suspended Monitoring Of Scratch Via Accelerometry In Children Observational Currently suspended due to Covid-19 policies. Anticipated 50
NCT03937531 Withdrawn Void Trials After Two Voiding Trials (TVT) N/A Interventional PI Left the Institution Actual 0
NCT03953794 Withdrawn Inflammatory Bowel Disease Tracker (IBD Tracker) Observational [Patient Registry] No accrual Actual 0
NCT03962725 Suspended Avoiding Neuromuscular Blockers to Reduce Complications Phase 4 Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 100
NCT03970837 Suspended Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs) Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 1500
NCT03980483 Suspended Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing Anticipated 1500
NCT03993002 Suspended DAMP-Mediated Innate Immune Failure and Pneumonia After Trauma - the Harvard-Longwood (HALO) Campus Area Consortium N/A Interventional Enrollment has temporarily paused due to COVID-19 and is expected to resume in the future; This is not a suspension of IRB approval Anticipated 50
NCT04075396 Suspended A Study of YH25448 in Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Positive Advanced Non-Small Cell Lung Cancer (NSCLC) Phase 1/Phase 2 Interventional Recruitment temporarily on hold due to COVID-19 situation. Anticipated 30
NCT04086745 Suspended A Study of Baricitinib in Participants With Rheumatoid Arthritis Phase 4 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 1300
NCT04088409 Suspended A Study of Baricitinib (LY3009104) in Participants From 2 Years to Less Than 18 Years Old With Active JIA-Associated Uveitis or Chronic Anterior Antinuclear Antibody-Positive Uveitis Phase 3 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 40
NCT04134728 Suspended Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 525
NCT04145440 Suspended Trial to Assess Safety and Efficacy of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN) Phase 1/Phase 2 Interventional Study recruitment paused due to COVID-19 pandemic Anticipated 30
NCT04153981 Suspended A Study of Insulin Glargine (LY2963016) in Adult Participants With Type 2 Diabetes in India Phase 4 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 250
NCT04237116 Suspended A Study of Secukinumab Treatment in Patients With Plaque Psoriasis and Coexisting Non-alcoholic Fatty Liver Disease (NAFLD) Phase 3 Interventional COVID-19 Pandemic Anticipated 90
NCT02766088 Terminated This Study Will Describe the Burden of DENgue Fever Virus (DENV) Illness Among Household Members Aged 6 Months to 50 Years of Selected Communities in Latin America and Southeast Asia N/A Interventional Actual 850
NCT03053063 Terminated Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) Phase 3 Interventional This study was terminated early due to lack of efficacy based on the results of the Week 48 analysis as prespecified in the clinical study protocol. Actual 883
NCT00602329 Terminated MRI in Predicting Response in Patients Receiving Combination Chemotherapy and Bevacizumab For Advanced or Metastatic Colorectal Cancer Phase 2 Interventional Due to Poor accrual Actual 5
NCT02011971 Suspended Cognitive Effects of Vinpocetine in Healthy Adults and Patients With Epilepsy Phase 1/Phase 2 Interventional We are now considering revision of the IND to determine maximum tolerated dose Anticipated 30
NCT02174016 Suspended The Ketogenic Diet for Pediatric Acute Brain Injury N/A Interventional Funding Anticipated 5
NCT02298166 Terminated Study of Crenolanib in Combination With Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Activating FLT3 Mutations Phase 3 Interventional The manufacturer Arog Pharmaceuticals Inc has terminated the Agreement Concerning the Support of an Investigator Initiated Trial this became valid on 2020/03/09 Actual 9
NCT02302885 Suspended Healthy Human Control Blood Collection for Validation of Biomarker Assay Observational Covid-19 Anticipated 70
NCT02671084 Terminated Sevoflurane and Percutaneous Coronary Intervention by Stent Phase 4 Interventional interim analysis suggests futility Actual 701
NCT02830334 Terminated Use of the Ask Suicide-Screening Questions (ASQ) in Pediatric Outpatient Settings Observational this study was determined by IRB not to be humans subjects research Actual 525
NCT02966223 Terminated A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver N/A Interventional Sponsor prematurely withdrew financial support. Actual 20
NCT03313999 Suspended Measuring Skin Elasticity in Lymphedema Patients N/A Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 2000
NCT03321617 Suspended Glutamate Reducing Interventions in Schizophrenia Phase 1 Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 50
NCT03389620 Suspended Transforaminal Versus Lateralized Interlaminar Cervical Epidurals Phase 2 Interventional COVID-19 restrictions Anticipated 116
NCT03401931 Withdrawn Artificial Intelligence Use for the Detection of Atrial Fibrillation Drivers Observational [Patient Registry] another design of protocole is submitted for approuval before the start date Actual 0
NCT03444948 Suspended A Clinical Study of EUS-RFA (Endoscopic Ultrasound Guided Radiofrequency Ablation) for Inoperable Pancreatic Ductal Adenocarcinoma Phase 2 Interventional There was a voluntary recall from the Habib EUS RFA device manufacturer, Boston Scientific Anticipated 108
NCT03451708 Suspended OKS for the Treatment of Hemispatial Neglect N/A Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 52
NCT03472326 Terminated Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen Phase 2 Interventional GS-9131 did not meet the targeted antiviral response Actual 21
NCT03574181 Terminated Calibration Study of a Blood Alcohol Level Smart Watch Observational Extensive changes to the watch design would be needed to produce a robust device. Actual 11
NCT03579186 Suspended OKS for Gait Instability N/A Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 20
NCT03713619 Suspended This is a Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS). Phase 3 Interventional COVID-19 Pandemic Anticipated 471
NCT03713632 Suspended Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS) Phase 3 Interventional COVID-19 Pandemic Anticipated 471
NCT03715751 Suspended Adaptive Support Ventilation in Acute Respiratory Distress Syndrome N/A Interventional Enrollment has temporarily paused due to COVID-19 and is expected to resume in the future; This is not a suspension of IRB approval Anticipated 20
NCT03911063 Withdrawn Telemedicine Clinical Trial for Cognitive Behavioral Therapy in Familial Dysautonomia N/A Interventional Personnel unavailable to run the study Actual 0
NCT03915964 Suspended A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis Phase 4 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 2600
NCT03927612 Suspended Virtual Reality to Improve Social Perspective Taking N/A Interventional All study interventions have been discontinued at this time due to COVID-19, but study procedures plan to resume following the removal of COVID-19 restrictions. Anticipated 70
NCT03495713 Suspended Lymphoma RadVax LYMPHOMA: A PHASE II TRIAL OF NIVOLUMAB + LOW DOSE RADIOTHERAPY FOR INCOMPLETE RESPONDERS Phase 2 Interventional Covid-19 Anticipated 25
NCT03593395 Suspended LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study) N/A Interventional Accrual temporarily suspended during COVID-19 pandemic Anticipated 841
NCT03762109 Suspended The Use of Dantrolene to Improve Analgesia in Posterior Lumbar Surgery Phase 2 Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 100
NCT04258345 Withdrawn Artificially Sweetened Beverage Feeding Study N/A Interventional not yet funded Actual 0
NCT01280994 Suspended Hyperpolarized 129Xe MRI for Imaging Pulmonary Function Phase 1 Interventional COVID-19 Anticipated 445
NCT02014415 Suspended Alpha-1 Antitrypsin Deficiency Adult Liver Study Observational [Patient Registry] Study visits suspended due to COVID-19 pandemic. Anticipated 120
NCT04362306 Suspended Radiation Oncology Patient Medical Physics Intervention Study N/A Interventional Temporarily suspended due to pandemic Anticipated 66
NCT02478255 Suspended Longitudinal MR Imaging of Pulmonary Function in Patients Receiving Thoracic Radiation Treatment Phase 1 Interventional COVID-19 Anticipated 35
NCT02478268 Suspended Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis Phase 1 Interventional COVID-19 Anticipated 79
NCT02485366 Withdrawn Rejuvenated, Washed Packed Red Blood Cells in Pediatric Cardiac Surgery Phase 4 Interventional Product unavailability Actual 0
NCT02554383 Suspended Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit? Phase 3 Interventional In response to COVID-19. Anticipated 688
NCT02582957 Suspended Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome N/A Interventional All sites suspended because of the COVID pandemic. Anticipated 544
NCT02768727 Suspended A Test of Neural Inertia in Humans With Xenon Phase 2 Interventional Suspended due to COVID-19 Anticipated 24
NCT03143543 Terminated Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use Disorder Phase 1 Interventional FDA removal of drug from the market due to cancer risks Actual 171
NCT03182049 Withdrawn Natural History of Granulomatosis With Polyangiitis: Clinical and Genetic Biomarkers of Airway Disease NoAAC PR-03 Study Observational Funding was not able to be secured for the study and no participants enrolled. Actual 0
NCT03204916 Suspended Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic Leukemia Observational Planned evaluation of patients currently enrolled on study Anticipated 375
NCT03514511 Suspended Safety and Tolerability of LEO 138559 in Healthy Subjects and Subjects With Atopic Dermatitis Phase 1 Interventional Trial put on hold due to COVID 19 pandemic. This is a first-in-human trial and safety information about the investigational medicinal product is limited. Anticipated 54
NCT03548168 Suspended Innovative Imaging of Cerebrum and Muscle (iCAM) Repeatability Study Observational Temporarily stopped due to COVID-19 and expected to resume. Anticipated 32
NCT03571386 Suspended Mechanisms of Mindfulness-based Interventions Observational COVID-19 pandemic Anticipated 98
NCT03802630 Suspended Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion Phase 3 Interventional Only recruitment temporarily paused due to COVID-19 and safety measure Anticipated 500
NCT03810313 Suspended Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion Phase 3 Interventional Only recruitment temporarily paused due to COVID-19 and safety measure Anticipated 750
NCT03898427 Suspended Scratch Behavior Under Standard of Care Observational Currently suspended due to Covid-19 policies. Anticipated 120
NCT03973970 Suspended Assessing the Ability of the T-SPOT®.TB Test (IQ) Observational Enrollment into this study is on hold due to Covid19 Anticipated 202
NCT03978572 Suspended Dual-benefits of Aerobic and Resistance Training N/A Interventional Temporarily paused due to COVID-19 and expected to resume. Not of IRB approval Anticipated 30
NCT04005352 Suspended Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON) Phase 3 Interventional Only recruitment temporarily paused due to COVID-19 and safety measure Anticipated 692
NCT04031885 Suspended A Study of Abemaciclib (LY2835219) in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer Phase 4 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 300
NCT04046991 Suspended Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS Phase 2 Interventional Suspended due to COVID-19 Anticipated 66
NCT04047472 Suspended Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Chinese Patients With Neovascular Age-Related Macular Degeneration Phase 3 Interventional Only recruitment temporarily paused due to safety measures Anticipated 494
NCT04048668 Suspended tDCS to Treat Subacute Aphasia N/A Interventional Suspended due to COVID-19 Anticipated 30
NCT04058067 Suspended To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema Phase 3 Interventional Only recruitment temporarily paused due to safety measures Anticipated 268
NCT04117724 Suspended Antibiotic Adherence Practices in Dermatologic Surgery Observational Suspended due to COVID-19 Actual 160
NCT04127942 Withdrawn Platelet-rich Plasma Injection for Temporomandibular Disorders N/A Interventional no sufficient enrolled pateints Actual 0
NCT04141982 Suspended Clinical Concordance Evaluation of T-SPOT®.TB Assay Performance (T-Cell SelectTM Study) Observational enrollment at NECCR is on hold due to Covid 19. The other sites have completed enrollment Anticipated 700
NCT04149379 Withdrawn Hyperbaric Oxygen Therapy After Stroke - PILOT Phase 2 Interventional Because of the economic consequences of the COVID-19 pandemic 2020 Actual 0
NCT04150523 Suspended Perspectives on Prophylactic Antibiotic Use in Dermatologic Surgery Observational Suspended due to COVID-19 Anticipated 2000
NCT04159701 Suspended A Study of LY3454738 in Adults With Chronic Spontaneous Urticaria Phase 2 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 60
NCT04176653 Withdrawn Study in Beta-thalassaemia or Myelodysplastic Syndrome Patients to Investigate the Safety and Tolerability of SLN124 Phase 1 Interventional Study stopped prior to subject administered first dose, due to COVID-19 Actual 0
NCT04234724 Suspended Physiological Effects of ANGPTL3 Variants in Humans N/A Interventional Suspended due to COVID-19 Anticipated 50
NCT04269824 Suspended The Norms and Networks Sanitation Study in India in Tamil Nadu, India N/A Interventional Suspended due to COVID-19 restrictions Actual 22763
NCT02135679 Suspended The Detection Of Circulating Tumor Cells (CTC) In Patients With NSCLC Undergoing Definitive Radiotherapy Or Chemoradiotherapy Observational Covid-19 Anticipated 160
NCT04277325 Suspended Efficacy of Emotionally Focused Therapy Among Spanish Speaking Couples N/A Interventional The study has been postponed due to mobility constrains during covid-19 crisis. Anticipated 70
NCT04302831 Suspended Restoring Central Motor Control Extension N/A Interventional COVID-19 safety restrictions Anticipated 20
NCT02246738 Suspended Initial Evaluation of a Telomerase-based Circulating Tumor Cell Assay in Bladder Cancer Cohorts Observational Covid-19 Actual 87
NCT02404415 Suspended The Vanderbilt Atrial Fibrillation Ablation Registry Observational [Patient Registry] Anticipated 3000
NCT02452775 Terminated Autologous OC-L Vaccine and Ovarian Cancer Phase 1 Interventional Actual 3
NCT01736267 Terminated Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects N/A Interventional Closed by IRB Actual 3
NCT02943668 Terminated Deferasirox in Treating Patients With Very Low, Low, or Intermediate-Risk Red Blood Cell Transfusion Dependent Anemia or Myelodysplastic Syndrome Phase 2 Interventional Terminated due to low accrual Actual 2
NCT02953548 Terminated Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms (GWPCARE7) Phase 3 Interventional This study met No Go Criteria; all participants enrolled demonstrated continued hypsarrhythmia and spasms on follow-up video EEG after 2 weeks of treatment. Actual 9
NCT03151642 Suspended A PILOT STUDY OF DIFFUSION WEIGHTED MRI TO ASSESS ESOPHAGEAL TUMOR RESONSE TO NEOADJUVANT CHEMORADIATION Observational Covid-19 Anticipated 40
NCT03484923 Suspended Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma Phase 2 Interventional only recruitment temporarily paused due to COVID-19 Anticipated 230
NCT03546829 Suspended Randomized Pilot Trial of Antimicrobial Therapy and Stereotactic Body Radiation Therapy in Early-stage Non-small Cell Lung Cancer Early Phase 1 Interventional Covid-19 Anticipated 40
NCT03559049 Suspended Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer Phase 1/Phase 2 Interventional Enrollment temporarily paused for planned interim analysis; this is not a suspension of IRB approval Anticipated 55
NCT03591770 Suspended Shingrix Vaccine in Patients With Moderate to Severe Ulcerative Colitis on Tofacitinib Phase 4 Interventional Currently suspended due to Covid-19 policies. Anticipated 100
NCT03602066 Suspended Study Evaluating The Role of ClO2 on Mucositis for Pt. Undergoing Head/Neck Radiotherapy Phase 2 Interventional per Pharma company Anticipated 20
NCT03637998 Suspended Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain N/A Interventional Due to COVID-19 Anticipated 40
NCT03649659 Suspended Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions Phase 3 Interventional Enrollment and interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 1060
NCT03652909 Suspended Personal Sound Amplification Device Observational We are not seeing research patients currently due to COVID-19. Anticipated 33
NCT03688919 Suspended Adolescent Interventions to Manage Self-regulation of T1D (AIMS T1D) N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 94
NCT03791060 Suspended Secukinumab for NLD (Cosentyx) in Patients With Necrobiosis Lipoidica Diabeticorum (NLD) Phase 2 Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 18
NCT03857308 Terminated Eudaimonia and Sleep: Effects of a Mindfulness Intervention in Caregivers of People With Dementia N/A Interventional Unable to continue enrollment for dissertation study due to COVID-19 Actual 9
NCT03878459 Suspended Dapagliflozin Plus Pioglitazone in T1DM Phase 4 Interventional Temporary suspension by PI due to Covid-19 Anticipated 120
NCT03913078 Suspended Comparative Effectiveness of Social Physical Play and Traditional Exercise Programming Phase 3 Interventional Temporarily suspended due to Pandemic Anticipated 360
NCT03971149 Suspended EMPOWER Study, a Personalized Home Care Intervention for Older Heart Failure Patients N/A Interventional We came across unexpected difficulty with recruitment that has not been solved. Anticipated 25
NCT03996967 Suspended Diagnostic and Prognostic Biomarkers for Childhood Bacterial Pneumonia Observational Currently suspended due to Covid-19 policies. Anticipated 900
NCT04097834 Suspended Integrating PrEP Into Family Planning Services at Title X Clinics in the Southeastern US Observational Recruitment has been suspended due to COVID-19. Anticipated 300
NCT04175106 Suspended Evaluating the Availability of Berry Phytonutrients Post-consumption of Fresh and Processed Blueberry by Healthy Adults N/A Interventional COVID-2019 Anticipated 28
NCT04181203 Suspended Combined Apalutamide, Radiotherapy, and LHRH Agonist in Prostate Cancer Patients After Prostatectomy Phase 3 Interventional Temporary suspension since March 20 due to COVID-19 pandemic Anticipated 490
NCT04183634 Terminated An Open, Randomised, Single Dose, 2-period, 2-sequence Crossover Adhesion Study of Two Different Transdermal Patches Containing Rotigotine. Phase 1 Interventional Company Decision Actual 31
NCT04246606 Suspended Concordance of the IHC4 Score Performed in Local or Central Laboratory to Endopredict in ER+/HER2- Breast Cancer Observational Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 155
NCT04360967 Withdrawn SURF, Neurodevelopment, Growth Study in SGA Infants N/A Interventional Sponsor decision stopped in June 2017 Actual 0
NCT03197090 Terminated Handheld ECG Tracking of In-hOspital Atrial Fibrillation N/A Interventional poor patient recruitment and limited resources Actual 804
NCT01352429 Suspended Mild Hypofractionation With Proton Therapy or Intensity Modulated Radiation Therapy (IMRT) for Intermediate-Risk Prostate Cancer Observational Covid-19 Anticipated 200
NCT01952223 Suspended A Phase III of Cabazitaxel and Pelvic Radiotherapy in Localized Prostate Cancer and High-risk Features of Relapse Phase 3 Interventional Temporary suspension since March 20 due to COVID-19 pandemic Anticipated 1048
NCT02153229 Suspended Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma Phase 2 Interventional Covid-19 Anticipated 102
NCT02207465 Suspended A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer Phase 1 Interventional Covid-19 Anticipated 42
NCT02343549 Suspended A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM) Phase 2 Interventional accrual temporarily suspended during COVID-19 pandemic Anticipated 46
NCT02507011 Terminated Beta-blockers in Pulmonary Arterial Hypertension Phase 2 Interventional Recruitment Actual 4
NCT02591134 Suspended EffectS of Non-nutritive sWeetened Beverages on appetITe During aCtive weigHt Loss N/A Interventional In response to COVID-19 Anticipated 432
NCT02601833 Suspended Effectiveness of Silver Diamine Fluoride as a Treatment for Caries in Comparison to Traditional Restorative Techniques Phase 3 Interventional Intervention/interactions are temporarily paused due to COVID-19 and are expected to resume. This is not a suspension of IRB approval. Actual 98
NCT02698293 Suspended PDT Plus Vitamin D3 for Anal Dysplasia Phase 1 Interventional Covid-19 Anticipated 12
NCT02805595 Suspended Effect of Sclerotherapy on Fistulas and Sinus Tracts in Hidradenitis Suppurativa Phase 3 Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 20
NCT02836067 Suspended Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 120
NCT02840877 Suspended The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 438
NCT02927847 Suspended Neuroimaging Reward, Behavioral Treatment, and Smoking Cessation Phase 1/Phase 2 Interventional New enrollment is temporarily suspended due to COVID19 restrictions Anticipated 100
NCT02976038 Terminated Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM) Phase 2 Interventional Registration trial did not meet the primary end points Actual 36
NCT03055884 Suspended Investigating Accelerated Learning in Healthy Subjects N/A Interventional low numbers of participants Anticipated 40
NCT03090711 Suspended Sleep as a Model to Understand and Manipulate Cortical Activity in Order to Promote Functional Recovery After Stroke N/A Interventional temporary interruption due to COVID-19 - participants belong to the risk group Anticipated 60
NCT03143842 Suspended Investigating Accelerated Learning in Tinnitus Participants Implanted With Vagus Nerve Stimulation N/A Interventional Not enough participants Anticipated 6
NCT03173794 Withdrawn CommunityRx for Hunger: A Hospital-Based Intervention N/A Interventional This trial was a duplicate entry. Recruitment was never open and no participants were enrolled. Actual 0
NCT03274440 Suspended Effects of Marijuana on Symptoms of OCD Phase 1/Phase 2 Interventional Principle Investigator was deployed to NYP to help with COVID-19 response team Actual 14
NCT03276741 Terminated Oral Intake During Labor N/A Interventional Unable to recruit to enrollment target Actual 126
NCT03301909 Suspended Development of Applications of PillCam™ Endoscopy and Patency Systems and Clinical Evaluation of Their Performance in Healthy Volunteers ("HEIGHT" Study) N/A Interventional COVID-19 Anticipated 1000
NCT03323749 Terminated A Trial to Evaluate the Safety and Efficacy of Elamipretide in Subjects With Primary Mitochondrial Myopathy Followed by an Open-Label Extension Phase 3 Interventional Part1,double blind portion of the trial did not meet the primary end points Actual 218
NCT03363711 Suspended AYA STEPS RCT: AYA Self-Management Via Texting, Education & Plans for Survivors Observational Covid-19 Actual 25
NCT03406923 Suspended Self-efficacy, Beliefs and Adherence- Pilot and Feasibility Trial of a Pharmacist-led Intervention N/A Interventional due to COVID-19 Anticipated 50
NCT03485365 Suspended A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement Study in Healthy Volunteers and Subjects With Osteoarthritis (OA) Phase 1 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 98
NCT03510988 Suspended Dedicated Breast PET/MRI in Evaluation of Extent of Disease in Women With Newly Diagnosed Breast Cancer N/A Interventional Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 147
NCT03559309 Terminated Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia Phase 4 Interventional COVID-19 Pandemic Measures Actual 24
NCT03276975 Suspended A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment Phase 2 Interventional COVID-19 restrictions Anticipated 200
NCT03653741 Suspended Effects of Perampanel on Neurophysiology Test Perimeters Phase 4 Interventional The study is temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 12
NCT03726671 Suspended Choline Nutritional Status: Development of a Biomarker Panel N/A Interventional Subject activity suspended due to COVID-19. Recruiting - respond to emails only. Anticipated 180
NCT03731598 Withdrawn Ceramides in Muscle During Insulin Resistance Observational Difficulty recruiting. Objectives from this protocol added to another protocol collecting the same information. Actual 0
NCT03790072 Suspended Ex-vivo Expanded γδ T-lymphocytes (OmnImmune®) in Patients With Acute Myeloid Leukaemia (AML) Phase 1 Interventional Suspended due to COVID-19 situation Anticipated 9
NCT03414411 Suspended Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study Observational Enrollment temporarily suspended due to covid-19 policies. Anticipated 400
NCT03994185 Withdrawn The Merit WRAPSODY™ Endovascular Stent Graft for Treatment of Iliac Artery Occlusive Disease N/A Interventional Study was withdrawn by the Sponsor prior to enrollment Actual 0
NCT04065841 Suspended Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin Compared to Each Monotherapy, in Adult Patients With NASH and Liver Fibrosis Phase 2 Interventional COVID-19 Pandemic Anticipated 210
NCT04069702 Suspended Virtual Reality for Improving Pain and Distress in Patients With Advanced Stage Colorectal Cancer N/A Interventional COVID-19 restrictions on in person activities for non-essential studies Anticipated 20
NCT03695042 Suspended Blood Flow Restriction Concussion N/A Interventional Covid-19 Anticipated 10
NCT04119024 Suspended Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma Phase 1 Interventional SAE review Anticipated 24
NCT03750643 Suspended A Study of LY3454738 in Healthy Participants and Participants With Atopic Dermatitis Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 128
NCT03764774 Suspended A Study of LY3463251 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 143
NCT03770494 Suspended A Study of LY3405105 in Participants With Advanced Cancer Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 215
NCT04214184 Suspended Biomarkers of Increased Free Living Sleep Time N/A Interventional On hold due to COVID-19 outbreak Anticipated 46
NCT03844412 Suspended Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments Phase 2 Interventional Enrollment of new participants is suspended until activities return to normal following Covid-19 resolution. Anticipated 400
NCT04273867 Suspended Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis Observational Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 60
NCT03856359 Suspended Trial of Rifaximin in Probable Alzheimer's Disease Phase 2 Interventional Study suspended due to the Covid19 virus until further notice Anticipated 10
NCT03861923 Suspended Dry Needling for Shoulder Adhesive Capsulitis N/A Interventional Covid-19 Measures Anticipated 100
NCT03929744 Suspended A Study of LY3502970 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 160
NCT03933943 Suspended A Study of LY3361237 in Participants With Systemic Lupus Erythematosus Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 24
NCT03949842 Withdrawn Legend: TRELEGY Real World Chronic Obstructive Pulmonary Disease (COPD) Effectiveness Study Phase 4 Interventional The decision to end the study was based on a change in GSK strategy. No subjects were enrolled into the study. Actual 0
NCT03951753 Suspended A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus (T2DM) Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 117
NCT03977974 Terminated A Study of LY3526318 in Healthy Participants Phase 1 Interventional COVID-19 pandemic. Actual 76
NCT01094691 Suspended Haufen Diagnostic Biomarkers of BK Renal Disease N/A Interventional Temporary suspension of recruitment and research activities due to COVID-19 Anticipated 10
NCT04119557 Suspended A Study of LY3471851 in Participants With Psoriasis Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 40
NCT04148937 Suspended A Study of the CD73 Inhibitor LY3475070 Alone or in Combination With Pembrolizumab in Participants With Advanced Cancer Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 120
NCT02257879 Withdrawn DHB Supplement Interaction Study Observational due to constraints with collaborator and subject matter expert, recruitment was unable to begin Actual 0
NCT04152382 Suspended A Safety Study of LY3462817 in Participants With Psoriasis Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 64
NCT04165031 Suspended A Study of LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation Phase 1/Phase 2 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 230
NCT02604667 Suspended Mechanisms of Ischemic Stroke in Cancer Patients Observational Study paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 165
NCT04230122 Suspended A Study of LY3478006 in Healthy Participants Phase 1 Interventional Protocol stopping criteria (safety) were met. Anticipated 56
NCT04266756 Suspended A Study of Selexipag in Healthy Male Participant Phase 1 Interventional Due to strict measures of the government to contain the spread of COVID-19 outbreak, we follow the recommendation of the Ethics Committee to suspend this trial. Anticipated 24
NCT04270370 Suspended A Study of LY3478045 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 90
NCT04329572 Suspended Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Hospitalized Patients With Moderate to Severe COVID-19 Early Phase 1 Interventional Azidus, the CRO hired for this study by Prevent Senior has lost the interest to conduct this study. Anticipated 400
NCT04348474 Suspended Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Ambulatory Patients With Mild COVID-19 Early Phase 1 Interventional Azidus, the CRO hired for this study by Prevent Senior has lost the interest to conduct this study. Anticipated 200
NCT04357704 Withdrawn Improved Speech Recognition Performance in Noise by Encoding Binaural Spatial Cues to the Cochlea Implant User N/A Interventional Delay in setting up the study. Actual 0
NCT02963766 Suspended A Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes Phase 3 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 150
NCT02115464 Terminated Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy Phase 2 Interventional The accrual rate was not high enough to reach the target sample size. Actual 54
NCT03170258 Suspended Self-activation in Individuals With and Without Nicotine Dependence N/A Interventional temporarily suspended due to COVID-19 Anticipated 100
NCT03246347 Suspended A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer Phase 2 Interventional accrual temporarily suspended during COVID-19 pandemic Anticipated 39
NCT02693743 Terminated Repetitive Transcranial Magnetic Stimulation as Treatment for Acute Suicidality in Adult Patients N/A Interventional Study terminated early due to slow accrual or other non-safety related issues Actual 1
NCT02775760 Suspended The Entorhinal Cortex and Aerobic Exercise in Aging N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 42
NCT02991456 Suspended Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide Phase 2 Interventional COVID-19 restrictions Anticipated 160
NCT03064490 Suspended Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago-gastric Diseases (PROCEED) Phase 2 Interventional COVID-19 Anticipated 38
NCT03071328 Suspended INJECT: A Pilot Study of Intra-tumoral Injections in Metastatic Urological Cancers Early Phase 1 Interventional Study deemed non-essential under COVID pandemic Anticipated 15
NCT03169075 Suspended QUALIOR Feasibility and Efficacy of a Supervised Home-based Standard Physical Exercise Program N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 312
NCT03203239 Suspended Red Light Treatment in Peripheral Artery Disease N/A Interventional COVID-19 Anticipated 40
NCT03228186 Suspended Trial of Pevonedistat Plus Docetaxel in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 37
NCT03250468 Terminated Sleep to Your Heart's Content - Insomnia Intervention for Cardiac Patients N/A Interventional Poor follow/up rates and data. Actual 52
NCT03267381 Suspended Circulating Blood Profile to Predict Recurrence and Response to Systemic Therapy Observational Pause for COVID 19 response Anticipated 30
NCT03273335 Suspended Investigating NeuroinflammaTion UnderlyIng Postoperative Brain Connectivity Changes, POCD, Delirium in Older Adults Observational COVID-19 social distancing requirements Anticipated 200
NCT03283631 Suspended Intracerebral EGFR-vIII CAR-T Cells for Recurrent GBM Phase 1 Interventional We are temporally halting enrollment until a protocol amendment is approved. Anticipated 24
NCT03297697 Suspended Minimal Residual Disease in Peripheral T-cell Lymphoma Observational COVID-19 Anticipated 42
NCT03327805 Suspended Short Term Choline and Cardiovascular Health N/A Interventional COVID-19 restrictions Anticipated 34
NCT03333356 Suspended Adjuvant Radiotherapy in Patients With Pathological High-risk Bladder Cancer (GETUG-AFU 30) N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 109
NCT03402607 Suspended Trial Comparing PLA to HIGRT Therapy (PROVE-HCC) Phase 2 Interventional COVID-19 Anticipated 90
NCT03417570 Suspended Cap Assisted Upper Endoscopy Versus High Definition White Light Endoscopy and Narrow Band Imaging Alone In The Detection Of Visible Lesions Barrett's Esophagus: A Randomized Tandem Study N/A Interventional COVID-19 Anticipated 170
NCT03423407 Suspended Evaluation of Attenuation Correction Accuracy in Positron Emission Tomography-Magnetic Resonance Imaging (PET-MRI) Observational COVID-19 Anticipated 60
NCT03436433 Suspended Seizure Prophylaxis Study Phase 2 Interventional COVID-19 restrictions Anticipated 232
NCT03516708 Suspended Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer Phase 1 Interventional COVID-19 Anticipated 39
NCT03523975 Suspended Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma Phase 1 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 28
NCT03578965 Suspended Does Antibiotic Prophylaxis Reduce Wound Complications After Vulvar Excision of Premalignant Lesions Phase 2 Interventional COVID-19 Anticipated 50
NCT03601819 Suspended Pacritinib in Relapsed/Refractory Lymphoproliferative Disorders Phase 1 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 26
NCT03617224 Withdrawn Pembrolizumab and Total Skin Electron Beam Radiotherapy in Mycosis Fungoides and Sézary Syndrome Phase 1 Interventional Unable to enroll patients that met enrollment criteria. Actual 0
NCT03617484 Suspended Bortezomib in Combination With Ibrutinib in Ibrutinib Relapsed Mantle Cell Lymphoma Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 35
NCT03687957 Suspended rhIL-7-hyFc on Increasing Lymphocyte Counts in Patients With Newly Diagnosed Non-lymphopenic Gliomas Following Radiation and Temzolomide Phase 1/Phase 2 Interventional COVID-19 Anticipated 46
NCT03697850 Suspended Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 77
NCT03707158 Suspended Kids FACE FEARS Comparative Effectiveness Research N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 1856
NCT04211350 Suspended SLEEP ON Your SIDE (SOS) Study N/A Interventional COVID-19 Anticipated 150
NCT03802396 Suspended Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction Phase 2 Interventional COVID-19 social distancing requirements Anticipated 201
NCT03809455 Withdrawn Effectiveness and Tolerance of Fentanyl Citrate in Painful Pain Induced During Diagnostic or Therapeutic Examinations in Cancer Patients Phase 2 Interventional Study was cancelled by Sponsor. Actual 0
NCT03841058 Suspended Phase II Trial of Abaloparatide vs. Placebo in Post-Menopausal Women Receiving Initial Spinal Fusion Surgery Phase 2 Interventional Due to COVID-19. Anticipated 72
NCT03851237 Suspended CCR2 PET for Pancreatic Cancer Imaging and Prediction of Response to Standard and CCR2-Targeted Therapy Phase 1 Interventional COVID-19 Anticipated 75
NCT03560960 Suspended Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease Early Phase 1 Interventional Currently suspended due to Covid-19 policies. Anticipated 240
NCT03916419 Suspended Magnetic Resonance-Guided Hypofractionated Adaptive Radiation Therapy With Concurrent Chemotherapy and Consolidation Durvalumab for Inoperable Stage IIB and IIIA Non-small Cell Lung Cancer Phase 2 Interventional COVID-19 Anticipated 27
NCT03928379 Suspended A Study of LY3305677 in Participants With Type 2 Diabetes Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 48
NCT03940742 Suspended A Study of Tirzepatide in Participants With Impaired Liver Function Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 42
NCT03964337 Suspended Immediate Prostatectomy vs. Cabozantinib Followed by Prostatectomy in Men With High-Risk Prostate Cancer Phase 2 Interventional Enrollment is suspended due to COVID-19. Anticipated 33
NCT00615784 Terminated Phase II Study of Bexarotene in Patients With Acute Myeloid Leukemia Phase 2 Interventional Study terminated. Eisai's Targretin acquired by another pharmaceutical company. Actual 25
NCT04014361 Suspended A Study of LY3154885 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 102
NCT04019054 Terminated TMS and Exposure Therapy N/A Interventional COVID Actual 17
NCT04047446 Suspended Liposomal Bupivacaine vs Dexamethasone ISB Phase 4 Interventional response to COVID-19 Anticipated 112
NCT04050553 Suspended A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 38
NCT04052594 Suspended A Study of LY3475766 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 55
NCT04081350 Suspended A Study of LY3471851 in Participants With Eczema Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 40
NCT04089865 Suspended Oral Versus IV TXA Phase 4 Interventional response to COVID-19 Anticipated 400
NCT04106206 Suspended A Safety Study of LY3372689 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 54
NCT04115007 Suspended Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients Phase 3 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 350
NCT04126161 Suspended HIP: Hip Imaging Protocol N/A Interventional COVID-19 Restrictions Anticipated 40
NCT00003645 Terminated Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence Phase 3 Interventional Per PI request Actual 64
NCT04143802 Suspended A Study of LY3437943 in Participants With Type 2 Diabetes Mellitus (T2DM) Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 75
NCT04156581 Suspended Erector Spinae Plane Block Versus Conventional Analgesia in Complex Spine Surgery Phase 4 Interventional response to COVID-19 Anticipated 46
NCT04156750 Suspended A Study of LY3556050 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 51
NCT01409811 Terminated Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid N/A Interventional Study closed after it became too difficult to interest patients in participating. Actual 9
NCT04161976 Suspended A Study of LY900027 Given by Insulin Pump to Participants With Type 1 Diabetes Mellitus Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 20
NCT04199598 Terminated Relative Bioavailability Study With Abediterol Administered Via Three Different Inhalation Devices in Healthy Volunteers. Phase 1 Interventional The decision to terminate has been taken by the Sponsor. The decision is not due to safety concerns but reflects business prioritizations of the company. Actual 25
NCT04167072 Withdrawn Observation vs Early Removal of LAMS in EUS Guided Cholecystoenterostomy N/A Interventional Unexpected difficulties recruiting and following patients Actual 0
NCT04172987 Suspended A Study of the Effect of Tirzepatide on How the Body Handles Birth Control Pills in Healthy Female Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 42
NCT04217057 Suspended Imaging CCR2 Receptors With 64Cu-DOTA-ECL1i in Head and Neck Cancer Phase 1 Interventional COVID-19 Anticipated 20
NCT04235309 Suspended Physical Resilience: Indicators and Mechanisms in the Elderly (PRIME) Collaborative Phase 2 Observational COVID-19 social distancing requirements. Anticipated 250
NCT04259346 Suspended A Study of Two Formulations of Ixekizumab in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 216
NCT04276207 Suspended A Study of LY900014 Versus Insulin Lispro (Humalog) on High Blood Sugar in Participants With Type 1 Diabetes Who Use Insulin Pumps Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 28
NCT01750567 Suspended A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 40
NCT01785342 Suspended DECAMP-1: Diagnosis and Surveillance of Indeterminate Pulmonary Nodules Observational Currently suspended due to Covid-19 policies. Anticipated 500
NCT02104921 Suspended Innovative Ultrasound Technology in Neuromuscular Disease Observational COVID-19 Anticipated 240
NCT03378973 Terminated The Effects of Dexmedetomidine Dose on Motor Evoked Potentials Phase 4 Interventional No longer clinically relevant Actual 7
NCT02118805 Suspended Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders Observational COVID-19 Anticipated 200
NCT02300194 Withdrawn Randomized, Double-blind, Placebo, Controlled Cross Over Design Topical Morphine for Analgesia in Pediatric Procedures Phase 4 Interventional Withdrawn by investigators Actual 0
NCT02504697 Suspended DECAMP-2: Screening of Patients With Early Stage Lung Cancer or at High Risk for Developing Lung Cancer Observational Currently suspended due to Covid-19 policies. Anticipated 800
NCT02613598 Suspended Dose Escalation Study to Determine the Maximum Tolerated Dose of the Combination of Ruxolitinib and Bortezomib in Patients With Relapsed or Refractory Lymphoma Phase 1 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 24
NCT02667119 Suspended Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults N/A Interventional due to COVID-19 Anticipated 40
NCT02718391 Terminated Complementary Vaccination With Dendritic Cells Pulsed With Autologous Tumor Lysate in Resected Stage III and IV Melanoma Patients. Phase 2 Interventional The randomization to the observational arm of the trial was no longer ethical Actual 12
NCT02718404 Terminated 3 Tesla Magnetic Resonance Guided High Intensity Focused Ultrasound in the Treatment of Pain From Bone Metastases of Solid Tumors N/A Interventional following the non-renewal of the loan agreement for the medical device Actual 12
NCT02781792 Suspended Temozolomide Chronotherapy for High Grade Glioma Phase 2 Interventional COVID-19 Anticipated 40
NCT02817958 Suspended Evaluation of Lymphadenectomy and Chemotherapy TIP on Inguinal Lymph Nodes in Squamous Cell Carcinoma of the Penis (AFU-GETUG 25) Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 37
NCT02891759 Suspended Compare Outcomes Between Two Acellular Dermal Matrices Phase 2 Interventional COVID-19 Anticipated 400
NCT00300638 Suspended Alcoholism: Emotion and Thinking Observational Currently suspended due to COVID-19 policies. Anticipated 700
NCT02521558 Suspended Effectiveness of Home-based Electronic Cognitive Therapy in Alzheimer's Disease N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 100
NCT02918435 Suspended Implementing an Intervention to Address Social Determinants of Health in Pediatric Practices N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 2520
NCT03062111 Suspended Laser Enucleation of Prostate (LEP) Versus Transurethral Resection of Prostate (TURP) N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 100
NCT03462940 Suspended Effects of TUDCA on Endothelial Function in Type 2 DM N/A Interventional Currently suspended due to covid-19 policies. Anticipated 25
NCT03637296 Suspended Adapting Critical Time Intervention to Support Inpatient Medical Care Transition N/A Interventional This study is temporarily suspended due to COVID-19 pandemic Anticipated 60
NCT03644927 Suspended Exercise Maintenance in Chronic Pain and PTSD N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 70
NCT03929640 Suspended Management Of Pain After Cesarean Trial Phase 3 Interventional Temporarily suspended due to Pandemic Anticipated 144
NCT04247061 Suspended Usability Study of a Smoking Cessation Intervention During a Dental Cleaning N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 15
NCT03430531 Suspended Effectiveness of Sphenopalatine Ganglion Block for Post-Dural Puncture Headache Phase 2 Interventional Temporarily suspended due to Pandemic Anticipated 30
NCT03507374 Terminated PCSK9 Inhibition in Patients With Symptomatic Intracranial Atherosclerosis Early Phase 1 Interventional Funding withdrawn Actual 20
NCT03576976 Suspended Improving Accessibility and Personalization of CR for Schizophrenia N/A Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 100
NCT03637842 Suspended Lorcaserin for Cannabis Use Disorder Early Phase 1 Interventional suspended due to lorcaserin recall Anticipated 90
NCT03711500 Suspended D-serine Augmentation of Neuroplasticity Phase 1/Phase 2 Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 45
NCT03739840 Suspended A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 500
NCT03740139 Suspended The Police-Mental Health Linkage System N/A Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 1600
NCT03817528 Suspended ITI-007 (Lumateperone Tosylate) for Schizophrenia Phase 2 Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 40
NCT03895203 Suspended A Study to Test the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 840
NCT03896581 Suspended A Study to Evaluate the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 390
NCT03928743 Suspended A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 300
NCT03971422 Suspended A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 240
NCT04039919 Suspended A Study to Test the Pharmacodynamic, Pharmacokinetic, Safety, and Tolerability of Padsevonil in Healthy Study Participants Receiving Either Ethanol or Cannabidiol Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 44
NCT04200456 Suspended A Study to Evaluate the Efficacy, Safety, and Tolerability of Rozanolixizumab in Adult Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP) Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 105
NCT04242446 Suspended A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 490
NCT04242498 Suspended A Study to Test the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 490
NCT04283136 Suspended A Study to Test the Blood Concentration of 4 Padsevonil Product Variants and the Effect of Food on Padsevonil Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 46
NCT04335578 Suspended A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of UCB7858 in Adult Kidney Transplant Recipients With Chronic Allograft Injury Phase 1/Phase 2 Interventional Study recruitment temporarily halted as a precautionary measure due to COVID-19 pandemic Actual 1
NCT01376752 Suspended Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) in Relapse Ovarian Cancer Treatment Phase 3 Interventional Temporary suspension since March 20th 2020 due to COVID-19 pandemic Anticipated 444
NCT01829386 Suspended Non-Heme Iron Load Quantification in the Brain - MRI of Patients With Stroke Observational Enrollment is temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 10
NCT01905397 Suspended Negative Pressure Wound Therapy to Reduce Surgical Site Infection N/A Interventional COVID-19 - Pending approval to re-open study and add additional subjects Anticipated 135
NCT02229565 Suspended Molecular Mechanisms Underlying Prostate Cancer Disparities N/A Interventional Study deemed non-essential under COVID pandemic. Anticipated 198
NCT02553525 Suspended Effects of Stimulation Patterns of Deep Brain Stimulation N/A Interventional temporarily suspended due to COVID-19 social distancing measures Anticipated 180
NCT02834065 Suspended Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest N/A Interventional Enrollment suspended during the COVID-19 pandemic Anticipated 273
NCT02933671 Suspended Suprainguinal Fascia Iliaca (SIFI) Block Improves Analgesia Following Total Hip Arthroplasty Phase 4 Interventional COVID -19 HOLD Anticipated 40
NCT02967289 Suspended IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting Phase 3 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 640
NCT02980510 Suspended Comparison FOLFIRINOX Panitumumab vs mFOLFOX6 Panitumumab in RAS/B-RAF Wild-type Metastatic Colorectal Cancer Patients Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 209
NCT03025087 Suspended Hydroxychloroquine and Cognitive Function After Surgery Phase 4 Interventional Recruitment suspending during the COVID-19 pandemic. Anticipated 30
NCT03081052 Suspended Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes Phase 4 Interventional Enrollment suspended during the COVID-19 pandemic Anticipated 424
NCT03164655 Suspended Improving SUrgery of Liver Metastases: a Trial of the Arterial Chemotherapy Network Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 140
NCT03268304 Withdrawn Feasibility of Two New Software Modules for the Rehabilitation of Patients With Neuromuscular Upper Limb Impairments Observational The software modules were not completed. Actual 0
NCT03353233 Suspended Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty. Phase 4 Interventional COVID-19 HOLD Anticipated 38
NCT03371173 Terminated ORal IrON Supplementation With Ferric Maltol in Patients With Pulmonary Hypertension (ORION-PH-1) Phase 3 Interventional low recruitment rate; difficulties to achieve planned number of participants within reasonable time frame Actual 22
NCT03403465 Suspended Intratreatment FDG-PET During Radiation Therapy for Gynecologic and Gastrointestinal Cancers Phase 2 Interventional COVID-19 restrictions Anticipated 130
NCT03513302 Suspended Dietary Nitrate and Muscle Power With Aging Phase 1 Interventional COVID-19 pandemic Anticipated 20
NCT03533985 Suspended Effect of Music Therapy on Infants With Neonatal Abstinence Syndrome N/A Interventional COVID-19 Anticipated 200
NCT03595774 Suspended Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals Phase 1 Interventional COVID-19 pandemic Anticipated 10
NCT03628560 Suspended Alternate Methodology of Pulse Oximeter Validation N/A Interventional COVID-19 HOLD Anticipated 30
NCT03695172 Suspended Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section Phase 4 Interventional Suspended due to COVID-19 Anticipated 75
NCT03928704 Suspended A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Nonradiographic Axial Spondyloarthritis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 240
NCT03726268 Suspended Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement) Phase 4 Interventional COVID-19 HOLD Anticipated 1000
NCT03774615 Terminated ORal IrON Supplementation With Ferric Maltol in Patients With Heart Failure Carrying Left Ventricular Assist Devices Phase 4 Interventional low recruitment rate; difficulties to achieve planned number of participants within reasonable time frame Actual 11
NCT03777813 Suspended Association of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 120
NCT03807518 Suspended Pre- and Post-Operative Exercise Program in Upper Gastrointestinal Cancers N/A Interventional Suspended due to COVID-19 Anticipated 64
NCT03815656 Suspended Closed Loop DBS Implanted RC+S Study N/A Interventional temporarily suspended due to COVID-19 social distancing measures Anticipated 6
NCT03827291 Suspended QL Block With Exparel in Colectomy Phase 4 Interventional COVID-19 Hold Anticipated 30
NCT03839082 Suspended Structured Mobile Technology Based Lifestyle Program vs Usual Care for Patients With Non-alcoholic Fatty Liver Disease N/A Interventional Enrollment and interactions/interventions are temporarily paused due to COVID-19 and are expected to resume. This is not a suspension of IRB approval. Anticipated 120
NCT03863639 Suspended Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia Observational Enrollment hold Anticipated 30
NCT03928808 Suspended Fecal Microbiota Transplantation (FMT) in Treatment of Severe and Enduring Anorexia Nervosa Early Phase 1 Interventional Currently on partial clinical hold due to COVID-19 policies. Anticipated 10
NCT03943667 Suspended Gemcitabine and Paclitaxel vs Gemcitabine Alone After FOLFIRINOX Failure in Metastatic Pancreatic Ductal Adenocarcinoma Phase 3 Interventional Temporary suspension since March 20th, 2020 due to COVID-19 pandemic Anticipated 210
NCT03958552 Suspended Palliative Care Consultations in the Skilled Nursing Facility (SNF) Setting N/A Interventional Suspended do to COVID-19 Anticipated 160
NCT03962348 Suspended Reducing DUP Through Early Detection in a Large Jail System N/A Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 20
NCT03995238 Suspended Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation N/A Interventional Temporarily supended due to COVID-19 Anticipated 54
NCT04095442 Suspended Effect of Antibacterial Mouthwash on Muscle Function in Healthy Young Men and Women Early Phase 1 Interventional COVID-19 pandemic Anticipated 16
NCT04136444 Suspended A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 24
NCT04158362 Suspended Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer Phase 3 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 378
NCT04163016 Suspended A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 20
NCT04255862 Suspended A Study to Evaluate the Bioequivalence of Bimekizumab Given as 1x2mL or 2x1mL Subcutaneous Injection in Healthy Study Participants Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 400
NCT04270045 Suspended Forced Oscillometry in Infants With Bronchopulmonary Dysplasia Observational Suspended per institutional directive due to COVID-19 Pandemic; No suspension of IRB approval Anticipated 20
NCT04278872 Suspended Phase 2 Study of SJX-653 in Postmenopausal Women With Moderate to Severe Vasomotor Symptoms Phase 2 Interventional Temporarily halted due to COVID-19 Anticipated 130
NCT01803906 Suspended Tissue Sample Study for Mitochondrial Disorders Observational Recruitment on hold Anticipated 6900
NCT01913327 Terminated Antipsychotic Effects on Brain Function in Schizophrenia Phase 4 Interventional Insufficient Funds and Inadequate Subject Recruitment Actual 4
NCT02316574 Suspended The Role of Neural Systems for Emotion Regulation in Coping With Alcohol Craving N/A Interventional This study is temporarily suspended due to COVID-19 pandemic Anticipated 40
NCT03405714 Suspended A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Intravenous Brivaracetam in Subjects >= 1 Month to < 16 Years of Age With Epilepsy Phase 2 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 50
NCT03457077 Suspended Neural and Mobile Assessment OF Behavior Change Among Problem Drinkers N/A Interventional This study is temporarily suspended due to COVID-19 pandemic Anticipated 150
NCT03496792 Suspended The Venous Distension Reflex and Orthostatic Hypertension N/A Interventional Temporarily suspended due to Pandemic Anticipated 30
NCT03513770 Suspended Autonomic Control of the Circulation and VDR Early Phase 1 Interventional Temporarily suspended due to Pandemic Anticipated 18
NCT03518606 Suspended Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours Phase 1/Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 150
NCT03612960 Suspended Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes Early Phase 1 Interventional Temporarily suspended due to Pandemic Anticipated 90
NCT03649477 Suspended Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome Phase 3 Interventional Enrollment is paused due to COVID-19. This is not a suspension of IRB approval. Anticipated 175
NCT03761030 Suspended L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults Phase 4 Interventional This study is temporarily suspended due to COVID-19 pandemic. Actual 30
NCT03774732 Suspended PD-(L)1 Inhibitors With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer Phase 3 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 510
NCT03812588 Suspended Contact: Developing New Clinical Management Strategies Phase 4 Interventional This study is temporarily suspended due to COVID-19 pandemic. Actual 29
NCT03812614 Suspended Comparative Effectiveness of Family vs. Individually Focused Diabetes Education and Support N/A Interventional Study recruitment is temporarily suspended to maximize the safety of participants and staff due to current concerns about transmission of COVID-19. Anticipated 536
NCT03861481 Suspended A Study to Assess the Efficacy, Safety and Tolerability of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy Phase 2 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 34
NCT03878342 Suspended Radiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 666
NCT03887078 Suspended Noom Coach for Bariatric Health N/A Interventional Covid-19 Anticipated 200
NCT03905928 Suspended Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes N/A Interventional Temporarily suspended due to Pandemic Anticipated 56
NCT03910673 Suspended Intravenous Fosfomycin Pharmacokinetics Study Phase 1 Interventional COVID-19 Anticipated 33
NCT03957525 Terminated Pediatric Preoperative Virtual Reality Program N/A Interventional Recruiting process could not be completed; lack of participants Actual 11
NCT04026776 Suspended Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm Early Phase 1 Interventional COVID19 Anticipated 210
NCT03306849 Suspended Ultrasonographic Evaluation of Anovulatory Disorders in Lean and Overweight Women Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 150
NCT04035200 Suspended Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation Phase 2 Interventional Study recruitment suspended during COVID-19 pandemic Anticipated 150
NCT04044716 Suspended Nurse Initiated Acupressure for Pain Management N/A Interventional COVID 19 Anticipated 52
NCT04051229 Suspended Exercise Training and Metabolic Flexibility in Prediabetes N/A Interventional COVID 19 Anticipated 20
NCT04083053 Suspended High-Resolution Anoscopy Perceived Discomfort Study N/A Interventional COVID 19 Anticipated 54
NCT04084093 Withdrawn Evaluating the Use of a Concentrated Surfactant Gel in Burn Patients N/A Interventional Study will be redesigned. Actual 0
NCT04097717 Suspended My Decision Tubal Sterilization Decision Support Tool N/A Interventional This study has been temporarily suspended due to the COVID-19 pandemic. Anticipated 350
NCT04124939 Suspended Is 10 Injections of Bladder Botox Less Painful Than 20 Injections? Phase 4 Interventional COVID19 Anticipated 40
NCT04126343 Suspended A Study to Test the Cardiac Effects of Padsevonil in Healthy Study Participants Phase 1 Interventional Study temporarily halted as a precautionary measure due to the COVID-19 pandemic Actual 45
NCT04132960 Suspended Study of DS-8201a, an Antibody Drug Conjugate for Advanced Breast Cancer Patients, With Biomarkers Analysis Phase 2 Interventional Temporary suspension since March 19 due to COVID-19 pandemic Anticipated 162
NCT03539835 Suspended Resistance Training to Improve Fatigue and Physical Function in Postmenopausal Breast Cancer Survivors N/A Interventional Study suspended temporarily due to COVID-19 Anticipated 50
NCT04159571 Suspended QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt N/A Interventional COVID 19 Anticipated 138
NCT03547453 Suspended Ovarian Ultrasonography for the Clinical Evaluation of Polycystic Ovary Syndrome Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 240
NCT04180709 Suspended CBT to Reduce Insomnia and Improve Social Recovery in Early Psychosis N/A Interventional All non-COVID-19 NIHR research is suspended due to social distancing measures. Anticipated 44
NCT04302389 Suspended Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program N/A Interventional due to COVID-19 Anticipated 150
NCT03621670 Suspended GlaxoSmithKline's (GSK) Safety and Immunogenicity Study of GSK Meningococcal Group B and 13-valent Pneumococcal Vaccines Administered Together With Routine Infant Vaccines in Healthy Infants Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 1800
NCT04353258 Suspended Research Intervention to Support Healthy Eating and Exercise N/A Interventional due to COVID-19 Anticipated 192
NCT03756285 Suspended Safety and Tolerability Study of AZD4831 in Patients With Heart Failure. Phase 2 Interventional Study put on hold due to Covid-19 situation and for the safety of our study subjects. Anticipated 96
NCT03795350 Terminated Lung Deposition of TRIMBOW® pMDI in Healthy Volunteers, Asthmatic and COPD Patients Phase 1 Interventional In light of the cessation of non-essential clinical activities at CPU due to the COVID-19 pandemic, the sponsor has determined to terminate the study early. Actual 19
NCT04273321 Suspended Efficacy and Safety of Corticosteroids in COVID-19 N/A Interventional The epidemic of COVID-19 in China has been coming to an end. Anticipated 400
NCT00930046 Terminated The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine N/A Interventional The institution transitioned from open surgical procedure to Robotic procedure Actual 15
NCT01785719 Suspended Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss N/A Interventional Suspended due to COVID-19; no suspension of IRB approval. Anticipated 100
NCT01859663 Suspended Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 360
NCT01927432 Suspended Ultrasound Characterization of Ovarian Follicle Dynamics in Women With Amenorrhea Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 80
NCT01927471 Suspended Nutritional and Metabolic Correlates of Ovarian Morphology in Women With Polycystic Ovary Syndrome Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 360
NCT02753283 Suspended Preventing Osteoporosis Using Denosumab Phase 4 Interventional IRB recruitment suspension due to COVID-19 related research restrictions. Anticipated 212
NCT03037580 Terminated Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction Phase 3 Interventional Terminated by sponsor Actual 84
NCT03043651 Terminated Study of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Heart Failure With Preserved Ejection Fraction (HFpEF) Phase 3 Interventional Terminated by sponsor Actual 48
NCT03077776 Suspended Tracking Triple-negative Breast Cancer Evolution Through Therapy N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 250
NCT03143322 Suspended Standard Treatment +/- SBRT in Solid Tumors Patients With Between 1 and 3 Bone-only Metastases N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 196
NCT03279952 Suspended Neurophysiological Markers of Pediatric Irritability and Its Response to Intervention Phase 4 Interventional Temporarily suspended due to Pandemic Anticipated 47
NCT03288389 Suspended Membrane Lipid Replacement in Fibromyalgia N/A Interventional until further notice due to COVID-19 pandemic. Anticipated 60
NCT03297762 Terminated Increasing Use of Continuous Glucose Monitors in Publicly-insured Youth With Type 1 Diabetes N/A Interventional Enrollment challenges Actual 4
NCT03321006 Suspended Treating Hearing Loss to Improve Mood and Cognition in Older Adults Phase 4 Interventional This study is temporarily suspended due to COVID-19 pandemic. Actual 27
NCT03338257 Suspended Husky Reads Effectiveness in Increasing Produce Preference and Food Group Identification in Preschool Children N/A Interventional Covid 19 pandemic Anticipated 900
NCT03381859 Withdrawn Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4 Phase 4 Interventional HCV treatment expansion occurred in Egypt Actual 0
NCT03386006 Suspended Noom Coach for Bariatric Surgery N/A Interventional COVID-19 Anticipated 50
NCT03386162 Suspended SAFIR PI3K A Phase II Randomized Trial Comparing Alpelisib and Fulvestrant Versus Chemotherapy as Maintenance Therapy in Patients With PIK3CA Mutated Advanced Breast Cancer Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 90
NCT03460548 Terminated REMOGEN® Omega Versus Cationorm® in the Treatment of Patients Suffering From Dry Eye N/A Interventional low recruitment rate Actual 26
NCT02880241 Suspended MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria Phase 2 Interventional Precautionary delay in response to the COVID-19 pandemic. Anticipated 102
NCT03080168 Suspended The "AIM Study": Investigating Whether Actigraphy and Ideation Measures Can Promote Patient Safety Observational Due to Covid-19 Anticipated 175
NCT03225092 Withdrawn Platelet-rich Plasma Injections for Persistent Medial Knee Pain After Total Knee Arthroplasty Early Phase 1 Interventional Unable to recruit enough study participants Actual 0
NCT03287947 Suspended LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal Carcinoma Phase 2 Interventional Low enrollment Actual 5
NCT03325439 Suspended A Study to Test the Pharmacokinetics, Efficacy, and Safety of Brivaracetam in Newborns With Repeated Electroencephalographic Seizures Phase 2/Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 42
NCT03557281 Suspended An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis Phase 2 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 80
NCT03582514 Withdrawn Dose and Volume Escalation of Preoperative Brain Irradiation in GBM Patients -the POBIG Trial - N/A Interventional The participating site went broke and no new participating sites have been found Actual 0
NCT03682848 Suspended Safety and Efficacy of Dolutegravir/Lamivudine (DTG/3TC) in Therapy-naive Human Immunodeficiency Virus-1 (HIV-1) Infected Adolescents Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 30
NCT03709992 Suspended Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms: N/A Interventional Because of COVID-19 Crisis Anticipated 200
NCT03729401 Suspended Personalization of Long-Term Antiplatelet Therapy - RAPID EXTEND Phase 4 Interventional COVID-19 pandemic Anticipated 390
NCT03810118 Suspended Fluid Challenge Infusion and Response N/A Interventional COVID-19 outbreak and elective surgery stopped Anticipated 98
NCT03844282 Suspended Research Evaluating Sports ConcUssion Events - Rapid Assessment of Concussion and Evidence for Return Observational Coronavirus pandemic - University facilities closed Anticipated 120
NCT03900832 Suspended Effects of Heating on Exercise Pressor Reflex in Peripheral Artery Disease: Exercise Ability Early Phase 1 Interventional Temporarily suspended due to Pandemic. Anticipated 32
NCT03903380 Terminated Manual Therapy and Exercise With Mixed Reality With Hololens® Exercise Protocol in Chronic Neck Pain Patiens. N/A Interventional problems recruiting the sample; derived from pandemic situation COVID-19 Actual 14
NCT04021472 Suspended Evaluate Health Coaching Support in Technology-based Interventions for Meeting Health Goals N/A Interventional Trial is suspended due to COVID-19. Anticipated 40
NCT04039191 Suspended SMS Education for Post-operative Pain N/A Interventional COVID 19 Anticipated 250
NCT04059822 Suspended Slow and Deep Breathing to Lower Blood Pressure in Women With Pregnancy-induced Hypertension N/A Interventional Recruitment on hold - COVID-19 Anticipated 67
NCT04123795 Suspended A Study to Evaluate the Efficacy, Safety, and Drug Concentration of Certolizumab Pegol (CZP) in Children and Adolescent Study Participants With Moderate to Severe Chronic Plaque Psoriasis (PSO) Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 150
NCT04167748 Withdrawn Preimplantation Genetic Testing for Aneuploidy (PGT-A) in Women Over 36 Years of Age N/A Interventional Per discretion of principal investigator Actual 0
NCT04167852 Suspended Mindfulness Meditation and Bariatric Surgery N/A Interventional COVID 19 Anticipated 189
NCT04185428 Suspended Investigating Integrative Therapies for Symptom Management in Adults With Acute Myeloid Leukemia N/A Interventional Due to COVID-19 Anticipated 60
NCT04195958 Suspended A Study to Assess the Impact of Omalizumab on Exercise Capacity, Physical Activity, and Sleep Quality in Participants With Moderate to Severe Allergic Asthma Phase 4 Interventional Due to the COVID-19 pandemic, recruitment and screening visits have been suspended until further notice. Anticipated 150
NCT04299282 Suspended CIED Implantation in Low BMI Patients N/A Interventional Postponed due to COVID-19 pandemic Anticipated 20
NCT02658656 Suspended Powered Exoskeletons in Persons With SCI N/A Interventional Administrative hold due to COVID-19 pandemic Anticipated 160
NCT03152084 Terminated The Study Will Evaluate Average 24-hr Sodium Excretion During Dapagliflozin Treatment in Patients With Type 2 Diabetes Mellitus With Preserved or Impaired Renal Function or Non-diabetics With Impaired Renal Function. Phase 4 Interventional Poor recruitment. Actual 25
NCT03229941 Suspended Transfusion Trigger After Operations in High Cardiac Risk Patients N/A Interventional As a consequnce of COVID 19 and after consultation with research oversight, regulatory and monitoring entities enrollment has been placed on a temporary hold. Anticipated 3070
NCT03281044 Terminated Fecal Microbiota Transplantation in Depression Phase 2 Interventional Although not observed in our patients (4 enrolled), SAEs have been reported in other patients receiving the same product. Actual 4
NCT03335059 Terminated Mitomycin C Intravesical Chemotherapy in Conjunction With Synergo® Radiofrequency-Induced Hyperthermia for Treatment of Carcinoma in Situ Non-Muscle Invasive Bladder Cancer Patients Unresponsive to Bacillus Calmette-Guérin, With or Without Papillary Tumors. Phase 3 Interventional poor enrollment Actual 5
NCT03416192 Withdrawn 12 Weeks of Hemodialysis With Medium Cut-Off Filter Compared to Hemodiafiltration With Standard High-flux Filter. N/A Interventional Capacity shortage Actual 0
NCT03600805 Suspended Evaluation of Efficacy and Safety of Sarilumab in Patients With GCA Phase 3 Interventional Suspended (Due to COVID-19) Anticipated 360
NCT03600818 Suspended Evaluation of the Efficacy and Safety of Sarilumab in Patients With Polymyalgia Rheumatica Phase 3 Interventional SUSPENDED (Due to COVID-19) Anticipated 280
NCT03647566 Suspended 18F Sodium Fluoride PET/CT in Acute Aortic Syndrome Observational COVID-19 Pandemic Anticipated 80
NCT03691935 Suspended Erector Spinae Plane Block: For Pain Control in Patients Undergoing Flank Incision Phase 4 Interventional Temporary enrollment restrictions related to global pandemic. Anticipated 40
NCT03737292 Suspended Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy Phase 4 Interventional Temporarily suspended due to Pandemic. Anticipated 40
NCT03766438 Suspended Stories for Change: Digital Storytelling for Diabetes Self-Management Among Hispanic Adults N/A Interventional New recruitment is suspended during COVID-19 pandemic due to institutional guidelines. Anticipated 450
NCT03768986 Suspended A Reinforcement Intervention for Increasing HIV Testing Among At-Risk Women N/A Interventional due to COVID-19 Anticipated 334
NCT03801902 Suspended Accelerated Hypofractionated or Conventionally Fractionated Radiotherapy and Durvalumab in Treating Patients With Stage II-III Non-small Cell Lung Cancer Phase 1 Interventional Scheduled Interim Monitoring Anticipated 24
NCT03872778 Suspended [177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-NeoB Lesion Uptake Phase 1/Phase 2 Interventional Recruitment temporarily paused due to COVID-19 Anticipated 71
NCT03958799 Suspended A Study to Describe the Safety Profile and Compare the Immune Response of 4 Different Formulations of an Investigational Tdap Vaccine When Compared to Licensed Tdap Vaccine in Young Adults in Canada Phase 1 Interventional Suspended (Due to Covid-19) Anticipated 100
NCT03959826 Suspended Promoting Employment in Persons Living With HIV/AIDS N/A Interventional due to COVID-19 Anticipated 144
NCT04064463 Suspended Dual Reinforcement Contingency Management for Alcohol Use Disorders N/A Interventional due to COVID-19 Anticipated 150
NCT04099277 Terminated A Study of LY3435151 in Participants With Solid Tumors Phase 1 Interventional Study terminated due to strategic business decision by Eli Lilly and Company. Actual 2
NCT04129528 Suspended Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Adult Subjects Phase 2 Interventional Study treatment and recruitment has been paused due to COVID-19. Anticipated 102
NCT04142086 Suspended Dose-ranging Study of an Investigational Yellow Fever Candidate Vaccine in Adults Phase 1/Phase 2 Interventional Suspended (Due to Covid-19) Anticipated 572
NCT01072370 Terminated Safety and Effectiveness of Cord Blood Stem Cell Infusion for the Treatment of Cerebral Palsy in Children Phase 1/Phase 2 Interventional Actual 18
NCT02116959 Terminated Alternating Systemic Chemotherapy and Intra-Arterial Melphalan (IAM) Chemotherapy in Children With Intra-Ocular Retinoblastoma Phase 1 Interventional Low accrual Actual 6
NCT00632827 Terminated Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak) Phase 2 Interventional Manufacturing shortage of both Diftitox and Doxil Actual 21
NCT03176537 Withdrawn Periodontal Profile of Hypogonadic Men Phase 4 Interventional No eligible participants for the RCT were found Actual 0
NCT03256617 Terminated The Development of a Cognitive Reassurance Training Program N/A Interventional Recruiting beyond September 10, 2018 would mean that the training occurred more than a year in the past. For this reason, we terminated recruitment. Actual 128
NCT03261661 Suspended Improving Response to Intervention in Students With or at Risk of Reading Disabilities N/A Interventional Schools are currently closed for Covid-19 Anticipated 720
NCT03263429 Suspended Novel PET/CT Imaging Biomarkers of CB-839 in Combination With Panitumumab and Irinotecan in Patients With Metastatic and Refractory RAS Wildtype Colorectal Cancer Phase 1/Phase 2 Interventional Pause for COVID-19 Response Anticipated 40
NCT03661255 Suspended Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska N/A Interventional Enrollment is temporarily paused due to COVID-19 and is expected to resume in the future. IRB approval is not suspended Anticipated 975
NCT03672331 Suspended My Personalized Breast Screening N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 85000
NCT03805659 Suspended HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms N/A Interventional COVID-19 Anticipated 20
NCT03959319 Suspended Comparison of Movement Pattern Training and Manual Therapy for Prearthritic Hip Disorders N/A Interventional This study has been suspended due to the COVID-19 epidemic. The study will resume once the epidemic has ended. Anticipated 40
NCT01164150 Terminated Prospective Randomised Phase II Trial Evaluating Adjuvant Pelvic Radiotherapy Using Either IMRT or 3-Dimensional Planning for Endometrial Cancer. ICORG 09-06 Phase 2 Interventional Actual 92
NCT01949961 Terminated The Norwegian Sonothrombolysis in Acute Stroke Study Part 2 N/A Interventional Lack of funding for researchers Actual 59
NCT04349020 Suspended Patient Reported Outcomes for Acute Asthma Care Treatment Observational COVID-19 Anticipated 77
NCT04349462 Suspended Post Critical Illness Dysphagia in the Intensive Care Unit N/A Interventional Recruitment has been suspended during COVID19 Pandemic Anticipated 300
NCT02559609 Suspended Interventions for Unemployed Hazardous Drinkers N/A Interventional due to COVID-19 Anticipated 280
NCT02726880 Suspended Reducing Internet Gaming N/A Interventional due to COVID-19 Anticipated 40
NCT02777190 Suspended A Comparison of Oral Misoprostol and Vaginal Misoprostol for Cervical Ripening and Induction of Labor Phase 4 Interventional Temporarily suspended due to pandemic Anticipated 110
NCT02814591 Suspended Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy Observational [Patient Registry] Anticipated 245
NCT03473522 Suspended Effects of tDCS Combined With Therapeutic Exercises in Patients With Parkinson's Disease. Phase 2/Phase 3 Interventional We had to suspend our clinical trials due to the pandemic of COVID-19. Anticipated 30
NCT03494114 Suspended Imaging Activated Macrophages in the Lungs Phase 1 Interventional This study has been suspended due to COVID-19 Virus pandemic Anticipated 45
NCT03523156 Suspended Trachoma Elimination Study by Focused Antibiotic (TESFA) Phase 4 Interventional Study is temporarily suspended due to COVID-19 Anticipated 53384
NCT03621657 Terminated The GRAFT Study: Gut RecolonizAtion by Fecal Transplantation Phase 2 Interventional insufficient participant population Actual 1
NCT03826368 Withdrawn Hemp-Derived Botanical Dietary Supplementation During Recovery From Brain Injury Observational Lack of initial funding after approval of study Actual 0
NCT03896295 Suspended An Extension Study of MOM-M281-004 to Evaluate the Safety, Tolerability, and Efficacy of M281 Administered to Patients With Generalized Myasthenia Gravis Phase 2 Interventional This study will undergo a temporarily pause in recruitment (screening and enrollment) due to the COVID-19 pandemic. Anticipated 60
NCT03904017 Suspended The Role of Hyperoxia in Acute Ischemic Stroke N/A Interventional Covid-19 pandemic mandated suspension of research Anticipated 200
NCT04021030 Suspended Building Collaborations to Address Drug Problems in the United States and China N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 20
NCT04119050 Suspended Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia Phase 2/Phase 3 Interventional This study will undergo a temporarily pause in recruitment (screening and enrollment) due to the COVID-19 pandemic. Anticipated 90
NCT04252664 Suspended A Trial of Remdesivir in Adults With Mild and Moderate COVID-19 Phase 3 Interventional The epidemic of COVID-19 has been controlled well at present, no eligible patients can be recruitted. Anticipated 308
NCT04257656 Terminated A Trial of Remdesivir in Adults With Severe COVID-19 Phase 3 Interventional The epidemic of COVID-19 has been controlled well in China, no eligible patients can be enrolled at present. Actual 237
NCT04347343 Suspended Combined NMES and BFR Training After TKA N/A Interventional COVID Restrictions Anticipated 15
NCT02567227 Suspended Cognitive Remediation to Improve Mobility in Sedentary Seniors N/A Interventional The study was suspended on March 13th 2020 due to the COVID-19 pandemic. Anticipated 420
NCT02654925 Suspended Myeloid to Adipocyte Transdifferentiation in Human Cells Observational COVID-19, study will resume when we return to normal operations Anticipated 60
NCT03396978 Suspended The Influence of Gonadal Hormone Suppression on Adipocyte Lineage and the Microbiome N/A Interventional COVID-19; will resume when we return to normal operations Anticipated 20
NCT03475316 Suspended Movement Intervention for Memory Enhancement N/A Interventional The study was suspended on March 13th 2020 due to the COVID-19 pandemic. Anticipated 32
NCT02061774 Terminated Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion Phase 4 Interventional Preliminary analysis showed not clinically significant. Study ended and closed 1/11/2018 Actual 21
NCT03816644 Suspended 5-Cog Battery for Detecting Cognitive Impairment and Dementia N/A Interventional The study has been suspended as of March 13th 2020 due to the COVID-19 pandemic. Anticipated 1200
NCT04311541 Withdrawn A Study of Dexlansoprazole Modified Release (MR) in Gastroesophageal Reflux Disease (GERD) Participants in the Russian Federation Observational Business Decision; No Safety Or Efficacy Concerns Actual 0
NCT01205815 Suspended Storage and Research Use of Human Bio-specimens From Melanoma Patients and Clinical Testing for Assignment of Treatment Observational Pause for COVID 19 Response Anticipated 2500
NCT01872377 Terminated Dose Escalation Study of CyberKnife® SBRT Boost for Patients With Unresectable Locally Advanced Pancreatic Cancer N/A Interventional No longer recruiting patients to this study Actual 7
NCT02471170 Suspended Protocol to Permit the Acquisition of Circulating Tumor Material in Pancreatic Diseases Observational on hold due to COVID-19 Anticipated 100
NCT02634957 Terminated Impact of Duration Of Absolute Voice Rest on Voice Outcome After Phonomicrosurgery N/A Interventional Due to change in available resources Actual 17
NCT02653131 Terminated The Use of DPP-4 Inhibitors in Short Bowel Syndrome Phase 4 Interventional too many side-effects Actual 8
NCT03955783 Suspended Venetoclax and Selinexor in Treating Patients With Relapsed or Refractory High Risk Hematologic Malignancies Phase 1 Interventional Pause for COVID 19 response Anticipated 78
NCT02931448 Withdrawn Occult Carbon Monoxide Poisoning Detection by Pulsated Carboxymetry in an Emergency Department Observational Actual 0
NCT03360357 Withdrawn Laparoscopic Vaginal Cuff Suturing Profienciency for OBGYN Residents N/A Interventional Lack of participants to enroll. Actual 0
NCT03719560 Withdrawn Early Systemic Central Nervous System Prophylaxis in Diffuse Large B-cell Lymphoma Phase 2 Interventional lack of funding Actual 0
NCT04023227 Suspended Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC Phase 4 Interventional Recruitment temporarily paused due to COVID-19 Anticipated 900
NCT02246270 Suspended Recurrent Urinary Tract Infections and Heparin (RUTIH Trial) Phase 1/Phase 2 Interventional Due to COVID-19 Anticipated 30
NCT02256124 Terminated Effect of Lamotrigine on Cognition in NF1 Phase 2/Phase 3 Interventional Due to our experience, the small number of new inclusions, and the uncertainty regarding the COVID-19 outbreak, we have decided to discontinue the study. Actual 41
NCT02524847 Terminated Methoxsalen and Extracorporeal Photopheresis (ECP) for the Treatment of Pediatric Patients With Steroid Refractory Acute Graft Versus Host Disease Phase 3 Interventional Slow enrollment Actual 29
NCT03036566 Suspended Lithium Disilicate (CAD/CAM) Fixed Partial Dentures (FPD) Clinical Study N/A Interventional Interactions are temporarily paused due to COVID-19 and are expected to resume. Actual 30
NCT03036579 Suspended Celtra Duo Computer Assisted Design/Computer Assisted Machining (CAD/CAM) Dental Crown Study N/A Interventional Intervention/interactions are temporarily paused due to COVID-19 and are expected to resume. This is not a suspension of IRB approval Actual 100
NCT03457701 Suspended Anemia Studies in CKD: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat- Iron (ASCEND: Fe) Phase 2 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 12
NCT03705013 Terminated Observational Study of Sub-populations From Cologuard Post-Approval Study (2014-01) Observational Sponsor Decision Actual 51
NCT03716817 Suspended TetricCAD Crown Clinical Study N/A Interventional Interactions are temporarily paused due to COVID-19 and are expected to resume. Actual 50
NCT03745014 Withdrawn Clinical Impact of Fast Phenotypic Antimicrobial Susceptibility Testing on Patients With Gram-Negative Rod Bacteremia N/A Interventional No sites identified with IRB approval Actual 0
NCT04038684 Suspended Healthy Eating, Activity and Reduction of Teen Stress N/A Interventional Recruitment suspended as of March 16, 2020 due to COVID-19 pandemic Anticipated 240
NCT04050683 Suspended Evaluation of Hemodynamic Parameters Following Transjugular Intrahepatic Portosystemic Shunt (TIPS) N/A Interventional Temporarily suspended per institutional directive due to COVID-19. Anticipated 24
NCT04167254 Suspended Sit Down and Play India Phase 1 Interventional Due to country-level restrictions regarding COVID19 Anticipated 100
NCT04341740 Suspended Investigating Marrow Infiltrating Lymphocytes in Renal Cell Carcinoma Early Phase 1 Interventional Due to COVID-19 Anticipated 12
NCT03639090 Suspended Mass Spectrometry in Single Bladder Cancer Cells Observational Due to COVID-19 Anticipated 10
NCT03658395 Suspended Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms N/A Interventional COVID-19 Anticipated 60
NCT03898310 Suspended UTI Prophylaxis With Cranberry Extract After Female Incontinence Surgery N/A Interventional COVID-19 Anticipated 174
NCT01636609 Terminated Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome Phase 1 Interventional In 2013 the FDA put a temporary hold on the trial and the Phase II portion of this study was cancelled. Actual 18
NCT02672475 Suspended Galunisertib and Paclitaxel in Treating Patients With Metastatic Androgen Receptor Negative (AR-) Triple Negative Breast Cancer Phase 1 Interventional Pause for COVID 19 response Anticipated 29
NCT02743793 Terminated A Cohort Study of Operationally Tolerant Allograft Recipients Observational COVID-19 pandemic and potential risks to study participants and study staff. Actual 41
NCT02819440 Suspended PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction Phase 2 Interventional Due to COVID-19 outbreak, study is temporarily suspended. Anticipated 200
NCT02892578 Terminated Systematic Screening With Electrocardiogram for Unknown Atrial Fibrillation in 65 Years Old and Above People in Nursing Home N/A Interventional The Study halted prematurely because the potential for recruitment into the associated center was reached. Actual 287
NCT02945436 Suspended Optimizing HIV Counseling and Testing and Referral Through an Adaptive Drug Use Intervention N/A Interventional halted temporarily due to the novel Coronavirus Actual 258
NCT03135171 Suspended Trastuzumab and Pertuzumab in Combination With Tocilizumab in Subjects With Metastatic HER2 Positive Breast Cancer Resistant to Trastuzumab Phase 1 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval Anticipated 20
NCT03206203 Suspended Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer Phase 2 Interventional Pause for COVID 19 Response Anticipated 185
NCT03267368 Terminated Comprehensive Care Program SBRT N/A Interventional Low enrollment. 1 pt. enrolled & withdrew at 6 wk follow-up. No further enrollment Actual 1
NCT03409419 Suspended PET Imaging of the Immune System Using Analog Probes Observational Covid-19 campus closure Anticipated 10
NCT03488225 Terminated Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia Phase 2 Interventional the study was closed early due to competing trials Actual 4
NCT03562507 Suspended Multi-center Trial of ESK981 in Combination With Nivolumab in Patients With Metastatic Renal Cell Carcinoma Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 47
NCT03585153 Suspended Multicenter Assessment of the Pancreas in Type 1 Diabetes Observational COVID-19 outbreak Anticipated 250
NCT03628144 Withdrawn Immunonutrition to Reduce Toxicities in Non-Small Cell Lung Cancer Phase 2 Interventional Funding unavailable Actual 0
NCT03720574 Suspended Lorcaserin and Behavioral Modification for Overweight and Obesity Management in Chinese Obese Patients Phase 3 Interventional Reassess safety risks and benefits Anticipated 320
NCT03724968 Suspended Nivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II Expression Phase 2 Interventional Pause for COVID 19 Response Anticipated 36
NCT04248205 Suspended Ketamine for Post-operative Analgesia in Hemorrhoidectomy Phase 4 Interventional Due to COVID-19 Anticipated 100
NCT03736356 Suspended Long-term Health Outcomes of AE Casualties Observational [Patient Registry] The study has been paused due to the current COVID-19 pandemic. Actual 119
NCT04248543 Suspended Quantitative MRI for Functional Assessment Following SBRT for Spinal Metastases N/A Interventional COVID-19 Anticipated 20
NCT03758625 Suspended Comparison of Dendritic Cell-Based Therapeutic Vaccine Strategies for HIV Functional Cure Phase 1 Interventional Due to the COVID-19 pandemic, study has been temporarily halted and will resume in the future Anticipated 40
NCT03766009 Suspended Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making N/A Interventional COVID-19 Anticipated 1050
NCT03768531 Withdrawn Safety and Tolerability Study of Nivolumab and Cabiralizumab for Resectable Biliary Tract Cancer Phase 2 Interventional No subjects were enrolled Actual 0
NCT03803566 Suspended Age-independent Decline in Manual Dexterity of Middle-aged and Older Adults N/A Interventional The grant application has not been approved Anticipated 120
NCT03866187 Suspended A Study to Evaluate the Reactogenicity, Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' HBV (Hepatitis B Virus) Viral Vector Vaccines and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection. Phase 1 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing Anticipated 148
NCT03905525 Suspended Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjögren's Syndrome Phase 2 Interventional Coronavirus pandemic Anticipated 260
NCT04345874 Suspended Technical Assistance for Child and Adult Care Food Program in Family Child Care Home N/A Interventional COVID-19 Anticipated 60
NCT03958721 Suspended Capecitabine and Radiotherapy in the Adjuvant Treatment of Resistant Breast Cancer Phase 1 Interventional Pause for COVID 19 response Anticipated 20
NCT03986151 Suspended Anatomical sNuffbox for Coronary anGiography and IntervEntions N/A Interventional Study suspended temporarily due to the SARS-CoV2 pandemic. Anticipated 774
NCT03988634 Suspended Changes in NT-proBNP and Outcomes, Safety, and Tolerability in HFpEF Patients With Acute Decompensated Heart Failure (ADHF) Who Have Been Stabilized During Hospitalization and Initiated In-hospital or Within 30 Days Post-discharge (PARAGLIDE-HF) Phase 3 Interventional COVID-19 Anticipated 800
NCT03992378 Suspended Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis N/A Interventional Due to COVID-19 pandemic Anticipated 34
NCT04006808 Suspended A Study to Test GlaxoSmithKline's (GSK) Candidate Vaccine-GSK1437173A for Prevention of Shingles in Children With Kidney Transplant Phase 2 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing Anticipated 184
NCT04026009 Suspended Study of GlaxoSmithKline's (GSK) Clostridium Difficile Vaccine to Investigate the Safety and Ability to Provoke an Immune Response in the Body When Administered in Healthy Adults Aged 18-45 Years and 50-70 Years Phase 1 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing Anticipated 140
NCT04072406 Suspended A Self-Directed Mindfulness Meditation Intervention in Gynecologic Cancer Patients N/A Interventional Covid-19 Anticipated 80
NCT04126213 Suspended Study of Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline's (GSK)Respiratory Syncytial Virus (RSV)Maternal Unadjuvanted Vaccine in Healthy Pregnant Women (Aged 18 to 40 Years) and Their Infants Phase 2 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 600
NCT04132349 Terminated Ulipristal Acetate in Symptomatic Uterine Fibroid Phase 4 Interventional Ulipristal Acetate was recalled Actual 25
NCT04165304 Terminated Impact on Drinking Behaviour in Sixth-grade Students Through Changing the School Environment N/A Interventional Since schools are closed due to the current corona virus situation, the study cannot be continued. Actual 431
NCT04176939 Suspended A Study to Test GlaxoSmithKline's (GSK) Herpes Zoster (HZ) Subunit Vaccine's Long-term Immune Response in Previously Vaccinated Kidney Transplant Adults and Then to Test if 2 Additional Doses of the Vaccine Are Safe and Able to Generate an Immune Response Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 86
NCT04185415 Suspended A Study to Test the Safety and Tolerability of UCB0107 in Study Participants With Progressive Supranuclear Palsy (PSP) Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 16
NCT04198753 Suspended Skin Characteristics of Parents of Food Allergic Pediatric Patients Observational COVID-19 pandemic Anticipated 160
NCT04205708 Suspended Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma Observational Due to COVID-19 pandemic Anticipated 600
NCT04296344 Suspended Group Acupuncture Therapy With Modified Yoga N/A Interventional COVID-19 Anticipated 150
NCT04301284 Suspended Study of CAD-1883 for Spinocerebellar Ataxia Phase 2 Interventional Suspended due to COVID-19 Anticipated 48
NCT02551484 Terminated Contribution of Near-InfraRed Spectroscopy (NIRS) to the Evaluation of Healing After Amputation of the Leg N/A Interventional The patient population presenting in the department has evolved and no longer allows for the recruitment of the necessary number of patients. Actual 62
NCT02782949 Suspended Curcumin in Preventing Gastric Cancer in Patients With Chronic Atrophic Gastritis or Gastric Intestinal Metaplasia Phase 2 Interventional Participant safety during COVID-19 Anticipated 100
NCT02968810 Suspended Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis Phase 2 Interventional COVID-19 Pandemic Anticipated 80
NCT03206112 Terminated Loss of Depotentiation in Focal Dystonia Early Phase 1 Interventional PI leaving the NIH Actual 6
NCT03538392 Withdrawn Serranator® Alto Post Market Clinical Follow Up (PMCF) Study Observational [Patient Registry] Product not available, study withdrawn Actual 0
NCT03685175 Suspended Effect of Cardiotoxic Anticancer Chemotherapy on the Metabolism of [1-13C]Pyruvate in Cardiac Mitochondria Early Phase 1 Interventional Study temporarily on hold due to COVID19 Anticipated 110
NCT03696433 Suspended Visualizing Vascular Mechanisms of Salt Sensitivity N/A Interventional Due to COVID-19 outbreak, study is temporarily suspended. Anticipated 20
NCT03721835 Terminated Safety Study of Femoral Neck Fracture System N/A Interventional Slow enrollment Actual 15
NCT03536546 Suspended Improving Outcomes for Emergency Department Patients With Alcohol Problems N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 450
NCT03580525 Suspended Nicotine Delivery Rate and Its Abuse Potential: Impact of Menthol Early Phase 1 Interventional Suspended due to Covid-19 Anticipated 70
NCT03798691 Suspended Immunogenicity of Herpes Zoster Subunit Vaccine in Inflammatory Bowel Disease Patients Treated With Vedolizumab Phase 4 Interventional suspended to recruiting due to COVID-19 Anticipated 30
NCT03807063 Suspended Rivogenlecleucel Donor Lymphocyte Immunotherapy in Treating Patients With Recurrent Blood Cancers After Stem Cell Transplant Phase 1 Interventional COVID19 Suspension Anticipated 30
NCT03814798 Withdrawn Study Evaluating IGSC 20% Flexible Dosing in Treatment-Experienced and Treatment-Naive Subjects With Primary Immunodeficiency Phase 3 Interventional Due to the regulatory approval of the product in this indication, a large portion of the study becomes unnecessary. Actual 0
NCT03822663 Suspended The Influence of Caffeine Supplementation on Specific Performance and Training Activities Phase 3 Interventional Pandemic caused by Coronavirus. Anticipated 50
NCT03881241 Terminated Safety Study of Treatment of Leg Fractures Observational Difficulty with enrollment Actual 2
NCT03710824 Suspended Investigating Trends in Quality of Life in Patients With Idiopathic Pulmonary Fibrosis (IPF) Under Treatment With Nintedanib Observational Due to the current COVID-19 pandemic, the enrollment of new patients is temporarily discontinued. Patients who are already enrolled into NIS continue participat Anticipated 120
NCT03968484 Withdrawn Platelet Transfusion in Sepsis Trial N/A Interventional COVID-19 trials gained priority Actual 0
NCT04013971 Suspended Innovative Biofeedback Interface for Enhancing Stroke Gait Rehabilitation N/A Interventional Clinical trial and human subject procedures related to this study are temporarily suspended due to COVID-19 Anticipated 12
NCT04025359 Suspended Effects of Dronabinol in Opioid Maintained Patients Early Phase 1 Interventional Suspended due to Covid-19 Anticipated 20
NCT03772210 Suspended Mechanism and Dosimetry Exploration in TES Magnetic Resonance Current Mapping Methods N/A Interventional Recruiting and interventions suspended due to COVID-19 pandemic Anticipated 80
NCT04070157 Suspended Randomized, Double-Blind, Placebo-Controlled Pilot Study on the Safety and Effectiveness of LUCEMYRA During an Opioid Taper in Treatment of Withdrawal Phase 2 Interventional Enrollment on Hold (COVID-19) Anticipated 60
NCT04081298 Suspended eHealth Diet and Physical Activity Program for the Improvement of Health in Rural Latino Cancer Survivors Phase 2 Interventional COVID19 Suspension Anticipated 40
NCT03842761 Suspended A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 64
NCT04108000 Suspended SPIRIT for Persons With Dementia and Complex Multimorbidity N/A Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 60
NCT03900650 Suspended Men's Sexual Risk Behaviors: Alcohol, Sexual Aggression, and Emotional Factors N/A Interventional COVID-19 pandemic Anticipated 420
NCT04188730 Suspended A Relative Bioavailability Study Comparing Lofexidine Granules for Reconstitution to LUCEMYRA® (Lofexidine) Tablets Phase 1 Interventional Study on Hold Anticipated 16
NCT04198428 Suspended Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0) N/A Interventional Recruitment and enrollment delayed due to covid-19 Anticipated 3600000
NCT04221386 Suspended Melodic Intonation Therapy for Tone Language Speakers N/A Interventional Coronavirus Anticipated 40
NCT04027166 Suspended Cognitive Function and Pain Threshold in People Who Are Methadone Maintained Early Phase 1 Interventional Suspended due to Covid-19 Anticipated 30
NCT04050410 Suspended Autonomic Determinants of POTS - Pilot1 Early Phase 1 Interventional COVID-19 outbreak Anticipated 48
NCT00041288 Terminated Study Of Two Non-Myeloablative Stem Cell Transplant Strategies For Low-Grade Lymphoma And CLL Phase 2 Interventional Poor accrual and difficulty with multicenter logistics Actual 10
NCT01119417 Suspended The Role of Endothelin in the Supine Hypertension of Autonomic Failure Phase 1 Interventional Recruitment is temporarily suspended due to COVID-19 outbreak Anticipated 12
NCT01163786 Terminated A Proposal to Test the Efficacy and Tolerability of Bortezomib in Pulmonary Chronic GVHD Phase 2 Interventional Study was closed due to low accrual before the accrual goal was reached Actual 17
NCT01871766 Suspended Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy Phase 2 Interventional Temporarily closing the study to new enrollments per the statistical design to evaluate intermediate risk patients that have received maintenance therapy. Anticipated 128
NCT02275702 Withdrawn Randomized Study of Preoperative Dexamethasone for Quality of Recovery in VATS Lung Resection Patients Phase 4 Interventional NOL not obtained Actual 0
NCT02417415 Suspended Local Heat Stress in Autonomic Failure Patients With Supine Hypertension N/A Interventional Recruitment is temporarily suspended due to COVID-19 outbreak Anticipated 21
NCT02425566 Suspended Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension Phase 1 Interventional Recruitment is temporarily suspended due to COVID-19 outbreak Anticipated 12
NCT02429557 Suspended Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure Phase 1 Interventional Recruitment is suspended due to COVID-19 outbreak Anticipated 20
NCT02580604 Suspended PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2) Early Phase 1 Interventional COVID-19; Temporary suspension of non-essential human subjects research Anticipated 28
NCT01495819 Suspended Nicotine Reinforcement and Aversion in Young Adult Light Smokers N/A Interventional Suspended due to Covid-19 Anticipated 64
NCT02622386 Suspended The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis Phase 2 Interventional Enrollment and interactions/interventions paused due to COVID-19. Expected to resume in the future. This is not a suspension of IRB approval Anticipated 50
NCT02670525 Suspended Matched Targeted Therapy For High-Risk Leukemias and MDS N/A Interventional Temporarily closed for interim data analysis. Anticipated 200
NCT02725060 Suspended Autoimmune Basis for Postural Tachycardia Syndrome N/A Interventional Recruitment is temporarily suspended due to COVID-19 outbreak Actual 58
NCT02211274 Withdrawn VA Community Living Centers to Home N/A Interventional Due to issues with the study, we did not proceed with enrolling participants in the trial. Actual 0
NCT02889159 Suspended Immunologic Profile of Chronically Photodamaged Skin N/A Interventional Enrollment and interactions/interventions paused due to COVID-19. Expected to resume in the future. This is not a suspension of IRB approval Anticipated 40
NCT02897063 Suspended Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure Phase 1 Interventional Recruitment is temporarily suspended due to COVID-19 outbreak Anticipated 34
NCT02945423 Withdrawn Improving the Understanding of Catatonia in Autism Observational funding issues Actual 0
NCT03030131 Terminated Immune Neoadjuvant Therapy Study of Durvalumab in Early Stage Non-small Cell Lung Cancer Phase 2 Interventional Definitive discontinuation according to safety monitoring of death from the 46th patient onwards. Anticipated 81
NCT03042988 Suspended Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension N/A Interventional Recruitment is temporarily suspended due to COVID-19 outbreak Anticipated 20
NCT02503501 Terminated Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease Phase 2 Interventional Study will not have power to show a difference between groups. Actual 49
NCT03057002 Suspended UTSW HP [13-C] Pyruvate Injection in HCM Observational Study temporarily on hold due to COVID19 Anticipated 10
NCT03084146 Suspended The Role of Food Sensitivity in Psoriasis N/A Interventional Enrollment and interactions/interventions paused due to COVID-19. Expected to resume in the future. This is not a suspension of IRB approval Anticipated 70
NCT03093155 Suspended Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab Phase 2 Interventional Temporary pause on enrollment due to COVID-19 Anticipated 88
NCT03159429 Terminated Nasal Ventilation Versus Voluntary Hypoventilation in the Rehabilitation of Hyperventilation Syndrome N/A Interventional Staff no longer available. Actual 19
NCT03292432 Suspended Triggered Escalating Real-time Adherence (TERA) Intervention N/A Interventional Participant study visits are temporarily suspended due to COVID-19. Actual 88
NCT03312556 Suspended Treatment of Supine Hypertension in Autonomic Failure (CPAP) N/A Interventional Recruitment is temporarily suspended due to COVID-19 outbreak Anticipated 12
NCT03318094 Suspended Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity Phase 1 Interventional COVID 19 outbreak Anticipated 36
NCT03127254 Withdrawn Can Making Video Narratives Benefit Adolescents With Cancer N/A Interventional Research cancelled Actual 0
NCT03361137 Terminated Study of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures Phase 4 Interventional The Sponsor decided to terminate the study early for several reasons (low enrollment, limited variety of surgery types, and available scientific data). Actual 14
NCT03487484 Terminated Quality of Life in Patients With Rectal Cancer Receiving Total Mesorectal Excision With or Without Stoma Observational insufficient recruitment Actual 5
NCT02906696 Terminated Bosutinib in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase After Frontline TKI Failure Phase 2 Interventional Terminated per PI's request due to competing priorities. Actual 8
NCT03327649 Suspended Neuromodulation to Treat Patients With Heart Failure With Preserved Ejection Fraction N/A Interventional Due to COVID-19 Anticipated 72
NCT03337256 Suspended Direct Discharge of Patients With Upper Gastrointestinal Bleeding From the Emergency Department After Endoscopy N/A Interventional Anticipated 762
NCT03400852 Terminated A Study to Assess the Efficacy and Safety of MNK-1411 in Duchenne Muscular Dystrophy Phase 2 Interventional Slow enrollment Actual 44
NCT03440944 Suspended Superior Venous Access, Midline vs Ultrasound IVs N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 30
NCT03490968 Suspended The Impact of Branched-Chain Amino Acid Metabolism on Limb Dysfunction in PAD N/A Interventional Due to COVID-19 outbreak, study is temporarily suspended. Anticipated 100
NCT03284099 Terminated Bedtime ACEIs/ARBs Versus Morning ACEIs/ARBs for Reverting Non-dipping Hypertension Phase 4 Interventional No funding obtained. The ABPM machines are being used for another project Actual 4
NCT03549468 Suspended The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy N/A Interventional Due to COVID-19 Anticipated 60
NCT03585010 Suspended Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders N/A Interventional Study is temporarily paused because of COVID-19 Anticipated 226
NCT03427021 Terminated A Randomized Study to Establish the Efficacy of Oral Ice Exposure During Oxaliplatin Infusion in Preventing Oral Cold Sensitivity Early Phase 1 Interventional final study report has been completed and submitted Actual 65
NCT03623386 Suspended Effect of Mental Imagery Training on Brain Plasticity and Motor Function in Individuals With Parkinson's Disease N/A Interventional due to COVID-19 outbreak Anticipated 50
NCT03659136 Suspended The XENERA™ 1 Study Tests Xentuzumab in Combination With Everolimus and Exemestane in Women With Hormone Receptor Positive and HER2-negative Breast Cancer That Has Spread Phase 2 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 80
NCT03709771 Suspended Novel Mechanisms and Predictors of VEGF Receptor Inhibitor- or Immune Checkpoint Inhibitor-Associated Hypertension and Cardiovascular Disease Observational Due to COVID-19 outbreak, study is temporarily suspended. Anticipated 80
NCT03582800 Suspended Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study Phase 2 Interventional Covid-19 pandémie Anticipated 40
NCT03718104 Suspended MOM NEST Study: Maternal Opioid Medication: Naltrexone Efficacy Study Observational Currently suspended due to COVID-19 policies. Anticipated 100
NCT03727009 Terminated Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Hematologic Malignancies Observational COVID-19 Actual 409
NCT03727087 Terminated Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Melanoma Observational COVID-19 Actual 330
NCT03740477 Suspended Screening for Atrial Fibrillation in Native AmeRicans Using iPhone ECG N/A Interventional Due to COVID-19 Anticipated 1500
NCT03765398 Suspended VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment N/A Interventional COVID-19 outbreak and stay-at-home executive orders to promote social distancing Anticipated 50
NCT03856255 Suspended Polyp Measurement Device N/A Interventional Covid-19 Anticipated 150
NCT03869138 Suspended Alternative Therapies for Improving Physical Function in Individuals With Stroke N/A Interventional Suspended [COVID-19 outbreak and to promote social distancing] Actual 20
NCT03742167 Suspended Simulation RCT of Telemedical Support for Paramedics N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 108
NCT03904615 Suspended Geriatric Recovery Using Inpatient and Post-hospitalization Supplementation Phase 1 Interventional recruitment temporarily suspended due to COVID-19 Anticipated 210
NCT03935126 Suspended Global Atrophie Biomarker Evaluation Study (GABiE) N/A Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 50
NCT03953508 Suspended Perceptions of Cigarette Smoking in Young Adults N/A Interventional Study is paused due to COVID-19 Anticipated 300
NCT03846596 Terminated Flow Cytometry Analysis of the Reactive Oxygen Species in Immature Granulocytes in Septic Patient Observational Not enough patient Actual 34
NCT03964207 Suspended A Study on Whether Patients Prefer the Spiriva® Respimat® or the Spiriva® Handihaler® for Treating Their Chronic Obstructive Pulmonary Disease (COPD) Phase 4 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 71
NCT03971539 Suspended Evaluation of Safety and Tolerability of BI 894416 in Patients With Mild Asthma Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 80
NCT04057742 Suspended AlloSure for the Monitoring of Antibody Mediated Processes After Kidney Transplantation Observational due to COVID-19 Anticipated 100
NCT03914612 Suspended Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer Phase 3 Interventional Other - COVID-19 Anticipated 810
NCT04063124 Suspended Senolytic Therapy to Modulate Progression of Alzheimer's Disease Phase 1/Phase 2 Interventional Enrollment suspended due to pandemic Anticipated 5
NCT04068493 Suspended A Dissonance-Based Obesity Intervention N/A Interventional Recruitment has been temporarily closed due to COVID-19 Anticipated 32
NCT03956589 Terminated Functional Respiratory Imaging and Orkambi in CF Phase 4 Interventional Patient inclusion has stopped after interim analysis. Actual 12
NCT04085796 Suspended ICCI for Older Patients in A&E Observational Covid19 emergency Anticipated 15
NCT04123067 Suspended Pioglitazone Treatment for Hyperglycemic Acute Ischemic Stroke Phase 1/Phase 2 Interventional Temporarily suspended due to Pandemic. Anticipated 50
NCT04078126 Suspended Study Comparing Dual Combination of Product (Budesonide and Formoterol) Given Via Two Different Inhalers. To See Which One Results in the Best Effect on Breathing. Phase 3 Interventional Study put on hold by sponsor due to COVID-19 pandemic Anticipated 30
NCT04160299 Suspended Effectiveness of Alternative Therapy for Improving Cognition, Balance, and Physical Activity N/A Interventional Temporarily suspended due to the COVID-19 pandemic Anticipated 20
NCT04089202 Suspended Diabetes eConsult Non-Inferiority Study N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 152
NCT04166630 Suspended Diagnosing Intensive Care Unit (ICU) Acquired Weakness N/A Interventional Enrollment suspended due to COVID-19 Anticipated 150
NCT04205279 Suspended Reactive Balance Training for Fall Prevention N/A Interventional COVID-19 outbreak and stay at home executive order to promote social distancing Anticipated 90
NCT04101071 Suspended Alternative Substrates in the Critically Ill Subject N/A Interventional Due to COVID-19 pandemic Anticipated 37
NCT04239872 Suspended Fluoride Retention in the Mouth of Older Adults Phase 1 Interventional Enrollment is temporarily paused due to COVID-19 and is expected to reopen in the future. This is not a suspension of IRB approval. Anticipated 20
NCT04243616 Suspended Study of PD-1 Inhibition With Cemiplimab in Locally Advanced Hormone Receptor (HR) Positive HER2 Negative or Triple-Negative Breast Cancer Patients Undergoing Standard Neoadjuvant Chemotherapy Phase 2 Interventional Accrual is suspended due to COVID-19. Anticipated 36
NCT04249557 Suspended Exercise is Medicine: a Cohort Study N/A Interventional Due to the COVID-19, all sport centers were closed Anticipated 6000
NCT04280549 Suspended Platelet PAR-1 Activation in Health and Diabetes Observational Due to COVID-19 outbreak, study is temporarily suspended. Anticipated 50
NCT04293874 Suspended Adaptive Symptom Care Using Fish-Based Nutritional Directives Post Breast Cancer N/A Interventional Related to COVID-19, we are continuing data analysis at this time Anticipated 150
NCT04314206 Suspended VNRX-5024 Safety and PK in Healthy Adult Volunteers Phase 1 Interventional Infectious Disease Outbreak: COVID-19 Anticipated 36
NCT04234334 Suspended Benefits of Eggs in Combination With a Plant-based Diet N/A Interventional Due to COVID-19 pandemic. Expected to resume at later date. Anticipated 30
NCT02133248 Suspended Identification of Donor Specific B Cells and Antibody Mediated Rejection Observational due to COVID-19 Anticipated 50
NCT02484287 Suspended Quality Control: A Prospective Analysis of EVD Effectiveness N/A Interventional Due to COVID-19 Anticipated 252
NCT02534168 Suspended Post-surgical Pain Assessment in Children: Roles of Skin Conductance and Genomics N/A Interventional Temporarily suspended due to Pandemic Anticipated 160
NCT02562625 Terminated Trial of Pembrolizumab and Radiotherapy in Melanoma Phase 2 Interventional Slow Recruitment Anticipated 234
NCT02710669 Suspended New Formulations of Propafenone to Treat Atrial Fibrillation Phase 1/Phase 2 Interventional Anticipated 243
NCT02730780 Suspended The Natriuretic Peptide System in African-Americans. N/A Interventional Due to COVID-19 outbreak, study is temporarily suspended. Anticipated 80
NCT02825719 Terminated Ulipristal Use in Chinese Population Phase 4 Interventional Ulipristal was withdrawal from the market Actual 31
NCT02904434 Withdrawn Gastrointestinal Implications of Voriconazole Exposure Observational IRB terminated the study Actual 0
NCT02990520 Suspended Prevalence of Malnutrition and/or Sarcopenia at Hospital Admission Observational recruitment temporarily suspended due to COVID-19 Anticipated 100
NCT02990533 Suspended Muscle Anabolic Interventions to Accelerate Recovery From Hospitalization in Geriatric Patients Phase 1 Interventional recruitment temporarily suspended due to COVID-19 Anticipated 80
NCT03118050 Suspended Identifying Therapeutic Targets of Accelerated Sarcopenia N/A Interventional recruitment temporarily suspended due to COVID-19 Anticipated 102
NCT03164551 Terminated TICON-Day 3, Time Lapse Versus Conventional Method in Day 3 Embryo Culture and Assessment Phase 4 Interventional Subject enrollment has remained significantly behind plan despite increased site enrollment activity. Actual 435
NCT03181542 Suspended Infra Red Vein Visualization: Efficacy vs. Standard Technique N/A Interventional Temporarily suspended due to Pandemic Anticipated 139
NCT03199729 Suspended Aging and Mixed Perturbation Training to Reduce Falls in Locomotion N/A Interventional COVID-19 outbreak and stay-at-home executive orders to promote social distancing Anticipated 600
NCT03205527 Suspended Perturbation Training for Fall-risk Reduction Among Stroke Survivors N/A Interventional COVID-19 outbreak and stay at home executive order to promote social distancing Anticipated 181
NCT03238196 Suspended Fulvestrant, Palbociclib and Erdafitinib in ER+/HER2-/FGFR-amplified Metastatic Breast Cancer Phase 1 Interventional Pause for COVID 19 Response Anticipated 32
NCT03259893 Suspended Secondary Prevention of Atrial Fibrilation N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 50
NCT03166631 Suspended A Trial to Find the Safe Dose for BI 891065 Alone and in Combination With BI 754091 in Patients With Incurable Tumours or Tumours That Have Spread Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 104
NCT03230097 Suspended This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 Year Phase 2 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 300
NCT03313947 Withdrawn Airway Ultrasound Prediction and Correlation N/A Interventional PI was unable to perform ultrasound of airway. Actual 0
NCT03219359 Suspended Autologous Stem Cell Transplant for Crohn's Disease Phase 2 Interventional Temporary suspension of enrollment due to COVID-19 situation Anticipated 50
NCT03433898 Suspended This Study Aims to Find a Safe and Effective Dose of BI 754091. The Study Also Aims to Find Safe and Effective Doses of BI 754091 and BI 754111 in Combination. This Study is Done in Asian Patients With Different Types of Cancer Early Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 156
NCT03227458 Suspended DHEA Augmentation of Musculoskeletal Adaptations to Exercise in Older Women N/A Interventional COVID19 Anticipated 225
NCT03449381 Suspended This Study Aims to Find the Best Dose of BI 907828 in Patients With Different Types of Advanced Cancer (Solid Tumors) Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 102
NCT03244033 Suspended Integrating Contextual Factors Into Clinical Decision Support N/A Interventional Reduce COVID-19 risk to research personnel until safe to resume. Anticipated 500
NCT03255473 Suspended High Dose Oral Steroids in Sudden Sensorineural Hearing Loss Phase 2 Interventional On hold due to COVID-19 outbreak Anticipated 208
NCT03574220 Withdrawn Pembrolizumab After Lung SBRT for Medically Inoperable Early Stage Non-small Cell Lung Cancer Early Phase 1 Interventional No accrual - closed by PRMC Actual 0
NCT03598842 Suspended Tuberculosis - Learning the Impact of Nutrition N/A Interventional Enrollment suspended due to covid-19 policies. Anticipated 120
NCT03344159 Suspended Spironolactone Therapy in Chronic Stable Right HF Trial Phase 4 Interventional Covid 19 pandemic Anticipated 30
NCT03396653 Suspended Peer Support for Weight Loss Maintenance N/A Interventional Due to COVID-19 Anticipated 498
NCT03695393 Suspended Stigma, Risk Behaviors and Health Care Among HIV-infected Russian People Who Inject Drugs N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 100
NCT03480373 Suspended Electronic Cigarette Use During Pregnancy Observational Covid-19 pandemic Anticipated 375
NCT03519880 Suspended A Pilot Study of the Utility of 3D Printed Masks for ALS Subjects N/A Interventional COVID-19 research restrictions Anticipated 40
NCT03780725 Suspended This Study Tests How BI 754111 is Distributed in Patients With Advanced Non-small Cell Lung Cancer or Patients With Head and Neck Cancer Who Are Treated With BI 754091 Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 40
NCT03572257 Withdrawn Quetiapine Treatment for Pediatric Delirium Phase 2/Phase 3 Interventional Closed due to inability to enroll Actual 0
NCT03572634 Terminated Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL Phase 1/Phase 2 Interventional Given the extensive time projected to conclude the study hypothesis, it is no longer feasible to include this study of TP-0903. Actual 3
NCT03861234 Suspended A Study to Test Different Doses of BI 836880 in Patients With an Eye Disease Called Wet Age-related Macular Degeneration (wAMD) Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 42
NCT03598894 Suspended Hypertension Chronobiome Observational COVID-19 Anticipated 150
NCT03628638 Suspended Blood Sample Collection in Subjects Participating in a Lung Cancer Screening Program Observational COVID-19 Actual 1718
NCT03633006 Suspended Blood Sample Collection in Subjects With Pulmonary Nodules or CT Suspicion of Lung Cancer or Pathologically Diagnosed Lung Cancer Observational COVID-19 Actual 3298
NCT03716349 Suspended Esthetics of Dental Composite and Adhesive System N/A Interventional paused temporarily due to covid-19 Anticipated 80
NCT03972150 Suspended A Study to Find the Best Dose of BI 836880 Alone and in Combination With BI 754091 in Japanese Patients With Different Types of Advanced Cancer Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 21
NCT03979820 Suspended A Study in Healthy People to Test How Combining BI 1467335 and Tyramine Affects Blood Pressure Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 62
NCT03993119 Suspended This Study Observes the Usage of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) in Elderly Patients With a Heart Rhythm Disorder in Spain Observational Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 500
NCT04002310 Suspended A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic Atrophy Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 18
NCT03749499 Suspended Targeting of UnControlled Hypertension in Emergency Department N/A Interventional The Emergency Department has temporarily suspended research activities due to COVID19. Actual 107
NCT03795233 Suspended Fecal Microbiota Transplant for Primary CDI Phase 1/Phase 2 Interventional Currently suspended due to covid-19 policies. Anticipated 15
NCT04093024 Suspended A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD). Phase 3 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 30
NCT04102462 Suspended A Study to Test How Well Healthy Men Tolerate Different Doses of BI 764198 Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 52
NCT03867396 Suspended Evaluation of Speech-in-noise Performance in Cochlear Implant Recipients With a CROS Device on the Contralateral Ear N/A Interventional On hold due to COVID-19 outbreak Anticipated 50
NCT04111458 Suspended A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation) Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 140
NCT04137289 Suspended A First-in-human Phase Ia/b, Open Label, Multicentre, Dose Escalation Study of BI 905711 in Patients With Advanced Gastrointestinal Cancers Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 140
NCT04138823 Suspended A Study to Test Different Doses of BI 891065 Alone and in Combination With BI 754091 in Asian Patients With Different Types of Advanced Cancer (Solid Tumours) Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 24
NCT04147247 Suspended A Trial to Find the Safe Dose for BI 905681 in Patients With Incurable Tumours or Tumours That Have Spread Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 60
NCT04176536 Suspended A Study in People With Normal Kidney Function and People With Reduced Kidney Function to Test How BI 764198 is Processed in the Body Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 32
NCT04194645 Suspended A Study in Healthy Men to Test How the Body Takes up and Tolerates Different Doses of BI 474121, and Whether it Makes a Difference if BI 474121 is Taken as a Tablet or a Drink. Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 68
NCT04223843 Suspended A Study to Test the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler in People With Chronic Obstructive Pulmonary Disease (COPD) Who Have Different Abilities to Inhale Phase 4 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 200
NCT04232839 Suspended A Study in Healthy Men to Find the Best Formulation of BI 894416 and to Test How This is Taken up in the Body Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 42
NCT04241458 Suspended A Study to Test How Well Healthy Men and Women Tolerate Different Doses of BI 706321 Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 60
NCT03986398 Terminated Nosocomial Infections During Total Prostatic Cystectomies (TPC) With Replacement Enterocystoplasty: Prophylactic Role of Urell®, Cranberry Fruit Juice Extract (Vaccicium Macrocarpon) N/A Interventional In the perioperative setting of radical cystectomy-bladder replacement no improvement of UTI was noticed in 10 patients who took Urell following the protocol Actual 10
NCT04267276 Suspended A Study in Healthy Men to Test How BI 1265162 is Taken up and Processed by the Body Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 16
NCT04069234 Withdrawn Study in Diabetes Mellitus Patients Without Prior Myocardial Infarction or Stroke Undergoing Elective Percutaneous Coronary Intervention. Phase 3 Interventional Sponsor decided to stop the study due to commercial reasons. Actual 0
NCT04086589 Suspended Restoring Molecular Circadian Rhythm Observational COVID-19 Anticipated 40
NCT04093232 Suspended Synovial Fluid Biomarkers Pre and Post Hymovis Knee Injection Observational COVID-19 Institutional policy recruitment temporarily halted through April 2020 Anticipated 50
NCT04095533 Terminated ICU Associated Weakness and Bedside Ultrasound Assessment Observational Coronavirus pandemic halted in-unit enrolment and participation Actual 11
NCT04105543 Suspended CLR 131 Combined With Radiation for Head and Neck Cancer Phase 1 Interventional due to COVID-19 Anticipated 24
NCT04133909 Suspended Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE) Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 800
NCT02881047 Terminated Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures N/A Interventional Actual 8
NCT04151160 Suspended Point of Care Ultrasound Measurements of Perioperative Edema in Infants With Congenital Heart Disease Observational On hold due to COVID-19 outbreak Anticipated 200
NCT04200937 Withdrawn Malleable Treatment - the Tactra Erectile Restoration Study Observational This study has been withdrawn due to COVID-19. Actual 0
NCT04225442 Suspended The Physiological Chronobiome Modified by Age, Sex and Under Evoked Conditions N/A Interventional COVID-19 Anticipated 48
NCT04236583 Suspended Improving the Hospital-to-Home Transition Through Post-Discharge Virtual Visits in Primary Care N/A Interventional Per IRB COVID-19 guidance on conducting human subjects research Anticipated 25
NCT04300855 Suspended Clinical Trial of Green Tea Catechins in Men on Active Surveillance Phase 2 Interventional Safety concerns related to COVID-19 Anticipated 135
NCT04325672 Withdrawn Convalescent Plasma to Limit Coronavirus Associated Complications Phase 2 Interventional Study stopped due to opening Expanded Access Protocol. Actual 0
NCT00667953 Terminated Study of Temzolomide and Gleevec in Advanced Melanoma Phase 1/Phase 2 Interventional Difficulty enrolling subjects Actual 32
NCT01113502 Terminated Eltrombopag in Elderly Acute Myelogenous Leukemia (AML) Phase 1/Phase 2 Interventional Actual 44
NCT01486784 Terminated A Phase I-II Open Label Non-Randomized Study Using TL32711 for Patients With Acute Myelogenous Leukemia, Myelodysplastic Syndrome and Acute Lymphoblastic Leukemia Phase 1/Phase 2 Interventional Actual 27
NCT02048852 Suspended Manipulating Tobacco Constituents in Female Menthol Smokers N/A Interventional COVID-19 pandemic Anticipated 320
NCT02417974 Suspended Prevention of Recurrence of Crohn's Disease by Fecal Microbiota Therapy (FMT) Phase 2 Interventional Currently suspended due to COVID-19 policies. Anticipated 44
NCT02323100 Suspended Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis) Phase 1/Phase 2 Interventional On Hold due to COVID-19 outbreak Anticipated 36
NCT02520011 Terminated Alvocidib Biomarker-driven Phase 2 AML Study Phase 2 Interventional Due to slow enrollment, the extensive time projected to conclude the study hypothesis rendered the study no longer reasonably feasible to complete. Actual 104
NCT02952248 Suspended A Trial to Find and Investigate a Safe Dose of a New Substance (BI 754091) for Patients With Solid Tumours Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 145
NCT02265510 Terminated An Open-Label Study of a Novel JAK-inhibitor, INCB052793, Given to Patients With Advanced Malignancies Phase 1/Phase 2 Interventional Actual 83
NCT03017885 Suspended Post Marketing Surveillance of Nintedanib in Indian Patients With Non-small Cell Lung Cancer (NSCLC) After First-line Therapy Observational Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 100
NCT03047031 Suspended Post Marketing Surveillance of Nintedanib in Indian Patients With Idiopathic Pulmonary Fibrosis Observational Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 400
NCT03156114 Suspended This Study Tests the New Medicine BI 754111 Alone or in Combination With Another New Substance BI 754091 in Patients With Advanced Cancer. The Study Tests Different Doses to Find the Best Dose for Continuous Treatment. Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 215
NCT03165240 Suspended This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 84
NCT03645408 Suspended The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers Phase 1 Interventional Due to COVID-19 policies. Anticipated 36
NCT03334812 Terminated Study on Safety, Tolerability and Prelimenary Efficacy of LNA043 in Patients Undergoing Autologous Chondrocyte Implantation Phase 2 Interventional This study was terminated early based on an interim analysis of 14 subjects, which demonstrated a favorable safety and tolerability profile. Actual 14
NCT03824769 Suspended Physical Activity Choices Everyday N/A Interventional COVID-19 Anticipated 130
NCT04066829 Suspended Default Dosing Settings for Opioid Prescriptions to Adolescents and Young Adults After Tonsillectomy N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval Anticipated 450
NCT02845453 Suspended Treatment With Quetiapine for Youth With Substance Use Disorders and Severe Mood Dysregulation Phase 4 Interventional Currently suspended due to COVID-19 policies. Anticipated 56
NCT03601728 Suspended A Personalized Prehabilitation Intervention In Elective Joint Replacement Surgery N/A Interventional Covid-19 Crisis Anticipated 28
NCT03917823 Terminated Intercostal Cryoneurolysis Following Traumatic Rib Fractures N/A Interventional Revised protocol to such a significant degree that we simply closed this study and started a new study. Actual 4
NCT04098302 Suspended Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy Phase 2/Phase 3 Interventional COVID-19 pandemic Anticipated 190
NCT04208815 Suspended Evaluation of Dietary Milk Polar Lipids on Serum Cholesterol and Gut Microbiota in Healthy Adults N/A Interventional COVID-19 Anticipated 25
NCT02502435 Suspended Human Plasma Fatty Acid Oscillations Observational COVID-19 Anticipated 12
NCT02945085 Suspended 3D Team Care for Cognitively Vulnerable Older Adults N/A Interventional Due to COVID-19, in-person consent and screening procedures could not be continued. Anticipated 956
NCT03133559 Suspended Mapping the Human HIV Chronobiome Observational Protocol Modification is pending Actual 80
NCT03181256 Suspended Early Detection of Lung Cancer Observational Pause for COVID-19 Response Anticipated 154
NCT03271528 Suspended Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers Phase 1 Interventional Due to COVID-19 policies. Anticipated 28
NCT03286062 Terminated VM110 in Detection of Microscopic Tumors: A Phase I Study Phase 1 Interventional Slow accrual Actual 1
NCT03099174 Suspended This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer. Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 148
NCT03374319 Suspended Somatotopic Configuration of Distal Residual Limb Tissues in Lower Extremity Amputations N/A Interventional temporary suspension due to COVID-19 Anticipated 20
NCT03458104 Withdrawn Modeling the Effects of Vocal Cord Atrophy on Airflow and Voice Quality in Elderly Individuals N/A Interventional Recruitment logistics Actual 0
NCT03343704 Suspended This Study Looks at the Effects of Idarucizumab in Patients Who Take Dabigatran and Need Emergency Surgery or Are Bleeding Phase 3 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 20
NCT03534687 Suspended Exercise and the Receptor for Advanced Glycation End Products (RAGE) N/A Interventional Enrollment is temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 60
NCT03351244 Suspended This Study Tests Whether BI 409306 Prevents Patients With Schizophrenia From Becoming Worse. This Study Looks at How Well Patients Tolerate BI 409306 and How Effective it is Over 6 Months Phase 2 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 387
NCT03429543 Suspended Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM Phase 3 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 186
NCT03607682 Suspended Tumor-Treating Fields Therapy in Preventing Brain Tumors in Participants With Extensive-Stage Small Cell Lung Cancer N/A Interventional Paused for COVID-19 response Anticipated 25
NCT03468426 Suspended A Study to Test Different Doses of BI 836880 Combined With BI 754091 in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 245
NCT03662204 Suspended Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid Tumors Observational COVID-19 Anticipated 7500
NCT03717012 Suspended Study of Pulmonary Rehabilitation in Patients With Idiopathic Pulmonary Fibrosis (IPF) Phase 4 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 290
NCT03604445 Suspended This Study Aims to Find and Test a Safe Dose of BI 905677 in Patients With Different Types of Cancer (Solid Tumours) Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 60
NCT03818737 Suspended Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES) Phase 3 Interventional Enrollment suspended due to COVID-19, pre-screening continues for future enrollment Anticipated 480
NCT03826030 Suspended Transcranial Direct Current Stimulation for Post-stroke Motor Recovery Phase 2 Interventional Stopped until further notice due to COVID-19 restrictions Anticipated 129
NCT03697304 Suspended Platform Trial Evaluating Safety and Efficacy of BI 754091 Anti- PD-1 Based Combination Therapies in PD-(L)1 naïve and PD- (L)1 Pretreated Patient Populations With Advanced/Metastatic Solid Tumours. Phase 2 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 260
NCT03752970 Suspended A Study Testing How BI 655130 Works in Patients With Fistulizing Crohn's Disease Phase 2 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 28
NCT03882073 Suspended A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception N/A Interventional temporary suspension due to COVID-19 Anticipated 20
NCT03898375 Terminated The Effect of Optic Flow During Treadmill Walking on the Gait Pattern in People Post-stroke N/A Interventional Technical problems Actual 2
NCT03854474 Suspended Tazemetostat and Pembrolizumab in Treating Patients With Locally Advanced or Metastatic Urothelial Carcinoma Phase 1/Phase 2 Interventional Scheduled Interim Monitoring Anticipated 30
NCT03859973 Suspended This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia Phase 2 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 200
NCT03957577 Suspended Etiology of Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in Japan Observational Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 110
NCT04063592 Suspended AMI Construction in Lower Extremity Residual Limbs N/A Interventional temporary suspension due to COVID-19 Anticipated 20
NCT04066816 Suspended Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption N/A Interventional Due to COVID-19 recruitment has been stopper until further notice. Anticipated 50
NCT03964233 Suspended A Study in Patients With Different Types of Advanced Cancer (Solid Tumors) to Test Different Doses of BI 907828 in Combination With BI 754091 and 754111 Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 170
NCT03971695 Suspended A Study to Test How Well Healthy Men Tolerate Different Doses of BI 706321 Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 80
NCT04059094 Suspended A 4-week Study to Test Different Doses of BI 1265162 in Adolescents and Adults With Cystic Fibrosis Using the Respimat® Inhaler - BALANCE - CF™1 Phase 2 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 98
NCT04131517 Suspended A Study to Test the Interaction of Padsevonil With Oral Contraceptives in Healthy Female Participants Phase 1 Interventional Due to incidence of AEs, recruitment was halted for protocol amendment to alter IMP dosing posology Anticipated 40
NCT04107805 Suspended A Study in Healthy Men and Women to Test How Well Different Doses of BI 1323495 Are Tolerated Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 60
NCT04144738 Suspended Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C" Observational COVID-19 Anticipated 12500
NCT04144751 Suspended Blood Collection Sub-Study of Exact Sciences Protocol 2019-01: "Clinical Validation of an Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, For Colorectal Cancer Screening BLUE-C" Observational COVID-19 Anticipated 12500
NCT04147234 Suspended A Study to Find the Best Dose of BI 1387446 Alone or in Combination With BI 754091 in Patients With Different Types of Advanced or Metastatic Cancer (Solid Tumors) Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 266
NCT04147260 Suspended Evaluation of Photosafety of BI 730357 Compared to Placebo and the Known Photosensitizing Agent Ciprofloxacin Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Actual 48
NCT04257032 Suspended A Study in Healthy Men to Test the Influence of BI 1323495 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood Phase 1 Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Actual 14
NCT00897117 Suspended Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer Observational Pause for COVID-19 Response Anticipated 4000
NCT00898313 Suspended Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer Observational Pause for COVID-19 Response Anticipated 3000
NCT01475500 Suspended Nashville Early Diagnosis Lung Cancer Project Observational Pause for COVID-19 Response Anticipated 410
NCT01809756 Terminated The Effect of Caphosol® on the Development of Esophagitis in (N)SCLC Patients Treated With Concurrent Chemo/Radiotherapy N/A Interventional bad taste of Caphosol - early stop of intake by patients Actual 55
NCT02448225 Suspended 18F-FSPG PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules Phase 2 Interventional Pause for COVID-19 Response Anticipated 60
NCT01312376 Terminated Autologous T-Cells Combined With Autologous OC-DC Vaccine in Ovarian Cancer Phase 1 Interventional Anticipated 12
NCT02552225 Suspended Treatment of Chronic Laryngitis With Amitriptyline Phase 2/Phase 3 Interventional Currently suspended due to covid-19 policies. Anticipated 138
NCT02750865 Suspended Conversational Agents to Improve Quality of Life in Palliative Care N/A Interventional Currently suspended due to COVID-19 policies Anticipated 823
NCT02981082 Terminated Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension Phase 1 Interventional Low recruitment Actual 6
NCT02783157 Terminated Transcutaneous Autonomic Modulation in Thoracic Surgery N/A Interventional Actual 2
NCT02907177 Terminated Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®) Phase 3 Interventional sponsor decision due to low recruitment Actual 136
NCT02927392 Suspended Brown Adipose Tissue Activity in Pre- and Postmenopausal Women N/A Interventional On hold due to COVID-19 outbreak Anticipated 72
NCT03719599 Suspended Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia Observational Due to the pandemic Anticipated 7500
NCT03114345 Terminated Correlation Between Pressure Differences and Micro-vascularization Changes in Bedridden Paraplegic Patient N/A Interventional Departure of the PhD in charge of the study Actual 4
NCT03136965 Suspended Platelet-Rich Plasma Therapy for Patellar Tendinopathy Phase 2 Interventional Suspended due to COVID-19 Anticipated 66
NCT03212170 Suspended FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer Phase 2 Interventional Suspended due to COVID-19 Anticipated 28
NCT03232151 Suspended C-arm Cone Beam CT Perfusion Guided Cerebrovascular Interventions N/A Interventional Suspended due to COVID-19 Anticipated 60
NCT03460483 Suspended Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care N/A Interventional Due to institutions restrictions Anticipated 700
NCT03486197 Suspended Neutron Radiation Therapy and Pembrolizumab in Treating Participants With Advanced Urothelial Carcinoma Phase 2 Interventional COVID19 Suspension Anticipated 20
NCT04080752 Suspended A Study of JNJ-61393215 in the Treatment of Depression Phase 2 Interventional Temporary suspension of screening/Enrollment due to worldwide COVID-19 pandemic Anticipated 218
NCT03524430 Suspended RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy BREVITY N/A Interventional Due to COVID-19 and/or protocol / protocol amendment review by EC/CA Anticipated 594
NCT03592368 Suspended Hostile Interpretation Bias Training to Treat Irritability N/A Interventional On hold due to COVID-19 outbreak. Anticipated 100
NCT03621761 Suspended Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue Phase 4 Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 330
NCT03674528 Suspended Technical Validation of MR Biomarkers of Obesity-Associated NAFLD Observational Suspended due to COVID-19 Anticipated 145
NCT04185051 Suspended A Study to Investigate the Effect of JNJ-67953964 on Gastric Mucosal Integrity in Healthy Male and Female Participants Phase 1 Interventional The recent outbreak and in anticipation of further spread of COVID-19, to protect the health and well-being of the study participants and site staff Anticipated 62
NCT03679624 Suspended Daratumumab Plus Ibrutinib in Patients With Waldenstrӧm's Macroglobulinemia Phase 2 Interventional Per IRB COVID‐19 guidance on conducting human subjects research. Anticipated 24
NCT03703492 Suspended Hybrid Molecular Imaging of ER in Breast Cancer Patients With DCIS Phase 2 Interventional Suspended due to COVID-19 Anticipated 34
NCT03723863 Suspended Occupational Therapist-Led Work Intervention in Facilitating Work Maintenance or Re-entry to the Workforce in Patients With Stage I to III Breast Cancer Undergoing Chemotherapy N/A Interventional COVID19 Suspension Anticipated 30
NCT04206488 Suspended A Study of JNJ-70033093 and Digoxin in Healthy Participants Phase 1 Interventional on hold due to precautionary measure taken due to the recent development in Europe with regards to the COVID-19 pandemic Anticipated 20
NCT03840733 Suspended Linking Temporal Patterns of Modifiable Behaviors to Weight Loss Outcomes Observational [Patient Registry] COVID-19 Anticipated 60
NCT03907046 Suspended Anticoagulation in ICH Survivors for Stroke Prevention and Recovery Phase 3 Interventional due to COVID-19 restrictions Anticipated 700
NCT03872102 Suspended Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging Observational The study is temporarily suspended due to guidelines received during the COVID-19 Pandemic. Anticipated 90
NCT03874793 Suspended Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD) N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions / interventions with current participants continue. This is not a suspension of IRB approval Anticipated 60
NCT03874845 Suspended Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)_VA Only N/A Interventional Enrollment is temporarily paused due to COVID-19 and is expected to reopen in the future. This is not a suspension of IRB approval. Anticipated 60
NCT03945630 Suspended Quadratus Lumborum Block in Total Hip Arthroplasty - Effect on Analgesia and Early Physiotherapy N/A Interventional unable to recruit patients due to COVID19 Anticipated 62
NCT03948776 Suspended Body Composition Ultrasound for Patients With Heart Failure Observational COVID-19 Anticipated 90
NCT04334018 Withdrawn Multi Point Pacing vs. Conventional STUDY PROTOCOL N/A Interventional Other studies on the same theme Actual 0
NCT04084509 Withdrawn Molecular and Functional Imaging in SNCA, Parkin and PINK1 Observational Change of circumstances for CI/PI. Actual 0
NCT04088994 Suspended Action Observation Based Rehabilitation of Children With Unilateral Cerebral Palsy N/A Interventional The study is suspended due to Covid-19 emergency Anticipated 24
NCT04095091 Suspended Real-time Tumor Localization and Guidance for Radiotherapy Using Ultrasound (US) and Magnetic Resonance (MR) Observational Suspended due to COVID-19 Anticipated 40
NCT04105218 Suspended Exercise, Sleep Quality and Nocturnal Fat Oxidation in Metabolic Syndrome N/A Interventional On hold due to COVID-19 outbreak Anticipated 18
NCT04141774 Suspended Stroke Rehabilitation Using Brain-Computer Interface (BCI) Technology N/A Interventional Suspended due to COVID-19 Anticipated 192
NCT04146363 Suspended Evaluation of the Efficacy and Safety of Lebrikizumab in Moderate to Severe Atopic Dermatitis Phase 3 Interventional Temporary enrollment suspension to manage patient safety due to COVID-19 Anticipated 400
NCT04178967 Suspended Evaluation of the Efficacy and Safety of Lebrikizumab in Moderate to Severe Atopic Dermatitis Phase 3 Interventional Temporary enrollment suspension to manage patient safety due to COVID-19 Anticipated 400
NCT04250337 Suspended Safety and Efficacy of Lebrikizumab in Combination With Topical Corticosteroid in Moderate to Severe Atopic Dermatitis. Phase 3 Interventional Temporary enrollment suspension to manage patient safety due to COVID-19 Anticipated 200
NCT04250350 Suspended Study to Assess the Safety and Efficacy of Lebrikizumab in Adolescent Patients With Moderate-to-Severe Atopic Dermatitis Phase 3 Interventional Temporary enrollment suspension to manage patient safety due to COVID-19 Anticipated 200
NCT04262115 Suspended Morning Versus Evening Exercise for Adults With Overweight and Obesity N/A Interventional COVID-19 Anticipated 40
NCT04336358 Suspended Telemedicine for First Trimester Abortion in South Africa N/A Interventional Due to COVID29 pandemic Anticipated 900
NCT04300907 Withdrawn An Open-Label Trial of PEMF Therapy [Provant Infinity Therapy System] for Home Use in Postoperative Pain N/A Interventional Due to COVID-19 Actual 0
NCT01333124 Terminated Preoperative Chemoradiotherapy With Gemcitabine for Resectable Pancreatic Carcinoma Phase 2 Interventional Recruitment delay Actual 23
NCT02098265 Suspended A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device N/A Interventional Suspended due to COVID-19 Anticipated 288
NCT02412046 Terminated Quantification of the Pressure Threshold Related to Tissue Injury in Bedriden Paraplegics N/A Interventional Departure of the PhD in charge of the study Actual 21
NCT02769806 Suspended Advanced Perfusion MRI of Treatment Response and Progression in Glioblastoma Observational Suspended due to COVID-19 Anticipated 25
NCT02773238 Suspended FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging Phase 2 Interventional COVID19 Suspension Anticipated 60
NCT02814318 Terminated Intrapartum Effect of Vancomycin on Rectovaginal GBS Colonization Observational Ancef (Cefazolin) became the new standard of care (instead of Vancomycin) for GBS prophylaxis if the patient is allergic to penicillin. Actual 41
NCT02881554 Suspended Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery N/A Interventional COVID19 Suspension Anticipated 60
NCT03696758 Suspended Improving Right Ventricular Function in Young Adults Born Preterm Phase 2 Interventional Due to COVID-19 Anticipated 10
NCT03709667 Suspended Exercise in Methamphetamine Use Disorder Upregulation and Neural Function Early Phase 1 Interventional Global pandemic Anticipated 90
NCT03869866 Suspended Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in Potential Pilgrims Aged 56 Years and Older in Turkey Phase 3 Interventional Suspended due to Covid-19 Anticipated 330
NCT03875326 Suspended Stimulation to Improve Memory N/A Interventional Enrollment and interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 240
NCT03877484 Suspended Evaluation of the Safety and Effectiveness of ALLEVYN Gentle Border Observational Temporarily suspended due to COVID-19 Anticipated 40
NCT03890367 Suspended Study of a Quadrivalent Meningococcal Conjugate Vaccine Compared With Two Meningococcal Reference Vaccines in Europeans Toddlers Phase 3 Interventional Suspended due to Covid-19 Anticipated 675
NCT03921398 Suspended Identifying New Therapeutic Targets for Lupus Treatment Observational [Patient Registry] "Owing to the Covid-19 epidemics