Clinical trials stopped by Covid-19

Benjamin Gregory Carlisle PhD

Charité – Universitätsmedizin Berlin, Germany
Berliner Institut für Gesundheitsforschung (BIG) / Berlin Institute of Health (BIH)
QUEST – Quality | Ethics | Open Science | Translation

The Covid-19 outbreak that became a global pandemic in 2020 has disrupted lives, families, industries and entire nations. This project is a daily-updated "living paper" that aims to quantify some of the effects of Covid-19 on the enterprise of human research.

The following table contains all registry entries from ClinicalTrials.gov whose overall status changed to Terminated, Suspended or Withdrawn since 2019-12-01. Investigator-provided reasons that explicitly mention Covid-19 are highlighted in green. Click a row of the table for more details about the trial.

To date, 1578 clinical trials have been stopped due to Covid-19.

These data and figures are available to be downloaded under a Creative Commons By-Attribution Non-Commercial license. This data set was last updated 2020-07-30.

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Covid-19 arm per-trial data set TSV
Comparator arm per-trial data set TSV
Drugs and biologics in stopped trials TSV
NCT ID Overall status Brief title Phase Study type Why stopped Enrollment
NCT02394106 Terminated Ofatumumab in Children With Drug Resistant Idiopathic Nephrotic Syndrome Phase 2 Interventional Actual 13
NCT02648971 Terminated Controlled Trial to Compare Single Versus Two Portal Knee Arthroscopy Techniques N/A Interventional Actual 37
NCT04249180 Withdrawn Eye Rubbing and Keratoconus in Montpellier CHU Observational CPP Actual 0
NCT04419493 Suspended A Study in Healthy Men to Compare 2 Different Formulations of Alteplase Phase 1 Interventional The study was put on hold after observation of unexpected laboratory findings. Root cause analysis is ongoing. Anticipated 60
NCT02926248 Suspended Effect of Colchicine on Range of Motion After Manipulation Under Anesthesia for the Stiff Total Knee Replacement Phase 4 Interventional Continuing IRB review was not submitted. Study was inactivated with the institutional IRB. Anticipated 112
NCT02654704 Terminated Vaccination Responses in Young and Older Adults Observational There was insufficient enrollment of subjects. Actual 61
NCT03511222 Terminated Vorolanib (X-82) Combined With Checkpoint Inhibitors in Patients With Solid Tumors Phase 1 Interventional Low accrual Actual 16
NCT03750773 Withdrawn Gabapentin for Relief of Immediate Postoperative Pain Phase 1/Phase 2 Interventional Lack of funding Actual 0
NCT03809130 Terminated Effectiveness of an Online Intervention Targeting Cancer-related Fatigue N/A Interventional Terminated Per PI Actual 27
NCT03876132 Terminated Perception of the Risks of Alcohol and Individual Vulnerabilities in Young Adults Observational The number of patients is suffisant to answer to the primary outcome Actual 23
NCT03881007 Terminated A Trial to Compare Antibacterial vs. Placebo Mouthwash to Reduce the Incidence of STIs in MSM Taking HIV PrEP N/A Interventional An interim analysis, planned because of the influence of the COVID-lockdown, showed the LCM mouthwash did not affect the incidence of Ng, Ct and syphilis. Actual 343
NCT03947437 Withdrawn Phase 1b/2a Trial to Evaluate LEP-F1 + GLA-SE in Healthy Adults and Leprosy Patients Phase 1/Phase 2 Interventional Finances Actual 0
NCT04013373 Suspended Home-Based Fluid Status Monitoring in Heart Failure Patients Observational Covid-19 pandemic Anticipated 200
NCT04038424 Suspended The Effect of Art Therapy on Patients With Stroke N/A Interventional Due to the Pandemic of COVID-19 Anticipated 60
NCT04248959 Suspended Prehabilitation to Improve Cancer Surgery Outcomes in AYA Patients With Extremity Sarcomas N/A Interventional COVID-19 Anticipated 30
NCT04290832 Terminated Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa N/A Interventional The study was stopped prematurely due to the COVID-19 pandemic Actual 317
NCT01715571 Terminated Assessment of Penile Vibratory Stimulation Using the Viberect in Men With Mild-Moderate ED N/A Interventional Unable to obtain adequate recruitment Actual 7
NCT02507232 Terminated Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas Early Phase 1 Interventional low enrollment Actual 2
NCT03013608 Terminated Children's Nail Bed Injuries : Study of the Efficacy of the Simple Relocation of Nail Plate N/A Interventional recruitment difficulty Actual 7
NCT03170583 Terminated SJM Brady MRI Post Approval Study Observational Abbott received FDA approval to transition the ongoing Brady MRI PAS study to EP a new EP-Passion Real World Evidence methodology Actual 1768
NCT03287180 Withdrawn Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use N/A Interventional unable to enroll any participants Actual 0
NCT03698370 Suspended Gallium Ga 68 DOTA-NeoBOMB1 and Gallium Ga 68 PSMA-R2 PET/MRI in Diagnosing Participants With Recurrent Prostate Cancer Phase 2 Interventional Due to Covid-19 issues Anticipated 50
NCT03831711 Suspended 68-Ga-RM2 PET/MRI in Imaging Patients With Estrogen Receptor-Positive Breast Cancer Phase 1/Phase 2 Interventional Due to Covid issues Anticipated 20
NCT03949517 Suspended A Pilot Study of 68-Ga PSMA 11 PET/MRI and 68-Ga RM2 PET/MRI for Evaluation of Prostate Cancer Response to HIFU or HDR Therapy Phase 1/Phase 2 Interventional Due to Covid Anticipated 10
NCT04105842 Suspended Refitting Daily Disposable Contact Lens Wearers With Dry Eye Disease With A Different Daily Disposable Lens Type N/A Interventional COVID-19 Anticipated 43
NCT04159935 Suspended Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease Phase 4 Interventional COVID-19 Anticipated 52
NCT04201639 Suspended Evaluating the Performance of Precision1 Daily Disposable Contact Lens in a Group of Heavy Digital Device Users N/A Interventional COVID-19 Anticipated 35
NCT04205162 Suspended Evaluating the Initial Lens Handling Experience of Neophyte Contact Lens Wearers Fitted With Precision1 and 1-Day Acuvue Moist Contact Lenses N/A Interventional COVID-19 Anticipated 60
NCT04209530 Suspended Impact of CCH Treatment of Buttock and Thigh Cellulite in Adult Women Phase 2 Interventional Study temporarily suspended due to COVID-19 related disruptions Anticipated 19
NCT04264208 Suspended HDR Brachytherapy 68-Ga-RM2 PET, 68-Ga-PSMA-11 PET &Multi Parametric MRI in Prostate Cancer Phase 2 Interventional Due to Covid Issues Anticipated 100
NCT04322903 Withdrawn Passport to Freedom: Health and Housing N/A Interventional Due to COVID 19 restrictions and protocol could not to be implemented safely for participants and researchers. Actual 0
NCT04490863 Suspended Noninvasive Hemoglobin Repeatability and Reproducibility in a Blood Donation Setting N/A Interventional Enrollment paused due to Covid-19 pandemic Anticipated 26
NCT02904876 Terminated Evaluation of Early Changes Visible to the Diffusion MRI in Response to Two Years of Treatment With Tysabri in Patients With Multiple Sclerosis Phase 4 Interventional Actual 70
NCT04114019 Withdrawn The Effect of Pelvic Floor Physiotherapy on Vaginal Elasticity Observational The study device became unavailable for use. Actual 0
NCT04140539 Suspended A Clinical Study to Enable Process Validation of Commercial Grade OTL-101 Phase 2/Phase 3 Interventional Recruitment on hold for business reasons Anticipated 3
NCT02269345 Terminated Auricular Acupuncture in Ureteral Stent Pain N/A Interventional Unworkable. This study had several PIs and attempted several avenues of recruitment. Still were only able to recruit 34 out of the 120 needed. Actual 34
NCT02608307 Terminated Medical Treatment Decision Making Using Adaptive Conjoint Analysis Observational Slow accrual and COVID-19 restrictions Actual 14
NCT02678351 Suspended 68Ga-PSMA-11 PET/MRI in Finding Tumors in Patients With Intermediate or High-Risk Prostate Cancer Undergoing Surgery Phase 2/Phase 3 Interventional Due to Covid-19 Anticipated 200
NCT02722512 Terminated Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine Phase 1 Interventional Lack of substantial evidence for immune responses in response to vaccination. Actual 10
NCT02749526 Terminated Endostar Combined With MPFC Adjuvant Treatment of Esophageal Cancer Clinical Trial Phase 2 Interventional low accrual rate Anticipated 70
NCT02959411 Terminated Tolvaptan for Advanced or Refractory Heart Failure Phase 4 Interventional Low accrual rate Actual 9
NCT03115840 Suspended Measuring Outcomes of Activity in Intensive Care Observational Study enrollment halted due to COVID-19 Anticipated 312
NCT03978390 Withdrawn Improving Children's Cooperation During Dental Injection N/A Interventional Change in research direction Actual 0
NCT04040127 Withdrawn Residual Dental Pulp Tissue and Cord Blood Stem Cells Phase 2 Interventional Did not obtain IRB approval Actual 0
NCT01798043 Terminated Impact of Septal Vs Apical Pacing on Right and Left Ventricular Performance N/A Interventional Due to slow enrolment Actual 29
NCT04136847 Withdrawn Study to Evaluate the Efficacy and Tolerability of the SkinPen on Male and Female Subjects' Dorsal Hands as a Treatment for Signs of Hand Aging N/A Interventional Due to COVID 19 the Study did not start enrolling Actual 0
NCT04285749 Withdrawn Prevention of Recurrence and Metastasis in Genetically High-Risk Melanomas Early Phase 1 Interventional PI moving to new institution prior to study activation Actual 0
NCT02727127 Terminated Brain Ion Homeostasis, Lithium and Bipolar Disorder Observational Lost funding due to low enrollment Actual 26
NCT02911467 Terminated Magnetic Resonance (MR) Imaging With Hyperpolarized Pyruvate (HP) (13C) in Castration-Resistant Prostate Cancer Phase 1 Interventional Low Accrual Actual 8
NCT03198156 Terminated Transcranial Direct Current Stimulation Therapy for Central Hypersomnia Without Cataplexy N/A Interventional Funding Stopped Actual 39
NCT03216538 Terminated Safety and Efficacy of AS101 1% Oral Solution in Patients With Neovascular Age-Related Macular Degeneration (AMD) Phase 1/Phase 2 Interventional Sponsor's decision. Actual 20
NCT03651531 Terminated Comparison of Insulin Alone to Insulin With Metformin to Treat Gestational Diabetes Mellitus Phase 3 Interventional Trial halted early due to limited ability to recruit participants Actual 1
NCT03822195 Withdrawn Lectine Pathway in Unstable Carotid Plaque Observational PI changed Institution Actual 0
NCT03839940 Suspended Dexamethasone in Reducing Everolimus-Induced Oral Stomatitis in Patients With Cancer Phase 3 Interventional New drug distribution process Anticipated 279
NCT03879044 Terminated Transcranial Direct Current Stimulation Therapy for Sleepiness Related to Shift Work Disorder (tDCS-SWORD) N/A Interventional Funding stopped Actual 16
NCT04034914 Terminated Yoga Intervention in Supporting Children With Cancer and Their Parents During Chemotherapy Infusion N/A Interventional Funding unavailable Actual 10
NCT01982149 Terminated Incorporation of Genetic Expression of Airway Epithelium With CT Screening for Lung Cancer Observational Lack of funding Actual 27
NCT04487548 Suspended Perioperative Smoking Cessation BUndle in Tertiary Care - Can Timing Improve OUTcomes? N/A Interventional COVID19 changed the workflow within the department and the study is no longer feasible Anticipated 214
NCT02188511 Terminated Effects of Electronic Cigarettes on Lung Biology N/A Interventional Lack of funding Actual 13
NCT02247648 Terminated Efficacy of Extended-release, Once Daily Tramadol for Post Operative Analgesia in Shoulder Arthroscopy Phase 2 Interventional Actual 100
NCT02531295 Suspended Immunologic Response to Kansui in Treated HIV+ Individuals: a Dose Escalation Study Phase 1 Interventional Temporary pause on non-COVID clinical trial recruitment at study site Anticipated 9
NCT02675218 Terminated Bone MicroArchitecture Abatacept (BMA2) Observational No more inclusion Actual 13
NCT02687477 Terminated PADN to Treat Severe Obstructive Sleep Apnea N/A Interventional Lack of patients meeting the criteria for admission Actual 1
NCT03390413 Withdrawn Robot-assisted Surgical Resection vs. Cryoablation of Localised Renal Cancer Phase 3 Interventional Logistics and lack of funding Actual 0
NCT03393117 Withdrawn Bupivacaine Versus Liposomal Bupivacaine For Breast Pain Management After Breast Recontruction Phase 2 Interventional No accrual Actual 0
NCT01652157 Terminated Long-term Study in US Cystic Fibrosis Patients Receiving Digestive Enzyme Supplements to Assess Narrowing of the Large Intestine Causing Adverse Intestinal Symptoms (Fibrosing Colonopathy) Observational Strategic considerations Actual 17
NCT02075047 Terminated Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder Phase 3 Interventional Based on recent input from FDA, the pre-specified final analysis will be performed at the current enrollment using a re-estimation of the sample size. Anticipated 194
NCT02180152 Withdrawn Postprandial Walking in Obese Pregnant Women and Perinatal Outcomes - a Multicenter Randomized Clinical Trial N/A Interventional Actual 0
NCT02717650 Suspended The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis. N/A Interventional Validation study suspended due to Covid-19 restrictions-will resume when able Anticipated 30
NCT02864355 Terminated Does Perioperative Goal Directed Therapy Using Flotrac Improve Outcomes in Esophagectomy Patients N/A Interventional Minimally invasive surgical methods have ceased enrollment Actual 35
NCT03067480 Terminated Comparison of 3 Versus 6-Month Use of CGMS in Non-Insulin Using T2DM Patients N/A Interventional Low enrollment Actual 12
NCT03128580 Terminated Embryo Aneuploidies and Morphokinetics in Ovarian Stimulated and Non Stimulated IVF Cycles Observational After an interim analysis, it was decided to discontinue the study after a stochastic curtailment analysis. Actual 40
NCT03324516 Withdrawn The Effect of Temporal Muscle Suspension of Temporal Hollowing N/A Interventional Due to limited support staff and time, study was unable to get started Actual 0
NCT03331666 Terminated Impact of LDL-cholesterol Lowering on Platelet Activation Phase 4 Interventional Terminated Prematurely due to COVID-19 Actual 4
NCT03341143 Suspended Fecal Microbiota Transplant (FMT) in Melanoma Patients Phase 2 Interventional Study suspended due to COVID 19. Study recruitment estimated to resume by September, 2020. Anticipated 20
NCT03586778 Suspended Dry Needling for Patients With Back Pain N/A Interventional COVID-19 Anticipated 48
NCT03730896 Terminated Effectiveness of Dry Needling of the Sternocleidomastoid in Patients With Cervicogenic Headaches N/A Interventional Not enough viable subjects Actual 17
NCT03930225 Suspended Effectiveness of A Stigma Directed Interventional Program in Schizophrenia N/A Interventional Covid 19 Break has caused the research to stop temporarily for safety of participants and conductors Anticipated 160
NCT03993379 Terminated PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors Phase 2 Interventional Sponsor's Decision Actual 3
NCT04059653 Terminated Evaluation of a New Technology for the Treatment of Bladder Leakage in Women N/A Interventional COVID19 pandemic. Cannot recruit from primary care during pandemic Actual 86
NCT04199481 Withdrawn Univation XM France Observational Study stopped due to product discontinuation by manufacturer Actual 0
NCT02662634 Withdrawn A Safety and Feasibility Study of AGS-003-LNG for the Treatment of Stage 3 Non Small Cell Lung Cancer Phase 2 Interventional Actual 0
NCT03304990 Withdrawn Panomics Relationships in the Epidemiology of Cancer Through In Silico Expression (PRECISE) Observational [Patient Registry] PI has left our Inst. Actual 0
NCT03513458 Withdrawn Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation Phase 1/Phase 2 Interventional [The risk of inhaled allergen challenge and anakinra treatment outweigh benefits to participants with allergic asthma due to the COVID-19 pandemic. Actual 0
NCT03513471 Withdrawn Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation Phase 1/Phase 2 Interventional The risk of inhaled allergen challenge and anakinra treatment outweigh benefits to participants with allergic asthma due to the COVID-19 pandemic. Actual 0
NCT03652298 Terminated Effects of a Neuroscience-based Technique on Cancer Patients Announced of a Palliative Disease Progression and Partners Phase 2 Interventional Lack of recruitment and of study staff Actual 19
NCT03663790 Suspended Effects of Gait Retraining on Lower Extremity Biomechanics N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 51
NCT03676712 Terminated The Effect of Flexible Thoracolumbar Brace on Idiopathic Scoliosis, Prospective, Randomized, Open-label Trial N/A Interventional Recruitment of subjects was not successful. Actual 17
NCT03687476 Withdrawn Safety and Tolerability Study of VTS-270 in Pediatric Participants With Niemann-Pick Type C (NPC) Disease Phase 2 Interventional Business decision to Cancel Actual 0
NCT03776864 Suspended Umbralisib and Pembrolizumab in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma Phase 2 Interventional Unacceptable Toxicity Anticipated 20
NCT03864393 Suspended Effect of Multimodal Exercise Training on Walking Economy in Individuals With Parkinson's Disease N/A Interventional Paused due to COVID-19. Expected to resume. Not a suspension of IRB approval. Anticipated 30
NCT03872336 Terminated Acute Labetalol Use in Preeclampsia Phase 4 Interventional Slow enrollment Actual 15
NCT03877692 Terminated Acute Control of Chronic Hypertension Phase 4 Interventional Slow enrollment Actual 10
NCT04023721 Terminated Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor Phase 2 Interventional Safety Actual 64
NCT04248361 Suspended TEM-PCR™ Prospective Clinical Utility Study Phase 4 Interventional COVID-19 Anticipated 314
NCT03239951 Terminated Study to Assess the Efficacy, Safety and Tolerability of (iTind) N/A Interventional Due to the COVID-19 outbreak and the overall low recruitment Actual 5
NCT03588936 Terminated Nivolumab and Tocilizumab for Relapsed Hematological Malignancy Post-allogeneic Transplant Phase 1 Interventional Halted for convenience due to COVID19 challenges. Actual 2
NCT03955718 Withdrawn Developing and Testing Motherly App: a Smartphone Application to Promote Mothers' Mental Health N/A Interventional The study stopped because of delays in the development of the smartphone app intervention Actual 0
NCT03234387 Suspended A CFit Study - Baseline Observational Poor recruitment Anticipated 45
NCT03237767 Suspended A CFit Study - Acute Exercise N/A Interventional Poor recruitment Anticipated 16
NCT02651116 Terminated Dextromethorphan Pediatric Acute Cough Study Phase 4 Interventional The study was prematurely discontinued due to slow enrollment during the 2019/2020 cold season. No safety or efficacy concerns led to the decision to terminate Actual 131
NCT03545165 Terminated 177Lu−J591 and 177Lu−PSMA−617 Combination for mCRPC Phase 1/Phase 2 Interventional Sponsor withdrawal Actual 6
NCT03586934 Terminated Multimodal Analgesia in Shoulder Arthroplasty Phase 3 Interventional Difficult to enroll patients for the study Actual 18
NCT03607864 Terminated Coral Bone Graft Verses Xenograft With Immediate Implant in Maxillary Anterior Esthetic Zone N/A Interventional because bone osteointegration is completed Actual 18
NCT03978416 Terminated Development of Novel Behavioral Intervention for Sustainable Weight Loss in Hispanic Adults With Obesity N/A Interventional The study was terminated due to the SARS-CoV-2 pandemic. Aim 1 was completed. Actual 23
NCT04277442 Suspended Testing Nivolumab in Combination With Decitabine and Venetoclax in Patients With Newly Diagnosed TP53 Gene Mutated Acute Myeloid Leukemia Phase 1 Interventional Other - Pending amendment to address FDA comments Anticipated 13
NCT04439305 Withdrawn Testing Dasatinib as a Potential Targeted Treatment in Cancers With DDR2 Genetic Changes (MATCH-Subprotocol X) Phase 2 Interventional zero accrual Actual 0
NCT02781961 Terminated Identification of In-vivo Probe Based Confocal Laser Endomicroscopy Cellular Characteristics in Obese Women Observational Actual 10
NCT03632954 Terminated Cytal® Wound Matrix and MicroMatrix® Wound Study Observational Sponsor Decision Actual 39
NCT04475861 Withdrawn Metabolomics and Wound Healing in Diabetes N/A Interventional no participants enrolled Actual 0
NCT00388739 Withdrawn Initiation of Chronic Asthma Care Regimens in the Pediatric Emergency Department N/A Interventional Different study was designed Actual 0
NCT03008980 Withdrawn The Analysis of WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) Increased Yield of Barrett's Esophagus and Esophageal Dysplasia Observational Study halted prematurely, prior to enrollment of first participant. Actual 0
NCT03214809 Terminated The Use of a Point-of-care Thoracic Ultrasound Protocol for Hospital Medical Emergency Teams N/A Interventional Slow inclusion rate (partly due to Covid-19) Actual 100
NCT03214835 Withdrawn CDx Biopsies for Detection of Laryngopharyngeal Reflux and Laryngeal Lesions N/A Interventional Study halted prematurely, prior to enrollment of first participant. Actual 0
NCT03399097 Withdrawn Characterizing the Intestinal Hormonal Secretion in Non-obese, Obese and Non-obese Patients After Bariatric Surgery Observational change sites Actual 0
NCT03414112 Suspended The Impact of Oxytocin on the Neurobiology of Anorexia Nervosa Early Phase 1 Interventional Recruitment is suspended due to COVID-19. Anticipated 40
NCT04043520 Suspended Bioenergetic Effects of Aging and Menopause (BEAM) Phase 4 Interventional COVID-19 Closure Anticipated 95
NCT04231188 Terminated User Experience of a Mobile Application Observational Delay in recruitment due to corona virus pandemic resulted in a newer version of mobile app made available and testing on the old version will be redundant. Actual 6
NCT04298814 Withdrawn Safety Related Factors of Endotracheal Intubation in Patients With Severe Covid-19 Pneumonia Observational It was repeated with other studies in the same department Actual 0
NCT04477642 Withdrawn Abatacept for Patients With COVID-19 and Respiratory Distress Phase 1/Phase 2 Interventional Funding Actual 0
NCT02798939 Terminated Evaluation of Lactoferrin, Procalcitonin and Aution® Urine Dipsticks for the Diagnosis of Spontaneous Bacterial Peritonitis in Cirrhotic Patients Observational investigator choice Actual 123
NCT02819544 Withdrawn Evaluation of the Interest of the Instillation of Saline Intraperitoneally (INSI ) Versus Instillation of Naropin the Surgical Site Versus Lung Recruitment Maneuvers ( PVM ) in the Management of Pain After Laparoscopic Cholecystectomy in Ambulatory Care Phase 3 Interventional investigator choice Actual 0
NCT02828800 Terminated Cartography of Allodynic and Hypoasthetic Territories Following TKA Observational investigator choice Actual 38
NCT03132818 Withdrawn Impact of the Assumption in Charge of Medical Aid to the Procreation With Donation of Gametes on the Sexuality of the Couple Observational investigator choice Actual 0
NCT03145870 Withdrawn Prevalence of Asymptomatic Thrombosis in Multiple Myeloma N/A Interventional investigator choice Actual 0
NCT03149952 Withdrawn A Pilot Study of the Feasibility of Setting up a Logbook for Allogeneic Haematopoietic Stem Cell Patients at the University Hospital of Amiens N/A Interventional investigator choice Actual 0
NCT03295656 Withdrawn Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis Phase 1 Interventional Unanticipated delays. Actual 0
NCT03342638 Terminated Maximizing Outcome of Multiple Sclerosis Transplantation Phase 3 Interventional PI Sabbatical Actual 66
NCT03537521 Withdrawn Reversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists (RADOA). Focus on New Antidots Observational [Patient Registry] due to corona pandemic crisis Actual 0
NCT03696901 Terminated Xydalba Utilization Registry in Germany Observational Terminated Actual 16
NCT03797430 Withdrawn Determination of Normal Values for the Star Excursion Balance Test (SEBT) in Handball Players Observational NO PARTICIPANTS ENROLLED Actual 0
NCT03983486 Withdrawn Rationale for Cytogenetic Risk Stratification by Imaging Flow Cytometry in Multiple Myeloma Observational technical problem Actual 0
NCT04192513 Suspended Observer-Blinded Dose Escalating, Single Dose to Study Safety and Antimicrobial Efficacy of Gel vs. Placebo Phase 2 Interventional Covid-19 has shut the clinic indefinitely Anticipated 12
NCT04315051 Suspended A Trial of Safety/Efficacy of Test Article in Patients With Interdigital T. Pedis Phase 2 Interventional Covid- 19 has shut the clinic Anticipated 80
NCT04345614 Suspended A Study of Auxora in Patients With Severe COVID-19 Pneumonia Phase 2 Interventional FDA strongly recommended transitioning to blinded, placebo-controlled RCT. Anticipated 400
NCT02032784 Terminated Prophylactic Octreotide to Prevent Post Duodenal EMR and Ampullectomy Bleeding Phase 4 Interventional Difficult to enroll subjects Actual 33
NCT03809650 Terminated A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH). Phase 3 Interventional Due to a change in the development strategy Actual 9
NCT03910790 Withdrawn Liver Biopsy Using a 19 Gauge Fine Needle Biopsy Needle N/A Interventional A competing study made it challenging to enroll subjects. Actual 0
NCT02333409 Terminated Acupuncture for Pain Control in Patients With Inoperable Pancreatic Cancer N/A Interventional Expertise resigned Actual 1
NCT03303690 Terminated AS: Ankle Spacer for Talar Osteochondral Defects N/A Interventional Arthrex stopped manufacturing the device Actual 2
NCT03676725 Suspended Assessing the Frequency of Lidocaine Ineffectiveness in the General Population Early Phase 1 Interventional Pandemic (Covid-19) Anticipated 100
NCT04167189 Suspended Assessing the Frequency of Lidocaine Ineffectiveness in ADHD Early Phase 1 Interventional Pandemic (Covid 19) Anticipated 40
NCT04411134 Withdrawn E7 TCR T Cell Immunotherapy for High-Grade Cervical Intraepithelial Neoplasia Phase 1 Interventional Closed based on the lack of perceived clinical activity observed from a different study treating a similar patient population with same study agent. Actual 0
NCT00992030 Terminated R-ABVD vs ABVD-RT in Early Stage Hodgkin's Lymphoma Phase 3 Interventional Low recruitment and difficulty in having study data Actual 112
NCT01113567 Suspended Effect of Lactose in Patients With Chronic Liver Disease and Minimal Hepatic Encephalopathy N/A Interventional The hospital was converte to attend only COVID19 patiens Actual 18
NCT01518959 Terminated The Effect of 25-OH-Vitamin-D3 Substitution in Patients With Malignant and Immune-hematologic Diseases Phase 3 Interventional Insufficient recruitment rate; technical issues with sample storage Actual 31
NCT02439307 Suspended Effycacy of Rifaximin on Reverse Minimal Hepatic Encephalopathy and Elimation Small Intestinal Bacterial N/A Interventional The hospital was converted to attend only covid19 patients Anticipated 46
NCT02547948 Withdrawn CD19-targeting CAR T Cells for B Cell Lymphoma Phase 1/Phase 2 Interventional Actual 0
NCT02547961 Withdrawn Chimeric Antigen Receptor-Modified T Cells for Breast Cancer Phase 1/Phase 2 Interventional Project terminated due to revision of local regulations Actual 0
NCT02565901 Terminated Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Phase 1/Phase 2 Interventional Terminated due to insufficient funding Actual 28
NCT02575261 Withdrawn CAR-T Cell Immunotherapy for EphA2 Positive Malignant Glioma Patients Phase 1/Phase 2 Interventional Actual 0
NCT02712905 Terminated An Open-Label, Dose-Escalation/Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced Malignancies Phase 1/Phase 2 Interventional Strategic Business Decision Actual 116
NCT02723942 Withdrawn CAR-T Cell Immunotherapy for HCC Targeting GPC3 Phase 1/Phase 2 Interventional Project terminated due to revision of local regulations Actual 0
NCT02732015 Terminated Rolapitant Hydrochloride in Preventing Nausea/Vomiting in Patients With Sarcoma Receiving Chemotherapy Phase 2 Interventional Terminated per PI's request Actual 37
NCT03252171 Withdrawn CAR-T Cell Immunotherapy for GD2 Positive Glioma Patients Phase 1/Phase 2 Interventional Project terminated due to revision of local regulations Actual 0
NCT03259659 Terminated Autonomic and Cytokines Profiles of Patients With Ulcerative Proctitis Observational [Patient Registry] Principal Investigator was leaving the institution. Actual 20
NCT03439150 Terminated Resistance STEMI Study N/A Interventional slow enrolment Actual 5
NCT03445663 Terminated Study Evaluating AMG 424 in Subjects With Multiple Myeloma Phase 1 Interventional Sponsor business decision not to proceed with the AMG 424 asset. Actual 27
NCT03514407 Terminated A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma Phase 1 Interventional Strategic Business Decision Actual 25
NCT03621124 Suspended Maladaptive Adipose Tissue Activity in Cancer N/A Interventional Pause due to COVID-19 Pandemic Anticipated 36
NCT03669549 Terminated Nevanimibe HCl for the Treatment of Classic CAH Phase 2 Interventional Following an interim data review, further investment in nevanimibe has been discontinued Actual 15
NCT03755960 Suspended ACUpuncture in Diabetic Peripheral Neuropathy N/A Interventional due to the pandemic clin.research was suspended from 04/2020 on- tbc in 09/2020 Anticipated 110
NCT03862846 Terminated A Study of the Safety of REN001 in Patients With Primary Mitochondrial Myopathy Phase 1 Interventional COVID-19 Pandemic sufficient data gathered to achieve the study objective Actual 23
NCT04088032 Withdrawn Neoadjuvant Study of Abemaciclib, Durvalumab, and an Aromatase Inhibitor Early Stage Breast Cancer Early Phase 1 Interventional Per sponsor Actual 0
NCT04135768 Withdrawn A Study Examining The Effect Of Wrist Joint Haematoma Washout As An Adjunct Procedure To Plating Of The Distal Radius In Fractures Of The Distal Radius Involving The Wrist Joint N/A Interventional COVID19 pandemic: national lockdown imposed and study centre diverted all trauma cases to surrounding hospitals Actual 0
NCT04176978 Suspended PsA T2T Statin Trial on Carotid and Coronary Atherosclerosis N/A Interventional Lack of funding Anticipated 142
NCT04476693 Suspended Metabolic Responses to Breakfast in Adolescent Girls N/A Interventional Unable to recruit due to school closures in response to Covid-19 Anticipated 18
NCT02894086 Withdrawn A Retrospective Study of the Feasibility of Ambulatory Appendicectomy for Acute Appendicitis (Based on Data From the PMSI French National Hospital Information System) in the Adults Hospitalized Between December 2013 and December 2014 Observational Investigator choice Actual 0
NCT02973009 Withdrawn Impact of the Systematic Closure of the Epigastric Trocar on Postoperative Incisional Hernia After Sleeve Gastrectomy Rate of First Intention. Monocentric Study, Before / After Prospective. Observational investigator choice Actual 0
NCT03004482 Suspended Analysis of Video Imaging in Newborns Observational lack of Funding Anticipated 80
NCT03027934 Withdrawn A Single Center Study to Evaluate Ticagrelor Mechanism of Action in Inhibiting Juvenile Platelet ADP Response Phase 4 Interventional Study population difficult to recruit Actual 0
NCT03079661 Terminated Impact of Air Quality on Exacerbations of COPD in the Somme Observational investigator choice Actual 179
NCT03107390 Terminated Evaluation of NT-proBNP in Chronic Inflammatory Bowel Disease N/A Interventional investigator choice Actual 159
NCT03115138 Terminated Evaluation of Circulating Tumor DNA as a Theranostic Marker in the Management of Glioblastomas. N/A Interventional investigator choice Actual 19
NCT03139825 Withdrawn Connectivity and Social Cognition in Adolescent Girls With Borderline Personality Disorder, a Pilot Study N/A Interventional Not accepted Actual 0
NCT03144661 Terminated An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies Phase 1 Interventional Strategic Business Decision Actual 25
NCT03311074 Withdrawn Retroviral Insertion Site Methodology Study Phase 4 Interventional Replaced with new observational study design Actual 0
NCT03407976 Terminated Apatinib With Pembrolizumab in Previously Treated Advanced Malignancies Phase 1 Interventional Funding source withdrew financial support prior to start of Phase II portion of study Actual 5
NCT03602872 Withdrawn Safety of Allogeneic Bone Marrow Derived Mesenchymal Stem Cells in Subjects With Osteoarthritis Phase 1 Interventional Sponsor to start with different protocol, postponed due to COVID Actual 0
NCT03647085 Suspended Data Collection Atrial Fibrillation Exploratory Study Observational Due to COVID-19 Anticipated 50
NCT03698227 Terminated OlaReDo - Olaratumab and Rechallenge With Doxorubicin in Soft Tissue Sarcoma Patients Phase 2 Interventional Lack of efficacy on olaratumab Actual 2
NCT03721393 Suspended Data Collection - Of Syncope Tilt Table Testing Study Observational Due to COVID-19, part of the budget used to fund the COST3 trial has been eliminated. The study will start again in the near future. Anticipated 50
NCT03847675 Suspended Reach Out and Read Arabic to Promote Arabic Literacy in Toddlers N/A Interventional Awaiting IRB approval of amendment Anticipated 206
NCT04049682 Withdrawn Start Times and Restful Sleep Observational Study never recruited subjects Actual 0
NCT04101890 Suspended The Healthy Baby Bottoms Study Phase 4 Interventional Pandemic preventing recruitment due to regulations limiting personnel in clinical spaces. Anticipated 100
NCT04150666 Withdrawn The Water Intake Trail and Primary Aldosteronism Postoperation(WIT-PAP) N/A Interventional No subjects are willing to participating. Actual 0
NCT04272645 Withdrawn Abemaciclib With or Without Atezolizumab in Metastatic Castration Resistant Prostate Cancer Phase 2 Interventional Coordinating site change Actual 0
NCT04293172 Withdrawn Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease. Phase 3 Interventional Study halted prematurely, prior to enrolment of first patient. Actual 0
NCT04331834 Suspended Pre-Exposure Prophylaxis With Hydroxychloroquine for High-Risk Healthcare Workers During the COVID-19 Pandemic Phase 3 Interventional The study has been suspended until a new epidemic curve occurs. Anticipated 440
NCT04474652 Suspended Guide for Prioritisation of Patients for Referral to Breast Clinics Observational COVID-19 Anticipated 4000
NCT04474795 Suspended Clinic to Community Connections N/A Interventional due to COVID-19 Anticipated 115
NCT02193152 Terminated Pazopanib in Molecularly Selected Patients With Advanced NSCLC Phase 2 Interventional Terminated by sponsor Actual 16
NCT03090126 Withdrawn Assessment of Therapeutic Education About Non Invasive Ventilation in Patients With Chronic Respiratory Failure (QoVNI) Observational No possibility to recruit. Actual 0
NCT03285165 Suspended Cerebral Vascular Effects of Dexmedetomidine Versus Propofol Sedation in Intubated Mechanically Ventilated ICU Patients Phase 2/Phase 3 Interventional NO AVAILABLE FUND Anticipated 60
NCT02050607 Withdrawn Fecal Microbiota Transplantation for the Treatment of Metabolic Syndrome Phase 2 Interventional Actual 0
NCT02078934 Withdrawn Endoscopic Gastric Plication for Weight Loss in Morbidly Obese Patients Prior to Incisional Hernia Repair N/A Interventional Did not receive funding for recruitment. Actual 0
NCT02418039 Suspended High Protein Diet Versus Normal Protein Diet in Treating Patients With Minimal Hepatic Encephalopathy N/A Interventional The hospital was convert to attend only COVID19 Anticipated 80
NCT02752230 Withdrawn Comparison of Exparel to Marcaine in Post-Surgical Analgesia in Bariatrics Phase 4 Interventional Attending physician left network Actual 0
NCT02814344 Terminated Comparative Study of the Propagation of Uterine Electrical Activity (EHG) in Pregnant Women During Pregnancy and During Labour Observational Investigator choice Actual 27
NCT02815501 Withdrawn Thyroid Dysfunction and Obstetric Complications Observational Investigator choice Actual 0
NCT02848508 Withdrawn Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up Study Phase 2 Interventional Investigator choice Actual 0
NCT02281994 Terminated Odontoid Fracture Study Treated With Pulsed Electromagnetic Fields N/A Interventional Anticipated 360
NCT02436590 Terminated Efficacy and Safety of an Active Pulsed Electromagnetic Field for the Treatment of Osteoarthritis of the Knee N/A Interventional Anticipated 150
NCT02453490 Terminated Compare Efficacy and Safety of Raltitrexed-based and 5fu-based Neoadjuvant Chemotherapy for Colorectal Liver Metastasis Phase 3 Interventional difficultly recruiting Anticipated 360
NCT03253679 Suspended AZD1775 in Treating Patients With Advanced Refractory Solid Tumors With CCNE1 Amplification Phase 2 Interventional Other - Protocol amendment required for expansion Anticipated 32
NCT04272034 Withdrawn Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors Phase 1 Interventional Business Decision Actual 0
NCT03686176 Terminated Virtual Reality During Procedures in Pediatric Patients N/A Interventional Coronavirus (COVID-19)-related pause on all clinical research studies. Actual 64
NCT04471857 Terminated Hypnosis for Children Undergoing Anorectal Manometry N/A Interventional Due to COVID-19 recruitement stopped since intended sample size was an estimation and not based on power calculation Actual 34
NCT04472520 Withdrawn Use of AliveCor ECG Monitoring to Replicate ECG Lead Recording N/A Interventional lack of enrollment Actual 0
NCT02903407 Terminated Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU Phase 4 Interventional All enrolled participants completed the study protocol but the study was terminated prior to the goal number of participants due to low recruitment Actual 7
NCT04265014 Withdrawn Comparison of Goal-directed and Liberal Fluid Management N/A Interventional we didn't have any patient Actual 0
NCT04468373 Terminated Study of WA-NG (NG-IMT) Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration N/A Interventional Development of next-generation device Actual 9
NCT04468854 Terminated Influence of Luteolin on Memory in Healthy Subjects N/A Interventional Corona-Virus Lockdown (16th March in Switzerland) Actual 40
NCT00003086 Terminated Repeated Bone Marrow Transplantation in Treating Women With Advanced Breast Cancer Phase 1/Phase 2 Interventional no participants enrolled in a three year period Anticipated 12
NCT02527681 Terminated Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibiotics Phase 1 Interventional on 07Jul2020 due to slow enrollment; there were no safety concerns. Actual 15
NCT03225924 Terminated Study of Entospletinib (ENTO) in Newly Diagnosed DLBCL Patients With aaIPI>=1 Treated by Chemiotherapy Phase 1/Phase 2 Interventional Stop of drug development Actual 25
NCT03380091 Terminated Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial Phase 4 Interventional Recruitment challenges Actual 3
NCT03518320 Terminated Safety and Tolerability of TAR-200 and Nivolumab in Subjects With Muscle-Invasive Bladder Cancer Phase 1 Interventional Business objectives have changed Actual 13
NCT03661983 Terminated Trial to Evaluate the Long-term Efficacy of Oral Aripiprazole in the Treatment of Pediatric Subjects With Tourette's Disorder Phase 4 Interventional Lack of feasibility for completion of the trial within a reasonable time frame. Actual 36
NCT03672474 Terminated REGEnLIFE RGn530 - Feasibility Pilot N/A Interventional Covid19 sanitary crisis Actual 60
NCT03781089 Suspended Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients Phase 4 Interventional Covid-19 Anticipated 40
NCT04032483 Suspended A Survey of Financial Toxicity in Rural Cancer Patients Observational Study recruitment temporarily halted due to COVID-19. Anticipated 100
NCT04055012 Suspended Effects of Metformin on Low Back Pain Phase 2 Interventional FDA Recall of Metformin Anticipated 400
NCT04127695 Withdrawn A Study to Evaluate the Safety and Tolerability of ABBV-0805 in Patients With Parkinson's Disease Phase 1 Interventional Strategic considerations Actual 0
NCT04223011 Withdrawn Initiating Substance Use Disorder Treatment for Hospitalized Alcohol Use Disorder Patients N/A Interventional Due to COVID-19, recruitment was halted before we were able to enroll participants. Currently we are unable to resume recruitment due to study staff changes. Actual 0
NCT04392648 Withdrawn A Study to Evaluate the Safety, Tolerability and Efficacy of Intravenous TAK-573 as Part of Combination Therapy in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) Phase 1 Interventional Business Decision (no enrollment) Actual 0
NCT02741505 Withdrawn Brain Sleep Deprivation MRI Effects (BEDTIME) N/A Interventional Funding was not obtained Actual 0
NCT02851056 Suspended Survivin Vaccine : Multiple Myeloma Autologous Hematopoietic Cell Transplant (HCT) Early Phase 1 Interventional Temporary lack of funding Anticipated 20
NCT03231527 Withdrawn Outcomes of Total Arterial Coronary Artery Bypass Grafting Observational research group's decision Actual 0
NCT03330834 Terminated CAR-T Cell Immunotherapy for Advanced Lung Cancer Phase 1 Interventional Serious adverse events Actual 1
NCT03461861 Suspended Network-Level Mechanisms for Preclinical Alzheimer's Disease Development Phase 2 Interventional COVID-19 Anticipated 50
NCT03797612 Withdrawn Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Knee Replacement in Patients With High PCS Scores Phase 2 Interventional Study initiation delayed due to COVID 19 Actual 0
NCT03878563 Terminated Alterations in Intestinal Mucosal Barrier Visualized by Confocal Laser Endomicroscopy in Liver Cirrhosis: a Pilot Trial (AMBIC) Observational Sponsor-PI left Switzerland Actual 26
NCT04104919 Withdrawn Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores Phase 2 Interventional Study Initiation delayed due to COVID 19 Actual 0
NCT04138199 Terminated A Study to Assess Effectiveness and Safety of Fixed Dose Combination of Lopinavir/Ritonavir (LPV/r) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Patients After Switching From Kaletra in the Routine Clinical Settings of Russian Federation Observational Strategic Considerations Actual 239
NCT04235621 Suspended A Study to Understand the Genetics and Clinical Course of Focal Segmental Glomerulosclerosis (FSGS), Treatment-Resistant Minimal Change Disease (TR-MCD), and Diabetic Nephropathy (DN) Observational Sponsor decision for administrative reasons Anticipated 160
NCT04379947 Withdrawn Preoperative Use of Fractional Flow Reserve in CABG Use and Effectiveness of FFR-based CABG in Real-life Practice Observational research group's decision Actual 0
NCT00820716 Terminated Exercise Training in Asthma N/A Interventional Difficulties in recruiting patient Actual 2
NCT02050646 Suspended The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune Hepatitis N/A Interventional Study PI changed institutions Actual 20
NCT02056054 Suspended De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation Observational Study PI has moved institutions Anticipated 180
NCT03361085 Terminated Modular Prevention Bundle for Non-ventilator-associated Hospital-acquired Pneumonia (nvHAP) N/A Interventional COVID-Epidemic with changes in patient mix, restructuring of wards/departments, new standard-precautions Actual 45000
NCT03653533 Terminated Evaluation of the Function "Stop Before Hypoglycemia" on External Insulin Pump N/A Interventional Difficulties for recruitment Actual 8
NCT01705080 Terminated IntErnational Long-term Follow-up Study of Patients With Uncontrolled HyperTensioN Observational Abbott made a decision to not further develop the RDN program. Actual 354
NCT03819933 Suspended Optimizing Family Counseling for Anticipated Extremely Preterm Delivery N/A Interventional Study has temporarily suspended enrollment due to the Covid-19 pandemic. Anticipated 460
NCT01988090 Terminated High Dose Vitamin D vs Standard Dose Vitamin D Study Phase 2 Interventional An interim analysis demonstrated no benefit of high dose vitamin D when compared to standard dose vitamin D in the reduction or prevention of arthralgia Actual 93
NCT02412371 Terminated A Study Evaluating the Efficacy and Tolerability of Veliparib in Combination With Paclitaxel/Carboplatin-Based Chemoradiotherapy Followed by Veliparib and Paclitaxel/Carboplatin Consolidation in Adults With Stage III Non-Small Cell Lung Cancer (NSCLC) Phase 1/Phase 2 Interventional Phase 2 was not conducted due to a change in the standard of care for newly diagnosed, unresectable Stage III NSCLC Actual 48
NCT04467632 Withdrawn Circadian & Homeostatic Synchronization Effect on Waking Mobility in Parkinson's Disease N/A Interventional The principal investigator left the hospital Actual 0
NCT02899156 Terminated Flumazenil for Hypoactive Delirium Secondary to Benzodiazepine Exposure Phase 4 Interventional A planned interim analysis led to the trial being stopped early based on the observed size effect and power analysis. Actual 22
NCT01757899 Withdrawn Effects and Safety of Infusion of Low-Doses of Methylprednisolone in Early ALI and ARDS in Children Phase 2 Interventional Technical problems Actual 0
NCT02174770 Terminated Blood Flow Restriction Training in Rehabilitation Patients N/A Interventional Lack of resources Actual 10
NCT02227134 Withdrawn Ultrasound to Predict a Pediatric Difficult Airway and Obstructive Sleep Apnea Syndrome in Children N/A Interventional Unable to perform the ultrasound. Actual 0
NCT02323477 Terminated Human Umbilical Cord Stroma MSC in Myocardial Infarction Phase 1/Phase 2 Interventional Due to budget limitations as allocated for a given period. Actual 46
NCT02610608 Terminated Medical Assistance for the Procreation and Risk of Thrombosis. Observational RECRUITMENT DIFFICULTIES Actual 129
NCT02717507 Suspended Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors Phase 2 Interventional Evaluation of currently enrolled patients Anticipated 250
NCT02840513 Terminated Smartphone App and CO Self-monitoring for Smoking Cessation Phase 4 Interventional Due to insufficient patient recruitment and lack of funding Actual 81
NCT02887118 Terminated Dense Red Blood Cells in Sickle Cell Children Observational The recruiting centre was no longer presenting new patients for inclusion Actual 82
NCT02901431 Terminated A Study to Investigate the Efficacy and Safety of Balovaptan (RO5285119) in Participants With Autism Spectrum Disorder (ASD) Phase 2 Interventional The 24-week analysis indicated no clinical or statistical benefit for the primary endpoint for the overall study population. No new safety concerns identified. Anticipated 340
NCT03002506 Terminated Pharmacokinetics of Ceftolozane/Tazobactam in Patients With Burns Phase 4 Interventional Much slower recruitment than anticipated Actual 6
NCT03003728 Withdrawn 2015-10: Expanded Natural Killer Cells and Elotuzumab for High-Risk Myeloma Post- Autologous Stem Cell Transplant (ASCT) Phase 2 Interventional Withdrawal of study support Actual 0
NCT03321864 Suspended Capture of Prostatic Trans-rectal Ultrasound Scans for Research N/A Interventional PI has left Trust currently. Anticipated 150
NCT03430544 Suspended Cariprazine Effects on Brain and Behavior in Cocaine Use Disorder Phase 2 Interventional Suspended: Study halted prematurely but potentially will resume Anticipated 60
NCT03432572 Withdrawn Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets Early Phase 1 Interventional enrollment proved difficult Actual 0
NCT03573076 Terminated Treatment of Photodamaged Skin of the décolleté Phase 4 Interventional The second study arm including radio-frequency microneedling was withdrawn due to availability of newer treatment options. Actual 12
NCT03757351 Terminated Study to Evaluate DNL747 in Subjects With Amyotrophic Lateral Sclerosis Phase 1 Interventional Due to change in Sanofi's development strategy for DNL747/SAR443060 - not due to any safety concerns Actual 15
NCT03881995 Terminated Effects of Insulin Glargine and Lixisenatide on the Brain Phase 4 Interventional insufficient recruitment Actual 1
NCT03904706 Terminated Linking Facility-based Mortality Audits With Community Engagement in Gilgit-Baltistan, Pakistan N/A Interventional We were unable to continue field activities due to COVID-19 Actual 1871
NCT04085549 Suspended Effects of a Berry Oil Cream on Atopic Eczema and Skin N/A Interventional Study was suspended due to Covid-19 situation. Anticipated 90
NCT04090853 Terminated Subject Evaluation of a 1064nm Diode Laser/RF N/A Interventional Slow enrolment and Covid19 Actual 13
NCT04185155 Terminated Simple Cognitive Task After Trauma EKUT RCT N/A Interventional Halted prematurely - Covid-19 pandemic prevented recruitment/testing in ED Actual 16
NCT03444311 Terminated Combined Nutritional Therapies for the Treatment of Ulcerative Colitis N/A Interventional Low tolerability of fibers included in the product Actual 12
NCT04462341 Suspended Efficacy of an Oral Hygiene Implant Protocol N/A Interventional COVID-19 Anticipated 28
NCT01335113 Terminated A Scan Ultrasonography in the Evaluation of Retinopathy of Prematurity Observational Unable to get accurate measurements with existing technology Actual 1
NCT01551043 Terminated Allo CART-19 Protocol Phase 1 Interventional Administrative Reasons Actual 2
NCT01711307 Terminated Operative vs. Non-Operative Treatment of Acute Ruptures of the Achilles Tendon N/A Interventional Anticipated 220
NCT01823237 Suspended Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19 Anticipated 15
NCT02544503 Suspended Customized Cortical Stimulation Therapy in the Rehabilitation of Stroke Patients N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 150
NCT02565199 Suspended Premotor Cortex: A New Target for Stroke Motor Rehabilitation N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 50
NCT03460964 Terminated Measuring Sweat Glucose of Patients With Diabetes - The ENGAGE Study N/A Interventional Could not perform accurate measures due to equipment and sensor issues. Actual 2
NCT03504917 Terminated A Study of Balovaptan in Adults With Autism Spectrum Disorder With a 2-Year Open-Label Extension Phase 3 Interventional A futility analysis assessed that the study is highly unlikely to meet the pre-defined primary objective of the study. No new safety concerns were identified. Actual 322
NCT03609502 Suspended Perceptual Learning and Memory Consolidation in Adults With and Without LI N/A Interventional research facilities temporarily closed due to COVID-19 Anticipated 100
NCT03628053 Withdrawn Tisagenlecleucel vs Blinatumomab or Inotuzumab for Patients With Relapsed/Refractory B-cell Precursor Acute Lymphoblastic Leukemia Phase 3 Interventional Novartis is no longer pursuing this study because of planned investigation of novel CAR-T therapies in this patient population. Actual 0
NCT03685773 Suspended The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients Phase 2 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 60
NCT03714867 Withdrawn Pre-Operative Pregabalin for Post-Operative Pain in Head and Neck Cancer Surgery Phase 4 Interventional Inability to recruit patients Actual 0
NCT03869814 Withdrawn Non-invasive Liquid Biopsy Analysis of Epigenomics Signatures in Multiple Cancer Types Observational Developing new protocol Actual 0
NCT01445821 Terminated Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial Phase 3 Interventional Developed a better regimen: DIAD. Cast. 2018 NCT03593902 Actual 44
NCT03948464 Suspended Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder Phase 3 Interventional Temporarily suspended due to COVID-19 precautions Anticipated 198
NCT04060329 Terminated Measuring and Improving Coproduction Using coopeRATE N/A Interventional Reasons associated with COVID-19 pandemic led to cancellation of Phase 2 Actual 280
NCT04468048 Withdrawn Music Utilization in Sedation and Induction in Colonoscopy Observational No participants Actual 0
NCT04090242 Terminated Impact of App Based Diabetes Training Program in Conjunction With the BD Nano Pen Needle in People With T2 Diabetes N/A Interventional Enrollment halted prematurely due to the Covid-19 pandemic Actual 57
NCT04465071 Suspended Lubricating Eye Drops After Routine Cataract Surgery N/A Interventional No active recruitment at present due to COVID-19 pandemic Anticipated 168
NCT03209869 Suspended Treatment of Relapsed or Refractory Neuroblastoma With Expanded Haploidentical NK Cells and Hu14.18-IL2 Phase 1 Interventional resources limited due to COVID-19 Anticipated 6
NCT03265717 Terminated DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (hTERT), Invac-1 in Chronic Lymphocytic Leukemia Phase 2 Interventional sponsor decision Actual 26
NCT03281902 Suspended Genetic Analysis in Blood and Tumor Samples From Patients With Advanced or Metastatic Estrogen Receptor Positive and HER2 Negative Breast Cancer Receiving Palbociclib and Endocrine Therapy Observational Budget Anticipated 250
NCT03586414 Suspended MitoQ Supplementation and Cardiovascular Function in Healthy Men and Women N/A Interventional COVID-19 Anticipated 60
NCT03708380 Suspended Diabetes Prevention for Black Men N/A Interventional COVID-19 Anticipated 20
NCT03775915 Terminated Neurofeedback for Stroke Rehabilitation N/A Interventional COVID-19 lockdown and halt of clinical trials Actual 26
NCT04106505 Terminated Efficacy of a Novel App-based Migraine Treatment Platform - a Pilot Study N/A Interventional Recruitment terminated prematurely due to SARS-CoV-2 pandemic Actual 23
NCT02655861 Terminated A Multi-center, Prospective Evaluation of Infants and Children With Congenital Ichthyosis Observational Actual 21
NCT02695641 Withdrawn Reduction of Plasma Free VEGF-A Using Low-dose Bevacizumab in Hemodialysis Patients Early Phase 1 Interventional Unable to enroll patients for the trial. Actual 0
NCT02825446 Terminated Angioplasty of the Tibial Arteries Augmented Radio Frequency Denervation of the Popliteal Artery N/A Interventional a significant number of patients were not selected Actual 15
NCT02959502 Suspended Home-Based CR and tDCS to Enhance Cognition in Persons With Mild Cognitive Impairment and Late Life Depression N/A Interventional temporarily suspended due to COVID-19 Anticipated 40
NCT04265235 Terminated EXerCise Intervention in cholesTatic LivEr Disease: The EXCITED Study N/A Interventional COVID pandemic. Recruited 31 out of target 40 patients. Actual 31
NCT04302350 Suspended Application of Nitrous Oxide in Inflation-deflation Process During Thoracoscopic Segmentectomy N/A Interventional because of the COVID-19 pandemic. Anticipated 100
NCT02994914 Terminated GEriatric Determinants of Curative RAdiotherapy Scheme Choice for Breast Cancer ELderly Patient Treatment Compliance and Tolerance N/A Interventional Low rythm of inclusions Actual 241
NCT02999152 Terminated Validation of Radio-induced Damage Biomarkers N/A Interventional Low rythm of inclusions, financial support terminated Actual 16
NCT03643679 Terminated Tobacco Cessation for Sexual Minorities N/A Interventional Covid-19 quarantines and closures prevented recruitment and assessment of participants. Actual 32
NCT03743961 Terminated Geriatric Intervention Contribution on Quality of Life of Elderly Patients With Metastatic Neoplasia Observational Low rythm of inclusions Actual 28
NCT04083469 Terminated Identifying Student Opinion Leaders to Lead E-cigarette Interventions N/A Interventional Covid-19 resulted in school closures. Actual 686
NCT04187378 Suspended Effect of Active Warming on Surgical Site Infections N/A Interventional Due to the COVID-19 pandemic, elective surgeries were temporarily delayed in our country. It's targeted to take cases again as of August 2020. Anticipated 48
NCT04236453 Terminated A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat When Administered as a Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared to the Co-administration of the Separate Agents Phase 1 Interventional COVID-19 pandemic impacted the BE assessment of the trial. The clinical team decided to terminate the trial in order to start a new pivotal BE trial Actual 16
NCT04322227 Terminated Study Investigating Effects of Foliglurax in Patients With Parkinson's Disease (PD) and Healthy Subjects Phase 1 Interventional Study termination due to efficacy results of another study Actual 6
NCT03588741 Terminated Evaluation of Safety Following Immune Tolerance Induction Treatment With Turoctocog Alfa in Patients With Haemophilia A Following Inhibitor Development in NN7170-4213 Trial Phase 3 Interventional The trial was terminated as the participant withdrew from the trial. Actual 1
NCT02700191 Terminated Cardiovascular Diagnosis Using µ-Cor - an Interventional Pilot Trial N/A Interventional Lack of interest Actual 8
NCT03390335 Suspended Decompression Tables for Diving at Altitude N/A Interventional COVID-19 research suspension Anticipated 72
NCT03628976 Suspended Noninvasive VNS for Neuromotor Adaptations N/A Interventional COVID-19 pandemic Anticipated 24
NCT03921359 Terminated SMARTfit Training for Parkinson's Disease N/A Interventional In compliance with research restrictions imposed due to the COVID-19 pandemic. Actual 9
NCT03931928 Suspended Genotype and Phenotype Guided Supplementation of TAMoxifen Standard Therapy With ENDOXifen in Breast Cancer Patients Phase 2 Interventional COVID-19 pandemic Anticipated 750
NCT03953209 Withdrawn Spironolactone for the Treatment of Melasma Phase 1 Interventional Conflict with funding Actual 0
NCT04174326 Suspended CBT Program for Pain Management for Children and Youth With CP (CBT=Cognitive Behavioral Therapy; CP= Cerebral Palsy) N/A Interventional COVID-19 restrictions Anticipated 16
NCT04207138 Withdrawn To Study the Association Among Labor Pain and Physical Parameters in Laboring Pregnant Women Observational change sponsor Actual 0
NCT04271839 Withdrawn Efficiency Control of Fluticasone/Formoterol K-haler (Medium Strength) vs ICS/LABA (High Strength) in Asthma Patients Phase 4 Interventional The trial has been terminated early due to the SARS-CoV-2 pandemic. Actual 0
NCT02530008 Suspended Breast Cancer 2-PREVENT Translational Center of Excellence (TCE) - Metastatic Markers of Recurrent Tumor Phenotype for Breast Cancer Observational Study is suspended due to Abramson Cancer Center suspension of Observational research studies due to the COVID-19 Pandemic. Anticipated 600
NCT03161158 Terminated PURE-HF: Peripheral Ultrafiltration for the RElief From Congestion in Heart Failure N/A Interventional Low recruitment Actual 48
NCT03492710 Withdrawn Study of Immune Globulin Intravenous (Human) GC5101F in Subjects With Primary Humoral Immunodeficiency Phase 3 Interventional A change in sponsor's developmental strategy Actual 0
NCT03778528 Terminated Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome Observational researcher left the institution study will not continue Actual 1
NCT03890380 Terminated Safety and Performance Evaluation of the Magneto Wire N/A Interventional Sponsor's decision Actual 4
NCT03925155 Withdrawn RCT Investigating Pre-cesarean Vaginal Wash of Chlorhexidine vs Povidone-iodine for Patient With Ruptured Amniotic Membrane. Phase 3 Interventional The study was withdrawn from the IRB Actual 0
NCT04073160 Withdrawn TRIO Bladder: A Study of Durvalumab Plus Tremelimumab Followed by Concurrent Durvalumab Plus Bladder Radiation in Muscle-Invasive Bladder Cancer Phase 1 Interventional Study will not be completed. No participants were enrolled. Actual 0
NCT04455919 Terminated Yoga for Chronic Chikungunya N/A Interventional covid health crisis Actual 42
NCT02670083 Terminated A Study Evaluating the Efficacy and Safety of Crenezumab Versus Placebo in Participants With Prodromal to Mild Alzheimer's Disease (AD). Phase 3 Interventional This study was discontinued due to an interim analysis in this study, which indicated that Crenezumab was unlikely to meet its primary endpoint. Actual 813
NCT03114657 Terminated A Study of Crenezumab Versus Placebo to Evaluate the Efficacy and Safety in Participants With Prodromal to Mild Alzheimer's Disease (AD) Phase 3 Interventional This study was discontinued due to an interim analysis in the BN29552 study, which indicated that Crenezumab was unlikely to meet its primary endpoint. Actual 806
NCT00915681 Terminated Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning Phase 2 Interventional Sponsor decision Actual 104
NCT02196051 Withdrawn Basic Research Study to Examine the Relation Between Muscle Insulin Resistance and Lipid Production in the Liver. N/A Interventional Study halted permanently participants are not being enrolled Actual 0
NCT02652702 Terminated Study Comparing Circular Stapler-assisted Colostomy vs Hand-stitching Colostomy of Colorectal Cancer Patients Phase 2 Interventional Not enough patients recruited Anticipated 60
NCT02742844 Terminated Clinical Trial to Investigate Efficacy and Safety of the IMP in Patients With Non Healing Wounds Originating From Ulcers Phase 1/Phase 2 Interventional COVID-19 pandemic and patient recruitment issues Actual 13
NCT03169114 Terminated Raja Isteri Pengiran Anak Saleha Appendicitis Treatment Without Operation N/A Interventional Poor recruitment and terminated during COVID-19 pandemic Actual 81
NCT04361461 Withdrawn Use of Hydroxychloroquine Alone or Associated for Inpatients With SARS-CoV2 Virus (COVID-19) Phase 3 Interventional This study was canceled before enrollment due to a decision by the Sponsor Actual 0
NCT02600429 Terminated Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic Keratopathy : SEER-1 Phase 3 Interventional Business decision Actual 18
NCT03017105 Terminated Cross-education for Proximal Humerus Fracture Rehabilitation Phase 1/Phase 2 Interventional Logistical difficulties leading to an extremely slow recruitment rate Anticipated 40
NCT03023813 Suspended Individualizing Disease Prevention for Middle-Aged Adults N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 130
NCT03076710 Withdrawn Post-Operative Pain Management Following Spine Surgery Observational No participants were identified per inclusion/exclusion criteria Actual 0
NCT04457427 Withdrawn Randomized Study to Investigate the Safety and Performance of Diaphragm Stimulation Coupled With Mechanical Ventilation N/A Interventional Study not started Actual 0
NCT03376399 Withdrawn Potential Benefits of Sleeve Gastrectomy Surgery on Diabetic Gastroparesis Symptoms Observational No participants enrolled. Study terminated at PI's discretion Actual 0
NCT03598907 Terminated Point-of-care Management of Coagulopathy in Lung Transplantation Observational After interim statistical analysis, a statistician reccommended to stop study, because results are significant and in favour of POC approach. Actual 67
NCT03684187 Suspended Mindfulness - Based Intervention in the Treatment of Fatigue in Patients With Primary Biliary Cholangitis N/A Interventional Covid - 19, will resume when able. Anticipated 20
NCT03707457 Terminated Biomarker-Driven Therapy Using Immune Activators With Nivolumab in Patients With First Recurrence of Glioblastoma Phase 1 Interventional Funding/material support withdrawn Actual 3
NCT03890198 Terminated A Phase 1 Study of LCAR-C182A Cells in the Treatment of Advanced Gastric Cancer and Pancreatic Ductal Adenocarcinoma Early Phase 1 Interventional the Preliminary data, progress of this study and the adjustment of the pipeline and strategy . Actual 2
NCT03902275 Terminated Validation of a Quantra Supported Hemotherapy Algorithm in Cardiac Surgery N/A Interventional SARS-CoV-2 Pandemic Actual 20
NCT04051996 Suspended GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia Phase 2 Interventional Temporary Recruitment Hold due to COVID-19 Anticipated 46
NCT04125030 Suspended Convergent and Concurrent Validity Between Clinical Recovery and Personal-civic Recovery in Mental Health Observational [Patient Registry] COVID-19 pandemic Anticipated 200
NCT04132700 Withdrawn Longitudinal Evaluation of Energy Expenditure in ICU Patients From Admission to Discharge Using A Novel Indirect Calorimeter: LEEP-Forward Trial N/A Interventional LEEP-COVID study (NCT04350073) initiation enables inclusion of COVID-positive subjects Actual 0
NCT04395118 Withdrawn STOP HCC: Mailed HCV Treatment Outreach Program for HCC Prevention for Elevated LFTs N/A Interventional Study will not be conducted as a RCT due to limited project timeline. Actual 0
NCT02624700 Terminated 2nd Line Treatment With Pemetrexed and Sorafenib for Recurrent or Metastatic Triple Negative Breast Cancer Phase 2 Interventional Actual 13
NCT03923348 Terminated Pelvic Floor Muscle Training With Leva System for Urge Incontinence N/A Interventional Slow Recruitment and Re-prioritizing of Sponsor-funding Actual 5
NCT03339921 Terminated Botulinum for Chronic Exertional Compartment Syndrome Phase 2/Phase 3 Interventional This study is being closed because it is unworkable. Actual 3
NCT01089374 Suspended Phyllodes Tumor Partial Breast Radiation Study N/A Interventional continuing review Anticipated 50
NCT02387125 Terminated Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1 Phase 1 Interventional This study did not meet the efficacy objective Actual 79
NCT02485990 Terminated Study of Tremelimumab Alone or Combined With Olaparib for Patients With Persistent EOC (Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma) Phase 1/Phase 2 Interventional Withdrawal of sponsor support Actual 24
NCT02826967 Terminated Feasibility and Effectiveness of Colonic Irrigation N/A Interventional COVID-19 institutional restrictions on screening colonoscopies Actual 36
NCT02847130 Suspended Identifying, Understanding, and Overcoming Barriers to the Use of Clinical Practice Guidelines in Pediatric Oncology Observational Reviewing enrolled patients Anticipated 694
NCT03471559 Terminated Cannabidiol - an in Vivo Innovative Drug Delivery Study Phase 1 Interventional Two step study, step two was not feasible based on results from phase one. Actual 8
NCT04078438 Terminated Neurofeedback In Treatment Resistant Depression N/A Interventional Because of researcher foreign training Actual 70
NCT04146012 Suspended BEACH Trial: Bovine Early Access, Compatibility and Hemostasis Trial Phase 3 Interventional Company was sold and clinical trial was suspended Anticipated 75
NCT03791008 Suspended Assessment of Feasibility and Acceptability of Personalized Breast Cancer Screening N/A Interventional Recrutiment was suspended on March 12, 2020 due to the coronavirus pandemic Anticipated 385
NCT04323631 Withdrawn Hydroxychloroquine for the Treatment of Patients With Mild to Moderate COVID-19 to Prevent Progression to Severe Infection or Death Early Phase 1 Interventional Trial not started due to accumulating evidence against HCQ for COVID Actual 0
NCT04164082 Suspended Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer Phase 2 Interventional Other - Planned safety stopping Anticipated 163
NCT03846492 Suspended Targeting Brain Physiology to Treat Neuropsychiatric Symptoms of Dementia Using TMS-EEG and tDCS N/A Interventional Suspended due to COVID-19 Anticipated 90
NCT00003060 Terminated Chemotherapy Plus Bone Marrow Transplantation in Treating Patients With Metastatic Melanoma Phase 1 Interventional lack of patient accrual Anticipated 6
NCT03396484 Withdrawn Methyldopa for Reduction of DQ8 Antigen Presentation in At-Risk Subjects for Type 1 Diabetes Phase 2 Interventional Study not begun due to continued laboratory work on the feasibility of outcome measures. Actual 0
NCT03944707 Terminated Study of Efficacy and Safety of LOU064 in Inadequately Controlled Asthma Patients Phase 2 Interventional Company decision Actual 76
NCT04020549 Withdrawn Single-Session Computerized Mental Health Intervention for Rural Indian Adolescents N/A Interventional In collaboration with community partners, we determined that the reading level required for the intervention did not make it suitable for the adolescents. Actual 0
NCT04160091 Terminated Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Adhesive Capsulitis Phase 2 Interventional The study was terminated prematurely due to the COVID-19 pandemic creating uncertainty impacting trial progress and costs. Actual 19
NCT04290637 Suspended The Galway Sea Swimmers Study N/A Interventional Unable to recruit during COVID-19 crisis Anticipated 150
NCT04330300 Suspended Coronavirus (COVID-19) ACEi/ARB Investigation Phase 4 Interventional Challenges with funding and very low incidence of COVID-19 at Irish study site Anticipated 2414
NCT02609984 Terminated Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002) Phase 2 Interventional This study did not meet the efficacy objective Actual 89
NCT01510691 Withdrawn Vitrectomy Retinal Oxygenation Observational Difficulties in recruiting participants Actual 0
NCT02477124 Suspended A See and Treat Paradigm for Cervical Pre-cancer N/A Interventional COVID-19 Anticipated 200
NCT02673021 Terminated MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s) N/A Interventional Funding suspended prior to completing enrollment of all participants. Actual 6
NCT03323645 Terminated Prosthetics Registry and Outcomes in Urology at Duke Observational change of study structure and resource allocation Actual 190
NCT03339973 Terminated Allogeneic ABCB5-positive Stem Cells for Treatment of PAOD Phase 1/Phase 2 Interventional Very slow recruitment of patients and the current COVID-19 pandemic situation. Actual 24
NCT03457818 Terminated Therapy of the Skeletal Disease of Type 2 Diabetes With Denosumab Phase 2 Interventional Due to enrollment difficulties compounded by the COVID pandemic. Actual 8
NCT04409483 Withdrawn Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger Phase 3 Interventional Epidemic dynamics Actual 0
NCT02753595 Terminated Study of Eribulin Mesylate in Combination With PEGylated Recombinant Human Hyaluronidase (PEGPH20) Versus Eribulin Mesylate Alone in Subjects With Human Epidermal Growth Factor Receptor 2 (HER2)-Negative, High-Hyaluronan (HA) Metastatic Breast Cancer (MBC) Phase 1/Phase 2 Interventional evolving standard of care and difficulties of enrolling participants Actual 25
NCT03491150 Terminated An Open-Label Crenezumab Study in Participants With Alzheimer's Disease Phase 3 Interventional This study was discontinued due to an interim analysis in the BN29552 study, which indicated that Crenezumab was unlikely to meet its primary endpoint. Actual 149
NCT04451382 Terminated PTNS vs Botox of Refractory OAB Observational Low recruitment Actual 150
NCT03143985 Suspended Vactosertib in Combination w/ Pomalidomide in Relapsed or Relapsed and Refractory Multiple Myeloma Phase 1 Interventional Major revisions due Anticipated 18
NCT02985554 Terminated Phase I Study to Assess the Tolerability and Efficacy of Nivolumab in Patients With Hematologic Malignancies Phase 1 Interventional Study stopped early due to slow accrual and safety concerns. Actual 3
NCT01301482 Terminated Ear Acupuncture for Acute Sore Throat in Patients Unable to Take Non-steroidal Anti-inflammatory Agents (NSAIDs) N/A Interventional Study is no longer necessary (outmoded, outdated, science has changed) Actual 2
NCT03020264 Terminated Frequency of Hypoglycemia in Patients With Type 2 Diabetes Under Insulin Therapy Older Than 75 Years in Real Life N/A Interventional COVID-19 Actual 161
NCT03475043 Suspended Neuroplasticity in Auditory Aging_Project 2 N/A Interventional coronavirus pandemic, no human subjects research at UMD Anticipated 405
NCT03868436 Suspended PENTHROX™ in the Canadian Emergency Department (ED) Phase 4 Interventional Recruitment is complete however study suspended due to COVID 19 Actual 99
NCT03910322 Terminated The Effect of a Probiotic Strain on Aspirin-induced GI Damage N/A Interventional Decision made by Sponsor Actual 30
NCT04231682 Withdrawn A Study to Evaluate Efficacy and Safety of Denosumab for Prevention and Treatment of Osteoporosis in 1st Time Liver Transplant Recipients. Phase 2 Interventional Grant support was withdrawn from Amgen Pharmaceuticals Actual 0
NCT04259190 Withdrawn A Comparison of Treatment Rationales on Willingness to Tolerate Distress in Interoceptive Exposure N/A Interventional Halted due to COVID-19. Actual 0
NCT04329403 Withdrawn Clinical Endpoint Bioequivalence Study of Adapalene Gel 0.1% Phase 3 Interventional Market reasons Actual 0
NCT03051698 Terminated C1-inhibitor in Allergic ASThma Patients Phase 4 Interventional Interim analysis showed no differences between groups Actual 37
NCT00839787 Withdrawn The Effect of Pain Medication in Children With Acute Abdominal Pain and Its Implication Over the Surgeon's Decision N/A Interventional Unable to enroll more patients Actual 0
NCT01785069 Terminated Safety and Effectiveness of NATRELLE® 410 Highly Cohesive, Anatomically Shaped, Silicone-filled X-Style and L-Style Breast Implants N/A Interventional There was no indication that long-term follow-up would differ between any of the studies that have evaluated devices within the 410 Style Matrix. Actual 355
NCT03255213 Suspended Lingual Muscle Training in Late-Onset Pompe Disease (LOPD) N/A Interventional Due to COVID19 restrictions Anticipated 5
NCT03488147 Suspended Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery Phase 2 Interventional Change in Investigational Drug Service policies resulting in the need to change the operational design of the overall protocol. Anticipated 500
NCT03567291 Terminated Evaluation of Safety and Tolerability of Long-term TEV-50717 (Deutetrabenazine) for Treatment of Tourette Syndrome in Children and Adolescents Phase 3 Interventional The parent trials did not meet the primary endpoints of reduction in motor and phonic tics. Actual 228
NCT03836885 Withdrawn Apremilast - Oral Lichen Planus Trial Phase 2 Interventional Study was terminated due to delay in enrollment. Actual 0
NCT03890861 Suspended Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)" N/A Interventional Temporarily paused due to COVID-19 and expected to resume. Anticipated 200
NCT04020926 Terminated Impact of Hyponatremia on Muscle Strength, Gait and Cognitive Function Observational Study was stopped due to COVID-19 pandemic. Actual 8
NCT04162145 Terminated BRIDGE Device for Treatment of Opioid Withdrawal N/A Interventional Due to COVID-19 pandemic Actual 12
NCT04177459 Terminated Rehabilitation of Adolescents Living With Chronic Fatigue N/A Interventional Covid-19 Actual 3
NCT04285008 Withdrawn Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation N/A Interventional Sponsor has terminated study due to COVID-19 related concerns Actual 0
NCT04354441 Withdrawn Effect of Hydroxychloroquine in COVID-19 Positive Pregnant Women Phase 2 Interventional Not started Actual 0
NCT03128931 Terminated SedLine Engineering Data Collection Study in Pediatric Patients Undergoing General Anesthesia or Sedation N/A Interventional Study was terminated as enrollment rate did not meet the requirement of the Sponsor. Actual 45
NCT03728673 Suspended A Study Utilizing Escitalopram in Glioma Patients Phase 2 Interventional COVID-19 safety precautions Anticipated 20
NCT04449445 Suspended Perioperative Nutritional Optimization in Head and Neck Cancer Patients N/A Interventional COVID-19 Anticipated 300
NCT02351869 Terminated Nitrous Oxide as a Putative Novel Dual-Mechanism Treatment for Bipolar Disorder Phase 2 Interventional This study was terminated due to COVID-19 pandemic-related halting of recruitment in the context of an upcoming replacement of the study MRI scanner. Actual 25
NCT02362191 Terminated Targeting Inter-Hemispheric Alpha Coherence With tACS To Treat PMDD N/A Interventional The study was terminated because the dense treatment schedule precluded successful recruitment of study participants. Actual 13
NCT03082612 Suspended Overcoming Psychological Distress Through Hymns N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Actual 12
NCT03135262 Terminated A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax in Participants With R/R Diffuse Large B-Cell Lymphoma (DLBCL) Phase 1/Phase 2 Interventional Sponsor's decision to terminate the study after Phase 1; will not proceed with Phase 2. Actual 29
NCT03375606 Terminated Assessing the Safety and Tolerability of CSL730 in Healthy Caucasian and Japanese Adults Phase 1 Interventional The Sponsor decided to terminate this study in favor of development of subcutaneous administration. Actual 26
NCT03540043 Terminated Thykamine Safety and Efficacy Study in Mild-to-Moderate Atopic Dermatitis Phase 2 Interventional Reached required analyzable sample size; COVID-19 recruitment challenges Actual 162
NCT04202718 Withdrawn VitalConnect VitalPatch ECG Interpretation/Arrhythmia Detection N/A Interventional Study never started due to COVID-19 pandemic Actual 0
NCT01832727 Terminated Phase 1b/2, Multicenter, Open-label Study of Oprozomib and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma Phase 1/Phase 2 Interventional Enrollment halted during phase 2 to reformulate the investigational product Actual 65
NCT02996448 Terminated Safety, Tolerability, and Immunogenicity of One Dose of NDV 3A Vaccine in People With STAT3-Mutated Hyper-IgE Syndrome Phase 2 Interventional Safety concerns led to early termination. Actual 3
NCT03982537 Withdrawn Effect of N-Acetyl Cysteine (NAC) on the Oral Microbiome Phase 2 Interventional Concept is withdrawn and a different concept will be submitted the near future. Actual 0
NCT04190069 Withdrawn Effects of Behavioral Interventions on Weight Loss and Weight Maintenance N/A Interventional IRB recommended change to registry study or quality improvement project status Actual 0
NCT00263562 Terminated Steroid Treatment for Sickle Cell Pain Crisis Phase 3 Interventional poor enrollment, availability of more effective medications Actual 18
NCT02395627 Terminated Reversing Therapy Resistance With Epigenetic-Immune Modification Phase 2 Interventional Insufficient efficacy in an unselected patient population Actual 38
NCT02352155 Terminated Second-look Endoscopy in High Risk Patients After Endoscopic Hemostasis to Their Bleeding Peptic Ulcers Improves Their Outcomes N/A Interventional Actual 157
NCT02899481 Terminated Role of Intrapartum Ultrasound in Instrumental Delivery N/A Interventional Data Safety Monitoring Committee recommended stopping the trial due to futility. Actual 222
NCT02953119 Terminated Prehabilitation for Elective Major Abdominal Surgery N/A Interventional Difficulty recruiting patients Actual 20
NCT03064152 Terminated Rotational Thromboelastometry for the Transfusion Management of Postpartum Hemorrhage After Vaginal or Cesarean Delivery N/A Interventional slow enrollment, outcome measures collected but actual enrollment is below target enrollment Actual 49
NCT03736421 Suspended Observational Study to Evaluate Peripheral IntraVenous Analysis (PIVA) in Euvolemic, Hypovolemic, and Hypervolemic Emergency Department Patients Observational Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 280
NCT04140591 Terminated Proton Pump Inhibitor Plus Propranolol Versus Proton Pump Inhibitor Alone on Peptic Ulcer Healing in Patients With Liver Cirrhosis Phase 2/Phase 3 Interventional 1. Most patients with liver cirrhosis already use PPI and NSBB 2. 90 % Peptic ulcer size is smaller than 5cm Actual 10
NCT04251182 Suspended Clinical Study Evaluating Efficacy and Safety of T3D-959 in Mild-to-moderate AD Subjects Phase 2 Interventional COVID-19 Panemic Anticipated 256
NCT03136900 Terminated Impact on the Nitrogen Balance, Autonomy, Safety and Tolerance of Enteral Diets Made of With Nutrilon Without Lactose® Fortified by Concentration Versus by Maltodextrin and Oil Supplementation,After Surgery for Congenital Heart Disease, in Infants. N/A Interventional Recuitment to slow Actual 41
NCT02708849 Terminated The Sustained Effects of Ketamine Phase 1 Interventional Actual 3
NCT01803984 Terminated MIBRAIN - Migraine and the Brain: Consequences, Causes, and Vascular Interaction Observational Actual 166
NCT02501473 Terminated Study of Intratumoral G100 With Or Without Pembrolizumab or Rituximab In Patients With Follicular Non-Hodgkin's Lymphoma (MK-3475-174/IMDZ-G142) Phase 1/Phase 2 Interventional Business reasons Actual 52
NCT02702518 Terminated rhDNase Eye Drops in Patients With Ocular Graft-Vs.-Host Disease Phase 1/Phase 2 Interventional The DSMB committee recommended closing the trial because of the COVID-19 risk in this "at-risk" oGVHD population if they came for study visits. Actual 58
NCT03532009 Terminated Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure Phase 2 Interventional Study stopped early due to the COVID-19 pandemic Actual 182
NCT03732196 Terminated Food Frequency Questionnaire for Chinese Pregnant Women Observational Unable to recruit enough participants Actual 68
NCT03925493 Suspended Exercise Prescription in Cardiac Rehabilitation N/A Interventional The COVID-19 pandemic has caused us to suspend recruitment. Anticipated 60
NCT04225078 Suspended A Study to Evaluate the Effects of Loperamide (JNJ-289679) on Electrocardiogram Intervals in Healthy Adult Participants Phase 1 Interventional Trial was put On Hold due to COVID-19. The Site will not start recruiting activities until further notice Anticipated 52
NCT04232878 Terminated A Single Ascending Dose Trial of CVL-936 in Healthy Subjects Phase 1 Interventional Sufficient data has been obtained to meet current objectives Actual 10
NCT04346355 Terminated Efficacy of Early Administration of Tocilizumab in COVID-19 Patients Phase 2 Interventional Based on interim analysis for futility and given an enrolment rate almost nil Actual 126
NCT04363203 Suspended VA Remote and Equitable Access to COVID-19 Healthcare Delivery (VA-REACH TRIAL) Phase 3 Interventional concerns related to study drug Anticipated 300
NCT04416178 Suspended Sickle Cell Disease and the Genomic Needs of Parent and Pediatric Stakeholders Observational Temporary Enrollment Hold due to COVID-19 Anticipated 300
NCT04390386 Withdrawn Controlled Study of IC14 for Treatment of ALS Phase 2 Interventional contract not yet signed Actual 0
NCT01697293 Terminated Triciribine Phosphate, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patients With Stage IIB-IV Breast Cancer Phase 1/Phase 2 Interventional criteria for continuing enrollment in Phase 2 portion was not met Actual 34
NCT02069431 Terminated Oxytocin Aging Study Phase 1 Interventional This study was halted prematurely due to the COVID-19 pandemic, resulting in the inability to enroll participants. Funding for this project has also ended. Actual 153
NCT02070666 Terminated Preventive Strategies in Acute Respiratory Distress Syndrome (ARDS) N/A Interventional Low recruitment and published data with no benefit Actual 98
NCT03051282 Suspended Genetic Determinants of ACEI Prodrug Activation Phase 4 Interventional Enrollment and interactions/interventions are paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 36
NCT03326804 Suspended H1 Hip Resurfacing Arthroplasty Observational awaiting data points for data analysis Anticipated 250
NCT03894579 Withdrawn Autologous Natural Killer Cells in Subjects With Plaque Psoriasis Phase 1 Interventional Study withdrawn per NKMax America Actual 0
NCT03978936 Suspended Medication Adherence With Telehealthcare Medication Therapy Management Phase 3 Interventional Study recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 300
NCT03998514 Suspended A Phase 1a/1b Study of CB4211 in Healthy Non-obese Subjects and Subjects With Nonalcoholic Fatty Liver Disease Phase 1 Interventional COVID-19 related delay Anticipated 86
NCT04240158 Terminated IW-6463 Safety Study in Healthy Elderly Subjects Phase 1 Interventional Some subjects could not complete the second crossover period due to COVID-19-related site closure. The study was closed to allow analysis of all collected data. Actual 24
NCT04362332 Terminated Chloroquine, Hydroxychloroquine or Only Supportive Care in Patients AdmItted With Moderate to Severe COVID-19 Phase 4 Interventional Currently, almost no patients admitted to Dutch hospitals. If any effect of HCQ is to be expected we need more than 1000 inclusions Actual 25
NCT04369742 Suspended Treating COVID-19 With Hydroxychloroquine (TEACH) Phase 2 Interventional Investigator decision Anticipated 626
NCT03790683 Suspended Intraoperative Warming During Major Surgical Procedures Using the Esophageal Temperature Management System N/A Interventional Sponsor funding limitations Anticipated 48
NCT03234153 Terminated Neoadjuvant Immunotherapy With Durvalumab and Tremelimumab for Bladder Cancer Patients Ineligible for Cisplatin Phase 2 Interventional low accrual Actual 6
NCT04361552 Withdrawn Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection) Phase 3 Interventional Study abandoned due to drug billing issues Actual 0
NCT03502954 Terminated A Study to Investigate the Safety, Tolerability and Pharmacokinetics of ABY-039 Phase 1 Interventional Halted prematurely Actual 66
NCT02220790 Suspended BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia Observational [Patient Registry] Final enrollment on hold due to COVID-19 restrictions Anticipated 515
NCT02419105 Terminated Effects of Transdermal Testosterone and/or Monthly Vitamin D on Fall Risk in Pre--frail Hypogonadal Seniors Phase 3 Interventional Delayed recruitment mainly due to a screening to inclusion rate much lower than expected. Due to the delayed recruitment IMP reached the end of its shelf life. Actual 91
NCT02565511 Terminated A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease Phase 2/Phase 3 Interventional Study was terminated by Novartis after a planned review by DMC of unblinded data identified worsening in some measures of cognitive function Actual 480
NCT02733614 Suspended Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD Phase 2 Interventional COVID-19 Anticipated 52
NCT02868827 Terminated Cholecalciferol Supplementation in Critically Ill Patients With Severe Vitamin D Deficiency. Phase 2/Phase 3 Interventional The initial plan was 2 years but due to slow recruitment. We were able to screen 635 patients in 4 years and recruited only 127 patients. Actual 127
NCT03132428 Terminated Registry to Evaluate INOmax in Newborn Babies With Pulmonary Hypertension Observational Positive results at interim analysis Actual 140
NCT03246919 Terminated Ideal Time of Oxytocin Infusion During Cesarean Section Phase 4 Interventional PI left Loyola and Sub-I graduated. Actual 68
NCT03472924 Terminated The Effects of Kinesio Tape® on Arthrogenic Muscle Inhibition and Rate of Torque Development N/A Interventional Insufficient recruitment and enrollment. Reduction in study personnel capacity. Actual 6
NCT03475602 Terminated Membranous Nephropathy-associated Serological Antibody Predict the Prognosis of Idiopathic Membranous Nephropathy Observational [Patient Registry] Our center had adopted a new detection method for anti-PLA2R antibodies in all membranous nephropathy patients. Actual 85
NCT03543033 Withdrawn Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes N/A Interventional The study was closed by the investigators due to lack of study population to enroll. Actual 0
NCT03598036 Terminated Dose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental Glomerulosclerosis Phase 2 Interventional Low recruitment rate Actual 5
NCT03718338 Suspended Mechanisms of Metabolic and Hormone Action on Plaque Formation in Brain and Carotid Vessels in Prostate Adenocarcinoma Observational COVID19 Suspension Anticipated 30
NCT03850509 Terminated Efficacy and Safety of Oral OPS-2071 in Subjects With Crohn's Disease Showing Symptoms of Active Inflammation Phase 2 Interventional Sponsor Decision Actual 3
NCT02193282 Suspended Erlotinib Hydrochloride in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Completely Removed by Surgery (An ALCHEMIST Treatment Trial) Phase 3 Interventional Other - Modifications to MCF Anticipated 450
NCT04175132 Terminated Binding of Foliglurax to Regions in the Brain in Healthy Participants and in Patients With Parkinson's Disease (PD) Phase 1 Interventional New efficacy data from another study Actual 6
NCT04242966 Withdrawn The Effect of Higher Protein Dosing in Critically Ill Patients Ultrasound a Sub-study Phase 3 Interventional Study never started. Operational issues prevented study from rolling out Actual 0
NCT04282798 Withdrawn Racial Variation in Response to Music Interventions for People With Alzheimer's Dementia N/A Interventional COVID delay and subsequent unavailability of staff. Actual 0
NCT03127124 Suspended QUILT-2.022 NANT-008 in Combination w/ 5-fluorouracil, Bevacizumab, Leucovorin & Oxaliplatin in Subjects With Pancreatic Cancer Phase 1/Phase 2 Interventional IRB Recommendation Anticipated 64
NCT03418649 Suspended Eplerenone as a Supplement to Epidural Steroid Injections Phase 4 Interventional Unable to recruit during COVID-19 epidemic restrictions on associated clinical practice Anticipated 40
NCT04436770 Suspended Medical Recovery and Social Reintegration for Post-stroke Patients Using Virtual Reality N/A Interventional Due to the COVID-19 pandemic Actual 52
NCT03906448 Terminated FORWARD Optune and Adjuvant TMZ in Grade II/III Astrocytoma Phase 2 Interventional The study was terminated because the Study Chair/IDE Sponsor and Novocure determined that conducting this trial was not feasible without CMS approval. Actual 2
NCT03957278 Suspended A Study to Evaluate the DAISe System During Neurointervention for Acute Ischemic Stroke N/A Interventional Device modifications Anticipated 120
NCT03987750 Withdrawn Safinamide for Levodopa-induced Dyskinesia (PD-LID) Phase 3 Interventional drug development plan has been updated Actual 0
NCT04329611 Suspended ALBERTA HOPE COVID-19 for the Prevention of Severe COVID19 Disease Phase 3 Interventional Enrolment was suspended on 22may2020, after Mehra et al (Lancet 2020) suggested excess toxicity of HCQ. Anticipated 1660
NCT03707600 Withdrawn State and Trait Mediated Response to TMS in Substance Use Disorder N/A Interventional PI closing his lab Actual 0
NCT04434378 Terminated Tamsulosin to Prevent Postoperative Urinary Retention in Laparoscopic Inguinal Hernia Repair Phase 4 Interventional Significant difference not reached on interim analysis Actual 170
NCT02925988 Terminated Combined Amplitude-integrated and Conventional EEG Monitoring in High-risk Critically Ill Neonates N/A Interventional Actual 4
NCT04434872 Terminated Fecal Microbiota Transplantation as a Treatment for Ulcerative Colitis Phase 2 Interventional Lack of budget Actual 80
NCT00855907 Terminated Fatty Liver in Inflammatory Bowel Disease (IBD) Patients Observational Lack of budget Actual 100
NCT03940287 Terminated Muscle Energy Technique and Kinesiotaping in Mechanical Sacroiliac Joint Dysfunction N/A Interventional Due to COVID-19 lockdown Actual 30
NCT03940339 Terminated Suboccipitalis Myofascial Release in Hamstring Tightness in Patients With Anterolisthesis N/A Interventional Due to COVID-19 lockdown Actual 32
NCT03974009 Terminated Calcaneal Taping on Balance, Gait and Range of Motion in Chronic Stroke Survivors N/A Interventional Due to COVID-19 lockdown Actual 18
NCT04129489 Terminated A Phase 2a Study to Evaluate the Safety and Efficacy of Cannabidiol Only as Maintenance Therapy and Steroid Sparing in Patients With Stable Autoimmune Hepatitis Phase 2 Interventional low recruitment Actual 2
NCT04247308 Suspended Multi Modal Stimulations in Pre-term Neonates N/A Interventional Due to COVID-19 lockdown Anticipated 56
NCT02825043 Terminated HFNC Effect on BCSS in Patients With COPD N/A Interventional Slow enrollment and unable to meet enrollment targets Actual 6
NCT02178566 Terminated Pulmonary Rehab in Chronic Obstructive Pulmonary Disease (COPD): Response to Tyvaso Phase 2 Interventional Unable to enroll Actual 4
NCT03269968 Terminated Use of Negative Pressure Wound Therapy in Morbidly Obese Women After Cesarean Delivery N/A Interventional Recruitment difficulty Actual 25
NCT03738228 Suspended Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer Phase 1 Interventional Scheduled Interim Monitoring Anticipated 40
NCT03774784 Terminated A Study of the Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) Disease Observational The study was terminated due to the impacts of COVID-19 on patient safety and enrollment. Actual 26
NCT04044209 Suspended A Study of the IDH1 Inhibitor AG-120 in Combination With the Checkpoint Blockade Inhibitor, Nivolumab, for Patients With IDH1 Mutated Relapsed/Refractory AML and High Risk MDS Phase 2 Interventional COVID-19 temporary suspension Anticipated 45
NCT04285190 Withdrawn The Effect of T89 on Improving Oxygen Saturation and Clinical Symptoms in Patients With COVID-19 N/A Interventional The COVID-19 pandemic in China has ended completely. As a result, patient recruiting is impossible in China. Actual 0
NCT04285268 Withdrawn Rituximab, Venetoclax, and Bortezomib for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma Phase 2 Interventional funding available Actual 0
NCT04287491 Withdrawn Use Of Virtual Reality For Pain Control in Dermatological Bedside Procedures N/A Interventional Lack of funding Actual 0
NCT04333914 Suspended Prospective Study in Patients With Advanced or Metastatic Cancer and SARS-CoV-2 Infection Phase 2 Interventional Potential recrutment related to the epidemic context. Anticipated 384
NCT04432415 Suspended Comparison of Silver Diamine Fluoride and Sodium Fluoride Varnish to Prevent and Arrest Root Caries in Older Adults N/A Interventional Coronavirus Pandemic Actual 90
NCT03026166 Terminated A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer Phase 1/Phase 2 Interventional Enrollment was stopped after the dose-limiting toxicity (DLT) evaluation phase of Cohort 2. Actual 42
NCT02997228 Suspended Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer, the COMMIT Study Phase 3 Interventional Other - Study requires an approved DTL template Anticipated 200
NCT01003769 Terminated Lenalidomide and AT-101 in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia Phase 1/Phase 2 Interventional Lack of funding Actual 5
NCT02119312 Suspended Malaria Clinical Trials Center General Screening Observational [Patient Registry] COVID19 safety measures-institutional policy to suspend non-covid related studies Anticipated 3500
NCT02521870 Terminated A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Phase 1/Phase 2 Interventional A strategic restructuring including the planned conclusion of clinical oncology development programs and no further sponsoring of the development of SD-101. Actual 241
NCT02764086 Terminated INTENSE: A Phase I/II Study of INhomogeneous Targeted Dose Escalation in Non-Small CEll Lung Cancer Phase 1/Phase 2 Interventional Accrual lower than anticipated and not expected to improve Actual 6
NCT03731117 Suspended FURosemide Stress Test to Predict Need of Renal Replacement THERapy in Ischemic Acute Tubular Necrosis in ICU Phase 4 Interventional Study with inclusions suspended due to COVID-19 since 18th march 2020 Anticipated 70
NCT04284462 Terminated Liking Adaptation to Beverages of Varying Sweetness Levels After Prolonged Exposure N/A Interventional Sponsor decision to stop study due to COVID-19 pandemic Actual 170
NCT04431232 Suspended Endo-Band: Endoscopic Band Ligation for Weight Loss N/A Interventional Due to COVID-19 pandemic Anticipated 5
NCT02357004 Withdrawn Mechanisms of Refractory Hypertension (Carvedilol) N/A Interventional Actual 0
NCT02357017 Withdrawn Mechanisms of Refractory Hypertension (High and Low Salt Diet) N/A Interventional Actual 0
NCT03403751 Terminated Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury Phase 3 Interventional Very slow enrollment of target patient population Actual 58
NCT03489512 Withdrawn Comparison Trial for Chloraprep Versus Aqueous Chlorhexidine (2%) for the Prevention of Catheter-related Bacteremia Phase 4 Interventional Administrative issues Actual 0
NCT03053050 Terminated Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis Phase 3 Interventional This study was terminated early due to lack of efficacy based on the results of the Week 48 analysis as prespecified in the clinical study protocol. Actual 808
NCT04106700 Suspended Prophylaxis With Apixaban in Transplant Eligible Patients With Multiple Myeloma Receiving Induction Therapy With IMiDs Phase 2 Interventional Low recruitment Anticipated 60
NCT04428762 Withdrawn Glycemic Control and Quality of Life With i- Port Advance in Pediatric T1DM N/A Interventional we decided to change the protocol completely to an RCT. Actual 0
NCT00230308 Suspended Identification and Characterization of Novel Proteins and Genes in Head and Neck Cancer Observational Suspended due to Covid-19 Anticipated 500
NCT02568917 Suspended Effectiveness of ART and Conventional Treatment - Practice-based Clinical Trial N/A Interventional There was a problem with the municipality and they have choose to suspend it. Anticipated 800
NCT03054636 Terminated Short-term Perfusion Angiography Pilot Study (SPA) Observational After data review of enrolled pts, it was determined that initial study objectives would not be met w/ continuation of enrollment Actual 38
NCT03292536 Terminated Merestinib on Bone Metastases in Subjects With Breast Cancer Phase 1 Interventional Enrollment incomplete by the end of the contracted enrollment period Actual 2
NCT03724253 Terminated [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR) Phase 2 Interventional Recruitment was stopped before the target sample size was achieved. Actual 19
NCT03745196 Terminated The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases Phase 2 Interventional The study is being terminated early as a result of the coronavirus (COVID-19) outbreak. Actual 13
NCT03785730 Suspended Ultraconservative Caries Treatment in Anterior Cavitated Caries Lesion of Primary Teeth N/A Interventional Outbreak of COVID-19. Anticipated 196
NCT03785769 Suspended Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement N/A Interventional The Outbreak of COVID-19. Anticipated 192
NCT03827889 Suspended Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth N/A Interventional Outbreak of COVID-19. Anticipated 168
NCT03870841 Terminated The Effect of PC945 on Aspergillus Fumigatus Lung Infection in Patients With Cystic Fibrosis Phase 2 Interventional The study is being terminated early as a result of the coronavirus (COVID-19) outbreak. Actual 4
NCT03905447 Terminated The Effect of Early Treatment of PC945 on Aspergillus Fumigatus Lung Infection in Lung Transplant Patients. Phase 2 Interventional The study is being terminated early as a result of the coronavirus (COVID-19) outbreak. Actual 2
NCT03908944 Withdrawn Postoperative Pain and Headache After Craniotomy Phase 2 Interventional PI- Dr. Jellish passed away. The study was terminated with the IRB Actual 0
NCT03966300 Suspended Improving the School Vaccination Experience: What CARDs Are You Going to Play? N/A Interventional Study suspended because of Covid-19 - no vaccinations are occurring in schools Anticipated 1400
NCT03966391 Suspended Effectiveness of CARD for Improving School-Based Immunizations N/A Interventional Study suspended because of Covid-19 - there are no vaccinations in schools Anticipated 7800
NCT04344379 Suspended Prevention of SARS-CoV-2 in Hospital Workers s Exposed to the Virus Phase 3 Interventional suspension of clinical trials with hydroxychloroquine by health authorities Actual 122
NCT04393597 Withdrawn Effects of Food on the Pharmacokinetics of DWJ1458 in Healthy Adults Phase 1 Interventional We decided to discontinue this particular clinical study through internal discussion. Actual 0
NCT02212730 Terminated A Study Evaluating the Effect of Pembrolizumab (MK-3475) in Participants With Renal Cell Cancer (MK-3475-031) Phase 1 Interventional Terminated early due to low enrollment Actual 10
NCT02328287 Terminated Study on Allogeneic Osteoblastic Cells Implantation in Rescue Interbody Fusion Phase 2 Interventional Actual 6
NCT02501265 Suspended Adaptive Pharmacotherapy for Smoking Cessation Phase 2 Interventional Enrollment suspended due to COVID-19 Anticipated 188
NCT02665988 Terminated Adjunctive Transcranial Direct Current Stimulation N/A Interventional We terminated the study because the Pain Management Program closed in January 2018. Actual 4
NCT03079102 Terminated Inhaled Nitric Oxide After Out-of-Hospital Cardiac Arrest Phase 2 Interventional Slow enrollment and planned change of institution by PI Actual 57
NCT03186937 Suspended A Window of Opportunity Study of Methionine Deprivation in Triple Negative Breast Cancer Phase 2 Interventional due to COVID-19 Anticipated 25
NCT03277222 Terminated Intranasal Treatment of HIV-associated Neurocognitive Disorders Phase 2 Interventional Unable to find further eligible participants Actual 4
NCT03318757 Withdrawn Bupivacaine Liposomal Injectable Suspension, Pain and Narcotic Use After Elective Orthognathic Surgery Phase 4 Interventional The research could not be conducted as it was denied by the IRB. Actual 0
NCT03819686 Suspended Reducing Disparities in Living Donor Transplant Among African Americans N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 850
NCT03914079 Suspended Evaluation of the CAD-det System, a Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease Observational [Patient Registry] Sponsor due to COVID-19 Anticipated 2000
NCT03988582 Withdrawn Safety and Effectiveness of EBV-specific Cytotoxic T Cells for the Treatment for EBV Lymphomas or Other EBV-associated Malignancies Phase 2 Interventional Lack of accrual Actual 0
NCT03995966 Suspended A Clinical Trial for Self-Injurious Behavior N/A Interventional Paused due to COVID-19 and expected to resume; Not a suspension of IRB approval. Anticipated 30
NCT04149444 Withdrawn A Study of Trifluridine/Tipiracil in Triple Negative Metastatic Breast Cancer Phase 2 Interventional Sponsor withdrew support Actual 0
NCT04257214 Suspended Therapy and Peer Support for Patients Taking Medication for Opioid Use Disorder N/A Interventional COVID-19 Anticipated 440
NCT04428242 Withdrawn Study Evaluating Retinal Health Monitoring System Thickness Module Observational COVD-19 Actual 0
NCT01926301 Withdrawn Cerebrovascular Autoregulation in Sepsis, Influence of Renal Replacement Therapy Observational Actual 0
NCT01978509 Terminated The Affect of Low-Volume Bowel Preparation for Hospitalized Patients Colonoscopies N/A Interventional Lack of enrollment Actual 32
NCT02173470 Terminated Chest CT With Iterative Reconstruction as an Alternative to Conventional Chest X-ray Prior to Heart Surgery N/A Interventional Expected futility in reaching the primary endpoint Actual 866
NCT02317302 Terminated FDG Tumor Heterogeneity During Chemoradiation as a Predictor of Response in Patients With Cervical Cancer Phase 1 Interventional Insufficient funding Actual 48
NCT02462200 Terminated Shave Margins in Breast Conservation Therapy Phase 2 Interventional Insufficient funding Actual 81
NCT02542241 Terminated Hypertonic Saline Resuscitation in Trauma Patients After Hemorrhage Control Phase 4 Interventional lack of funds to continue recruitment Actual 52
NCT02887248 Terminated Nab-paclitaxel Plus Gemcitabine as First-line Therapy for Cisplatin-ineligible or Cisplatin-incurable Advanced Urothelial Carcinoma Phase 2 Interventional Enrollment issues Actual 3
NCT03138083 Terminated OMO-1 in Solid Malignancies Phase 1/Phase 2 Interventional strategic reasons (not due to lack of efficacy or safety issues) Actual 40
NCT03300609 Terminated 5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab Phase 3 Interventional Insufficient Accrual Actual 4
NCT03726905 Suspended Complex Exercises of the Respiratory Muscles Plus Aerobic Training vs. Aerobic Training in Patients With СHF N/A Interventional Study suspended because of COVID 19 Anticipated 60
NCT03856580 Suspended Long-acting Biomedical HIV Prevention in Transgender Women N/A Interventional Due to COVID-19 pandemic Anticipated 45
NCT03864328 Terminated A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF Phase 2 Interventional COVID-19 Pandemic Actual 108
NCT03929068 Suspended Sinemet for Spasticity and Function in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis Phase 1 Interventional COVID-19 Pandemic Anticipated 15
NCT04090879 Suspended Low Nicotine Content Cigarettes in Vulnerable Populations: Affective Disorders Phase 2 Interventional COVID19 pandemic Anticipated 232
NCT04092101 Suspended Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder Phase 2 Interventional COVID19 pandemic Anticipated 310
NCT04092387 Suspended Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age Phase 2 Interventional COVID19 pandemic Anticipated 246
NCT04345861 Terminated Hydroxychloroquine Plus Azithromycin Versus Hydroxychloroquine for COVID-19 Pneumonia (COVIDOC Trial) Phase 2/Phase 3 Interventional halted prematurely. Actual 7
NCT01850108 Suspended Non-Myeloablative Conditioning and Bone Marrow Transplantation N/A Interventional COVID-19 response Anticipated 25
NCT03794024 Terminated Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome Observational Manufacturer of the device filed for bankruptcy Actual 3
NCT04424576 Suspended Ovarian Morphology in Girls Observational Suspended due to COVID-19. No suspension of IRB approval. Anticipated 60
NCT01973881 Suspended Quantitative MRI for Myelofibrosis Observational Enrollment paused due to COVID-19 and will resume in the future. This is not a suspension of IRB approval. Anticipated 120
NCT03023449 Suspended Diffuse Optical Monitoring With Inhaled Nitric Oxide Phase 2 Interventional Enrollment in this study has been temporarily suspended due to the COVID-19 pandemic. Anticipated 40
NCT03161964 Terminated Propranolol in Treating Hypoglycemia Unawareness Phase 2 Interventional Statistical power could not be achieved due to low enrollment. Actual 2
NCT03224546 Suspended Cocaine Use Reduction and Health N/A Interventional COVID-19 Anticipated 250
NCT03445767 Withdrawn Structured Polypharmacy Management Before Elective Non-cardiac Surgery in Frail and Elderly People N/A Interventional Did not receive full funding to proceed Actual 0
NCT03496077 Suspended Addictive Potential of LCCs in Dual Users N/A Interventional COVID outbreak Anticipated 125
NCT03786783 Suspended Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant Phase 2 Interventional Other - Pending evaluation of patients on study currently Anticipated 45
NCT03877198 Terminated Comparison of Oxygen Controllers in Preterm InfanTs N/A Interventional As a result of a slower inclusion rate than expected, competence of medical staff to work with the AVEA ventilator could no longer be guaranteed. Actual 15
NCT03895853 Terminated Early Metabolic Resuscitation for Septic Shock Phase 2 Interventional At the request of the PI Actual 2
NCT03937986 Suspended Suvorexant and Cocaine Early Phase 1 Interventional COVID-19 Anticipated 20
NCT03954938 Suspended Behavioral Effects of Drugs (Inpatient): 38 Early Phase 1 Interventional COVID-19 Anticipated 30
NCT03960606 Suspended Study in Adult Asthmatic Patients With Allergic Bronchopulmonary Aspergillosis Phase 2 Interventional COVID-19 Pandemic Anticipated 64
NCT04203511 Withdrawn INCMGA00012 in Combination With Chemoradiation in Participants With Stage III Non-Small Cell Lung Cancer (POD1UM-301) Phase 3 Interventional Sponsor Strategic/Business Decision Actual 0
NCT04420247 Suspended Efficacy of Chloroquine or Hydroxychloroquine in Treating Pneumonia Caused by SARS-Cov-2 - COVID-19 Phase 3 Interventional WHO has recommended Chloroquine studies to be suspended for lack of efficacy. Actual 54
NCT00001219 Terminated Comparing Magnetic Resonance Imaging/Spectroscopy Techniques Observational protocol has not been used for many years and has outlived it utility Actual 49946
NCT03243058 Suspended Low-dose IL-2 in Established T1D - The "PROREG" Study Phase 1/Phase 2 Interventional Funding withdrawal and COVID-19 environment. Anticipated 60
NCT03343613 Terminated A Study of LY3381916 Alone or in Combination With LY3300054 in Participants With Solid Tumors Phase 1 Interventional Study terminated due to strategic business decision by Eli Lilly and Company. Actual 60
NCT02506114 Terminated Neoadjuvant PROSTVAC-VF With or Without Ipilimumab for Prostate Cancer Phase 2 Interventional Low Accrual Actual 15
NCT02812407 Withdrawn HRIM vs Mucosal Impedance in GERD Participants N/A Interventional No linger a clinically relevant research question Actual 0
NCT03349840 Terminated Randomised Open Label Study of Insulin Degludec Versus Insulin Glargine U100 in Ramadan Phase 4 Interventional The study was terminated by the IRB and the Institutional Official after the MOPH and WCMQ audits Actual 273
NCT03613259 Withdrawn Fluorothymidine F-18 PET in Diagnosing Patients With Intermediate or High Grade Soft Tissue Sarcoma Early Phase 1 Interventional Funding expired Actual 0
NCT03810183 Terminated A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia Phase 2 Interventional Company decision Actual 9
NCT03916146 Suspended Behavioral Parent Training for Families With Deaf and Hard of Hearing Preschoolers N/A Interventional Research activity paused for COVID-19 Anticipated 300
NCT03944551 Terminated Bubble Continuous Positive Airway Pressure for Children With Severe Pneumonia in Mali, Africa N/A Interventional Participant mortality rates were higher than expected. Actual 13
NCT04186689 Suspended Relationship Between Food Insecurity and Child Dental Anxiety Observational COVID -19 pandemic Anticipated 300
NCT04419792 Suspended 'A Profile of Physical Performance Variables in an Out-patient Adult Population With Narcolepsy' Observational Recruitment for study has been suspended due to Covid-19. Anticipated 70
NCT00985907 Terminated Doxil® + Melphalan + Velcade (DMV) in Relapsed/Refractory Multiple Myeloma Phase 1/Phase 2 Interventional Low Accrual Actual 13
NCT00393224 Terminated Defining the Clinical Utility of EBV Antibody Screening to Identify Individuals Susceptible to Nasopharyngeal Carcinoma (NPC) Within High-Risk, Multiplex NPC Families Observational Determined not to be human subject reseach Actual 952
NCT01257100 Terminated Environmental and Genetic Determinants of NPC Observational Determined not to be Human Subject Research Actual 3500
NCT02512237 Terminated A Dose-escalation Study of ARX788, IV Administered in Subjects With Advanced Cancers With HER2 Expression Phase 1 Interventional Replace with a new trial Actual 9
NCT02767934 Terminated Pembrolizumab in Treating Minimal Residual Disease in Patients With Acute Lymphoblastic Leukemia Phase 2 Interventional Terminated due to lack of efficacy Actual 12
NCT02974673 Terminated Pilot Study of Ejaculatory Dyssynergia by Electronic Microsensors of Sphincters N/A Interventional lack of recruitment Actual 11
NCT03301636 Terminated A Study of Indoximod or Placebo Plus Pembrolizumab or Nivolumab for Subjects With Unresectable or Metastatic Melanoma Phase 2 Interventional Sponsor termination, not related to efficacy, safety or feasibility. Actual 21
NCT03448133 Withdrawn rTMS for the Treatment of Primary Progressive Aphasia: A Randomized Controlled Trial N/A Interventional Because of the expiration of the previous ethical approval documents Actual 0
NCT03537547 Terminated Combinatorial Pharmacogenomics Testing in Treatment-Naïve Major Depressive Disorder Phase 4 Interventional Per sponsor and PI institution discussions Actual 6
NCT03571646 Terminated LIFEGUARD Study - Continuous Respiratory Monitoring on the General Ward N/A Interventional Poor recruitment rate due to difficulties in identifying suitable patients Actual 6
NCT03579758 Withdrawn Chemotherapy Before & After Surgery in Patients With Resectable Gallbladder Cancer Phase 3 Interventional This trial will open as an NCTN trial. Actual 0
NCT03735160 Withdrawn Pressure Over Nasotracheal Intubation Related Nasal Alar Injury Observational Technical problem Actual 0
NCT03822689 Withdrawn Comparison of Ventilation Tubes Among Anesthetized Pediatrics N/A Interventional Institutional Review Board did not approve Actual 0
NCT03869372 Suspended Cerebral Cortical Influences on Autonomic Function N/A Interventional Covid-19 Anticipated 96
NCT03918499 Suspended IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer Phase 1/Phase 2 Interventional Temporary on hold Anticipated 20
NCT03952143 Suspended A Study of LY900014 Compared to Insulin Lispro (Humalog) in Adults With Type 2 Diabetes Phase 3 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 564
NCT04084665 Withdrawn Biomarkers in Participants With Hidradenitis Suppurativa Receiving Guselkumab. Early Phase 1 Interventional COVID-19 Pandemic Actual 0
NCT04097431 Suspended Identifying Precursors to Severe Problem Behavior N/A Interventional Temporarily paused due to COVID-19 and expected to resume; not a suspension of IRB approval. Anticipated 60
NCT04118036 Suspended Abemaciclib + Pembrolizumab In Glioblastoma Phase 2 Interventional Safety concerns Anticipated 47
NCT04144127 Suspended Prostate Cancer Soccer N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 40
NCT01870869 Terminated NATRELLE® 410 X-Style and L-Style Breast Implants Continued Access Study N/A Interventional There was no indication that long-term follow-up would differ between any of the studies that have evaluated devices within the 410 Style Matrix. Actual 1951
NCT02083939 Terminated Prophylactic Antibiotic Treatment for Laparoscopic Inguinal Hernia Mesh Repair: Necessary or Not? Observational Recruitment failed Actual 5
NCT03284476 Withdrawn Post Surgically Treated Peritonitis Complications Observational No inclusion Actual 0
NCT03284489 Withdrawn Post Pancreatitis Complications Study (Based on a Prospective Data Base) Observational No inclusion Actual 0
NCT03407287 Suspended Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status Observational interim analysis Anticipated 180
NCT03744598 Terminated Self-monitoring of Spirometry & Symptoms Via patientMpower App in Idiopathic Pulmonary Fibrosis Observational Clinic visits stopped due to COVID19 Actual 21
NCT03862690 Withdrawn A Research Study, Looking at How NovoMix® Works in People With Type 2 Diabetes in Local Clinical Practice in Algeria Observational Sponsor decision Actual 0
NCT03867240 Suspended Gabapentin and Chronic Post Surgical Pain Phase 3 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 100
NCT04001231 Withdrawn Study of Exenatide Once-Weekly Suspension in Chinese Patients With Type 2 Diabetes Mellitus Phase 1 Interventional The study is stopped based upon strategic considerations impacting the clinical development of exenatide once-weekly suspension in China Actual 0
NCT04417816 Terminated Ultrasound-induced Adipose Tissue Cavitation and Training in Obesity N/A Interventional At the request of the Ethical Committee Actual 28
NCT04140877 Withdrawn Choroidal Changes Post Short Term Exposure To Virtual Reality Devices N/A Interventional Strategy change Actual 0
NCT04239534 Suspended CONVERGE CAP Study-For The Treatment Of Symptomatic Persistent or Long-standing Persistent AF N/A Interventional Start-up and enrolling activities have been temporatily suspended due to the COVID-19 pandemic. Anticipated 170
NCT04333654 Suspended Hydroxychloroquine in Outpatient Adults With COVID-19 Phase 1 Interventional Sponsor decision pending further evaluation of information related to benefit-risk Anticipated 210
NCT04347512 Withdrawn EVALUATION OF THE EFFICACY OF THE HYDROXYCHLOROQUINE-AZITHROMYCIN COMBINATION IN THE IN THE PREVENTION OF COVID-19 RELATED SDRA Phase 3 Interventional In view of the notices concerning hydroxychloroquine issued by the regulatory authorities, we withdraw the protocol Actual 0
NCT01210027 Suspended A Study of Radiation Toxicity in the Liver Using MRI-Based Perfusion Observational Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 140
NCT02045381 Suspended Optimization of MRI for Radiation Therapy Observational Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 432
NCT02250924 Withdrawn Caffeinated Gum to Prevent Post-Operative Ileus: A Prospective, Randomized, Placebo-controlled Trial N/A Interventional Investigator decision - clinical practice change Actual 0
NCT02303392 Suspended Selinexor and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Aggressive Non-Hodgkin Lymphoma Phase 1 Interventional pending amendment Anticipated 92
NCT02748746 Withdrawn Early Detection of Lymphedema With Bio-Electrical Impedance Analysis in Patients After Breast Cancer Surgery N/A Interventional Unable to achieve device(s) which will be used in this study. Actual 0
NCT03115320 Terminated Frozen-thawed Embryo Transfer in a Naturally Stimulated Cycle: Does hCG Triggering Bring Any Advantage in Comparison to Testing LH Surge With Home Tests? Phase 4 Interventional High cancellation rate in LH test group in interim analysis Actual 62
NCT03287063 Suspended Study Using Genomic, Histologic and Radiomic Analysis to Evaluate Regional Tumor Heterogeneity in Patients Undergoing Surgery for Newly Diagnosed Glioblastoma Observational Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 20
NCT03325114 Terminated Safety and Efficacy of Chlorthalidone in Type 1 Diabetes Phase 2 Interventional COVID restrictions prohibit further study activies Actual 1
NCT03941717 Suspended Testing the Effectiveness of a Parent and Child Mindfulness-Based Intervention for Child Venipuncture N/A Interventional COVID-19 restrictions Anticipated 150
NCT03970109 Suspended HLAB-002 of ANS-6637 for Alcohol Use Disorder Phase 2 Interventional Clinical Hold for Safety Anticipated 81
NCT04086342 Withdrawn CHI-902 for Treatment of Social Anxiety Disorder Phase 2 Interventional Changes in pipeline Actual 0
NCT04100629 Terminated Digital Support Intervention on Newly Licensed Nurses N/A Interventional Lack of enrollment (and due to pandemic) Actual 23
NCT04139980 Suspended Virtual Reality Device for Rehabilitation of Stroke Patients N/A Interventional staffing resources Anticipated 100
NCT04189315 Withdrawn Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease Phase 4 Interventional R&D portfolio review and in light of the global impact of the COVID-19 pandemic Actual 0
NCT04332081 Terminated Hyperbaric Oxygen for COVID-19 Patients N/A Interventional The IRB has determined that the design of this trial should be changed to a randomized controlled trial. A new record will be created for the redesigned study. Actual 20
NCT04341727 Suspended Hydroxychloroquine,Hydroxychloroquine,Azithromycin in the Treatment of SARS CoV-2 Infection Phase 3 Interventional DSMB recommended study suspension slow accrual Anticipated 500
NCT04371926 Withdrawn Prophylactic Benefit of Hydroxychloroquine in COVID-19 Cases With Mild to Moderate Symptoms and in Healthcare Workers With High Exposure Risk N/A Interventional Concerned about the adverse effects of HCQ Actual 0
NCT03536338 Terminated Spinal Stimulation Sit-to-Stand Training After Spinal Cord Injury N/A Interventional COVID-19 pandemic Actual 9
NCT04003519 Withdrawn Study to Predict Lanreotide-induced Disease Activity Normalization in Acromegaly Observational Study timeline delay, low site feasibility and delay concerns due to COVID-19. Actual 0
NCT03933930 Withdrawn Comparing the Prognosis of Lactate-directed and Goal-directed Therapy in Hyperthermic Intraperitoneal Chemotherapy. N/A Interventional No patient wants to be recruited. Actual 0
NCT04411121 Suspended Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-risk Head and Neck Cancer Phase 2/Phase 3 Interventional Scheduled Interim Monitoring Anticipated 613
NCT02842125 Terminated Safety and Efficacy of Intra-Arterial and Intra-Tumoral Ad-p53 With Capecitabine (Xeloda) or Anti-PD-1 in Liver Metastases of Solid Tumors and Recurrent Head and Neck Squamous Cell Cancer Phase 1/Phase 2 Interventional Arm C rolled into parallel study; Arms A and B halted for greater efficacy in Arm C Actual 4
NCT03610763 Suspended Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 347
NCT03637023 Suspended Virtual Reality for Parkinson's Disease N/A Interventional due to COVID-19 outbreak Anticipated 30
NCT04032158 Terminated Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis (RMS) Phase 3 Interventional Administrative reason by Sponsor. Actual 3
NCT02125331 Terminated Measurement of NonInvasive Blood Pressure in Neonates Through Adults and Special Populations Observational Data collection requirment complete Actual 83
NCT04164069 Suspended Dasatinib in Preventing Oxaliplatin-Induced Peripheral Neuropathy in Patients With Colorectal Cancer Receiving FOLFOX and Bevacizumab Phase 1 Interventional PI Decision Anticipated 20
NCT04184518 Withdrawn Durvalumab (MEDI4736) Plus Cediranib in Patients With Metastatic Uveal Melanoma Phase 2 Interventional The Cediranib producer laboratory decided to stop the development of this product. Actual 0
NCT04235270 Suspended A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants Phase 1 Interventional Occurrence of COVID-19 pandemic Anticipated 62
NCT04300413 Suspended Patient-Centered, Interprofessional Approach to Improve Functional Outcomes in a Skilled Nursing Facility N/A Interventional On hold due to COVID-19 outbreak Anticipated 53
NCT03010137 Terminated Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial N/A Interventional Lack of staff resources to properly consent and enroll patients into the study. Actual 30
NCT00001651 Terminated Use of Labeled Glucose to Study Lymphocyte Replication and Survival in HIV-Infected Patients N/A Interventional Slow/Insufficient accrual Actual 54
NCT02353000 Terminated Whole Brain Radiotherapy (WBRT) Versus Stereotactic Radiosurgery (SRS) for 4 Upto 10 Brain Metastases N/A Interventional Unable to achieve accrural within anticipated timeframe Actual 31
NCT02625376 Terminated Resveratrol for Exudative Age-Related Macular Degeneration N/A Interventional Actual 25
NCT03256331 Terminated Evaluate the Safety of BEL-X-HG in Advanced Cancer Patients Phase 1 Interventional In the light of the on-going COVID-19 pandemic and the resulted difficulty in patient recruitment. Actual 23
NCT03393806 Terminated Repeat Dose Study of GSK3772847 in Participants With Moderate to Severe Asthma With Allergic Fungal Airway Disease (AFAD) Phase 2 Interventional Recruitment was terminated early before meeting target enrolment due to a high screen failure rate and the feasibility of completing the study in a timely way Actual 18
NCT02281877 Suspended Alterations in Muscle After Total Knee Arthroplasty N/A Interventional On hold due to COVID-19 outbreak Anticipated 20
NCT02898753 Terminated VAL-1221 Delivered Intravenously in Ambulatory and Ventilator-free Participants With Late-Onset Pompe Disease Phase 1/Phase 2 Interventional Company closure due to lack of funding Actual 12
NCT03054961 Suspended Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study Observational Protocol Amendment in process, pending reengineering of intruments Anticipated 40
NCT03274817 Terminated A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol Phase 1 Interventional Insufficient Enrollment Actual 5
NCT03410056 Terminated Safety and Efficacy of AMG 592 in Subjects With Active Rheumatoid Arthritis Phase 1/Phase 2 Interventional Amgen made a business decision not to proceed with Phase 2. Actual 36
NCT04415372 Suspended Macromolecular Imaging of White and Gray Matter Pathology in Multiple Sclerosis Observational Suspended due to COVID-19 Anticipated 50
NCT03629249 Terminated Systemic Corticosteroids Avoidance Study in Severe Asthma Patients Phase 3 Interventional Company decision Actual 609
NCT03713099 Withdrawn NEUWAVE Flexible Probe Study #2 N/A Interventional Changed study design prior to any patients enrolled. Actual 0
NCT04017637 Withdrawn Resistance Training Intervention to Promote Lean Mass in Youth With IBD N/A Interventional Study cancelled Actual 0
NCT04002882 Suspended Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF) Observational Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 90
NCT04116229 Suspended Cognition and Magnetic Resonance Imaging of Brain Inflammation in Obesity Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 20
NCT02872935 Terminated Minimizing Nausea and Vomiting During Spinals for CS Phase 4 Interventional Actual 22
NCT00933829 Terminated Comparison of Cosmetic Outcomes of Lacerations Repaired Using Absorbable Versus Non-absorbable Sutures N/A Interventional Actual 160
NCT01126853 Withdrawn Combination Hepatitis A and B Vaccine to Induce Immunity in Non-responders Phase 4 Interventional Actual 0
NCT02765516 Terminated Genetic Basis for Prediction of Non-responders to Dietary Plant Sterol Intervention N/A Interventional Inability to recruit Actual 43
NCT03165968 Suspended Test and Evaluation of Non-Invasive Neuro-Assessment Devices (NINAD): NeuroKinetics, Inc, iPAS Observational COVID19 epidemic, and institutional guidelines for halt of recruitment during epidemic Anticipated 150
NCT03357042 Withdrawn Evaluation of a Physical Intervention for Persistent Post-Concussive Symptoms N/A Interventional researchers did not find participants to meet the inclusion and exclusion criteria for the testing protocols Actual 0
NCT03790865 Terminated Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome Phase 2/Phase 3 Interventional Livoletide did not result in a statistically significant improvement in hyperphagia and food-related behaviors Actual 158
NCT03953521 Terminated Neuronavigated TBS in Depression N/A Interventional Interim analysis indicated no statistical difference between treatment arms. Actual 37
NCT04032171 Terminated Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis Phase 3 Interventional Administrative reason by Sponsor. Actual 1
NCT04092257 Suspended HPV-Based Screen-and-Treat Demonstration Project in Lilongwe N/A Interventional The study was about to start recruiting but in response to COVID-19, screening and enrollment has been put on hold. Anticipated 625
NCT04114630 Withdrawn Study of Quality of Life in Subjects With Chronic or High-frequency Episodic Migraine and Associated Comorbidities Treated With Erenumab Phase 3 Interventional No patients were enrolled and global prioritization of pipeline and research strategy Actual 0
NCT02766478 Suspended Genistein Supplementation to Mitigate Cardiometabolic Dysfunction in Patients Undergoing Androgen Deprivation Therapy for Prostate Cancer Phase 2 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 24
NCT04174794 Terminated Investigating Reduction of aCute heArt Failure Readmission With Lung UltraSound-preliminary Trial Observational COVID-19 Pandemic Actual 43
NCT02813668 Suspended Worksite Lifestyle Program for Reducing Diabetes and Cardiovascular Risk in India N/A Interventional Study activities involving participants are suspended due to COVID-19 Actual 2065
NCT04198844 Withdrawn The Effectiveness and Safety of Apixaban in NVAF Patients With History of Osteoporosis and/or Fracture: A Nation-wide Population Based Study Observational Interaction term analysis result was not significant and thus comparative effectiveness for primary and secondary outcomes could not be considered per protocol. Actual 0
NCT04205890 Withdrawn Intravenous Ketamine Effects on Functional Neuroanatomy Phase 1 Interventional Sponsor is no longer interested in funding the study Actual 0
NCT04332549 Withdrawn To Assess the Bioavailability and Safety of Paclitaxel Injection Concentrate for Suspension in Subjects With Locally Recurrent or Metastatic Breast Cancer Phase 1 Interventional After meeting with the FDA, SPARC concludes a BE study will not be required Actual 0
NCT04334967 Suspended Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care Phase 4 Interventional suspected unfavorable risk/benefit assessment Actual 13
NCT03307057 Suspended Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families N/A Interventional The study activities are on hold due to COVID Anticipated 250
NCT02946437 Withdrawn Sevoflurane in Subarachnoidal Haemorrhage Phase 2 Interventional Patients failed to be enrolled because of tight exclusion criteria. Actual 0
NCT03595748 Suspended Peer Mentorship to Improve Outcomes in Patients on Maintenance Hemodialysis N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval Anticipated 200
NCT04413487 Withdrawn Early Detection of Heart Problems in Cancer Patients Receiving Chemotherapy Observational Study never started due to change in standard of care guideline Actual 0
NCT03999190 Withdrawn Imaging Dopamine D2 Agonist Binding Sites in Schizophrenia Observational investigational radiotracer was not approved Actual 0
NCT04003935 Terminated Juice Plus Inflammaging and Cardiovascular Disease Prevention Study Observational One of the 2 nutritional products is reformulated and withdrawn from the market Actual 22
NCT04041596 Withdrawn Degree of Benefit From Low-Frequency Acoustic Amplification Using the Advanced Bionics Acoustic Earhook Phase 4 Interventional Due to a lack of enrollment Actual 0
NCT04162431 Suspended DOLPHIN-VIVO: Diagnosis Of LymPHoma IN Vivo (Ex Vivo Phase) Observational Covid19 Anticipated 250
NCT04213014 Suspended Guys/Girls Opt for Activities for Life Trial (GOAL) to Increase Young Adolescents' Physical Activity and Healthy Eating Phase 3 Interventional Recruitment halted due to COVID19 Anticipated 1760
NCT04289883 Withdrawn Food Structure and Satiety N/A Interventional The Covid-19 pandemic that made it impossible to conduct within the timeframe. Actual 0
NCT04407832 Withdrawn Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy N/A Interventional Actual 0
NCT03235986 Terminated A Study To InvestigateThe Safety, Tolerability And Efficacy Of Nebulised Curosurf® In Preterm Neonates With Respiratory Distress Syndrome (RDS) Phase 2 Interventional Change in the benefit-risk balance Actual 166
NCT03654755 Terminated Study to Evaluate Long-Term Safety of ASN002 in Subjects With Moderate to Severe Atopic Dermatitis Phase 2 Interventional Phase 2 study results Actual 168
NCT03728504 Terminated Study to Evaluate ASN002 in Subjects With Moderate To Severe Chronic Hand Eczema Phase 2 Interventional Primary Endpoint completed and continuing visit schedule complications due to COVID-19 Actual 19
NCT03770299 Withdrawn An Investigational Immuno-therapy Study of Nivolumab Given After Surgery in Non-Small Cell Lung Cancer (NSCLC) Participants With Minimal Residual Disease Phase 2 Interventional Business objectives have changed Actual 0
NCT02281344 Terminated MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants Phase 1 Interventional Inconsistent and unpredictable exposures were observed. Drug needed to be reformulated. Actual 6
NCT02667327 Terminated A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer Phase 3 Interventional Sponsor Decision (No safety or efficacy concerns) Actual 124
NCT02744612 Suspended Ibrutinib and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma Phase 2 Interventional Anticipated 39
NCT02860078 Suspended Epidural Injection of Corticosteroids Under USG (EICUS) N/A Interventional Not started Anticipated 30
NCT02924389 Suspended Dolutegravir in Reservoirs N/A Interventional Enrollment and study visits are temporarily suspended due to COVID-19. Anticipated 40
NCT02975128 Terminated Minimal Invasive Breast Cancer Excision Using the Breast Lesion Excision System Under Ultrasound Guidance N/A Interventional Needle production stopped Actual 22
NCT03318107 Terminated Ultrasound and Photoacoustic Imaging for Cervical Cancer N/A Interventional Low accrual Actual 2
NCT03335020 Withdrawn Using Ultrasonography, Shear Wave Elastography, Strain Imaging, and 3-D Volume Ultrasonography on Cardiovascular Disease Phase 1 Interventional Closed by Investigator Actual 0
NCT03342911 Suspended Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery Phase 2 Interventional COVID-19 Anticipated 37
NCT03418532 Terminated MP0250 DARPin® Protein Plus Osimertinib in Patients With EGFR-mutated NSCLC Phase 1/Phase 2 Interventional Sponsor's decision Actual 8
NCT03457025 Withdrawn Effect of Adjuvant Hyperbaric Oxygen Therapy on Bells Palsy Outcome Early Phase 1 Interventional lack of enrollment Actual 0
NCT03492138 Terminated Ixazomib, ONC201, and Dexamethasone in Relapsed/Refractory Multiple Myeloma Phase 1/Phase 2 Interventional Low enrollment Actual 5
NCT03551119 Suspended Physical Activity in Renal Disease (PAIRED): The Effect on Hypertension Phase 3 Interventional Covid-19 pandemic Anticipated 160
NCT03648216 Suspended The Effect of Experimentally Increasing Sedentary Behaviour on Subjective Well-being N/A Interventional Recruitment and study progress halted by COVID-19 Anticipated 46
NCT03968835 Withdrawn A Comparison of the Outcomes of Distal Fingertip Amputations Treated With Either Artificial (Xeroform) or Biological Dressings Observational lack of enrollment Actual 0
NCT03970356 Suspended Improving Antibiotic Prescribing for Urinary Tract Infections in Frail Elderly N/A Interventional Study paused due to Covid-19 outbreak Anticipated 680
NCT02149823 Suspended Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations Phase 1 Interventional COVID-19 Anticipated 165
NCT02532517 Terminated Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device N/A Interventional No safety issues; change in innovation strategy Anticipated 320
NCT02694341 Withdrawn Bakri Balloon in Placenta Previa N/A Interventional No participants shared Actual 0
NCT02866279 Suspended Immediate Postpartum Contraceptive Implant Placement and Breastfeeding Success in Women at Risk for Low Milk Supply: A Non-inferiority Trial N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 375
NCT02923986 Withdrawn Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDS Phase 1/Phase 2 Interventional No enrollment Actual 0
NCT03036319 Suspended Patient-Centered NeuroRehabilitation (PCN) N/A Interventional Enrollment and interactions/interventions are temporarily paused due to COVID-19 and are expected to resume in the future. Anticipated 500
NCT03451851 Suspended A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants Phase 3 Interventional Enrollment Hold due to COVID-19 Anticipated 125
NCT03341000 Terminated Pilot Study to Examine the Feasibility of the Dynamic Interferential Spinal Cord Stimulation System™ (DISCSS™) N/A Interventional Sponsor Decision Actual 18
NCT03395119 Suspended Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects Phase 1 Interventional Suspended due to COVID-19 risks Anticipated 60
NCT03517995 Withdrawn Randomized, Phase II Clinical Trial of Sulforaphane in Bladder Cancer Chemoprevention Phase 2 Interventional Grant not approved Actual 0
NCT03520309 Suspended Clinical Criteria for the Evaluation of Caries Lesions Around Restorations in Primary Teeth (CARDEC-03) N/A Interventional Follow-ups paused temporarily since March 16th due to COVID-19 Actual 163
NCT04016116 Withdrawn Dual PD-1 and JAK2 Inhibition in Hematological Malignancies Phase 2 Interventional PI left the institution Actual 0
NCT03630367 Suspended Effects of L‑Carnitine Supplementation on Respiratory Distress Syndrome Phase 4 Interventional Unavailability of the medication Anticipated 300
NCT03717532 Terminated Blood Flow Restriction Therapy in Patellofemoral Pain Syndrome N/A Interventional Inadequate/low enrollment Actual 1
NCT03729310 Withdrawn Comparison of Two Steroid Nasal Implants Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis Early Phase 1 Interventional No participants enrolled Actual 0
NCT04404348 Suspended Cognitive Rehabilitation for Opioid Abuse-related Cognitive Impairment N/A Interventional Study halted due to Covid-19 precautions Anticipated 50
NCT04056637 Terminated Choice of Modality of Follow up for Medication Abortion N/A Interventional COVID-19 Impacted Service Delivery and Research Infrastructure Actual 26
NCT04074304 Suspended Developing and Piloting a Multi-component Technology-based Care Intervention to Address Patient Symptoms and Caregiver Burden in Home Hospice. Phase 1. N/A Interventional Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval Anticipated 30
NCT04123197 Suspended Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis N/A Interventional The study activities are suspended due to COVID Anticipated 300
NCT02515669 Terminated Study of an Investigational Drug, RO7239361 (BMS-986089), in Ambulatory Boys With DMD Phase 1/Phase 2 Interventional A pre-planned futility analysis indicated lack of efficacy. Actual 43
NCT04179721 Suspended Reducing Behavioral and Psychological Symptoms of Dementia N/A Interventional COVID-19; study will resume when restrictions are lifted. Anticipated 158
NCT04230720 Suspended Effect of Artificial Tears on Biometry Phase 4 Interventional Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 30
NCT04404790 Suspended Antiplatelet Thrombolysin (Anfibatide) Phase 1 Clinical Trial in Healthy Volunteers Phase 1 Interventional Optimization of protocol Anticipated 50
NCT04409314 Suspended Hypoxia-Specific Imaging to Predict Outcomes of Chimeric Antigen Receptor T-cell Therapy Observational Drug Supply Anticipated 30
NCT01263652 Withdrawn Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine Patients N/A Interventional inability to complete recruitment as planned Actual 0
NCT03132064 Suspended The Association Between Pre-operative Pain Psychology and Hypersensitivity With Poor Functional Outcome After Knee Replacement. Observational COVID-19 Anticipated 50
NCT03611296 Suspended Translational Investigation of Growth and Everyday Routines in Kids (TIGER Kids) Fitness Ancillary Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Actual 30
NCT04341610 Withdrawn ASC Therapy for Patients With Severe Respiratory COVID-19 Phase 1/Phase 2 Interventional Not approved by ethical committee Actual 0
NCT02430649 Withdrawn Irreversible Electroporation(IRE) For Unresectable Prostatic Neoplasms N/A Interventional Actual 0
NCT03699644 Suspended Multimodal Ocular Imaging in Neurodegeneration N/A Interventional Enrollment/interactions/interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 50
NCT04402775 Terminated Brachiocephalic Arteriovenous Fistulae: Two Different Techniques of Bloodless Surgery and Their Effect on Fistula Stenosis. N/A Interventional Due to a low inclusion rate Actual 25
NCT04406610 Terminated CAR-T Cell Immunotherapy for GD2 Positive Glioma Patients Phase 1/Phase 2 Interventional Actual 2
NCT02557529 Terminated Progressive Resistance Training in Head and Neck Cancer Patients During Concomitant Chemoradiotherapy N/A Interventional Slow recruition Actual 50
NCT02897713 Suspended Feasibility, Safety, and Outcomes of Intensive Enteral Nutrition in Patients With Mechanical Ventilation N/A Interventional Similar study has been published. Anticipated 400
NCT04128436 Terminated The Effect of Luteal Blood Progesterone Levels on Ongoing Pregnancy Rates N/A Interventional With the interim analysis, a marked decrease in ongoing pregnancy rate was noted in patients with a drop in serum progesterone level from OPU+3 day to OPU+5 day Actual 126
NCT04402294 Suspended Individualized Closed Loop TMS for Working Memory Enhancement N/A Interventional COVID-19 Restrictions Anticipated 38
NCT03495427 Suspended PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores Phase 2/Phase 3 Interventional Compounding facility to submit quality update before they can manufacture 18F-DCFPyL Anticipated 60
NCT02545283 Terminated A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) Phase 3 Interventional The study was stopped for futility based on efficacy results at the interim analysis; no unexpected safety findings were observed. Actual 447
NCT03551717 Terminated Retinal Microvascularization and Cardiovascular Disease Observational Lack of inclusion Actual 155
NCT03575507 Withdrawn Non-invasive Improvement of Buttocks With Magnetic Device N/A Interventional It wasn't possible to recruit the desired number of patients. Actual 0
NCT03812341 Withdrawn SINGLE PATIENT EXPANDED ACCESS OF A PROSPECTIVE, MULTICENTER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND PROBABLE BENEFIT OF THE KERAKLEAR NON-PENETRATING KERATOPROSTHESIS IN SUBJECTS WITH CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT N/A Interventional No enrollment Actual 0
NCT03946774 Suspended Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 20
NCT04069260 Terminated A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis Phase 2 Interventional Due to study design limitations, this study has been discontinued and will not proceed with the 2nd cohort as contemplated in the original protocol. Actual 3
NCT04141046 Suspended LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE N/A Interventional Suspended due to COVID-19 risks Anticipated 72
NCT04207905 Suspended Evaluation of the Healthy Michigan Plan Section 1115 Community Engagement Requirement Waiver Observational On 3/4/20 a federal judge ruled the HMP work requirement unlawful, thereby ending it and suspending implementation of this RCT. This is not an IRB suspension. Anticipated 229000
NCT04306861 Suspended Novel MRI Techniques for Pancreatic Cancer Observational Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 20
NCT04350450 Withdrawn Hydroxychloroquine Treatment of Healthcare Workers With COVID19 Illness at Montefiore Phase 2 Interventional PI withdrew the submission to the IRB Actual 0
NCT04377737 Withdrawn Incidence of Covid-19 in School Children N/A Interventional Human Subjects Protection Review: submitted, denied Actual 0
NCT01805973 Terminated Surviving Aneurysm Surgery: A Pilot Study on Exercise Training in Abdominal Aortic Aneurysm Patients N/A Interventional Anticipated 100
NCT02636387 Terminated Desmopressin as a Therapy for Bedwetting in Children With Sickle Cell Disease Observational Low recruitment Actual 14
NCT02816437 Withdrawn FMT for MDRO Colonization in Solid Organ Transplant Phase 1 Interventional safety Actual 0
NCT03115151 Suspended Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery Phase 4 Interventional COVID-19 policy Anticipated 58
NCT03348280 Suspended Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics Observational temporarily paused due to Covid-19 and expected to to resume, this is not a suspension of IRB approval. Anticipated 40
NCT03438435 Suspended Fluorescence QRH-882260 Peptide Imaging in the Bile Duct Phase 1 Interventional Enrollment and interactions/interventions temporarily paused due to COVID-19 & may resume in the future. No suspension of IRB approval. Anticipated 12
NCT03453658 Suspended Mechanized Instrumentation for Endodontic Treatment of Primary Teeth N/A Interventional Follow-ups paused temporarily since March 16th, 2020 due to COVID-19. Anticipated 150
NCT03579147 Withdrawn Non-invasive Buttock Lifting Induced by Magnetic Device - Multicentric Study N/A Interventional It was not possible to recruit any patients at that time. Actual 0
NCT03610347 Terminated Paclitaxel Eluting Balloon After Bare Metal Stent Implantation vs. Drug-Eluting Stent in St Elevation Myocardial Infarction N/A Interventional Low recruitment Actual 199
NCT03844750 Suspended Pembrolizumab After Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and Who Are Undergoing Liver Surgery Phase 2 Interventional Pending Amendment Anticipated 19
NCT03852576 Suspended Phase 1B Study of KSP/QRH Dimer for Detection of Neoplasia in the Esophagus Phase 1 Interventional Enrollment and interactions/interventions temporarily paused due to COVID-19 & will resume in the future. No suspension of IRB approval. Anticipated 50
NCT03856125 Withdrawn Percutaneous Electrical Stimulation on Radial Nerve in Patients With Lateral Epicondylalgia N/A Interventional Covid19 locked down Actual 0
NCT03896477 Suspended Phase 3 Study of 10-valent Pneumococcal Conjugate Vaccine (PNEUMOSIL) Administered in a 2+1 Schedule to Healthy Infants Phase 3 Interventional Temporarily halted some in-person research activities due to COVID-19 pandemic Actual 660
NCT04044391 Terminated Use of Magnetocardiography in Evaluation of Patients Going for Cardiac Catheterization Observational Study was defunded. Actual 101
NCT04114656 Suspended Effects of Intravenous GSK3858279 on a Battery of Evoked Pain Tests in Healthy Volunteers Phase 1 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 24
NCT04175600 Suspended A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension Phase 3 Interventional Due to COVID-19 pandemic, a decision was made on 01Apr2020 to temporarily suspend further screening Anticipated 237
NCT04009850 Suspended Impact of Cigarette and E-cigarette Flavors on Adult Smoking Behavior N/A Interventional Temporarily suspended due to COVID-19 pandemic. Anticipated 50
NCT04117607 Terminated Safety and Pharmacokinetics of Rezafungin Phase 1 Interventional Stopped due to the formation of injection site skin nodules. Actual 14
NCT04241159 Withdrawn Study to Explore the Safety and Feasibility of Allogeneic Young Plasma Infusion in Older Adults Early Phase 1 Interventional Protocol required revisions and application was withdrawn from the IRB. Actual 0
NCT02608229 Terminated BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer Phase 1 Interventional Adverse events Actual 18
NCT04399291 Suspended Vitamin D Status and Bone Health of Older Adults in Care Facilities Observational COVID-19, study status being reviewed on an ongoing basis. Anticipated 200
NCT02940457 Withdrawn Cognitive Ability Training for Seniors With Mild Cognitive Impairment N/A Interventional The employe for the study quit and a new grant proposal was not financed Actual 0
NCT03779802 Terminated Prospective Multicentric Study Comparing the Acute Hemodynamic Effect of Three Modes of Stimulation in Cardiac Resynchronization Therapy Recipients N/A Interventional With the current health situation, we do not anticipate a significant resumption of recruitment for several months. Actual 50
NCT04010448 Suspended A Trial to Assess the Safety, Immunogenicity and Efficacy of a Trivalent Rotavirus P2-VP8 Subunit Vaccine in Prevention of Severe Rotavirus Gastroenteritis in Healthy Infants in Africa and India Phase 3 Interventional temporarily halted due to COVID-19 Anticipated 8200
NCT04248335 Suspended Effect of Obesity on Proton Pump Inhibitors Phase 4 Interventional Suspended due to COVID-19; No suspension of IRB approval Anticipated 150
NCT04307693 Terminated Comparison of Lopinavir/Ritonavir or Hydroxychloroquine in Patients With Mild Coronavirus Disease (COVID-19) Phase 2 Interventional Terminated early because no patients were further enrolled since mid-Apr 2020. Actual 65
NCT03354637 Terminated A Study of ATI-50002 Topical Solution for the Treatment of Alopecia Areata Phase 2 Interventional The double-blind primary endpoint was not met. Open Label Extension period halted as a result. Actual 129
NCT02931110 Suspended Study of IV CBL0137 in Previously Treated Hematological Subjects Phase 1 Interventional Business reasons Anticipated 230
NCT03137199 Terminated Allogeneic Human Cells (hMSC) Via Intravenous Delivery in Patients With Mild Asthma Phase 1 Interventional First cohort completed. Per sponsor decision. Actual 3
NCT03479905 Suspended The Use of High Flow Nasal Cannula, Standard Face Mask and Standard Nasal Cannula in Morbidly Obese Patients N/A Interventional COVID-19 policy Anticipated 216
NCT03716466 Suspended Evaluation of Prophylactic Endotracheal Intubation Observational Suspended due to covid-19 policy Anticipated 100
NCT04020042 Suspended Epidural Placement Using Handheld Ultrasound Device vs. Traditional Landmark Palpation N/A Interventional COVID-19 policy Anticipated 300
NCT04247009 Suspended Postprandial Inflammation in Rheumatoid Arthritis N/A Interventional Due to risk for covid-19 spreading, the study was suspended 12 march 2020. Anticipated 80
NCT04328350 Suspended Social Experiences of Adolescents and Young Adults With Cancer Observational Required COVID-19 related change Anticipated 200
NCT04354714 Withdrawn Ruxolitinib to Combat COVID-19 Phase 2 Interventional Could not make FDA required changes Actual 0
NCT03624192 Terminated RES Prepared With RECELL® Compared to Conventional Care for Healing of Donor Sites in Ages 1-16 Years N/A Interventional Study closed in response to COVID-19 and overall program objectives. Actual 3
NCT04093648 Withdrawn T Cells co- Expressing a Second Generation Glypican 3-specific Chimeric Antigen Receptor With Cytokines Interleukin-21 and 15 as Immunotherapy for Patients With Liver Cancer (TEGAR) Phase 1 Interventional The key elements of this study were incorporated into another study. Actual 0
NCT02830438 Terminated Shear Wave Elastography in Native Kidney Disease N/A Interventional Not enough participants recruited Actual 8
NCT00601939 Suspended Effectiveness of Empowerment Group Sessions for Treating Suicidal African American Women in Abusive Relationships N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 397
NCT01490827 Terminated Argus® II Retinal Prosthesis System Post-Market Surveillance Study Observational Sponsor discontinued the Argus II product Actual 52
NCT01574664 Withdrawn Evaluation of RFID Localization System for Marking and Retrieving Breast Lesions Observational Not required to be registered Actual 0
NCT01627301 Suspended Sympathetic Overactivity in Post-traumatic Stress Disorder N/A Interventional The study activities are suspended due to COVID-19 Anticipated 100
NCT01947673 Suspended Mechanisms of Intradialytic Hypertension N/A Interventional Study activities are suspended due to COVID-19 Anticipated 100
NCT02204904 Terminated Observational Study to Evaluate Allogeneic HSCT Outcomes for Cerebral Adrenoleukodystrophy (CALD) Observational Sufficient enrollment for Month 24 safety and efficacy endpoints Actual 59
NCT02411773 Suspended Sympatholysis in Chronic Kidney Disease Phase 2 Interventional Study activities are temporarily suspended due to COVID-19. Anticipated 110
NCT02562092 Suspended The Georgia Latino AIDS/HIV Diagnosis and Linkage in Youth (GLADLY) Project N/A Interventional Enrollment and study visits are temporarily suspended due to COVID-19. Anticipated 112
NCT02624258 Terminated Pilot Study of Non-Viral, RNA-Redirected Autologous T Cells in Patients With Refractory or Relapsed Hodgkin Lymphoma Early Phase 1 Interventional Principal Investigator decision to stop trial Actual 2
NCT02641509 Terminated Accuracy in Resection of Non-pedunculated Colonic Lesions 5-20 mm With/Without Using NBI N/A Interventional Actual 113
NCT02818959 Terminated First in Man Study of the JenaValve TAVI Plus System Transfemoral N/A Interventional Due to inability to recruit sufficient sample size in reasonable time frame. Actual 7
NCT02947750 Suspended Neurovascular Transduction During Exercise in Chronic Kidney Disease Phase 2 Interventional Study activities are temporarily suspended due to COVID-19. Anticipated 150
NCT03074695 Suspended DPE Technique in Labor Epidural for Morbidly Obese Women Phase 4 Interventional COVID 19 Pandemic Anticipated 130
NCT03265249 Suspended BRIDGE Device for Post-operative Pain Control N/A Interventional COVID-19 Restrictions Anticipated 50
NCT03565406 Terminated A Phase 1b Study of the Selective HDAC Inhibitor Mocetinostat in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma Phase 1 Interventional recruiting or enrolling participants has halted prematurely and will not resume; participants are no longer being examined or treated Actual 11
NCT03677284 Suspended Managing Time With Dementia: Effects of Time Assistive Products in People With Dementia N/A Interventional Due to the situation of virus Covid-19, recruitment is paused from 7th April. Anticipated 74
NCT03783650 Suspended Boosting Primary Care Awareness and Treatment of Childhood Hypertension N/A Interventional Temporarily paused due to COVID-19 and expected to resume. Anticipated 64
NCT03805438 Suspended ED90 of 3% Chloroprocaine for Cervical Cerclage Phase 4 Interventional COVID 19 Pandemic Anticipated 40
NCT03890419 Suspended Opioid Sparing Potential of Light-Induced Analgesia N/A Interventional COVID-19 restrictions Anticipated 90
NCT04040751 Suspended Carepartner Collaborative Integrated Therapy in Sub-Acute Stroke N/A Interventional Enrollment is suspended due to COVID-19, prescreening continues for future enrollment. Anticipated 36
NCT04068272 Suspended Safety of Bosentan in Type II Diabetic Patients Phase 1 Interventional Covid 19 general restrictions in Spain - Will eventually be resumed Anticipated 22
NCT04072367 Withdrawn FIrst-Pass Reperfusion With the NeVa Stent-Retriever Trial N/A Interventional The study was withdrawn due to a change in company strategy. Actual 0
NCT00900575 Suspended Cervical Cancer Detection Using Optical Spectroscopy N/A Interventional COVID-19 Anticipated 350
NCT02469129 Suspended PET Imaging of PARP Activity in Cancer Early Phase 1 Interventional Suspended due to COVID19 Anticipated 50
NCT02604277 Suspended Suicidal Behavior in Patients Diagnosed With Bipolar Disorder N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 130
NCT02720185 Suspended Window of Opportunity Trial of Dasatinib in Operable Triple Negative Breast Cancers With nEGFR Phase 2 Interventional Recruitment suspended due to COVID-19 Anticipated 19
NCT02788214 Terminated Helicobacter Pylori Genome Project Observational research determined not to be human subject research Actual 821
NCT03078192 Suspended Non-Invasive Diagnosis of Pulmonary Vascular Disease Using Inhaled 129Xe Magnetic Resonance Imaging Phase 2 Interventional suspended for this protocol due to the pandemic Anticipated 127
NCT03138564 Suspended An Effectiveness-Implementation Trial of SPIRIT in ESRD N/A Interventional Enrollment is temporarily suspended due to COVID-19. Anticipated 800
NCT03206125 Terminated NCI UNC Project ESCC Observational determined not to be human subjects research Actual 648
NCT03342157 Terminated Docusate/Senna for the Treatment of Diabetic Gastroparesis Phase 2 Interventional low enrollment Actual 2
NCT03342235 Withdrawn Excimer Laser Surgery for Anisometropic Amblyopia N/A Interventional Study not started due to lack of recruitment potential. Actual 0
NCT03367312 Suspended Assessing Response to Inhaled Prostacyclin With Hyperpolarized Xe MRI Phase 2 Interventional suspended for this protocol due to the pandemic, Anticipated 12
NCT03415022 Suspended Computer-Based Treatment for Social Anxiety Disorder N/A Interventional Due to COVID19 Pandemic Anticipated 40
NCT03506620 Withdrawn The Role of Nerve Blocks in Hip Arthroscopy Phase 4 Interventional Unforeseen cost restrictions of the drug halted the execution of this study altogether. Actual 0
NCT03533465 Suspended Understanding the Role of Sleep in Complicated Grief N/A Interventional Due to funding limitations Anticipated 10
NCT03574792 Suspended Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy N/A Interventional Temporarily Suspended due to COVID-19 Anticipated 60
NCT03631680 Suspended The Role of Estrogen in Adipocyte Remodeling Following Surgical Menopause Observational Temporarily paused due to COVID-19 and expected to resume. Anticipated 10
NCT03650881 Withdrawn The Comparative Efficacy of an Over the Counter Light Therapy Mask vs Over the Counter Topical Benzoyl Peroxide 2.5% and Used in Combination With Over the Counter Adapalene Gel 0.1% for Mild to Moderate Acne N/A Interventional no eligible subjects were enrolled Actual 0
NCT03651869 Suspended Effects of Nicotine in Tobacco Smokers Phase 1 Interventional Study recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 220
NCT03686813 Suspended Sildenafil for Swimming-Induced Pulmonary Edema (SIPE) Prevention Phase 2 Interventional Due to COVID-19 pandemic research stoppage Anticipated 20
NCT03742817 Suspended Effects of e-Cigarettes on Perceptions and Behavior N/A Interventional Study recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 40
NCT03751358 Terminated ESP Volunteer LA Spread Controlled by MRI N/A Interventional Problem with MRI interpretation Actual 8
NCT03781388 Suspended ED90 for Hyperbaric Bupivacaine in Super Obese Parturients Phase 4 Interventional COVID 19 Pandemic Anticipated 40
NCT03856268 Suspended Understanding the Roles of Hormones in Adipocyte Remodeling Following Menopause Observational Temporarily paused due to COVID-19 and expected to resume. Anticipated 12
NCT03933956 Suspended Metabolic Effects of the SGLT-2 Inhibitor Empagliflozin in Patients With Diabetic Nephropathy (MEDiaN) Phase 3 Interventional The study will be temporarily suspended due to the COVID-19 situation. Anticipated 40
NCT03966144 Withdrawn RoboHear™ Device: Advanced Haptic Technology That Allows the Deaf to Understand Speech N/A Interventional Company discontinued study and closed. No participants were enrolled. Actual 0
NCT04013880 Suspended ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia Phase 1/Phase 2 Interventional Paused for COVID 19 Response Anticipated 80
NCT04053452 Suspended Peripheral Nerve Ultrasound for Diagnosis and Prognosis of Guillain-Barre Syndrome N/A Interventional Due to COVID-19 restrictions Anticipated 50
NCT04107181 Suspended Pilot Study for Speculum Free Cervical Cancer Screening N/A Interventional COVID-19 Anticipated 305
NCT04333498 Suspended Use of Antiretroviral (ARV) Drug Levels in Dried Blood Spots (DBS) to Assess and Manage ART Adherence in South Africa N/A Interventional Due to COVID19 Pandemic Anticipated 60
NCT04399031 Suspended Effects of e-Cigarettes on Perceptions and Behavior - Substudy 1 N/A Interventional Study recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 200
NCT04395638 Suspended Replenishing and Maintaining Vitamin D Status in Older Adults in Residential Care Facilities in NI N/A Interventional COVID-19 study status being reviewed on an ongoing basis. Anticipated 40
NCT03588806 Terminated Use of Xtampza ER to Overcome Difficulties in Swallowing Opioid Pills Phase 4 Interventional Study halted permanently and will not resume; participants are no longer being examined or receiving intervention. Actual 11
NCT02687165 Terminated Uncovering Neural and Immune Mechanisms of Chronic Pain in Post Treatment Lyme Syndrome N/A Interventional Slow recruitment due to strict inclusion/exclusion criteria Actual 4
NCT01796470 Terminated Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic Malignancies Phase 2 Interventional Study was terminated due to safety measures. Actual 66
NCT03610048 Terminated A Long Term Study of ALKS 5461 in the Treatment of Refractory Major Depressive Disorder (MDD) Phase 3 Interventional Sponsor Decision Actual 175
NCT04066790 Terminated Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer Phase 2 Interventional We terminated this trial and initiated a new one including pertuzumab. Actual 12
NCT04249596 Suspended Tianeptine for Treatment Resistant Depression Phase 4 Interventional Due to COVID-19 Pandemic Anticipated 75
NCT04396834 Terminated Mechanisms of Lorcaserin for Smoking Cessation Phase 2 Interventional Medication removed from the U.S. market by the The Food and Drug Administration Actual 3
NCT04396847 Terminated Laboratory Screening of Lorcaserin for Alcohol Use Disorder Phase 2 Interventional Medication removed from the U.S. market by the The Food and Drug Administration Actual 5
NCT00903266 Suspended Melodic-Intonation-Therapy and Speech-Repetition-Therapy for Patients With Non-fluent Aphasia Phase 3 Interventional Covid-19 Pandemie Anticipated 30
NCT02201355 Suspended Hypofractionated Reduced-Volume Chemoradiation for T1/2N0-2 SCC Head and Neck Phase 1 Interventional PI LEFT THE DEPARTMENT Anticipated 60
NCT03104335 Withdrawn Apatinib for Advanced Soft Tissue Sarcoma Patients: a Phase 2, Multicenter Trial Phase 2 Interventional Not enough patients Actual 0
NCT03150420 Terminated A Phase 3 Clinical Trial of Intravenous Sodium Thiosulfate in Acute Calciphylaxis Patients Phase 3 Interventional Inability to accrue subjects that met the exclusion criterion "Any prior (within the past 30 days) or current Sodium Thiosulfate treatment". Actual 29
NCT03342300 Withdrawn Pegylated Liposomal Doxorubicin Versus Pirarubicin Plus Ifosfamide, Dacarbazine in Locally Advanced, Unresectable or Metastatic Soft-tissue Sarcoma Phase 2/Phase 3 Interventional No participants enrolled Actual 0
NCT03440008 Suspended Improving the Detection, Classification and Treatment of Misaligned Arthritic Ankles Observational ORD hold on non-treatment participant visits re: COVID19 Anticipated 110
NCT03476642 Suspended Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks Phase 4 Interventional Temporarily suspended due to Pandemic. Anticipated 24
NCT03655119 Suspended PES Family Support and Follow-Up Program N/A Interventional Enrollment and interventions are temporarily paused due to COVID-19 and are expected to resume in the future.This is not a suspension of IRB approval. Actual 229
NCT03694197 Terminated Long Term Safety Study of PRALUENT Phase 4 Interventional The primary objective (to evaluate the long-term safety of Praluent) was adequately evaluated in other studies. Actual 1389
NCT03694548 Suspended Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 20
NCT03788070 Terminated Prevalence of Preoperative Dehydration in Major Elective Urologic Surgery and Its Impact on Postoperative Outcome Observational Due to COVID-19 study inclusion was halted on March 16, 2020 after 309 days. Actual 188
NCT03805711 Terminated HLT Meridian Valve CE Mark Trial N/A Interventional Sponsor decision to stop enrollment. Actual 1
NCT03814382 Terminated Acupuncture to Reduce Anxiety in Alzheimer's Disease (AD) and AD Related Dementias N/A Interventional Termination of study funding Actual 9
NCT04044378 Withdrawn Famitinib Plus Camrelizumab & Famitinib Alone & Famitinib Plus Ifosfamide in Advanced Osteosarcoma Phase 1/Phase 2 Interventional toxicity Actual 0
NCT04139694 Withdrawn Improving Insulin Resistance in Gynecological Cancer Patients N/A Interventional unable to procure supplement for clinical trial use Actual 0
NCT04393831 Suspended A Prospective Trial on Nerve Sparing Techniques Performed in Radical Prostatectomy N/A Interventional Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 112
NCT04394312 Suspended Parent PLAYSHOP: A Physical Literacy Training Workshop for Parents N/A Interventional COVID-19 physical distancing protocols and closures Anticipated 100
NCT04394832 Terminated Reducing Intrusive Memories in Refugees and Asylum Seekers With PTSD: A Pilot Study N/A Interventional Covid-19 Actual 4
NCT04277624 Suspended A Study to Assess Bioequivalence of Fezolinetant Formulations in Healthy Postmenopausal Female Participants Phase 1 Interventional Due to COVID-19. Anticipated 22
NCT01880073 Terminated FemVue and Tubal Patency N/A Interventional Slow recruitment Actual 24
NCT04394962 Suspended Virtual Reality Use in Assisted Reproductive Technology N/A Interventional Due to COVID-19 situation Anticipated 350
NCT00181220 Withdrawn Valproic Acid in the Induction of EBV Lytic Cycle Antigen Expression in Nasopharyngeal Carcinoma Phase 1 Interventional PI left JHU and is not able to be reached for updates Actual 0
NCT00358241 Withdrawn Effects of Nerve Block on Knee Function After Knee Replacement N/A Interventional PI left JHU and is not able to be reached for updates Actual 0
NCT00367718 Withdrawn Trial of VELCADE in Patients With Metastatic or Locally Recurrent Nasopharyngeal Carcinoma Phase 2 Interventional PI left JHU and is not able to be reached for updates Actual 0
NCT01493258 Withdrawn Comprehensive Informatics Framework for Comparative Effectiveness Research (CER) Dissemination N/A Interventional PI left JHU and is not able to be reached for updates Actual 0
NCT02015650 Terminated Cetuximab Compared to Mitomycin-C and 5-Fluorouracil for Locally Advanced Squamous Cell Carcinomas of the Head and Neck Phase 4 Interventional Low Recruitment rate Actual 4
NCT02232568 Terminated Trial of Feedback on Blood Use N/A Interventional Insufficient numbers of participating sites and hip surgery cases. Actual 426
NCT02536170 Suspended Arginine Therapy for Sickle Cell Disease Pain Phase 2 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 114
NCT02657356 Terminated Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST Phase 3 Interventional Exposure of these high-risk patients to clinic or in-person visits during the pandemic presented an unacceptable risk to their health Actual 202
NCT02658916 Terminated Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003 Phase 1 Interventional 251PP301(NCT03068468) primary endpoint was not met;further development of Gosuranemab BIIB092 in progressive supranuclear palsy will not be pursued. Actual 47
NCT02993354 Suspended Noninvasive Monitoring of Uterine Electrical Activity and Fetal Heart Rate: A New External Monitoring Device Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 55
NCT03054038 Suspended Afatinib and Necitumumab in Patients With EGFR Mutation Positive Advanced or Metastatic Non-small Cell Lung Cancer Phase 1 Interventional Pause for COVID-19 Response Anticipated 60
NCT03154827 Terminated A Phase Ib/II, Multicenter, Single Arm, Open-Label Study, To Evaluate the Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab Combination for Maintenance Treatment in Subjects With Acute Myeloid Leukemia Who Are 60 Years or Older - The BATTLE Study Phase 1/Phase 2 Interventional Due to lack of enrollment Actual 1
NCT03394664 Suspended FB4 (Framingham, Boston, Bloomington, Birmingham, and Baylor) N/A Interventional In light of COVID-19, the FB4 trial is indefinitely on hold. Anticipated 125
NCT03662074 Suspended Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer Phase 2 Interventional Interim analysis per protocol Anticipated 29
NCT03706872 Terminated Efficacy of an App for Monitoring Physical Activity and Weight of Obese Pregnant Women (Pas&Pes) N/A Interventional Women`s confinement for COVID-19 pandemic and changes on prenatal care. Actual 123
NCT04093349 Suspended A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE) Phase 1/Phase 2 Interventional Due to the COVID-19 pandemic, enrollment has been suspended until further notice Anticipated 20
NCT04099056 Suspended Brain Stimulation and Decision-making N/A Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 100
NCT04116606 Suspended Antidepressant Trial With P2X7 Antagonist JNJ-54175446 Phase 2 Interventional Due to currect Covid-19 pandemic. Anticipated 142
NCT04208698 Terminated A Scintigraphy Study in Adults With Diabetic Gastroparesis Phase 2 Interventional Trial was terminated due to the impact of COVID-19 on trial activities. Actual 2
NCT04261582 Suspended Genetics and Genomics of Aspirin Exacerbated Respiratory Disease (AERD) Observational On hold due to COVID-19 outbreak Anticipated 245
NCT04264637 Suspended Study to Find Out How Long it Takes Azelastine Hydrochloride 0.15% Nasal Spray to Relieve Symptoms in Patients Suffering From Allergic Rhinitis Phase 3 Interventional Covid-19 pandemic Anticipated 80
NCT03309033 Terminated Fifteen-year Immunologic Follow-up of Women Who Received One, Two and Three Doses of the Bivalent HPV Vaccine in the Costa Rica HPV-16/18 Vaccine Trial (CVT): Generating Durability Data: The ESCUDDO-CVT Study Observational NIH is not engaged in human subjects research Actual 869
NCT03204539 Terminated INdividualized ITI Based on Fviii(ATE) Protection by VWF Phase 4 Interventional Termination of funding from sponsor. Actual 1
NCT03781609 Suspended Motor Learning Approach for Manual Wheelchair Users N/A Interventional Temporarily paused due to COVID-19, expected to resume, IRB not suspended. Anticipated 48
NCT03941600 Suspended Feasibility of Exercise and Spinal Cord Injury N/A Interventional Temporarily paused due to COVID-19, expected to resume, IRB not suspended. Anticipated 40
NCT03957057 Suspended Intravenous Iron Carboxymaltose, Isomaltoside and Oral Iron Sulphate for Postpartum Anemia Phase 3 Interventional Covid-19 Anticipated 300
NCT04077879 Suspended Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP1617 in Healthy Adult Non-Asian and Japanese Subjects Including Assessment of a Food Effect Phase 1 Interventional Due to COVID-19 Anticipated 97
NCT04184895 Suspended A Study to Assess the Safety, Tolerability and Immunological Response of ASP2390 in Adult Subjects Allergic to House Dust Mites Phase 1 Interventional Due to COVID-19 Anticipated 28
NCT02479906 Terminated A Safety & Efficacy Study With Deep Transcranial Magnetic Stimulation for the Treatment of Post-Traumatic Stress Disorder (PTSD) N/A Interventional The results did not demonstrate sufficient clinical benefit induced specifically by the active treatment to justify continuation of the trial. Actual 203
NCT03032042 Withdrawn Intestinal Microbiome Post-Azythromycin/Albendazole Treatment Phase 4 Interventional We were not able to secure IRB approval in the timeline necessary to do this study. Actual 0
NCT03040024 Terminated Delirium Prevention With Ketamine in Ear, Nose, and Throat (ENT) Patients Phase 4 Interventional Halted due to COVID 19; we believe we have adequate data for analysis Actual 93
NCT03435380 Suspended Promoting Breast Cancer Screening in Women Who Survived Childhood Cancer N/A Interventional Covid-19 Anticipated 291
NCT03841357 Suspended Preventing Extension of Oligoarticular Juvenile Idiopathic Arthritis JIA (Limit-JIA) Phase 3 Interventional Covid-19 Pandemic Anticipated 306
NCT04221594 Suspended Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery Observational The study activities are suspended due to COVID Anticipated 108
NCT02642562 Suspended Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN Phase 4 Interventional COVID-19 Pandemic Anticipated 1300
NCT02890368 Terminated Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides Phase 1 Interventional Actual 56
NCT03039686 Terminated Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy Phase 2/Phase 3 Interventional A pre-planned futility analysis indicated lack of efficacy Actual 166
NCT03079882 Suspended VisR Ultrasound for Noninvasively Monitoring Renal Allograft Health Observational Suspended due to COVID-19 risks Anticipated 100
NCT03258541 Terminated Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy N/A Interventional Surgical access not facilitated- residues of hydrogel. Actual 2
NCT04391699 Withdrawn Evaluation of Prophylactic Heated Humidification on Obstructive Sleep Apnea (OSA) Patient Short Term Compliance to CPAP Therapy N/A Interventional cancelled before initiation Actual 0
NCT03277742 Withdrawn Joint Management of DM2 and Pulmonary TB in Orizaba, Veracruz N/A Interventional Due to safety reasons. The region was considered too dangerous. Actual 0
NCT03508453 Withdrawn IC14 for Treatment of Amyotrophic Lateral Sclerosis Phase 2 Interventional Study will not be conducted due to lack of funding Actual 0
NCT03617874 Suspended PC4PrEP: Integrating PrEP Into Primary Care N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 219
NCT03691376 Suspended Genetically Engineered Cells (NY-ESO-1 TCR Engineered T Cells and HSCs) After Melphalan Conditioning Regimen in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Phase 1 Interventional Temporarily Suspended due to COVID-19 Anticipated 18
NCT03937999 Suspended Bezlotoxumab as Secondary Prophylaxis for C. Difficile in High-risk Hospitalized Patients Exposed to Antibiotics. Phase 4 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval Anticipated 50
NCT04007315 Suspended SaeboGlove Therapy for Severe Upper Limb Disability and Severe Hand Impairment After Stroke N/A Interventional COVID-19 Anticipated 110
NCT04049578 Terminated A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Balovaptan in Children With Autism Spectrum Disorder Phase 1 Interventional Recent analysis of Phase II balovaptan data in paediatric ASD did not support the continuation of this study. No new safety concerns were identified. Actual 2
NCT04063709 Suspended Transcutaneous ARFI Ultrasound for Differentiating Carotid Plaque With High Stroke Risk N/A Interventional Suspended due to COVID-19 risks Anticipated 80
NCT02465034 Suspended Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 75
NCT02682082 Terminated EUS Guided Neurolysis Celiac Block w/wo Bupivacaine in Patient Being Treated Palliatively for Pancreatic Cancer N/A Interventional Closed by CHUM REB for incomplete documentation of research activities. Actual 22
NCT02685332 Suspended Phase I Dose Escalation of Single Fraction Adjuvant Stereotactic Body Partial Breast Irradiation Early Stage Breast CA Phase 1 Interventional Due to COVID-19 Anticipated 75
NCT02694965 Suspended Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma Observational COVID-19; enrollment will resume when local guidance is updated Anticipated 100
NCT02788019 Terminated Adductor Canal Mid-thigh and Adductor Canal Distal Thigh: Is Cutaneous Sensory Blockade Similar Among Block Techniques? Phase 4 Interventional Unable to complete the sample size needed for 80% power due to changes in surgical approach to adductor block usage. Anticipated 68
NCT02834754 Withdrawn Vedolizumab Post Op Study Phase 2 Interventional Limited time for enrollment of required number of subjects Actual 0
NCT02944578 Suspended Topical Curcumin for Precancer Cervical Lesions Phase 2 Interventional The study activities are on hold due to COVID-19 Anticipated 40
NCT03079297 Suspended Rapid Antidepressant Effects of Leucine Phase 2 Interventional Covid-19 Anticipated 40
NCT03353272 Suspended The Influence of a Cognitive Behavioral Approach on Changing Patient Expectations in Shoulder Pain N/A Interventional COVID-19 institutional policy Actual 33
NCT03433261 Suspended Ketogenic Diet for Reduction of CNS Oxygen Toxicity in Working Divers N/A Interventional Due to COVID-19 temporary suspension of in-person, non-essential research at Duke Anticipated 60
NCT03466398 Withdrawn Effects of a Remote Patient Monitoring Protocol on Glycemic Control in Adolescents With Type 1 Diabetes N/A Interventional Technical limitations encountered with the remote monitoring platform Actual 0
NCT03554278 Suspended Alteration of Stool Microbiota in Preterm Infants With Anemia Observational Covid-19 Anticipated 70
NCT03555981 Terminated Early Kangaroo Mother Care in Gambian Hospitalised Unstable Neonates N/A Interventional In response to COVID pandemic Actual 279
NCT03559634 Suspended Contraception Initiation Feasibility in the Pediatric ED N/A Interventional COVID Anticipated 400
NCT03599206 Suspended ONES Grant: CXCL10/CXCR3 Regulation of Ozone-Induced Epithelial Permeability Early Phase 1 Interventional COVID 19 Anticipated 100
NCT03646877 Suspended Mechanisms of Ozone-Induced Alterations in Efferocytosis and Phagocytosis Phase 1 Interventional COVID 19 Anticipated 70
NCT03647761 Suspended Does Wearing Tetra-Grip Improve Arm Function in Children Diagnosed With Neonatal Brachial Plexus Palsy? N/A Interventional Covid19 Actual 24
NCT03661645 Suspended Post-operative Methylprednisolone Taper Course for Orthopedic Surgery Phase 4 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 1000
NCT03667781 Suspended Therapeutic Drug Monitoring of Cardiac Medications Observational Covid-19 Anticipated 60
NCT03727893 Suspended Exercise Training and Manual Wheelchair Users With SCI N/A Interventional Temporarily paused due to COVID-19, expected to resume, IRB not suspended. Anticipated 30
NCT03748277 Terminated Comparison of Open and Minimally Invasive Surgical Techniques in the Treatment of Degenerative One-level Stenosis of Lumbar Spine N/A Interventional Recruitment terminated, all follow-up visits were canceled due to quarantine Actual 132
NCT03761498 Suspended Is There a Microbiome Associated With Poor Growth in Preterm Infants? Observational Covid-19 Anticipated 100
NCT03806556 Suspended A Pediatric Trial Using Tranexamic Acid in Thrombocytopenia Phase 1/Phase 2 Interventional Enrollment suspended for COVID-19 related reasons Anticipated 20
NCT03834779 Suspended HIV+ Substance Users Released From Jail N/A Interventional Covid 19 Anticipated 85
NCT03857490 Suspended Heat Therapy in Older Hypertensive Women N/A Interventional Covid-19 Anticipated 200
NCT03924245 Suspended Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers Phase 1/Phase 2 Interventional Pending site logistics Anticipated 73
NCT03976219 Suspended Measuring Evoked Potentials From the Spinal Cord and Dorsal Root Ganglion N/A Interventional Enrollment and in-person study activity suspended due to COVID-19 Anticipated 30
NCT03981835 Suspended Management of Antiplatelet Regimen During Surgical Procedures Observational [Patient Registry] Covid-19 Anticipated 1492
NCT03989635 Withdrawn Mechanistic Study of Anti-inflammatory Effects of Fevipiprant in Patients With Eosinophilic Asthma. Phase 2 Interventional Company Decision Actual 0
NCT03990740 Withdrawn Myofibroblastic Transformation Secondary to Epithelial-stromal Interactions in the Keratoconus Observational Logistical difficulties : protocol never finalized nor submitted Actual 0
NCT03999879 Suspended PhosphoRus, Proton Imaging and Amyloid BuRdEn (PREPARE) ON AMYLOID BURDEN AND COGNITION Observational Due to COVID 19 Anticipated 45
NCT04038099 Suspended Lessons on Urethral Lidocaine in Urodynamics Phase 4 Interventional Covid-19 Anticipated 70
NCT04061018 Suspended The Genetic, Protein, and Lipid Basis of Variation in Cholesterol Efflux Observational The study is temporarily suspended due to covid-19 policy. Anticipated 180
NCT04067505 Suspended Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study Phase 3 Interventional Adjustment of study protocol. Anticipated 240
NCT04106011 Suspended Cognitive Changes With Gabapentin Treatment Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 42
NCT04138953 Suspended Cortical Contributions to Motor Sequence Learning N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 60
NCT04156399 Terminated Acupuncture for Adults With Sickle Cell Disease (SCD): A Feasibility Study N/A Interventional COVID-19 pandemic Actual 6
NCT04156997 Suspended Extreme Lipids Repository Observational [Patient Registry] The study is temporarily suspended due to covid-19 policy. Anticipated 250
NCT04164732 Suspended Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy Phase 2 Interventional Only recruitment temporarily paused due to COVID-19 Anticipated 44
NCT04226833 Suspended A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function Phase 1 Interventional Recruitment is currently on hold due to COVID-19 pandemic Anticipated 24
NCT04254185 Suspended Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow N/A Interventional Enrollment and interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 378
NCT01318590 Terminated Prospective Study on Endoscopic Ultrasound (EUS) Celiac Bloc Efficacy in Chronic Pancreatitis Phase 3 Interventional Closed by CHUM REB for incomplete documentation of research activities. Actual 2
NCT04359901 Suspended Sarilumab for Patients With Moderate COVID-19 Disease Phase 2 Interventional Enrollment paused while protocol changes are pending review. Anticipated 120
NCT02026232 Suspended Metabolic Effects of Hydroxychloroquine N/A Interventional COVID-19 Anticipated 30
NCT02122666 Suspended Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome Observational COVID-19 Anticipated 100
NCT02617979 Terminated Improving Mental and Physical Health and Decreasing Hospital Readmission After Pancreatectomy Through Enhanced Patient and Caregiver Education and Engagement N/A Interventional Patients are receiving detailed packet from department and do not feel they need to go online for additional support. Actual 91
NCT03432208 Terminated A Pilot Study to Assess the Value of EUS vs EGD in Emergency Room Patients Referred for EGD N/A Interventional Closed by CHUM REB for lack of documentation related to the recruitment of participants. Actual 2
NCT03492177 Suspended A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension Phase 2 Interventional Screening on hold due to covid-19 measures Anticipated 60
NCT04392336 Suspended Tracking and Improving Trust/Respect N/A Interventional COVID-19 Anticipated 180
NCT03689244 Suspended A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or International Treatment Phase 3 Interventional Screening is temporarily halted due to COVID-19 Anticipated 280
NCT00992303 Suspended Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy Observational Due to CO-VID-19 Anticipated 10000
NCT02762604 Suspended Motor Imagery Intervention for Improving Gait and Cognition in the Elderly N/A Interventional Temporarily paused due to COVID-19. Expected to resume. Not a suspension of IRB Anticipated 48
NCT03540758 Suspended Regulation of Endogenous Glucose Production by Central KATP Channels Phase 2 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 45
NCT03566511 Suspended Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide Phase 2 Interventional Temporarily paused while we develop newer study techniques. We expect to resume; this is not a suspension of IRB approval. Anticipated 30
NCT03608163 Suspended Novel Approach for the Prevention of Hypoglycemia Associated Autonomic Failure (HAAF) Phase 4 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 45
NCT04160702 Suspended Using VR to Assess the Efficacy of a Motivational Interviewing Intervention to Increase Bystander Behaviors N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 140
NCT04384276 Suspended Weigh Easy: Simplifying Home Weight Monitoring for Infants N/A Interventional suspended due to COVID-19; no suspension of IRB Anticipated 325
NCT01201850 Terminated The Role of Bevacizumab in the Treatment of Radiation Necrosis in Children With Central Nervous System Tumors N/A Interventional Poor accrual Actual 8
NCT01486134 Terminated Major RF Ablations of Hepatomas Under MR Thermometry Monitoring N/A Interventional For technical reasons Actual 15
NCT04388371 Suspended Glutamine PET Imaging in LAM Phase 1 Interventional Due to COVID 19 Pandemic Anticipated 5
NCT01977417 Terminated Inflammation Inhibition in Prediabetic Humans Phase 2 Interventional No funding Actual 21
NCT02002507 Withdrawn Jugular Venous Flow Neurosurgical Patients Observational We faced technical problem before conducting this study Actual 0
NCT02109237 Withdrawn Sleep Disorders in Bronchiolitis Obliterans Syndrome 2&3 N/A Interventional no funding Actual 0
NCT03058068 Withdrawn Human MesenchymAl Stem Cells Infusion in Patients With Cystic Fibrosis Phase 1 Interventional PI left the institution Actual 0
NCT03066596 Suspended Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 512
NCT03122912 Suspended Explore Effects of Dietary Fish Oil in Human Skin Phase 1 Interventional Enrollment and interactions/interventions paused due to COVID-19. Expected to resume in the future. This is not a suspension of IRB approval Anticipated 46
NCT03291340 Suspended Determining the Impact of Shunting and CerebroVascular Reactivity on 7T MRI (DISCoVeR 7T MRI) Observational Recruitment temporarily suspended due to COVID-19 pandemic. Anticipated 42
NCT03128086 Terminated Weaning From Mechanical Ventilation in Neurological Patients N/A Interventional Because the principal investigator has moved to another hospital Actual 94
NCT03533400 Withdrawn Effectiveness of Jamboxx Respiratory Therapy Device: Study 1 N/A Interventional NHLBI has suggested the company focus on the other two ongoing trials Actual 0
NCT03582384 Withdrawn Use of Tocofersolan (Vedrop®) to Prevent or Treat Refractive Vitamin E Deficiency in Infants and Children Phase 2 Interventional Study never started Actual 0
NCT03361228 Terminated A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors Phase 1/Phase 2 Interventional Study was terminated early based on emerging data with epacadostat and pembrolizumab. Actual 5
NCT03722238 Suspended Actual Use and Compliance Study Of Ibuprofen 600 Mg Immediate Release/Extended Release Tablets In At-Risk OTC Consumers Phase 3 Interventional Management decision to temporarily suspend enrollment while the program is reassessed Anticipated 820
NCT03728569 Suspended Skin Barrier Dysfunction and the Role of Skin Barrier Restoration Early Phase 1 Interventional Enrollment and interactions/interventions paused due to COVID-19. Expected to resume in the future. This is not a suspension of IRB approval Anticipated 45
NCT03767491 Withdrawn Waitlist-Control Trial of Smartphone CBT for Obsessive-Compulsive Disorder (OCD) N/A Interventional Study must be registered under the sponsor instead of the site, so we have created a new posting in the sponsor's account. Actual 0
NCT03769350 Withdrawn Waitlist-Control Trial of Smartphone CBT for Major Depressive Disorder (MDD) N/A Interventional Study must be registered under the sponsor instead of the site, so we have created a new posting in the sponsor's account. Actual 0
NCT03769363 Withdrawn Waitlist-Control Trial of Smartphone CBT for Social Anxiety Disorder (SAD) N/A Interventional Study must be registered under the sponsor instead of the site, so we have created a new posting in the sponsor's account. Actual 0
NCT03861611 Suspended A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain. Phase 4 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 198
NCT04102254 Suspended Thalamic Stimulation for Epilepsy Study N/A Interventional Lead acquisition from company & COVID-19 restrictions Anticipated 15
NCT04106973 Suspended Mesothelioma Early Detection by VOCs Observational Recruitment suspended secondary to social distancing directive associated with Covid-19 Anticipated 300
NCT04203238 Suspended Potato Research for Enhancing Metabolic Outcomes N/A Interventional Due to the SARS CoV2 pandemic Anticipated 36
NCT04244682 Suspended rTMS Brain Stimulation and Cognition N/A Interventional Enrollment is suspended due to COVID-19. Anticipated 80
NCT04252417 Terminated HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects Phase 1 Interventional Due to other Phase 3 trial failure to meet primary endpoint Actual 15
NCT04252430 Terminated RI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Renal Impaired Patients and Healthy Subjects Phase 1 Interventional Due to other phase 3 trial failure to meet primary endpoint Actual 24
NCT04256148 Suspended ALXN1830 in Patients With Warm Autoimmune Hemolytic Anemia Phase 2 Interventional Study is stopped due to the COVID-19 pandemic as WAIHA patients may be at higher risk of contracting disease based on SOC treatments. Anticipated 32
NCT02824848 Terminated Perception-Action Approach vs. Passive Stretching for Infants With Congenital Muscular Torticollis N/A Interventional Study stopped due to COVID-19 pandemic and will not resume. Actual 32
NCT03055585 Terminated Applying Wolbachia to Eliminate Dengue N/A Interventional Distancing and movement restrictions of the COVID-19 emergency response made continuation of clinic-based and field entomological trial activities infeasible Actual 8173
NCT04004845 Suspended Labor Protocol Study Observational Temporarily paused due to COVID19, expected to resume. This is not a suspension of IRB approval Anticipated 740
NCT04266262 Suspended High-Intensity Training for Men With Prostate Cancer on Active Surveillance: A Feasibility Study N/A Interventional All research activities were suspended as a result of COVID-19. Anticipated 36
NCT03247231 Suspended Banding Without Resection in Small Subepithelial Tumours Observational [Patient Registry] Due to SARS-CoV2 (Covid-19) pandemia Anticipated 157
NCT03284346 Terminated Exercise in Targeting Metabolic Dysregulation in Stage I-III Breast or Prostate Cancer Survivors N/A Interventional PI left Actual 23
NCT01059513 Withdrawn Hypo-fractionated Stereotactic Body Radiotherapy for Localized Prostate Cancer Observational No participants enrolled Actual 0
NCT01605318 Withdrawn Dose Finding Study of Once or Twice Weekly IMMU-130 in Metastatic Colorectal Cancer Phase 1/Phase 2 Interventional No patients are enrolled in any studies conducted under this IND Actual 0
NCT02645487 Suspended Stereotactic Radiosurgery (SRS) for Brain Metastasis N/A Interventional Failed Audit; it was due to safety concerns after annual DSMC review, specifically safety assessments not being performed per protocol Anticipated 180
NCT02802293 Suspended Treatment of Depression With Connectivity Guided Robotically Delivered rTMS N/A Interventional Study temporarily suspended due to COVID-19 pandemic Anticipated 150
NCT03052517 Terminated Study of Safety of QAW039 in Patients With Asthma Inadequately Controlled on Standard-of-care Asthma Treatment Phase 3 Interventional Company Decision Actual 2541
NCT03171545 Suspended Enhancing the Cardiovascular Safety of Hemodialysis Care (Dialysafe) N/A Interventional Enrollment is temporarily paused due to COVID-19 and is expected to resume in the future. This is not a suspension of IRB approval. Anticipated 2100
NCT03304821 Suspended Granulocyte-Macrophage Stimulating Factor (GM-CSF) in Peripheral Arterial Disease Phase 2 Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 176
NCT03335878 Suspended Brain Health and Development With T1DM Observational Due to COVID 19. Anticipated 200
NCT03557502 Suspended Heat Therapy Versus Exercise Training in Hypertension N/A Interventional All Clinical Trials at Univ Oregon halted due to COVID-19 pandemic Anticipated 50
NCT03594994 Suspended Metabolic Effects of Sleep Extension in People With Obesity N/A Interventional Suspended due to Covid-19 Anticipated 40
NCT03646669 Suspended Symptom Perception N/A Interventional COVID-19 Anticipated 80
NCT03701828 Suspended Liver Health and Metabolic Function in People With Obesity N/A Interventional Suspended due to Covid-19 Anticipated 30
NCT03764488 Suspended A Study to Evaluate Safety, Tolerability, and Distribution of a Microdose of Radiolabeled BIIB067 (99mTc-MAG3-BIIB067) Co-administered With BIIB067 to Healthy Adults Phase 1 Interventional Healthy volunteer enrollment on hold at site due to COVID-19 pandemic. Anticipated 20
NCT04079855 Suspended Monell USDA Taste Test Study N/A Interventional corona virus Anticipated 128
NCT04259385 Suspended Effects of Sugary Drink Warning Labels on Parent Choices N/A Interventional Coronavirus stay-at-home orders prevent in-person data collection Anticipated 810
NCT04286243 Suspended Prevention of Cervical Cancer Through an HPV-based Screen-and-treat Strategy in Malawi N/A Interventional In response to COVID-19, implementation has been put on hold at sites that had already launched. Anticipated 9200
NCT02052921 Terminated Observation Versus Surgical Resection in Patients With Rectal Cancer Who Achieved Complete Clinical Response After Neoadjuvant Chemoradiotherapy N/A Interventional During the execution time foreseen in the project, the expected number of patients was not reached. Actual 13
NCT02417688 Suspended PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis Phase 1 Interventional temp suspend due to covid Anticipated 22
NCT02567110 Suspended Magnetic Resonance Spectroscopy (MRS) in Midlife Depression Observational Enrollment is temporarily suspended due to COVID-19. Anticipated 145
NCT02741648 Suspended RBC Irradiation, Anemia and Gut Injury Observational Enrollment is temporarily suspended due to COVID-19; follow up for current participants is continuing. Anticipated 220
NCT02784509 Suspended Translational Investigation of Growth and Everyday Routines in Kids Observational Temporary suspension due to COVID-19 stay-at-home order; will resume when clinic re-opens Anticipated 342
NCT02796144 Terminated MEtformin and Lorcaserin for WeighT Loss in Schizophrenia Phase 4 Interventional The FDA advised of a possible health risk associated with lorcaserin and the drug is being withdrawn. Actual 71
NCT02945644 Suspended Trazodone Dose Tolerance and APAP Adherence Phase 1 Interventional COVID19 pandemic Anticipated 45
NCT03176134 Suspended A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to <12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018) Phase 3 Interventional COVID-19 Anticipated 120
NCT03281499 Suspended Transoral Robotic Surgery and Tailored Radiotherapy in Unknown Primary and Small Squamous Cell Head and Neck Cancer N/A Interventional The study accrual is currently on hold until further notice due to the COVID-19 Pandemic. Anticipated 25
NCT03408340 Suspended Paravertebral Nerve Blocks in Neonates Phase 4 Interventional The study activities are suspended due to COVID-19 Anticipated 30
NCT03546335 Suspended Zr-89 Cimzia PET Imaging Rheumatoid Arthritis Phase 1 Interventional Lapse in study funding. Anticipated 10
NCT03660098 Suspended Mirror Box Therapy as a Treatment Option for Functional Movement Disorders Observational Due to COVID-19 virus Actual 14
NCT03840486 Suspended Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements Phase 4 Interventional Study is temporarily suspended due to COVID-19. Anticipated 116
NCT03951363 Suspended iControl Chronic Kidney Disease N/A Interventional Suspended due to COVID-19 restrictions (funding and in-person visits) Anticipated 40
NCT03975491 Suspended The Exercise And Colon Cancer Treatment Trial N/A Interventional Temporarily suspended due to COVID-19. The study is planned to re-open. Suspension does not relate to withdrawal of IRB approval. Anticipated 60
NCT04096482 Suspended Safety and Effectiveness of the Peregrine Drivable ENT Scope for Endoscopy of the Paranasal Sinuses N/A Interventional Study is temporarily on hold pending updates and supplies from the sponsor. Anticipated 30
NCT04180540 Suspended Comparison of Percutaneous Closure to Manual Compression for Hemostasis N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 130
NCT04246567 Suspended Evaluation of the Effect of Sevoflurane and Propofol Hypotensive Anesthesia on Blood Antioxidant Levels and HIF 1 Levels N/A Interventional Ethics approval is expected from the pharmaceutical institution for the study which has received the local ethics committee approval. Actual 60
NCT04278963 Suspended Yinhu Qingwen Decoction for the Treatment of Mild / Common CoVID-19 Phase 2/Phase 3 Interventional There were no eligible patients in the paticipated centers. Anticipated 300
NCT04310865 Suspended Yinhu Qingwen Granula for the Treatment of Severe CoVID-19 Phase 2/Phase 3 Interventional There were no eligible patients with CoVID-19 in the paticipated centers. Anticipated 116
NCT04382677 Suspended Families Together: Intervention for Reunified Families N/A Interventional COVID-19 social distancing restrictions--temp halt of recruitment & intervention Anticipated 255
NCT02160288 Terminated Effects of Botox in Obstructed Defecation Syndrome Phase 2 Interventional Low recruitment Actual 1
NCT03437512 Suspended Non-invasive Brain Stimulation in Adults Who Stutter N/A Interventional Covid-19 paused human subjects research at study site Anticipated 50
NCT03629964 Withdrawn Study to Develop Head Stabilizer for Use During Brain Radiation Therapy N/A Interventional PI left site. Actual 0
NCT02260141 Terminated Treating Alzheimer's and Dementia With D-ribose N/A Interventional unable to get adequate enrollment Actual 3
NCT02886936 Suspended Immediate Fit Using Innovative Technology Transtibial Prosthesis N/A Interventional COVID 19 is causing us to suspend bringing patients into the hospital for safety reasons. Anticipated 20
NCT02888587 Suspended The Innervation of Human Gut Sensory Epithelial Cells Observational COVID-19 Restrictions Anticipated 50
NCT03081026 Suspended Transphyseal Vs. Physeal Sparing ACL Reconstruction in Skeletally Immature Patients: Risk of Subsequent Lower Extremity Growth Deformity Observational COVID19 Anticipated 100
NCT03179943 Suspended Atezolizumab + Guadecitabine in Patients With Checkpoint Inhibitor Refractory or Resistant Urothelial Carcinoma Phase 2 Interventional Pending Interim Analysis Anticipated 53
NCT03303950 Terminated Busulfan, Fludarabine, Donor Stem Cell Transplant, and Cyclophosphamide in Treating Patients With Multiple Myeloma or Myelofibrosis Phase 2 Interventional Original PI left institution, new PI decided to end study Actual 6
NCT03463395 Withdrawn Efficacy of Reza Band for the Treatment of Laryngopharyngeal Reflux N/A Interventional Funding for this study has ended and we were unable to enroll any subjects Actual 0
NCT03630601 Suspended Photoacoustic Imaging in Diagnosing Changes in Tumors in Participants With Breast Cancer, Sarcoma, Skin Cancer, or Soft Tissue Malignancy and Healthy Volunteers N/A Interventional Suspended Temporarily due to COVID-19 Anticipated 90
NCT03650400 Terminated Pharmacokinetics, Safety and Tolerability of Fevipiprant Delivered Via a Once Daily Chewable Tablet in Children Aged 6 to < 12 Years With Asthma Phase 2 Interventional Company Decision Actual 12
NCT03657147 Suspended Improving African American Glaucoma Patient Involvement in Visits and Outcomes N/A Interventional Study halted prematurely due to COVID-19 but potentially will resume. Follow-up visits continue virtually. Anticipated 380
NCT03806192 Suspended Feasibility of Partners in Care Program for Caregivers of Patients With Acute Myeloid Leukemia N/A Interventional COVID19 Suspension Anticipated 40
NCT03881735 Suspended Enasidenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia With an IDH2 Gene Mutation Phase 2 Interventional Temporarily Suspended due to COVID 19 Anticipated 86
NCT03956238 Suspended Alcohol Myopia, Objectification, and Sexual Assault N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 360
NCT04032717 Suspended Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT) Phase 1 Interventional Due to the COVID-19 pandemic, study has been temporarily halted and will resume in the future Anticipated 21
NCT04037072 Suspended Efficacy of Topical Mitomycin C for Complex Benign Esophageal Anastomotic Strictures Phase 2 Interventional Due to COVID-19 Anticipated 82
NCT04048122 Suspended Feasibility and Effect of a Strategy-Based Cognitive Intervention for Parkinson Disease N/A Interventional Temporarily paused due to COVID-19 and expected to resume. Anticipated 60
NCT04199585 Terminated Safety and Tolerability of Lu AF95245 in Healthy Young Men Phase 1 Interventional new safety data from another study Actual 18
NCT04203186 Withdrawn A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI) N/A Interventional Funding was lost due to the COVID19 Pandemic Actual 0
NCT04357535 Terminated Prognosis of Coronavirus Disease 2019 (COVID-19) Patients Receiving Receiving Antihypertensives Observational We cannot meet number of subjects as recently published similar studies. Actual 17
NCT01864291 Terminated Auditory Brainstem Implant (ABI) in Pediatric Non-Neurofibromatosis Type 2 Subjects N/A Interventional Closed by IRB Actual 9
NCT04068532 Suspended A Study to Explore Pharmacodynamic Effects of BIIB104 on Brain Circuitry in Healthy Participants Phase 1 Interventional Healthy volunteer enrollment on hold at site due to COVID-19 pandemic. Anticipated 30
NCT04188301 Suspended Safety and Efficacy of IDA for Onchocerciasis Phase 2 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 201
NCT04230681 Suspended Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery Early Phase 1 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 300
NCT04246476 Suspended Sing for Your Saunter Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 60
NCT03519087 Terminated Nonarthritic Hip Disease Evaluation And Treatment N/A Interventional The planned 15-month recruitment period was completed. Actual 112
NCT04258670 Suspended Spontaneous Antigenemia in Loiasis Observational [Patient Registry] Study temporarily paused due to COVID-19 and expected to resume. Anticipated 60
NCT04258774 Suspended The Effect of Respiratory Challenge on the BOLD Signal N/A Interventional Temporarily halted due to COVID-19 Anticipated 48
NCT03637868 Withdrawn Eribulin in Brain Metastases From HER2-negative Breast Cancer Phase 2 Interventional no enrollment Actual 0
NCT03867045 Suspended Development of a Cabozantinib (Cabometyx) Symptom Management Application for Use in Patients With Renal Cancer N/A Interventional Study deemed non-essential under COVID pandemic, Anticipated 9
NCT04021914 Suspended Feasibility of EnChroma Use in the Emergency Department Setting N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 10
NCT04376736 Suspended Home Visits for Patients at Risk for Appointment No-shows N/A Interventional Covid-19 Anticipated 400
NCT02447874 Suspended Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease Phase 1/Phase 2 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 21
NCT02567448 Terminated Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA N/A Interventional Failed to accrue Actual 24
NCT02640209 Terminated Pilot Trial Of Autologous T Cells Engineered To Express Anti-CD19 Chimeric Antigen Receptor (CART19)In Combination With Ibrutinib In Patients With Relapsed Or Refractory CD19+ Chronic Lymphocytic Leukemia (CLL)Or Small Lymphocytic Lymphoma (SLL) Early Phase 1 Interventional Study is terminated due to administrative reasons. Actual 20
NCT02664337 Suspended Conjoint Analysis of Patient Preferences in Joint Interventions N/A Interventional Suspended due to COVID Anticipated 2310
NCT02918175 Suspended Mobile Health Behavioral Intervention in Patients With Heart Failure and Diabetes Mellitus N/A Interventional The study is halted due to COVID-19. Will update once enrollment resumes. Anticipated 200
NCT02978118 Suspended Exploring Relevant Immune-based Biomarkers and Circulating Tumor Cells During Treatment With Immune Checkpoint Inhibitors in Genitourinary Malignancies (CTC Immune Based Biomarkers) Observational study deemed non-essential under COVID-19 pandemic Anticipated 55
NCT03248765 Suspended Human Brain Adaptation to Chronic Pain and Its Effects on Opioid Use Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 60
NCT03253328 Suspended N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes N/A Interventional No one is currently receiving treatment and enrollment is of course on hold. Subjects being unblinded to perform interim analysis. Anticipated 50
NCT03352414 Terminated Trial Investigating Alvimopan for Enhanced Gastrointestinal Recovery After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Phase 2 Interventional stopped by sponsor Actual 58
NCT03399448 Terminated NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells) Phase 1 Interventional Sponsor has terminated trial to pursue other targets. Actual 3
NCT03577119 Suspended Full-fat Yogurt and Glucose Tolerance N/A Interventional Accrual on hold due to temporary pandemic research policy. Anticipated 32
NCT03612193 Suspended Role of the Gut Microbiome in Complex Regional Pain Syndrome Observational Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 140
NCT03670017 Suspended Glucose Time-In-Range Development Evaluation N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 50
NCT03697564 Suspended Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic Cancer Achieving Disease Control in Response to First-line Chemotherapy (GemCaN Trial). Phase 2 Interventional Working on getting accurate information for patients interested in the study. Anticipated 40
NCT03794258 Withdrawn Triple or Quadruple Combination DAAs Treatment for Subjects With HCV GT 1b Infection Phase 2 Interventional Can not recruit the patients due to the pandemic of COVID-19 Actual 0
NCT03881137 Suspended Improved Function and Quality of Life for Older Patients Receiving Radiotherapy, Part II N/A Interventional Enrolment stop 13.03.20 due to Corona pandemic. Continued suspension decided 28.04. Reopening estimated 01.10.20 Anticipated 162
NCT03926611 Suspended Dose-finding Study to Evaluate Efficacy and Safety of LOU064 in Patients With CSU Inadequately Controlled by H1-antihistamines Phase 2 Interventional COVID-19 Pandemic Anticipated 308
NCT03940651 Suspended Cardiac and Renal Biomarkers in Arthroplasty Surgery Phase 4 Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 140
NCT04006496 Suspended AML Expressive Writing N/A Interventional COVID-19 restrictions Anticipated 30
NCT04020887 Suspended Telemedicine Control Tower for the Post-Anesthesia Care Unit N/A Interventional Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 500
NCT04157179 Suspended Cerebral Oxygen Metabolism in Children N/A Interventional Temporarily halted due to COVID-19 Anticipated 350
NCT03382899 Terminated Study of Pegilodecakin (LY3500518) With Pembrolizumab Compared to Pembrolizumab Alone First-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer Phase 2 Interventional The CYPRESS-1 trial was closed early after the planned final analysis because the risk benefit ratio is unfavorable. Actual 99
NCT03382912 Terminated Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer Phase 2 Interventional The CYPRESS-2 trial was closed early after the planned final analysis because the risk benefit ratio is unfavorable. Actual 52
NCT03532490 Suspended Trial of Roflumilast in Asthma Management (TRIM) Phase 2 Interventional Suspended due to COVID-19 public health emergency. Anticipated 38
NCT03634397 Suspended Predicting Ipsilesional Motor Deficits in Stroke With Dynamic Dominance Model N/A Interventional Temporarily suspended due to Pandemic Actual 60
NCT03745781 Terminated Open-Label Placebo for Functional Dyspepsia Early Phase 1 Interventional low enrollment Actual 21
NCT03908827 Withdrawn BMAC in Severe Hip or Knee Osteoarthritis Awaiting Arthroplasty Phase 2/Phase 3 Interventional Change of study design Actual 0
NCT03938103 Suspended Evaluation of an Enhanced Delivery Model for Go NAPSACC N/A Interventional Temporarily halted as a precautionary measure due to COVID-19 pandemic. Anticipated 1189
NCT04129398 Suspended MK-8228 (Letermovir) in the Prevention of Human Cytomegalovirus (CMV) Infection and Disease in Adult Japanese Kidney Transplant Recipients (MK-8228-042) Phase 3 Interventional COVID-19 Anticipated 20
NCT04130295 Suspended Influence of Wearable Intensive Nerve Stimulation on Spasticity and Function in Persons With Spinal Cord Injury N/A Interventional Covid-19 Anticipated 12
NCT04149600 Suspended Identification of Genetic Causes of Calcific Aortic Valve Disease Observational Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 1000
NCT04203147 Suspended Home-based Diabetes-Modified Behavioral Activation Treatment for Low Income Seniors With T2DM N/A Interventional Due to COVID-19, a partial suspension of human subjects research was put into effect for research involving direct contact with human subjects. Anticipated 300
NCT04243811 Withdrawn Efficacy of Low Level Laser Therapy on İnjection Pain N/A Interventional Due to the technical problem in the laser device,it has not started. Actual 0
NCT04341870 Suspended Study of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients: Sarilumab, Azithromycin, Hydroxychloroquine Trial - CORIMUNO-19 - VIRO Phase 2/Phase 3 Interventional DSMB recommendation (futility) Actual 27
NCT03454360 Terminated CHANGE Neo™ TA Registry With ACURATE Neo™ Aortic Bioprosthesis and ACURATE Neo™ TA Transapical Delivery System Observational Sponsor business decision unrelated to product safety or efficacy. Actual 106
NCT04063241 Suspended Parent Understanding of Discharge Instructions N/A Interventional Study suspended due to Covid-19 Anticipated 778
NCT04375189 Suspended High Risk Outpatient Intern-led Care (HeROIC) Clinic Initiative N/A Interventional Covid-19 Anticipated 150
NCT00005485 Suspended The Jackson Heart Study of Cardiovascular Disease Among African Americans Observational COVID-19 outbreak Actual 5306
NCT00734838 Suspended Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy N/A Interventional COVID-19 Anticipated 205
NCT01026571 Suspended Identification of Genetic Causes of Bicuspid Aortic Valve Disease Observational Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 4000
NCT01825369 Withdrawn Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood Flow Phase 1 Interventional Changes to cardiac surgery program Actual 0
NCT01980797 Suspended International Bicuspid Aortic Valve Consortium (BAVCon) Observational [Patient Registry] Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 10000
NCT02422875 Suspended Comparative Autoantibody and Immunologic Cell Marker Study Observational [Patient Registry] Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 1050
NCT02645942 Withdrawn L-carnitine for Reducing Cardio-metabolic Risk in Patients With Obstructive Sleep Apnea N/A Interventional Study stopped due to organization reasons. Actual 0
NCT02700763 Terminated [18F]Dabrafenib Molecular Imaging in Melanoma Brain Metastasis N/A Interventional Due to the very low inlcusion rate and the current COVID-19 pandemic. Actual 1
NCT02856373 Terminated Renal Nerve Stimulation and Renal Denervation in Patients With Sympathetic Ventricular Arrhythmias Phase 2 Interventional Low enrollment number Actual 9
NCT02953431 Suspended Increased Lung Volume as Controller Therapy for Asthma Phase 1/Phase 2 Interventional COVID-19 Institution Suspension of Research Anticipated 29
NCT03001518 Suspended Immunologic Signatures Following Surgery for Pancreatic Cancer Observational COVID Anticipated 30
NCT03148288 Terminated Vitamin D Supplementation in IBS N/A Interventional low enrollment Actual 7
NCT03201549 Suspended The Effects of Increased Fructose Ingestion on FGF-21 Levels in Humans N/A Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 15
NCT02038153 Terminated Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant Phase 1/Phase 2 Interventional Low accrual Actual 3
NCT01075776 Withdrawn The Effects of C-type Natriuretic Peptide on Human Forearm Blood Vessels N/A Interventional Lack of funding Actual 0
NCT02813447 Suspended Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD) N/A Interventional COVID-19 hold Anticipated 30
NCT04316000 Suspended Anxiety and Fear of Cancer Before and After Banding Without Resection in Small SET Management (QUALI-BANDING-SET) Observational Due to SARS-CoV2 (Covid-19) pandemia and its implications for outcomes bias. Anticipated 150
NCT02277613 Terminated A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction Phase 2 Interventional Anticipated 90
NCT03456778 Suspended Achilles Tendinopathy Shear Wave Elastography Study N/A Interventional The study activities are suspended due to COVID-19 pandemic Anticipated 15
NCT02560805 Suspended Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV Phase 2 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 134
NCT03121911 Withdrawn Effects of Interval Physical Training on Expiratory Flow Limitation in Recent Myocardial Infarction N/A Interventional technical problems in equipment Actual 0
NCT03220711 Suspended Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon Phase 1 Interventional Enrollment and interactions/interventions temporarily paused due to COVID-19 & will resume in the future. No suspension of IRB approval. Anticipated 50
NCT03588715 Suspended Peg-Interferon Alpha 2b Combined With Two Intravenous Broadly HIV-1 Neutralizing Antibodies 3BNC117 and 10-1074 (BEAT-2) Phase 1 Interventional Suspended due to COVID-19 Anticipated 21
NCT03737617 Suspended Immunoglobulin Replacement Therapy for Immunoglobulin G Subclass 2 Deficient Patients With Bronchiectasis Phase 4 Interventional Cant obtain IMP Anticipated 20
NCT03858920 Suspended The Liver in the World Trade Center Health Program General Responder Cohort and Controls Observational COVID-19 Anticipated 400
NCT03927248 Withdrawn PAC-1 for Treatment of Refractory, Metastatic Kidney Cancer Phase 1/Phase 2 Interventional Withdrawn Actual 0
NCT03952858 Withdrawn Telerehabilitation in Geriatric Patients at Aarhus University Hospital, Denmark N/A Interventional Too few elible patients but only one gave informed consent Actual 0
NCT04261140 Withdrawn Clinical Evaluation of Four Aesthetic Restorations in Non-carious Cervical Lesions N/A Interventional required license Actual 0
NCT03455556 Terminated Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer Phase 1 Interventional slow accrual Actual 1
NCT01570361 Terminated Atrial Fibrillation Progression Trial Phase 4 Interventional The sponsor decided to terminate the study early due to enrolment not proceeding in accordance with expectations, independently from the study outcome. Actual 255
NCT01919489 Suspended Liraglutide Hospital Discharge Trial Phase 4 Interventional Recruitment is suspended due to COVID-19. Study visits for currently enrolled subjects are ongoing per an IRB approved amendment to reflect the pandemic status Anticipated 330
NCT02683473 Suspended Measurement of Energy Metabolism in Infants Observational Study temporarily paused due to COVID-19 and is expected to resume. This is not a suspension of IRB approval. Anticipated 40
NCT02711592 Terminated Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study N/A Interventional Lack of enrollment Actual 4
NCT02892604 Terminated Study the Feasibility of Permanent Use of inControl for the Treatment of Type 1 Diabetes N/A Interventional not enough participants Actual 3
NCT03048227 Terminated Can Continuous Glucose Measurements Help Diabetic Patients Treated With an Implantated Pump? N/A Interventional CGM Navigator isn't longer available (October 11, 2019) Actual 15
NCT03287778 Suspended Randomized Controlled Trial of Pyridoxine for Tardive Dyskinesia N/A Interventional Due to the current COVID-19 pandemic, the recruitment of new subjects is temporarily discontinued. Ongoing, randomised patients are managed per Trial Protocol. Anticipated 50
NCT03336528 Suspended A Trial Comparing Insulin Degludec and Glargine U100 for Management of Hospitalized and Discharged Patients With Type 2 Diabetes Phase 4 Interventional Recruitment is suspended due to COVID-19. Study visits for currently enrolled subjects are ongoing per an IRB approved amendment to reflect the pandemic status. Anticipated 180
NCT03338998 Suspended Efficacy, Safety and Tolerability of BAF312 Compared to Placebo in Patients With Intracerebral Hemorrhage (ICH). Phase 2 Interventional Only recruitment temporarily paused due to Covid-19. Anticipated 60
NCT03401697 Suspended Eliminating Hepatitis C Virus Observational COVID-19 Actual 52
NCT03446612 Suspended Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF) Phase 2 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 50
NCT03562767 Suspended Cognitive Behavioral Therapy for African Americans With Uncontrolled Type-2 Diabetes N/A Interventional Study activities are suspended due to COVID-19 pandemic Anticipated 45
NCT03577106 Suspended A Pilot fMRI Study of TMS in Late-Life Severe Worry N/A Interventional Due to the Covid-19 pandemic Anticipated 40
NCT03673865 Suspended The Use of 3D Printing in Orbital Fractures N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 60
NCT03704584 Suspended Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone Phase 4 Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 1000
NCT03838536 Suspended Synergistic Activity of Human Milk Nutrients and Infant Cognition N/A Interventional Suspended with COVID-9 pandemic; will resume post-pandemic. Anticipated 84
NCT03877068 Suspended Dexcom G6 Intervention Study N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 185
NCT03922581 Suspended Primary-Care Based Mindfulness Intervention N/A Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 80
NCT00793884 Suspended Emory Latino Diabetes Education Program Observational Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 3000
NCT03929562 Suspended Alcohol Screening and Pre-Operative Intervention Research Study N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 90
NCT03938350 Suspended Dialectical Behavior Therapy for Pregnant Women N/A Interventional Enrollment is temporarily suspended due to COVID-19 Anticipated 60
NCT03949244 Suspended Nailfold Capillary Blood Flow With Latanoprost Bunod Phase 4 Interventional COVID-19 Anticipated 60
NCT03958955 Suspended Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus. Phase 2 Interventional Trial put on hold due to COVID 19 pandemic. Anticipated 45
NCT03976596 Suspended Measurement of in Vivo Mitochondrial Capacity in Infants Observational Study temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. Anticipated 18
NCT04125680 Suspended English as a Second Language Health Literacy Program N/A Interventional "Enrollment is temporarily paused due to COVID-19 and is expected to reopen in the future. This is not a suspension of IRB approval." Anticipated 50
NCT04160078 Suspended Mindfulness IN-home for Diabetes and Sleep Health N/A Interventional Enrollment and study activities are temporarily suspended due to COVID-19. Anticipated 20
NCT04176497 Suspended PSMA-PET/MRI Unfavorable-Risk Target Volume Pilot Study Phase 2 Interventional Recruitment temporarily paused due to COVID-19 and expected to resume. Anticipated 42
NCT04241484 Withdrawn Piezowave for Treatment on Lateral and Medial Elbow Tendinopathies N/A Interventional PI left the institution Actual 0
NCT02492854 Suspended Standard Versus PICO Dressings in Lower-Extremity Bypass Patients N/A Interventional Currently suspended due to Covid-19 pollicies. Anticipated 40
NCT03126760 Suspended Pilot Study to Assess the Efficacy & Safety of H.P. Acthar® Gel in Subjects With Relapsing-remitting Multiple Sclerosis Phase 4 Interventional Temporarily Suspended for COVID-19 Anticipated 66
NCT03529019 Suspended Nutrition in Patient With Critical Limb Ischemia Early Phase 1 Interventional Curretly suspended due to Covid-19 policies. Anticipated 30
NCT03682497 Terminated Study in HFpEF Patients to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium Phase 1 Interventional Attendance at study sites carries risk of COVID-19 infection. Non-attendance at planned study site visits has unacceptable study related patient safety risk. Actual 68
NCT04165083 Suspended Substudy 2: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Treatment-naïve Participants With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Positive Advanced Non-small Cell Lung Cancer (NSCLC ) (MK-3475-01B/KEYNOTE-01B) Phase 2 Interventional Business Reasons Anticipated 60
NCT04371159 Suspended A Comparative, Controlled Study to Evaluate the Clinical Accuracy of the Velieve U.S. UTI Urine Analysis Test System N/A Interventional Temporarily suspended due to COVID-19 Anticipated 375
NCT04183205 Suspended Predicting SSRI Efficacy in Veterans With PTSD Phase 4 Interventional Administrative Hold on Non-Critical, In-Person Interactions with Human Research Subjects in ORD-Funded Studies due to COVID-19 Anticipated 94
NCT00807482 Suspended Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease Observational Recruitment has been suspended during COVID-19 pandemic Anticipated 1800
NCT01763359 Terminated Hip Strength and Nerve Palsy After the Modified Stoppa Approach to Acetabular Fracture Reduction and Fixation Observational The original PI moved on from this facility as did other key personnel. The current PI decided to discontinue the study. Actual 43
NCT01133678 Terminated Study in Locally Advanced Squamous Cell Carcinoma of Head and Neck Phase 2 Interventional Primary endpoint reached futility boundary Actual 50
NCT03101046 Suspended Treatment of Metastatic Castrate Resistant Prostate Cancer Patients According to Circulating Tumor Cells Kinetic Phase 2 Interventional Temporary suspension since March 2020 due to COVID-19 pandemic Anticipated 792
NCT03365921 Suspended A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial) Phase 4 Interventional Because of the epidemic of COVID-19, the serum testing could not be continued Actual 360
NCT03438552 Suspended Efficacy of Repeat Stereotactic Radiation in Patients With Intraprostatic Tumor Recurrence Phase 1/Phase 2 Interventional Temporary suspension since March 2020 due to COVID-19 pandemic Anticipated 47
NCT04224844 Suspended Erector Spinae Plane Block for Carotid Endarterectomy N/A Interventional not recruiting, awaiting for changes in IRB Anticipated 34
NCT04253795 Suspended Nonintubated Versus Intubated Anesthesia in Video-assisted Thoracic Surgery N/A Interventional not recruiting, awaiting for changes in IRB Anticipated 60
NCT04263337 Suspended NFL LONG Prospective Study Observational Enrollment temporarily suspended during COVID-19 pandemic. Anticipated 250
NCT04274465 Suspended Application of Plasma Circulating HPV DNA Testing to Management of Cervical Intraepithelial Neoplasia Observational Due to COVID-19,expected to resume. This is not a suspension of IRB approval Anticipated 85
NCT02460835 Suspended A Pilot Study of Individualized Adaptive Radiation Therapy for Hepatocellular Carcinoma N/A Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 80
NCT04372966 Terminated Uncemented Versus Cemented Total Hip Arthroplasty for Displaced Intracapsular Hip Fractures N/A Interventional The Chief Investigator (John Keating) Actual 50
NCT02887157 Suspended Analyzing Retinal Microanatomy in ROP Observational Duke University suspended non-essential in-person research on 3/13/20. Study recruitment will reopen once Duke has resumed in-person non-essential research. Anticipated 160
NCT03015831 Terminated Effect of Low Dose ColchiciNe on the InciDence of POAF Phase 3 Interventional Statistical analysis of interim data showed no advantage of colchicine Actual 254
NCT03029104 Terminated Collagen Cross-Linking With Ultraviolet-A in Asymmetric Corneas Phase 2 Interventional Sufficient clinical results obtained to support study endpoints. Actual 2228
NCT03099356 Suspended Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 19
NCT03212352 Terminated Comparing Two Medical Treatments for Early Pregnancy Failure. Phase 4 Interventional Advised by DSMB based on interim-analysis, highly significant difference. Actual 342
NCT03300505 Suspended ARRx in Combination With Enzalutamide in Metastatic Castration Resistant Prostate Cancer Phase 1/Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 35
NCT03335280 Terminated 68Ga-citrate PET/MR Imaging for Glioma Observational Low Accrual Actual 2
NCT03464851 Terminated Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis Observational Low enrollment due to inclusion/exclusion criteria Actual 51
NCT03474965 Suspended Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients Phase 2 Interventional Only recruitment temporarily paused due to COVID-19. Anticipated 100
NCT03556904 Suspended FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE) Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 72
NCT03599583 Suspended The STOP-HPV Trial 3: Prompts Intervention N/A Interventional Temporarily suspending due to the impact of COVID-19 on practices. Anticipated 48
NCT03713268 Suspended Intraoperative OCT Guidance of Intraocular Surgery II Observational Duke University suspended non-essential in-person research on 3/13/20. Study recruitment will reopen once Duke has resumed in-person non-essential research. Anticipated 262
NCT03779867 Suspended Acute Exercise Intervention in Reducing Breast Cancer Risk in Healthy Participants N/A Interventional COVID19 Suspension Anticipated 100
NCT03781778 Suspended Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors Phase 2 Interventional COVID19 Suspension Anticipated 24
NCT03785873 Suspended Phase Ib/II Trial of Nal-Irinotecan and Nivolumab as Second-Line Treatment in Patients With Advanced Biliary Tract Cancer Phase 1/Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 40
NCT03829722 Suspended Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 40
NCT03932240 Suspended In Vivo Effects of Fibrinogen Concentrate (FC) Versus Cryoprecipitate on the Neonatal Fibrin Network Structure After Cardiopulmonary Bypass (CPB) Phase 3 Interventional All subject enrollment/follow up is on hold due to COVID-19 pandemic Anticipated 36
NCT04041908 Terminated Use of a Medical Food in Adults Undergoing Surgery N/A Interventional Low enrollment Actual 1
NCT04114929 Suspended Is Threshold-based Training Superior in Cardiac Rehabilitation N/A Interventional COVID-19 Anticipated 54
NCT04158752 Suspended Anti-CGRP for Inflamation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia Phase 4 Interventional Recruitment is temporarily suspended, related to COVID-19. Anticipated 20
NCT04248907 Withdrawn Transtibial Pin Lock Suspension at Varying Distraction Values Using a Modified Air Bladder Casting System N/A Interventional Due to Corona Virus guidelines, we have decided to withdraw the study. Actual 0
NCT04283058 Withdrawn Low Dose Ketamine Infusion for the Treatment of Resistant Depression Observational Covid-19 disruption of team Actual 0
NCT03840369 Suspended Pathophysiological Understanding and Treatment of PTSD: an rTMS Approach N/A Interventional COVID-19 pandemic has halted all recruitment and pushed back the anticipated study start date. Anticipated 80
NCT03869684 Terminated A Study to Assess the Safety, Tolerability and Effectiveness of MT-0814 for the Treatment of Age-related Macular Degeneration Phase 2 Interventional The study terminated for safety reasons Actual 14
NCT03871543 Suspended Late Night Study 2: End-of-Day Assessment of Asymptomatic and Symptomatic Soft Lens Wearers N/A Interventional To ensure the safety of participants during the COVID-19 pandemic, this clinical trial is suspended until further notice Anticipated 150
NCT03952182 Suspended Effect of Bracing Versus No Bracing in Stable Thoracolumbar Compression and Burst Fractures N/A Interventional Recruitment and follow up concerns during Covid-19 pandemic Anticipated 200
NCT03965962 Suspended Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines in a Simulated Post-Exposure Regimen in Adults Phase 3 Interventional Suspended (Due to COVID-19) Anticipated 606
NCT04109768 Withdrawn Hands On Nutrition Education to Improve Childhood Health N/A Interventional PI left university Actual 0
NCT04146532 Suspended Aspirin Effects on Emotional Reactions Early Phase 1 Interventional The study was suspended due to COVID-19 cessation of research activities in March of 2020 Anticipated 200
NCT04178772 Suspended Characterizing Successful Myopic Multifocal Contact Lens Wearers N/A Interventional To ensure the safety of participants during the COVID-19 pandemic, this clinical trial is suspended until further notice Anticipated 75
NCT04205396 Suspended CAREGIVER: A Trial to Improve the Burden and Distress of Caring for Persons With Decompensated Cirrhosis N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 90
NCT02314169 Suspended Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer Phase 2 Interventional Scheduled Interim Monitoring Anticipated 137
NCT03740009 Suspended Effects of a Tissue Selective Estrogen Complex (TSEC) on Depression and the Neural Reward System in the Perimenopause" Phase 4 Interventional COVID-19 pandemic Anticipated 25
NCT04223687 Suspended Impact of Warnings on Sugar-Sweetened Beverages N/A Interventional Recruitment has been suspended due to COVID-19. Anticipated 325
NCT04302727 Suspended Delicious Eating for Life in Southern Homes N/A Interventional Recruitment has been suspended due to COVID-19. Anticipated 360
NCT03214224 Suspended Remote Pulmonary Function Testing in Amyotrophic Lateral Sclerosis N/A Interventional Restrictions on recruitment and site visits due to COVID19 Actual 49
NCT00842283 Withdrawn Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target Observational Not a clinical trial study. Actual 0
NCT02169739 Suspended Remote Preconditioning Over Time To Empower Cerebral Tissue N/A Interventional COVID 19 restrictions Anticipated 60
NCT03073460 Withdrawn The Role of Fetal Ductus Arteriosus in Predicting Spontaneous Labour at Term N/A Interventional Not able to recruit any participants Actual 0
NCT03153397 Suspended Effect of Prebiotic Fiber- Enriched (scFOS) Enteral Feeding on the Microbiome in Neurological Injury Trauma Patients (PreFEED Microbiome Trial) N/A Interventional COVID-19 Anticipated 22
NCT03318627 Withdrawn Influence of Intraoperative Repair Tension on Postoperative Healing of Full-thickness Rotator Cuff Tears N/A Interventional No capacity to conduct the study Actual 0
NCT03381183 Suspended IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma Phase 1 Interventional Currently suspended due to COVID-19 policies Actual 7
NCT03404934 Terminated Clinical Study Verifying C-REX LapAid in Clinical Practice N/A Interventional Terminated by mutual agreement between the site and sponsor Actual 13
NCT03555786 Terminated MEV for Retroclavicular Approach to Infraclavicular Block Observational Failure of recruitment Actual 45
NCT03698669 Suspended Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings N/A Interventional Recruitment suspended due to COVID-19 policies; follow up continues remotely. Anticipated 250
NCT03779516 Terminated Effect of Nebulized Lidocaine on Postoperative Sore Throat N/A Interventional change in procedure Actual 110
NCT01459666 Terminated Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer Phase 4 Interventional Investigator left institution for private practice Actual 17
NCT04368910 Terminated Safety and Efficacy of Pyronaridine Artesunate Versus Chloroquine in Children and Adult Patients With Acute Plasmodium Vivax Malaria Phase 3 Interventional Due to slow recruitment the study was terminated prematurely by the Sponsor after 30 subjects had been included Actual 30
NCT02714140 Suspended Does Preference-based HIV Testing Increase Uptake in High Risk Populations? N/A Interventional COVID-related restrictions on in-person participant contact Anticipated 1200
NCT02939222 Withdrawn Impact of Buccal Bone Thickness on Pathological Peri-implant Bone Loss: A 3-year Prospective Cohort Study N/A Interventional Actual 0
NCT03152383 Suspended Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism N/A Interventional Enrollment suspended due to COVID-19, prescreening continues for future enrollment Anticipated 100
NCT03197922 Suspended Encopresis & MIE (DoD #2) Phase 3 Interventional Enrollment suspended due to COVID-19, prescreening continues for future enrollment Anticipated 112
NCT03487822 Suspended A Personalized Self-Management Program for Older Adults With Chronic Pain and Negative Emotions N/A Interventional Temporarily paused due to COVID-19, will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 140
NCT03570892 Suspended Tisagenlecleucel in Adult Patients With Aggressive B-cell Non-Hodgkin Lymphoma Phase 3 Interventional only recruitment temporarily paused due to COVID-19 Anticipated 318
NCT03932513 Terminated Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients Phase 2 Interventional Study was halted due to suspected liver injury in another study with Inarigavir Actual 8
NCT03979638 Terminated A Dose Escalation Study of BLU-5937 in Unexplained or Refractory Chronic Cough Phase 2 Interventional Trial was terminated due to the impact of the COVID-19 on trial activities. 68 patients with refractory chronic cough were enrolled with 52 completing treatment Actual 68
NCT04026750 Terminated Insulin Tolerance Test Study in Patients With Type 1 Diabetes Phase 1 Interventional Based on scientific data collected during the trial and high screen fail rate. Actual 5
NCT04059198 Terminated Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus Phase 2 Interventional Evidence of liver injury in a separate Inarigavir study Actual 5
NCT04170374 Suspended Survey of Procedures and Resources for Initiating Treatment of HIV in Africa (South Africa) Observational Currently suspended due to COVID-19 policies Anticipated 2708
NCT04368455 Suspended Virtual Immersive Communication Training on Recommending Immunizations N/A Interventional COVID-19 Anticipated 145
NCT03870919 Suspended Locoregional Treatment and Palbociclib in de Novo, Treatment Naive, Stage IV ER+, HER2- Breast Cancer Patients N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 200
NCT03968419 Suspended This Study Will Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC. Phase 2 Interventional Only recruitment temporarily paused due to COVID-19. Anticipated 110
NCT00837395 Terminated Inflammatory Mediators and microRNA Analysis in Premenstrual Asthma Observational Co-investigator left the university and another co-investigator died several years ago, making it impossible to complete the study as planned. Actual 24
NCT03429777 Withdrawn Validation of a Smartphone-Based Hearing-in-Noise Test (HearMe) N/A Interventional Lack of novelty of study Actual 0
NCT03566303 Terminated Rivaroxaban vs Warfarin in Patients With Metallic Prosthesis Phase 2/Phase 3 Interventional Coronavirus Pandemic Actual 50
NCT03599037 Suspended Inpatient ICOUGH RECOVERY App Version 2.0 N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 50
NCT03814746 Suspended Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients Phase 3 Interventional Only recruitment temporarily paused due to COVID-19 Anticipated 240
NCT03093493 Suspended Genetics of Ehlers-Danlos Syndrome Observational [Patient Registry] Currently suspended due to Covid-19 policies. Anticipated 300
NCT03755687 Suspended Art Therapy Pain Management Adolescents Pediatric ED N/A Interventional Paused until further notice due to COVID-19 restrictions Anticipated 50
NCT03873220 Suspended Monitoring Of Scratch Via Accelerometry In Children Observational Currently suspended due to Covid-19 policies. Anticipated 50
NCT03937531 Withdrawn Void Trials After Two Voiding Trials (TVT) N/A Interventional PI Left the Institution Actual 0
NCT03953794 Withdrawn Inflammatory Bowel Disease Tracker (IBD Tracker) Observational [Patient Registry] No accrual Actual 0
NCT03962725 Suspended Avoiding Neuromuscular Blockers to Reduce Complications Phase 4 Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 100
NCT03970837 Suspended Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs) Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 1500
NCT03980483 Suspended Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing Anticipated 1500
NCT03993002 Suspended DAMP-Mediated Innate Immune Failure and Pneumonia After Trauma - the Harvard-Longwood (HALO) Campus Area Consortium N/A Interventional Enrollment has temporarily paused due to COVID-19 and is expected to resume in the future; This is not a suspension of IRB approval Anticipated 50
NCT04075396 Suspended A Study of YH25448 in Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Positive Advanced Non-Small Cell Lung Cancer (NSCLC) Phase 1/Phase 2 Interventional Recruitment temporarily on hold due to COVID-19 situation. Anticipated 30
NCT04086745 Suspended A Study of Baricitinib in Participants With Rheumatoid Arthritis Phase 4 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 1300
NCT04088409 Suspended A Study of Baricitinib (LY3009104) in Participants From 2 Years to Less Than 18 Years Old With Active JIA-Associated Uveitis or Chronic Anterior Antinuclear Antibody-Positive Uveitis Phase 3 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 40
NCT04134728 Suspended Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 525
NCT04145440 Suspended Trial to Assess Safety and Efficacy of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN) Phase 1/Phase 2 Interventional Study recruitment paused due to COVID-19 pandemic Anticipated 30
NCT04153981 Suspended A Study of Insulin Glargine (LY2963016) in Adult Participants With Type 2 Diabetes in India Phase 4 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 250
NCT04237116 Suspended A Study of Secukinumab Treatment in Patients With Plaque Psoriasis and Coexisting Non-alcoholic Fatty Liver Disease (NAFLD) Phase 3 Interventional COVID-19 Pandemic Anticipated 90
NCT02766088 Terminated This Study Will Describe the Burden of DENgue Fever Virus (DENV) Illness Among Household Members Aged 6 Months to 50 Years of Selected Communities in Latin America and Southeast Asia N/A Interventional Actual 850
NCT03053063 Terminated Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) Phase 3 Interventional This study was terminated early due to lack of efficacy based on the results of the Week 48 analysis as prespecified in the clinical study protocol. Actual 883
NCT00602329 Terminated MRI in Predicting Response in Patients Receiving Combination Chemotherapy and Bevacizumab For Advanced or Metastatic Colorectal Cancer Phase 2 Interventional Due to Poor accrual Actual 5
NCT02011971 Suspended Cognitive Effects of Vinpocetine in Healthy Adults and Patients With Epilepsy Phase 1/Phase 2 Interventional We are now considering revision of the IND to determine maximum tolerated dose Anticipated 30
NCT02174016 Suspended The Ketogenic Diet for Pediatric Acute Brain Injury N/A Interventional Funding Anticipated 5
NCT02298166 Terminated Study of Crenolanib in Combination With Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Activating FLT3 Mutations Phase 3 Interventional The manufacturer Arog Pharmaceuticals Inc has terminated the Agreement Concerning the Support of an Investigator Initiated Trial this became valid on 2020/03/09 Actual 9
NCT02302885 Suspended Healthy Human Control Blood Collection for Validation of Biomarker Assay Observational Covid-19 Anticipated 70
NCT02671084 Terminated Sevoflurane and Percutaneous Coronary Intervention by Stent Phase 4 Interventional interim analysis suggests futility Actual 701
NCT02830334 Terminated Use of the Ask Suicide-Screening Questions (ASQ) in Pediatric Outpatient Settings Observational this study was determined by IRB not to be humans subjects research Actual 525
NCT02966223 Terminated A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver N/A Interventional Sponsor prematurely withdrew financial support. Actual 20
NCT03313999 Suspended Measuring Skin Elasticity in Lymphedema Patients N/A Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 2000
NCT03321617 Suspended Glutamate Reducing Interventions in Schizophrenia Phase 1 Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 50
NCT03389620 Suspended Transforaminal Versus Lateralized Interlaminar Cervical Epidurals Phase 2 Interventional COVID-19 restrictions Anticipated 116
NCT03401931 Withdrawn Artificial Intelligence Use for the Detection of Atrial Fibrillation Drivers Observational [Patient Registry] another design of protocole is submitted for approuval before the start date Actual 0
NCT03444948 Suspended A Clinical Study of EUS-RFA (Endoscopic Ultrasound Guided Radiofrequency Ablation) for Inoperable Pancreatic Ductal Adenocarcinoma Phase 2 Interventional There was a voluntary recall from the Habib EUS RFA device manufacturer, Boston Scientific Anticipated 108
NCT03451708 Suspended OKS for the Treatment of Hemispatial Neglect N/A Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 52
NCT03472326 Terminated Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen Phase 2 Interventional GS-9131 did not meet the targeted antiviral response Actual 21
NCT03574181 Terminated Calibration Study of a Blood Alcohol Level Smart Watch Observational Extensive changes to the watch design would be needed to produce a robust device. Actual 11
NCT03579186 Suspended OKS for Gait Instability N/A Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 20
NCT03713619 Suspended This is a Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS). Phase 3 Interventional COVID-19 Pandemic Anticipated 471
NCT03713632 Suspended Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS) Phase 3 Interventional COVID-19 Pandemic Anticipated 471
NCT03715751 Suspended Adaptive Support Ventilation in Acute Respiratory Distress Syndrome N/A Interventional Enrollment has temporarily paused due to COVID-19 and is expected to resume in the future; This is not a suspension of IRB approval Anticipated 20
NCT03911063 Withdrawn Telemedicine Clinical Trial for Cognitive Behavioral Therapy in Familial Dysautonomia N/A Interventional Personnel unavailable to run the study Actual 0
NCT03915964 Suspended A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis Phase 4 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 2600
NCT03927612 Suspended Virtual Reality to Improve Social Perspective Taking N/A Interventional All study interventions have been discontinued at this time due to COVID-19, but study procedures plan to resume following the removal of COVID-19 restrictions. Anticipated 70
NCT03495713 Suspended Lymphoma RadVax LYMPHOMA: A PHASE II TRIAL OF NIVOLUMAB + LOW DOSE RADIOTHERAPY FOR INCOMPLETE RESPONDERS Phase 2 Interventional Covid-19 Anticipated 25
NCT03593395 Suspended LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study) N/A Interventional Accrual temporarily suspended during COVID-19 pandemic Anticipated 841
NCT03762109 Suspended The Use of Dantrolene to Improve Analgesia in Posterior Lumbar Surgery Phase 2 Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 100
NCT04258345 Withdrawn Artificially Sweetened Beverage Feeding Study N/A Interventional not yet funded Actual 0
NCT01280994 Suspended Hyperpolarized 129Xe MRI for Imaging Pulmonary Function Phase 1 Interventional COVID-19 Anticipated 445
NCT02014415 Suspended Alpha-1 Antitrypsin Deficiency Adult Liver Study Observational [Patient Registry] Study visits suspended due to COVID-19 pandemic. Anticipated 120
NCT04362306 Suspended Radiation Oncology Patient Medical Physics Intervention Study N/A Interventional Temporarily suspended due to pandemic Anticipated 66
NCT02478255 Suspended Longitudinal MR Imaging of Pulmonary Function in Patients Receiving Thoracic Radiation Treatment Phase 1 Interventional COVID-19 Anticipated 35
NCT02478268 Suspended Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis Phase 1 Interventional COVID-19 Anticipated 79
NCT02485366 Withdrawn Rejuvenated, Washed Packed Red Blood Cells in Pediatric Cardiac Surgery Phase 4 Interventional Product unavailability Actual 0
NCT02554383 Suspended Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit? Phase 3 Interventional In response to COVID-19. Anticipated 688
NCT02582957 Suspended Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome N/A Interventional All sites suspended because of the COVID pandemic. Anticipated 544
NCT02768727 Suspended A Test of Neural Inertia in Humans With Xenon Phase 2 Interventional Suspended due to COVID-19 Anticipated 24
NCT03143543 Terminated Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use Disorder Phase 1 Interventional FDA removal of drug from the market due to cancer risks Actual 171
NCT03182049 Withdrawn Natural History of Granulomatosis With Polyangiitis: Clinical and Genetic Biomarkers of Airway Disease NoAAC PR-03 Study Observational Funding was not able to be secured for the study and no participants enrolled. Actual 0
NCT03204916 Suspended Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic Leukemia Observational Planned evaluation of patients currently enrolled on study Anticipated 375
NCT03514511 Suspended Safety and Tolerability of LEO 138559 in Healthy Subjects and Subjects With Atopic Dermatitis Phase 1 Interventional Trial put on hold due to COVID 19 pandemic. This is a first-in-human trial and safety information about the investigational medicinal product is limited. Anticipated 54
NCT03548168 Suspended Innovative Imaging of Cerebrum and Muscle (iCAM) Repeatability Study Observational Temporarily stopped due to COVID-19 and expected to resume. Anticipated 32
NCT03571386 Suspended Mechanisms of Mindfulness-based Interventions Observational COVID-19 pandemic Anticipated 98
NCT03802630 Suspended Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion Phase 3 Interventional Only recruitment temporarily paused due to COVID-19 and safety measure Anticipated 500
NCT03810313 Suspended Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion Phase 3 Interventional Only recruitment temporarily paused due to COVID-19 and safety measure Anticipated 750
NCT03898427 Suspended Scratch Behavior Under Standard of Care Observational Currently suspended due to Covid-19 policies. Anticipated 120
NCT03973970 Suspended Assessing the Ability of the T-SPOT®.TB Test (IQ) Observational Enrollment into this study is on hold due to Covid19 Anticipated 202
NCT03978572 Suspended Dual-benefits of Aerobic and Resistance Training N/A Interventional Temporarily paused due to COVID-19 and expected to resume. Not of IRB approval Anticipated 30
NCT04005352 Suspended Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON) Phase 3 Interventional Only recruitment temporarily paused due to COVID-19 and safety measure Anticipated 692
NCT04031885 Suspended A Study of Abemaciclib (LY2835219) in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer Phase 4 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 300
NCT04046991 Suspended Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS Phase 2 Interventional Suspended due to COVID-19 Anticipated 66
NCT04047472 Suspended Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Chinese Patients With Neovascular Age-Related Macular Degeneration Phase 3 Interventional Only recruitment temporarily paused due to safety measures Anticipated 494
NCT04048668 Suspended tDCS to Treat Subacute Aphasia N/A Interventional Suspended due to COVID-19 Anticipated 30
NCT04058067 Suspended To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema Phase 3 Interventional Only recruitment temporarily paused due to safety measures Anticipated 268
NCT04117724 Suspended Antibiotic Adherence Practices in Dermatologic Surgery Observational Suspended due to COVID-19 Actual 160
NCT04127942 Withdrawn Platelet-rich Plasma Injection for Temporomandibular Disorders N/A Interventional no sufficient enrolled pateints Actual 0
NCT04141982 Suspended Clinical Concordance Evaluation of T-SPOT®.TB Assay Performance (T-Cell SelectTM Study) Observational enrollment at NECCR is on hold due to Covid 19. The other sites have completed enrollment Anticipated 700
NCT04149379 Withdrawn Hyperbaric Oxygen Therapy After Stroke - PILOT Phase 2 Interventional Because of the economic consequences of the COVID-19 pandemic 2020 Actual 0
NCT04150523 Suspended Perspectives on Prophylactic Antibiotic Use in Dermatologic Surgery Observational Suspended due to COVID-19 Anticipated 2000
NCT04159701 Suspended A Study of LY3454738 in Adults With Chronic Spontaneous Urticaria Phase 2 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 60
NCT04176653 Withdrawn Study in Beta-thalassaemia or Myelodysplastic Syndrome Patients to Investigate the Safety and Tolerability of SLN124 Phase 1 Interventional Study stopped prior to subject administered first dose, due to COVID-19 Actual 0
NCT04234724 Suspended Physiological Effects of ANGPTL3 Variants in Humans N/A Interventional Suspended due to COVID-19 Anticipated 50
NCT04269824 Suspended The Norms and Networks Sanitation Study in India in Tamil Nadu, India N/A Interventional Suspended due to COVID-19 restrictions Actual 22763
NCT02135679 Suspended The Detection Of Circulating Tumor Cells (CTC) In Patients With NSCLC Undergoing Definitive Radiotherapy Or Chemoradiotherapy Observational Covid-19 Anticipated 160
NCT04277325 Suspended Efficacy of Emotionally Focused Therapy Among Spanish Speaking Couples N/A Interventional The study has been postponed due to mobility constrains during covid-19 crisis. Anticipated 70
NCT04302831 Suspended Restoring Central Motor Control Extension N/A Interventional COVID-19 safety restrictions Anticipated 20
NCT02246738 Suspended Initial Evaluation of a Telomerase-based Circulating Tumor Cell Assay in Bladder Cancer Cohorts Observational Covid-19 Actual 87
NCT02404415 Suspended The Vanderbilt Atrial Fibrillation Ablation Registry Observational [Patient Registry] Anticipated 3000
NCT02452775 Terminated Autologous OC-L Vaccine and Ovarian Cancer Phase 1 Interventional Actual 3
NCT01736267 Terminated Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects N/A Interventional Closed by IRB Actual 3
NCT02943668 Terminated Deferasirox in Treating Patients With Very Low, Low, or Intermediate-Risk Red Blood Cell Transfusion Dependent Anemia or Myelodysplastic Syndrome Phase 2 Interventional Terminated due to low accrual Actual 2
NCT02953548 Terminated Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms (GWPCARE7) Phase 3 Interventional This study met No Go Criteria; all participants enrolled demonstrated continued hypsarrhythmia and spasms on follow-up video EEG after 2 weeks of treatment. Actual 9
NCT03151642 Suspended A PILOT STUDY OF DIFFUSION WEIGHTED MRI TO ASSESS ESOPHAGEAL TUMOR RESONSE TO NEOADJUVANT CHEMORADIATION Observational Covid-19 Anticipated 40
NCT03484923 Suspended Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma Phase 2 Interventional only recruitment temporarily paused due to COVID-19 Anticipated 230
NCT03546829 Suspended Randomized Pilot Trial of Antimicrobial Therapy and Stereotactic Body Radiation Therapy in Early-stage Non-small Cell Lung Cancer Early Phase 1 Interventional Covid-19 Anticipated 40
NCT03559049 Suspended Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer Phase 1/Phase 2 Interventional Enrollment temporarily paused for planned interim analysis; this is not a suspension of IRB approval Anticipated 55
NCT03591770 Suspended Shingrix Vaccine in Patients With Moderate to Severe Ulcerative Colitis on Tofacitinib Phase 4 Interventional Currently suspended due to Covid-19 policies. Anticipated 100
NCT03602066 Suspended Study Evaluating The Role of ClO2 on Mucositis for Pt. Undergoing Head/Neck Radiotherapy Phase 2 Interventional per Pharma company Anticipated 20
NCT03637998 Suspended Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain N/A Interventional Due to COVID-19 Anticipated 40
NCT03649659 Suspended Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions Phase 3 Interventional Enrollment and interventions are temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 1060
NCT03652909 Suspended Personal Sound Amplification Device Observational We are not seeing research patients currently due to COVID-19. Anticipated 33
NCT03688919 Suspended Adolescent Interventions to Manage Self-regulation of T1D (AIMS T1D) N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 94
NCT03791060 Suspended Secukinumab for NLD (Cosentyx) in Patients With Necrobiosis Lipoidica Diabeticorum (NLD) Phase 2 Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 18
NCT03857308 Terminated Eudaimonia and Sleep: Effects of a Mindfulness Intervention in Caregivers of People With Dementia N/A Interventional Unable to continue enrollment for dissertation study due to COVID-19 Actual 9
NCT03878459 Suspended Dapagliflozin Plus Pioglitazone in T1DM Phase 4 Interventional Temporary suspension by PI due to Covid-19 Anticipated 120
NCT03913078 Suspended Comparative Effectiveness of Social Physical Play and Traditional Exercise Programming Phase 3 Interventional Temporarily suspended due to Pandemic Anticipated 360
NCT03971149 Suspended EMPOWER Study, a Personalized Home Care Intervention for Older Heart Failure Patients N/A Interventional We came across unexpected difficulty with recruitment that has not been solved. Anticipated 25
NCT03996967 Suspended Diagnostic and Prognostic Biomarkers for Childhood Bacterial Pneumonia Observational Currently suspended due to Covid-19 policies. Anticipated 900
NCT04097834 Suspended Integrating PrEP Into Family Planning Services at Title X Clinics in the Southeastern US Observational Recruitment has been suspended due to COVID-19. Anticipated 300
NCT04175106 Suspended Evaluating the Availability of Berry Phytonutrients Post-consumption of Fresh and Processed Blueberry by Healthy Adults N/A Interventional COVID-2019 Anticipated 28
NCT04181203 Suspended Combined Apalutamide, Radiotherapy, and LHRH Agonist in Prostate Cancer Patients After Prostatectomy Phase 3 Interventional Temporary suspension since March 20 due to COVID-19 pandemic Anticipated 490
NCT04183634 Terminated An Open, Randomised, Single Dose, 2-period, 2-sequence Crossover Adhesion Study of Two Different Transdermal Patches Containing Rotigotine. Phase 1 Interventional Company Decision Actual 31
NCT04246606 Suspended Concordance of the IHC4 Score Performed in Local or Central Laboratory to Endopredict in ER+/HER2- Breast Cancer Observational Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 155
NCT04360967 Withdrawn SURF, Neurodevelopment, Growth Study in SGA Infants N/A Interventional Sponsor decision stopped in June 2017 Actual 0
NCT03197090 Terminated Handheld ECG Tracking of In-hOspital Atrial Fibrillation N/A Interventional poor patient recruitment and limited resources Actual 804
NCT01352429 Suspended Mild Hypofractionation With Proton Therapy or Intensity Modulated Radiation Therapy (IMRT) for Intermediate-Risk Prostate Cancer Observational Covid-19 Anticipated 200
NCT01952223 Suspended A Phase III of Cabazitaxel and Pelvic Radiotherapy in Localized Prostate Cancer and High-risk Features of Relapse Phase 3 Interventional Temporary suspension since March 20 due to COVID-19 pandemic Anticipated 1048
NCT02153229 Suspended Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma Phase 2 Interventional Covid-19 Anticipated 102
NCT02207465 Suspended A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer Phase 1 Interventional Covid-19 Anticipated 42
NCT02343549 Suspended A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM) Phase 2 Interventional accrual temporarily suspended during COVID-19 pandemic Anticipated 46
NCT02507011 Terminated Beta-blockers in Pulmonary Arterial Hypertension Phase 2 Interventional Recruitment Actual 4
NCT02591134 Suspended EffectS of Non-nutritive sWeetened Beverages on appetITe During aCtive weigHt Loss N/A Interventional In response to COVID-19 Anticipated 432
NCT02601833 Suspended Effectiveness of Silver Diamine Fluoride as a Treatment for Caries in Comparison to Traditional Restorative Techniques Phase 3 Interventional Intervention/interactions are temporarily paused due to COVID-19 and are expected to resume. This is not a suspension of IRB approval. Actual 98
NCT02698293 Suspended PDT Plus Vitamin D3 for Anal Dysplasia Phase 1 Interventional Covid-19 Anticipated 12
NCT02805595 Suspended Effect of Sclerotherapy on Fistulas and Sinus Tracts in Hidradenitis Suppurativa Phase 3 Interventional Enrollment and other trial activities have temporarily paused due to COVID-19 and are expected to resume in the future; This is not a suspension of IRB approval Anticipated 20
NCT02836067 Suspended Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 120
NCT02840877 Suspended The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 438
NCT02927847 Suspended Neuroimaging Reward, Behavioral Treatment, and Smoking Cessation Phase 1/Phase 2 Interventional New enrollment is temporarily suspended due to COVID19 restrictions Anticipated 100
NCT02976038 Terminated Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM) Phase 2 Interventional Registration trial did not meet the primary end points Actual 36
NCT03055884 Suspended Investigating Accelerated Learning in Healthy Subjects N/A Interventional low numbers of participants Anticipated 40
NCT03090711 Suspended Sleep as a Model to Understand and Manipulate Cortical Activity in Order to Promote Functional Recovery After Stroke N/A Interventional temporary interruption due to COVID-19 - participants belong to the risk group Anticipated 60
NCT03143842 Suspended Investigating Accelerated Learning in Tinnitus Participants Implanted With Vagus Nerve Stimulation N/A Interventional Not enough participants Anticipated 6
NCT03173794 Withdrawn CommunityRx for Hunger: A Hospital-Based Intervention N/A Interventional This trial was a duplicate entry. Recruitment was never open and no participants were enrolled. Actual 0
NCT03274440 Suspended Effects of Marijuana on Symptoms of OCD Phase 1/Phase 2 Interventional Principle Investigator was deployed to NYP to help with COVID-19 response team Actual 14
NCT03276741 Terminated Oral Intake During Labor N/A Interventional Unable to recruit to enrollment target Actual 126
NCT03301909 Suspended Development of Applications of PillCam™ Endoscopy and Patency Systems and Clinical Evaluation of Their Performance in Healthy Volunteers ("HEIGHT" Study) N/A Interventional COVID-19 Anticipated 1000
NCT03323749 Terminated A Trial to Evaluate the Safety and Efficacy of Elamipretide in Subjects With Primary Mitochondrial Myopathy Followed by an Open-Label Extension Phase 3 Interventional Part1,double blind portion of the trial did not meet the primary end points Actual 218
NCT03363711 Suspended AYA STEPS RCT: AYA Self-Management Via Texting, Education & Plans for Survivors Observational Covid-19 Actual 25
NCT03406923 Suspended Self-efficacy, Beliefs and Adherence- Pilot and Feasibility Trial of a Pharmacist-led Intervention N/A Interventional due to COVID-19 Anticipated 50
NCT03485365 Suspended A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement Study in Healthy Volunteers and Subjects With Osteoarthritis (OA) Phase 1 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 98
NCT03510988 Suspended Dedicated Breast PET/MRI in Evaluation of Extent of Disease in Women With Newly Diagnosed Breast Cancer N/A Interventional Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 147
NCT03559309 Terminated Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia Phase 4 Interventional COVID-19 Pandemic Measures Actual 24
NCT03276975 Suspended A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment Phase 2 Interventional COVID-19 restrictions Anticipated 200
NCT03653741 Suspended Effects of Perampanel on Neurophysiology Test Perimeters Phase 4 Interventional The study is temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 12
NCT03726671 Suspended Choline Nutritional Status: Development of a Biomarker Panel N/A Interventional Subject activity suspended due to COVID-19. Recruiting - respond to emails only. Anticipated 180
NCT03731598 Withdrawn Ceramides in Muscle During Insulin Resistance Observational Difficulty recruiting. Objectives from this protocol added to another protocol collecting the same information. Actual 0
NCT03790072 Suspended Ex-vivo Expanded γδ T-lymphocytes (OmnImmune®) in Patients With Acute Myeloid Leukaemia (AML) Phase 1 Interventional Suspended due to COVID-19 situation Anticipated 9
NCT03414411 Suspended Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study Observational Enrollment temporarily suspended due to covid-19 policies. Anticipated 400
NCT03994185 Withdrawn The Merit WRAPSODY™ Endovascular Stent Graft for Treatment of Iliac Artery Occlusive Disease N/A Interventional Study was withdrawn by the Sponsor prior to enrollment Actual 0
NCT04065841 Suspended Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin Compared to Each Monotherapy, in Adult Patients With NASH and Liver Fibrosis Phase 2 Interventional COVID-19 Pandemic Anticipated 210
NCT04069702 Suspended Virtual Reality for Improving Pain and Distress in Patients With Advanced Stage Colorectal Cancer N/A Interventional COVID-19 restrictions on in person activities for non-essential studies Anticipated 20
NCT03695042 Suspended Blood Flow Restriction Concussion N/A Interventional Covid-19 Anticipated 10
NCT04119024 Suspended Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma Phase 1 Interventional SAE review Anticipated 24
NCT03750643 Suspended A Study of LY3454738 in Healthy Participants and Participants With Atopic Dermatitis Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 128
NCT03764774 Suspended A Study of LY3463251 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 143
NCT03770494 Suspended A Study of LY3405105 in Participants With Advanced Cancer Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 215
NCT04214184 Suspended Biomarkers of Increased Free Living Sleep Time N/A Interventional On hold due to COVID-19 outbreak Anticipated 46
NCT03844412 Suspended Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments Phase 2 Interventional Enrollment of new participants is suspended until activities return to normal following Covid-19 resolution. Anticipated 400
NCT04273867 Suspended Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis Observational Temporarily paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 60
NCT03856359 Suspended Trial of Rifaximin in Probable Alzheimer's Disease Phase 2 Interventional Study suspended due to the Covid19 virus until further notice Anticipated 10
NCT03861923 Suspended Dry Needling for Shoulder Adhesive Capsulitis N/A Interventional Covid-19 Measures Anticipated 100
NCT03929744 Suspended A Study of LY3502970 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 160
NCT03933943 Suspended A Study of LY3361237 in Participants With Systemic Lupus Erythematosus Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 24
NCT03949842 Withdrawn Legend: TRELEGY Real World Chronic Obstructive Pulmonary Disease (COPD) Effectiveness Study Phase 4 Interventional The decision to end the study was based on a change in GSK strategy. No subjects were enrolled into the study. Actual 0
NCT03951753 Suspended A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus (T2DM) Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 117
NCT03977974 Terminated A Study of LY3526318 in Healthy Participants Phase 1 Interventional COVID-19 pandemic. Actual 76
NCT01094691 Suspended Haufen Diagnostic Biomarkers of BK Renal Disease N/A Interventional Temporary suspension of recruitment and research activities due to COVID-19 Anticipated 10
NCT04119557 Suspended A Study of LY3471851 in Participants With Psoriasis Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 40
NCT04148937 Suspended A Study of the CD73 Inhibitor LY3475070 Alone or in Combination With Pembrolizumab in Participants With Advanced Cancer Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 120
NCT02257879 Withdrawn DHB Supplement Interaction Study Observational due to constraints with collaborator and subject matter expert, recruitment was unable to begin Actual 0
NCT04152382 Suspended A Safety Study of LY3462817 in Participants With Psoriasis Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 64
NCT04165031 Suspended A Study of LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation Phase 1/Phase 2 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 230
NCT02604667 Suspended Mechanisms of Ischemic Stroke in Cancer Patients Observational Study paused due to COVID-19 and will resume based on guidance of public health authorities. This is not a suspension of IRB approval. Anticipated 165
NCT04230122 Suspended A Study of LY3478006 in Healthy Participants Phase 1 Interventional Protocol stopping criteria (safety) were met. Anticipated 56
NCT04266756 Suspended A Study of Selexipag in Healthy Male Participant Phase 1 Interventional Due to strict measures of the government to contain the spread of COVID-19 outbreak, we follow the recommendation of the Ethics Committee to suspend this trial. Anticipated 24
NCT04270370 Suspended A Study of LY3478045 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 90
NCT04329572 Suspended Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Hospitalized Patients With Moderate to Severe COVID-19 Early Phase 1 Interventional Azidus, the CRO hired for this study by Prevent Senior has lost the interest to conduct this study. Anticipated 400
NCT04348474 Suspended Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Ambulatory Patients With Mild COVID-19 Early Phase 1 Interventional Azidus, the CRO hired for this study by Prevent Senior has lost the interest to conduct this study. Anticipated 200
NCT04357704 Withdrawn Improved Speech Recognition Performance in Noise by Encoding Binaural Spatial Cues to the Cochlea Implant User N/A Interventional Delay in setting up the study. Actual 0
NCT02963766 Suspended A Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes Phase 3 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 150
NCT02115464 Terminated Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy Phase 2 Interventional The accrual rate was not high enough to reach the target sample size. Actual 54
NCT03170258 Suspended Self-activation in Individuals With and Without Nicotine Dependence N/A Interventional temporarily suspended due to COVID-19 Anticipated 100
NCT03246347 Suspended A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer Phase 2 Interventional accrual temporarily suspended during COVID-19 pandemic Anticipated 39
NCT02693743 Terminated Repetitive Transcranial Magnetic Stimulation as Treatment for Acute Suicidality in Adult Patients N/A Interventional Study terminated early due to slow accrual or other non-safety related issues Actual 1
NCT02775760 Suspended The Entorhinal Cortex and Aerobic Exercise in Aging N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 42
NCT02991456 Suspended Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide Phase 2 Interventional COVID-19 restrictions Anticipated 160
NCT03064490 Suspended Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago-gastric Diseases (PROCEED) Phase 2 Interventional COVID-19 Anticipated 38
NCT03071328 Suspended INJECT: A Pilot Study of Intra-tumoral Injections in Metastatic Urological Cancers Early Phase 1 Interventional Study deemed non-essential under COVID pandemic Anticipated 15
NCT03169075 Suspended QUALIOR Feasibility and Efficacy of a Supervised Home-based Standard Physical Exercise Program N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 312
NCT03203239 Suspended Red Light Treatment in Peripheral Artery Disease N/A Interventional COVID-19 Anticipated 40
NCT03228186 Suspended Trial of Pevonedistat Plus Docetaxel in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 37
NCT03250468 Terminated Sleep to Your Heart's Content - Insomnia Intervention for Cardiac Patients N/A Interventional Poor follow/up rates and data. Actual 52
NCT03267381 Suspended Circulating Blood Profile to Predict Recurrence and Response to Systemic Therapy Observational Pause for COVID 19 response Anticipated 30
NCT03273335 Suspended Investigating NeuroinflammaTion UnderlyIng Postoperative Brain Connectivity Changes, POCD, Delirium in Older Adults Observational COVID-19 social distancing requirements Anticipated 200
NCT03283631 Suspended Intracerebral EGFR-vIII CAR-T Cells for Recurrent GBM Phase 1 Interventional We are temporally halting enrollment until a protocol amendment is approved. Anticipated 24
NCT03297697 Suspended Minimal Residual Disease in Peripheral T-cell Lymphoma Observational COVID-19 Anticipated 42
NCT03327805 Suspended Short Term Choline and Cardiovascular Health N/A Interventional COVID-19 restrictions Anticipated 34
NCT03333356 Suspended Adjuvant Radiotherapy in Patients With Pathological High-risk Bladder Cancer (GETUG-AFU 30) N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 109
NCT03402607 Suspended Trial Comparing PLA to HIGRT Therapy (PROVE-HCC) Phase 2 Interventional COVID-19 Anticipated 90
NCT03417570 Suspended Cap Assisted Upper Endoscopy Versus High Definition White Light Endoscopy and Narrow Band Imaging Alone In The Detection Of Visible Lesions Barrett's Esophagus: A Randomized Tandem Study N/A Interventional COVID-19 Anticipated 170
NCT03423407 Suspended Evaluation of Attenuation Correction Accuracy in Positron Emission Tomography-Magnetic Resonance Imaging (PET-MRI) Observational COVID-19 Anticipated 60
NCT03436433 Suspended Seizure Prophylaxis Study Phase 2 Interventional COVID-19 restrictions Anticipated 232
NCT03516708 Suspended Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer Phase 1 Interventional COVID-19 Anticipated 39
NCT03523975 Suspended Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma Phase 1 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 28
NCT03578965 Suspended Does Antibiotic Prophylaxis Reduce Wound Complications After Vulvar Excision of Premalignant Lesions Phase 2 Interventional COVID-19 Anticipated 50
NCT03601819 Suspended Pacritinib in Relapsed/Refractory Lymphoproliferative Disorders Phase 1 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 26
NCT03617224 Withdrawn Pembrolizumab and Total Skin Electron Beam Radiotherapy in Mycosis Fungoides and Sézary Syndrome Phase 1 Interventional Unable to enroll patients that met enrollment criteria. Actual 0
NCT03617484 Suspended Bortezomib in Combination With Ibrutinib in Ibrutinib Relapsed Mantle Cell Lymphoma Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 35
NCT03687957 Suspended rhIL-7-hyFc on Increasing Lymphocyte Counts in Patients With Newly Diagnosed Non-lymphopenic Gliomas Following Radiation and Temzolomide Phase 1/Phase 2 Interventional COVID-19 Anticipated 46
NCT03697850 Suspended Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 77
NCT03707158 Suspended Kids FACE FEARS Comparative Effectiveness Research N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 1856
NCT04211350 Suspended SLEEP ON Your SIDE (SOS) Study N/A Interventional COVID-19 Anticipated 150
NCT03802396 Suspended Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction Phase 2 Interventional COVID-19 social distancing requirements Anticipated 201
NCT03809455 Withdrawn Effectiveness and Tolerance of Fentanyl Citrate in Painful Pain Induced During Diagnostic or Therapeutic Examinations in Cancer Patients Phase 2 Interventional Study was cancelled by Sponsor. Actual 0
NCT03841058 Suspended Phase II Trial of Abaloparatide vs. Placebo in Post-Menopausal Women Receiving Initial Spinal Fusion Surgery Phase 2 Interventional Due to COVID-19. Anticipated 72
NCT03851237 Suspended CCR2 PET for Pancreatic Cancer Imaging and Prediction of Response to Standard and CCR2-Targeted Therapy Phase 1 Interventional COVID-19 Anticipated 75
NCT03560960 Suspended Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease Early Phase 1 Interventional Currently suspended due to Covid-19 policies. Anticipated 240
NCT03916419 Suspended Magnetic Resonance-Guided Hypofractionated Adaptive Radiation Therapy With Concurrent Chemotherapy and Consolidation Durvalumab for Inoperable Stage IIB and IIIA Non-small Cell Lung Cancer Phase 2 Interventional COVID-19 Anticipated 27
NCT03928379 Suspended A Study of LY3305677 in Participants With Type 2 Diabetes Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 48
NCT03940742 Suspended A Study of Tirzepatide in Participants With Impaired Liver Function Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 42
NCT03964337 Suspended Immediate Prostatectomy vs. Cabozantinib Followed by Prostatectomy in Men With High-Risk Prostate Cancer Phase 2 Interventional Enrollment is suspended due to COVID-19. Anticipated 33
NCT00615784 Terminated Phase II Study of Bexarotene in Patients With Acute Myeloid Leukemia Phase 2 Interventional Study terminated. Eisai's Targretin acquired by another pharmaceutical company. Actual 25
NCT04014361 Suspended A Study of LY3154885 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 102
NCT04019054 Terminated TMS and Exposure Therapy N/A Interventional COVID Actual 17
NCT04047446 Suspended Liposomal Bupivacaine vs Dexamethasone ISB Phase 4 Interventional response to COVID-19 Anticipated 112
NCT04050553 Suspended A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 38
NCT04052594 Suspended A Study of LY3475766 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 55
NCT04081350 Suspended A Study of LY3471851 in Participants With Eczema Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 40
NCT04089865 Suspended Oral Versus IV TXA Phase 4 Interventional response to COVID-19 Anticipated 400
NCT04106206 Suspended A Safety Study of LY3372689 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 54
NCT04115007 Suspended Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients Phase 3 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 350
NCT04126161 Suspended HIP: Hip Imaging Protocol N/A Interventional COVID-19 Restrictions Anticipated 40
NCT00003645 Terminated Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence Phase 3 Interventional Per PI request Actual 64
NCT04143802 Suspended A Study of LY3437943 in Participants With Type 2 Diabetes Mellitus (T2DM) Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 75
NCT04156581 Suspended Erector Spinae Plane Block Versus Conventional Analgesia in Complex Spine Surgery Phase 4 Interventional response to COVID-19 Anticipated 46
NCT04156750 Suspended A Study of LY3556050 in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 51
NCT01409811 Terminated Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid N/A Interventional Study closed after it became too difficult to interest patients in participating. Actual 9
NCT04161976 Suspended A Study of LY900027 Given by Insulin Pump to Participants With Type 1 Diabetes Mellitus Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 20
NCT04199598 Terminated Relative Bioavailability Study With Abediterol Administered Via Three Different Inhalation Devices in Healthy Volunteers. Phase 1 Interventional The decision to terminate has been taken by the Sponsor. The decision is not due to safety concerns but reflects business prioritizations of the company. Actual 25
NCT04167072 Withdrawn Observation vs Early Removal of LAMS in EUS Guided Cholecystoenterostomy N/A Interventional Unexpected difficulties recruiting and following patients Actual 0
NCT04172987 Suspended A Study of the Effect of Tirzepatide on How the Body Handles Birth Control Pills in Healthy Female Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 42
NCT04217057 Suspended Imaging CCR2 Receptors With 64Cu-DOTA-ECL1i in Head and Neck Cancer Phase 1 Interventional COVID-19 Anticipated 20
NCT04235309 Suspended Physical Resilience: Indicators and Mechanisms in the Elderly (PRIME) Collaborative Phase 2 Observational COVID-19 social distancing requirements. Anticipated 250
NCT04259346 Suspended A Study of Two Formulations of Ixekizumab in Healthy Participants Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 216
NCT04276207 Suspended A Study of LY900014 Versus Insulin Lispro (Humalog) on High Blood Sugar in Participants With Type 1 Diabetes Who Use Insulin Pumps Phase 1 Interventional Enrollment on hold due to COVID-19 pandemic. Anticipated 28
NCT01750567 Suspended A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 40
NCT01785342 Suspended DECAMP-1: Diagnosis and Surveillance of Indeterminate Pulmonary Nodules Observational Currently suspended due to Covid-19 policies. Anticipated 500
NCT02104921 Suspended Innovative Ultrasound Technology in Neuromuscular Disease Observational COVID-19 Anticipated 240
NCT03378973 Terminated The Effects of Dexmedetomidine Dose on Motor Evoked Potentials Phase 4 Interventional No longer clinically relevant Actual 7
NCT02118805 Suspended Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders Observational COVID-19 Anticipated 200
NCT02300194 Withdrawn Randomized, Double-blind, Placebo, Controlled Cross Over Design Topical Morphine for Analgesia in Pediatric Procedures Phase 4 Interventional Withdrawn by investigators Actual 0
NCT02504697 Suspended DECAMP-2: Screening of Patients With Early Stage Lung Cancer or at High Risk for Developing Lung Cancer Observational Currently suspended due to Covid-19 policies. Anticipated 800
NCT02613598 Suspended Dose Escalation Study to Determine the Maximum Tolerated Dose of the Combination of Ruxolitinib and Bortezomib in Patients With Relapsed or Refractory Lymphoma Phase 1 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 24
NCT02667119 Suspended Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults N/A Interventional due to COVID-19 Anticipated 40
NCT02718391 Terminated Complementary Vaccination With Dendritic Cells Pulsed With Autologous Tumor Lysate in Resected Stage III and IV Melanoma Patients. Phase 2 Interventional The randomization to the observational arm of the trial was no longer ethical Actual 12
NCT02718404 Terminated 3 Tesla Magnetic Resonance Guided High Intensity Focused Ultrasound in the Treatment of Pain From Bone Metastases of Solid Tumors N/A Interventional following the non-renewal of the loan agreement for the medical device Actual 12
NCT02781792 Suspended Temozolomide Chronotherapy for High Grade Glioma Phase 2 Interventional COVID-19 Anticipated 40
NCT02817958 Suspended Evaluation of Lymphadenectomy and Chemotherapy TIP on Inguinal Lymph Nodes in Squamous Cell Carcinoma of the Penis (AFU-GETUG 25) Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 37
NCT02891759 Suspended Compare Outcomes Between Two Acellular Dermal Matrices Phase 2 Interventional COVID-19 Anticipated 400
NCT00300638 Suspended Alcoholism: Emotion and Thinking Observational Currently suspended due to COVID-19 policies. Anticipated 700
NCT02521558 Suspended Effectiveness of Home-based Electronic Cognitive Therapy in Alzheimer's Disease N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 100
NCT02918435 Suspended Implementing an Intervention to Address Social Determinants of Health in Pediatric Practices N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 2520
NCT03062111 Suspended Laser Enucleation of Prostate (LEP) Versus Transurethral Resection of Prostate (TURP) N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 100
NCT03462940 Suspended Effects of TUDCA on Endothelial Function in Type 2 DM N/A Interventional Currently suspended due to covid-19 policies. Anticipated 25
NCT03637296 Suspended Adapting Critical Time Intervention to Support Inpatient Medical Care Transition N/A Interventional This study is temporarily suspended due to COVID-19 pandemic Anticipated 60
NCT03644927 Suspended Exercise Maintenance in Chronic Pain and PTSD N/A Interventional Currently suspended due to Covid-19 policies. Anticipated 70
NCT03929640 Suspended Management Of Pain After Cesarean Trial Phase 3 Interventional Temporarily suspended due to Pandemic Anticipated 144
NCT04247061 Suspended Usability Study of a Smoking Cessation Intervention During a Dental Cleaning N/A Interventional Currently suspended due to COVID-19 policies. Anticipated 15
NCT03430531 Suspended Effectiveness of Sphenopalatine Ganglion Block for Post-Dural Puncture Headache Phase 2 Interventional Temporarily suspended due to Pandemic Anticipated 30
NCT03507374 Terminated PCSK9 Inhibition in Patients With Symptomatic Intracranial Atherosclerosis Early Phase 1 Interventional Funding withdrawn Actual 20
NCT03576976 Suspended Improving Accessibility and Personalization of CR for Schizophrenia N/A Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 100
NCT03637842 Suspended Lorcaserin for Cannabis Use Disorder Early Phase 1 Interventional suspended due to lorcaserin recall Anticipated 90
NCT03711500 Suspended D-serine Augmentation of Neuroplasticity Phase 1/Phase 2 Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 45
NCT03739840 Suspended A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 500
NCT03740139 Suspended The Police-Mental Health Linkage System N/A Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 1600
NCT03817528 Suspended ITI-007 (Lumateperone Tosylate) for Schizophrenia Phase 2 Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 40
NCT03895203 Suspended A Study to Test the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 840
NCT03896581 Suspended A Study to Evaluate the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 390
NCT03928743 Suspended A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 300
NCT03971422 Suspended A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 240
NCT04039919 Suspended A Study to Test the Pharmacodynamic, Pharmacokinetic, Safety, and Tolerability of Padsevonil in Healthy Study Participants Receiving Either Ethanol or Cannabidiol Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 44
NCT04200456 Suspended A Study to Evaluate the Efficacy, Safety, and Tolerability of Rozanolixizumab in Adult Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP) Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 105
NCT04242446 Suspended A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 490
NCT04242498 Suspended A Study to Test the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 490
NCT04283136 Suspended A Study to Test the Blood Concentration of 4 Padsevonil Product Variants and the Effect of Food on Padsevonil Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 46
NCT04335578 Suspended A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of UCB7858 in Adult Kidney Transplant Recipients With Chronic Allograft Injury Phase 1/Phase 2 Interventional Study recruitment temporarily halted as a precautionary measure due to COVID-19 pandemic Actual 1
NCT01376752 Suspended Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) in Relapse Ovarian Cancer Treatment Phase 3 Interventional Temporary suspension since March 20th 2020 due to COVID-19 pandemic Anticipated 444
NCT01829386 Suspended Non-Heme Iron Load Quantification in the Brain - MRI of Patients With Stroke Observational Enrollment is temporarily paused due to COVID-19 and are expected to resume in the future. This is not a suspension of IRB approval. Anticipated 10
NCT01905397 Suspended Negative Pressure Wound Therapy to Reduce Surgical Site Infection N/A Interventional COVID-19 - Pending approval to re-open study and add additional subjects Anticipated 135
NCT02229565 Suspended Molecular Mechanisms Underlying Prostate Cancer Disparities N/A Interventional Study deemed non-essential under COVID pandemic. Anticipated 198
NCT02553525 Suspended Effects of Stimulation Patterns of Deep Brain Stimulation N/A Interventional temporarily suspended due to COVID-19 social distancing measures Anticipated 180
NCT02834065 Suspended Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest N/A Interventional Enrollment suspended during the COVID-19 pandemic Anticipated 273
NCT02933671 Suspended Suprainguinal Fascia Iliaca (SIFI) Block Improves Analgesia Following Total Hip Arthroplasty Phase 4 Interventional COVID -19 HOLD Anticipated 40
NCT02967289 Suspended IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting Phase 3 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 640
NCT02980510 Suspended Comparison FOLFIRINOX Panitumumab vs mFOLFOX6 Panitumumab in RAS/B-RAF Wild-type Metastatic Colorectal Cancer Patients Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 209
NCT03025087 Suspended Hydroxychloroquine and Cognitive Function After Surgery Phase 4 Interventional Recruitment suspending during the COVID-19 pandemic. Anticipated 30
NCT03081052 Suspended Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes Phase 4 Interventional Enrollment suspended during the COVID-19 pandemic Anticipated 424
NCT03164655 Suspended Improving SUrgery of Liver Metastases: a Trial of the Arterial Chemotherapy Network Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 140
NCT03268304 Withdrawn Feasibility of Two New Software Modules for the Rehabilitation of Patients With Neuromuscular Upper Limb Impairments Observational The software modules were not completed. Actual 0
NCT03353233 Suspended Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty. Phase 4 Interventional COVID-19 HOLD Anticipated 38
NCT03371173 Terminated ORal IrON Supplementation With Ferric Maltol in Patients With Pulmonary Hypertension (ORION-PH-1) Phase 3 Interventional low recruitment rate; difficulties to achieve planned number of participants within reasonable time frame Actual 22
NCT03403465 Suspended Intratreatment FDG-PET During Radiation Therapy for Gynecologic and Gastrointestinal Cancers Phase 2 Interventional COVID-19 restrictions Anticipated 130
NCT03513302 Suspended Dietary Nitrate and Muscle Power With Aging Phase 1 Interventional COVID-19 pandemic Anticipated 20
NCT03533985 Suspended Effect of Music Therapy on Infants With Neonatal Abstinence Syndrome N/A Interventional COVID-19 Anticipated 200
NCT03595774 Suspended Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals Phase 1 Interventional COVID-19 pandemic Anticipated 10
NCT03628560 Suspended Alternate Methodology of Pulse Oximeter Validation N/A Interventional COVID-19 HOLD Anticipated 30
NCT03695172 Suspended Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section Phase 4 Interventional Suspended due to COVID-19 Anticipated 75
NCT03928704 Suspended A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Nonradiographic Axial Spondyloarthritis Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 240
NCT03726268 Suspended Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement) Phase 4 Interventional COVID-19 HOLD Anticipated 1000
NCT03774615 Terminated ORal IrON Supplementation With Ferric Maltol in Patients With Heart Failure Carrying Left Ventricular Assist Devices Phase 4 Interventional low recruitment rate; difficulties to achieve planned number of participants within reasonable time frame Actual 11
NCT03777813 Suspended Association of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 120
NCT03807518 Suspended Pre- and Post-Operative Exercise Program in Upper Gastrointestinal Cancers N/A Interventional Suspended due to COVID-19 Anticipated 64
NCT03815656 Suspended Closed Loop DBS Implanted RC+S Study N/A Interventional temporarily suspended due to COVID-19 social distancing measures Anticipated 6
NCT03827291 Suspended QL Block With Exparel in Colectomy Phase 4 Interventional COVID-19 Hold Anticipated 30
NCT03839082 Suspended Structured Mobile Technology Based Lifestyle Program vs Usual Care for Patients With Non-alcoholic Fatty Liver Disease N/A Interventional Enrollment and interactions/interventions are temporarily paused due to COVID-19 and are expected to resume. This is not a suspension of IRB approval. Anticipated 120
NCT03863639 Suspended Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia Observational Enrollment hold Anticipated 30
NCT03928808 Suspended Fecal Microbiota Transplantation (FMT) in Treatment of Severe and Enduring Anorexia Nervosa Early Phase 1 Interventional Currently on partial clinical hold due to COVID-19 policies. Anticipated 10
NCT03943667 Suspended Gemcitabine and Paclitaxel vs Gemcitabine Alone After FOLFIRINOX Failure in Metastatic Pancreatic Ductal Adenocarcinoma Phase 3 Interventional Temporary suspension since March 20th, 2020 due to COVID-19 pandemic Anticipated 210
NCT03958552 Suspended Palliative Care Consultations in the Skilled Nursing Facility (SNF) Setting N/A Interventional Suspended do to COVID-19 Anticipated 160
NCT03962348 Suspended Reducing DUP Through Early Detection in a Large Jail System N/A Interventional This study is temporarily suspended due to COVID-19 pandemic. Anticipated 20
NCT03995238 Suspended Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation N/A Interventional Temporarily supended due to COVID-19 Anticipated 54
NCT04095442 Suspended Effect of Antibacterial Mouthwash on Muscle Function in Healthy Young Men and Women Early Phase 1 Interventional COVID-19 pandemic Anticipated 16
NCT04136444 Suspended A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 24
NCT04158362 Suspended Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer Phase 3 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 378
NCT04163016 Suspended A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 20
NCT04255862 Suspended A Study to Evaluate the Bioequivalence of Bimekizumab Given as 1x2mL or 2x1mL Subcutaneous Injection in Healthy Study Participants Phase 1 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 400
NCT04270045 Suspended Forced Oscillometry in Infants With Bronchopulmonary Dysplasia Observational Suspended per institutional directive due to COVID-19 Pandemic; No suspension of IRB approval Anticipated 20
NCT04278872 Suspended Phase 2 Study of SJX-653 in Postmenopausal Women With Moderate to Severe Vasomotor Symptoms Phase 2 Interventional Temporarily halted due to COVID-19 Anticipated 130
NCT01803906 Suspended Tissue Sample Study for Mitochondrial Disorders Observational Recruitment on hold Anticipated 6900
NCT01913327 Terminated Antipsychotic Effects on Brain Function in Schizophrenia Phase 4 Interventional Insufficient Funds and Inadequate Subject Recruitment Actual 4
NCT02316574 Suspended The Role of Neural Systems for Emotion Regulation in Coping With Alcohol Craving N/A Interventional This study is temporarily suspended due to COVID-19 pandemic Anticipated 40
NCT03405714 Suspended A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Intravenous Brivaracetam in Subjects >= 1 Month to < 16 Years of Age With Epilepsy Phase 2 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic. Anticipated 50
NCT03457077 Suspended Neural and Mobile Assessment OF Behavior Change Among Problem Drinkers N/A Interventional This study is temporarily suspended due to COVID-19 pandemic Anticipated 150
NCT03496792 Suspended The Venous Distension Reflex and Orthostatic Hypertension N/A Interventional Temporarily suspended due to Pandemic Anticipated 30
NCT03513770 Suspended Autonomic Control of the Circulation and VDR Early Phase 1 Interventional Temporarily suspended due to Pandemic Anticipated 18
NCT03518606 Suspended Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours Phase 1/Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 150
NCT03612960 Suspended Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes Early Phase 1 Interventional Temporarily suspended due to Pandemic Anticipated 90
NCT03649477 Suspended Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome Phase 3 Interventional Enrollment is paused due to COVID-19. This is not a suspension of IRB approval. Anticipated 175
NCT03761030 Suspended L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults Phase 4 Interventional This study is temporarily suspended due to COVID-19 pandemic. Actual 30
NCT03774732 Suspended PD-(L)1 Inhibitors With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer Phase 3 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 510
NCT03812588 Suspended Contact: Developing New Clinical Management Strategies Phase 4 Interventional This study is temporarily suspended due to COVID-19 pandemic. Actual 29
NCT03812614 Suspended Comparative Effectiveness of Family vs. Individually Focused Diabetes Education and Support N/A Interventional Study recruitment is temporarily suspended to maximize the safety of participants and staff due to current concerns about transmission of COVID-19. Anticipated 536
NCT03861481 Suspended A Study to Assess the Efficacy, Safety and Tolerability of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy Phase 2 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 34
NCT03878342 Suspended Radiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 666
NCT03887078 Suspended Noom Coach for Bariatric Health N/A Interventional Covid-19 Anticipated 200
NCT03905928 Suspended Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes N/A Interventional Temporarily suspended due to Pandemic Anticipated 56
NCT03910673 Suspended Intravenous Fosfomycin Pharmacokinetics Study Phase 1 Interventional COVID-19 Anticipated 33
NCT03957525 Terminated Pediatric Preoperative Virtual Reality Program N/A Interventional Recruiting process could not be completed; lack of participants Actual 11
NCT04026776 Suspended Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm Early Phase 1 Interventional COVID19 Anticipated 210
NCT03306849 Suspended Ultrasonographic Evaluation of Anovulatory Disorders in Lean and Overweight Women Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 150
NCT04035200 Suspended Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation Phase 2 Interventional Study recruitment suspended during COVID-19 pandemic Anticipated 150
NCT04044716 Suspended Nurse Initiated Acupressure for Pain Management N/A Interventional COVID 19 Anticipated 52
NCT04051229 Suspended Exercise Training and Metabolic Flexibility in Prediabetes N/A Interventional COVID 19 Anticipated 20
NCT04083053 Suspended High-Resolution Anoscopy Perceived Discomfort Study N/A Interventional COVID 19 Anticipated 54
NCT04084093 Withdrawn Evaluating the Use of a Concentrated Surfactant Gel in Burn Patients N/A Interventional Study will be redesigned. Actual 0
NCT04097717 Suspended My Decision Tubal Sterilization Decision Support Tool N/A Interventional This study has been temporarily suspended due to the COVID-19 pandemic. Anticipated 350
NCT04124939 Suspended Is 10 Injections of Bladder Botox Less Painful Than 20 Injections? Phase 4 Interventional COVID19 Anticipated 40
NCT04126343 Suspended A Study to Test the Cardiac Effects of Padsevonil in Healthy Study Participants Phase 1 Interventional Study temporarily halted as a precautionary measure due to the COVID-19 pandemic Actual 45
NCT04132960 Suspended Study of DS-8201a, an Antibody Drug Conjugate for Advanced Breast Cancer Patients, With Biomarkers Analysis Phase 2 Interventional Temporary suspension since March 19 due to COVID-19 pandemic Anticipated 162
NCT03539835 Suspended Resistance Training to Improve Fatigue and Physical Function in Postmenopausal Breast Cancer Survivors N/A Interventional Study suspended temporarily due to COVID-19 Anticipated 50
NCT04159571 Suspended QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt N/A Interventional COVID 19 Anticipated 138
NCT03547453 Suspended Ovarian Ultrasonography for the Clinical Evaluation of Polycystic Ovary Syndrome Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 240
NCT04180709 Suspended CBT to Reduce Insomnia and Improve Social Recovery in Early Psychosis N/A Interventional All non-COVID-19 NIHR research is suspended due to social distancing measures. Anticipated 44
NCT04302389 Suspended Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program N/A Interventional due to COVID-19 Anticipated 150
NCT03621670 Suspended GlaxoSmithKline's (GSK) Safety and Immunogenicity Study of GSK Meningococcal Group B and 13-valent Pneumococcal Vaccines Administered Together With Routine Infant Vaccines in Healthy Infants Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 1800
NCT04353258 Suspended Research Intervention to Support Healthy Eating and Exercise N/A Interventional due to COVID-19 Anticipated 192
NCT03756285 Suspended Safety and Tolerability Study of AZD4831 in Patients With Heart Failure. Phase 2 Interventional Study put on hold due to Covid-19 situation and for the safety of our study subjects. Anticipated 96
NCT03795350 Terminated Lung Deposition of TRIMBOW® pMDI in Healthy Volunteers, Asthmatic and COPD Patients Phase 1 Interventional In light of the cessation of non-essential clinical activities at CPU due to the COVID-19 pandemic, the sponsor has determined to terminate the study early. Actual 19
NCT04273321 Suspended Efficacy and Safety of Corticosteroids in COVID-19 N/A Interventional The epidemic of COVID-19 in China has been coming to an end. Anticipated 400
NCT00930046 Terminated The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine N/A Interventional The institution transitioned from open surgical procedure to Robotic procedure Actual 15
NCT01785719 Suspended Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss N/A Interventional Suspended due to COVID-19; no suspension of IRB approval. Anticipated 100
NCT01859663 Suspended Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 360
NCT01927432 Suspended Ultrasound Characterization of Ovarian Follicle Dynamics in Women With Amenorrhea Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 80
NCT01927471 Suspended Nutritional and Metabolic Correlates of Ovarian Morphology in Women With Polycystic Ovary Syndrome Observational Suspended due to COVID-19; no suspension of IRB approval. Anticipated 360
NCT02753283 Suspended Preventing Osteoporosis Using Denosumab Phase 4 Interventional IRB recruitment suspension due to COVID-19 related research restrictions. Anticipated 212
NCT03037580 Terminated Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction Phase 3 Interventional Terminated by sponsor Actual 84
NCT03043651 Terminated Study of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Heart Failure With Preserved Ejection Fraction (HFpEF) Phase 3 Interventional Terminated by sponsor Actual 48
NCT03077776 Suspended Tracking Triple-negative Breast Cancer Evolution Through Therapy N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 250
NCT03143322 Suspended Standard Treatment +/- SBRT in Solid Tumors Patients With Between 1 and 3 Bone-only Metastases N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 196
NCT03279952 Suspended Neurophysiological Markers of Pediatric Irritability and Its Response to Intervention Phase 4 Interventional Temporarily suspended due to Pandemic Anticipated 47
NCT03288389 Suspended Membrane Lipid Replacement in Fibromyalgia N/A Interventional until further notice due to COVID-19 pandemic. Anticipated 60
NCT03297762 Terminated Increasing Use of Continuous Glucose Monitors in Publicly-insured Youth With Type 1 Diabetes N/A Interventional Enrollment challenges Actual 4
NCT03321006 Suspended Treating Hearing Loss to Improve Mood and Cognition in Older Adults Phase 4 Interventional This study is temporarily suspended due to COVID-19 pandemic. Actual 27
NCT03338257 Suspended Husky Reads Effectiveness in Increasing Produce Preference and Food Group Identification in Preschool Children N/A Interventional Covid 19 pandemic Anticipated 900
NCT03381859 Withdrawn Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4 Phase 4 Interventional HCV treatment expansion occurred in Egypt Actual 0
NCT03386006 Suspended Noom Coach for Bariatric Surgery N/A Interventional COVID-19 Anticipated 50
NCT03386162 Suspended SAFIR PI3K A Phase II Randomized Trial Comparing Alpelisib and Fulvestrant Versus Chemotherapy as Maintenance Therapy in Patients With PIK3CA Mutated Advanced Breast Cancer Phase 2 Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 90
NCT03460548 Terminated REMOGEN® Omega Versus Cationorm® in the Treatment of Patients Suffering From Dry Eye N/A Interventional low recruitment rate Actual 26
NCT02880241 Suspended MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria Phase 2 Interventional Precautionary delay in response to the COVID-19 pandemic. Anticipated 102
NCT03080168 Suspended The "AIM Study": Investigating Whether Actigraphy and Ideation Measures Can Promote Patient Safety Observational Due to Covid-19 Anticipated 175
NCT03225092 Withdrawn Platelet-rich Plasma Injections for Persistent Medial Knee Pain After Total Knee Arthroplasty Early Phase 1 Interventional Unable to recruit enough study participants Actual 0
NCT03287947 Suspended LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal Carcinoma Phase 2 Interventional Low enrollment Actual 5
NCT03325439 Suspended A Study to Test the Pharmacokinetics, Efficacy, and Safety of Brivaracetam in Newborns With Repeated Electroencephalographic Seizures Phase 2/Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 42
NCT03557281 Suspended An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis Phase 2 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 80
NCT03582514 Withdrawn Dose and Volume Escalation of Preoperative Brain Irradiation in GBM Patients -the POBIG Trial - N/A Interventional The participating site went broke and no new participating sites have been found Actual 0
NCT03682848 Suspended Safety and Efficacy of Dolutegravir/Lamivudine (DTG/3TC) in Therapy-naive Human Immunodeficiency Virus-1 (HIV-1) Infected Adolescents Phase 3 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 30
NCT03709992 Suspended Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms: N/A Interventional Because of COVID-19 Crisis Anticipated 200
NCT03729401 Suspended Personalization of Long-Term Antiplatelet Therapy - RAPID EXTEND Phase 4 Interventional COVID-19 pandemic Anticipated 390
NCT03810118 Suspended Fluid Challenge Infusion and Response N/A Interventional COVID-19 outbreak and elective surgery stopped Anticipated 98
NCT03844282 Suspended Research Evaluating Sports ConcUssion Events - Rapid Assessment of Concussion and Evidence for Return Observational Coronavirus pandemic - University facilities closed Anticipated 120
NCT03900832 Suspended Effects of Heating on Exercise Pressor Reflex in Peripheral Artery Disease: Exercise Ability Early Phase 1 Interventional Temporarily suspended due to Pandemic. Anticipated 32
NCT03903380 Terminated Manual Therapy and Exercise With Mixed Reality With Hololens® Exercise Protocol in Chronic Neck Pain Patiens. N/A Interventional problems recruiting the sample; derived from pandemic situation COVID-19 Actual 14
NCT04021472 Suspended Evaluate Health Coaching Support in Technology-based Interventions for Meeting Health Goals N/A Interventional Trial is suspended due to COVID-19. Anticipated 40
NCT04039191 Suspended SMS Education for Post-operative Pain N/A Interventional COVID 19 Anticipated 250
NCT04059822 Suspended Slow and Deep Breathing to Lower Blood Pressure in Women With Pregnancy-induced Hypertension N/A Interventional Recruitment on hold - COVID-19 Anticipated 67
NCT04123795 Suspended A Study to Evaluate the Efficacy, Safety, and Drug Concentration of Certolizumab Pegol (CZP) in Children and Adolescent Study Participants With Moderate to Severe Chronic Plaque Psoriasis (PSO) Phase 3 Interventional Study recruitment temporarily halted as a precautionary measure due to the COVID-19 pandemic Anticipated 150
NCT04167748 Withdrawn Preimplantation Genetic Testing for Aneuploidy (PGT-A) in Women Over 36 Years of Age N/A Interventional Per discretion of principal investigator Actual 0
NCT04167852 Suspended Mindfulness Meditation and Bariatric Surgery N/A Interventional COVID 19 Anticipated 189
NCT04185428 Suspended Investigating Integrative Therapies for Symptom Management in Adults With Acute Myeloid Leukemia N/A Interventional Due to COVID-19 Anticipated 60
NCT04195958 Suspended A Study to Assess the Impact of Omalizumab on Exercise Capacity, Physical Activity, and Sleep Quality in Participants With Moderate to Severe Allergic Asthma Phase 4 Interventional Due to the COVID-19 pandemic, recruitment and screening visits have been suspended until further notice. Anticipated 150
NCT04299282 Suspended CIED Implantation in Low BMI Patients N/A Interventional Postponed due to COVID-19 pandemic Anticipated 20
NCT02658656 Suspended Powered Exoskeletons in Persons With SCI N/A Interventional Administrative hold due to COVID-19 pandemic Anticipated 160
NCT03152084 Terminated The Study Will Evaluate Average 24-hr Sodium Excretion During Dapagliflozin Treatment in Patients With Type 2 Diabetes Mellitus With Preserved or Impaired Renal Function or Non-diabetics With Impaired Renal Function. Phase 4 Interventional Poor recruitment. Actual 25
NCT03229941 Suspended Transfusion Trigger After Operations in High Cardiac Risk Patients N/A Interventional As a consequnce of COVID 19 and after consultation with research oversight, regulatory and monitoring entities enrollment has been placed on a temporary hold. Anticipated 3070
NCT03281044 Terminated Fecal Microbiota Transplantation in Depression Phase 2 Interventional Although not observed in our patients (4 enrolled), SAEs have been reported in other patients receiving the same product. Actual 4
NCT03335059 Terminated Mitomycin C Intravesical Chemotherapy in Conjunction With Synergo® Radiofrequency-Induced Hyperthermia for Treatment of Carcinoma in Situ Non-Muscle Invasive Bladder Cancer Patients Unresponsive to Bacillus Calmette-Guérin, With or Without Papillary Tumors. Phase 3 Interventional poor enrollment Actual 5
NCT03416192 Withdrawn 12 Weeks of Hemodialysis With Medium Cut-Off Filter Compared to Hemodiafiltration With Standard High-flux Filter. N/A Interventional Capacity shortage Actual 0
NCT03600805 Suspended Evaluation of Efficacy and Safety of Sarilumab in Patients With GCA Phase 3 Interventional Suspended (Due to COVID-19) Anticipated 360
NCT03600818 Suspended Evaluation of the Efficacy and Safety of Sarilumab in Patients With Polymyalgia Rheumatica Phase 3 Interventional SUSPENDED (Due to COVID-19) Anticipated 280
NCT03647566 Suspended 18F Sodium Fluoride PET/CT in Acute Aortic Syndrome Observational COVID-19 Pandemic Anticipated 80
NCT03691935 Suspended Erector Spinae Plane Block: For Pain Control in Patients Undergoing Flank Incision Phase 4 Interventional Temporary enrollment restrictions related to global pandemic. Anticipated 40
NCT03737292 Suspended Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy Phase 4 Interventional Temporarily suspended due to Pandemic. Anticipated 40
NCT03766438 Suspended Stories for Change: Digital Storytelling for Diabetes Self-Management Among Hispanic Adults N/A Interventional New recruitment is suspended during COVID-19 pandemic due to institutional guidelines. Anticipated 450
NCT03768986 Suspended A Reinforcement Intervention for Increasing HIV Testing Among At-Risk Women N/A Interventional due to COVID-19 Anticipated 334
NCT03801902 Suspended Accelerated Hypofractionated or Conventionally Fractionated Radiotherapy and Durvalumab in Treating Patients With Stage II-III Non-small Cell Lung Cancer Phase 1 Interventional Scheduled Interim Monitoring Anticipated 24
NCT03872778 Suspended [177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-NeoB Lesion Uptake Phase 1/Phase 2 Interventional Recruitment temporarily paused due to COVID-19 Anticipated 71
NCT03958799 Suspended A Study to Describe the Safety Profile and Compare the Immune Response of 4 Different Formulations of an Investigational Tdap Vaccine When Compared to Licensed Tdap Vaccine in Young Adults in Canada Phase 1 Interventional Suspended (Due to Covid-19) Anticipated 100
NCT03959826 Suspended Promoting Employment in Persons Living With HIV/AIDS N/A Interventional due to COVID-19 Anticipated 144
NCT04064463 Suspended Dual Reinforcement Contingency Management for Alcohol Use Disorders N/A Interventional due to COVID-19 Anticipated 150
NCT04099277 Terminated A Study of LY3435151 in Participants With Solid Tumors Phase 1 Interventional Study terminated due to strategic business decision by Eli Lilly and Company. Actual 2
NCT04129528 Suspended Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Adult Subjects Phase 2 Interventional Study treatment and recruitment has been paused due to COVID-19. Anticipated 102
NCT04142086 Suspended Dose-ranging Study of an Investigational Yellow Fever Candidate Vaccine in Adults Phase 1/Phase 2 Interventional Suspended (Due to Covid-19) Anticipated 572
NCT01072370 Terminated Safety and Effectiveness of Cord Blood Stem Cell Infusion for the Treatment of Cerebral Palsy in Children Phase 1/Phase 2 Interventional Actual 18
NCT02116959 Terminated Alternating Systemic Chemotherapy and Intra-Arterial Melphalan (IAM) Chemotherapy in Children With Intra-Ocular Retinoblastoma Phase 1 Interventional Low accrual Actual 6
NCT00632827 Terminated Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak) Phase 2 Interventional Manufacturing shortage of both Diftitox and Doxil Actual 21
NCT03176537 Withdrawn Periodontal Profile of Hypogonadic Men Phase 4 Interventional No eligible participants for the RCT were found Actual 0
NCT03256617 Terminated The Development of a Cognitive Reassurance Training Program N/A Interventional Recruiting beyond September 10, 2018 would mean that the training occurred more than a year in the past. For this reason, we terminated recruitment. Actual 128
NCT03261661 Suspended Improving Response to Intervention in Students With or at Risk of Reading Disabilities N/A Interventional Schools are currently closed for Covid-19 Anticipated 720
NCT03263429 Suspended Novel PET/CT Imaging Biomarkers of CB-839 in Combination With Panitumumab and Irinotecan in Patients With Metastatic and Refractory RAS Wildtype Colorectal Cancer Phase 1/Phase 2 Interventional Pause for COVID-19 Response Anticipated 40
NCT03661255 Suspended Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska N/A Interventional Enrollment is temporarily paused due to COVID-19 and is expected to resume in the future. IRB approval is not suspended Anticipated 975
NCT03672331 Suspended My Personalized Breast Screening N/A Interventional Temporary suspension since March 13 due to COVID-19 pandemic Anticipated 85000
NCT03805659 Suspended HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms N/A Interventional COVID-19 Anticipated 20
NCT03959319 Suspended Comparison of Movement Pattern Training and Manual Therapy for Prearthritic Hip Disorders N/A Interventional This study has been suspended due to the COVID-19 epidemic. The study will resume once the epidemic has ended. Anticipated 40
NCT01164150 Terminated Prospective Randomised Phase II Trial Evaluating Adjuvant Pelvic Radiotherapy Using Either IMRT or 3-Dimensional Planning for Endometrial Cancer. ICORG 09-06 Phase 2 Interventional Actual 92
NCT01949961 Terminated The Norwegian Sonothrombolysis in Acute Stroke Study Part 2 N/A Interventional Lack of funding for researchers Actual 59
NCT04349020 Suspended Patient Reported Outcomes for Acute Asthma Care Treatment Observational COVID-19 Anticipated 77
NCT04349462 Suspended Post Critical Illness Dysphagia in the Intensive Care Unit N/A Interventional Recruitment has been suspended during COVID19 Pandemic Anticipated 300
NCT02559609 Suspended Interventions for Unemployed Hazardous Drinkers N/A Interventional due to COVID-19 Anticipated 280
NCT02726880 Suspended Reducing Internet Gaming N/A Interventional due to COVID-19 Anticipated 40
NCT02777190 Suspended A Comparison of Oral Misoprostol and Vaginal Misoprostol for Cervical Ripening and Induction of Labor Phase 4 Interventional Temporarily suspended due to pandemic Anticipated 110
NCT02814591 Suspended Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy Observational [Patient Registry] Anticipated 245
NCT03473522 Suspended Effects of tDCS Combined With Therapeutic Exercises in Patients With Parkinson's Disease. Phase 2/Phase 3 Interventional We had to suspend our clinical trials due to the pandemic of COVID-19. Anticipated 30
NCT03494114 Suspended Imaging Activated Macrophages in the Lungs Phase 1 Interventional This study has been suspended due to COVID-19 Virus pandemic Anticipated 45
NCT03523156 Suspended Trachoma Elimination Study by Focused Antibiotic (TESFA) Phase 4 Interventional Study is temporarily suspended due to COVID-19 Anticipated 53384
NCT03621657 Terminated The GRAFT Study: Gut RecolonizAtion by Fecal Transplantation Phase 2 Interventional insufficient participant population Actual 1
NCT03826368 Withdrawn Hemp-Derived Botanical Dietary Supplementation During Recovery From Brain Injury Observational Lack of initial funding after approval of study Actual 0
NCT03896295 Suspended An Extension Study of MOM-M281-004 to Evaluate the Safety, Tolerability, and Efficacy of M281 Administered to Patients With Generalized Myasthenia Gravis Phase 2 Interventional This study will undergo a temporarily pause in recruitment (screening and enrollment) due to the COVID-19 pandemic. Anticipated 60
NCT03904017 Suspended The Role of Hyperoxia in Acute Ischemic Stroke N/A Interventional Covid-19 pandemic mandated suspension of research Anticipated 200
NCT04021030 Suspended Building Collaborations to Address Drug Problems in the United States and China N/A Interventional Enrollment is temporarily paused due to COVID-19; interactions/interventions with current participants continue. This is not a suspension of IRB approval. Anticipated 20
NCT04119050 Suspended Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia Phase 2/Phase 3 Interventional This study will undergo a temporarily pause in recruitment (screening and enrollment) due to the COVID-19 pandemic. Anticipated 90
NCT04252664 Suspended A Trial of Remdesivir in Adults With Mild and Moderate COVID-19 Phase 3 Interventional The epidemic of COVID-19 has been controlled well at present, no eligible patients can be recruitted. Anticipated 308
NCT04257656 Terminated A Trial of Remdesivir in Adults With Severe COVID-19 Phase 3 Interventional The epidemic of COVID-19 has been controlled well in China, no eligible patients can be enrolled at present. Actual 237
NCT04347343 Suspended Combined NMES and BFR Training After TKA N/A Interventional COVID Restrictions Anticipated 15
NCT02567227 Suspended Cognitive Remediation to Improve Mobility in Sedentary Seniors N/A Interventional The study was suspended on March 13th 2020 due to the COVID-19 pandemic. Anticipated 420
NCT02654925 Suspended Myeloid to Adipocyte Transdifferentiation in Human Cells Observational COVID-19, study will resume when we return to normal operations Anticipated 60
NCT03396978 Suspended The Influence of Gonadal Hormone Suppression on Adipocyte Lineage and the Microbiome N/A Interventional COVID-19; will resume when we return to normal operations Anticipated 20
NCT03475316 Suspended Movement Intervention for Memory Enhancement N/A Interventional The study was suspended on March 13th 2020 due to the COVID-19 pandemic. Anticipated 32
NCT02061774 Terminated Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion Phase 4 Interventional Preliminary analysis showed not clinically significant. Study ended and closed 1/11/2018 Actual 21
NCT03816644 Suspended 5-Cog Battery for Detecting Cognitive Impairment and Dementia N/A Interventional The study has been suspended as of March 13th 2020 due to the COVID-19 pandemic. Anticipated 1200
NCT04311541 Withdrawn A Study of Dexlansoprazole Modified Release (MR) in Gastroesophageal Reflux Disease (GERD) Participants in the Russian Federation Observational Business Decision; No Safety Or Efficacy Concerns Actual 0
NCT01205815 Suspended Storage and Research Use of Human Bio-specimens From Melanoma Patients and Clinical Testing for Assignment of Treatment Observational Pause for COVID 19 Response Anticipated 2500
NCT01872377 Terminated Dose Escalation Study of CyberKnife® SBRT Boost for Patients With Unresectable Locally Advanced Pancreatic Cancer N/A Interventional No longer recruiting patients to this study Actual 7
NCT02471170 Suspended Protocol to Permit the Acquisition of Circulating Tumor Material in Pancreatic Diseases Observational on hold due to COVID-19 Anticipated 100
NCT02634957 Terminated Impact of Duration Of Absolute Voice Rest on Voice Outcome After Phonomicrosurgery N/A Interventional Due to change in available resources Actual 17
NCT02653131 Terminated The Use of DPP-4 Inhibitors in Short Bowel Syndrome Phase 4 Interventional too many side-effects Actual 8
NCT03955783 Suspended Venetoclax and Selinexor in Treating Patients With Relapsed or Refractory High Risk Hematologic Malignancies Phase 1 Interventional Pause for COVID 19 response Anticipated 78
NCT02931448 Withdrawn Occult Carbon Monoxide Poisoning Detection by Pulsated Carboxymetry in an Emergency Department Observational Actual 0
NCT03360357 Withdrawn Laparoscopic Vaginal Cuff Suturing Profienciency for OBGYN Residents N/A Interventional Lack of participants to enroll. Actual 0
NCT03719560 Withdrawn Early Systemic Central Nervous System Prophylaxis in Diffuse Large B-cell Lymphoma Phase 2 Interventional lack of funding Actual 0
NCT04023227 Suspended Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC Phase 4 Interventional Recruitment temporarily paused due to COVID-19 Anticipated 900
NCT02246270 Suspended Recurrent Urinary Tract Infections and Heparin (RUTIH Trial) Phase 1/Phase 2 Interventional Due to COVID-19 Anticipated 30
NCT02256124 Terminated Effect of Lamotrigine on Cognition in NF1 Phase 2/Phase 3 Interventional Due to our experience, the small number of new inclusions, and the uncertainty regarding the COVID-19 outbreak, we have decided to discontinue the study. Actual 41
NCT02524847 Terminated Methoxsalen and Extracorporeal Photopheresis (ECP) for the Treatment of Pediatric Patients With Steroid Refractory Acute Graft Versus Host Disease Phase 3 Interventional Slow enrollment Actual 29
NCT03036566 Suspended Lithium Disilicate (CAD/CAM) Fixed Partial Dentures (FPD) Clinical Study N/A Interventional Interactions are temporarily paused due to COVID-19 and are expected to resume. Actual 30
NCT03036579 Suspended Celtra Duo Computer Assisted Design/Computer Assisted Machining (CAD/CAM) Dental Crown Study N/A Interventional Intervention/interactions are temporarily paused due to COVID-19 and are expected to resume. This is not a suspension of IRB approval Actual 100
NCT03457701 Suspended Anemia Studies in CKD: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat- Iron (ASCEND: Fe) Phase 2 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing. Anticipated 12
NCT03705013 Terminated Observational Study of Sub-populations From Cologuard Post-Approval Study (2014-01) Observational Sponsor Decision Actual 51
NCT03716817 Suspended TetricCAD Crown Clinical Study N/A Interventional Interactions are temporarily paused due to COVID-19 and are expected to resume. Actual 50
NCT03745014 Withdrawn Clinical Impact of Fast Phenotypic Antimicrobial Susceptibility Testing on Patients With Gram-Negative Rod Bacteremia N/A Interventional No sites identified with IRB approval Actual 0
NCT04038684 Suspended Healthy Eating, Activity and Reduction of Teen Stress N/A Interventional Recruitment suspended as of March 16, 2020 due to COVID-19 pandemic Anticipated 240
NCT04050683 Suspended Evaluation of Hemodynamic Parameters Following Transjugular Intrahepatic Portosystemic Shunt (TIPS) N/A Interventional Temporarily suspended per institutional directive due to COVID-19. Anticipated 24
NCT04167254 Suspended Sit Down and Play India Phase 1 Interventional Due to country-level restrictions regarding COVID19 Anticipated 100
NCT04341740 Suspended Investigating Marrow Infiltrating Lymphocytes in Renal Cell Carcinoma Early Phase 1 Interventional Due to COVID-19 Anticipated 12
NCT03639090 Suspended Mass Spectrometry in Single Bladder Cancer Cells Observational Due to COVID-19 Anticipated 10
NCT03658395 Suspended Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms N/A Interventional COVID-19 Anticipated 60
NCT03898310 Suspended UTI Prophylaxis With Cranberry Extract After Female Incontinence Surgery N/A Interventional COVID-19 Anticipated 174
NCT01636609 Terminated Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome Phase 1 Interventional In 2013 the FDA put a temporary hold on the trial and the Phase II portion of this study was cancelled. Actual 18
NCT02672475 Suspended Galunisertib and Paclitaxel in Treating Patients With Metastatic Androgen Receptor Negative (AR-) Triple Negative Breast Cancer Phase 1 Interventional Pause for COVID 19 response Anticipated 29
NCT02743793 Terminated A Cohort Study of Operationally Tolerant Allograft Recipients Observational COVID-19 pandemic and potential risks to study participants and study staff. Actual 41
NCT02819440 Suspended PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction Phase 2 Interventional Due to COVID-19 outbreak, study is temporarily suspended. Anticipated 200
NCT02892578 Terminated Systematic Screening With Electrocardiogram for Unknown Atrial Fibrillation in 65 Years Old and Above People in Nursing Home N/A Interventional The Study halted prematurely because the potential for recruitment into the associated center was reached. Actual 287
NCT02945436 Suspended Optimizing HIV Counseling and Testing and Referral Through an Adaptive Drug Use Intervention N/A Interventional halted temporarily due to the novel Coronavirus Actual 258
NCT03135171 Suspended Trastuzumab and Pertuzumab in Combination With Tocilizumab in Subjects With Metastatic HER2 Positive Breast Cancer Resistant to Trastuzumab Phase 1 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval Anticipated 20
NCT03206203 Suspended Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer Phase 2 Interventional Pause for COVID 19 Response Anticipated 185
NCT03267368 Terminated Comprehensive Care Program SBRT N/A Interventional Low enrollment. 1 pt. enrolled & withdrew at 6 wk follow-up. No further enrollment Actual 1
NCT03409419 Suspended PET Imaging of the Immune System Using Analog Probes Observational Covid-19 campus closure Anticipated 10
NCT03488225 Terminated Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia Phase 2 Interventional the study was closed early due to competing trials Actual 4
NCT03562507 Suspended Multi-center Trial of ESK981 in Combination With Nivolumab in Patients With Metastatic Renal Cell Carcinoma Phase 2 Interventional Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval. Anticipated 47
NCT03585153 Suspended Multicenter Assessment of the Pancreas in Type 1 Diabetes Observational COVID-19 outbreak Anticipated 250
NCT03628144 Withdrawn Immunonutrition to Reduce Toxicities in Non-Small Cell Lung Cancer Phase 2 Interventional Funding unavailable Actual 0
NCT03720574 Suspended Lorcaserin and Behavioral Modification for Overweight and Obesity Management in Chinese Obese Patients Phase 3 Interventional Reassess safety risks and benefits Anticipated 320
NCT03724968 Suspended Nivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II Expression Phase 2 Interventional Pause for COVID 19 Response Anticipated 36
NCT04248205 Suspended Ketamine for Post-operative Analgesia in Hemorrhoidectomy Phase 4 Interventional Due to COVID-19 Anticipated 100
NCT03736356 Suspended Long-term Health Outcomes of AE Casualties Observational [Patient Registry] The study has been paused due to the current COVID-19 pandemic. Actual 119
NCT04248543 Suspended Quantitative MRI for Functional Assessment Following SBRT for Spinal Metastases N/A Interventional COVID-19 Anticipated 20
NCT03758625 Suspended Comparison of Dendritic Cell-Based Therapeutic Vaccine Strategies for HIV Functional Cure Phase 1 Interventional Due to the COVID-19 pandemic, study has been temporarily halted and will resume in the future Anticipated 40
NCT03766009 Suspended Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making N/A Interventional COVID-19 Anticipated 1050
NCT03768531 Withdrawn Safety and Tolerability Study of Nivolumab and Cabiralizumab for Resectable Biliary Tract Cancer Phase 2 Interventional No subjects were enrolled Actual 0
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NCT03866187 Suspended A Study to Evaluate the Reactogenicity, Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' HBV (Hepatitis B Virus) Viral Vector Vaccines and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection. Phase 1 Interventional Due to the COVID-19 pandemic, this study has temporarily suspended recruitment activities. Other elements of the study are ongoing Anticipated 148
NCT03905525 Suspended Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjögren's Syndrome Phase 2 Interventional Coronavirus pandemic Anticipated 260
NCT04345874 Suspended Technical Assistance for Child and Adult Care Food Program in Family Child Care Home N/A Interventional COVID-19